losartan and icatibant

losartan has been researched along with icatibant in 53 studies

Research

Studies (53)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	35 (66.04)	18.2507
2000's	17 (32.08)	29.6817
2010's	1 (1.89)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Carretero, OA; Farhy, RD; Ho, KL; Scicli, AG	2
Clozel, JP; Fischli, W; Hess, P; Véniant, M	1
Chen, C; Lokhandwala, MF	1
Hartman, JC	1
Adamiak, D; Kregel, KC; Mott, A; Redlich, T; Stauss, HM; Unger, T; Zhu, YC	1
Cachofeiro, V; Lahera, V; Maeso, R; Navarro, J; Rodrigo, E; Ruilope, LM	1
Chen, C; Lokhandwala, MF; Sakamoto, T	1
Chen, K; Zimmerman, BG	1
Abeta, H; Asagami, T; Furukawa, L; Hino, T; Ishii, T; Kushiro, T; Otsuka, Y; Saito, F; Takahashi, A; Tomiyama, H	1
Hjemdahl, P; Kahan, T; Nussberger, J; Schwieler, JH	1
Chauvin, B; Giudicelli, JF; Richer, C	1
Elghozi, JL; Ponchon, P	2
Hérizi, A; Jover, B; Mimran, A	1
Duan, J; Fernandes, BH; Jaramillo, J; Jung, GL; Mathis, D; McLeod, AL	1
Cachofeiro, V; Casal, MC; Lahera, V; Maeso, R; Munoz-Garcia, R; Navarro, J; Rodrigo, E; Ruilope, LM	1
Amann, K; Gohlke, P; Kuwer, I; Mall, G; Schnell, A; Unger, T	1
Bolla, BS; de Guzman, FQ; Hussain, Y; Igić, R; Montiague, RR; Rabito, SF; Rajani, V	1
Berkenboom, G; Carpentier, Y; Fontaine, J; Grosfils, K; Langer, I	1
Gohlke, P; Pees, C; Unger, T	1
Chappell, MC; Ferrario, CM; Iyer, SN	1
Heller, J; Horácek, V; Kramer, HJ	1
Arnal, JF; Michel, JB; Pueyo, ME; Rami, J	1
Bischoff, A; Michel, MC; Rascher, W	1
Brown, NJ; Gainer, JV; King, DJ; Loveland, A; Morrow, JD	1
Demeilliers, B; Jover, B; Mimran, A	1
Anders, HJ; Ertl, G; Gaudron, P; Hu, K; Nahrendorf, M; Turschner, O; Weidemann, F	1
Angus, JA; Whorlow, SL; Wright, CE	1
Azizi, M	1
Dargie, HJ; Davie, AP; McMurray, JJ	1
Daihara, M; Kawahara, K; Nakagawa, H; Nozue, T; Tamakawa, H	1
Blair-West, JR; Harris, PJ; Rajaratne, AA; Walker, LL	1
Dukacz, SA; Kline, RL	1
Baldassarre, S; Berkenboom, G; Fontaine, D; Fontaine, J; Preumont, N; Unger, P	1
Gutierez, CI; Israel, A; Sosa, B	1
Bischoff, A; Michel, MC	1
Cierco, M; Israel, A; Sosa, B	1
Cierco, M; Gutierrez, CI; Israel, A; Sosa-Canache, B	1
Boegehold, MA; Nurkiewicz, TR	1
Das, DK; Deaton, DW; Engelman, RM; Flack, JE; Maulik, N; Otani, H; Rousou, JA; Sato, M	1
Fabiani, ME; Frauman, AG; Johnston, CI; Sourial, M; Thomas, WG	1
Giacca, A; Lapointe, N; Leung, N; Lewis, GF; Rouleau, JL; Szeto, L; Uffelman, KD; Wang, CH	1
Epelde, F; Heras, M; Pérez-Villa, F; Rigol, M; Roig, E; Roqué, M; Sanz, G; Solanes, N	1
Hiyoshi, H; Okamoto, H; Takano, M; Yayama, K	1
Alhenc-Gelas, F; Bergaya, S; Bloch-Faure, M; Boulanger, CM; Dong, Y; Hilgers, RH; Inagami, T; Lévy, BI; Meneton, P	1
Berti, F; Bianchi, M; Bonomo, S; De Gennaro Colonna, V; Ferrario, P; Fioretti, S; Manfredi, B; Muller, EE; Rigamonti, A; Rossoni, G	1
Berti, F; Bonomo, S; De Gennaro Colonna, V; Fioretti, S; Manfredi, B; Muller, EE; Rigamonti, A; Rossoni, G	1
Akimitsu, T; Akiyoshi, K; Hara, M; Saikawa, T; Yoshimatsu, H	1
Miyagi, R; Okamoto, H; Sugiyama, K; Yayama, K	1
Akira, T; Egi, Y; Maruyama, T; Matsumura, Y; Ohkita, M; Sasaoka, T; Takaoka, M; Tawa, M; Yamamoto, A	1
Costa, CA; Criddle, DN; Espinoza, LA; Marins de Carvalho, LC; Ognibene, DT; Oliveira, PR; Resende, AC; Soares de Moura, R; Tano, T	1
Bonde, MM; Erikstrup, N; Hansen, JL; Haunsø, S; Lyngsø, C; Nielsen, MS; Olsen, KB; Sheikh, SP; Speerschneider, T	1

