losartan has been researched along with malondialdehyde in 43 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (4.65) | 18.2507 |
| 2000's | 16 (37.21) | 29.6817 |
| 2010's | 23 (53.49) | 24.3611 |
| 2020's | 2 (4.65) | 2.80 |
| Authors | Studies |
|---|---|
| Attias, J; Breslow, JL; Hayek, T; Keidar, S; Smith, J | 1 |
| Kedziora-Kornatowska, K | 1 |
| Agarwal, R | 1 |
| Arinsoy, T; Derici, U; Donmez, G; Erbas, D; Hasanoglu, E; Onk, A; Sindel, S | 1 |
| Chamorro, V; Duarte, J; O'Valle, F; Osuna, A; Sainz, J; Vargas, F; Wangensteen, R | 1 |
| Ahn, JY; Ahn, TH; Choi, IS; Chung, WJ; Han, SH; Kang, MH; Koh, KK; Quon, MJ; Seo, YH; Shin, EK | 1 |
| Gottsäter, A; Ohlin, AK; Ohlin, H; Tingberg, E | 1 |
| Lu, Y; Yao, HW; Zhao, MH; Zhu, JP | 1 |
| Dhalla, NS; Liu, X; Sethi, R; Suzuki, H; Takeda, N; Tappia, PS | 1 |
| Aghaeishahsavari, M; Argani, H; Ghorbanihaghjo, A; Noroozianavval, M; Rashtchizadeh, N; Veisi, P | 1 |
| Alonso, MJ; Alvarez, Y; Beltrán, A; Briones, AM; García-Redondo, A; Hernanz, R; Pérez-Girón, JV; Salaices, M | 1 |
| Liu, LY; Liu, YH; Song, T; Wu, SJ; You, Y | 1 |
| Chen, N; Li, JJ; Xue, XD | 1 |
| Aghaeishahsavari, M; Argani, H; Babaei, H; Ghorbanihaghjo, A; Mesgari, M; Noroozianavval, M; Rashtchizadeh, N; Safa, J; Veisi, P | 1 |
| Akita, Y; Imamura, H; Iwasaka, T; Matsuhisa, S; Moriguchi, A; Okazaki, T; Otani, H; Sato, D; Yamashita, K | 1 |
| Hu, X; Qiao, WL; Shi, Y; Wei, EQ; Xu, M; Zhang, JF; Zhang, YM | 1 |
| Azuma, K; Dejima, T; Ishigami, T; Kanaoka, T; Maeda, A; Masuda, S; Mitsuhashi, H; Ohnishi, T; Ohsawa, M; Okano, Y; Ozawa, M; Tamura, K; Tokita, Y; Toya, Y; Tsurumi-Ikeya, Y; Umemura, S; Wakui, H; Yamauchi, J; Yanagi, M | 1 |
| Aizawa, Y; Arozal, W; Kodama, M; Ma, M; Suzuki, K; Tachikawa, H; Thandavarayan, RA; Veeraveedu, PT; Watanabe, K | 1 |
| Chatzigeorgiou, A; Kamper, EF; Kamper, M; Lymberi, M; Tsimpoukidi, O | 1 |
| de Cavanagh, EM; Ferder, LF; Ferder, MD; Inserra, F; Stella, IY; Toblli, JE | 1 |
| Adesanoye, OA; Bamidele, TO; Ekor, M; Kale, OE; Odewabi, AO; Oritogun, KS | 1 |
| Feng, J; Luo, H; Qiu, Y; Wu, F; Yu, F; Zhou, W | 1 |
| Bigagli, E; Lodovici, M; Manni, ME; Raimondi, L; Zazzeri, M | 1 |
| Banoglu, ZN; Dengiz, GO; Kandemir, NO; Kurcer, Z; Mungan, G; Ozacmak, VH; Turkili, B | 1 |
| Kobara, M; Nakata, T; Noda, K; Toba, H; Tojo, C; Wang, J | 1 |
| Kong, X; Li, FX; Su, Q; Wu, HB; Zhang, DY; Zhang, Y | 1 |
| Bild, W; Ciobica, A; Hritcu, L; Stefanescu, C | 1 |
| Miao, J; Wang, S; Zhang, W; Zhang, Y | 1 |
| Adem, A; Ali, MA; Amir, N; Kazzam, E; Nyberg, F | 1 |
| Gong, CX; Hu, J; Liu, X; Luo, H; Wang, JZ; Wang, XC; Wang, Z; Xia, Y; Yu, G; Zeng, K; Zhou, XW | 1 |
| Ahghari, P; Bakhshi, E; Kadkhodaee, M; Ranjbaran, M; Rastegar, T; Seifi, B | 1 |
| El-Moselhy, MA; Mangoura, SA; Sleem, M; Taye, A | 1 |
| Dhein, S; Hoyer, A; Kempfert, J; Mohr, FW; Pritzwald-Stegmann, P | 1 |
| Bigagli, E; Di Serio, C; Lodovici, M; Raimondi, L; Tarantini, F | 1 |
| Hernández-Fonseca, JP; Mosquera, J; Pedreañez, A; Peña, C; Viera, N | 1 |
| Chung, YH; Ho, YS; Jang, CG; Jeong, JH; Kim, DJ; Kim, HC; Lee, YJ; Lei, XG; Mai, HN; Nah, SY; Nam, Y; Nguyen, TT; Shin, EJ; Yu, DY | 1 |
