losartan and eprosartan

losartan has been researched along with eprosartan in 56 studies

Research

Studies (56)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	13 (23.21)	18.2507
2000's	30 (53.57)	29.6817
2010's	9 (16.07)	24.3611
2020's	4 (7.14)	2.80

Authors

Authors	Studies
Goldberg, MR; Greenlee, WJ; Irvin, JD; Prendergast, K; Smith, RD; Timmermans, PB; Wexler, RR	1
Berellini, G; Cruciani, G; Mannhold, R	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Ekins, S; Williams, AJ; Xu, JJ	1
Giridhar, R; Murumkar, P; Naik, P; Yadav, MR	1
Fukami, T; Hosomi, H; Iwamura, A; Nakajima, M; Yokoi, T	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Benfield, P; Chiu, AT; Herblin, WF; Smith, RD; Timmermans, PB; Wong, PC	1
Brooks, DP; DePalma, PD; Ruffolo, RR	1
Brooks, DP; Edwards, RM; Gellai, M; Jugus, J; Ohlstein, EH; Ruffolo, RR; Sulpizio, A; Vickery, L; Weinstock, J	1
Aiyar, N; Edwards, RM; Hill, DT; Keenan, RM; Stack, EJ; Weidley, EF; Weinstock, J	1
Brooks, DP; Edwards, RM; Fredrickson, TA; Gellai, M; Ruffolo, RR; Weinstock, J	1
Bauer, JH; Reams, GP	1
Ganter, RC; Hondrelis, J; Matsoukas, J; Moore, DM; Moore, GJ; Smith, JR; Wahhab, A	1
Edwards, RM; Stack, EJ; Trizna, W; Weinstock, J	1
Blum, RA; Boike, SC; Etheredge, R; Ilson, B; Jorkasky, DK; Kazierad, DJ; Martin, DE; Tenero, DM	1
Brooks, DP; Feuerstein, GZ; Ohlstein, EH; Ruffolo, RR	1
Oparil, S	1
Chung, O; Csikós, T; Unger, T	1
DelGrande, D; Shetty, SS	1
Kiukaanniemi, K; Pelkonen, O; Taavitsainen, P	1
Grossman, E; Messerli, FH; Neutel, JM	1
Vidt, DG	1
Ramahi, TM	1
Guimarães, S; Loio, A; Moura, D; Pinheiro, H; Tavares, P	1
Giatas, N; Golic Grdadolnik, S; Iliodromitis, EK; Keivish, T; Kremastinos, DT; Matsoukas, J; Mavromoustakos, T; Mutule, I; Polevaya, L; Roumelioti, P; Vlahakos, DV; Zoumboulakis, P	1
Magometschnigg, D	1
Akesolo, U; Alonso, RM; González, L; Jiménez, RM	1
Rapi, J	1
Puig, JG; Ruilope, LM; Torres, R	1
Gurevich, MA	1
Mancini, GB	1
Krovat, EM; Langer, T	1
Schieffer, B; Schmidt, B	1
Terra, SG	1
Jermendy, G; Matos, L; Winkler, G	1
Dominiak, P; Häuser, W	1
Ivanova, NA; Preobrazhenskiĭ, DV; Sidorenko, BA; Soplevenko, AV; Stetsenko, TM	1
Clasen, R; Janke, J; Kintscher, U; Schupp, M; Unger, T	1
Hatzizacharias, A; Krespi, P; Makris, TK; Papadopoulos, DP; Stavroulakis, G; Tsoukala, C; Votteas, VE; Zilidis, A	1
Campbell, DJ; Esler, MD; Krum, H	1
Dendorfer, A; Dominiak, P; Raasch, W; Tempel, K	1
Campbell, DJ; Esler, M; Krum, H; Lambert, E; Windebank, E	1
Cierco, M; del Rosario Garrido, M; Gutierrez, A; Israel, A; Zavala, LE	1
Cierco, M; Garrido, MR; Gutiérrez, A; Israel, A; Zavala, LE	1
Aulakh, GK; Singh, M; Sodhi, RK	1
Benndorf, RA; Böger, RH; Divac, N; Haefeli, WE; Herzog, M; Sauer, A; Schwedhelm, E; Weiss, J	1
Ambrosioni, E; Bombelli, M; Cerasola, G; Cipollone, F; Ferri, C; Grazioli, I; Leprotti, C; Mancia, G; Melzi, G; Mugellini, A; Mulè, G; Palasciano, G; Salvetti, A; Trimarco, B	1
Ah, YM; Choi, KH; Choi, YJ; Han, N; Kim, B; Kong, J; Lee, HY; Lee, JY; Oh, JM; Shin, WG; Yu, YM	1
Abdelsalam, RA; Haddad, GM; Marghany, KA	1
Majer, J; Masajtis-Zagajewska, A; Nowicki, M	1
Berto-Junior, C; Guimarães-Nobre, CC; Mendonça-Reis, E; Miranda-Alves, L; Teixeira-Alves, LR	1

