Compounds > losartan

losartan and glyburide

losartan has been researched along with glyburide in 16 studies

Research

Studies (16)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	1 (6.25)	18.2507
2000's	4 (25.00)	29.6817
2010's	8 (50.00)	24.3611
2020's	3 (18.75)	2.80

Authors

Authors	Studies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Andricopulo, AD; Moda, TL; Montanari, CA	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Barton, P; Luker, T; Wenlock, MC	1
Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ	1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Norman, BH	1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF	1
Bennett, T; Gardiner, SM; Kemp, PA; March, JE	1
Chang, HH; Chen, MF; Chen, PY; Chiang, CL; Kuo, JS; Lee, TJ; Lee, YC; Liu, CH; Yeh, JI	1
Abuohashish, HM; Ahmed, MM; Al-Rejaie, SS; Almnaizel, AT; Alotaibi, MR; Fatani, AJ	1
Ahante, E; Anachuna, KK; Asiwe, JN; Ben-Azu, B; Edje, KE; Eduviere, AT; Moke, EG; Oghoghovwe, IJ; Omogbai, EKI; Omogbiya, AI; Osagie-Eweka, SDE; Uchendu, AP; Umukoro, EK	1

Reviews

3 review(s) available for losartan and glyburide

Article	Year
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Drug Induced Liver Injury (DILI). Mechanisms and Medicinal Chemistry Avoidance/Mitigation Strategies. Journal of medicinal chemistry, 2020, 10-22, Volume: 63, Issue:20 Topics: Animals; Cell Line; Cell Survival; Chemical and Drug Induced Liver Injury; Drug Discovery; Drug Evaluation, Preclinical; Hepatocytes; Humans; Liver; Mitochondria, Liver; Pharmaceutical Preparations; Risk Assessment; Tissue Distribution	2020
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators. European journal of medicinal chemistry, 2022, Jul-05, Volume: 237 Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells	2022

Other Studies

13 other study(ies) available for losartan and glyburide

Article	Year
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
Hologram QSAR model for the prediction of human oral bioavailability. Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24 Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship	2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Lipophilicity of acidic compounds: impact of ion pair partitioning on drug design. Bioorganic & medicinal chemistry letters, 2011, Jun-15, Volume: 21, Issue:12 Topics: Acids; Albumins; Drug Design; Humans; Hydrogen-Ion Concentration; Lipids; Molecular Structure; Pharmaceutical Preparations; Protein Binding	2011
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification. Drug metabolism and disposition: the biological fate of chemicals, 2012, Volume: 40, Issue:12 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship	2012
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump. Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3 Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index	2014
Regional haemodynamic responses to infusion of lipopolysaccharide in conscious rats: effects of pre- or post-treatment with glibenclamide. British journal of pharmacology, 1999, Volume: 128, Issue:8 Topics: Animals; Antihypertensive Agents; Blood Pressure; Endothelin Receptor Antagonists; Glyburide; Heart Rate; Hemodynamics; Hindlimb; Hypoglycemic Agents; Indans; Lipopolysaccharides; Losartan; Male; Potassium Channel Blockers; Potassium Channels; Rats; Rats, Long-Evans; Renal Circulation; Vasodilation	1999
Role of perivascular adipose tissue-derived methyl palmitate in vascular tone regulation and pathogenesis of hypertension. Circulation, 2011, Sep-06, Volume: 124, Issue:10 Topics: 4-Aminopyridine; Adipocytes; Adipose Tissue; Angiotensin II; Animals; Aorta; Calcium; Cells, Cultured; Endothelium, Vascular; Fibroblasts; Glyburide; Hypertension; Losartan; Male; Palmitates; Peptides; Potassium Channels, Voltage-Gated; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetraethylammonium; Vasodilation; Vasodilator Agents	2011
In vivo Assessment of Combined Effects of Glibenclamide and Losartan in Diabetic Rats. Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2019, Volume: 28, Issue:2 Topics: Animals; Blood Glucose; Diabetes Mellitus, Experimental; Glutathione; Glutathione Peroxidase; Glutathione Reductase; Glyburide; Hypoglycemic Agents; Losartan; Oxidative Stress; Prospective Studies; Rats; Superoxide Dismutase	2019
Co-administration of metformin and/or glibenclamide with losartan reverse N Microvascular research, 2023, Volume: 147 Topics: Animals; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Experimental; Esters; Glyburide; Hypertension; Hypoglycemic Agents; Losartan; Metformin; NG-Nitroarginine Methyl Ester; Rats; Streptozocin; Water	2023