| Abd-Eldayem, AM; Abdel-Zaher, AO; El-Refaiy, AEM; Farghaly, HSM | 2 |
| Ali, SS; Gazzaz, ZJ; Ibraheem, MS; Murad, HA | 1 |
| Ebrahimzadeh Bideskan, A; Hosseinian, S; Khajavi Rad, A; Sadeghnia, HR; Samadi Noshahr, Z; Shafei, MN; Shahraki, S; Soukhtanloo, M | 1 |
| Abo-Saif, AA; Abo-Youssef, AM; Gaafar, AG; Khalaf, MM | 1 |
| Afify, EH; Osman, EY; Sokar, SS | 1 |
| Higashi, Y; Karashima, T; Nagao, Y; Saito, M; Shimizu, S; Shimizu, T | 1 |
6 trial(s) available for losartan and malondialdehyde
| Article | Year |
|---|---|
Proinflammatory effects of oxidative stress in chronic kidney disease: role of additional angiotensin II blockade.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biomarkers; Blood Pressure; Chemokine CCL2; Chronic Disease; Cross-Over Studies; Cytokines; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Female; Glomerular Filtration Rate; Glomerulonephritis; Humans; Kidney Failure, Chronic; Lipids; Losartan; Male; Malondialdehyde; Middle Aged; Oxidative Stress; Proteinuria; Receptor, Angiotensin, Type 1; Serum Albumin | 2003 |
Additive beneficial effects of losartan combined with simvastatin in the treatment of hypercholesterolemic, hypertensive patients.
Topics: Adiponectin; Angiotensin II Type 1 Receptor Blockers; Biomarkers; Blood Pressure; C-Reactive Protein; Chemokine CCL2; Cross-Over Studies; Double-Blind Method; Drug Synergism; Drug Therapy, Combination; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Insulin Resistance; Intercellular Signaling Peptides and Proteins; Lipids; Losartan; Male; Malondialdehyde; Middle Aged; Simvastatin; Vasodilation | 2004 |
Lipid peroxidation is not increased in heart failure patients on modern pharmacological therapy.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Captopril; Comorbidity; Delayed-Action Preparations; Dinoprost; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Lipid Peroxidation; Losartan; Male; Malondialdehyde; Middle Aged; Myocardial Infarction; Natriuretic Peptide, Brain; Nitric Oxide Donors; Oxidative Stress; Ramipril; Stroke Volume; Ultrasonography; Ventricular Dysfunction, Left | 2006 |
Enalapril and losartan affect lipid peroxidation in renal transplant recipients with renin-angiotensin system polymorphisms.
Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Cross-Over Studies; Enalapril; Female; Humans; Kidney Transplantation; Lipid Peroxidation; Losartan; Male; Malondialdehyde; Peptidyl-Dipeptidase A; Polymerase Chain Reaction; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sequence Analysis, DNA | 2007 |
Prevention of DNA damage in renal transplantation by losartan and enalapril: the role of renin-angiotensin system polymorphisms.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Ataxia Telangiectasia Mutated Proteins; Biomarkers; Cell Cycle Proteins; Deoxyguanosine; DNA Damage; Enalapril; Female; Humans; Kidney Transplantation; Lipid Peroxidation; Losartan; Male; Malondialdehyde; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Protein Serine-Threonine Kinases; Renin-Angiotensin System | 2008 |
Effect of losartan on ambulatory short-term blood pressure variability and cardiovascular remodeling in hypertensive patients on hemodialysis.
