losartan has been researched along with nitrates in 21 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (19.05) | 18.2507 |
| 2000's | 12 (57.14) | 29.6817 |
| 2010's | 5 (23.81) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Arnal, JF; Michel, JB; Pueyo, ME; Rami, J | 1 |
| Borthayre, AB; Harrison, DG; Hink, U; Kurz, S; Münzel, T; Nickenig, G | 1 |
| Baldassarre, S; Berkenboom, G; Fontaine, D; Fontaine, J; Preumont, N; Unger, P | 1 |
| Cachofeiro, V; Lahera, V; Maeso, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM | 1 |
| Basso, N; González Bosc, LV; Kurnjek, ML; Müller, A; Terragno, NA | 1 |
| Johnson, RJ; Kang, DH; Mazzali, M; Ray, PE; Suga, S | 1 |
| Chang, FY; Hou, MC; Huang, YT; Lee, FY; Lee, SD; Lee, TY; Lin, HC; Liu, RS; Yang, YY | 1 |
| Berk, BC; Fox, RJ; Frame, MD; Kim, D; Mohan, A; Yan, C | 1 |
| Vaziri, ND; Wang, HW; Wang, XQ; Zhang, J; Zhou, XJ | 1 |
| Fukuyama, R; Fushiki, S; Harada, S; Hatta, T; Kido, H; Nakata, T; Oguni, A; Sasaki, S; Takeda, K | 1 |
| Duarte, J; Moreno, JM; Osuna, A; Rodríguez-Gómez, I; Sainz, J; Vargas, F; Wangensteen, R | 1 |
| Berti, F; Bianchi, M; Bonomo, S; De Gennaro Colonna, V; Ferrario, P; Fioretti, S; Manfredi, B; Muller, EE; Rigamonti, A; Rossoni, G | 1 |
| Ahmad, M; Al-Shabanah, OA; Khattab, M; Raza, M | 1 |
| Berti, F; Bonomo, S; De Gennaro Colonna, V; Fioretti, S; Manfredi, B; Muller, EE; Rigamonti, A; Rossoni, G | 1 |
| Chen, MF; Li, YJ; Luo, BL; Wang, YJ; Xie, XM; Yang, TL; Zhang, XH | 1 |
| Furuta, K; Hongo, M; Ishizaka, N; Koike, K; Matsuzaki, G; Nagai, R; Saito, K; Sakurai, R | 1 |
| de Faria, JB; de Faria, JM; Rosales, MA; Silva, KC | 1 |
| Chatzigeorgiou, A; Kamper, EF; Kamper, M; Lymberi, M; Tsimpoukidi, O | 1 |
| Budhiraja, RD; Sharma, S; Tyagi, S | 1 |
| Antunes-Rodrigues, J; Batalhão, ME; Callera, GE; Carnio, EC; Mecawi, AS; Queiroz, RH; Tirapelli, CR; Touyz, RM; Yogi, A | 1 |
| Abdel Meguid, E; El Sarha, A; Gowayed, M; Refaat, R; Salama, M | 1 |
21 other study(ies) available for losartan and nitrates
| Article | Year |
|---|---|
Angiotensin II stimulates the production of NO and peroxynitrite in endothelial cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Arginine; Bradykinin; Calcium; Calmodulin; Cells, Cultured; Endothelium, Vascular; Losartan; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sulfonamides | 1998 |
Evidence for a causal role of the renin-angiotensin system in nitrate tolerance.
Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Bosentan; Dose-Response Relationship, Drug; Drug Tolerance; Endothelium, Vascular; Female; Gene Expression; Losartan; Luminescent Measurements; Male; Multienzyme Complexes; NADH, NADPH Oxidoreductases; NADPH Oxidases; Nitrates; Nitric Oxide; Nitroglycerin; Peptidyl-Dipeptidase A; Rabbits; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Sulfonamides; Superoxides; Vasoconstriction; Vasodilation; Vasodilator Agents | 1999 |
Absence of nitrate tolerance after long-term treatment with ramipril: an endothelium-dependent mechanism.
Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Bradykinin; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Endothelium, Vascular; In Vitro Techniques; Losartan; Male; Nitrates; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Ramipril; Rats; Rats, Wistar; Superoxides; Time Factors; Vasodilator Agents | 1999 |
Differential effects of losartan and doxazosin on vascular function in senescent spontaneously hypertensive rats.
Topics: Acetylcholine; Adrenergic alpha-Antagonists; Aging; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Doxazosin; Endothelium, Vascular; Hypertension; Losartan; Male; Nitrates; Nitroprusside; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Vasodilation; Vasodilator Agents | 1999 |
Effect of chronic angiotensin II inhibition on the nitric oxide synthase in the normal rat during aging.
Topics: Aging; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cardiomegaly; Enalapril; Losartan; Male; NADPH Dehydrogenase; Nitrates; Nitric Oxide Synthase; Nitrites; Rats; Rats, Wistar; Reference Values; Time Factors | 2001 |
Angiotensin II type 1 receptor blockade ameliorates tubulointerstitial injury induced by chronic potassium deficiency.
Topics: Angiotensin Receptor Antagonists; Animals; Arginine; Chronic Disease; Dinoprostone; Kidney; Losartan; Male; Nitrates; Nitrites; Potassium Deficiency; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1 | 2002 |
Effect of 1-week losartan administration on bile duct-ligated cirrhotic rats with portal hypertension.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blotting, Western; Common Bile Duct; Enzyme Inhibitors; Hematocrit; Hypertension, Portal; Ligation; Liver Circulation; Liver Cirrhosis; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Norepinephrine; Plasma Volume; Rats; Rats, Sprague-Dawley; Renin | 2002 |
Diminished arteriolar responses in nitrate tolerance involve ROS and angiotensin II.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Drug Tolerance; Free Radical Scavengers; Losartan; Male; Metalloporphyrins; Nitrates; Nitric Oxide; Nitric Oxide Donors; Nitroglycerin; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Superoxide Dismutase; Vasodilation | 2002 |
Association of renal injury with nitric oxide deficiency in aged SHR: prevention by hypertension control with AT1 blockade.
