losartan has been researched along with gamma-aminobutyric acid in 12 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (33.33) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 2 (16.67) | 2.80 |
| Authors | Studies |
|---|---|
| Meanwell, NA | 1 |
| Foster, H; Foster, R; Philippou, H; Wilson, C | 1 |
| Harada, S; Hatta, T; Itoh, H; Kawa, T; Nakagawa, M; Nakata, T; Oguni, A; Sasaki, S; Takeda, K | 1 |
| Endo, S; Fukumori, R; Hagiwara, Y; Kubo, T | 1 |
| Chen, SR; Li, DP; Pan, HL | 1 |
| Hagiwara, Y; Kubo, T | 1 |
| Huber, DA; Schreihofer, AM | 1 |
| Czuczwar, SJ; Jakubus, T; Janowska, A; Lukawski, K; Raszewski, G | 1 |
| Kang, YM; Qi, J; Qin, DN; Su, Q; Suo, YP; Yang, Q; Yu, XJ; Yue, LY; Zhang, DM; Zhu, GQ | 1 |
| Jia, R; Liu, B; Liu, Q; Wang, T; Yu, H | 1 |
| Cao, T; Fan, Y; Hu, B; Jia, R; Lu, Y; Luo, X; Qiao, H; Sun, B; Wang, N; Yan, J | 1 |
| Bergamaschi, CT; Campos, RR; Milanez, MIO; Nishi, EE; Rocha, AA | 1 |
12 other study(ies) available for losartan and gamma-aminobutyric acid
| Article | Year |
|---|---|
Synopsis of some recent tactical application of bioisosteres in drug design.
Topics: Cytochrome P-450 Enzyme System; Drug Design | 2011 |
Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis.
Topics: Binding Sites; Biological Products; Humans; Ligands; Losartan; Molecular Dynamics Simulation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Signal Transduction; Small Molecule Libraries; Thrombosis | 2020 |
Role of the central nervous system in the development of hypertension produced by chronic nitric oxide blockade in rats.
Topics: Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Central Nervous System; Enzyme Inhibitors; gamma-Aminobutyric Acid; Hypertension; Losartan; Male; Microelectrodes; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Rats; Rats, Wistar; Renin-Angiotensin System | 2001 |
Activation of hypothalamic angiotensin receptors produces pressor responses via cholinergic inputs to the rostral ventrolateral medulla in normotensive and hypertensive rats.
Topics: Acetylcholine; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Carbachol; Cholinergic Agonists; Cholinergic Fibers; Cholinesterase Inhibitors; Electric Stimulation; gamma-Aminobutyric Acid; Hypertension; Hypothalamus, Anterior; Iontophoresis; Losartan; Male; Medulla Oblongata; Microinjections; Muscarinic Antagonists; Neural Pathways; Physostigmine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin; Scopolamine; Vasoconstrictor Agents | 2002 |
Angiotensin II stimulates spinally projecting paraventricular neurons through presynaptic disinhibition.
Topics: Action Potentials; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Excitatory Postsynaptic Potentials; Female; GABA Antagonists; gamma-Aminobutyric Acid; Imidazoles; Immunohistochemistry; In Vitro Techniques; Losartan; Male; Neural Inhibition; Neurons; Paraventricular Hypothalamic Nucleus; Patch-Clamp Techniques; Presynaptic Terminals; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Spinal Cord; Synaptophysin | 2003 |
Intracerebroventricular injection of losartan inhibits angiotensin II-sensitive neurons via GABA inputs in the anterior hypothalamic area of rats.
Topics: Action Potentials; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anterior Hypothalamic Nucleus; Bicuculline; GABA Antagonists; gamma-Aminobutyric Acid; Injections, Intraventricular; Losartan; Male; Microelectrodes; Neurons; Rats; Rats, Wistar | 2007 |
Altered regulation of the rostral ventrolateral medulla in hypertensive obese Zucker rats.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Brain Stem; Excitatory Amino Acid Antagonists; GABA Antagonists; gamma-Aminobutyric Acid; Glutamic Acid; Heart Rate; Hypertension; Losartan; Medulla Oblongata; Microinjections; Muscle Tonus; Muscle, Smooth, Vascular; Obesity; Rats; Rats, Zucker; Receptors, GABA-A; Splanchnic Circulation; Sympathetic Nervous System | 2011 |
Combined treatment with gabapentin and drugs affecting the renin-angiotensin system against electroconvulsions in mice.
Topics: Amines; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Anticonvulsants; Avoidance Learning; Benzimidazoles; Benzoates; Brain; Captopril; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroshock; Enalapril; Gabapentin; gamma-Aminobutyric Acid; Losartan; Male; Mice; Motor Skills; Seizures; Telmisartan | 2013 |
Chronic infusion of enalaprilat into hypothalamic paraventricular nucleus attenuates angiotensin II-induced hypertension and cardiac hypertrophy by restoring neurotransmitters and cytokines.
Topics: Angiotensin II; Animals; Cardiomegaly; Chemokine CCL2; Enalaprilat; gamma-Aminobutyric Acid; Glutamic Acid; Heart; Hypertension; Interleukin-10; Interleukin-1beta; Interleukin-6; Kidney; Losartan; Male; Neurotransmitter Agents; Norepinephrine; Organ Size; Paraventricular Hypothalamic Nucleus; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2014 |
Interaction between interleukin-1 beta and angiotensin II receptor 1 in hypothalamic paraventricular nucleus contributes to progression of heart failure.
Topics: Animals; Corticotropin-Releasing Hormone; Disease Models, Animal; Disease Progression; gamma-Aminobutyric Acid; Glutamic Acid; Heart Failure; Interleukin-1beta; Losartan; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1 | 2014 |
Angiotensin II facilitates GABAergic neurotransmission at postsynaptic sites in rat amygdala neurons.
Topics: Amygdala; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bicuculline; Electric Stimulation; Excitatory Amino Acid Agents; GABA Antagonists; GABAergic Neurons; gamma-Aminobutyric Acid; Imidazoles; In Vitro Techniques; Losartan; Male; Mice; Neurotransmitter Agents; Patch-Clamp Techniques; Pyridines; Rats; Rats, Sprague-Dawley; Synaptic Potentials; Vasoconstrictor Agents | 2018 |
Interaction between angiotensin II and GABA in the spinal cord regulates sympathetic vasomotor activity in Goldblatt hypertension.
Topics: Angiotensin II; Animals; Bicuculline; Blood Pressure; gamma-Aminobutyric Acid; Heart Rate; Hypertension, Renovascular; Losartan; Male; Rats, Wistar; Receptor, Angiotensin, Type 1; Spinal Cord; Sympathetic Nervous System | 2020 |