losartan and indomethacin

losartan has been researched along with indomethacin in 72 studies

Research

Studies (72)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's21 (29.17)18.2507
2000's33 (45.83)29.6817
2010's17 (23.61)24.3611
2020's1 (1.39)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
Avdeef, A; Tam, KY1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Barton, P; Luker, T; Wenlock, MC1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ1
Giacomini, KM; Huang, Y; Khuri, N; Kido, Y; Kosaka, A; Morrissey, KM; Sali, A; Wittwer, MB; Zhang, X; Zur, AA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Clozel, JP; Fischli, W; Hess, P; Véniant, M1
Harris, PJ; Mendelsohn, FA; Nobes, MS; Yamada, H1
Cachofeiro, V; Lahera, V; Maeso, R; Navarro, J; Rodrigo, E; Ruilope, LM1
Hamann, M; Hegyi, I; Kaissling, B; Kurtz, A; Schricker, K1
Abe, Y; Aki, Y; Kimura, S; Takenaka, I; Tamaki, T; Yoshida, H1
Hodgson, WC; Hopkins, BJ; Sutherland, SK1
Hajj-Ali, AF; Wong, PC1
Couch, SJ; Pals, DT1
Hollenberg, MD; Laniyonu, A; Saifeddine, M; Yang, SG1
Barthelmebs, M; Grima, M; Imbs, JL1
Alt-Tebacher, M; Barthelmebs, M; Grima, M; Imbs, JL; Madonna, O1
Chai, SK; Sim, MK1
Deck, CC; Gaballa, MA; Raya, TE1
Cox, SL; Story, DF; Ziogas, J1
Bolla, BS; de Guzman, FQ; Hussain, Y; Igić, R; Montiague, RR; Rabito, SF; Rajani, V1
Baan, J; Chang, PC; Pfaffendorf, M; van Zwieten, PA; Vermeij, P1
Hempelmann, RG; Mehdorn, HM; Pradel, RH; Ziegler, A1
Kadekaro, M; Liu, H; Summy-Long, JY; Terrell, ML1
Dige-Petersen, H; Hassager, C; Ibsen, H; Olsen, ME; Thomsen, T1
Ardaillou, R; Chansel, D; Henrion, D; Levy, BI; Loufrani, L1
Bessard, G; Chavanon, O; Devillier, P; Sessa, C; Stanke-Labesque, F; Tripodi, F1
Bischoff, A; Michel, MC1
Andersen, S; Bos, H; De Jong, PE; De Zeeuw, D; Navis, G; Parving, HH; Rossing, P1
Escalante, B; López-Sánchez, P; Martínez-Ayala, S; Rios, A; Sánchez-Mendoza, A; Vázquez-Cruz, B1
Arroyo, V; Bataller, R; Bosch, J; Garcia-Ramallo, E; Gasull, X; Ginès, P; Görbig, MN; Nicolás, JM; Rodés, J1
Jagroop, IA; Mikhailidis, DP1
Bui, V; Kadekaro, M; Liu, H; Summy-Long, JY; Terrell, ML1
Barr, E; Conlin, PR; DeLucca, P; Demopoulos, L; Fletcher, C; Gazdick, L; Moore, TJ; Swartz, SL1
Min, L; Sim, MK; Xu, XG1
Bui, V; Kadekaro, M; Summy-Long, JY; Terrell, ML1
Buczko, W; Chabielska, E; Kucharewicz, I; Matys, T; Pawlak, R1
Biggi, A; Carra, N; Dall'aglio, P; Montanari, A; Novarini, A; Orrico, A; Perinotto, P; Valmadre, G1
Bautista, R; Escalante, B; Hernández, J; Oyekan, A; Sánchez, A1
Kadekaro, M; Kershenovich, A; Summy-Long, JY; Terrell, ML1
Díez-Marqués, ML; Griera-Merino, M; Pérez-Rivero, G; Rodríguez-Puyol, D; Rodríguez-Puyol, M; Ruiz-Torres, MP1
Berg, T1
Buikema, H; de Zeeuw, D; Gschwend, S; Henning, RH; Pinto, YM; van Gilst, WH1
Kadekaro, M; Salas, N; Summy-Long, JY; Terrell, ML1
Crozier, S; Endre, ZH; Gobe, G; Guan, Z; Manley, SW; Matthias, A; Willgoss, DA1
Bäcker, A; Heller, J; Horacek, V; Kramer, HJ; Vaneckova, I1
Drenjancevic-Peric, I; Frisbee, JC; Lombard, JH; Phillips, SA1
Bennett, T; Davenport, AP; Gardiner, SM; Kemp, PA; March, JE; Wiley, KE1
Bennett, T; Gardiner, SM; Kemp, PA; March, JE1
Alenina, N; Almeida, AP; Bader, M; Castro, CH; Ferreira, AJ; Santos, RA1
Caron, N; Flamion, B; Imig, JD; Joly, E; Kramp, R; Michel, A; Seqqat, R1
Handa, RK1
Cesolari, JA; Laudanno, OM1
Gironacci, MM; Peña, C; Polizio, AH; Tomaro, ML1
Carstens, J; Pedersen, EB1
Badzynska, B; Sadowski, J1
Gardiner, P; Paine, SW1
Lee, KO; Sim, MK; Wong, YC1
de Oliveira Faria, T; Furieri, LB; Lizardo, JH; Padilha, AS; Silveira, EA; Siman, FD; Stefanon, I; Vassallo, DV; Vescovi, MV1
Brzozowski, T; Konturek, SJ; Korbut, R; Kwiecien, S; Madej, J; Olszanecki, R; Pajdo, R; Pawlik, MW; Ptak-Belowska, A; Suski, M; Targosz, A1
El-Din, MM; El-Mas, MM; Elmallah, AI; Khedr, MM; Nasser, SA; Sabra, R1
Costa, G; Dantas, AP; Garabito, M; Jiménez-Altayó, F; Onetti, Y; Sabate, M; Vila, E1
Alonso, MJ; Fioresi, M; Salaices, M; Simões, MR; Toscano, CM; Vassallo, DV1

