losartan has been researched along with fluorouracil in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 4 (26.67) | 29.6817 |
| 2010's | 8 (53.33) | 24.3611 |
| 2020's | 3 (20.00) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ | 1 |
| Ekins, S; Williams, AJ; Xu, JJ | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M | 1 |
| Babaoglu, MO; Boruban, C; Bozkurt, A; Coskun, U; Gunel, N; Gunes, A; Hassan, M; Rane, A; Sencan, O; Yasar, U; Zengil, H | 1 |
| Adstamongkonkul, P; Bawendi, MG; Boucher, Y; Chauhan, VP; Han, X; Huang, P; Jain, RK; Jain, SR; Kozin, SV; Lacorre, DA; Liu, H; Martin, JD; Mousa, AS; Popović, Z; Stylianopoulos, T | 1 |
| Allen, JN; Baglini, CV; Berger, DL; Blaszkowsky, LS; Boucher, Y; Clark, JW; Corcoran, RB; DeLaney, TF; Drapek, LC; Duda, DG; Faris, JE; Fernández-Del Castillo, C; Ferrone, CR; Goyal, L; Hong, TS; Jain, RK; Jiang, W; Kwak, EL; Lillemoe, KD; Ly, L; Murphy, JE; Nipp, RD; Parikh, AR; Qadan, M; Ryan, DP; Talele, N; Ting, DT; Weekes, CD; Wo, JY; Yeap, BY; Zhu, AX | 1 |
| Das, M | 1 |
| Barra, PB; da Silva Martins Rebouças, C; de Araújo, AA; de Carvalho Leitão, RF; de Castro Brito, GA; de Medeiros, CACX; de Sales Mota, PCM; Figueiredo, JG; Guerra, GCB; Marques, VB; Oliveira, MMB; Ribeiro, SB | 1 |
| Boucher, Y; Clark, JW; Duda, DG; Fernandez-Del Castillo, C; Fukumura, D; Gu, L; Hong, TS; Jain, RK; Kumar, AS; Kumra, H; Mino-Kenudson, M; Pittet, MJ; Posada, JM; Rosario, SR; Ryan, DP; Subudhi, S; Talele, NP; Wo, JY | 1 |
1 review(s) available for losartan and fluorouracil
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
3 trial(s) available for losartan and fluorouracil
| Article | Year |
|---|---|
Inhibitory effect of 5-fluorouracil on cytochrome P450 2C9 activity in cancer patients.
Topics: Adult; Aged; Aged, 80 and over; Antimetabolites, Antineoplastic; Aryl Hydrocarbon Hydroxylases; Colorectal Neoplasms; Cytochrome P-450 CYP2C9; Female; Fluorouracil; Genotype; Humans; Imidazoles; Losartan; Male; Middle Aged; Oxidation-Reduction; Tetrazoles | 2006 |
Total Neoadjuvant Therapy With FOLFIRINOX in Combination With Losartan Followed by Chemoradiotherapy for Locally Advanced Pancreatic Cancer: A Phase 2 Clinical Trial.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Female; Fluorouracil; Humans; Irinotecan; Leucovorin; Losartan; Male; Middle Aged; Neoadjuvant Therapy; Oxaliplatin; Pancreatic Neoplasms; Treatment Outcome | 2019 |
Addition of Losartan to FOLFIRINOX and Chemoradiation Reduces Immunosuppression-Associated Genes, Tregs, and FOXP3+ Cancer Cells in Locally Advanced Pancreatic Cancer.
Topics: Antineoplastic Combined Chemotherapy Protocols; Fluorouracil; Forkhead Transcription Factors; Humans; Immunosuppression Therapy; Leucovorin; Losartan; Neoadjuvant Therapy; Pancreatic Neoplasms; Tumor Microenvironment | 2023 |
11 other study(ies) available for losartan and fluorouracil
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Developing structure-activity relationships for the prediction of hepatotoxicity.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes | 2010 |
A predictive ligand-based Bayesian model for human drug-induced liver injury.
Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands | 2010 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries | 2023 |
Angiotensin inhibition enhances drug delivery and potentiates chemotherapy by decompressing tumour blood vessels.
Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Antineoplastic Agents; Cell Hypoxia; Collagen; Connective Tissue Growth Factor; Drug Repositioning; Drug Synergism; Endothelin-1; Female; Fluorouracil; Gene Expression Regulation, Neoplastic; Humans; Hyaluronic Acid; Losartan; Mammary Neoplasms, Experimental; Mechanotransduction, Cellular; Mice; Pancreatic Neoplasms; Receptor, Angiotensin, Type 1; Stress, Mechanical; Stromal Cells; Transforming Growth Factor beta1 | 2013 |
Combined treatment for locally advanced pancreatic cancer.
Topics: Adenocarcinoma; Antihypertensive Agents; Antineoplastic Agents; Antineoplastic Combined Chemotherapy Protocols; Chemoradiotherapy; Drug Combinations; Fluorouracil; Humans; Irinotecan; Leucovorin; Losartan; Neoplasm Staging; Oxaliplatin; Pancreatic Neoplasms | 2019 |
Losartan improves intestinal mucositis induced by 5-fluorouracil in mice.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antimetabolites, Antineoplastic; Cytokines; Female; Fluorouracil; Inflammation; Intestinal Mucosa; Losartan; Mice; Mucositis; Oxidative Stress | 2021 |