losartan and captopril

losartan has been researched along with captopril in 401 studies

Research

Studies (401)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	144 (35.91)	18.2507
2000's	163 (40.65)	29.6817
2010's	79 (19.70)	24.3611
2020's	15 (3.74)	2.80

Authors

Authors	Studies
Abbenante, G; Fairlie, DP; Leung, D	1
Funakoshi, J; Kakumoto, M; Okumura, K; Sakaeda, T; Takara, K; Tanigawara, Y	1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL	1
Balsamo, A; Breschi, MC; Calderone, V; Digiacomo, M; Macchia, M; Martelli, A; Martinotti, E; Minutolo, F; Rapposelli, S; Rossello, A; Testai, L	1
Abrego, V; Angeles, E; Balboa, MA; Camacho, B; Díaz-Barriga, S; López-Castañares, R; Martínez, L; Romero, A; Torres, LA; Velázquez, AM	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ	1
Abrego, VH; Amaro-Recillas, HA; Angeles, E; Marroquín-Pascual, JL; Martínez, L; Martínez-Pérez, B; Moya-Hernández, R; Rodríguez-Barrientos, D; Rojas-Hernández, A; Rueda-Jackson, JC; Torres, LA	1
Ekins, S; Williams, AJ; Xu, JJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M	1
Fregly, MJ; Rowland, NE	2
Li, T; Zimmerman, BG	1
Campan, M; Costerousse, O; Desgranges, C; Gadeau, AP; Millet, D	1
Andries, M; Denef, C; Robberecht, W	1
Garcia, R; Qing, G	1
Brooks, DP; DePalma, PD; Ruffolo, RR	1
Brooks, DP; Edwards, RM; Gellai, M; Jugus, J; Ohlstein, EH; Ruffolo, RR; Sulpizio, A; Vickery, L; Weinstock, J	1
Blantz, RC; De Nicola, L; Gabbai, FB; Keiser, JA	1
Charles, CJ; Espiner, EA; Fitzpatrick, MA; Ikram, H; Rademaker, MT; Yandle, TG	1
Carretero, O; Fenoy, FJ; Roman, RJ; Scicli, G	1
Jackson, EK	1
Cachofeiro, V; Nasjletti, A; Sakakibara, T	1
Duncia, JV; Hart, SD; Timmermans, PB; Wong, PC	1
Hajj-ali, AF; Zimmerman, BG	1
Cogan, MG; Liu, FY; Timmermans, PB; Wong, PC; Xie, MH	2
Daugherty, S; Fonken, SJ; Goldman, S; Lee, RW; Morkin, E; Raya, TE; Timmermans, PB; Wong, PC	1
Bennett, T; Compton, AM; Foulkes, R; Gardiner, SM; Hughes, B; Kemp, PA	1
Batin, P; Bennett, T; Compton, AM; Gardiner, SM	1
Hart, SD; Timmermans, PB; Wong, PC	1
Carini, DJ; Chiu, AT; Duncia, JV; Johnson, AL; Price, WA; Timmermans, PB; Wexler, RR; Wong, PC	1
Anversa, P; Capasso, JM; Herman, MV; Li, P; Meggs, LG	1
Abassi, ZA; Cuda, G; Golomb, E; Keiser, HR; Panchal, VR; Stylianou, M; Trachewsky, D	1
Morita, T; Nishimura, N; Takase, H	1
Lupichuk, SM; Tabrizchi, R	1
Araki, M; Imai, S; Kanda, T; Kobayashi, I; Murata, K; Suzuki, T	1
Leomil Neto, M; Michelini, LC; Pontieri, V; Santos, CM	1
Gibson, KJ; Lumbers, ER; Stevenson, KM	1
Araki, M; Imai, S; Kanda, T; Kobayashi, I; Murata, K; Nakano, M; Suzuki, T	1
Abe, K; Fu, LP; Kanazawa, M; Kohzuki, M; Obara, K; Saito, T; Yasujima, M; Yoshida, K	1
Atucha, NM; García-Estañ, J; Quesada, T; Vargas, F	1
Gomi, T; Goto, A; Hirawa, N; Ikeda, T; Kawabata, Y; Nagata, T; Ohshima, N; Ono, H; Uehara, Y; Yagi, S	1
Hodgson, WC; Hopkins, BJ; Sutherland, SK	1
Jackson, EK; Kost, CK; Li, P; Pfeifer, CA	1
Guo, X; Guo, ZG; Ling, Q; Su, Z	1
Mao, L; Rockman, HA; Ross, J; Wachhorst, SP	1
Gardner, PL; Knabb, MT; Mbuy, GN	1
Eerdmans, PH; Janssen, BJ; Smits, JF	1
Chen, K; Zimmerman, BG	1
Johnson, AK; Thunhorst, RL	1
Hamakubo, T; Inagami, T; Yoshida, M	1
Feng, CJ; Kadowitz, PJ; Nossaman, BD; Wang, J	1
Majewski, H; Rechtman, M	1
Boudier, HA; Daemen, MJ; Nelissen-Vrancken, HJ; Smits, JF	1
Abe, J; Kurokawa, K; Ochiai, M; Ohno, M; Okazaki, H; Taguchi, J; Takuwa, Y	1
Ida, F; Krieger, EM; Moreira, ED; Pires, MD	1
da Silva, SV; da Silva, VJ; Salgado, HC; Salgado, MC	1
Abassi, ZA; Golomb, E; Keiser, HR; Klein, H	1
Nelson, LD; Osborn, JL	1
Mimran, A; Nafrialdi, N; Ribstein, J; Valentin, JP	1
Fukamizu, A; Hatae, T; Kajiwara, N; Murakami, K; Seo, MS; Sugimura, K; Sugiyama, F; Takahashi, S; Takimoto, E; Yagami, K	1
Aronoff, GR; Brier, ME; Bunke, CM; Lathon, PV	1
Bergelson, BA; Gavras, H; Gavras, I; Ruocco, NA; Yu, TK	1
Goldman, S; Johnson, CS; Milavetz, JJ; Morkin, E; Raya, TE	1
Duan, J; Fernandes, BH; Jaramillo, J; Jung, GL; Mathis, D; McLeod, AL	1
Deck, CC; Gaballa, MA; Raya, TE	1
Haneda, T; Kikuchi, K; Miyata, S; Osaki, J	1
Kageyama, Y; Matsumoto, A; Murakami, M; Naitoh, M; Saruta, T; Suzuki, H; Tsujimoto, G	1
Dunham, EW; Zhang, X; Zimmerman, BG	1
Heininger, F; Phillips, MI; Toffolo, S	1
Bennett, T; Gardiner, SM; Kemp, PA; March, JE	1
Head, RJ; Irvine, RJ; White, JM	1
Born, GV; Brown, MJ; Cardona-Sanclemente, LE; Medina, R	1
Abe, K; Kanazawa, M; Kohzuki, M; Liu, PF; Obara, K; Saito, T; Sato, T; Yasujima, M; Yoshida, K	1
Chang, PI; Cowley, AJ; Deedwania, PC; Martinez, FA; Meurers, G; Ney, DE; Pitt, B; Segal, R; Snavely, DB; Thomas, I	1
Amiri, F; Garcia, R; Haddad, G	1
Haigh, RM; Redemann, N; van Meel, JC	1
Angulo, J; Llergo, JL; Peiró, C; Regadera, J; Rodríguez-Mañas, L; Sánchez-Ferrer, A; Sánchez-Ferrer, CF	1
Morrell, NW	1
Jensen, BV; Nielsen, SL	1
Achard, JM; Fernandez, LA; Fournier, A	1
Bartoli, E; Catena, C; Sechi, LA	1
Ball, SG	1
Cachofeiro, V; Lahera, V; Maeso, R; Muñoz-García, R; Navarro-Cid, J; Rodrigo, E; Ruilope, LM	1
Angulo, J; Llergo, JL; López-Novoa, JM; Peiró, C; Rodríguez-López, A; Rodríguez-Mañas, L; Sánchez-Ferrer, CF	1
Cheng, EY; Decker, RS; Firlit, CF; Kaplan, WE; Lang, S; Lee, C; Palmer, LS	1
Abdi, A; Johns, EJ	1
Haneda, T; Kikuchi, K; Takeda, H	1
Das, N; Gulati, K; Khattar, S; Lall, SB; Peshin, SS; Seth, SD	1
Naitoh, T; Shikada, K; Tanaka, S; Yotsumoto, T	1
Carvalho, CR; Gontijo, JA; Saad, MJ; Thirone, AC; Velloso, LA	1
Heller, J; Horácek, V; Kramer, HJ	1
Pitt, B	2
Cannizzaro, S; Di Pasquale, P; Iachininoto, R; Longo, AM; Maringhini, G; Paterna, S	1
Hatta, T; Itoh, H; Kawa, T; Kiyama, M; Miki, S; Moriguchi, J; Morimoto, S; Nakagawa, M; Nakamura, K; Nakata, T; Sasaki, S; Takeda, K; Uchida, A	1
Oberhauser, V; Rump, LC; Schollmeyer, P; Schwertfeger, E	1
Mineshita, S; Shimakura, K; Wang, LM; Xu, ZH; Yamamoto, T	1
Chan, R; Irvine, RJ; White, J	1
Mangiapane, ML; Peters, BR	1
Amann, K; Bohlender, J; Drab, M; Ganten, D; Wagner, J; Wienen, W	1
Cifkova, R; Harron, DW; Karpov, YA; Lepe, L; Oigman, W; Roca-Cusachs, A	1
Busatto, VC; de Moraes, AC; Gomes, Mda G; Milanez, Mda C; Mill, JG	1
Jackson, EK; Kost, CK; Li, P; Williams, DS	1
Bucca, V; Di Pasquale, P; Paterna, S; Scalzo, S	1
Leary, A; Lim, P; MacDonald, T; Naas, A; Shiels, P	1
Buczko, W; Chabielska, E; Golatowski, J; Pawlak, R	1
Borland, JA; Catravas, JD; Chester, AH; Crabbe, S; Parkerson, JB; Yacoub, MH	1
Inada, M; Masaki, H; Matsubara, H; Mori, Y	1
Boucher, D; Grose, JH; Kingma, I; Larivière, R; Lebel, M	1
Scholze, J; Stapff, M	1
Beltz, TG; Colombari, DS; Johnson, AK; Menani, JV; Thunhorst, RL	1
Kawada, T; Miyano, H; Sato, T; Shishido, T; Sugimachi, M; Sunagawa, K; Yoshimura, R	1
Barrett, JD; Eggena, P; Hori, MT; Kamide, K; Tuck, ML; Zhu, JH	1
Struthers, AD	1
Blair-West, JR; Carey, KD; Denton, DA; Shade, RE; Weisinger, RS	1
Brown, NJ; Gainer, JV; King, DJ; Loveland, A; Morrow, JD	1
Fuster, D; Lomeña, F; Oppenheimer, F; Paz Marco, M; Setoain, FJ	1
Baumohl, Y; Blatt, A; Cotter, G; Golik, A; Kaluski, E; Litinsky, I; Metzkor-Cotter, E; Moshkovitz, Y; Vered, Z; Zaidenstein, R	1
Lang, SM; Schiffl, H	1
Barnes, M; Buckley, JM; Carabello, BA; Conrad, CC; Cooper, G; DeFreyte, G; Dell'Italia, LJ; Koide, M; Tomanek, RJ; Wei, CC; Zile, MR	1
Chen, TH; Guo, ZG; Ling, Q	1
Dickstein, K; Kjekshus, J	3
Azizi, M	1
Anwar, M; Ibrahim, IN; Kadowitz, PJ; Kaye, AD; Nossaman, BD; Smith, DE	1
Cheng, HF; Harris, RC; Ichikawa, I; McKanna, JA; Miyazaki, Y; Wang, JL; Zhang, MZ	1
Bornstein, SR; Correa, FM; Ehrhart-Bornstein, M; Hilbers, U; Jöhren, O; Peters, J; Saavedra, JM	1
Chen, HZ; Peng, TQ; Pu, SY; Shen, XD; Yang, YZ; Zhang, GX	1
Baan, J	1
Bucca, V; Cannizzaro, S; Di Pasquale, P; Giubilato, A; Paterna, S; Scalzo, S	1
Rauch, M; Schmid, HA	1
Camm, AJ; Dickstein, K; Klinger, GH; Konstam, MA; Martinez, FA; Neaton, J; Pitt, B; Poole-Wilson, P; Riegger, G; Segal, R; Sharma, D; Thiyagarajan, B	1
Brooksby, P; Cowley, AJ; Klinger, G; Pitt, B; Robinson, PJ; Segal, R	1
Bech, JN; Müller, GA; Pedersen, EB; Schulz, E	1
Ahiskali, R; Akalin, S; Budak, Y; Ekicioglu, G; Emerk, K; Ersöz, O; Kuçükkaya, B; Yavuz, DG	1
Gould, RJ; Grossman, W; Kusma, SE; Lynch, JJ; Painter, CA; Stump, GL; Thomas, JM; Wallace, AA	1
Buhagiar, KA; Gray, DF; Hansen, PS; Mihailidou, AS; Rasmussen, HH	1
Kim, HS; Oh, BH; Youn, TJ	1
Cheung, PK; Saward, L; Wilson, DP; Zahradka, P	1
Riegger, GA	1
Brennan, G; Dargie, HJ; O'Kane, KP; Reid, JL; Robb, S; Squire, IB	1
Topol, E	1
Asada, Y; Hirose, K; Iino, M; Takasaka, T; Yamazawa, T	1
Freudenthaler, SM; Gleiter, CH; Körner, T; Schreeb, K	1
Arendshorst, WJ; Coffman, TM; Oliverio, MI; Ruan, X	1
Anderson, P; Bolger, G; Jaramillo, J; Jung, G; Lamarre, D; Liard, F; Pilote, L; Simoneau, B; Thibeault, D; Vigeant, JC	1
Janssen, BJ; Oosting, J; Struijker-Boudier, HA	1
Kamata, K; Mizutani, K	1
Dolnikoff, MS; Furukawa, LN; Heimann, JC; Machado, UF; Okamoto, MM; Prada, P	1
Camera, M; Di Santo, A; Lorenzet, R; Napoleone, E; Tremoli, E	1
Vidt, DG	1
Berger, D	1
Browne, AE; Chatterjee, K; Chou, TM; Lee, RJ; Parmley, WW; Pulukurthy, S; Sievers, RE; Sudhir, K; Sun, Y; Zhu, B	1
Beresewicz, A; Maczewski, M	1
Fukumori, R; Hosokawa, H; Kambe, T; Kubo, T	1
Fischerova, B; Pluhacek, L; Spinar, J; Spinarova, L; Toman, J; Vitovec, J	2
Banerjee, T; Clark, AL; Cleland, JG; Thackray, S; Witte, K	1
Fitch, GK; Weiss, ML	1
Califf, RM; Velazquez, EJ	1
Camm, AJ; Dickstein, K; Klinger, GH; Konstam, MA; Martinez, FA; Neaton, J; Pitt, B; Poole-Wilson, PA; Riegger, G; Segal, R; Sharma, D; Thiyagarajan, B	1
Albertin, G; Malendowicz, LK; Markowska, A; Mazzocchi, G; Nussdorfer, GG	1
Bittner, V; Ford, T; Goldman, S; Gradman, A; Kinan, D; Konstam, MA; La Bresh, K; Lewis, W; Patten, RD; Ramahi, T; Rand, W; Segal, R; Self, KS; Smith, JJ; Thomas, I; Udelson, JE	1
Einecke, D	1
Cowley, AJ; Harrison, M; Houghton, AR	1
Jackson, EA; Trojian, TH	1
Cohen-Solal, A	1
Barr, E; Conlin, PR; DeLucca, P; Demopoulos, L; Fletcher, C; Gazdick, L; Moore, TJ; Swartz, SL	1
Kromer, EP	1
Hall, A	1
Meyer, FP	1
Gansevoort, RT; van Veldhuisen, DJ	1
Lye, M	1
Mahé, I	1
Dhalla, NS; Hayashi, H; Nasa, Y; Takeo, S; Tanonaka, K; Yabe, K; Yamaguchi, F	1
Cowley, AJ; Dasbach, EJ; Pitt, B; Rich, MW; Santanello, NC; Segal, R; Wiens, BL	1
Chiba, S; Fukumori, R; Ibusuki, T; Kambe, T; Kubo, T	1
Orrù, P; Porcu, M	1
Chernichovski, T; Frolkis, I; Gurevitch, J; Iaina, A; Kramer, A; Matsa, M; Mohr, R; Paz, Y; Pevni, D; Shapira, I; Wollman, Y; Yuhas, Y	1
Bravo, R; Fernández-Alfonso, MS; González, C; Ruiz-Gayo, M; Somoza, B	1
Berry, C; McMurray, JJ; Norrie, J	1
Kulkarni, SK; Raghavendra, V	1
Balt, JC; Mathy, MJ; Pfaffendorf, M; van Zwieten, PA	1
Ma, CT; Yu, TZ	1
Borhani, M; Curci, JA; Kelley, BJ; Liao, S; Miralles, M; Thompson, RW	1
Deev, AD; Gorbunov, VM; Metelitsa, VI; Savina, LV	1
Chopra, K; Kulkarni, SK; Raghavendra, V	1
Bravo, R; Fernández-Alfonso, MS; González, C; Ruilope, LM; Ruiz-Gayo, M; Somoza, B	1
Miller, AB; Srivastava, P	1
Ball, KJ; Stumpe, KO; Williams, PA	1
Browne, AE; Chatterjee, K; Chou, TM; Deedwania, PC; Glantz, SA; Parmley, WW; Pulukurthy, S; Sudhir, K; Sun, YP; Zhu, BQ	1
Amaral, SL; Greene, AS; Papanek, PE	1
Badzyńska, B; Dobrowolski, L; Grzelec-Mojzesowicz, M; Sadowski, J	1
Fabiani, ME; Frauman, AG; Johnston, CI; Sourial, M; Thomas, WG	1
Andrejak, M; Fournier, A; Mazouz, H; Monge, M; Oprisiu, R	1
Aubert, JF; Brunner, H; Morgan, T	1
Auer, JW; Berent, R; Eber, B	1
Gruszka, A; Melen-Mucha, G; Mucha, S; Pawlikowski, M	1
Ogihara, T; Rakugi, H	1
Butler, DG; Zhang, DH	1
Chen, H; Pan, W; Pu, S; Shen, X; Yang, Y; Zhang, G	1
Komajda, M	1
Blantz, RC; Gabbai, FB; Khang, S; Komine, N; Wead, LM	1
Cha, DR; Ihm, CG; Kim, HJ; Lee, TW; Park, JK	1
Delbridge, L; Griffiths, C; Morgan, T	2
Israel, A; Sosa-Canache, B	1
Acet, A; Birincioglu, M; Ozer, MK; Sahna, E	1
Studney, D	1
Felder, RB; Francis, J; Weiss, RM; Zhang, ZH	1
Bkaily, G; Brochu, I; D'Orléans-Juste, P; Labonté, J	1
Burleigh, DE; Djahanbakhch, O; Mahmood, T; O'Mahony, OA; Puddefoot, JR; Vinson, GP	1
Eguchi, K; Kario, K; Shimada, K	1
Sato, H	1
Buczko, W; Kucharewicz, I; Matys, T; Pawlak, D; Pawlak, R	1
Suzuki, H	1
Gayet, JL	1
Achard, JM; Andrejak, M; Fournier, A; Godefroy, O; Slama, M	1
Martínez-Sellés, M	1
Chowdhary, S; Townend, JN	1
Filippi-Codaccioni, E; Hamon, M	1
Mareev, VIu	1
Hasegawa, T; Ideura, T; Inui, K; Minamoto, T; Morita, H; Nakamoto, Y; Nakao, N; Oda, Y; Tayama, H; Yoshimura, A	1
Danchin, N	1
Doggrell, SA	1
Kong, J; Li, YC	1
Browne, AE; Chatterjee, K; Grossman, W; Karliner, JS; Lee, RJ; Parmley, WW; Sievers, RE; Zhu, BQ	1
Falkay, G; Gaspar, R; Resch, BE; Sonkodi, S	1
Filippatos, G; Laukka, J; Soledad-Conrad, V; Uhal, BD; Wang, R; Zhuang, J	1
Dickstein, K	1
Baggi, JM; Brandi, JM; Cordeiro, JA; de Godoy, MF; Joaquim, MR; Maia, LN; Nicolau, JC; Santos, M; Vítola, JV	1
Buikema, H; de Zeeuw, D; Gschwend, S; Henning, RH; Pinto, YM; van Gilst, WH	1
Akalin, S; Akoğlu, E; Ersöz, O; Haklar, G; Küçükkaya, B; Yavuz, D	1
Lapointe, N; Pourdjabbar, A; Rouleau, JL	1
Baran, DA; Galin, I	1
Krantz, MJ	1
Chan, LY; Chuang, TD; Guh, JY; Lai, KN; Lam, MF; Leung, JC; Tang, SC; Tsang, AW	1
Blezer, EL; Braam, B; Goldschmeding, R; Hahnel, B; Joles, JA; Koomans, HA; Kriz, W; Racasan, S; van der Giezen, DM	1
Aronow, WS; Frishman, WH	1
Pfeffer, M	1
Andersen, GS; Dahlström, U; Egstrup, K; Gøtzsche, O; Lahiri, A; Møller, JE; Skagen, K	1
Jeppsson, B; Menger, MD; Riaz, AA; Sato, T; Schramm, R; Thorlacius, H; Wang, Y	1
Hagiwara, Y; Kubo, T	1
Mauger, D; Wong, W	1
Amfilochiadis, AA; Boomsma, F; Kogan, N; Osmond, DH; Papageorgiou, PC	1
Chester, AH; Hafizi, S; Yacoub, MH	1
Arteel, GE; Bradford, BU; Froh, M; Gäbele, E; Ikai, I; Isayama, F; Uesugi, T; Yamaoka, Y	1
Arneja, AS; Dhalla, NS; Ganguly, PK; Netticadan, T; Shah, KR	1
Dickstein, K; Lehto, M; Nieminen, MS; Snapinn, S; Swedberg, K	1
Borges, DR; Carvalho, LT; Gioli-Pereira, L; Kouyoumdjian, M; Nascimento, EA; Pesquero, JB; Santos, EL	1
Aukrust, P; Damås, JK; Dickstein, K; Frøland, SS; Gullestad, L; Kjekshus, J; Otterdal, K; Ueland, T; Yndestad, A	1
Higashiura, K; Shimamoto, K; Yoshida, D	1
Barros, LF; Becker, C; Carvalho, MH; de Gusmão, FM	1
Jiang, RY; Lai, WY; Ren, H; Shao, YH; Shen, QB; Xu, DL	1
Erhardt, LR	1
Shlipak, M	1
Altun, B; Caner, B; Cil, B; Ergün, EL; Günay, EC; Hekimoğlu, B; Oztürk, MH; Salanci, BV; Uğur, O	1
Bradstreet, DC; Camm, AJ; Carides, GW; Dasbach, EJ; Dickstein, K; Ikeda, LS; Konstam, MA; Martinez, FA; Neaton, JD; Pitt, B; Poole-Wilson, PA; Riegger, G; Santoro, EP; Segal, R; Sharma, D	1
Adam, M	1
Liu, GF; Liu, K; Snavely, DB; Wang, J	1
Greene, AS; Munzenmaier, DH	1
Gottsäter, A; Ohlin, AK; Ohlin, H; Tingberg, E	1
Aukrust, P; Dickstein, K; Frøland, SS; Gullestad, L; Kjekshus, J; Omland, T; Squire, IB; Ueland, T	1
Butler, DG	1
Hashimoto, A; Mori, T	1
De Godoy, MA; Rattan, S	1
Anker, SD; Banasiak, W; Cicoira, M; Clark, AL; Coats, AJ; Davos, CH; Haass, M; Pitt, B; Ponikowski, P; Poole-Wilson, PA; Senges, J; Winkler, R; Zardini, P; Zugck, C	1
Agharazii, M; Larivière, R; Lebel, M; Rodrigue, ME	1
McGuire, JJ; Smeda, JS	1
Ahn, SC; Baik, SK; Cho, MY; Choi, YH; Kim, CH; Kim, JW; Kim, MY; Kwon, SO; Park, DH; Rhim, DW	1
Akyuz, F; Temel, HE	1