Reviews

2 review(s) available for losartan and indomethacin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

5 trial(s) available for losartan and indomethacin

ArticleYear
Influence of indomethacin and L-NMMA on vascular tone and angiotensin II-induced vasoconstriction in the human forearm.
    Blood pressure, 1997, Volume: 6, Issue:5

    Topics: Adult; Angiotensin II; Antihypertensive Agents; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Forearm; Humans; Indomethacin; Losartan; Male; omega-N-Methylarginine; Regional Blood Flow; Vasoconstriction; Vasoconstrictor Agents; Vasomotor System

1997
Hemodynamic and renal effects of indomethacin in losartan-treated hypertensive individuals.
    American journal of hypertension, 1999, Volume: 12, Issue:2 Pt 1

    Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Hemodynamics; Humans; Hypertension; Indomethacin; Kidney; Kidney Function Tests; Losartan; Male; Middle Aged; Sodium; Treatment Outcome

1999
Effect of indomethacin on blood pressure lowering by captopril and losartan in hypertensive patients.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:3

    Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Captopril; Cardiovascular Agents; Circadian Rhythm; Drug Interactions; Female; Humans; Indomethacin; Losartan; Male; Middle Aged

2000
Angiotensin II and prostaglandin interactions on systemic and renal effects of L-NAME in humans.
    Journal of the American Society of Nephrology : JASN, 2001, Volume: 12, Issue:8

    Topics: Adult; Angiotensin II; Blood Pressure; Cyclooxygenase Inhibitors; Drug Synergism; Enzyme Inhibitors; Female; Humans; Indomethacin; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Prostaglandins; Renal Circulation; Sodium; Vasoconstriction

2001
Renal effects of urodilatin in healthy subjects are independent of blockade of the cyclooxygenase and angiotensin II receptor.
    Scandinavian journal of clinical and laboratory investigation, 2008, Volume: 68, Issue:1

    Topics: Adult; Aldosterone; Angiotensin Receptor Antagonists; Atrial Natriuretic Factor; Blood Pressure; Cross-Over Studies; Cyclic GMP; Diuresis; Diuretics; Glomerular Filtration Rate; Heart Rate; Hematocrit; Humans; Indomethacin; Kidney; Kidney Function Tests; Lithium; Losartan; Male; Natriuresis; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Receptors, Angiotensin; Renal Plasma Flow, Effective; Renin; Single-Blind Method

2008

Other Studies

65 other study(ies) available for losartan and indomethacin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
How well can the Caco-2/Madin-Darby canine kidney models predict effective human jejunal permeability?
    Journal of medicinal chemistry, 2010, May-13, Volume: 53, Issue:9