Topics: Adiponectin; Aged; Angiotensin II Type 1 Receptor Blockers; Ankle; Antihypertensive Agents; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Circadian Rhythm; Female; Glycation End Products, Advanced; Humans; Hypertension; Hypertrophy, Left Ventricular; Lipoproteins, LDL; Losartan; Male; Malondialdehyde; Middle Aged; Natriuretic Peptide, Brain; Regression Analysis; Renal Dialysis; Time Factors; Treatment Outcome; Ultrasonography; Ventricular Remodeling | 2009 |
37 other study(ies) available for losartan and malondialdehyde
| Article | Year |
|---|---|
The angiotensin-II receptor antagonist, losartan, inhibits LDL lipid peroxidation and atherosclerosis in apolipoprotein E-deficient mice.
Topics: Angiotensin Receptor Antagonists; Animals; Apolipoproteins E; Arteriosclerosis; Biphenyl Compounds; Copper Sulfate; Imidazoles; Lipid Peroxidation; Lipoproteins, LDL; Losartan; Malondialdehyde; Mice; Mice, Mutant Strains; Oxidation-Reduction; Oxidative Stress; Renin; Tetrazoles | 1997 |
Effect of angiotensin convertase inhibitors and AT1 angiotensin receptor antagonists on the development of oxidative stress in the kidney of diabetic rats.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Catalase; Diabetes Mellitus, Experimental; Glutathione Peroxidase; Kidney; Lipid Peroxidation; Losartan; Male; Malondialdehyde; Organ Size; Oxidative Stress; Rats; Rats, Wistar; Streptozocin; Superoxide Dismutase | 1999 |
The effects of losartan and enalapril therapies on the levels of nitric oxide, malondialdehyde, and glutathione in patients with essential hypertension.
Topics: Adult; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Enalapril; Female; Glutathione; Humans; Hypertension; Losartan; Male; Malondialdehyde; Middle Aged; Nitric Oxide; Receptor, Angiotensin, Type 1 | 2002 |
Protective effects of the angiotensin II type 1 (AT1) receptor blockade in low-renin deoxycorticosterone acetate (DOCA)-treated spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Cardiomegaly; Desoxycorticosterone; Endothelins; Hypertension; Isoprostanes; Kidney; Losartan; Male; Malondialdehyde; Proteinuria; Rats; Rats, Inbred SHR; Renin | 2004 |
Losartan attenuates bleomycin-induced pulmonary fibrosis in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antibiotics, Antineoplastic; Bleomycin; Body Weight; Glucocorticoids; Hydroxyproline; Losartan; Lung; Male; Malondialdehyde; Prednisone; Pulmonary Fibrosis; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Transforming Growth Factor beta; Transforming Growth Factor beta1; Weight Gain | 2006 |
Blockade of the renin-angiotensin system attenuates sarcolemma and sarcoplasmic reticulum remodeling in chronic diabetes.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Diabetes Mellitus, Experimental; Diabetic Angiopathies; Enalapril; Losartan; Male; Malondialdehyde; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sarcolemma; Sarcoplasmic Reticulum; Ventricular Dysfunction, Left; Ventricular Function, Left | 2006 |
Losartan reduces the increased participation of cyclooxygenase-2-derived products in vascular responses of hypertensive rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; Blotting, Western; Cyclooxygenase 2; Desoxycorticosterone; Dinoprost; Hypertension; In Vitro Techniques; Isometric Contraction; Losartan; Male; Malondialdehyde; Muscle Contraction; Muscle, Smooth, Vascular; Prostaglandins I; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger | 2007 |
Impairment of endothelium-dependent relaxation of rat aortas by homocysteine thiolactone and attenuation by captopril.
Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Captopril; Dose-Response Relationship, Drug; Enalaprilat; Endothelium, Vascular; Free Radicals; Homocysteine; Losartan; Malondialdehyde; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasodilation | 2007 |
[Effect of losartan on lung fibrosis in neonatal rats with hyperoxia-induced chronic lung disease].
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Animals, Newborn; Bronchopulmonary Dysplasia; Humans; Hydroxyproline; Hyperoxia; Infant, Newborn; Losartan; Lung; Malondialdehyde; Pulmonary Fibrosis; Rats; Rats, Wistar; Superoxide Dismutase | 2007 |
Angiotensin II type 1 receptor blocker preserves tolerance to ischemia-reperfusion injury in Dahl salt-sensitive rat heart.