Apostolakis, S; Baritaki, S; Kochiadakis, GE; Krambovitis, E; Spandidos, DA; Vlata, Z	1
Bacal, F; Bocchi, EA; Chizzola, PR; Guimarães, GV; Issa, VS; Mangini, S; Moreira, SF; Pires, PV; Silva, CP; Souza, GE	1
Bahk, TJ; Daniels, MD; Engman, DM; Leon, JS; Wang, K	1
Liu, LY; Liu, YH; Song, T; Wu, SJ; You, Y	1
Bos, AP; Florquin, S; Haitsma, JJ; Lachmann, B; Lutter, R; Merkus, MP; van der Loos, CM; van Woensel, JB; Wösten-van Asperen, RM	1
Gao, L; Kern, TS; Xi, X; Zhang, JZ	1
Antelava, NA; Gogolauri, MI; Gongadze, NV; Kezeli, TD; Pachkoriia, KZ	1
Li, XC; Zhuo, JL	1
Narkiewicz, K	1
Anand, I; Dickstein, K; Manhenke, C; Ng, L; Orn, S; Squire, IB	1
Fluharty, S; Liu, XT; Rosenfeld, CR; Vidyasagar, D; Willis, BC; Zagariya, AM	1
Cao, K; Goltzman, D; Lu, F; Miao, D; Xu, D; Zhou, C	1
Kageyama, S	1
Araujo, IG; Fonseca, FV; Lepletier, A; Mecawi, AS; Reis, LC	1
Arnoni, CP; Boim, MA; Casarini, DE; Cristovam, PC; de Andrade, MC; Pereira, LG; Schor, N	1
Badzynska, B; Sadowski, J	1
Bradstreet, DC; Goldberg, AI; Halasz, S; Lim, NY; Madonna, O; Makris, L; Mallion, JM; Sweet, CS	1
Celiński, K; Czechowska, G; Korobowicz, E; Korolczuk, A; Madro, A; Prozorow-Król, B; Słomka, M	1
Blantz, RC; Deng, A; Satriano, J; Singh, P; Tang, T; Thomson, SC; Wang, C	1
De la Iglesia Iñigo, S; Gómez-Casares, MT; Lemes Castellano, A; López Brito, J; López-Jorge, CE; Martín Cabrera, P; Molero Labarta, T; Suárez Cabrera, A	1
Bocchi, EA; Carvalho, VO; Guimarães, GV	1
Anker, SD; Belonje, AM; Dickstein, K; Ponikowski, P; van Veldhuisen, DJ; von Haehling, S; Voors, AA; Westenbrink, BD	1
Blankesteijn, WM; Daemen, MJ; Fujimoto, A; Fujimoto, S; Hofstra, L; Isobe, S; Li, P; Lovhaug, D; Narula, J; Narula, N; Petrov, A; Pitt, B; Reutelingsperger, C; Smits, JF; van den Borne, SW; Vannan, MA; Wong, ND; Zandbergen, HR; Zannad, F	1
Ararat, E; Brozovich, FV	1
Kasai, T; Shimizu, F; Takamata, A	1
Chang, HW; Chen, YM; Chiang, CK; Chueh, SC; Ho, YL; Hsieh, BS; Huang, JW; Huang, KH; Lin, WC; Lin, YH; Liu, KL; Wang, SM; Wu, KD; Wu, VC; Yang, SY	1
Hua, YM; Liu, B; Liu, HM; Shi, K; Wang, XM; Wei, L; Zhao, SS; Zhou, TF	1
Choi, WS; Myung, CS; Nan, MH; Shin, CY; Yi, I	1
Beetz, N; Boettger, T; Braun, T; Hein, L; Kostin, S; Krüger, M; Schneider, J	1
Brody, R; Grossman, E; Peleg, E; Sharabi, Y	1
Arsenault, M; Beaudoin, J; Champetier, S; Couet, J; Lachance, D; Plante, E; Roussel, E	1
Krum, H	1
Fish, BL; Ghosh, SN; Jacobs, ER; Li, XA; Medhora, M; Moulder, JE; Semenenko, VA; Zhang, R	1
De Luca, LA; Menani, JV; Pereira, DT	1
Bos, AP; Florquin, S; Lachmann, B; Lutter, R; Specht, PA; van der Loos, CM; van Woensel, JB; Wösten-van Asperen, RM	1
Cameron, A; Ewen, M; Laing, RO; van Mourik, MS	1
Alosh, M; Huque, MF	1
Daneshtalab, N; Smeda, JS	2
Adler, F; Herndon, B; Lankachandra, K; McIff, TE; Molteni, A; Poisner, AM	1
Durand, MJ; Greene, AS; Lombard, JH; Moreno, C	1
Felehgari, V; Khazaie, H; Malek-Khosravi, S; Mozafari, H; Rahimi, M; Rahimi, Z; Rezaei, M; Vaisi-Raygani, A; Yari, K	1
Tang, CS; Wang, HX; Wang, W; Zeng, XJ; Zhang, LK; Zhang, QF	1
Chou, PC; Hsiao, PJ; Hsieh, TJ; Hung, WW; Lin, KD; Lin, T; Shin, SJ	1
Cohen, EP; Fish, BL; Moulder, JE	1
Hosseini, F; Mahmoudian, M; Nemati, F; Rahbar-Roshandel, N; Shafiei, M	1
Al-Ismaeel, H; Al-Rikabi, AC; Al-Shabanah, OA; Mansour, MA	1
Callera, JC; Da Silva, CZ; Menani, JV	2
Bardaji, B; Barreiro, L; Clemente-Lorenzo, M; Grande, MT; López-Novoa, JM; Meseguer, A; Pascual, G; Riolobos, AS; Tornavaca, O	1
Acet, A; Ozer, MK; Parlakpinar, H	1
Jan, MY; Wang, SH; Wang, WK; Wang, YY	1
Akhtar, S; Benter, IF; Dhaunsi, GS; Makki, BM; Qabazard, BA; Yousif, MH	1
Brooks, L; Dellsperger, D; Grobe, JL; Hilzendeger, AM; Liu, X; Mark, AL; Morgan, DA; Rahmouni, K; Sigmund, CD	1
Kunert-Radek, J; Lawnicka, H; Mucha, S; Pawlikowski, M; Ptasinska-Wnuk, D; Stepien, H	1
Arakawa, H; Kawabe, K; Sapru, HN	1
Asnar, DS; Colombari, DS; De Luca, LA; de Paula, PM; Menani, JV; Roncari, CF	1
Arnold, AC; Biaggioni, I; Gamboa, A; Okamoto, LE; Raj, SR; Robertson, D; Shibao, C	1
Bild, W; Ciobica, A; Hritcu, L; Stefanescu, C	1
Czuczwar, SJ; Jakubus, T; Janowska, A; Lukawski, K; Raszewski, G	1
Huang, J; Ikeda, Y; Inagami, T; Le, VP; Lin, Y; Papke, CL; Patel, M; Wagenseil, JE; Yamashiro, Y; Yanagisawa, H	1
Chiou, TT; Hsu, CY; Huang, PC; Lee, CT; Lee, YT; Ng, HY; Tain, YL	1
Akhtar, S; Al-Rashdan, I; Babiker, F; Benter, IF; Yousif, M	1
Arnaudin, I; Ben Henda, Y; Bordenave-Juchereau, S; Bridiau, N; Delatouche, R; Labidi, A; Maugard, T; Piot, JM; Sannier, F; Thiéry, V	1
Kawabe, K; Kawabe, T; Sapru, HN	1
Hashimoto, T; Kitazato, KT; Kudo, M; Liang, EI; Makino, H; Murakami, S; Nagahiro, S; Shimada, K; Tada, Y; Wada, K	1
Chen, K; Hu, B; Qiao, H; Song, L; Sun, B; Sun, HL; Wang, Q; Yan, JB; Yan, JQ; Yan, W; Zhang, Y; Zhao, SR; Zhao, XL	1
Le, VP; Wagenseil, JE; Yamashiro, Y; Yanagisawa, H	1
Hashemzadeh, M; Ju, H; Movahed, MR; Park, S	1
Anhê, GF; Antunes, E; Calmasini, F; Faria, Jde A; Mónica, FZ; Moscoso, JA; Ramos-Filho, AC	1
Hosseini, A; Jaberipour, M; Namazi, S; Razmkhah, M; Rostami-Yalmeh, J; Sahebi, E	1
Fiedler, R; Girndt, M; Seibert, E; Trojanowicz, B; Ulrich, C	1
Balakrishnan, P; Chen, YM; Chueh, SC; Hsein, YC; Kuo, CC; Wang, MJ; Wu, KD; Wu, VC	1
Dhein, S; Hoyer, A; Kempfert, J; Mohr, FW; Pritzwald-Stegmann, P	1
Bai, X; Chai, R; Guo, W; Han, Y; Li, J; Wang, H; Xu, L; Yan, W	1
Feng, Y; Li, W; Speth, RC; Sullivan, MN; Worker, CJ; Xiong, Z; Zhang, S	1
Chang, CH; Lai, MS; Lee, YC; Lin, JW; Lin, MS; Ruan, SY; Wu, LC	1
Flavahan, NA; Flavahan, S; Leung, SW; Vanhoutte, PM; Xu, A; Zhao, Y	1
Araújo, WF; Naves, MA; Ravanini, JN; Schor, N; Teixeira, VP	1
Becerril, C; Checa, M; Díaz-Piña, G; García de Alba, C; Montes, E; Ordoñez-Razo, R; Páramo, I; Ruiz, V; Vega, A	1
Chatsudthipong, V; Kongrat, S; Muanprasat, C; Srisawat, U	1
Djuric, JM; Jankovic, SM; Jankovic, SV; Kostic, M; Stojadinovic, D; Stojadinovic, M; Stojic, I	1
Ciriello, J; Messenger, SA; Moreau, JM	1
Antunes, E; Braga, GG; Costa, FTM; Dos Santos, L; Godoy, JA; Krieger, JE; Mendes, CB; Nery Diez, ACC; Pereira, DS; Vassequi-Silva, T; Vicente, CP; Werneck, CC	1
Andreotti, S; Caminhotto, Rde O; Campaãa, AB; Lima, FB; Sertié, RA	1
Clifford, PS; Davis, MJ; Hill, MA; Hong, K; Hong, Z; Meininger, GA; Sun, Z; Yang, Y; Zhao, G	1
El-Din, MM; El-Mas, MM; Elmallah, AI; Khedr, MM; Nasser, SA; Sabra, R	1
Asadikaram, G; Ebrahimi, N; Kazemi Arababadi, M; Kiani, Z; Kohan, F; Masoumi, M; Nasiri, AA; Sepehri, Z; Sheikh Fathollahi, M	1
Alves, PH; Castro, CH; Colugnati, DB; Macedo, LM; Mendes, EP; Nunes, AD; Pedrino, GR; Santos, RA; Souza, AP	1
Beheshti, F; Bideskan, AE; Hosseinian, S; Mohebbati, R; Motejadded, F; Rad, AK; Sadeghnia, H; Shafei, MN; Shahraki, S; Soukhtanloo, M	1
Azevedo, ER; Floras, JS; Mak, S; Parker, JD	1
Arellano-Mendoza, MG; Del Valle-Mondragón, L; Guevara-Salazar, JA; Montes-Rivera, JO; Quintana-Pérez, JC; Tamay-Cach, F; Trujillo-Ferrara, JG	1
Biojone, C; Casarotto, PC; Castrén, E; Diniz, CRAF; Fred, SM; Joca, SRL	1
Aronow, B; Cancelas, JA; Chang, KH; Eiymo Mwa Mpollo, MS; Inagami, T; Malik, P; Rai, P; Rizvi, T; Roy, S; Shanmukhappa, SK; VandenHeuvel, K	1
Akbari, H; Asadikaram, G; Ebrahimi, G; Ebrahimi, N; Jafari, A; Masoumi, M; Nazari-Robati, M	1
Ebrahimzadeh Bideskan, A; Hosseinian, S; Khajavi Rad, A; Sadeghnia, HR; Samadi Noshahr, Z; Shafei, MN; Shahraki, S; Soukhtanloo, M	1
de Moura Leão, MF; de Oliveira, LFS; Duarte, JA; Machado, MM; Piccoli, JDCE; Sauzen, PD	1
Negandhi, A; Smeda, JS; Stuckless, J; Watson, D	1
Abreu, TP; Caruso-Neves, C; Dal-Cheri, BKA; Henriques, MG; Peruchetti, DB; Pinheiro, AAS; Silva, LS; Silva-Aguiar, RP; Souza, MC; Takiya, CM	1
Chen, Q; Kang, YM; Li, YH; Qiu, Y; Ren, XS; Tong, Y; Wang, JJ; Xiong, XQ; Ye, C; Zang, YH; Zhu, GQ	1
Flores-Monroy, J; Fonseca-Coronado, S; Hernandez-Campos, ME; Lezama-Martinez, D; Martinez-Aguilar, L; Valencia-Hernandez, I	1
Arthur, E; Chen, J; Janda, A; Kwartler, CS; Milewicz, DM; Peters, AM; Wang, S; Zhou, P; Zhou, Z	1
Diniz, LF; Gonçalves, RV; Lia Mazzeti, A; Mendonça, AAS; Novaes, RD; Souza-Silva, TG	1
Das, S; Pandey, KN; Periyasamy, R	1
Agarwal, R; Azis, NA; Ismail, NH; Ismail, NM; Kamal, MSA; Radjeni, Z; Singh, HJ	1
Ababei, DC; Bild, V; Bild, W; Ciobică, A; Lefter, RM; Rusu, RN	1
Chen, AD; Chen, Q; Kang, YM; Li, YH; Qiu, Y; Wang, JJ; Ye, C; Zheng, F; Zhu, GQ	1
Diz-Muñoz, A; Freire Valls, A; Imle, A; Liang, J; Lu, J; Muley, T; Radhakrishnan, P; Ruiz de Almodovar, C; Salfenmoser, M; Schleussner, N; Schmidt, T; Schneider, M; Shen, Y; Wang, G; Wang, X; Wirsik, NM	1
Gao, X; Ge, X; Jin, F; Li, S; Li, Y; Mao, N; Wei, Z; Xu, H; Yang, F; Yang, Y; Zhang, M; Zhang, Y	1
Andrade, CAF; De Luca, LA; Menani, JV; Pereira, ED; Possari, J; Zenatti, AA	1
Cho, JM; Fu, Z; Hu, J; Liu, X; Lu, A; Lu, X; Su, J; Symons, JD; Wang, F; Yang, T; Zou, CJ	1
Andrade, CAF; Andrade-Franzé, GMF; De Luca, LA; Faria, AM; Menani, JV; Pereira, ED	1
Abeyat, H; Behmanesh, MA; Poormoosavi, SM; Sangtarash, E	1
Bovée, DM; Clahsen-van Groningen, MC; Danser, AHJ; Domenig, O; Foster, D; Garrelds, IM; Hoorn, EJ; Huang, S; Kim, JB; Lu, X; Melton, L; Poglitsch, M; Ren, L; Uijl, E; van Veghel, R; Zlatev, I	1
Djerada, Z	1
Akbar Nekooeian, A; Dehghani, F; Esmaeilpour, T; Mashghoolozekr, E; Rasti Pour, A	1
Del Valle-Mondragón, L; Gallardo-Ortíz, IA; Montes, S; Oros-González, A; Páez-Martínez, N	1
Barretto-de-Souza, L; Crestani, CC; Duarte, JO; Gomes-de-Souza, L; Santana, FG	1
Corrêa, BSG; da Silva, AA; de Barros, S; Furukawa, LNS; Peres, MA; Uchiyama, MK; Vaz, JB	1
Kozyreva, TV; Voronova, IP	1

Reviews

19 review(s) available for losartan and captopril

Article	Year
Protease inhibitors: current status and future prospects. Journal of medicinal chemistry, 2000, Feb-10, Volume: 43, Issue:3 Topics: Animals; Aspartic Acid Endopeptidases; Cysteine Endopeptidases; Cysteine Proteinase Inhibitors; Humans; Metalloendopeptidases; Models, Molecular; Protease Inhibitors; Serine Endopeptidases; Serine Proteinase Inhibitors	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Pathophysiological function of angiotensin II AT1 and AT2 receptors and clinical application of AT1 antagonists]. Nihon rinsho. Japanese journal of clinical medicine, 1998, Volume: 56, Issue:7 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Calcium; Captopril; Cardiovascular System; Clinical Trials as Topic; Heart Failure; Humans; Kidney; Losartan; Protein Kinase C; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction	1998
[ACE inhibitors or AT1 receptor antagonists?]. Deutsche medizinische Wochenschrift (1946), 1999, Sep-24, Volume: 124 Suppl 2 Topics: Age Factors; Aged; Angiotensin I; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Captopril; Clinical Trials as Topic; Death, Sudden, Cardiac; Enalapril; Heart Failure; Humans; Losartan; Prodrugs; Prognosis; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Time Factors	1999
Is there an advantage to combination therapy with ACE inhibitors and angiotensin II-receptor blockers? Cleveland Clinic journal of medicine, 2000, Volume: 67, Issue:2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Hypertension; Losartan	2000
[Angiotensin-II-receptor antagonists for cardiac insufficiency]. Der Internist, 2000, Volume: 41, Issue:9 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Captopril; Dose-Response Relationship, Drug; Drug Therapy, Combination; Heart Failure; Humans; Losartan; Randomized Controlled Trials as Topic; Tetrazoles	2000
Angiotensin receptor blockers and aldosterone antagonists in chronic heart failure. Cardiology clinics, 2001, Volume: 19, Issue:2 Topics: Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Heart Failure; Humans; Hypertension; Losartan; Mineralocorticoid Receptor Antagonists; Renin-Angiotensin System; Spironolactone; Tetrazoles; Valine; Valsartan	2001
[Review of randomized trials of angiotensin receptor blockers in the treatment of patients with congestive heart failure]. Nihon rinsho. Japanese journal of clinical medicine, 2001, Volume: 59, Issue:10 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Captopril; Drug Therapy, Combination; Heart Failure; Humans; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan	2001
Angiotensin blockade in type 2 diabetes: what the new evidence tells us about renal and cardiac complications. The Canadian journal of cardiology, 2002, Volume: 18 Suppl A Topics: Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Captopril; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Humans; Irbesartan; Kidney Diseases; Losartan; Prognosis; Ramipril; Tetrazoles	2002
[What is a good marker for better antihypertensive therapy in diabetic patients when coexisting with hypertension]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 9 Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Biphenyl Compounds; Captopril; Cardiomegaly; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetic Retinopathy; Humans; Hypertension; Irbesartan; Kidney Diseases; Losartan; Practice Guidelines as Topic; Risk; Tetrazoles	2002
[Acute myocardial infarction]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60, Issue:10 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Coronary Restenosis; Female; Humans; Losartan; Male; Middle Aged; Myocardial Infarction; Tetrazoles; Valine; Valsartan	2002
[Evidence for the benefits of ACE inhibitors and AII antagonists in slowing progressive renal failure in diabetes]. Nihon rinsho. Japanese journal of clinical medicine, 2002, Volume: 60 Suppl 10 Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Captopril; Clinical Trials as Topic; Disease Progression; Humans; Irbesartan; Kidney Failure, Chronic; Losartan; Tetrazoles; Treatment Outcome	2002
Treatment of hypertension and prevention of ischemic stroke. Current cardiology reports, 2004, Volume: 6, Issue:2 Topics: Algorithms; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Diltiazem; Humans; Hypertension; Losartan; Perindopril; Stroke	2004
[Treatment of hypertensive patients with impaired glucose tolerance (IGT)]. Nihon rinsho. Japanese journal of clinical medicine, 2005, Volume: 63 Suppl 2 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteriosclerosis; Calcium Channel Blockers; Captopril; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Mellitus; Glucose Intolerance; Humans; Hypertension; Insulin Resistance; Life Style; Losartan; Nifedipine; Risk	2005
A review of the current evidence for the use of angiotensin-receptor blockers in chronic heart failure. International journal of clinical practice, 2005, Volume: 59, Issue:5 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Captopril; Drug Therapy, Combination; Drug Tolerance; Heart Failure; Humans; Losartan; Tetrazoles; Treatment Outcome; Valine; Valsartan	2005
Diabetic nephropathy. Clinical evidence, 2004, Issue:12 Topics: Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Blood Glucose; Captopril; Diabetic Nephropathies; Humans; Irbesartan; Losartan; Tetrazoles	2004
Update on the efficacy of angiotensin receptor blockers in treatment of hypertension. The American journal of managed care, 2005, Volume: 11, Issue:13 Suppl Topics: Angiotensin Receptor Antagonists; Antihypertensive Agents; Captopril; Diabetes Complications; Drug Evaluation; Humans; Hypertension; Losartan; Tetrazoles; Treatment Outcome; Valine; Valsartan	2005
