losartan has been researched along with cyclic gmp in 26 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 12 (46.15) | 18.2507 |
| 2000's | 12 (46.15) | 29.6817 |
| 2010's | 2 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chaki, S; Inagami, T | 1 |
| Abassi, ZA; Golomb, E; Keiser, HR; Kelly, G; Klein, H | 1 |
| Bottari, SP; Brechler, V; de Gasparo, M; Jones, PW; Levens, NR | 1 |
| Chevalier, RL; McDowell, KA; Norling, LL; Thornhill, BA | 1 |
| Garrido, MR; Israel, A; Saavedra, JM; Strömberg, C; Torres, M; Tsutsumi, K | 1 |
| Carey, RM; Jaffa, AA; Margolius, HS; Siragy, HM | 1 |
| Carey, RM; Siragy, HM | 2 |
| Gohlke, P; Pees, C; Unger, T | 2 |
| Carey, RM; Guerrant, RL; Jin, XH; Siragy, HM; Wang, ZQ | 1 |
| Lew, WY; Yasuda, S | 1 |
| Fornes, P; Gervais, M; Giudicelli, JF; Richer, C | 1 |
| Basso, N; González Bosc, L; Kurnjek, ML; Müller, A | 1 |
| Clanachan, AS; Dyck, JR; Ford, WR; Jugdutt, BI; Kumar, D; Lopaschuk, GD; Xu, Y | 1 |
| Jugdutt, BI; Menon, V; Xu, Y | 1 |
| Carey, RM; De Gasparo, M; El-Kersh, MA; Siragy, HM; Webb, RL | 1 |
| Abukhalaf, IK; Bayorh, MA; Eatman, D; Ganafa, AA; Silvestrov, N; Socci, RR | 1 |
| Charles, CJ; Espiner, EA; Frampton, CM; Nicholls, MG; Rademaker, MT; Richards, AM | 1 |
| Clanachan, AS; Ford, WR; Jugdutt, BI; Kumar, D; Menon, V | 1 |
| Bogdanska, J; Jovanoska, E; Korneti, P; Kostova, E; Petrov, S; Slaninka-Miceska, M | 1 |
| Hiyoshi, H; Okamoto, H; Takano, M; Yayama, K | 1 |
| Barbella, Y; Israel, A; Zavala, L | 1 |
| Carstens, J; Pedersen, EB | 1 |
| Cai, Z; Gu, M; Guo, J; Li, WJ; Wang, Z; Xu, M; Zheng, DC | 1 |
| Das, S; Pandey, KN; Periyasamy, R | 1 |
2 trial(s) available for losartan and cyclic gmp
| Article | Year |
|---|---|
Combined inhibition of angiotensin II and endothelin suppresses the brain natriuretic peptide response to developing heart failure.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Atrial Natriuretic Factor; Blood Pressure; Bosentan; Cardiac Output; Cardiac Output, Low; Cardiac Pacing, Artificial; Cyclic GMP; Endothelin Receptor Antagonists; Endothelin-1; Female; Infusions, Parenteral; Losartan; Natriuretic Peptide, Brain; Renin; Sheep; Sulfonamides | 2004 |
Renal effects of urodilatin in healthy subjects are independent of blockade of the cyclooxygenase and angiotensin II receptor.
Topics: Adult; Aldosterone; Angiotensin Receptor Antagonists; Atrial Natriuretic Factor; Blood Pressure; Cross-Over Studies; Cyclic GMP; Diuresis; Diuretics; Glomerular Filtration Rate; Heart Rate; Hematocrit; Humans; Indomethacin; Kidney; Kidney Function Tests; Lithium; Losartan; Male; Natriuresis; Peptide Fragments; Prostaglandin-Endoperoxide Synthases; Prostaglandins; Receptors, Angiotensin; Renal Plasma Flow, Effective; Renin; Single-Blind Method | 2008 |
24 other study(ies) available for losartan and cyclic gmp
| Article | Year |
|---|---|
A newly found angiotensin II receptor subtype mediates cyclic GMP formation in differentiated Neuro-2A cells.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Binding Sites; Biphenyl Compounds; Cell Differentiation; Cyclic GMP; Imidazoles; Losartan; Neuroblastoma; Pyridines; Receptors, Angiotensin; Tetrazoles; Tumor Cells, Cultured | 1992 |
Losartan improves the natriuretic response to ANF in rats with high-output heart failure.