Topics: Aldehydes; Amidines; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Benzylamines; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Hypertension; Losartan; Male; Malondialdehyde; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Phosphorylation; Rats; Rats, Inbred Dahl; Sodium Chloride, Dietary; Tiopronin; Up-Regulation; Ventricular Function, Left | 2008 |
The role of nuclear factor-kappaB in the effect of angiotensin II in the paraventricular nucleus in protecting the gastric mucosa from ischemia-reperfusion injury in rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Dose-Response Relationship, Drug; Gastric Mucosa; I-kappa B Proteins; Losartan; Male; Malondialdehyde; NF-kappa B; NF-KappaB Inhibitor alpha; Paraventricular Hypothalamic Nucleus; Phosphorylation; Pyrrolidines; Rats; Rats, Sprague-Dawley; Regional Blood Flow; Reperfusion Injury; Superoxide Dismutase; Thiocarbamates | 2008 |
Effects of angiotensin receptor blocker on oxidative stress and cardio-renal function in streptozotocin-induced diabetic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Blood Urea Nitrogen; Blotting, Western; Cardiomyopathies; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Fibrosis; Heart; Kidney; Lipid Peroxidation; Losartan; Male; Malondialdehyde; Myocardium; Oxidative Stress; Proteinuria; Rats; Rats, Sprague-Dawley; Streptozocin | 2009 |
The antioxidant effect of angiotensin II receptor blocker, losartan, in streptozotocin-induced diabetic rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental; Intercellular Adhesion Molecule-1; Losartan; Male; Malondialdehyde; Nitrates; Nitric Oxide; Pancreas; Rats; Rats, Wistar; Streptozocin; Vascular Endothelial Growth Factor A | 2010 |
Vascular structure and oxidative stress in salt-loaded spontaneously hypertensive rats: effects of losartan and atenolol.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Atenolol; Hypertension; Losartan; Male; Malondialdehyde; Nitric Oxide Synthase Type III; Oxidative Stress; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renal Artery; Renin-Angiotensin System; Sodium Chloride, Dietary; Superoxides | 2010 |
Pharmacologic inhibition of the renin-angiotensin system did not attenuate hepatic toxicity induced by carbon tetrachloride in rats.
Topics: Alanine Transaminase; Alkaline Phosphatase; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aspartate Aminotransferases; Carbon Tetrachloride; Chemical and Drug Induced Liver Injury; Enalapril; Glutathione; Liver; Losartan; Malondialdehyde; Organ Size; Rats; Rats, Wistar | 2011 |
Down-regulation of DDAH2 and eNOS induces endothelial dysfunction in sinoaortic-denervated rats.
Topics: Amidohydrolases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Aorta; Apoptosis; Denervation; Down-Regulation; Endothelial Cells; Gene Expression Regulation, Enzymologic; Hemodynamics; Losartan; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Vasodilation | 2011 |
The protective effect of losartan in the nephropathy of the diabetic rat includes the control of monoamine oxidase type A activity.
Topics: Aldehyde Dehydrogenase; Angiotensin II Type 1 Receptor Blockers; Animals; Catalase; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Losartan; Malondialdehyde; Monoamine Oxidase; Oxidative Stress; Protective Agents; Protein Carbonylation; Rats; Rats, Wistar; Superoxide Dismutase | 2012 |
Role of angiotensin and endothelin in testicular ischemia reperfusion injury.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Bosentan; Enalapril; Endothelin Receptor Antagonists; Endothelins; Losartan; Male; Malondialdehyde; Rats; Rats, Wistar; Reperfusion Injury; Statistics, Nonparametric; Sulfonamides; Testis | 2012 |
Telmisartan inhibits vascular dysfunction and inflammation via activation of peroxisome proliferator-activated receptor-γ in subtotal nephrectomized rat.
Topics: Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Anilides; Animals; Aorta; Benzimidazoles; Benzoates; Blood Urea Nitrogen; Disease Models, Animal; Inflammation; Kidney Failure, Chronic; Losartan; Male; Malondialdehyde; Nephrectomy; PPAR gamma; Rats; Rats, Wistar; Telmisartan; Vasodilation | 2012 |
Combination therapy with losartan and pioglitazone additively reduces renal oxidative and nitrative stress induced by chronic high fat, sucrose, and sodium intake.
