losartan and fenofibrate

losartan has been researched along with fenofibrate in 20 studies

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (5.00)18.2507
2000's8 (40.00)29.6817
2010's9 (45.00)24.3611
2020's2 (10.00)2.80

Authors

AuthorsStudies
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Aleo, MD; Bonin, PD; Luo, Y; Potter, DM; Swiss, R; Will, Y1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Delabio, LC; Dutra, JP; Hembecker, M; Kita, DH; Moure, VR; Pereira, GDS; Scheiffer, G; Valdameri, G; Zattoni, IF1
Bairaktari, E; Elisaf, M; Siamopoulos, KC; Tsimichodimos, V1
Elisaf, MS; Milionis, HJ1
Bardin, T1
Fukuchi, M; Ka, T; Moriwaki, Y; Takahashi, S; Tsutsumi, Z; Yamamoto, T1
Daskalopoulou, SS; Elisaf, M; Mikhailidis, DP; Tzovaras, V1
Inokuchi, T; Ka, T; Moriwaki, Y; Takahashi, S; Tsutsumi, Z; Yamamoto, T1
Perez-Ruiz, F1
Gerster, JC1
Hisatome, I; Igawa, O; Ogino, K1
Bundrick, JB; Litin, SC1
Carmona, L; Herrero-Beites, AM; Perez-Ruiz, F1
Kirch, W; Saar, J1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1

Reviews

5 review(s) available for losartan and fenofibrate

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Targeting breast cancer resistance protein (BCRP/ABCG2): Functional inhibitors and expression modulators.
    European journal of medicinal chemistry, 2022, Jul-05, Volume: 237

    Topics: Antineoplastic Agents; ATP Binding Cassette Transporter, Subfamily G, Member 2; Breast Neoplasms; Drug Resistance, Multiple; Drug Resistance, Neoplasm; Female; Humans; Neoplasm Proteins; Neoplastic Stem Cells

2022
Effect on serum uric acid levels of drugs prescribed for indications other than treating hyperuricaemia.
    Current pharmaceutical design, 2005, Volume: 11, Issue:32

    Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Anti-Inflammatory Agents, Non-Steroidal; Atorvastatin; Fenofibrate; Heptanoic Acids; Humans; Losartan; Pyrroles; Uric Acid

2005
[Involvement of the foot in metabolic diseases].
    Praxis, 2007, Aug-22, Volume: 96, Issue:34

    Topics: Achilles Tendon; Acute Disease; Allopurinol; Anti-Inflammatory Agents, Non-Steroidal; Apatites; Chondrocalcinosis; Colchicine; Fenofibrate; Foot Diseases; Gout; Gout Suppressants; Hallux; Hemochromatosis; Humans; Hypercholesterolemia; Hyperostosis, Diffuse Idiopathic Skeletal; Hypolipidemic Agents; Losartan; Radiography; Renal Dialysis; Time Factors; Xanthomatosis

2007
[Other antihyperuricemic agents].
    Nihon rinsho. Japanese journal of clinical medicine, 2008, Volume: 66, Issue:4

    Topics: Antihypertensive Agents; Cardiovascular Diseases; Drug Therapy, Combination; Fenofibrate; Gout; Gout Suppressants; Humans; Hyperlipidemias; Hypertension; Hyperuricemia; Hypolipidemic Agents; Losartan; Uric Acid

2008

Trials

2 trial(s) available for losartan and fenofibrate

ArticleYear
Effects of combination treatment using anti-hyperuricaemic agents with fenofibrate and/or losartan on uric acid metabolism.
    Annals of the rheumatic diseases, 2003, Volume: 62, Issue:6

    Topics: Adult; Angiotensin Receptor Antagonists; Drug Therapy, Combination; Fenofibrate; Gout Suppressants; Humans; Hypertension; Hypertriglyceridemia; Hyperuricemia; Hypolipidemic Agents; Losartan; Male; Middle Aged

2003
Effects of a fenofibrate/losartan combination on the plasma concentration and urinary excretion of purine bases.
    International journal of clinical pharmacology and therapeutics, 2006, Volume: 44, Issue:1