    Topics: Animals; Disease Models, Animal; Dogs; Humans; Jejunal Diseases; Kidney Diseases; Models, Biological; Permeability; Porosity; Regression Analysis

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Lipophilicity of acidic compounds: impact of ion pair partitioning on drug design.
    Bioorganic & medicinal chemistry letters, 2011, Jun-15, Volume: 21, Issue:12

    Topics: Acids; Albumins; Drug Design; Humans; Hydrogen-Ion Concentration; Lipids; Molecular Structure; Pharmaceutical Preparations; Protein Binding

2011
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
    Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship

2012
Discovery of potent, selective multidrug and toxin extrusion transporter 1 (MATE1, SLC47A1) inhibitors through prescription drug profiling and computational modeling.
    Journal of medicinal chemistry, 2013, Feb-14, Volume: 56, Issue:3

    Topics: Computer Simulation; Fluorescent Dyes; Organic Cation Transport Proteins; Prescription Drugs

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Effects of renin-angiotensin system blockade in guinea pigs.
    Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:3

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Cilazapril; Cyclooxygenase Inhibitors; Disease Models, Animal; Furosemide; Guinea Pigs; Hypertension; Imidazoles; Indomethacin; Losartan; Nephrectomy; Oligopeptides; Pyridazines; Renin; Renin-Angiotensin System; Tetrazoles

1992
Effects of angiotensin on renal cortical and papillary blood flows measured by laser-Doppler flowmetry.
    The American journal of physiology, 1991, Volume: 261, Issue:6 Pt 2

    Topics: Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Aorta; Aprotinin; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Constriction; Dose-Response Relationship, Drug; Imidazoles; Indomethacin; Kidney Cortex; Kidney Medulla; Lasers; Losartan; Male; Rats; Rats, Inbred WKY; Tetrazoles

1991
Nitric oxide and prostaglandins in the prolonged effects of losartan and ramipril in hypertension.
    Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:2

    Topics: Animals; Antihypertensive Agents; Arginine; Biphenyl Compounds; Blood Pressure; Bradykinin; Drug Interactions; Hypertension; Imidazoles; Indomethacin; Kidney Function Tests; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Ramipril; Rats; Rats, Inbred SHR; Tetrazoles

1995
Tonic stimulation of renin gene expression by nitric oxide is counteracted by tonic inhibition through angiotensin II.
    Proceedings of the National Academy of Sciences of the United States of America, 1995, Aug-15, Volume: 92, Issue:17

    Topics: Analysis of Variance; Angiotensin II; Animals; Arginine; Biphenyl Compounds; Enzyme Precursors; Enzyme Repression; Gene Expression Regulation, Enzymologic; Imidazoles; Indomethacin; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Ramipril; Rats; Rats, Sprague-Dawley; Renin; RNA, Messenger; Tetrazoles

1995
Effects of angiotensin II on isolated rabbit afferent arterioles.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:4

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arterioles; Aspirin; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Lysine; Male; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Antagonists; Prostaglandins; Rabbits; Renal Circulation; Tetrazoles; Vascular Resistance

1994
Pharmacological studies of stonefish (Synanceja trachynis) venom.
    Toxicon : official journal of the International Society on Toxinology, 1994, Volume: 32, Issue:10

    Topics: Animals; Biphenyl Compounds; Blood Pressure; Captopril; Chromones; Dose-Response Relationship, Drug; Fish Venoms; Fishes; Guinea Pigs; Heptanoic Acids; Histamine; Ileum; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Receptors, Thromboxane; Serotonin; SRS-A; Tetrazoles; Vas Deferens

1994
Beta adrenoceptor blockade in rabbit inhibits the renin-releasing effect of AT1 receptor antagonist losartan.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 267, Issue:3

    Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Atenolol; Biphenyl Compounds; Blood Pressure; Heart Rate; Imidazoles; Indomethacin; Losartan; Male; Rabbits; Renin; Tetrazoles

1993
Renin release induced by losartan (DuP 753), an angiotensin II receptor antagonist.
    Clinical and experimental hypertension (New York, N.Y. : 1993), 1993, Volume: 15, Issue:1

    Topics: Angiotensin Receptor Antagonists; Animals; Atenolol; Biphenyl Compounds; Dose-Response Relationship, Drug; Feedback; Imidazoles; Indomethacin; Injections, Intravenous; Losartan; Male; Meclofenamic Acid; Propranolol; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, beta; Receptors, Angiotensin; Renin; Sympathetic Nervous System; Tetrazoles