Topics: Animals; Body Weight; Diet, High-Fat; Dietary Sucrose; Drug Synergism; Drug Therapy, Combination; Gene Expression Regulation, Enzymologic; Immunohistochemistry; Kidney; Losartan; Male; Malondialdehyde; NADPH Oxidases; Nitrosation; Oxidation-Reduction; Oxidative Stress; Pioglitazone; Rats; Rats, Sprague-Dawley; RNA, Messenger; Sodium, Dietary; Superoxide Dismutase; Thiazolidinediones; Tyrosine | 2012 |
Inhibition of central angiotensin II enhances memory function and reduces oxidative stress status in rat hippocampus.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Avoidance Learning; Behavior, Animal; Captopril; Glutathione Peroxidase; Hippocampus; Imidazoles; Lipid Peroxidation; Losartan; Male; Malondialdehyde; Maze Learning; Memory; Memory, Short-Term; Oxidative Stress; Psychomotor Performance; Pyridines; Rats; Rats, Wistar; Superoxide Dismutase | 2013 |
The protective effects of beta-casomorphin-7 against glucose -induced renal oxidative stress in vivo and vitro.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Glucose; Cell Line; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Endorphins; Epithelial Cells; Glucagon; Glutathione Peroxidase; Hydrogen Peroxide; Insulin; Isoenzymes; Kidney; Losartan; Male; Malondialdehyde; Oxidative Stress; Peptide Fragments; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Superoxide Dismutase | 2013 |
Effects of dehydration and blockade of angiotensin II AT1 receptor on stress hormones and anti-oxidants in the one-humped camel.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Camelus; Catecholamines; Dehydration; Glutathione; Hydrocortisone; Losartan; Male; Malondialdehyde; Receptor, Angiotensin, Type 1; Stress, Physiological; Water Deprivation | 2013 |
Losartan-induced hypotension leads to tau hyperphosphorylation and memory deficit.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Avoidance Learning; Blood Pressure; Dendritic Spines; Disease Models, Animal; Hypertension; Losartan; Male; Malondialdehyde; Maze Learning; Memory Disorders; Neurons; Oxidative Stress; Phosphorylation; Rats; Rats, Sprague-Dawley; Reaction Time; Superoxide Dismutase; tau Proteins | 2014 |
Enhancement of renal oxidative stress by injection of angiotensin II into the paraventricular nucleus in renal ischemia-reperfusion injury.
Topics: Acetylglucosaminidase; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Creatinine; Kidney; Losartan; Male; Malondialdehyde; Microinjections; Oxidative Stress; Paraventricular Hypothalamic Nucleus; Rats, Sprague-Dawley; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase | 2014 |
Combination therapy with losartan and L-carnitine protects against endothelial dysfunction of streptozotocin-induced diabetic rats.
Topics: Acetylcholine; Animals; Aorta; Carnitine; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Endothelium, Vascular; Losartan; Male; Malondialdehyde; Nitric Oxide; Nitric Oxide Synthase Type III; Oxidative Stress; Protective Agents; Rats; Rats, Wistar; Receptors, Angiotensin; Streptozocin; Superoxides; Tumor Necrosis Factor-alpha; Vasodilation; Vasodilator Agents | 2014 |
Acute hemodynamic effects of angiotensin- converting enzyme inhibition after prolonged cardiac arrest with Bretschneider's solution.
Topics: Adenosine Triphosphate; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Endothelin Receptor Antagonists; Glucose; Heart Arrest; Hemodynamics; Losartan; Male; Malondialdehyde; Mannitol; Myocardial Reperfusion Injury; Oxygen Consumption; Peptides, Cyclic; Potassium Chloride; Procaine; Rabbits | 2014 |
Losartan reduces oxidative damage to renal DNA and conserves plasma antioxidant capacity in diabetic rats.
Topics: 8-Hydroxy-2'-Deoxyguanosine; Adiponectin; Angiotensin II Type 1 Receptor Blockers; Animals; Antioxidants; Deoxyguanosine; Diabetes Mellitus, Experimental; DNA; DNA Damage; Enzyme-Linked Immunosorbent Assay; Hyperglycemia; Kidney; Lipids; Losartan; Malondialdehyde; Oxidative Stress; Oxygen; Random Allocation; Rats; Rats, Wistar; Reactive Oxygen Species | 2015 |
Renal oxidative stress and renal CD8(+) T-cell infiltration in mercuric chloride-induced nephropathy in rats: role of angiotensin II.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Catalase; CD8-Positive T-Lymphocytes; Enalapril; Glutathione; Kidney; Kidney Diseases; Losartan; Male; Malondialdehyde; Mercuric Chloride; Necrosis; Oxidative Stress; Rats; Rats, Sprague-Dawley | 2016 |
Genetic depletion of glutathione peroxidase-1 potentiates nephrotoxicity induced by multiple doses of cocaine via activation of angiotensin II AT1 receptor.