    Topics: Adult; Antihypertensive Agents; Cholesterol; Dose-Response Relationship, Drug; Fenofibrate; Humans; Hypolipidemic Agents; Hypoxanthine; Losartan; Male; Metabolic Clearance Rate; Middle Aged; Time Factors; Triglycerides; Uric Acid; Xanthine

2006

Other Studies

13 other study(ies) available for losartan and fenofibrate

ArticleYear
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Human drug-induced liver injury severity is highly associated with dual inhibition of liver mitochondrial function and bile salt export pump.
    Hepatology (Baltimore, Md.), 2014, Volume: 60, Issue:3

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Chemical and Drug Induced Liver Injury; Humans; Male; Mitochondria, Liver; Rats; Rats, Sprague-Dawley; Severity of Illness Index

2014
Effect of micronized fenofibrate and losartan combination on uric acid metabolism in hypertensive patients with hyperuricemia.
    Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:1

    Topics: Adult; Aged; Antihypertensive Agents; Blood Chemical Analysis; Female; Fenofibrate; Humans; Hypertension; Hypolipidemic Agents; Losartan; Male; Middle Aged; Polypharmacy; Uric Acid

1999
Management of hypertension and dyslipidaemia in patients presenting with hyperuricaemia: case histories.
    Current medical research and opinion, 2000, Volume: 16, Issue:3

    Topics: Antihypertensive Agents; Arteriosclerosis; Benzothiadiazines; Diuretics; Female; Fenofibrate; Humans; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Losartan; Male; Middle Aged; Risk Factors; Sodium Chloride Symporter Inhibitors; Uric Acid

2000
Fenofibrate and losartan.
    Annals of the rheumatic diseases, 2003, Volume: 62, Issue:6

    Topics: Drug Therapy, Combination; Fenofibrate; Gout Suppressants; Humans; Hypertension; Hyperuricemia; Losartan

2003
New treatments for gout.
    Joint bone spine, 2007, Volume: 74, Issue:4

    Topics: Allopurinol; Ascorbic Acid; Female; Fenofibrate; Gout; Gout Suppressants; Humans; Losartan; Male; Sensitivity and Specificity; Urate Oxidase; Uric Acid

2007
Clinical pearls in general internal medicine.
    Mayo Clinic proceedings, 2011, Volume: 86, Issue:1

    Topics: Abdominal Pain; Adrenergic alpha-1 Receptor Antagonists; Adult; Aged; Androgen Antagonists; Anti-Infective Agents, Urinary; Antihypertensive Agents; Calcium Channel Blockers; Creatinine; Diagnosis, Differential; Female; Fenofibrate; Gout; Humans; Hypoglycemic Agents; Hypolipidemic Agents; Internal Medicine; Losartan; Male; Metformin; Nifedipine; Potassium; Sulfonamides; Tamsulosin; Trimethoprim; Ureteral Calculi; Vitamin B 12 Deficiency

2011
A two-stage approach to the treatment of hyperuricemia in gout: the "dirty dish" hypothesis.
    Arthritis and rheumatism, 2011, Volume: 63, Issue:12

    Topics: Aged; Cohort Studies; Colchicine; Crystallization; Female; Fenofibrate; Follow-Up Studies; Gout; Gout Suppressants; Humans; Hyperuricemia; Kaplan-Meier Estimate; Losartan; Male; Middle Aged; Prospective Studies; Regression Analysis; Secondary Prevention; Time Factors; Treatment Outcome; Uric Acid; Withholding Treatment

2011
[A new application for well-known pharmaceutics--losartan and fenofibrate as potential remedies against gout?].
    Deutsche medizinische Wochenschrift (1946), 2014, Volume: 139, Issue:12

    Topics: Angiotensin II Type 1 Receptor Blockers; Fenofibrate; Gout; Gout Suppressants; Humans; Hypolipidemic Agents; Losartan; Off-Label Use; Treatment Outcome; Uric Acid

2014
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023