Trials

2 trial(s) available for losartan and icatibant

Article	Year
Effect of bradykinin-receptor blockade on the response to angiotensin-converting-enzyme inhibitor in normotensive and hypertensive subjects. The New England journal of medicine, 1998, Oct-29, Volume: 339, Issue:18 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diet, Sodium-Restricted; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypertension; Kidney; Losartan; Male; Reference Values; Renin-Angiotensin System; Single-Blind Method	1998
Role of bradykinin in the vasodilator effects of losartan and enalapril in patients with heart failure. Circulation, 1999, Jul-20, Volume: 100, Issue:3 Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Cross-Over Studies; Double-Blind Method; Drug Interactions; Enalapril; Female; Heart Failure; Humans; Losartan; Male; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasodilator Agents	1999

Article

Year

Effect of bradykinin-receptor blockade on the response to angiotensin-converting-enzyme inhibitor in normotensive and hypertensive subjects.

The New England journal of medicine, 1998, Oct-29, Volume: 339, Issue:18

Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diet, Sodium-Restricted; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypertension; Kidney; Losartan; Male; Reference Values; Renin-Angiotensin System; Single-Blind Method

1998

Role of bradykinin in the vasodilator effects of losartan and enalapril in patients with heart failure.

Circulation, 1999, Jul-20, Volume: 100, Issue:3

Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Cross-Over Studies; Double-Blind Method; Drug Interactions; Enalapril; Female; Heart Failure; Humans; Losartan; Male; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasodilator Agents