[Clinical trials of ACE inhibitors and ARB for treatment of patients with hypertension, heart failure, and diabetic nephropathy in Japan--special reference to the dosage schedule and adverse effects]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 2008, Volume: 131, Issue:3 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Biphenyl Compounds; Captopril; Cough; Diabetic Nephropathies; Heart Failure; Humans; Hypertension; Japan; Losartan; Randomized Controlled Trials as Topic; Tetrazoles	2008
Could angiotensin-modulating drugs be relevant for the treatment of Trypanosoma cruzi infection? A systematic review of preclinical and clinical evidence. Parasitology, 2019, Volume: 146, Issue:7 Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Captopril; CD8-Positive T-Lymphocytes; Chagas Cardiomyopathy; Chagas Disease; Clinical Studies as Topic; Cytokines; Drug Evaluation, Preclinical; Enalapril; Humans; Losartan; Mice; Trypanosoma cruzi	2019

Trials

42 trial(s) available for losartan and captopril

Article	Year
Randomised trial of losartan versus captopril in patients over 65 with heart failure (Evaluation of Losartan in the Elderly Study, ELITE) Lancet (London, England), 1997, Mar-15, Volume: 349, Issue:9054 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Captopril; Creatinine; Double-Blind Method; Female; Heart Failure; Hospitalization; Humans; Imidazoles; Kidney; Losartan; Male; Mortality; Prospective Studies; Stroke Volume; Survival Analysis; Tetrazoles	1997
Captopril plus losartan in early post-infarction. Neurohormonal effects: a pilot study. Giornale italiano di cardiologia, 1997, Volume: 27, Issue:12 Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Drug Therapy, Combination; Female; Humans; Losartan; Male; Middle Aged; Myocardial Infarction; Norepinephrine; Pilot Projects; Single-Blind Method; Time Factors	1997
A randomized, double-blind comparison of the antihypertensive efficacy and safety of once-daily losartan compared to twice-daily captopril in mild to moderate essential hypertension. Acta cardiologica, 1997, Volume: 52, Issue:6 Topics: Antihypertensive Agents; Blood Pressure; Captopril; Double-Blind Method; Drug Administration Schedule; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Single-Blind Method; Time Factors; Treatment Outcome	1997
Safety, tolerability, and neurohormonal changes of the combination captopril plus losartan in the early postinfarction period: a pilot study. Cardiovascular drugs and therapy, 1998, Volume: 12, Issue:2 Topics: Acute Disease; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Humans; Losartan; Male; Middle Aged; Myocardial Infarction; Myocardial Reperfusion; Neurotransmitter Agents; Pilot Projects; Single-Blind Method	1998
The ELITE study. Evaluation of Losartan in the Elderly Study. British journal of clinical pharmacology, 1998, Volume: 45, Issue:6 Topics: Adult; Angiotensin Receptor Antagonists; Antihypertensive Agents; Captopril; Creatine; Cross-Over Studies; Electrocardiography; Heart; Humans; Losartan; Male; Tetrazoles; Valine; Valsartan	1998
Start of therapy with the angiotensin II antagonist losartan after immediate switch from pretreatment with an ACE inhibitor. British journal of clinical pharmacology, 1998, Volume: 46, Issue:2 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Captopril; Double-Blind Method; Female; Headache; Humans; Hypertension; Losartan; Male	1998
Effect of bradykinin-receptor blockade on the response to angiotensin-converting-enzyme inhibitor in normotensive and hypertensive subjects. The New England journal of medicine, 1998, Oct-29, Volume: 339, Issue:18 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diet, Sodium-Restricted; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypertension; Kidney; Losartan; Male; Reference Values; Renin-Angiotensin System; Single-Blind Method	1998
Usefulness of losartan, captopril, and furosemide in preventing nitrate tolerance and improving control of unstable angina pectoris. The American journal of cardiology, 1998, Nov-01, Volume: 82, Issue:9 Topics: Adult; Aged; Angina, Unstable; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Diuretics; Drug Therapy, Combination; Drug Tolerance; Female; Furosemide; Humans; Isosorbide Dinitrate; Losartan; Male; Middle Aged; Prospective Studies	1998
Angiotensin-converting enzyme inhibitors but not angiotensin II AT 1 receptor antagonists affect erythropoiesis in patients with anemia of end-stage renal disease. Nephron, 1999, Volume: 81, Issue:1 Topics: Anemia; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Erythropoiesis; Female; Humans; Kidney Failure, Chronic; Losartan; Male; Middle Aged	1999
Does the addition of losartan improve the beneficial effects of ACE inhibitors in patients with anterior myocardial infarction? A pilot study. Heart (British Cardiac Society), 1999, Volume: 81, Issue:6 Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Antihypertensive Agents; Blood Pressure; Captopril; Drug Therapy, Combination; Female; Follow-Up Studies; Hemodynamics; Humans; Losartan; Male; Middle Aged; Myocardial Infarction; Norepinephrine; Pilot Projects; Single-Blind Method	1999
Effects of losartan versus captopril on mortality in patients with symptomatic heart failure: rationale, design, and baseline characteristics of patients in the Losartan Heart Failure Survival Study--ELITE II. Journal of cardiac failure, 1999, Volume: 5, Issue:2 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Captopril; Cause of Death; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Heart Failure; Humans; Losartan; Male; Middle Aged; Research Design; Severity of Illness Index; Survival Analysis; Treatment Outcome	1999
Effects of losartan and captopril on QT dispersion in elderly patients with heart failure. ELITE study group. Lancet (London, England), 1999, Jul-31, Volume: 354, Issue:9176 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Captopril; Cardiotonic Agents; Death, Sudden, Cardiac; Electrocardiography; Heart Failure; Humans; Long QT Syndrome; Losartan; Survival Rate; Treatment Outcome	1999
A randomized, double-blind, parallel study on the safety and antihypertensive efficacy of losartan compared to captopril in patients with mild to moderate hypertension and impaired renal function. Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, 1999, Volume: 14 Suppl 4 Topics: Antihypertensive Agents; Captopril; Double-Blind Method; Humans; Hypertension; Losartan; Middle Aged; Renal Insufficiency	1999
Blood pressure and renin angiotensin system responses to initiation of treatment with captopril or losartan in heart failure. British journal of clinical pharmacology, 1999, Volume: 48, Issue:3 Topics: Aged; Aged, 80 and over; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Blood Pressure; Captopril; Cardiac Output, Low; Double-Blind Method; Female; Humans; Losartan; Male; Renin-Angiotensin System	1999
ACE inhibitors still the drug of choice for heart failure--and more. Lancet (London, England), 1999, Nov-20, Volume: 354, Issue:9192 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Death, Sudden, Cardiac; Heart Failure; Humans; Losartan	1999
Angiotensin II increases erythropoietin production in healthy human volunteers. European journal of clinical investigation, 1999, Volume: 29, Issue:10 Topics: Adult; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Erythropoietin; Heart Rate; Hematocrit; Hemoglobins; Hemorrhage; Humans; Infusions, Intravenous; Losartan; Male; Phlebotomy; Placebos	1999
A comparison of intervention with losartan or captopril in acute myocardial infarction. European journal of heart failure, 2000, Volume: 2, Issue:1 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Double-Blind Method; Female; Hemodynamics; Humans; Losartan; Male; Middle Aged; Myocardial Infarction; Prospective Studies; Ultrasonography; Ventricular Function, Left	2000
Effect of losartan compared with captopril on mortality in patients with symptomatic heart failure: randomised trial--the Losartan Heart Failure Survival Study ELITE II. Lancet (London, England), 2000, May-06, Volume: 355, Issue:9215 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Double-Blind Method; Female; Heart Failure; Humans; Losartan; Male; Middle Aged; Survival Analysis	2000
Effects of losartan and captopril on left ventricular volumes in elderly patients with heart failure: results of the ELITE ventricular function substudy. American heart journal, 2000, Volume: 139, Issue:6 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Captopril; Cardiac Volume; Double-Blind Method; Female; Heart Failure; Humans; Losartan; Male; Myocardial Contraction; Radionuclide Ventriculography; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Stroke Volume; Treatment Outcome; Ventricular Function, Left; Ventricular Remodeling	2000
[A-II blocker or ACE inhibitor in heart failure? Captopril can't be beat]. MMW Fortschritte der Medizin, 1999, Nov-25, Volume: 141, Issue:47 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Female; Heart Failure; Humans; Losartan; Male; Survival Rate; Treatment Outcome	1999
[Interview with the author of ELITE II. Cave: small studies of fatal illnesses]. MMW Fortschritte der Medizin, 1999, Nov-25, Volume: 141, Issue:47 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Female; Heart Failure; Humans; Losartan; Male; Survival Rate	1999
Haemodynamic, neurohumoral and exercise effects of losartan vs. captopril in chronic heart failure: results of an ELITE trial substudy. Evaluation of Losartan in the Elderly. European journal of heart failure, 1999, Volume: 1, Issue:4 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Captopril; Chronic Disease; Double-Blind Method; Exercise Test; Exercise Tolerance; Female; Heart Failure; Hemodynamics; Humans; Losartan; Male; Neurotransmitter Agents; Norepinephrine; Renin	1999
Is losartan superior to captopril in reducing all-cause mortality in elderly patients with symptomatic heart failure? The Journal of family practice, 2000, Volume: 49, Issue:8 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Double-Blind Method; Female; Heart Failure; Humans; Losartan; Male; Middle Aged; Prospective Studies	2000
Effect of indomethacin on blood pressure lowering by captopril and losartan in hypertensive patients. Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:3 Topics: Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Blood Pressure; Captopril; Cardiovascular Agents; Circadian Rhythm; Drug Interactions; Female; Humans; Indomethacin; Losartan; Male; Middle Aged	2000
[The ELITE 2 study]. Presse medicale (Paris, France : 1983), 2000, Sep-09, Volume: 29, Issue:25 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Double-Blind Method; Follow-Up Studies; Heart Failure; Humans; Losartan; Middle Aged; Prospective Studies; Time Factors	2000
First dose hypotension after angiotensin converting enzyme inhibitor captopril and angiotensin II blocker losartan in patients with acute myocardial infarction. International journal of cardiology, 2000, Sep-15, Volume: 75, Issue:2-3 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Captopril; Female; Humans; Hypotension; Losartan; Male; Middle Aged; Myocardial Infarction; Prospective Studies	2000
Randomised comparison of losartan vs. captopril on quality of life in elderly patients with symptomatic heart failure: the losartan heart failure ELITE quality of life substudy. Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2000, Volume: 9, Issue:4 Topics: Aged; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Captopril; Double-Blind Method; Female; Heart Failure; Humans; Losartan; Male; Quality of Life	2000
Comparison of baseline data, initial course, and management: losartan versus captopril following acute myocardial infarction (The OPTIMAAL Trial). OPTIMAAL Trial Steering Committee and Investigators. Optimal Trial in Myocardial Infarction with the Angiote The American journal of cardiology, 2001, Mar-15, Volume: 87, Issue:6 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Heart Failure; Humans; Losartan; Male; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic; Risk Factors; Survival Rate	2001
Effects of losartan and captopril on mortality and morbidity in high-risk patients after acute myocardial infarction: the OPTIMAAL randomised trial. Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan. Lancet (London, England), 2002, Sep-07, Volume: 360, Issue:9335 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Endpoint Determination; Female; Humans; Losartan; Male; Middle Aged; Morbidity; Myocardial Infarction; Risk Factors	2002
ACE inhibitors or AT-1 antagonists - which is OPTIMAAL after acute myocardial infarction? Expert opinion on pharmacotherapy, 2003, Volume: 4, Issue:3 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Losartan; Male; Myocardial Infarction; Receptor, Angiotensin, Type 1; Research Design; Risk Assessment	2003
Prospective evaluation comparing the effects of enalapril and losartan in left ventricular remodeling after acute myocardial infarction. American heart journal, 2003, Volume: 145, Issue:6 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Enalapril; Female; Humans; Losartan; Male; Middle Aged; Myocardial Infarction; Radionuclide Ventriculography; Stroke Volume; Ventricular Function, Left; Ventricular Remodeling	2003
Effects of losartan and captopril on left ventricular systolic and diastolic function after acute myocardial infarction: results of the Optimal Trial in Myocardial Infarction with Angiotensin II Antagonist Losartan (OPTIMAAL) echocardiographic substudy. American heart journal, 2004, Volume: 147, Issue:3 Topics: Aged; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Captopril; Double-Blind Method; Echocardiography; Electrocardiography; Female; Humans; Losartan; Male; Middle Aged; Myocardial Infarction; Ventricular Function, Left	2004
Prognostic risk of atrial fibrillation in acute myocardial infarction complicated by left ventricular dysfunction: the OPTIMAAL experience. European heart journal, 2005, Volume: 26, Issue:4 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Atrial Fibrillation; Captopril; Epidemiologic Methods; Female; Humans; Losartan; Male; Middle Aged; Myocardial Infarction; Prognosis; Stroke; Ventricular Dysfunction, Left	2005
Soluble CD40 ligand in acute and chronic heart failure. European heart journal, 2005, Volume: 26, Issue:11 Topics: Acute Disease; Adult; Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Captopril; CD40 Ligand; Chronic Disease; Female; Heart Failure; Humans; Losartan; Male; Middle Aged; Myocardial Infarction; Treatment Outcome	2005
Losartan renography for the detection of renal artery stenosis: comparison with captopril renography and evaluation of dose and timing. European journal of nuclear medicine and molecular imaging, 2005, Volume: 32, Issue:9 Topics: Adolescent; Adult; Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Humans; Losartan; Male; Middle Aged; Radioisotope Renography; Renal Artery Obstruction; Reproducibility of Results; Sensitivity and Specificity	2005