Topics: Angiotensin Receptor Antagonists; Animals; Atrial Natriuretic Factor; Biphenyl Compounds; Cyclic GMP; Drug Interactions; Heart Failure; Imidazoles; Kidney; Losartan; Male; Natriuresis; Rats; Rats, Wistar; Renin-Angiotensin System; Sodium; Tetrazoles | 1994 |
Agonistic and antagonistic properties of angiotensin analogs at the AT2 receptor in PC12W cells.
Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Cyclic GMP; Imidazoles; Losartan; Oligopeptides; PC12 Cells; Pyridines; Rats; Receptors, Angiotensin; Tetrazoles | 1993 |
Unilateral ureteral obstruction increases glomerular soluble guanylyl cyclase activity.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Cyclic GMP; Imidazoles; Kidney Glomerulus; Losartan; Male; Nitroprusside; Phosphoric Diester Hydrolases; Rats; Rats, Sprague-Dawley; Tetrazoles; Ureteral Obstruction; Vasoconstrictor Agents | 1995 |
Angiotensin II receptor subtypes and phosphoinositide hydrolysis in rat adrenal medulla.
Topics: Adrenal Medulla; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Binding, Competitive; Biphenyl Compounds; Cyclic GMP; Hydrolysis; Imidazoles; Losartan; Male; Phosphatidylinositols; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Tetrazoles | 1995 |
Renin-angiotensin system modulates renal bradykinin production.
Topics: Angiotensin II; Animals; Biphenyl Compounds; Bradykinin; Cyclic GMP; Dinoprostone; Dogs; Drug Combinations; Extracellular Space; Female; Hemodynamics; Imidazoles; Kidney; Losartan; Microdialysis; Oligopeptides; Renal Circulation; Renin-Angiotensin System; Tetrazoles | 1996 |
The subtype 2 (AT2) angiotensin receptor mediates renal production of nitric oxide in conscious rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Cyclic GMP; Enzyme Inhibitors; Extracellular Space; Female; Imidazoles; Indazoles; Kidney; Losartan; Microdialysis; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System; Sodium; Tetrazoles | 1997 |
AT2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cerebrovascular Disorders; Cyclic GMP; Hypertension; Imidazoles; Losartan; Male; Minoxidil; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values | 1998 |
Regulation of jejunal sodium and water absorption by angiotensin subtype receptors.
Topics: Adrenergic alpha-1 Receptor Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Cyclic AMP; Cyclic GMP; Diet, Sodium-Restricted; Dinoprostone; Dose-Response Relationship, Drug; Guanethidine; Homeostasis; Imidazoles; Intestinal Absorption; Intestinal Mucosa; Jejunum; Kinetics; Losartan; Male; Mesenteric Arteries; Oligopeptides; Prazosin; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors; Water | 1998 |
Angiotensin II exacerbates lipopolysaccharide-induced contractile depression in rabbit cardiac myocytes.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Calcium; Cells, Cultured; Chelating Agents; Cyclic GMP; Enzyme Inhibitors; Female; Heart Ventricles; Imidazoles; Indoles; Lipopolysaccharides; Losartan; Male; Mitochondria; Muscle Fibers, Skeletal; Myocardial Contraction; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rabbits; Receptors, Angiotensin; Sepsis; Ventricular Function | 1999 |
Protective role of the angiotensin AT2 receptor in a renal wrap hypertension model.
Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cyclic GMP; Hypertension, Renovascular; Imidazoles; Kidney; Losartan; Nitric Oxide; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Vasodilation | 1999 |
Combined selective angiotensin II AT1-receptor blockade and angiotensin I-converting enzyme inhibition on coronary flow reserve in postischemic heart failure in rats.
Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Cardiomegaly; Coronary Circulation; Cyclic GMP; Heart Failure; Hemodynamics; Indoles; Losartan; Male; Myocardial Infarction; Myocardial Ischemia; Myocardium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System | 1999 |
Effect of chronic angiotensin II inhibition on the cardiovascular system of the normal rat.
Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Body Weight; Cardiovascular System; Collagen; Cyclic GMP; DNA; Drinking; Enalapril; Fibrosis; Losartan; Male; Myocardium; NADPH Dehydrogenase; Rats; Rats, Wistar; Reference Values; Systole; Time Factors | 2000 |
AT(1) and AT(2) receptor expression and blockade after acute ischemia-reperfusion in isolated working rat hearts.
