losartan has been researched along with ouabain in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 5 (29.41) | 18.2507 |
| 2000's | 8 (47.06) | 29.6817 |
| 2010's | 3 (17.65) | 24.3611 |
| 2020's | 1 (5.88) | 2.80 |
| Authors | Studies |
|---|---|
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Balla, T; Csordás, G; Enyedi, P; Hajnóczky, G; Hunyady, L; Kalapos, MP; Spät, A | 1 |
| Huang, BS; Leenen, FH | 2 |
| Inagami, T; Landon, EJ; Naruse, M; Piston, DW; Tamura, M; Tani, M | 1 |
| Huang, BS; Leenen, FH; Zhang, W | 1 |
| Escalante, B; López-Sánchez, P; Martínez-Ayala, S; Rios, A; Sánchez-Mendoza, A; Vázquez-Cruz, B | 1 |
| Leenen, FH; Zhang, J | 1 |
| Budzikowski, AS; Leenen, FH | 1 |
| Alonso, MJ; Balfagón, G; Rossoni, LV; Salaices, M; Vassallo, DV; Xavier, FE | 1 |
| Hou, X; Van Huysse, JW | 1 |
| Padilha, AS; Rossoni, LV; Vassallo, DV; Xavier, FE | 1 |
| Agalakova, NI; Bagrov, AY; Fedorova, OV; Lakatta, EG; Talan, MI | 1 |
| Gabor, A; Leenen, FH | 1 |
| Caruso-Neves, C; Gomes-Quintana, E; Landgraf, SS; Lara, LS; Líbano-Soares, JD; Lopes, AG; Queiroz-Madeira, EP; Sudo, RT; Takiya, CM; Wengert, M; Zapata-Sudo, G | 1 |
| Argiolas, G; Bianchi, G; Carpini, SD; Citterio, L; Cusi, D; Ferrandi, M; Ferrari, P; Glorioso, N; Lanzani, C; Macciardi, F; Manunta, P; Messaggio, E; Salvi, E; Staessen, JA; Tripodi, G; Valentini, G | 1 |
| Couto, GK; França-Neto, A; Rossoni, LV; Xavier, FE | 1 |
1 trial(s) available for losartan and ouabain
| Article | Year |
|---|---|
Adducin- and ouabain-related gene variants predict the antihypertensive activity of rostafuroxin, part 2: clinical studies.
Topics: Androstanols; Antihypertensive Agents; Blood Pressure; Calmodulin-Binding Proteins; Female; Genetic Loci; Humans; Hydrochlorothiazide; Hypertension; Intramolecular Transferases; Kidney; Losartan; Male; Middle Aged; Mutant Proteins; Ouabain; Placebos; Polymorphism, Single Nucleotide; Systole; Time Factors; Transfection | 2010 |
16 other study(ies) available for losartan and ouabain
| Article | Year |
|---|---|
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Angiotensin-II inhibits Na+/K+ pump in rat adrenal glomerulosa cells: possible contribution to stimulation of aldosterone production.
Topics: Aldosterone; Angiotensin II; Animals; Biphenyl Compounds; Calcium; Enzyme Activation; Imidazoles; Ionomycin; Liver; Losartan; Ouabain; Phorbol Esters; Protein Kinase C; Rats; Rats, Inbred Strains; Rubidium; Rubidium Radioisotopes; Sodium; Sodium-Potassium-Exchanging ATPase; Tetrazoles; Zona Fasciculata; Zona Glomerulosa | 1992 |
Sympathoexcitatory and pressor responses to increased brain sodium and ouabain are mediated via brain ANG II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Brain; Heart Rate; Imidazoles; Immunoglobulin Fab Fragments; Injections, Intraventricular; Kidney; Losartan; Male; Ouabain; Rats; Rats, Wistar; Saline Solution, Hypertonic; Sodium; Sympathetic Nervous System; Tetrazoles | 1996 |
Ouabain increases aldosterone release from bovine adrenal glomerulosa cells: role of renin-angiotensin system.
Topics: Aldosterone; Angiotensinogen; Animals; Biphenyl Compounds; Calcium; Cattle; Cells, Cultured; Culture Media; Culture Media, Serum-Free; Horses; Imidazoles; Intracellular Membranes; Losartan; Mineralocorticoid Receptor Antagonists; Ouabain; Rats; Renin-Angiotensin System; Sheep; Swine; Tetrazoles; Zona Glomerulosa | 1996 |
Brain "ouabain" and angiotensin II in salt-sensitive hypertension in spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Brain; Guanabenz; Hemodynamics; Hypertension; Imidazoles; Immunoglobulin Fab Fragments; Injections, Intraventricular; Losartan; Male; Ouabain; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Sodium Chloride, Dietary; Tetrazoles | 1996 |
Brain renin-angiotensin system and sympathetic hyperactivity in rats after myocardial infarction.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Brain; Cardiotonic Agents; Enzyme Inhibitors; Guanabenz; Heart Failure; Heart Rate; Injections, Intraventricular; Losartan; Male; Myocardial Infarction; Nitroprusside; Ouabain; Phenylephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Stress, Physiological; Sympathetic Nervous System | 1999 |
Angiotensin II modulates ion transport in rat proximal tubules through CYP metabolites.