1993
Distinct signal transduction pathways for angiotensin-II in guinea pig gastric smooth muscle: differential blockade by indomethacin and tyrosine kinase inhibitors.
    The Journal of pharmacology and experimental therapeutics, 1993, Volume: 264, Issue:2

    Topics: Angiotensin II; Animals; Biphenyl Compounds; Calcium; Catechols; Cyclohexanones; Dose-Response Relationship, Drug; Epidermal Growth Factor; Genistein; Guinea Pigs; Imidazoles; In Vitro Techniques; Indoles; Indomethacin; Isoflavones; Losartan; Male; Muscle, Smooth; Nitriles; Protein-Tyrosine Kinases; Pyridines; Quinacrine; Signal Transduction; Stomach; Tetrazoles; Tyrphostins

1993
Ramipril-induced decrease in renal lithium excretion in the rat.
    British journal of pharmacology, 1995, Volume: 116, Issue:4

    Topics: Angiotensin I; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Biphenyl Compounds; Blood Pressure; Creatinine; Imidazoles; Indomethacin; Kidney; Lithium; Losartan; Male; Ramipril; Rats; Rats, Wistar; Tetrazoles

1995
Absence of a losartan interaction with renal lithium excretion in the rat.
    British journal of pharmacology, 1995, Volume: 116, Issue:4

    Topics: Angiotensin I; Angiotensin Receptor Antagonists; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Biphenyl Compounds; Creatinine; Diuresis; Imidazoles; Indomethacin; Kidney; Lithium; Losartan; Male; Rats; Rats, Wistar; Tetrazoles; Urodynamics; Water-Electrolyte Balance

1995
Subtypes of losartan-sensitive angiotensin receptor in the rabbit pulmonary artery.
    British journal of pharmacology, 1996, Volume: 117, Issue:7

    Topics: Angiotensin I; Animals; Antihypertensive Agents; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Muscle, Smooth, Vascular; Pulmonary Artery; Pyridines; Rabbits; Receptors, Angiotensin; Tetrazoles

1996
Relative contribution of angiotensin II, bradykinin, and prostaglandins to the renal effects of converting enzyme inhibition in rats after chronic myocardial infarction.
    Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:1

    Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cyclooxygenase Inhibitors; Hemodynamics; Imidazoles; Indomethacin; Kidney; Kidney Function Tests; Losartan; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Tetrazoles

1996
Multiple prejunctional actions of angiotensin II on noradrenergic transmission in the caudal artery of the rat.
    British journal of pharmacology, 1996, Volume: 119, Issue:5

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arteries; Biphenyl Compounds; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; NG-Nitroarginine Methyl Ester; Norepinephrine; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles; Vasoconstriction

1996
Attenuation of epinephrine-induced dysrhythmias by bradykinin: role of nitric oxide and prostaglandins.
    The American journal of cardiology, 1997, Aug-04, Volume: 80, Issue:3A

    Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biphenyl Compounds; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Epinephrine; Heart Rate; Imidazoles; Indomethacin; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Tetrazoles

1997
Contractions induced by NO synthase inhibition in isolated rat basilar artery: role of the endothelium and endogenous vasoconstrictors.
    Neurological research, 1998, Volume: 20, Issue:1

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Arginine Vasopressin; Basilar Artery; Carbachol; Endothelins; Endothelium, Vascular; Enzyme Inhibitors; Hormone Antagonists; Indomethacin; Ketanserin; Losartan; Male; Muscarinic Agonists; Nitric Oxide Synthase; Nitroarginine; Norepinephrine; Peptides, Cyclic; Periodicity; Rats; Rats, Sprague-Dawley; Serotonin; Serotonin Antagonists; Serotonin Receptor Agonists; Vasoconstriction; Vasoconstrictor Agents

1998
Brain ANG II and prostaglandins mediate the pressor response after central blockade of nitric oxide synthase.
    Brain research, 1998, Mar-02, Volume: 785, Issue:2

    Topics: Animals; Arginine; Blood Pressure; Cerebral Ventricles; Dose-Response Relationship, Drug; Heart Rate; Indomethacin; Injections, Intravenous; Injections, Intraventricular; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Prazosin; Rats; Rats, Sprague-Dawley

1998
Functional evidence for an angiotensin IV receptor in rat resistance arteries.
    The Journal of pharmacology and experimental therapeutics, 1999, Volume: 291, Issue:2