Reviews

16 review(s) available for losartan and eprosartan

Article	Year
Nonpeptide angiotensin II receptor antagonists: the next generation in antihypertensive therapy. Journal of medicinal chemistry, 1996, Feb-02, Volume: 39, Issue:3 Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Humans; Receptors, Angiotensin; Structure-Activity Relationship	1996
Angiotensin II receptor type 1 (AT1) selective nonpeptidic antagonists--a perspective. Bioorganic & medicinal chemistry, 2010, Dec-15, Volume: 18, Issue:24 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Humans; Losartan	2010
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
Angiotensin II receptors and functional correlates. American journal of hypertension, 1992, Volume: 5, Issue:12 Pt 2 Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Humans; Hypertension; Imidazoles; Losartan; Pyridines; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Thiophenes	1992
The angiotensin II type 1 receptor antagonists. A new class of antihypertensive drugs. Archives of internal medicine, 1995, Jul-10, Volume: 155, Issue:13 Topics: Acrylates; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Imidazoles; Irbesartan; Losartan; Pyridines; Quinolines; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan	1995
Angiotensin II receptor pharmacology and AT1-receptor blockers. Journal of human hypertension, 1999, Volume: 13 Suppl 1 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Thiophenes	1999
Angiotensin II receptor blockers: equal or preferred substitutes for ACE inhibitors? Archives of internal medicine, 2000, Jul-10, Volume: 160, Issue:13 Topics: Acrylates; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Therapy, Combination; Heart; Humans; Hypertension; Imidazoles; Irbesartan; Kidney; Losartan; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes	2000
Expanded role for ARBs in cardiovascular and renal disease? Recent observations have far-reaching implications. Postgraduate medicine, 2001, Volume: 109, Issue:4 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Cardiovascular Diseases; Humans; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Metabolic Clearance Rate; Patient Selection; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Treatment Outcome; Valine; Valsartan	2001
[Angiotensin receptor blockers--significance for the therapy of hypertension]. Wiener medizinische Wochenschrift (1946), 2001, Volume: 151, Issue:7-8 Topics: Acrylates; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Austria; Benzimidazoles; Benzoates; Biphenyl Compounds; Humans; Hypertension; Imidazoles; Losartan; Prodrugs; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Valine; Valsartan	2001
[Irbesartan: a new possibility in the treatment of hypertension]. Orvosi hetilap, 2002, May-26, Volume: 143, Issue:21 Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Biological Availability; Biphenyl Compounds; Controlled Clinical Trials as Topic; Drug Administration Schedule; Enalapril; Half-Life; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan	2002
[Policy of antihypertensive therapy in arterial hypertension in the elderly. II]. Klinicheskaia meditsina, 2002, Volume: 80, Issue:9 Topics: Acrylates; Adrenergic alpha-Antagonists; Age Factors; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzothiadiazines; Calcium Channel Blockers; Clinical Trials as Topic; Diuretics; Doxazosin; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Perindopril; Risk Factors; Sex Factors; Sodium Chloride Symporter Inhibitors; Thiophenes	2002
Emerging role of angiotensin II type 1 receptor blockers for the treatment of endothelial dysfunction and vascular inflammation. The Canadian journal of cardiology, 2002, Volume: 18, Issue:12 Topics: Acrylates; Aged; Antihypertensive Agents; Benzimidazoles; Biomarkers; Biphenyl Compounds; Coronary Artery Disease; Data Interpretation, Statistical; Diabetes Mellitus; E-Selectin; Endothelium, Vascular; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Tetrazoles; Thiophenes; Vasculitis	2002
Angiotensin II AT1 receptor antagonists. Clinical implications of active metabolites. Journal of medicinal chemistry, 2003, Jun-05, Volume: 46, Issue:12 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Growth Hormone; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Models, Molecular; Receptor, Angiotensin, Type 1; Tetrazoles; Thiophenes; Thromboxane A2	2003
[Theoretical background of angiotensin II receptor blockade and its features in clinical pharmacology]. Orvosi hetilap, 2003, Sep-07, Volume: 144, Issue:36 Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Humans; Imidazoles; Irbesartan; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan	2003
[Candesartan - a novel AT(1)-angiotensin receptor blocker: peculiarities of pharmacology and experience of use in arterial hypertension]. Kardiologiia, 2004, Volume: 44, Issue:1 Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Diabetic Nephropathies; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Tetrazoles; Thiophenes; Valine; Valsartan	2004
An update on non-peptide angiotensin receptor antagonists and related RAAS modulators. Life sciences, 2007, Aug-02, Volume: 81, Issue:8 Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Animals; Endothelin Receptor Antagonists; Humans; Hypertension; Imidazoles; Losartan; Protease Inhibitors; Receptors, Thromboxane A2, Prostaglandin H2; Renin; Renin-Angiotensin System; Thiophenes	2007

