losartan and exp-3179

losartan has been researched along with exp-3179 in 3 studies

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Aldrich, PE; Carini, DJ; Chiu, AT; Duncia, JV; Johnson, AL; Pierce, ME; Price, WA; Santella, JB; Wells, GJ; Wexler, RR1
Fukami, T; Hosomi, H; Iwamura, A; Nakajima, M; Yokoi, T1
Foster, H; Foster, R; Philippou, H; Wilson, C1

Other Studies

3 other study(ies) available for losartan and exp-3179

ArticleYear
Nonpeptide angiotensin II receptor antagonists: the discovery of a series of N-(biphenylylmethyl)imidazoles as potent, orally active antihypertensives.
    Journal of medicinal chemistry, 1991, Volume: 34, Issue:8

    Topics: Administration, Oral; Adrenal Glands; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Chemical Phenomena; Chemistry; Hypertension; Imidazoles; Losartan; Male; Molecular Structure; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Structure-Activity Relationship; Tetrazoles

1991
CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:5

    Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; HEK293 Cells; Hep G2 Cells; Hepatocytes; Humans; Losartan; NF-E2-Related Factor 2; Semicarbazides; Sensitivity and Specificity; Time Factors; Uricosuric Agents

2011
Progress toward a Glycoprotein VI Modulator for the Treatment of Thrombosis.
    Journal of medicinal chemistry, 2020, 11-12, Volume: 63, Issue:21

    Topics: Binding Sites; Biological Products; Humans; Ligands; Losartan; Molecular Dynamics Simulation; Platelet Aggregation Inhibitors; Platelet Membrane Glycoproteins; Protein Kinase Inhibitors; Signal Transduction; Small Molecule Libraries; Thrombosis

2020