    Topics: Animals; Benzimidazoles; Biphenyl Compounds; Drug Interactions; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Perfusion; Phenylephrine; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Serotonin; Tachyphylaxis; Tetrazoles; Vascular Resistance

1999
Antagonistic effects of losartan on thromboxane A2-receptors in human isolated gastroepiploic artery and saphenous vein.
    Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:5

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Endothelin-1; Humans; In Vitro Techniques; Indomethacin; Losartan; Muscle Contraction; Muscle, Smooth, Vascular; Nitroarginine; Norepinephrine; Potassium Chloride; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Prostaglandin; Receptors, Thromboxane; Receptors, Thromboxane A2, Prostaglandin H2; Saphenous Vein; Serotonin; Stomach

1999
Neuropeptide Y enhances potassium excretion by mechanisms distinct from those controlling sodium excretion.
    Canadian journal of physiology and pharmacology, 2000, Volume: 78, Issue:2

    Topics: Aldosterone; Animals; Bradykinin; Humans; Indomethacin; Losartan; Male; Neuropeptide Y; Nifedipine; Potassium; Rats; Rats, Wistar; Sodium

2000
Role of patient factors in therapy resistance to antiproteinuric intervention in nondiabetic and diabetic nephropathy.
    Kidney international. Supplement, 2000, Volume: 75

    Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Diabetic Nephropathies; Enalapril; Humans; Indomethacin; Kidney Diseases; Lisinopril; Losartan; Proteinuria

2000
Angiotensin II modulates ion transport in rat proximal tubules through CYP metabolites.
    Biochemical and biophysical research communications, 2000, Jun-07, Volume: 272, Issue:2

    Topics: Adrenalectomy; Angiotensin II; Animals; Arachidonic Acid; Cyclooxygenase Inhibitors; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Dexamethasone; Dose-Response Relationship, Drug; Fatty Acids, Unsaturated; Hydroxyeicosatetraenoic Acids; Indomethacin; Ion Transport; Kidney Tubules, Proximal; Losartan; Male; Ouabain; Rats; Rats, Sprague-Dawley; Rubidium Radioisotopes

2000
Angiotensin II induces contraction and proliferation of human hepatic stellate cells.
    Gastroenterology, 2000, Volume: 118, Issue:6

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Cell Division; Cell Size; Cells, Cultured; Cyclooxygenase Inhibitors; Dinoprostone; Enzyme Inhibitors; Humans; Imidazoles; Indomethacin; Iodine Radioisotopes; Liver; Losartan; Mitogen-Activated Protein Kinases; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Penicillamine; Pyridines; Radioligand Assay; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sodium Nitrite; Thymidine; Vasoconstrictor Agents

2000
Angiotensin II can induce and potentiate shape change in human platelets: effect of losartan.
    Journal of human hypertension, 2000, Volume: 14, Issue:9

    Topics: Adenosine Diphosphate; Adult; Angiotensin II; Blood Platelets; Cell Size; Drug Synergism; Female; Humans; Indomethacin; Losartan; Male; Middle Aged; Serotonin

2000
Indomethacin prevents the L-NAME-induced increase in plasma levels of oxytocin in dehydrated rats.
    Brain research, 2000, Sep-22, Volume: 877, Issue:2

    Topics: Angiotensin II; Animals; Dehydration; Hypothalamo-Hypophyseal System; Indomethacin; Injections, Intraventricular; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Oxytocin; Prostaglandins; Rats; Rats, Sprague-Dawley; Vasopressins; Water Deprivation; Water-Electrolyte Balance

2000
Effects of des-aspartate-angiotensin I on angiotensin II-induced incorporation of phenylalanine and thymidine in cultured rat cardiomyocytes and aortic smooth muscle cells.
    Regulatory peptides, 2000, Nov-24, Volume: 95, Issue:1-3

    Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Aorta, Thoracic; Cells, Cultured; DNA; Imidazoles; Indomethacin; Losartan; Muscle, Smooth, Vascular; Myocardium; Peptide Fragments; Phenylalanine; Protein Biosynthesis; Pyridines; Rats; Rats, Wistar; Receptors, Angiotensin; Thymidine

2000
Central interactions between angiotensin II and PGD(2) in the regulation of vasopressin and oxytocin secretion in dehydrated rats.
    Brain research, 2001, Jan-19, Volume: 889, Issue:1-2