Trials

9 trial(s) available for losartan and eprosartan

Article	Year
Effect of fluconazole on the pharmacokinetics of eprosartan and losartan in healthy male volunteers. Clinical pharmacology and therapeutics, 1997, Volume: 62, Issue:4 Topics: Acrylates; Adult; Antifungal Agents; Antihypertensive Agents; Area Under Curve; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 Enzyme System; Drug Administration Schedule; Fluconazole; Humans; Imidazoles; Losartan; Male; Middle Aged; Reference Values; Steroid 16-alpha-Hydroxylase; Steroid Hydroxylases; Tetrazoles; Thiophenes; Time Factors	1997
AT1 blockers and uric acid metabolism: are there relevant differences? Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 2002, Volume: 20, Issue:5 Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Double-Blind Method; Humans; Hypertension; Imidazoles; Losartan; Receptor, Angiotensin, Type 1; Thiophenes; Uric Acid	2002
Eprosartan effect on fibrinolytic/hemostatic variables in arterial hypertension: a comparative study to losartan. Drugs under experimental and clinical research, 2004, Volume: 30, Issue:3 Topics: Acrylates; Aged; Angiotensin II Type 1 Receptor Blockers; Drug Administration Schedule; Female; Fibrinogen; Fibrinolysis; Follow-Up Studies; Hemostasis; Humans; Hypertension; Imidazoles; Lipoproteins; Losartan; Male; Middle Aged; Plasminogen Activator Inhibitor 1; Receptor, Angiotensin, Type 1; Thiophenes; Thrombomodulin; Time Factors; Tissue Plasminogen Activator	2004
Losartan increases bradykinin levels in hypertensive humans. Circulation, 2005, Jan-25, Volume: 111, Issue:3 Topics: Acrylates; Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Bradykinin; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydroxylation; Hypertension; Imidazoles; Kallidin; Losartan; Male; Middle Aged; Peptide Fragments; Radioimmunoassay; Thiophenes	2005
Effect of angiotensin II receptor blockade on autonomic nervous system function in patients with essential hypertension. American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:4 Topics: Acrylates; Adolescent; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Antihypertensive Agents; Cross-Over Studies; Female; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Norepinephrine; Renin-Angiotensin System; Sympathetic Nervous System; Thiophenes	2006
Effect of eprosartan on the sympathetic response to cold pressor test in healthy volunteers. Autonomic neuroscience : basic & clinical, 2006, Jun-30, Volume: 126-127 Topics: Acrylates; Administration, Oral; Adolescent; Adult; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cold Temperature; Double-Blind Method; Female; Heart Rate; Humans; Imidazoles; Losartan; Male; Middle Aged; Sympathetic Nervous System; Thiophenes; Time Factors	2006
[Role of the renin-angiotensin system on the sympathetic response induced by the cold pressor test in humans]. Investigacion clinica, 2007, Volume: 48, Issue:2 Topics: Acrylates; Adult; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cold Temperature; Double-Blind Method; Female; Humans; Imidazoles; Losartan; Male; Receptors, Angiotensin; Renin-Angiotensin System; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan	2007
Ambulatory monitoring of systolic hypertension in the elderly: Eprosartan/hydrochlorothiazide compared with losartan/hydrochlorothiazide (INSIST trial). Advances in therapy, 2010, Volume: 27, Issue:6 Topics: Acrylates; Aged; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Diuretics; Double-Blind Method; Drug Monitoring; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Imidazoles; Losartan; Male; Office Visits; Severity of Illness Index; Statistics, Nonparametric; Systole; Thiophenes; Treatment Outcome	2010
Losartan and Eprosartan Induce a Similar Effect on the Acute Rise in Serum Uric Acid Concentration after an Oral Fructose Load in Patients with Metabolic Syndrome. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2021, Volume: 2021 Topics: Acrylates; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Fructose; Humans; Hypertension; Imidazoles; Losartan; Metabolic Syndrome; Middle Aged; Thiophenes; Uric Acid	2021