Topics: Adrenalectomy; Angiotensin II; Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Indomethacin; Ion Transport; Kidney Tubules, Proximal; Losartan; Male; Ouabain; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes | 2000 |
AT(1) receptor blockers prevent sympathetic hyperactivity and hypertension by chronic ouabain and hypertonic saline.
Topics: Air Movements; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Chronic Disease; Guanabenz; Heart Rate; Hypertension; Injections, Intraventricular; Losartan; Male; Ouabain; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Saline Solution, Hypertonic; Stress, Physiological; Sympathetic Nervous System; Vasoconstrictor Agents | 2001 |
ANG II in median preoptic nucleus and pressor responses to CSF sodium and high sodium intake in SHR.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Drug Interactions; Enzyme Inhibitors; Heart Rate; Injections, Intraventricular; Losartan; Male; Microinjections; Ouabain; Preoptic Area; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Saline Solution, Hypertonic; Sodium; Sodium, Dietary | 2001 |
Ouabain-induced hypertension alters the participation of endothelial factors in alpha-adrenergic responses differently in rat resistance and conductance mesenteric arteries.
Topics: Animals; Antihypertensive Agents; Blotting, Western; Cardiotonic Agents; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Losartan; Male; Mesenteric Arteries; Mesenteric Artery, Superior; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; Ouabain; Phenylephrine; Potassium Chloride; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Adrenergic, alpha; Vascular Resistance; Vasoconstrictor Agents | 2004 |
Pressor response to CSF sodium in mice: mediation by a ouabain-like substance and renin-angiotensin system in the brain.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Heart Rate; Humans; Immunoglobulin Fab Fragments; Injections, Intraventricular; Losartan; Male; Mice; Ouabain; Renin-Angiotensin System; Sodium; Sodium Chloride | 2004 |
Ouabain at nanomolar concentration promotes synthesis and release of angiotensin II from the endothelium of the tail vascular bed of spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Blood Pressure; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Drug Synergism; Drug Therapy, Combination; Enalaprilat; Endothelium, Vascular; Glucose; Hexamethonium; Injections, Intravenous; Losartan; Male; Muscle, Smooth, Vascular; Ouabain; Perfusion; Phenylephrine; Potassium Chloride; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sodium-Potassium-Exchanging ATPase; Tail; Time Factors; Tromethamine; Vasodilation | 2004 |
Brain ouabain stimulates peripheral marinobufagenin via angiotensin II signalling in NaCl-loaded Dahl-S rats.
Topics: Adrenal Cortex; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antibodies; Blood Pressure; Brain Chemistry; Bufanolides; Cells, Cultured; Losartan; Male; Natriuresis; Norepinephrine; Ouabain; Pituitary Gland; Rats; Rats, Inbred Dahl; Renin; Sodium Chloride; Sodium-Potassium-Exchanging ATPase; Vasoconstrictor Agents | 2005 |
Mechanisms in the PVN mediating local and central sodium-induced hypertension in Wistar rats.
Topics: Aldosterone; Amiloride; Angiotensins; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Cerebrospinal Fluid; Diuretics; Dose-Response Relationship, Drug; Eplerenone; Heart Rate; Hypertension; Injections, Intraventricular; Losartan; Ouabain; Paraventricular Hypothalamic Nucleus; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Mineralocorticoid; Sodium; Spironolactone | 2009 |
Na(+)-ATPase in spontaneous hypertensive rats: possible AT(1) receptor target in the development of hypertension.
Topics: Angiotensin II; Animals; Enzyme Activation; Hypertension; Kidney Tubules, Proximal; Kinetics; Losartan; Male; Ouabain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Sodium-Potassium-Exchanging ATPase | 2010 |
Cyclooxygenase-2 is a critical determinant of angiotensin II-induced vascular remodeling and stiffness in resistance arteries of ouabain-treated rats.
Topics: Angiotensin II; Animals; bcl-2-Associated X Protein; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Hydrochlorothiazide; Losartan; Matrix Metalloproteinase 2; Mesenteric Arteries; Ouabain; Rats; Rats, Wistar; Reactive Oxygen Species; Vascular Remodeling; Vascular Resistance | 2022 |