1999

Other Studies

51 other study(ies) available for losartan and icatibant

Article	Year
Kinins mediate the antiproliferative effect of ramipril in rat carotid artery. Biochemical and biophysical research communications, 1992, Jan-15, Volume: 182, Issue:1 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Bridged Bicyclo Compounds; Carotid Arteries; Carotid Artery Injuries; Endothelium, Vascular; Imidazoles; Kinins; Losartan; Male; Muscle, Smooth, Vascular; Oligopeptides; Ramipril; Rats; Rats, Inbred Strains; Tetrazoles	1992
Effects of renin-angiotensin system blockade in guinea pigs. Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Cilazapril; Cyclooxygenase Inhibitors; Disease Models, Animal; Furosemide; Guinea Pigs; Hypertension; Imidazoles; Indomethacin; Losartan; Nephrectomy; Oligopeptides; Pyridazines; Renin; Renin-Angiotensin System; Tetrazoles	1992
Potentiation by enalaprilat of fenoldopam-evoked natriuresis is due to blockade of intrarenal production of angiotensin-II in rats. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:2 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Diuresis; Dopamine Agonists; Drug Synergism; Enalaprilat; Fenoldopam; Glomerular Filtration Rate; Imidazoles; Kidney; Losartan; Male; Natriuresis; Rats; Rats, Sprague-Dawley; Tetrazoles	1995
The role of bradykinin and nitric oxide in the cardioprotective action of ACE inhibitors. The Annals of thoracic surgery, 1995, Volume: 60, Issue:3 Topics: Adrenergic beta-Antagonists; Amino Acid Oxidoreductases; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Heart; Imidazoles; Losartan; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Ramipril; Receptors, Angiotensin; Receptors, Bradykinin; Tetrazoles	1995
Angiotensin-converting enzyme inhibition in infarct-induced heart failure in rats: bradykinin versus angiotensin II. Journal of cardiovascular risk, 1994, Volume: 1, Issue:3 Topics: Adrenergic beta-Antagonists; Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Disease Models, Animal; Heart; Heart Failure; Hemodynamics; Imidazoles; Isoquinolines; Losartan; Male; Myocardial Contraction; Myocardial Infarction; Myocardium; Organ Size; Rats; Rats, Wistar; Tetrahydroisoquinolines; Tetrazoles	1994
Nitric oxide and prostaglandins in the prolonged effects of losartan and ramipril in hypertension. Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:2 Topics: Animals; Antihypertensive Agents; Arginine; Biphenyl Compounds; Blood Pressure; Bradykinin; Drug Interactions; Hypertension; Imidazoles; Indomethacin; Kidney Function Tests; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Ramipril; Rats; Rats, Inbred SHR; Tetrazoles	1995
Role of kinins and nitric oxide in the effects of angiotensin converting enzyme inhibitors on neointima formation. Circulation research, 1993, Volume: 72, Issue:6 Topics: Amino Acid Oxidoreductases; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biphenyl Compounds; Bradykinin; Carotid Arteries; Imidazoles; Kinins; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Receptors, Neurotransmitter; Tetrazoles; Tunica Intima	1993
Contribution by bradykinin to the natriuretic response to the angiotensin converting enzyme inhibitor ramiprilat in spontaneously hypertensive rats. Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:1 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Glomerular Filtration Rate; Hemodynamics; Imidazoles; Losartan; Male; Natriuresis; Ramipril; Rats; Rats, Inbred SHR; Sodium; Tetrazoles	1994
Comparison of renal hemodynamic effect of ramiprilat to captopril; possible role of kinins. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:2 Topics: Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Imidazoles; Kidney; Kinins; Losartan; Male; Rabbits; Ramipril; Renal Circulation; Tetrazoles	1994
Kinins contribute to the improvement of insulin sensitivity during treatment with angiotensin converting enzyme inhibitor. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:4 Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Glucose; Blood Pressure; Body Weight; Bradykinin; Doxazosin; Enalapril; Glucose Clamp Technique; Hypertension; Imidazoles; Insulin; Kinins; Losartan; Male; Potassium; Rats; Rats, Inbred SHR; Sodium; Tetrazoles	1994
Converting enzyme inhibition modulates sympathetic neurotransmission in vivo via multiple mechanisms. The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Biphenyl Compounds; Blood Pressure; Bradykinin; Diclofenac; Dogs; Epinephrine; Female; Imidazoles; Losartan; Muscle Denervation; Muscles; Norepinephrine; Phenoxybenzamine; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles	1993
Lack of involvement of bradykinin in the vascular sympathoinhibitory effects of angiotensin converting enzyme inhibitors in spontaneously hypertensive rats. British journal of pharmacology, 1995, Volume: 116, Issue:4 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Decerebrate State; Hemodynamics; Hypertension; Imidazoles; Indoles; Losartan; Male; Muscle, Smooth, Vascular; Perindopril; Rats; Rats, Inbred SHR; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles; Vasoconstriction	1995
[Hormonal contribution to short-term variability of blood pressure in a renovascular hypertension model]. Archives des maladies du coeur et des vaisseaux, 1995, Volume: 88, Issue:8 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bradykinin; Disease Models, Animal; Heart Rate; Hypertension, Renovascular; Imidazoles; Kallikrein-Kinin System; Losartan; Male; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Signal Processing, Computer-Assisted; Tetrazoles	1995
