losartan has been researched along with nicardipine in 17 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (35.29) | 18.2507 |
| 2000's | 4 (23.53) | 29.6817 |
| 2010's | 5 (29.41) | 24.3611 |
| 2020's | 2 (11.76) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Norman, BH | 1 |
| Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF | 1 |
| Jover, B; Mimran, A; Nafrialdi, N | 1 |
| Hayashi, M; Ichihara, A; Kobori, H; Miyashita, Y; Saruta, T; Suzuki, H; Takenaka, T | 1 |
| Baan, J; Chang, PC; Pfaffendorf, M; van Zwieten, PA; Vermeij, P | 1 |
| Hayashi, M; Ichihara, A; Kobori, H; Miyashita, Y; Saruta, T | 1 |
| Baan, J; Chang, PC; Pfaffendorf, M; van der Wal, AC; van Zwieten, PA | 1 |
| Bellissant, E; Durand-Castel, X; Goineau, S; Guillo, P; Pape, D | 1 |
| Fan, YP; Puri, RN; Rattan, S | 1 |
| Broekelmann, TJ; Halabi, CM; Knutsen, RH; Kozel, BA; Mecham, RP; Ye, L | 1 |
3 review(s) available for losartan and nicardipine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Drug Induced Liver Injury (DILI). Mechanisms and Medicinal Chemistry Avoidance/Mitigation Strategies.
Topics: Animals; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Drug Discovery; Drug Evaluation, Preclinical; Hepatocytes; Humans; Liver; Mitochondria, Liver; Pharmaceutical Preparations; Risk Assessment; Tissue Distribution | 2020 |
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells | 2022 |
14 other study(ies) available for losartan and nicardipine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index | 2014 |
Endogenous vasoactive systems and the pressor effect of acute N omega-nitro-L-arginine methyl ester administration.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Animals; Arginine; Biphenyl Compounds; Blood Pressure; Desoxycorticosterone; Diet, Sodium-Restricted; Enalapril; Imidazoles; Losartan; Male; NG-Nitroarginine Methyl Ester; Nicardipine; Nitric Oxide; Rats; Rats, Wistar; Renin-Angiotensin System; Tetrazoles; Vasoconstriction | 1994 |
Role of the renin-angiotensin system in cardiac hypertrophy induced in rats by hyperthyroidism.
Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Blood; Cardiomegaly; Hemodynamics; Hyperthyroidism; Imidazoles; Losartan; Male; Myocardium; Nephrectomy; Nicardipine; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sympathectomy, Chemical; Tetrazoles; Thyroxine | 1997 |
Venoconstriction by angiotensin II in the human forearm is inhibited by losartan but not by nicardipine.
Topics: Adult; Angiotensin II; Antihypertensive Agents; Arteries; Forearm; Humans; Losartan; Male; Nicardipine; Regional Blood Flow; Vasoconstriction; Veins | 1998 |
Mechanism of hyperthyroidism-induced renal hypertrophy in rats.
Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Gene Expression; Hyperthyroidism; Hypertrophy; Kidney; Losartan; Male; Nicardipine; Rats; Rats, Sprague-Dawley; Renin; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Thyroxine | 1998 |
Influence of losartan and nicardipine on the contractile responses of human subcutaneous arteries and veins to angiotensin II.
Topics: Acetylcholine; Adult; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Arteries; Blood Vessels; Calcium Channel Blockers; Dose-Response Relationship, Drug; Female; Humans; In Vitro Techniques; Losartan; Nicardipine; Phenylephrine; Potassium; Skin; Vasoconstriction; Vasoconstrictor Agents; Vasodilator Agents; Veins | 1999 |
Endothelin, but not angiotensin II, contributes to the hypoxic contractile response of large isolated pulmonary arteries in the rat.
Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Azepines; Bosentan; Calcium; Calcium Channel Blockers; Endothelin Receptor Antagonists; Endothelins; Endothelium, Vascular; Extracellular Space; Glycopeptides; Hypoxia; In Vitro Techniques; Indoles; Lisinopril; Losartan; Male; Muscle Contraction; Muscle, Smooth, Vascular; Nicardipine; Pulmonary Artery; Rats; Rats, Wistar; Sulfonamides | 1999 |
Comparison of angiotensin II (Ang II) effects in the internal anal sphincter (IAS) and lower esophageal sphincter smooth muscles.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Anal Canal; Angiotensin II; Animals; Dose-Response Relationship, Drug; Drug Combinations; Esophagus; Female; Flavonoids; Genistein; Imidazoles; Losartan; Male; Muscle Contraction; Muscle, Smooth; Nicardipine; Opossums; Pyridines; Rabbits; Species Specificity; Tyrphostins | 2002 |
Chronic antihypertensive treatment improves pulse pressure but not large artery mechanics in a mouse model of congenital vascular stiffness.
Topics: Animals; Antihypertensive Agents; Arteries; Blood Pressure; Elastin; Losartan; Mice; Mice, Inbred C57BL; Nicardipine; Propranolol; Vascular Stiffness; Williams Syndrome | 2015 |