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Brain Chemistry; Central Nervous System; Cyclooxygenase Inhibitors; Dehydration; Indomethacin; Injections, Intraventricular; Losartan; Male; Oxytocin; Prostaglandin D2; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Vasoconstrictor Agents; Vasopressins

2001
Losartan inhibits the adhesion of rat platelets to fibrillar collagen--a potential role of nitric oxide and prostanoids.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2000, Volume: 51, Issue:4 Pt 1

    Topics: Animals; Antihypertensive Agents; Collagen; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Enzyme Inhibitors; In Vitro Techniques; Indomethacin; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Platelet Adhesiveness; Prostaglandins; Rats; Rats, Wistar

2000
Angiotensin II type AT(2) receptor mRNA expression and renal vasodilatation are increased in renal failure.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 38, Issue:3 Pt 2

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; 5,8,11,14-Eicosatetraynoic Acid; Angiotensin II; Animals; Antihypertensive Agents; Arachidonic Acid; Clotrimazole; Cytochrome P-450 Enzyme System; Dose-Response Relationship, Drug; Gene Expression Regulation; Imidazoles; In Vitro Techniques; Indomethacin; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Oligopeptides; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Insufficiency; RNA, Messenger; Vasodilation

2001
Angiotensin II does not mediate the pressor response to PGD2 (icv).
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2000, Volume: 1, Issue:2

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cyclooxygenase Inhibitors; Indomethacin; Injections, Intraventricular; Losartan; Male; Prostaglandin D2; Rats; Rats, Sprague-Dawley

2000
Angiotensin II induces a rapid and transient increase of reactive oxygen species.
    Antioxidants & redox signaling, 2002, Volume: 4, Issue:6

    Topics: Acrylates; Angiotensin II; Animals; Benzoates; Catalase; Cells, Cultured; Ditiocarb; Enzyme Inhibitors; Fluoresceins; Fluorescence; Hydrogen Peroxide; Indomethacin; Losartan; Muscle, Smooth, Vascular; NADH, NADPH Oxidoreductases; Onium Compounds; Pertussis Toxin; Phospholipases A; Phospholipases A2; Rats; Rats, Wistar; Reactive Oxygen Species

2002
The vascular response to the K+ channel inhibitor 4-aminopyridine in hypertensive rats.
    European journal of pharmacology, 2003, Apr-18, Volume: 466, Issue:3

    Topics: 4-Aminopyridine; Adrenalectomy; Adrenergic Antagonists; Amifampridine; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Endothelin Receptor Antagonists; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Indomethacin; Losartan; Male; Muscarinic Antagonists; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Phentolamine; Potassium Channel Blockers; Prazosin; Protein Kinase C; Pyrazines; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Endothelin A; Staurosporine; Sulfonamides; Vascular Resistance; Vasoconstriction

2003
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade.
    British journal of pharmacology, 2003, Volume: 139, Issue:7

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Captopril; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart; Heart Failure; Hydrazines; Imidazoles; Indomethacin; Lisinopril; Losartan; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Sympathetic Nervous System; Tetrazoles; Tetrodotoxin; Vascular Resistance

2003
Role of prostaglandin, endothelin and sympathetic nervous system on the L-NAME-induced pressor responses in spontaneously hypertensive rats.
    Brain research, 2003, Sep-05, Volume: 983, Issue:1-2

    Topics: Acetamides; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Chlorisondamine; Cyclooxygenase Inhibitors; Endothelin Receptor Antagonists; Endothelins; Enzyme Inhibitors; Ganglionic Blockers; Heart Rate; Indomethacin; Injections, Intraventricular; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type I; Oligopeptides; Prostaglandins; Rats; Rats, Inbred SHR; Sympathetic Nervous System

2003
Facilitation of renal autoregulation by angiotensin II is mediated through modulation of nitric oxide.
    Acta physiologica Scandinavica, 2003, Volume: 179, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cyclic N-Oxides; Endothelium-Dependent Relaxing Factors; Erythrocytes; Glomerular Filtration Rate; Homeostasis; Indomethacin; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Perfusion; Phenylephrine; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Sprague-Dawley; Spin Labels; Vasoconstriction

2003
Relative roles of nitric oxide, prostanoids and angiotensin II in the regulation of canine glomerular hemodynamics. A micropuncture study.
    Kidney & blood pressure research, 2004, Volume: 27, Issue:1

