Compounds > losartan

losartan and mk 996

losartan has been researched along with mk 996 in 6 studies

Research

Studies (6)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	4 (66.67)	18.2507
2000's	0 (0.00)	29.6817
2010's	2 (33.33)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Chakravarty, PK; Chang, RS; Chen, A; Chen, TB; Faust, KA; Gable, RA; Kivlighn, SD; Lotti, VJ; Naylor, EM; Zingaro, GJ	1
Goldberg, MR; Greenlee, WJ; Irvin, JD; Prendergast, K; Smith, RD; Timmermans, PB; Wexler, RR	1
Giridhar, R; Murumkar, P; Naik, P; Yadav, MR	1
Meanwell, NA	1
Broten, TP; Chakravarty, PK; Gabel, RA; Greenlee, WJ; Kivlighn, SD; Naylor, EM; Patchett, AA; Schaffer, LW; Schorn, TW; Zingaro, GJ	1
Barbera, FA; Bernard, R; Bozarth, TA; Gibson, RE; Herblin, WF; Watson, CA; Wong, PC	1

Reviews

2 review(s) available for losartan and mk 996

Article	Year
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy. Journal of medicinal chemistry, 1996, Feb-02, Volume: 39, Issue:3 Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Receptors, Angiotensin; Structure-Activity Relationship	1996
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. Bioorganic & medicinal chemistry, 2010, Dec-15, Volume: 18, Issue:24 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan	2010

Other Studies

4 other study(ies) available for losartan and mk 996

Article	Year
A highly potent, orally active imidazo[4,5-b]pyridine biphenylacylsulfonamide (MK-996; L-159,282): a new AT1-selective angiotensin II receptor antagonist. Journal of medicinal chemistry, 1994, Nov-25, Volume: 37, Issue:24 Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Dogs; Imidazoles; Macaca mulatta; Pyridines; Rats	1994
Synopsis of some recent tactical application of bioisosteres in drug design. Journal of medicinal chemistry, 2011, Apr-28, Volume: 54, Issue:8 Topics: Cytochrome P-450 Enzyme System; Drug Design	2011
In vivo pharmacology of a novel AT1 selective angiotensin II receptor antagonist, MK-996. American journal of hypertension, 1995, Volume: 8, Issue:1 Topics: Administration, Oral; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Bradykinin; Dogs; Enalapril; Female; Imidazoles; Injections, Intravenous; Losartan; Macaca mulatta; Male; Nitroglycerin; Pan troglodytes; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles	1995
Nonpeptide angiotensin II receptor antagonists: in vivo inhibition of [125I-Sar1,Ile8]angiotensin II binding by losartan, EXP597 and L-159,282 in rats. Clinical and experimental hypertension (New York, N.Y. : 1993), 1996, Volume: 18, Issue:2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Imidazoles; Losartan; Male; Pyridines; Rats; Rats, Sprague-Dawley; Sulfonamides; Tetrazoles	1996