losartan has been researched along with gr 117289 in 7 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 6 (85.71) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dowle, MD; Hobson, JE; Jack, TI; Judd, DB; Middlemiss, D; Panchal, TA; Pass, M; Ross, BC; Scopes, DI; Tranquillini, E | 1 |
| Goldberg, MR; Greenlee, WJ; Irvin, JD; Prendergast, K; Smith, RD; Timmermans, PB; Wexler, RR | 1 |
| Giridhar, R; Murumkar, P; Naik, P; Yadav, MR | 1 |
| Barnes, JC; Clark, KL; Dowle, MD; Drew, GM; Marshall, FH; Michel, A; Middlemiss, D; Robertson, MJ; Ross, BC; Scopes, D | 1 |
| Barnes, JC; Clark, SA; Marshall, FH; Michel, AD | 1 |
| Baubonis, W; Benfield, P; Chiu, AT; Dunscomb, JH; McCall, DE; Sauer, B | 1 |
| Ciccocioppo, R; Cirillo, R; Massi, M; Polidori, C; Pompei, P | 1 |
2 review(s) available for losartan and gr 117289
| Article | Year |
|---|---|
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy.
Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Receptors, Angiotensin; Structure-Activity Relationship | 1996 |
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan | 2010 |
5 other study(ies) available for losartan and gr 117289
| Article | Year |
|---|---|
Bromobenzofuran-based non-peptide antagonists of angiotensin II: GR138950, a potent antihypertensive agent with high oral bioavailability.
Topics: Administration, Oral; Amino Acid Sequence; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzofurans; Biological Availability; Disease Models, Animal; Dogs; Hypertension; In Vitro Techniques; Kinetics; Molecular Sequence Data; Rabbits; Rats; Receptors, Angiotensin; Structure-Activity Relationship | 1994 |
Pharmacological profile of GR117289 in vitro: a novel, potent and specific non-peptide angiotensin AT1 receptor antagonist.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta; Binding Sites; Biphenyl Compounds; Cattle; Cerebellum; Dose-Response Relationship, Drug; Imidazoles; In Vitro Techniques; Liver; Losartan; Muscle Contraction; Muscle, Smooth, Vascular; Nicotinic Acids; Rabbits; Radioligand Assay; Receptors, Angiotensin; Tetrazoles; Vasoconstriction | 1992 |
Binding of angiotensin antagonists to rat liver and brain membranes measured ex vivo.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Blood-Brain Barrier; Brain; Imidazoles; In Vitro Techniques; Iodine Radioisotopes; Liver; Losartan; Male; Membranes; Nicotinic Acids; Pyridines; Rats; Receptors, Angiotensin; Saralasin; Tetrazoles | 1993 |
Characterization of angiotensin AT1A receptor isoform by its ligand binding signature.
Topics: Adrenal Cortex; Angiotensin I; Angiotensin III; Animals; Base Sequence; Binding, Competitive; Biphenyl Compounds; CHO Cells; Cricetinae; Guanosine 5'-O-(3-Thiotriphosphate); Imidazoles; Losartan; Molecular Sequence Data; Muscle, Smooth, Vascular; Nicotinic Acids; Pyridines; Rats; Receptors, Angiotensin; Recombinant Proteins; Saralasin; Tetrazoles; Transfection | 1993 |
Functional evidence for the ability of angiotensin AT1 receptor antagonists to cross the blood-brain barrier in rats.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Blood-Brain Barrier; Carbachol; Dose-Response Relationship, Drug; Drinking; Imidazoles; Injections, Intraperitoneal; Injections, Intraventricular; Losartan; Male; Nicotinic Acids; Pyrimidinones; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes | 1996 |