Other Studies

31 other study(ies) available for losartan and eprosartan

Article	Year
Pharmacophore, drug metabolism, and pharmacokinetics models on non-peptide AT1, AT2, and AT1/AT2 angiotensin II receptor antagonists. Journal of medicinal chemistry, 2005, Jun-30, Volume: 48, Issue:13 Topics: Angiotensin II Type 1 Receptor Blockers; Benzimidazoles; Binding Sites; Biphenyl Compounds; Kinetics; Losartan; Models, Molecular; Molecular Conformation; Oxidation-Reduction; Pharmaceutical Preparations; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Structure-Activity Relationship; Tetrazoles	2005
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
CYP2C9-mediated metabolic activation of losartan detected by a highly sensitive cell-based screening assay. Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:5 Topics: Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Benzbromarone; Biotransformation; Cyclooxygenase Inhibitors; Cytochrome P-450 CYP2C9; Diclofenac; HEK293 Cells; Hep G2 Cells; Hepatocytes; Humans; Losartan; NF-E2-Related Factor 2; Semicarbazides; Sensitivity and Specificity; Time Factors; Uricosuric Agents	2011
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Effect of captopril and the nonpeptide angiotensin II antagonists, SK&F 108566 and EXP3174, on renal function in dogs with a renal artery stenosis. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2 Topics: Acrylates; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Imidazoles; Inulin; Kidney; Losartan; Regional Blood Flow; Renal Artery Obstruction; Tetrazoles; Thiophenes	1992
The antihypertensive effect of the angiotensin II receptor antagonist DuP 753 may not be due solely to angiotensin II receptor antagonism. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:2 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Decerebrate State; Enalapril; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Angiotensin; Spinal Cord; Tetrazoles; Thiophenes	1992
Characterization of renal angiotensin II receptors using subtype selective antagonists. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:3 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Dithiothreitol; Guanylyl Imidodiphosphate; Imidazoles; In Vitro Techniques; Kidney; Losartan; Oligopeptides; Pyridines; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles; Thiophenes	1992
Antihypertensive activity of the non-peptide angiotensin II receptor antagonist, SK&F 108566, in rats and dogs. Naunyn-Schmiedeberg's archives of pharmacology, 1992, Volume: 345, Issue:6 Topics: Acrylates; Angiotensin I; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Dogs; Hemodynamics; Hypertension; Imidazoles; Losartan; Male; Rats; Rats, Inbred Strains; Tetrazoles; Thiophenes	1992
Imidazole based non-peptide angiotensin II receptor antagonists. Investigation of the effect of the orientation of the imidazole ring on biological activity. Arzneimittel-Forschung, 1993, Volume: 43, Issue:11 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Female; Imidazoles; In Vitro Techniques; Losartan; Rats; Rats, Sprague-Dawley; Structure-Activity Relationship; Tetrazoles; Thiophenes; Uterine Contraction	1993
Interaction of nonpeptide angiotensin II receptor antagonists with the urate transporter in rat renal brush-border membranes. The Journal of pharmacology and experimental therapeutics, 1996, Volume: 276, Issue:1 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biological Transport; Biphenyl Compounds; Carbon Radioisotopes; Hydrogen-Ion Concentration; Imidazoles; Kidney; Kinetics; Losartan; Male; Microvilli; Naphthalenes; Rats; Rats, Sprague-Dawley; Tetrazoles; Thiophenes; Uric Acid	1996
Inhibition of sympathetic outflow by the angiotensin II receptor antagonist, eprosartan, but not by losartan, valsartan or irbesartan: relationship to differences in prejunctional angiotensin II receptor blockade. Pharmacology, 1997, Volume: 55, Issue:5 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Decerebrate State; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan	1997