Comparison of losartan and captopril on heart failure-related outcomes and symptoms from the losartan heart failure survival study (ELITE II). American heart journal, 2005, Volume: 150, Issue:1 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Heart Failure; Humans; Losartan; Male; Survival	2005
Lipid peroxidation is not increased in heart failure patients on modern pharmacological therapy. International journal of cardiology, 2006, Oct-10, Volume: 112, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Atrial Natriuretic Factor; Captopril; Comorbidity; Delayed-Action Preparations; Dinoprost; Female; Heart Failure; Hemodynamics; Humans; Isosorbide Dinitrate; Lipid Peroxidation; Losartan; Male; Malondialdehyde; Middle Aged; Myocardial Infarction; Natriuretic Peptide, Brain; Nitric Oxide Donors; Oxidative Stress; Ramipril; Stroke Volume; Ultrasonography; Ventricular Dysfunction, Left	2006
Comparison of home and office blood pressure in hypertensive patients treated with zofenopril or losartan. Blood pressure. Supplement, 2007, Volume: 2 Topics: Aged; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Captopril; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Office Visits	2007
Plasma MMP-2, MMP-9 and N-BNP in long-term survivors following complicated myocardial infarction: relation to cardiac magnetic resonance imaging measures of left ventricular structure and function. Journal of cardiac failure, 2007, Volume: 13, Issue:10 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Biomarkers; Captopril; Enzyme-Linked Immunosorbent Assay; Female; Follow-Up Studies; Heart Ventricles; Humans; Losartan; Magnetic Resonance Imaging; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Myocardial Infarction; Natriuretic Peptide, Brain; Peptide Fragments; Prognosis; Severity of Illness Index; Stroke Volume; Time Factors; Ventricular Function, Left; Ventricular Remodeling	2007
Antihypertensive efficacy and tolerability of once daily losartan potassium compared with captopril in patients with mild to moderate essential hypertension. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1995, Volume: 13, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Double-Blind Method; Female; Headache; Humans; Hypertension; Losartan; Male; Middle Aged	1995
Angiotensin II, independent of plasma renin activity, contributes to the hypertension of autonomic failure. Hypertension (Dallas, Tex. : 1979), 2013, Volume: 61, Issue:3 Topics: Aged; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Captopril; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Orthostatic Intolerance; Pure Autonomic Failure; Renin; Sodium	2013
Acute effects of angiotensin-converting enzyme inhibition versus angiotensin II receptor blockade on cardiac sympathetic activity in patients with heart failure. American journal of physiology. Regulatory, integrative and comparative physiology, 2017, Oct-01, Volume: 313, Issue:4 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Heart; Heart Failure; Hemodynamics; Humans; Losartan; Male; Middle Aged; Renin-Angiotensin System; Sympathetic Nervous System; Treatment Outcome	2017

Other Studies

340 other study(ies) available for losartan and captopril

Article	Year
Interaction of digoxin with antihypertensive drugs via MDR1. Life sciences, 2002, Feb-15, Volume: 70, Issue:13 Topics: Animals; Antihypertensive Agents; ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Cells, Cultured; Digoxin; Drug Interactions; Humans; Time Factors	2002
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling. Current drug discovery technologies, 2004, Volume: 1, Issue:4 Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration	2004
New NO-releasing pharmacodynamic hybrids of losartan and its active metabolite: design, synthesis, and biopharmacological properties. Journal of medicinal chemistry, 2006, Apr-20, Volume: 49, Issue:8 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Drug Design; Drug Evaluation, Preclinical; Hypertension; In Vitro Techniques; Losartan; Male; Molecular Structure; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Structure-Activity Relationship; Time Factors	2006
Synthesis and antihypertensive effects of new methylthiomorpholinphenol derivatives. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Animals; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Design; Heart Rate; Morpholines; Phenols; Rats	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species. Chemical research in toxicology, 2010, Volume: 23, Issue:1 Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship	2010
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Developing structure-activity relationships for the prediction of hepatotoxicity. Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes	2010
Antihypertensive and antiarrhythmic properties of a para-hydroxy[bis(ortho-morpholinylmethyl)]phenyl-1,4-DHP compound: comparison with other compounds of the same kind and relationship with logP values. European journal of medicinal chemistry, 2010, Volume: 45, Issue:10 Topics: Animals; Anti-Arrhythmia Agents; Antihypertensive Agents; Blood Pressure; Dihydropyridines; Heart Rate; Male; Morpholines; Rats; Rats, Wistar; Spectrophotometry, Ultraviolet	2010
A predictive ligand-based Bayesian model for human drug-induced liver injury. Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12 Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands	2010
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology. Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3 Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries	2023
Effect of DuP 753, a nonpeptide angiotensin II receptor antagonist, on the drinking responses to acutely administered dipsogenic agents in rats. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1992, Volume: 199, Issue:2 Topics: 5-Hydroxytryptophan; Analysis of Variance; Angiotensin II; Animals; Biphenyl Compounds; Captopril; Dose-Response Relationship, Drug; Drinking; Imidazoles; Injections, Intraventricular; Injections, Subcutaneous; Isoproterenol; Losartan; Male; Polyethylene Glycols; Propranolol; Rats; Rats, Inbred Strains; Receptors, Adrenergic, beta; Saline Solution, Hypertonic; Serotonin; Tetrazoles	1992
Relation between inhibition of renal angiotensin II production and hemodynamic effect of captopril in anesthetized rabbit. Journal of hypertension, 1992, Volume: 10, Issue:8 Topics: Angiotensin I; Angiotensin II; Animals; Biphenyl Compounds; Captopril; Dose-Response Relationship, Drug; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Rabbits; Renal Circulation; Renin-Angiotensin System; Sodium, Dietary; Tetrazoles	1992
Effects of angiotensins on cellular hypertrophy and c-fos expression in cultured arterial smooth muscle cells. European journal of biochemistry, 1992, Jun-01, Volume: 206, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Biphenyl Compounds; Captopril; Cells, Cultured; DNA; Imidazoles; Indoles; Losartan; Muscle, Smooth, Vascular; Oligopeptides; Proto-Oncogene Proteins c-fos; Rats; Rats, Inbred WKY; RNA; Tetrazoles	1992
Stimulation of prolactin secretion from rat pituitary by luteinizing hormone-releasing hormone: evidence against mediation by angiotensin II acting through a (Sar1-Ala8)-angiotensin II-sensitive receptor. Neuroendocrinology, 1992, Volume: 56, Issue:2 Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensinogen; Animals; Biphenyl Compounds; Captopril; Cells, Cultured; Female; Gonadotropin-Releasing Hormone; Imidazoles; Losartan; Male; Pituitary Gland; Prolactin; Rats; Rats, Wistar; Receptors, Angiotensin; Saralasin; Tetrazoles	1992
Chronic captopril and losartan (DuP 753) administration in rats with high-output heart failure. The American journal of physiology, 1992, Volume: 263, Issue:3 Pt 2 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Biphenyl Compounds; Body Fluids; Captopril; Cardiac Output, High; Cardiomegaly; Hemodynamics; Homeostasis; Imidazoles; Losartan; Male; Myocardium; Organ Size; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles; Time Factors	1992
Effect of captopril and the nonpeptide angiotensin II antagonists, SK&F 108566 and EXP3174, on renal function in dogs with a renal artery stenosis. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 263, Issue:2 Topics: Acrylates; Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Dose-Response Relationship, Drug; Female; Glomerular Filtration Rate; Imidazoles; Inulin; Kidney; Losartan; Regional Blood Flow; Renal Artery Obstruction; Tetrazoles; Thiophenes	1992
The antihypertensive effect of the angiotensin II receptor antagonist DuP 753 may not be due solely to angiotensin II receptor antagonism. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 262, Issue:2 Topics: Acrylates; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Decerebrate State; Enalapril; Imidazoles; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred Strains; Receptors, Angiotensin; Spinal Cord; Tetrazoles; Thiophenes	1992
Angiotensin II and renal functional reserve in rats with Goldblatt hypertension. Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:6 Pt 2 Topics: Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Glycine; Hemodynamics; Hypertension, Renovascular; Imidazoles; Injections; Kidney; Kidney Glomerulus; Losartan; Male; Punctures; Rats; Rats, Inbred Strains; Tetrazoles	1992
Angiotensin II receptor antagonism in ovine heart failure: acute hemodynamic, hormonal, and renal effects. The American journal of physiology, 1992, Volume: 263, Issue:1 Pt 2 Topics: Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Captopril; Cardiac Output, Low; Female; Hemodynamics; Hormones; Imidazoles; Kidney; Losartan; Sheep; Tetrazoles	1992
Effect of an angiotensin II and a kinin receptor antagonist on the renal hemodynamic response to captopril. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:6 Pt 2 Topics: Angiotensin II; Animals; Bradykinin; Captopril; Hemodynamics; Imidazoles; Kinins; Lasers; Losartan; Punctures; Rats; Rats, Inbred Strains; Receptors, Bradykinin; Receptors, Neurotransmitter; Renal Circulation; Tetrazoles; Ultrasonography	1991
In vivo evaluation of the antagonist activity of angiotensin I analogs. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 260, Issue:1 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensins; Animals; Biphenyl Compounds; Captopril; Imidazoles; Losartan; Lung; Male; Peptide Fragments; Rats; Rats, Inbred Strains; Tetrazoles	1992
Kinins, nitric oxide, and the hypotensive effect of captopril and ramiprilat in hypertension. Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arginine; Biphenyl Compounds; Blood Pressure; Captopril; Hypertension; Imidazoles; Kinins; Losartan; Male; Nitric Oxide; omega-N-Methylarginine; Pyrroles; Ramipril; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles	1992
Nonpeptide angiotensin II receptor antagonists. Studies with DuP 753 and EXP3174 in dogs. European journal of pharmacology, 1991, Sep-24, Volume: 202, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Captopril; Dogs; Female; Furosemide; Imidazoles; Kidney; Kidney Function Tests; Losartan; Male; Pyridines; Radioimmunoassay; Renin-Angiotensin System; Tetrazoles	1991
Kinin contribution to renal vasodilator effect of captopril in rabbit. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bradykinin; Captopril; Imidazoles; Kidney; Losartan; Rabbits; Receptors, Bradykinin; Receptors, Neurotransmitter; Renal Circulation; Saralasin; Tetrazoles; Vasodilation	1991
Effects of DuP 753 on proximal nephron and renal transport. American journal of hypertension, 1991, Volume: 4, Issue:4 Pt 2 Topics: Angiotensin II; Animals; Biological Transport; Body Fluids; Captopril; Electrolytes; Imidazoles; Kidney; Kidney Tubules; Losartan; Male; Nephrons; Perfusion; Punctures; Rats; Rats, Inbred Strains; Tetrazoles	1991
Hemodynamic effects of direct angiotensin II blockade compared to converting enzyme inhibition in rat model of heart failure. American journal of hypertension, 1991, Volume: 4, Issue:4 Pt 2 Topics: Administration, Oral; Angiotensin II; Animals; Body Weight; Captopril; Cardiac Output, Low; Compliance; Disease Models, Animal; Dose-Response Relationship, Drug; Heart; Hemodynamics; Imidazoles; Losartan; Male; Myocardial Infarction; Rats; Rats, Inbred Strains; Tetrazoles; Ventricular Function, Left	1991
Haemodynamic effects of human alpha-calcitonin gene-related peptide following administration of endothelin-1 or NG-nitro-L-arginine methyl ester in conscious rats. British journal of pharmacology, 1991, Volume: 103, Issue:1 Topics: Angiotensin II; Animals; Arginine; Biphenyl Compounds; Blood Pressure; Calcitonin Gene-Related Peptide; Captopril; Endothelins; Heart Rate; Hemodynamics; Hindlimb; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitroarginine; Rats; Regional Blood Flow; Renal Circulation; Splanchnic Circulation; Tetrazoles; Vasoconstriction	1991
Differential regional haemodynamic effects of the non-peptide angiotensin II antagonist, DuP 753, in water-replete and water-deprived Brattleboro rats. Life sciences, 1991, Volume: 48, Issue:8 Topics: Angiotensin II; Animals; Captopril; Drinking; Hemodynamics; Imidazoles; Leg; Losartan; Male; Rats; Rats, Brattleboro; Regional Blood Flow; Tetrazoles; Vasodilation	1991
Effect of angiotensin II antagonism on canine renal sympathetic nerve function. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:6 Pt 2 Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Dogs; Electric Stimulation; Female; Imidazoles; Kidney; Losartan; Male; Norepinephrine; Pyridines; Saralasin; Sympathetic Nervous System; Tetrazoles; Vascular Resistance; Vasoconstriction	1991
Hypotensive action of DuP 753, an angiotensin II antagonist, in spontaneously hypertensive rats. Nonpeptide angiotensin II receptor antagonists: X. Hypertension (Dallas, Tex. : 1979), 1990, Volume: 15, Issue:5 Topics: Administration, Oral; Angiotensin II; Animals; Antihypertensive Agents; Azoles; Captopril; Furosemide; Imidazoles; Injections, Intravenous; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles	1990
Proximal nephron and renal effects of DuP 753, a nonpeptide angiotensin II receptor antagonist. Kidney international, 1990, Volume: 38, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Captopril; Diuretics; Imidazoles; Kidney Tubules, Proximal; Losartan; Male; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Tetrazoles	1990
Efficacy of angiotensin-converting enzyme inhibition and AT1 receptor blockade on cardiac pump performance after myocardial infarction in rats. Journal of cardiovascular pharmacology, 1994, Volume: 23, Issue:4 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Captopril; Heart; Heart Rate; Imidazoles; Losartan; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Tetrazoles	1994