Chronic kinin blockade and effect of ramipril in renal adaptation to sodium restriction. Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:1 Topics: Adaptation, Physiological; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Diet, Sodium-Restricted; Electrolytes; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Ramipril; Rats; Rats, Sprague-Dawley; Renal Circulation; Renin-Angiotensin System; Tetrazoles; Time Factors	1996
Comparative studies on differential inhibition of the renin - angiotensin system in the anesthetized guinea pig. Canadian journal of physiology and pharmacology, 1995, Volume: 73, Issue:10 Topics: Alanine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Guinea Pigs; Imidazoles; Losartan; Male; Nephrectomy; Pyridines; Renin; Renin-Angiotensin System; Tetrazoles; Thiazoles	1995
Contribution of the renin-angiotensin and kallikrein-kinin systems to short-term variability of blood pressure in two-kidney, one-clip hypertensive rats. European journal of pharmacology, 1996, Feb-15, Volume: 297, Issue:1-2 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Heart Rate; Hypertension, Renovascular; Imidazoles; Kallikrein-Kinin System; Losartan; Male; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Tetrazoles	1996
Acute renal excretory actions of losartan in spontaneously hypertensive rats: role of AT2 receptors, prostaglandins, kinins and nitric oxide. Journal of hypertension, 1995, Volume: 13, Issue:12 Pt 2 Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Bradykinin; Enzyme Inhibitors; Hemodynamics; Hypertension; Imidazoles; Infusions, Intravenous; Kidney; Kinins; Losartan; Male; Meclofenamic Acid; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Sodium; Tetrazoles	1995
Blockade of bradykinin B2 receptors prevents the increase in capillary density induced by chronic angiotensin-converting enzyme inhibitor treatment in stroke-prone spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:1 Pt 2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Capillaries; Coronary Vessels; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Losartan; Male; Neovascularization, Pathologic; Ramipril; Rats; Rats, Inbred SHR; Receptor, Bradykinin B2; Tetrazoles	1997
Attenuation of epinephrine-induced dysrhythmias by bradykinin: role of nitric oxide and prostaglandins. The American journal of cardiology, 1997, Aug-04, Volume: 80, Issue:3A Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biphenyl Compounds; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Epinephrine; Heart Rate; Imidazoles; Indomethacin; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Tetrazoles	1997
Ramipril prevents endothelial dysfunction induced by oxidized low-density lipoproteins: a bradykinin-dependent mechanism. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:3 Pt 1 Topics: Acetylcholine; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Endothelium, Vascular; Guanylate Cyclase; Lipoproteins, LDL; Losartan; Male; Nitric Oxide; Ramipril; Rats; Rats, Wistar; Vasodilation	1997
AT2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2 Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cerebrovascular Disorders; Cyclic GMP; Hypertension; Imidazoles; Losartan; Male; Minoxidil; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values	1998
Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2 Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Dipeptides; Heart Rate; Hypertension; Kinetics; Lisinopril; Losartan; Male; Neprilysin; Organophosphonates; Peptide Fragments; Peptides, Cyclic; Phenylalanine; Protease Inhibitors; Rats; Rats, Inbred SHR; Renin-Angiotensin System	1998
Comparative effects of the angiotensin II receptor blocker EXP 3174 and of the angiotensin-converting enzyme inhibitor captopril on renal glomerular hemodynamics in the dog. Kidney & blood pressure research, 1997, Volume: 20, Issue:6 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Blood Pressure; Bradykinin; Captopril; Dogs; Drug Combinations; Female; Glomerular Filtration Rate; Imidazoles; Kidney Glomerulus; Losartan; Male; Potassium; Sodium; Tetrazoles; Urea; Vascular Resistance; Vasodilation; Water	1997
Angiotensin II stimulates the production of NO and peroxynitrite in endothelial cells. The American journal of physiology, 1998, Volume: 274, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Arginine; Bradykinin; Calcium; Calmodulin; Cells, Cultured; Endothelium, Vascular; Losartan; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sulfonamides	1998
Bradykinin may be involved in neuropeptide Y-induced diuresis, natriuresis, and calciuresis. The American journal of physiology, 1998, Volume: 275, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Calcium; Creatinine; Denervation; Diuresis; Infusions, Intravenous; Kidney; Losartan; Male; Natriuresis; Neuropeptide Y; Ramipril; Rats; Rats, Wistar; Receptor, Bradykinin B2; Regional Blood Flow; Renal Circulation; Vascular Resistance	1998
Contrasting renal effects of chronic administrations of enalapril and losartan on one-kidney, one clip hypertensive rats. Journal of hypertension, 1998, Volume: 16, Issue:7 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Diet, Sodium-Restricted; Enalapril; Glomerular Filtration Rate; Hypertension, Renovascular; Kidney; Kinins; Losartan; Male; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium	1998