The evolving role of angiotensin-II receptor blockers in cardiovascular risk reduction. Case study. American journal of hypertension, 1998, Volume: 11, Issue:11 Pt 2 Topics: Acrylates; Adult; Antihypertensive Agents; Black People; Enalapril; Female; Humans; Hypertension; Imidazoles; Losartan; Receptors, Angiotensin; Thiophenes	1998
Differential inhibition of the prejunctional actions of angiotensin II in rat atria by valsartan, irbesartan, eprosartan, and losartan. The Journal of pharmacology and experimental therapeutics, 2000, Volume: 294, Issue:1 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Dose-Response Relationship, Drug; Heart; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptors, Adrenergic, alpha; Receptors, Angiotensin; Sympathetic Nervous System; Tetrazoles; Thiophenes; Valine; Valsartan	2000
In vitro inhibition screening of human hepatic P450 enzymes by five angiotensin-II receptor antagonists. European journal of clinical pharmacology, 2000, Volume: 56, Issue:2 Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Cytochrome P-450 Enzyme System; Drug Interactions; Enzyme Inhibitors; Humans; Imidazoles; In Vitro Techniques; Inhibitory Concentration 50; Irbesartan; Losartan; Microsomes, Liver; Protein Isoforms; Tetrazoles; Thiophenes; Valine; Valsartan	2000
Can angiotensin II receptor blockers be used in patients who have developed a cough or angioedema as a result of taking an ACE inhibitor? Cleveland Clinic journal of medicine, 2001, Volume: 68, Issue:3 Topics: Acrylates; Angioedema; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Black or African American; Clinical Trials as Topic; Cough; Female; Humans; Imidazoles; Irbesartan; Losartan; Male; Randomized Controlled Trials as Topic; Sex Factors; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan	2001
Differential effects of eprosartan and losartan at prejunctional angiotensin II receptors. Naunyn-Schmiedeberg's archives of pharmacology, 2001, Volume: 363, Issue:5 Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Dogs; Dose-Response Relationship, Drug; Electric Stimulation; Female; Heart Ventricles; Imidazoles; Losartan; Male; Presynaptic Terminals; Pulmonary Artery; Rats; Rats, Wistar; Receptors, Angiotensin; Thiophenes; Vasoconstrictor Agents; Ventricular Function	2001
Synthesis and study of a cyclic angiotensin II antagonist analogue reveals the role of pi--pi interactions in the C-terminal aromatic residue for agonist activity and its structure resemblance with AT(1) non-peptide antagonists. Bioorganic & medicinal chemistry, 2001, Volume: 9, Issue:6 Topics: Acrylates; Angiotensin II; Animals; Antihypertensive Agents; Biochemistry; Biphenyl Compounds; Drug Design; Imidazoles; Irbesartan; Losartan; Magnetic Resonance Spectroscopy; Male; Models, Molecular; Peptides, Cyclic; Rabbits; Structure-Activity Relationship; Tetrazoles; Thiophenes	2001
Application of capillary zone electrophoresis to the screening of some angiotensin II receptor antagonists. Electrophoresis, 2002, Volume: 23, Issue:2 Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Benzoates; Biphenyl Compounds; Chemical Fractionation; Electrophoresis, Capillary; Imidazoles; Irbesartan; Losartan; Mathematical Computing; Molecular Structure; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan	2002
Non-peptide angiotensin II receptor antagonists: chemical feature based pharmacophore identification. Journal of medicinal chemistry, 2003, Feb-27, Volume: 46, Issue:5 Topics: Acrylates; Algorithms; Angiotensin II; Biphenyl Compounds; Databases, Factual; Imidazoles; Lactones; Losartan; Models, Molecular; Molecular Conformation; Pyridines; Quantitative Structure-Activity Relationship; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Sulfones; Tetrazoles; Thiophenes	2003