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclooxygenase Inhibitors; Dogs; Enzyme Inhibitors; Female; Glomerular Filtration Rate; Hemodynamics; Imidazoles; Indomethacin; Kidney Glomerulus; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Prostaglandins; Renal Circulation; Tetrazoles; Time Factors

2004
Chronic AT(1) receptor blockade alters mechanisms mediating responses to hypoxia in rat skeletal muscle resistance arteries.
    American journal of physiology. Heart and circulatory physiology, 2004, Volume: 287, Issue:2

    Topics: Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Cardiovascular Agents; Enzyme Inhibitors; Epoprostenol; Hypoxia; In Vitro Techniques; Indomethacin; Losartan; Male; Muscle, Skeletal; NG-Nitroarginine Methyl Ester; Oxygen; Partial Pressure; Rats; Rats, Sprague-Dawley; Receptors, Thromboxane A2, Prostaglandin H2; Thromboxane A2; Thromboxanes; Time Factors; Vascular Resistance; Vasoconstriction; Vasodilation; Vasodilator Agents

2004
Regional hemodynamic actions of selective corticotropin-releasing factor type 2 receptor ligands in conscious rats.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 312, Issue:1

    Topics: Animals; Corticotropin-Releasing Hormone; Drug Interactions; Hemodynamics; Indans; Indomethacin; Losartan; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Receptors, Corticotropin-Releasing Hormone; Urocortins

2005
Bolus injection of human UII in conscious rats evokes a biphasic haemodynamic response.
    British journal of pharmacology, 2004, Volume: 143, Issue:3

    Topics: Amidines; Animals; Arginine; Arginine Vasopressin; Benzylamines; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascular System; Consciousness; Enzyme Inhibitors; Heart Rate; Hemodynamics; Humans; Indans; Indomethacin; Injections, Intravenous; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Propranolol; Rats; Rats, Inbred F344; Rats, Inbred Lew; Rats, Inbred SHR; Rats, Inbred WKY; Rats, Sprague-Dawley; Urotensins; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2004
Evidence for a functional interaction of the angiotensin-(1-7) receptor Mas with AT1 and AT2 receptors in the mouse heart.
    Hypertension (Dallas, Tex. : 1979), 2005, Volume: 46, Issue:4

    Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Drug Synergism; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Myocardium; NG-Nitroarginine Methyl Ester; Peptide Fragments; Perfusion; Pressure; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Vasoconstrictor Agents

2005
Increased renal vascular reactivity to ANG II after unilateral nephrectomy in the rat involves 20-HETE.
    American journal of physiology. Regulatory, integrative and comparative physiology, 2006, Volume: 291, Issue:4

    Topics: Adaptation, Physiological; Amidines; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclooxygenase 1; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2J2; Cytochrome P-450 Enzyme System; Dinoprostone; Hydroxyeicosatetraenoic Acids; Imidazoles; Indomethacin; Losartan; Male; Microcirculation; Nephrectomy; Norepinephrine; Pyridines; Rats; Rats, Wistar; Renal Circulation; Vasoconstriction; Vasoconstrictor Agents

2006
Biphasic actions of angiotensin IV on renal blood flow in the rat.
    Regulatory peptides, 2006, Sep-11, Volume: 136, Issue:1-3

    Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Dose-Response Relationship, Drug; Imidazoles; Indomethacin; Kidney; Losartan; Male; Prostaglandin-Endoperoxide Synthases; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Regional Blood Flow; Vasodilator Agents

2006
[Angiotensin II AT1 receptor antagonists as antiinflammatory and gastric protection drugs].
    Acta gastroenterologica Latinoamericana, 2006, Volume: 36, Issue:2

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Inflammatory Agents; Benzimidazoles; Biphenyl Compounds; Carrageenan; Disease Models, Animal; Edema; Female; Gastric Mucosa; Indomethacin; Losartan; Rats; Rats, Wistar; Stomach Ulcer; Tetrazoles; Valine; Valsartan

2006
Angiotensin-(1-7) blocks the angiotensin II-stimulated superoxide production.
    Pharmacological research, 2007, Volume: 56, Issue:1

    Topics: Acetophenones; Allopurinol; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Drug Antagonism; Enzyme Inhibitors; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; NADH, NADPH Oxidoreductases; NG-Nitroarginine Methyl Ester; Onium Compounds; Peptide Fragments; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, G-Protein-Coupled; Superoxides