Angiotensin II maintains, but does not mediate, isoproterenol-induced cardiac hypertrophy in rats. The American journal of physiology, 1994, Volume: 267, Issue:4 Pt 2 Topics: Actins; Angiotensin II; Animals; Base Sequence; Biphenyl Compounds; Blood Pressure; Captopril; Cardiomegaly; DNA; DNA Primers; Dose-Response Relationship, Drug; Gene Expression; Genes, fos; Heart; Hydralazine; Hydroxyproline; Imidazoles; Isoproterenol; Labetalol; Losartan; Male; Methyldopa; Molecular Sequence Data; Myocardium; Myosins; Polymerase Chain Reaction; Rats; Rats, Sprague-Dawley; RNA; RNA, Messenger; Tetrazoles; Transcription, Genetic	1994
[Effects of chronic losartan treatment on myocardial, vascular structure and reactivity with aging in spontaneously hypertensive rats (SHR): its effects compared with those of captopril]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1995, Volume: 105, Issue:6 Topics: Aging; Animals; Antihypertensive Agents; Arteriosclerosis; Biphenyl Compounds; Captopril; Coronary Circulation; Coronary Vessels; Heart Ventricles; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Male; Mesenteric Arteries; Organ Size; Rats; Rats, Inbred SHR; Tetrazoles; Vasoconstriction	1995
The effects of losartan and captopril on vasopressor actions of cirazoline in the absence and presence of SZL-49 and nifedipine. Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:1 Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Analysis of Variance; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Captopril; Decerebrate State; Dose-Response Relationship, Drug; Imidazoles; Infusions, Intra-Arterial; Infusions, Intravenous; Losartan; Male; Nifedipine; Prazosin; Rats; Rats, Sprague-Dawley; Tetrazoles; Vasoconstriction; Vasodilator Agents	1995
Comparative effects of losartan, captopril, and enalapril on murine acute myocarditis due to encephalomyocarditis virus. Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:1 Topics: Acute Disease; Administration, Oral; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Body Weight; Captopril; Cardiovirus Infections; Enalapril; Encephalomyocarditis virus; Female; Heart; Heart Failure; Hypertrophy, Left Ventricular; Imidazoles; Injections, Intraperitoneal; Losartan; Mice; Mice, Inbred C3H; Myocarditis; Myocardium; Organ Size; Random Allocation; Tetrazoles; Therapeutic Equivalency	1995
Losartan improves baroreflex control of heart rate of coarcted hypertensive rats. The American journal of physiology, 1995, Volume: 269, Issue:3 Pt 2 Topics: Administration, Oral; Animals; Antihypertensive Agents; Aortic Coarctation; Baroreflex; Biphenyl Compounds; Blood Pressure; Captopril; Heart Rate; Hypertension; Imidazoles; Infusions, Intravenous; Injections, Intraventricular; Losartan; Male; Nephrectomy; Rats; Rats, Wistar; Receptors, Angiotensin; Tetrazoles	1995
Comparison of the transplacental transfer of enalapril, captopril and losartan in sheep. British journal of pharmacology, 1995, Volume: 114, Issue:7 Topics: Angiotensin I; Angiotensin Receptor Antagonists; Animals; Biological Transport; Biphenyl Compounds; Blood Pressure; Captopril; Enalapril; Female; Fetus; Imidazoles; Injections, Intravenous; Losartan; Placenta; Sheep; Tetrazoles	1995
Chronic effect of losartan in a murine model of dilated cardiomyopathy: comparison with captopril. The Journal of pharmacology and experimental therapeutics, 1995, Volume: 273, Issue:2 Topics: Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Captopril; Cardiomyopathy, Dilated; Disease Models, Animal; Female; Imidazoles; Losartan; Mice; Mice, Inbred DBA; Organ Size; Tetrazoles	1995
Antihypertensive and renal-protective effects of losartan in streptozotocin diabetic rats. Journal of hypertension, 1995, Volume: 13, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Captopril; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Glomerulosclerosis, Focal Segmental; Hypertension; Imidazoles; Kidney; Losartan; Male; Organ Size; Random Allocation; Rats; Rats, Inbred SHR; Tetrazoles	1995
Involvement of renin-angiotensin system in the reduced pressure natriuresis response of hyperthyroid rats. The American journal of physiology, 1995, Volume: 268, Issue:5 Pt 1 Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Captopril; Diuresis; Glomerular Filtration Rate; Hyperthyroidism; Imidazoles; Losartan; Male; Natriuresis; Rats; Rats, Wistar; Renal Circulation; Renin-Angiotensin System; Tetrazoles	1995
Mechanistic analysis of renal protection by angiotensin converting enzyme inhibitor in Dahl salt-sensitive rats. Journal of hypertension, 1994, Volume: 12, Issue:8 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood; Blood Pressure; Captopril; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Rats; Rats, Inbred Strains; Renin-Angiotensin System; Sodium Chloride; Tetrazoles; Urine	1994
Pharmacological studies of stonefish (Synanceja trachynis) venom. Toxicon : official journal of the International Society on Toxinology, 1994, Volume: 32, Issue:10 Topics: Animals; Biphenyl Compounds; Blood Pressure; Captopril; Chromones; Dose-Response Relationship, Drug; Fish Venoms; Fishes; Guinea Pigs; Heptanoic Acids; Histamine; Ileum; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Male; Mecamylamine; Muscle Contraction; Muscle, Smooth; Phospholipases A; Phospholipases A2; Quinacrine; Rats; Receptors, Thromboxane; Serotonin; SRS-A; Tetrazoles; Vas Deferens	1994
Telemetric blood pressure monitoring in benign 2-kidney, 1-clip renovascular hypertension: effect of chronic caffeine ingestion. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:3 Topics: Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Caffeine; Captopril; Constriction; Heart Rate; Hypertension, Renovascular; Imidazoles; Kidney; Losartan; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Telemetry; Tetrazoles	1994
Regression of cardiac hypertrophy and myosin isoenzyme patterns by losartan and captopril in renovascular hypertensive rats. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1994, Volume: 15, Issue:3 Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Hypertension, Renovascular; Hypertrophy, Left Ventricular; Imidazoles; Losartan; Male; Myocardium; Myosins; Organ Size; Rats; Tetrazoles	1994
ANG II receptor blockade prevents ventricular hypertrophy and ANF gene expression with pressure overload in mice. The American journal of physiology, 1994, Volume: 266, Issue:6 Pt 2 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Atrial Natriuretic Factor; Biphenyl Compounds; Captopril; Cardiomegaly; Constriction; Gene Expression; Heart Ventricles; Hemodynamics; Hypertension; Imidazoles; Losartan; Mice; Mice, Inbred C57BL; Tetrazoles	1994
Effects of the angiotensin II receptor antagonist losartan on herpes simplex virus-type 2 infection of cultured vero and cardiac neonatal myocytes. Life sciences, 1994, Volume: 55, Issue:4 Topics: Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Captopril; Cells, Cultured; Heart; Herpesvirus 2, Human; Imidazoles; L-Lactate Dehydrogenase; Losartan; Myocardium; Rats; Rats, Sprague-Dawley; Tetrazoles; Vero Cells; Viral Plaque Assay	1994
Mechanisms of renal vasoconstriction following furosemide in conscious rats. Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 349, Issue:5 Topics: Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Chlorthalidone; Dose-Response Relationship, Drug; Drug Interactions; Furosemide; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Rats; Rats, Wistar; Regional Blood Flow; Renal Artery; Tetrazoles; Vascular Resistance; Vasoconstriction	1994
Comparison of renal hemodynamic effect of ramiprilat to captopril; possible role of kinins. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:2 Topics: Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Imidazoles; Kidney; Kinins; Losartan; Male; Rabbits; Ramipril; Renal Circulation; Tetrazoles	1994
Renin-angiotensin, arterial blood pressure, and salt appetite in rats. The American journal of physiology, 1994, Volume: 266, Issue:2 Pt 2 Topics: Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Appetite; Biphenyl Compounds; Blood Pressure; Body Weight; Captopril; Creatinine; Furosemide; Imidazoles; Losartan; Male; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sodium; Sodium, Dietary; Tetrazoles; Time Factors; Urine	1994
Angiotensin II-mediated pressor effect of rat joining peptide. The American journal of physiology, 1994, Volume: 266, Issue:3 Pt 2 Topics: Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Imidazoles; Injections, Intravenous; Losartan; Male; Peptide Fragments; Peptides; Pro-Opiomelanocortin; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Sympatholytics; Tetrazoles	1994
Analysis of angiotensins I, II, and III in pulmonary vascular bed of the rat. The American journal of physiology, 1994, Volume: 266, Issue:4 Pt 1 Topics: Angiotensin I; Angiotensin II; Angiotensin III; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Blood Vessels; Captopril; Enalaprilat; Imidazoles; In Vitro Techniques; Losartan; Male; Pulmonary Circulation; Rats; Rats, Sprague-Dawley; Tetrazoles	1994
A facilitatory effect of anti-angiotensin drugs on vagal bradycardia in the pithed rat and guinea-pig. British journal of pharmacology, 1993, Volume: 110, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bronchoconstriction; Captopril; Decerebrate State; Electric Stimulation; Guinea Pigs; Heart; Heart Rate; Imidazoles; In Vitro Techniques; Losartan; Male; Methacholine Compounds; Nephrectomy; Rats; Rats, Sprague-Dawley; Sympathetic Nervous System; Tetrazoles; Tubocurarine; Vagus Nerve	1993
Antihypertensive therapy and adaptive mechanisms in peripheral ischemia. Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:5 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Capillaries; Captopril; Felodipine; Hindlimb; Iliac Artery; Imidazoles; Ischemia; Losartan; Male; Muscle, Smooth, Vascular; Muscles; Rats; Rats, Inbred SHR; Tetrazoles	1993
Angiotensin converting enzyme inhibitors or DuP753 prevent neointimal formation following balloon injury with single topical or multiple systemic application. Biochemical and biophysical research communications, 1993, Oct-29, Volume: 196, Issue:2 Topics: Administration, Topical; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Blood Pressure; Body Weight; Captopril; Carotid Arteries; Carotid Artery Injuries; Catheterization; Cell Division; Embolization, Therapeutic; Imidazoles; Indans; Losartan; Male; Muscle, Smooth, Vascular; Rats; Rats, Wistar; Tetrazoles	1993
DuP 753 is more effective than captopril on baroreceptor function in high-renin hypertension. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:1 Suppl Topics: Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Captopril; Heart Rate; Hypertension; Imidazoles; Losartan; Male; Phenylephrine; Pressoreceptors; Rats; Rats, Wistar; Reflex; Renin; Tetrazoles; Time Factors	1994
Chronic converting enzyme inhibition facilitates baroreceptor resetting to hypertensive levels. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:1 Suppl Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Enalapril; Hypertension; Imidazoles; Losartan; Male; Pressoreceptors; Rats; Rats, Wistar; Reference Values; Regression Analysis; Tetrazoles	1994
Regulation of the urinary excretion of endothelin in the rat. American journal of hypertension, 1993, Volume: 6, Issue:6 Pt 1 Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Arginine Vasopressin; Biphenyl Compounds; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Endothelins; Glomerular Filtration Rate; Imidazoles; Kidney; Losartan; Male; Nifedipine; Radioimmunoassay; Rats; Rats, Wistar; Saralasin; Tetrazoles	1993
Role of intrarenal ANG II in reflex neural stimulation of plasma renin activity and renal sodium reabsorption. The American journal of physiology, 1993, Volume: 265, Issue:2 Pt 2 Topics: Absorption; Angiotensin II; Animals; Biphenyl Compounds; Blood Volume; Captopril; Dogs; Female; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Reflex; Renal Circulation; Renin; Sodium; Sympathetic Nervous System; Tetrazoles; Vasoconstriction	1993
Endogenous angiotensin II modulates the effect of atrial natriuretic peptide on extracellular fluid partition. The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 2 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Atrial Natriuretic Factor; Biphenyl Compounds; Blood Pressure; Captopril; Enalaprilat; Extracellular Space; Hematocrit; Imidazoles; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles	1993
Chimeric renin-angiotensin system demonstrates sustained increase in blood pressure of transgenic mice carrying both human renin and human angiotensinogen genes. The Journal of biological chemistry, 1993, Jun-05, Volume: 268, Issue:16 Topics: Angiotensin I; Angiotensin II; Angiotensinogen; Animals; Biphenyl Compounds; Blood Pressure; Captopril; Dipeptides; Humans; Imidazoles; Losartan; Male; Mice; Mice, Transgenic; Morpholines; Recombinant Proteins; Renin; Renin-Angiotensin System; Tetrazoles	1993
Erythropoietin-induced antinatriuresis mediated by angiotensin II in perfused kidneys. Journal of the American Society of Nephrology : JASN, 1993, Volume: 3, Issue:9 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Captopril; Dose-Response Relationship, Drug; Erythropoietin; Imidazoles; In Vitro Techniques; Kidney; Losartan; Male; Natriuresis; Perfusion; Rats; Rats, Wistar; Tetrazoles	1993
Augmentation of coronary blood flow by ACE inhibition: role of angiotensin and bradykinin. Clinical and experimental hypertension (New York, N.Y. : 1993), 1995, Volume: 17, Issue:7 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Bradykinin; Captopril; Coronary Vessels; Imidazoles; Losartan; Perfusion; Swine; Tetrazoles	1995
Survival after myocardial infarction in rats: captopril versus losartan. Journal of the American College of Cardiology, 1996, Mar-01, Volume: 27, Issue:3 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Confounding Factors, Epidemiologic; Disease Models, Animal; Hemodynamics; Imidazoles; Losartan; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Survival Analysis; Tetrazoles; Time Factors	1996
Comparative studies on differential inhibition of the renin - angiotensin system in the anesthetized guinea pig. Canadian journal of physiology and pharmacology, 1995, Volume: 73, Issue:10 Topics: Alanine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Guinea Pigs; Imidazoles; Losartan; Male; Nephrectomy; Pyridines; Renin; Renin-Angiotensin System; Tetrazoles; Thiazoles	1995
Relative contribution of angiotensin II, bradykinin, and prostaglandins to the renal effects of converting enzyme inhibition in rats after chronic myocardial infarction. Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cyclooxygenase Inhibitors; Hemodynamics; Imidazoles; Indomethacin; Kidney; Kidney Function Tests; Losartan; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Tetrazoles	1996