Topics: Animals; bcl-2-Associated X Protein; Chromones; Cocaine; Female; Gene Expression Regulation; Glutathione; Glutathione Peroxidase; Glutathione Peroxidase GPX1; Kidney; Losartan; Male; Malondialdehyde; Mice; Mice, Knockout; Morpholines; NF-kappa B; Oxidation-Reduction; Oxidative Stress; Phosphatidylinositol 3-Kinases; Phosphoinositide-3 Kinase Inhibitors; Protein Carbonylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins c-akt; Pyrrolidines; Receptor, Angiotensin, Type 1; Signal Transduction; Thiocarbamates | 2016 |
Protective effect of the standardized extract of ginkgo biloba (EGb761) against hypertension with hypercholesterolemia-induced renal injury in rats: Insights in the underlying mechanisms.
Topics: Animals; Blood Pressure; Creatinine; Diastole; Ginkgo biloba; Glutathione; Hypercholesterolemia; Hypertension; Kidney; Lipids; Losartan; Male; Malondialdehyde; Nitric Oxide Synthase Type III; Nitrites; Plant Extracts; Protective Agents; Rats, Wistar; Simvastatin; Systole; Urea | 2017 |
Candesartan, rather than losartan, improves motor dysfunction in thioacetamide-induced chronic liver failure in rats.
Topics: Alanine Transaminase; Ammonia; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Disease Models, Animal; End Stage Liver Disease; Enzyme-Linked Immunosorbent Assay; gamma-Glutamyltransferase; Glutathione; Liver; Liver Cirrhosis; Locomotion; Losartan; Male; Malondialdehyde; Motor Disorders; Random Allocation; Rats, Sprague-Dawley; Reproducibility of Results; Reverse Transcriptase Polymerase Chain Reaction; Tetrazoles; Thioacetamide; Treatment Outcome; Tumor Necrosis Factor-alpha | 2017 |
Protective effect of the standardized leaf extract of Ginkgo biloba (EGb761) against hypertension-induced renal injury in rats.
Topics: Animals; Antihypertensive Agents; Arterial Pressure; Cardiovascular Agents; Ginkgo biloba; Glutathione; Hypertension; Hypertension, Renal; Interleukin-1beta; Interleukin-6; Kidney; Kidney Diseases; Losartan; Male; Malondialdehyde; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Oxidative Stress; Plant Extracts; Rats; Tumor Necrosis Factor-alpha | 2018 |
Nigella sativa extract is a potent therapeutic agent for renal inflammation, apoptosis, and oxidative stress in a rat model of unilateral ureteral obstruction.
Topics: Angiotensin II; Animals; Apoptosis; Captopril; Chemokine CCL2; Creatinine; Fibrosis; Inflammation; Kidney; Kidney Diseases; Losartan; Male; Malondialdehyde; Nigella sativa; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Urea; Ureteral Obstruction | 2018 |
Protective effects of vitamin D and losartan in complete Freund's adjuvant-induced arthritis in rats.
Topics: Animals; Arthritis, Experimental; Blood Sedimentation; Cholesterol; Female; Freund's Adjuvant; Interleukin-6; Leukocyte Count; Losartan; Malondialdehyde; Protective Agents; Rats, Wistar; Tumor Necrosis Factor-alpha; Vitamin D | 2019 |
Dexamethasone and losartan combination treatment protected cigarette smoke-induced COPD in rats.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Bronchoalveolar Lavage Fluid; C-Reactive Protein; Cell Count; Dexamethasone; Drug Therapy, Combination; Intercellular Adhesion Molecule-1; Losartan; Lung; Male; Malondialdehyde; Matrix Metalloproteinase 9; NF-kappa B; Nicotiana; Oxidative Stress; Pulmonary Disease, Chronic Obstructive; Rats, Sprague-Dawley; Smoke; Superoxide Dismutase | 2021 |
Therapeutic effects of losartan on prostatic hyperplasia in spontaneously hypertensive rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Hypertension; Losartan; Male; Malondialdehyde; Oxidative Stress; Prostatic Hyperplasia; Rats; Rats, Inbred SHR; Rats, Inbred WKY | 2021 |