Cardiology patient page. Angiotensin receptor blockers. Circulation, 2003, Jun-24, Volume: 107, Issue:24 Topics: Acrylates; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Diuretics; Dizziness; Drug Combinations; Drug Interactions; Heart Failure; Humans; Hypertension; Imidazoles; Irbesartan; Kidney Diseases; Losartan; Olmesartan Medoxomil; Telmisartan; Tetrazoles; Thiophenes; Valine; Valsartan	2003
[Dosage equivalents of AT1-receptor antagonists available in Germany]. Deutsche medizinische Wochenschrift (1946), 2003, Oct-31, Volume: 128, Issue:44 Topics: Acrylates; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Clinical Trials as Topic; Germany; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Olmesartan Medoxomil; Placebos; Telmisartan; Tetrazoles; Therapeutic Equivalency; Thiophenes; Time Factors; Valine; Valsartan	2003
Angiotensin type 1 receptor blockers induce peroxisome proliferator-activated receptor-gamma activity. Circulation, 2004, May-04, Volume: 109, Issue:17 Topics: 3T3 Cells; Acrylates; Adipocytes; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Cell Differentiation; Genes, Reporter; Imidazoles; Insulin Resistance; Irbesartan; Losartan; Luciferases; Mice; PC12 Cells; Rats; Receptors, Cytoplasmic and Nuclear; Receptors, Retinoic Acid; Recombinant Fusion Proteins; Retinoid X Receptors; Telmisartan; Tetrazoles; Thiophenes; Transcription Factors; Transfection	2004
Peripheral sympatholytic actions of four AT1 antagonists: are they relevant for long-term antihypertensive efficacy? Journal of hypertension, 2005, Volume: 23, Issue:10 Topics: Acrylates; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Electric Stimulation; Imidazoles; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Inbred SHR; Sympathetic Fibers, Postganglionic; Sympatholytics; Tetrazoles; Thiophenes; Time Factors; Treatment Outcome	2005
Interaction of angiotensin receptor type 1 blockers with ATP-binding cassette transporters. Biopharmaceutics & drug disposition, 2010, Volume: 31, Issue:2-3 Topics: Acrylates; Angiotensin II Type 1 Receptor Blockers; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP-Binding Cassette Transporters; Benzimidazoles; Biological Transport; Biphenyl Compounds; Digoxin; Fluoresceins; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Membrane Transport Proteins; Mice; Multidrug Resistance-Associated Protein 2; Olmesartan Medoxomil; Tetrazoles; Thiophenes	2010
Influence of initial angiotensin receptor blockers on treatment persistence in uncomplicated hypertension: A nation-wide population-based study. Clinical and experimental hypertension (New York, N.Y. : 1993), 2016, Volume: 38, Issue:3 Topics: Acrylates; Adult; Aged; Angiotensin Receptor Antagonists; Biphenyl Compounds; Cohort Studies; Female; Humans; Hypertension; Imidazoles; Irbesartan; Losartan; Male; Medication Adherence; Middle Aged; Outcome Assessment, Health Care; Republic of Korea; Retrospective Studies; Risk Factors; Tetrazoles; Thiophenes; Valsartan	2016
HPLC method transfer study for simultaneous determination of seven angiotensin II receptor blockers. Journal of separation science, 2020, Volume: 43, Issue:8 Topics: Acrylates; Angiotensin Receptor Antagonists; Benzimidazoles; Biphenyl Compounds; Chlorthalidone; Chromatography, High Pressure Liquid; Hydrochlorothiazide; Imidazoles; Irbesartan; Losartan; Molecular Structure; Software; Tablets; Tetrazoles; Thiophenes; Valsartan	2020
ATR1 Angiotensin II Receptor Reduces Hemoglobin S Polymerization, Phosphatidylserine Exposure, and Increases Deformability of Sickle Cell Disease Erythrocytes. Cell biochemistry and biophysics, 2022, Volume: 80, Issue:4 Topics: Acrylates; Anemia, Sickle Cell; Angiotensin II; Annexin A5; Erythrocytes; Hemoglobin, Sickle; Humans; Imidazoles; Losartan; Phosphatidylserines; Polymerization; Receptor, Angiotensin, Type 1; Thiophenes	2022