Renin-angiotensin system in stretch-induced hypertrophy of cultured neonatal rat heart cells. European journal of pharmacology, 1996, Jun-20, Volume: 307, Issue:1 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Cardiomegaly; Cells, Cultured; Heart; Imidazoles; Losartan; Muscle Proteins; Muscle Spindles; Myocardium; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles	1996
Blockade of the renin-angiotensin system in heart failure in conscious dogs. Journal of hypertension, 1995, Volume: 13, Issue:12 Pt 1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding, Competitive; Biphenyl Compounds; Captopril; Dogs; Heart Failure; Hemodynamics; Imidazoles; Losartan; Male; Myocardium; Pyridines; Reference Values; Renin-Angiotensin System; Tetrazoles	1995
Threshold sodium excretory and renal blood flow effects of angiotensin converting enzyme inhibition. Journal of hypertension, 1995, Volume: 13, Issue:12 Pt 1 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Differential Threshold; Diuresis; Hemodynamics; Imidazoles; Losartan; Natriuresis; Nephrectomy; Potassium; Ramipril; Rats; Rats, Wistar; Renal Circulation; Tetrazoles; Vasodilation	1995
The role of brain angiotensin in thirst and AVP release induced by hemorrhage. Regulatory peptides, 1996, Oct-08, Volume: 66, Issue:1-2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Blood Volume; Captopril; Cohort Studies; Colony-Stimulating Factors; Drinking; Hemorrhage; Hypothalamus; Imidazoles; Injections, Intraperitoneal; Injections, Intraventricular; Losartan; Male; Oligopeptides; Radioimmunoassay; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Recombinant Proteins; Tetrazoles; Thirst; Time Factors; Vasopressins	1996
Temporal differences between the involvement of angiotensin II and endothelin in the cardiovascular responses to endotoxaemia in conscious rats. British journal of pharmacology, 1996, Volume: 119, Issue:8 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine Vasopressin; Biphenyl Compounds; Captopril; Endothelins; Endotoxemia; Hemodynamics; Imidazoles; Indans; Lipopolysaccharides; Losartan; Male; Rats; Renal Circulation; Tetrazoles; Vasopressins	1996
The renin angiotensin system and nociception in spontaneously hypertensive rats. Life sciences, 1995, Feb-17, Volume: 56, Issue:13 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Captopril; Hydralazine; Hypertension; Imidazoles; Losartan; Male; Motor Activity; Nociceptors; Pain Measurement; Pain Threshold; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Tetrazoles	1995
Effect of captopril and losartan on blood pressure and accumulation of LDL and fibrinogen by aortic wall and other tissues in normotensive and hypertensive rats. Journal of cardiovascular pharmacology, 1997, Volume: 29, Issue:1 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Captopril; Fibrinogen; Hypertension; Imidazoles; Lipoproteins, LDL; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Tetrazoles	1997
Cardiovascular and renal protective effects of losartan in spontaneously hypertensive rats with diabetes mellitus. Clinical and experimental pharmacology & physiology. Supplement, 1995, Volume: 22, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Diabetes Mellitus, Experimental; Hemodynamics; Hypertension; Imidazoles; Kidney Diseases; Losartan; Male; Nephrectomy; Rats; Rats, Inbred SHR; Tetrazoles	1995
Modulation of renal glomerular angiotensin II receptors by ace inhibition and AT1 receptor antagonism. Regulatory peptides, 1997, Jan-29, Volume: 68, Issue:2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Binding, Competitive; Biphenyl Compounds; Captopril; Heart; Imidazoles; Kidney Glomerulus; Losartan; Male; Membrane Proteins; Organ Size; Peptidyl-Dipeptidase A; Protein Binding; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Tetrazoles	1997
Hypotensive effects of the angiotensin II antagonist telmisartan in conscious chronically-instrumented transgenic rats. Arzneimittel-Forschung, 1996, Volume: 46, Issue:8 Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Blood Pressure; Captopril; Heart Rate; Imidazoles; Losartan; Rats; Telmisartan; Tetrazoles	1996
Nifedipine, losartan and captopril effects on hyperplasia of vascular smooth muscle from Ren-2 transgenic rats. European journal of pharmacology, 1997, Apr-18, Volume: 324, Issue:2-3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Genetically Modified; Antihypertensive Agents; Biphenyl Compounds; Captopril; Hyperplasia; Imidazoles; Losartan; Muscle, Smooth, Vascular; Nifedipine; Rats; Rats, Sprague-Dawley; Tetrazoles	1997
Use of pulsed-wave Doppler echocardiography to measure changes in MPAP. Is further validation required? Chest, 1997, Volume: 111, Issue:5 Topics: Acute Disease; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Captopril; Echocardiography, Doppler, Pulsed; Heart; Humans; Hypertension, Pulmonary; Hypoxia; Imidazoles; Losartan; Lung Diseases, Obstructive; Pulmonary Artery; Pulmonary Heart Disease; Rats; Renin-Angiotensin System; Reproducibility of Results; Tetrazoles; Vasoconstriction	1997
Losartan versus captopril in elderly patients with heart failure. Lancet (London, England), 1997, May-17, Volume: 349, Issue:9063 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Captopril; Heart Failure; Humans; Imidazoles; Losartan; Mortality; Randomized Controlled Trials as Topic; Tetrazoles	1997
Losartan versus captopril in elderly patients with heart failure. Lancet (London, England), 1997, May-17, Volume: 349, Issue:9063 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Captopril; Heart Failure; Humans; Imidazoles; Losartan; Mortality; Tetrazoles	1997
Losartan versus captopril in elderly patients with heart failure. Lancet (London, England), 1997, May-17, Volume: 349, Issue:9063 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Captopril; Heart Failure; Humans; Imidazoles; Kidney; Losartan; Middle Aged; Tetrazoles	1997
Losartan versus captopril in elderly patients with heart failure. Lancet (London, England), 1997, May-17, Volume: 349, Issue:9063 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Captopril; Heart Failure; Humans; Imidazoles; Losartan; Mortality; Randomized Controlled Trials as Topic; Tetrazoles	1997
Endothelial dysfunction in spontaneously hypertensive rats: consequences of chronic treatment with losartan or captopril. Journal of hypertension, 1997, Volume: 15, Issue:6 Topics: Acetylcholine; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Captopril; Endothelium, Vascular; Hypertension; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Superoxide Dismutase; Tetrazoles; Vasoconstriction; Vasodilation	1997
Effects of captopril, losartan, and nifedipine on cell hypertrophy of cultured vascular smooth muscle from hypertensive Ren-2 transgenic rats. British journal of pharmacology, 1997, Volume: 121, Issue:7 Topics: Angiotensin II; Animals; Animals, Genetically Modified; Biphenyl Compounds; Captopril; Cells, Cultured; Hypertension; Hypertrophy; Imidazoles; Losartan; Muscle, Smooth, Vascular; Nifedipine; Protein Biosynthesis; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles	1997
The effect of angiotensin converting enzyme inhibition and angiotensin II receptor antagonism on obstructed rat bladder. The Journal of urology, 1997, Volume: 158, Issue:3 Pt 2 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Captopril; Imidazoles; Losartan; Rats; Rats, Sprague-Dawley; Tetrazoles; Urinary Bladder; Urinary Bladder Neck Obstruction	1997
Role of angiotensin in the dipsogenic effect of bradykinin in rats. Pharmacology, biochemistry, and behavior, 1997, Volume: 57, Issue:4 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Biphenyl Compounds; Bradykinin; Brain; Captopril; Cerebral Ventricles; Drinking; Imidazoles; Immunohistochemistry; Losartan; Male; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles; Thirst	1997
The effect of angiotensin II receptor antagonists on kidney function in two-kidney, two-clip Goldblatt hypertensive rats. European journal of pharmacology, 1997, Jul-23, Volume: 331, Issue:2-3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Benzofurans; Blood Pressure; Captopril; Hypertension, Renovascular; Kidney; Kidney Function Tests; Losartan; Male; Rats; Rats, Wistar	1997
Protective effect of the angiotensin-converting enzyme inhibitor captopril on postischemic myocardial damage in perfused rat heart. Japanese circulation journal, 1997, Volume: 61, Issue:8 Topics: Adenine Nucleotides; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Captopril; Coronary Circulation; Enalapril; Energy Metabolism; Heart Rate; Imidazoles; In Vitro Techniques; Lactic Acid; Losartan; Male; Myocardial Reperfusion Injury; Myocardium; Phosphocreatine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrazoles	1997
Involvement of renin-angiotensin system in hypertensive effect of cadmium in rats. Indian journal of experimental biology, 1997, Volume: 35, Issue:4 Topics: Animals; Antihypertensive Agents; Cadmium; Captopril; Hypertension; Losartan; Male; Rats; Renin; Renin-Angiotensin System; Time Factors	1997
Effects of specific antagonists of angiotensin II receptors and captopril on diabetic nephropathy in mice. Japanese journal of pharmacology, 1997, Volume: 75, Issue:1 Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Creatinine; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Disease Models, Animal; Hypertrophy; Imidazoles; Kidney Diseases; Losartan; Male; Mice; Mice, Inbred Strains; Pyridines; Receptors, Angiotensin; Streptozocin	1997
Effect of captopril, losartan, and bradykinin on early steps of insulin action. Diabetes, 1997, Volume: 46, Issue:12 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Insulin; Insulin Receptor Substrate Proteins; Liver; Losartan; Male; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Receptor, Insulin	1997
Comparative effects of the angiotensin II receptor blocker EXP 3174 and of the angiotensin-converting enzyme inhibitor captopril on renal glomerular hemodynamics in the dog. Kidney & blood pressure research, 1997, Volume: 20, Issue:6 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Blood Pressure; Bradykinin; Captopril; Dogs; Drug Combinations; Female; Glomerular Filtration Rate; Imidazoles; Kidney Glomerulus; Losartan; Male; Potassium; Sodium; Tetrazoles; Urea; Vascular Resistance; Vasodilation; Water	1997
Evaluation of Losartan in the Elderly (ELITE) Trial: clinical implications. European heart journal, 1997, Volume: 18, Issue:8 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Heart Failure; Humans; Losartan; Randomized Controlled Trials as Topic; Treatment Outcome	1997
Blockade of angiotensin II receptors inhibits the increase in blood pressure induced by insulin. Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:2 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine Vasopressin; Blood Glucose; Blood Pressure; Captopril; Ganglionic Blockers; Heart Rate; Hexamethonium; Hormone Antagonists; Infusions, Intravenous; Injections, Intraventricular; Insulin; Losartan; Male; Norepinephrine; Rats; Rats, Wistar; Renin-Angiotensin System; Sympathetic Nervous System; Sympathomimetics	1998
Experimental evidence to support ELITE. Lancet (London, England), 1998, Feb-28, Volume: 351, Issue:9103 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Death, Sudden, Cardiac; Heart; Humans; Losartan	1998
Pulmonary edema induced by angiotensin I in rats. Japanese journal of pharmacology, 1998, Volume: 76, Issue:1 Topics: Adrenergic alpha-Antagonists; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Epinephrine; Losartan; Nitroglycerin; Phentolamine; Pulmonary Edema; Rats; Rats, Wistar; Receptors, Angiotensin; Regression Analysis; Respiration; Vasodilator Agents	1998
The influence of restraint on blood pressure in the rat. Journal of pharmacological and toxicological methods, 1997, Volume: 38, Issue:3 Topics: Animals; Antihypertensive Agents; Blood Pressure; Blood Pressure Determination; Captopril; Heart Rate; Hydralazine; Losartan; Male; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Restraint, Physical; Telemetry	1997
Role of nitric oxide in responses to renin-angiotensin system inhibition in sodium-depleted guinea pig and rat. Clinical and experimental hypertension (New York, N.Y. : 1993), 1998, Volume: 20, Issue:2 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dipeptides; Guinea Pigs; Imidazoles; Losartan; Male; Morpholines; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Rats; Rats, Sprague-Dawley; Renin; Renin-Angiotensin System; Sodium; Tetrazoles	1998
Effects of AT1 receptor blockade on blood pressure and the renin-angiotensin system in spontaneously hypertensive rats of the stroke prone strain. Clinical and experimental hypertension (New York, N.Y. : 1993), 1998, Volume: 20, Issue:2 Topics: Albuminuria; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Captopril; Cerebrovascular Disorders; Gene Expression; Hypertension; Kidney; Losartan; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger; Telmisartan	1998
[Activation of the cardiac angiotensin-converting enzyme after myocardial infarction and its role in ventricular remodeling]. Arquivos brasileiros de cardiologia, 1997, Volume: 69, Issue:2 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Heart; Heart Ventricles; Hemodynamics; Hydroxyproline; Losartan; Male; Myocardial Infarction; Peptidyl-Dipeptidase A; Proteins; Rats; Rats, Inbred Strains; Rats, Wistar; Vasoconstrictor Agents	1997
Renal vascular responses to angiotensin II in conscious spontaneously hypertensive and normotensive rats. Journal of cardiovascular pharmacology, 1998, Volume: 31, Issue:6 Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Kidney Cortex; Losartan; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Regional Blood Flow; Vascular Resistance	1998
The antithrombotic effect of captopril and losartan on experimental arterial thrombosis in rats. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 1998, Volume: 49, Issue:2 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta; Bleeding Time; Blood Platelets; Blood Pressure; Captopril; Losartan; Male; Rats; Rats, Wistar; Thrombosis	1998
Differential action of angiotensin II and activity of angiotensin-converting enzyme in human bypass grafts. The Journal of thoracic and cardiovascular surgery, 1998, Volume: 116, Issue:2 Topics: Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Coronary Artery Bypass; Female; Graft Occlusion, Vascular; Humans; Imidazoles; In Vitro Techniques; Losartan; Male; Middle Aged; Nitric Oxide Synthase; Peptidyl-Dipeptidase A; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Saphenous Vein; Thoracic Arteries; Vasoconstriction; Vasoconstrictor Agents	1998
Effects of losartan and captopril on endothelin-1 production in blood vessels and glomeruli of rats with reduced renal mass. American journal of hypertension, 1998, Volume: 11, Issue:8 Pt 1 Topics: Angiotensin II; Animals; Blood Pressure; Blood Vessels; Captopril; Endothelin-1; Kidney Failure, Chronic; Kidney Glomerulus; Losartan; Male; Nephrectomy; Rats; Rats, Sprague-Dawley	1998