Topics: Adenosine; Adrenergic alpha-Agonists; Anaerobiosis; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Cyclic GMP; Enalaprilat; Gene Expression Regulation; Heart; Hemodynamics; In Vitro Techniques; Losartan; Mitogen-Activated Protein Kinases; Myocardial Reperfusion; Myocardial Reperfusion Injury; p38 Mitogen-Activated Protein Kinases; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors; Ventricular Function, Left | 2002 |
Cardioprotection after angiotensin II type 1 blockade involves angiotensin II type 2 receptor expression and activation of protein kinase C-epsilon in acutely reperfused myocardial infarction in the dog. Effect of UP269-6 and losartan on AT1 and AT2-recep
Topics: Angiotensin Receptor Antagonists; Animals; Blood Volume; Calcium Channels; Cardiotonic Agents; Cyclic GMP; Dogs; Enzyme Activation; Female; Hemodynamics; Inositol 1,4,5-Trisphosphate Receptors; Isoenzymes; Losartan; Male; Myocardial Infarction; Myocardial Reperfusion; Myocardium; Protein Kinase C; Protein Kinase C-epsilon; Pyrimidines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Receptors, Cytoplasmic and Nuclear; RNA, Messenger; Tetrazoles; Time Factors; Ventricular Function, Left | 2000 |
Differences in AT2 -receptor stimulation between AT1 -receptor blockers valsartan and losartan quantified by renal interstitial fluid cGMP.
Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Cyclic GMP; Extracellular Space; Female; Imidazoles; Injections, Intravenous; Kidney; Losartan; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Tetrazoles; Valine; Valsartan | 2002 |
Effect of angiotensin AT2 receptor stimulation on vascular cyclic GMP production in normotensive Wistar Kyoto rats.
Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Cyclic GMP; Endothelium, Vascular; Enzyme Inhibitors; Imidazoles; Losartan; Male; Minoxidil; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Pyridines; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin | 2003 |
Effect of losartan on oxidative stress-induced hypertension in Sprague-Dawley rats.
Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Aorta; Biomarkers; Blood Pressure; Buthionine Sulfoximine; Cyclic AMP; Cyclic GMP; Dinoprost; Disease Models, Animal; Enzyme Inhibitors; Epoprostenol; F2-Isoprostanes; Glutathione; Heart Rate; Hypertension; Kidney; Losartan; Male; Models, Cardiovascular; Nitric Oxide; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxides; Thromboxane A2; Treatment Outcome | 2003 |
Effect of angiotensin II type 2 receptor blockade on activation of mitogen-activated protein kinases after ischemia-reperfusion in isolated working rat hearts.
Topics: Angiotensin II Type 2 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cardiac Output; Coronary Circulation; Cyclic GMP; Disease Models, Animal; Enalaprilat; Enzyme Activation; Heart; Losartan; Male; Mitogen-Activated Protein Kinases; Models, Cardiovascular; Phosphorylation; Protein Kinase C; Protein Kinase C-epsilon; Rats; Rats, Sprague-Dawley; Reperfusion Injury; RNA, Messenger | 2003 |
Effect of angiotensin II type 1 (AT1) receptor antagonist on the endothelial dysfunction in spontaneously hypertensive rats in correlation with the nitric oxide system.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Cyclic GMP; Endothelin-1; Endothelium, Vascular; Hypertension; Losartan; Nitric Oxide; Rats; Rats, Inbred SHR | 2003 |
Stimulation of cyclic GMP production via AT2 and B2 receptors in the pressure-overloaded aorta after banding.
Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Valve Stenosis; Bradykinin; Bradykinin B2 Receptor Antagonists; Cyclic GMP; Hypertension; Imidazoles; Ligation; Losartan; Male; Mice; Mice, Inbred ICR; Models, Animal; Nitric Oxide; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Renin; RNA, Messenger; Up-Regulation; Vasoconstriction | 2004 |
Neurohumoral mechanism in the natriuretic action of intracerebroventricular administration of renin.
Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Atrial Natriuretic Factor; Brain; Cyclic GMP; Diuresis; Injections, Intraventricular; Losartan; Male; Natriuresis; Neurotransmitter Agents; Peptides, Cyclic; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Atrial Natriuretic Factor; Renin; Time Factors | 2004 |
Losartan Preserves Erectile Function by Suppression of Apoptosis and Fibrosis of Corpus Cavernosum and Corporal Veno-Occlusive Dysfunction in Diabetic Rats.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Collagen; Cyclic GMP; Diabetes Mellitus, Experimental; Fibrosis; Losartan; Male; Muscle, Smooth; Nitrites; Penile Erection; Rats; Rats, Sprague-Dawley; Signal Transduction; Sildenafil Citrate; Smad Proteins; Transforming Growth Factor beta1 | 2017 |
Genetic disruption of guanylyl cyclase/natriuretic peptide receptor-A upregulates renal (pro) renin receptor expression in Npr1 null mutant mice.
Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cyclic GMP; Female; Kidney; Losartan; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Prorenin Receptor; Receptor, Angiotensin, Type 1; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface | 2019 |