2007
Opposed effects of prostaglandin E2 on perfusion of rat renal cortex and medulla: interactions with the renin-angiotensin system.
    Experimental physiology, 2008, Volume: 93, Issue:12

    Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cyclooxygenase Inhibitors; Dinoprostone; Indomethacin; Infusions, Intra-Arterial; Kidney Cortex; Kidney Medulla; Laser-Doppler Flowmetry; Losartan; Male; Misoprostol; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Renal Artery; Renal Circulation; Renin-Angiotensin System; Ultrasonography; Vasoconstriction; Vasodilation

2008
The impact of hepatic uptake on the pharmacokinetics of organic anions.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:10

    Topics: Animals; Anions; Benzimidazoles; Benzoates; Bile Ducts; Dogs; Hepatocytes; Humans; Indomethacin; Liver; Losartan; Male; Models, Biological; Muscles; Organic Chemicals; Pharmaceutical Preparations; Protein Binding; Rats; Rats, Sprague-Dawley; Sulfisoxazole; Telmisartan; Tolmetin

2011
Des-aspartate-angiotensin-I and angiotensin IV improve glucose tolerance and insulin signalling in diet-induced hyperglycaemic mice.
    Biochemical pharmacology, 2011, Nov-01, Volume: 82, Issue:9

    Topics: Angiotensin I; Angiotensin II; Animals; Blood Glucose; Cystinyl Aminopeptidase; Dietary Fats; Dietary Sucrose; Drug Administration Schedule; Glucose Intolerance; Hyperglycemia; Indomethacin; Insulin; Insulin Receptor Substrate Proteins; Janus Kinase 2; Losartan; Male; Mice; Mice, Inbred C57BL; Phosphatidylinositol 3-Kinases; Receptor, Angiotensin, Type 1; Signal Transduction

2011
Low-dose chronic lead exposure increases systolic arterial pressure and vascular reactivity of rat aortas.
    Free radical biology & medicine, 2014, Volume: 67

    Topics: Acetophenones; Animals; Antioxidants; Aorta; Blood Pressure; Chronic Disease; Cyclooxygenase 2 Inhibitors; Indomethacin; Lead Poisoning; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Prostaglandins; Rats; Rats, Wistar; Renin-Angiotensin System; Superoxide Dismutase; Vascular Resistance; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents

2014
The renin-angiotensin system and its vasoactive metabolite angiotensin-(1-7) in the mechanism of the healing of preexisting gastric ulcers. The involvement of Mas receptors, nitric oxide, prostaglandins and proinflammatory cytokines.
    Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2016, Volume: 67, Issue:1

    Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cytokines; Enzyme Inhibitors; Gastric Mucosa; Imidazoles; Indomethacin; Interleukin-1beta; Lisinopril; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Stomach Ulcer; Superoxide Dismutase; Tumor Necrosis Factor-alpha

2016
Facilitation by the renin-angiotensin system of cyclosporine-evoked hypertension in rats: Role of arterial baroreflexes and vasoreactivity.
    Life sciences, 2016, Oct-15, Volume: 163

    Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II; Animals; Aorta; Atrasentan; Baroreflex; Blood Pressure; Captopril; Cyclosporine; Hypertension; Indomethacin; Losartan; Male; Naphthalenes; Nitric Oxide Synthase Type III; Nitroprusside; Oligopeptides; Phenylephrine; Piperidines; Propionates; Pyrrolidines; Rats; Renin-Angiotensin System; Vasoconstriction; Vasodilation

2016
Sex differences in angiotensin II responses contribute to a differential regulation of cox-mediated vascular dysfunction during aging.
    Experimental gerontology, 2016, 12-01, Volume: 85

    Topics: Aging; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Cyclooxygenase 2; Endothelium, Vascular; Female; Indomethacin; Losartan; Male; Mice; Oxidative Stress; Prostaglandins; Renin-Angiotensin System; Sex Factors; Vasodilation

2016
Sub-chronic lead exposure produces β
    Life sciences, 2017, Jul-01, Volume: 180

    Topics: Animals; Arterial Pressure; Cardiovascular Diseases; Down-Regulation; Heart Rate; Hexamethonium; Hypertension; Indomethacin; Isoproterenol; Lead; Losartan; Male; Nitric Oxide; Phenylephrine; Rats; Rats, Wistar; Receptors, Adrenergic, beta-1; Risk Factors

2017