Salt appetite: interaction of forebrain angiotensinergic and hindbrain serotonergic mechanisms. Brain research, 1998, Aug-10, Volume: 801, Issue:1-2 Topics: Angiotensin II; Animals; Appetite; Captopril; Catheterization; Furosemide; Injections, Intraventricular; Injections, Subcutaneous; Losartan; Male; Methysergide; Prosencephalon; Rats; Rats, Sprague-Dawley; Rhombencephalon; Serotonin; Sodium Chloride; Subfornical Organ	1998
The brain is a possible target for an angiotensin-converting enzyme inhibitor in the treatment of chronic heart failure. Journal of cardiac failure, 1998, Volume: 4, Issue:2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Brain; Captopril; Evaluation Studies as Topic; Heart Failure; Hemodynamics; Losartan; Male; Myocardial Infarction; Random Allocation; Rats; Rats, Sprague-Dawley	1998
Insulin-mediated growth in aortic smooth muscle and the vascular renin-angiotensin system. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 32, Issue:3 Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Aorta; Captopril; Cell Division; Cells, Cultured; Insulin; Losartan; Male; Muscle Development; Muscle, Smooth, Vascular; Rats; Rats, Sprague-Dawley; Receptor, IGF Type 1; Renin-Angiotensin System; Serine Proteinase Inhibitors; Thymidine; Vasoconstrictor Agents	1998
Angiotensin II receptor antagonists for heart failure. Heart (British Cardiac Society), 1998, Volume: 80, Issue:1 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bradykinin; Captopril; Clinical Trials as Topic; Heart Failure; Humans; Losartan; Receptors, Angiotensin	1998
Evidence that brain angiotensin II is involved in both thirst and sodium appetite in baboons. The American journal of physiology, 1998, Volume: 275, Issue:5 Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Appetite; Brain; Captopril; Drinking; Injections, Intraventricular; Losartan; Male; Naphthyridines; Papio; Receptors, Angiotensin; Sodium, Dietary	1998
A case of renal artery stenosis after transplantation: can losartan be more accurate than captopril renography? Clinical nuclear medicine, 1998, Volume: 23, Issue:11 Topics: Adult; Antihypertensive Agents; Captopril; Humans; Hypertension, Renovascular; Kidney Transplantation; Losartan; Male; Postoperative Complications; Radioisotope Renography; Radiopharmaceuticals; Renal Artery Obstruction; Technetium Tc 99m Pentetate; Time Factors	1998
Hypertrophic response to hemodynamic overload: role of load vs. renin-angiotensin system activation. The American journal of physiology, 1999, Volume: 276, Issue:2 Pt 2 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cats; Constriction, Pathologic; Elasticity; Heart; Hemodynamics; Hypertension; Hypertrophy, Right Ventricular; Losartan; Myocardial Contraction; Myocardium; Pulmonary Artery; Renin-Angiotensin System	1999
Inhibition of beta-myosin heavy chain gene expression in pressure overload rat heart by losartan and captopril. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1997, Volume: 18, Issue:1 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Coarctation; Captopril; Gene Expression Regulation; Hypertrophy, Left Ventricular; Losartan; Male; Myosin Heavy Chains; Rats; Rats, Wistar; RNA, Messenger	1997
Comparison of the effects of losartan and captopril on mortality in patients after acute myocardial infarction: the OPTIMAAL trial design. Optimal Therapy in Myocardial Infarction with the Angiotensin II Antagonist Losartan. The American journal of cardiology, 1999, Feb-15, Volume: 83, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Double-Blind Method; Humans; Losartan; Multicenter Studies as Topic; Myocardial Infarction; Randomized Controlled Trials as Topic; Research Design; Survival Analysis; Treatment Outcome	1999
Bradykinin and inhibition of angiotensin-converting enzyme in hypertension. The New England journal of medicine, 1999, Mar-25, Volume: 340, Issue:12 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Drug Therapy, Combination; Humans; Hypertension; Losartan; Renin-Angiotensin System	1999
Analysis of responses to angiotensin I (3-10) and Leu3 angiotensin (3-8) in the pulmonary vascular bed of the cat. American journal of therapeutics, 1998, Volume: 5, Issue:5 Topics: Angiotensin I; Angiotensin II; Animals; Blood Pressure; Captopril; Cats; Dose-Response Relationship, Drug; Female; Imidazoles; Losartan; Male; Peptide Fragments; Pulmonary Artery; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin	1998
Angiotensin II attenuates renal cortical cyclooxygenase-2 expression. The Journal of clinical investigation, 1999, Volume: 103, Issue:7 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Gene Expression Regulation, Enzymologic; Isoenzymes; Kidney Cortex; Losartan; Male; Mice; Mice, Knockout; Phorbol Esters; Prostaglandin-Endoperoxide Synthases; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin; Renin-Angiotensin System; RNA, Messenger	1999
Local renin-angiotensin system is involved in K+-induced aldosterone secretion from human adrenocortical NCI-H295 cells. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:4 Topics: Adrenal Cortex; Aldosterone; Angiotensinogen; Captopril; Cells, Cultured; Humans; Losartan; Peptidyl-Dipeptidase A; Potassium; Renin; Renin-Angiotensin System	1999
Effect of losartan and captopril on expression of cardiac angiotensin II AT1 receptor mRNA in rats following myocardial infarction. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1997, Volume: 18, Issue:5 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Gene Expression Regulation; Losartan; Male; Myocardial Infarction; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; RNA, Messenger	1997
AT1-receptor antagonists for the treatment of chronic heart failure. Cardiovascular research, 1999, Volume: 41, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Captopril; Dogs; Heart Failure; Humans; Irbesartan; Losartan; Rats; Tetrazoles	1999
Functional evidence for subfornical organ-intrinsic conversion of angiotensin I to angiotensin II. The American journal of physiology, 1999, Volume: 276, Issue:6 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dose-Response Relationship, Drug; Drinking; Electrophysiology; Losartan; Male; Rats; Rats, Wistar; Reaction Time; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Subfornical Organ	1999
The effect of losartan and captopril on glomerular basement membrane anionic charge in a diabetic rat model. Journal of hypertension, 1999, Volume: 17, Issue:8 Topics: Albuminuria; Angiotensin Receptor Antagonists; Animals; Anions; Antihypertensive Agents; Captopril; Cell Membrane; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Glomerular Mesangium; Glycosaminoglycans; Losartan; Rats; Rats, Wistar; Sialic Acids; Streptozocin	1999
EXP3174, the AII antagonist human metabolite of losartan, but not losartan nor the angiotensin-converting enzyme inhibitor captopril, prevents the development of lethal ischemic ventricular arrhythmias in a canine model of recent myocardial infarction. Journal of the American College of Cardiology, 1999, Volume: 34, Issue:3 Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Captopril; Disease Models, Animal; Dogs; Drug Evaluation, Preclinical; Female; Heart Ventricles; Humans; Imidazoles; Losartan; Male; Myocardial Infarction; Myocardial Ischemia; Tetrazoles; Time Factors	1999
Angiotensin regulates the selectivity of the Na+-K+ pump for intracellular Na+. The American journal of physiology, 1999, Volume: 277, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Captopril; Electrophysiology; Enzyme Activation; Extracellular Space; Heart Ventricles; Intracellular Membranes; Losartan; Male; Myocardium; Potassium; Protein Kinase C; Rabbits; Sodium; Sodium-Potassium-Exchanging ATPase	1999
Ventricular remodeling and transforming growth factor-beta 1 mRNA expression after nontransmural myocardial infarction in rats: effects of angiotensin converting enzyme inhibition and angiotensin II type 1 receptor blockade. Basic research in cardiology, 1999, Volume: 94, Issue:4 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Echocardiography; Female; Hemodynamics; Losartan; Myocardial Infarction; Rats; Rats, Sprague-Dawley; RNA, Messenger; Transforming Growth Factor beta; Ventricular Function, Left	1999
Angiotensin II receptor antagonists prevent neointimal proliferation in a porcine coronary artery organ culture model. Cardiovascular research, 1999, Volume: 42, Issue:3 Topics: Analysis of Variance; Angioplasty, Balloon, Coronary; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Cell Division; Coronary Disease; Coronary Vessels; Culture Techniques; Imidazoles; Losartan; Muscle, Smooth, Vascular; Pyridines; Recurrence; Swine; Tetrazoles	1999
Dynamic Ca2+ signalling in rat arterial smooth muscle cells under the control of local renin-angiotensin system. The Journal of physiology, 1999, Dec-01, Volume: 521 Pt 2 Topics: 1-Sarcosine-8-Isoleucine Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Aniline Compounds; Animals; Antihypertensive Agents; Arteries; Calcium; Calcium Signaling; Calcium-Transporting ATPases; Captopril; Enzyme Inhibitors; Estrenes; Evoked Potentials; Fluorescent Dyes; Indoles; Losartan; Male; Muscle, Smooth, Vascular; Periodicity; Phosphodiesterase Inhibitors; Pyrrolidinones; Rats; Rats, Wistar; Renin-Angiotensin System; Sarcoplasmic Reticulum; Stimulation, Chemical; Tail; Type C Phospholipases; Vasoconstriction; Xanthenes	1999
Renal vascular reactivity in mice: AngII-induced vasoconstriction in AT1A receptor null mice. Journal of the American Society of Nephrology : JASN, 1999, Volume: 10, Issue:12 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Female; Imidazoles; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Oligopeptides; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renal Circulation; Renin; Vasoconstriction	1999
The human renin infused rat: use as an in vivo model for the biological evaluation of human renin inhibitors. Canadian journal of physiology and pharmacology, 1999, Volume: 77, Issue:11 Topics: Administration, Oral; Angiotensin I; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dipeptides; Dose-Response Relationship, Drug; Drug Evaluation, Preclinical; Ganglionic Blockers; Humans; In Vitro Techniques; Losartan; Male; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Renin; Time Factors	1999
Timed inhibition of the renin-angiotensin system suppresses the rise in blood pressure upon awakening in spontaneously hypertensive rats. American journal of hypertension, 1999, Volume: 12, Issue:11 Pt 1 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Chronotherapy; Enalaprilat; Hypertension; Infusions, Intravenous; Losartan; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System	1999
Changes in angiotensin converting enzyme activity in the renal vascular bed of streptozotocin-induced diabetic rat. Research communications in molecular pathology and pharmacology, 1999, Volume: 104, Issue:2 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Glucose; Captopril; Diabetes Mellitus, Experimental; Drug Interactions; Kidney; Losartan; Male; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Wistar; Renal Artery; Streptozocin; Vasoconstriction	1999
High- or low-salt diet from weaning to adulthood: effect on insulin sensitivity in Wistar rats. Hypertension (Dallas, Tex. : 1979), 2000, Volume: 35, Issue:1 Pt 2 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biological Transport; Body Weight; Captopril; Diet, Sodium-Restricted; Glucose; Glucose Transporter Type 4; Hyperinsulinism; Insulin Resistance; Losartan; Male; Monosaccharide Transport Proteins; Muscle Proteins; Rats; Rats, Wistar; Sodium Chloride, Dietary; Weaning	2000
Angiotensin-converting enzyme inhibitors downregulate tissue factor synthesis in monocytes. Circulation research, 2000, Feb-04, Volume: 86, Issue:2 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Antihypertensive Agents; Blood Coagulation; Captopril; Cell Nucleus; Dimerization; Endotoxins; Gene Expression; Humans; In Vitro Techniques; Losartan; Monocytes; NF-kappa B; Proto-Oncogene Proteins c-rel; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; RNA, Messenger; Thromboplastin	2000
ELITE II. AT1-blockers not better, but more tolerable than ACE-inhibitors. Der Internist, 2000, Volume: 41, Issue:1 Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Female; Heart Failure; Humans; Losartan; Male; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome	2000
Comparative effects of pretreatment with captopril and losartan on cardiovascular protection in a rat model of ischemia-reperfusion. Journal of the American College of Cardiology, 2000, Mar-01, Volume: 35, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Captopril; Disease Models, Animal; Electrocardiography; Female; Heart Rate; Losartan; Myocardial Infarction; Myocardial Reperfusion Injury; Random Allocation; Rats; Rats, Sprague-Dawley; Renin; Treatment Outcome; Ventricular Fibrillation	2000
The role of endothelin, protein kinase C and free radicals in the mechanism of the post-ischemic endothelial dysfunction in guinea-pig hearts. Journal of molecular and cellular cardiology, 2000, Volume: 32, Issue:2 Topics: Acetylcholine; Adrenergic alpha-Antagonists; Alkaloids; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Aspartic Acid Endopeptidases; Benzophenanthridines; Bosentan; Captopril; Catalase; Coronary Vessels; Endothelin-Converting Enzymes; Endothelins; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Female; Free Radicals; Glycopeptides; Guinea Pigs; Heart; Losartan; Male; Metalloendopeptidases; Muscle Proteins; Myocardial Ischemia; Myocardial Reperfusion; Myocardium; Nitroprusside; Oxidative Stress; Phenanthridines; Prazosin; Protein Kinase C; Reactive Oxygen Species; Sulfonamides; Superoxide Dismutase; Tetradecanoylphorbol Acetate; Vasodilator Agents	2000
Angiotensin II mediates pressure loading-induced mitogen-activated protein kinase activation in isolated rat aorta. European journal of pharmacology, 2000, Mar-17, Volume: 391, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Calcium; Calcium Channel Blockers; Captopril; Enzyme Activation; In Vitro Techniques; Ion Channel Gating; Losartan; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Nifedipine; Pepstatins; Rats; Rats, Wistar; Renin; Stress, Mechanical	2000
Update of ELITE-II, BEST, CHAMP, and IMPRESS clinical trials in heart failure. European journal of heart failure, 2000, Volume: 2, Issue:1 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Exercise Tolerance; Heart Failure; Humans; Losartan; Pyridines; Randomized Controlled Trials as Topic; Thiazepines	2000
Activation of renal afferent pathways following furosemide treatment. II. Effect Of angiotensin blockade. Brain research, 2000, Apr-10, Volume: 861, Issue:2 Topics: Afferent Pathways; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain Stem; Captopril; Diuretics; Furosemide; Hypothalamus; Hypovolemia; Kidney; Losartan; Male; Posterior Horn Cells; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Subfornical Organ	2000