Chronic effects of early started angiotensin converting enzyme inhibition and angiotensin AT1-receptor subtype blockade in rats with myocardial infarction: role of bradykinin. Cardiovascular research, 1998, Volume: 39, Issue:2 Topics: Adrenergic beta-Antagonists; Analysis of Variance; Angiotensin I; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Dose-Response Relationship, Drug; Heart Ventricles; Hemodynamics; Hypertrophy, Left Ventricular; Isoquinolines; Losartan; Male; Myocardial Infarction; Organ Size; Quinapril; Rats; Rats, Wistar; Tetrahydroisoquinolines	1998
Endogenous angiotensin II and bradykinin delay and attenuate the hypotension after N-type calcium channel blockade in conscious rabbits. Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:6 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Bradykinin; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enalaprilat; Heart Rate; Hypotension; Losartan; Nasopharynx; omega-Conotoxin GVIA; Peptides; Pressoreceptors; Propranolol; Rabbits; Renin-Angiotensin System	1998
Bradykinin and inhibition of angiotensin-converting enzyme in hypertension. The New England journal of medicine, 1999, Mar-25, Volume: 340, Issue:12 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Drug Therapy, Combination; Humans; Hypertension; Losartan; Renin-Angiotensin System	1999
Effects of quinapril and losartan on insulin sensitivity in genetic hypertensive rats with different metabolic abnormalities. Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:1 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Chemical Analysis; Blood Pressure; Bradykinin; Drug Resistance; Drug Synergism; Glucose; Glucose Clamp Technique; Hypertension; Insulin; Isoquinolines; Losartan; Male; Quinapril; Rats; Rats, Inbred SHR; Tetrahydroisoquinolines	1999
The effects of angiotensin II on blood perfusion in the rat renal papilla. The Journal of physiology, 1999, Aug-15, Volume: 519 Pt 1 Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Kidney Medulla; Laser-Doppler Flowmetry; Losartan; Nitroarginine; Nitroprusside; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Regional Blood Flow; Renal Circulation; Ultrasonography	1999
Differing effects of enalapril and losartan on renal medullary blood flow and renal interstitial hydrostatic pressure in spontaneously hypertensive rats. Journal of hypertension, 1999, Volume: 17, Issue:9 Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Enalapril; Hydrostatic Pressure; Kidney Medulla; Laser-Doppler Flowmetry; Losartan; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation	1999
Absence of nitrate tolerance after long-term treatment with ramipril: an endothelium-dependent mechanism. Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:4 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Bradykinin; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Endothelium, Vascular; In Vitro Techniques; Losartan; Male; Nitrates; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Ramipril; Rats; Rats, Wistar; Superoxides; Time Factors; Vasodilator Agents	1999
Brain AT(2) receptor mediate vasodepressor response to footshocks: role of kinins and nitric oxide. Brain research bulletin, 2000, Mar-01, Volume: 51, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Brain; Electroshock; Enzyme Inhibitors; Extremities; Heart Rate; Imidazoles; Injections, Intraventricular; Losartan; Male; Nitric Oxide Synthase; Nitroarginine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Receptors, Angiotensin	2000
Neuropeptide Y enhances potassium excretion by mechanisms distinct from those controlling sodium excretion. Canadian journal of physiology and pharmacology, 2000, Volume: 78, Issue:2 Topics: Aldosterone; Animals; Bradykinin; Humans; Indomethacin; Losartan; Male; Neuropeptide Y; Nifedipine; Potassium; Rats; Rats, Wistar; Sodium	2000
Angiotensin AT(2) receptors mediate vasodepressor response to footshock in rats. Role of kinins, nitric oxide and prostaglandins. European journal of pharmacology, 2000, Apr-07, Volume: 394, Issue:1 Topics: Animals; Blood Pressure; Bradykinin; Electroshock; Heart Rate; Imidazoles; Kinins; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin	2000
Role of bradykinins and nitric oxide in the AT2 receptor-mediated hypotension. Journal of human hypertension, 2000, Volume: 14 Suppl 1 Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Drug Administration Routes; Enzyme Inhibitors; Hot Temperature; Hypertension; Hypotension; Imidazoles; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Shock; Vasodilation	2000
Reinforcement of arteriolar myogenic activity by endogenous ANG II: susceptibility to dietary salt. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Blood Pressure; Bradykinin; Diet, Sodium-Restricted; Losartan; Male; Microcirculation; Muscle, Skeletal; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Saralasin; Sodium, Dietary	2000
Myocardial protection by preconditioning of heart with losartan, an angiotensin II type 1-receptor blocker: implication of bradykinin-dependent and bradykinin-independent mechanisms. Circulation, 2000, Nov-07, Volume: 102, Issue:19 Suppl 3 Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensins; Animals; Apoptosis; Bradykinin; Bradykinin Receptor Antagonists; Heart; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Losartan; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Ventricular Function	2000
Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia. The Journal of endocrinology, 2001, Volume: 171, Issue:1 Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Norepinephrine; Oligopeptides; Prostate; Prostatic Hyperplasia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sympathetic Nervous System; Synaptic Transmission	2001
Vasopeptidase inhibitor omapatrilat induces profound insulin sensitization and increases myocardial glucose uptake in Zucker fatty rats: Studies comparing a vasopeptidase inhibitor, angiotensin-converting enzyme inhibitor, and angiotensin II type I recept Circulation, 2003, Apr-15, Volume: 107, Issue:14 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Transport; Blood Glucose; Bradykinin; Bradykinin Receptor Antagonists; Drug Synergism; Enzyme Inhibitors; Glucose; Glucose Clamp Technique; Insulin; Insulin Resistance; Losartan; Male; Myocardium; Neprilysin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Protease Inhibitors; Pyridines; Ramipril; Rats; Rats, Zucker; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B2; Thiazepines	2003
Enalaprilat, losartan and LU 135252 in coronary blood flow regulation. European journal of clinical investigation, 2003, Volume: 33, Issue:5 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bradykinin; Coronary Circulation; Enalaprilat; Female; Losartan; Male; Phenylpropionates; Pyrimidines; Swine	2003
Stimulation of cyclic GMP production via AT2 and B2 receptors in the pressure-overloaded aorta after banding. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:6 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Valve Stenosis; Bradykinin; Bradykinin B2 Receptor Antagonists; Cyclic GMP; Hypertension; Imidazoles; Ligation; Losartan; Male; Mice; Mice, Inbred ICR; Models, Animal; Nitric Oxide; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Renin; RNA, Messenger; Up-Regulation; Vasoconstriction	2004
Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors. Circulation research, 2004, Jun-25, Volume: 94, Issue:12 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Carotid Arteries; Hemorheology; Imidazoles; Losartan; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Pyridines; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Tetrazoles; Tissue Kallikreins; Vasodilation; Vasodilator Agents	2004
Angiotensin-converting enzyme inhibition and angiotensin AT1-receptor antagonism equally improve endothelial vasodilator function in L-NAME-induced hypertensive rats. European journal of pharmacology, 2005, Jun-15, Volume: 516, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Enalapril; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Systole; Vasoconstriction; Vasodilation; Vasodilator Agents	2005
Angiotensin II type 1 receptor antagonism improves endothelial vasodilator function in L-NAME-induced hypertensive rats by a kinin-dependent mechanism. Journal of hypertension, 2006, Volume: 24, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin B2 Receptor Antagonists; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Hypertension; Kinins; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Nitroprusside; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B2; RNA, Messenger; Vasodilation	2006
AT1 receptor blockade prevents microvascular dysfunction induced by ischemia/reperfusion injury. Journal of atherosclerosis and thrombosis, 2006, Volume: 13, Issue:5 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Bradykinin; Capillary Permeability; Cell Adhesion; Leukocyte Rolling; Leukocytes; Losartan; Male; Mesentery; Models, Animal; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Venules; Videotape Recording	2006
Angiotensin-converting enzyme inhibitor enhances liver regeneration following partial hepatectomy: involvement of bradykinin B2 and angiotensin AT1 receptors. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:3 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Bromodeoxyuridine; Dose-Response Relationship, Drug; Hepatectomy; Hepatocyte Growth Factor; Hepatocytes; Lisinopril; Liver Regeneration; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Time Factors	2007
Angiotensin II type 2 receptor-mediated inhibition of norepinephrine release in isolated rat hearts. Journal of cardiovascular pharmacology, 2008, Volume: 52, Issue:2 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bradykinin; Heart; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oligopeptides; Phenylalanine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System; Tranexamic Acid; Vasoconstrictor Agents	2008
Angiotensin II-mediated vasodilation is reduced in adult spontaneously hypertensive rats despite enhanced expression of AT2 receptors. Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:1 Topics: Acetylcholine; Aging; Angiotensin II; Animals; Blotting, Western; Bradykinin; Gene Expression Regulation; Imidazoles; Losartan; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Vasodilation	2009
The angiotensin II type 1 receptor antagonist Losartan binds and activates bradykinin B2 receptor signaling. Regulatory peptides, 2011, Feb-25, Volume: 167, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Chlorocebus aethiops; COS Cells; Hydrolysis; Kallikrein-Kinin System; Losartan; Myocardial Contraction; Phosphatidylinositols; Rats; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B2; Renin-Angiotensin System; Signal Transduction; Tetrazoles	2011