Topics: Aging; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Arterioles; Hypertension, Renal; Immunoenzyme Techniques; Kidney Failure, Chronic; Kidney Glomerulus; Losartan; Male; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Tyrosine | 2002 |
Contrasting effects of angiotensin type 1 and 2 receptors on nitric oxide release under pressure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Apoptosis; Bradykinin; Cell Count; Cells, Cultured; Endothelium, Vascular; Gene Expression; Glyceraldehyde-3-Phosphate Dehydrogenases; In Vitro Techniques; Losartan; Male; Nitrates; Nitric Oxide; Nitrites; Oxygen; Pressure; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2002 |
Increased pressor sensitivity to chronic nitric oxide deficiency in hyperthyroid rats.
Topics: Angiotensin II; Animals; Blood Pressure; Creatinine; Enzyme Inhibitors; Heart Rate; Hyperthyroidism; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Nitrites; Potassium; Proteinuria; Rats; Rats, Wistar; Sodium; Thyroxine | 2003 |
Angiotensin-converting enzyme inhibition and angiotensin AT1-receptor antagonism equally improve endothelial vasodilator function in L-NAME-induced hypertensive rats.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Enalapril; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Systole; Vasoconstriction; Vasodilation; Vasodilator Agents | 2005 |
Effects of losartan on blood pressure, oxidative stress, and nitrate/nitrite levels in the nitric oxide deficient hypertensive rats.
Topics: Analysis of Variance; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Body Weight; Creatinine; Dose-Response Relationship, Drug; Heart; Hypertension; Kidney; Lipid Peroxidation; Losartan; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitrites; Organ Size; Oxidative Stress; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Time Factors | 2004 |
Angiotensin II type 1 receptor antagonism improves endothelial vasodilator function in L-NAME-induced hypertensive rats by a kinin-dependent mechanism.
Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin B2 Receptor Antagonists; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Hypertension; Kinins; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Nitroprusside; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B2; RNA, Messenger; Vasodilation | 2006 |
Role of asymmetric dimethylarginine in inflammatory reactions by angiotensin II.
Topics: Amidohydrolases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Arginine; Cell Adhesion; Cells, Cultured; Culture Media, Conditioned; Endothelial Cells; Endothelium, Vascular; Gene Expression Regulation; Humans; Interleukin-8; Losartan; Monocytes; NF-kappa B; Nitrates; Nitric Oxide; Nitrites; Protein-Arginine N-Methyltransferases; Reactive Oxygen Species; Receptors, Interleukin-8B; Repressor Proteins; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Umbilical Veins; Vasculitis; Vasodilation | 2007 |
Comparison of vasculoprotective effects of benidipine and losartan in a rat model of metabolic syndrome.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta, Thoracic; Calcium Channel Blockers; Dihydropyridines; Endothelium, Vascular; Fibrosis; Heart; In Vitro Techniques; Losartan; Metabolic Syndrome; Muscle Relaxation; Myocardium; Nitrates; Nitrites; Rats; Rats, Inbred OLETF; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2008 |
Reduction of inducible nitric oxide synthase via angiotensin receptor blocker prevents the oxidative retinal damage in diabetic hypertensive rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Animals; Biomarkers; Deoxyguanosine; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Down-Regulation; Losartan; Male; Nitrates; Nitric Oxide Synthase Type II; Nitrites; Osmolar Concentration; Oxidation-Reduction; Rats; Rats, Inbred SHR; Retina; Superoxide Dismutase; Tyrosine; Up-Regulation | 2010 |
The antioxidant effect of angiotensin II receptor blocker, losartan, in streptozotocin-induced diabetic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Intercellular Adhesion Molecule-1; Losartan; Male; Malondialdehyde; Nitrates; Nitric Oxide; Pancreas; Rats; Rats, Wistar; Streptozocin; Vascular Endothelial Growth Factor A | 2010 |
Effect of phosphatidylinositol 3-kinase-γ inhibitor CAY10505 in hypertension, and its associated vascular endothelium dysfunction in rats.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Atorvastatin; Blood Pressure; Desoxycorticosterone; Endothelium, Vascular; Female; Glutathione; Heptanoic Acids; Hypertension; Losartan; Male; Nitrates; Nitrites; Phosphoinositide-3 Kinase Inhibitors; Pyrroles; Rats; Rats, Wistar; Thiazolidinediones | 2012 |
Acute ethanol intake induces superoxide anion generation and mitogen-activated protein kinase phosphorylation in rat aorta: a role for angiotensin type 1 receptor.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Blood Pressure; Ethanol; Gene Expression Regulation; Losartan; Male; Mitogen-Activated Protein Kinase Kinases; NADPH Oxidases; Nitrates; Oxidative Stress; Phosphorylation; Protein Subunits; Protein Transport; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxides | 2012 |
Evaluation of the effect of losartan and methotrexate combined therapy in adjuvant-induced arthritis in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arthritis, Experimental; C-Reactive Protein; Drug Therapy, Combination; Hindlimb; Interleukin-1beta; Losartan; Male; Methotrexate; Nitrates; Nitrites; Rats; Rats, Sprague-Dawley; Serum Albumin; Transaminases; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A | 2013 |