All that glitters is not gold. Lancet (London, England), 2000, May-06, Volume: 355, Issue:9215 Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Captopril; Heart Failure; Humans; Losartan; Randomized Controlled Trials as Topic; Ventricular Dysfunction, Left	2000
Role of adrenal renin-angiotensin system in the control of aldosterone secretion in sodium-restricted rats. American journal of physiology. Endocrinology and metabolism, 2000, Volume: 278, Issue:6 Topics: Adrenal Glands; Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diet, Sodium-Restricted; Losartan; Male; Potassium; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Saralasin	2000
[Angiotensin II antagonists: a promising pathway]. Archives des maladies du coeur et des vaisseaux, 2000, Volume: Spec No Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cardiac Output, Low; Chymases; Humans; Losartan; Renin-Angiotensin System; Serine Endopeptidases; Vasodilator Agents	2000
Comparison of losartan and captopril in ELITE II. Lancet (London, England), 2000, Sep-02, Volume: 356, Issue:9232 Topics: Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Captopril; Heart Failure; Humans; Losartan	2000
Comparison of losartan and captopril in ELITE II. Lancet (London, England), 2000, Sep-02, Volume: 356, Issue:9232 Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Captopril; Heart Failure; Humans; Losartan	2000
Comparison of losartan and captopril in ELITE II. Lancet (London, England), 2000, Sep-02, Volume: 356, Issue:9232 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Anti-Arrhythmia Agents; Captopril; Dose-Response Relationship, Drug; Drug Administration Schedule; Heart Failure; Humans; Losartan	2000
Comparison of losartan and captopril in ELITE II. Lancet (London, England), 2000, Sep-02, Volume: 356, Issue:9232 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Drug Administration Schedule; Heart Failure; Humans; Losartan; Middle Aged	2000
Role of cardiac renin-angiotensin system in sarcoplasmic reticulum function and gene expression in the ischemic-reperfused heart. Molecular and cellular biochemistry, 2000, Volume: 212, Issue:1-2 Topics: Animals; Calcium; Calcium-Binding Proteins; Calcium-Transporting ATPases; Calsequestrin; Captopril; Gene Expression Regulation; Heart; In Vitro Techniques; Losartan; Male; Myocardial Reperfusion; Myocardium; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Ryanodine Receptor Calcium Release Channel; Sarcoplasmic Reticulum; Sarcoplasmic Reticulum Calcium-Transporting ATPases	2000
Mitogen-activated protein kinase activity regulation role of angiotensin and endothelin systems in vascular smooth muscle cells. European journal of pharmacology, 2001, Jan-05, Volume: 411, Issue:1-2 Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cells, Cultured; Dose-Response Relationship, Drug; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Glycopeptides; Losartan; Male; Mitogen-Activated Protein Kinases; Muscle, Smooth, Vascular; Pepstatins; Peptides, Cyclic; Protease Inhibitors; Protein Precursors; Rats; Rats, Wistar; Renin	2001
[Current role of angiotensin II antagonists in the treatment of heart failure]. Italian heart journal. Supplement : official journal of the Italian Federation of Cardiology, 2000, Volume: 1, Issue:9 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Chronic Disease; Clinical Trials as Topic; Drug Evaluation; Heart Failure; Humans; Losartan	2000
Interaction between paracrine tumor necrosis factor-alpha and paracrine angiotensin II during myocardial ischemia. Journal of the American College of Cardiology, 2001, Volume: 37, Issue:1 Topics: Angiotensin II; Animals; Animals, Newborn; Captopril; Cells, Cultured; Losartan; Male; Myocardial Reperfusion Injury; Paracrine Communication; Rats; Rats, Wistar; Tumor Necrosis Factor-alpha	2001
Chronic losartan treatment decreases angiotensin II-mediated facilitation of noradrenaline release in the caudal artery of spontaneously hypertensive rats. Life sciences, 2000, Nov-17, Volume: 67, Issue:26 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arteries; Blood Pressure; Captopril; Hypertrophy, Left Ventricular; Losartan; Male; Norepinephrine; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Sympathetic Nervous System; Synapses; Vasoconstriction	2000
Are angiotensin II receptor blockers more efficacious than placebo in heart failure? Implications of ELITE-2. Evaluation of Losartan In The Elderly. The American journal of cardiology, 2001, Mar-01, Volume: 87, Issue:5 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cause of Death; Chronic Disease; Heart Failure; Humans; Losartan; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Angiotensin; Survival Rate; Treatment Outcome	2001
AT1 receptor antagonism enhances angiotensin-II-facilitated carrageenan-induced paw edema. Methods and findings in experimental and clinical pharmacology, 2000, Volume: 22, Issue:8 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carrageenan; Disease Models, Animal; Drug Synergism; Edema; Extremities; Inflammation; Losartan; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Vasoconstrictor Agents	2000
Inhibition of angiotensin II-induced facilitation of sympathetic neurotransmission in the pithed rat: a comparison between losartan, irbesartan, telmisartan, and captopril. Journal of hypertension, 2001, Volume: 19, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Benzoates; Biphenyl Compounds; Captopril; Decerebrate State; Electric Stimulation; Irbesartan; Losartan; Male; Norepinephrine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System; Synaptic Transmission; Telmisartan; Tetrazoles	2001
Effects of angiotensin-converting enzyme and angiotensin II on hypoxia-induced proliferation of cultured intra-pulmonary artery smooth muscle cells. Acta pharmacologica Sinica, 2000, Volume: 21, Issue:4 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Division; Cell Hypoxia; Cells, Cultured; Imidazoles; Losartan; Muscle, Smooth, Vascular; Pulmonary Artery; Pyridines; Rabbits	2000
Suppression of experimental abdominal aortic aneurysms in the rat by treatment with angiotensin-converting enzyme inhibitors. Journal of vascular surgery, 2001, Volume: 33, Issue:5 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Abdominal; Aortic Aneurysm, Abdominal; Blood Pressure; Captopril; Enalapril; Lisinopril; Losartan; Male; Pancreatic Elastase; Rats; Rats, Wistar	2001
[Evaluation of the evenness of the antihypertensive effect of losartan and captopril by using a 24-hour monitoring of arterial pressure]. Terapevticheskii arkhiv, 2001, Volume: 73, Issue:2 Topics: Age Factors; Aged; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Captopril; Humans; Hypertension; Losartan; Male; Middle Aged; Sex Factors; Time Factors	2001
Comparative studies on the memory-enhancing actions of captopril and losartan in mice using inhibitory shock avoidance paradigm. Neuropeptides, 2001, Volume: 35, Issue:1 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Avoidance Learning; Captopril; Dizocilpine Maleate; Electroshock; Enzyme Inhibitors; Losartan; Male; Memory; Mice; Mice, Inbred Strains; Muscarinic Antagonists; Neuroprotective Agents; NG-Nitroarginine Methyl Ester; Reaction Time; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Scopolamine	2001
Differential effect of chronic antihypertensive treatment on vascular smooth muscle cell phenotype in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:5 Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cell Cycle; Cell Division; Cells, Cultured; Endothelium, Vascular; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Muscle, Smooth, Vascular; Phenotype; Rats; Rats, Inbred SHR; Structure-Activity Relationship; Vasoconstriction	2001
Relative efficacy of an angiotensin II antagonist compared with other antihypertensive agents. Olmesartan medoxomil versus antihypertensives. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 2001, Volume: 19, Issue:1 Topics: Angiotensin II; Antihypertensive Agents; Atenolol; Captopril; Clinical Trials, Phase III as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Hypertension; Imidazoles; Losartan; Multicenter Studies as Topic; Olmesartan Medoxomil; Randomized Controlled Trials as Topic; Tetrazoles	2001
Anaemia due to ACE inhibitors and losartan in patients with renal failure. Prescrire international, 1999, Volume: 8, Issue:44 Topics: Anemia; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Humans; Hypertension; Kidney Failure, Chronic; Losartan; Renal Dialysis; Treatment Outcome	1999
Comparative effects of ACE inhibitors and an angiotensin receptor blocker on atherosclerosis and vascular function. Journal of cardiovascular pharmacology and therapeutics, 2001, Volume: 6, Issue:2 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arteriosclerosis; Captopril; Cholesterol; Disease Models, Animal; Isoquinolines; Kinins; Losartan; Male; Nitric Oxide; Quinapril; Rabbits; Receptors, Angiotensin; Tetrahydroisoquinolines; Vasoconstriction; Vasodilation	2001
Angiotensin II and VEGF are involved in angiogenesis induced by short-term exercise training. American journal of physiology. Heart and circulatory physiology, 2001, Volume: 281, Issue:3 Topics: Angiotensin II; Animals; Antibodies; Antihypertensive Agents; Blood Pressure; Blotting, Western; Body Composition; Body Weight; Captopril; Cell Count; Densitometry; Endothelial Growth Factors; Losartan; Lymphokines; Male; Microcirculation; Muscle, Skeletal; Neovascularization, Physiologic; Physical Conditioning, Animal; Rats; Rats, Sprague-Dawley; Vascular Endothelial Growth Factor A; Vascular Endothelial Growth Factors	2001
Renal vascular effects of frusemide in the rat: influence of salt loading and the role of angiotensin II. Experimental physiology, 2001, Volume: 86, Issue:5 Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biological Transport; Captopril; Diuretics; Furosemide; Kidney; Kidney Tubules; Laser-Doppler Flowmetry; Losartan; Male; Rats; Rats, Wistar; Renal Circulation; Sodium; Sodium Chloride; Time Factors; Urination; Vasoconstriction	2001
Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia. The Journal of endocrinology, 2001, Volume: 171, Issue:1 Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Norepinephrine; Oligopeptides; Prostate; Prostatic Hyperplasia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sympathetic Nervous System; Synaptic Transmission	2001
[In contrast to captopril and enalapril, losartan does not increase mortality of gerbils after carotid ligation]. Archives des maladies du coeur et des vaisseaux, 2001, Volume: 94, Issue:8 Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cardiovascular Surgical Procedures; Carotid Arteries; Disease Models, Animal; Enalapril; Gerbillinae; Ligation; Losartan; Myocardial Ischemia; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Survival Analysis	2001
Interaction between sodium intake, angiotensin II, and blood pressure as a cause of cardiac hypertrophy. American journal of hypertension, 2001, Volume: 14, Issue:9 Pt 1 Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cardiomegaly; Circadian Rhythm; Cross-Over Studies; Disease Models, Animal; France; Heart; Hypertension, Renovascular; Kidney; Losartan; Models, Cardiovascular; Organ Size; Rats; Rats, Wistar; Renin; Sodium, Dietary; Telemetry	2001
Angiotensin II type 1 receptor blockers and congestive heart failure. Circulation, 2001, Oct-09, Volume: 104, Issue:15 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Heart Failure; Humans; Losartan; Receptor, Angiotensin, Type 1; Sample Size; Selection Bias; Tetrazoles; Treatment Outcome; Valine; Valsartan	2001
Angiotensins II and IV stimulate the rat adrenocortical cell proliferation acting via different receptors. Endocrine regulations, 2001, Volume: 35, Issue:3 Topics: Adrenal Cortex; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Division; Losartan; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptors, Angiotensin	2001
Corpuscles of Stannius secrete renin or an isorenin that regulates cardiovascular function in freshwater North American eels, Anguilla rostrata LeSueur. General and comparative endocrinology, 2001, Volume: 124, Issue:2 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Anguilla; Animals; Anti-Arrhythmia Agents; Blood Flow Velocity; Captopril; Endocrine Glands; Female; Imidazoles; Losartan; Pepstatins; Protease Inhibitors; Pyridines; Renin; Renin-Angiotensin System; Ultrasonography, Doppler	2001
Comparative effects of losartan and captopril on ventricular remodeling and function after myocardial infarction in the rat. Chinese medical sciences journal = Chung-kuo i hsueh k'o hsueh tsa chih, 1998, Volume: 13, Issue:1 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Heart Function Tests; Losartan; Male; Myocardial Infarction; Random Allocation; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Ultrasonography; Ventricular Remodeling	1998
Are angiotensin II receptor blockers indicated in chronic heart failure? Heart (British Cardiac Society), 2002, Volume: 87, Issue:1 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chronic Disease; Heart Failure; Humans; Losartan; Randomized Controlled Trials as Topic; Tetrazoles; Valine; Valsartan	2002
Effect of combining an ACE inhibitor and an angiotensin II receptor blocker on plasma and kidney tissue angiotensin II levels. American journal of kidney diseases : the official journal of the National Kidney Foundation, 2002, Volume: 39, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Kidney; Losartan; Male; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sodium, Dietary	2002
Effects of high glucose on interleukin-6 production in human mesangial cells. Journal of Korean medical science, 2002, Volume: 17, Issue:2 Topics: Angiotensin II; Captopril; Cells, Cultured; Gene Expression; Glomerular Mesangium; Glucose; Humans; Interleukin-6; Losartan	2002
Interaction of ACE inhibitors and AT(1)-receptor blockers on maximum blood pressure response in spontaneous hypertensive rats. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2002, Volume: 3, Issue:1 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Drug Interactions; Drug Therapy, Combination; Hypertension; Losartan; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Telemetry	2002
Angiotensin II supports sympathetically mediated vasopressor response to footshock-stress. Journal of human hypertension, 2002, Volume: 16 Suppl 1 Topics: Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cardiovascular Physiological Phenomena; Catecholamines; Electroshock; Heart Rate; Losartan; Male; Nephrectomy; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Sympathetic Nervous System	2002
Effects of captopril and losartan on myocardial ischemia-reperfusion induced arrhythmias and necrosis in rats. Pharmacological research, 2002, Volume: 45, Issue:4 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Pressure; Captopril; Heart Rate; Hemodynamics; Losartan; Male; Myocardial Reperfusion Injury; Myocardium; Necrosis; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1	2002
The renin-angiotensin-aldosterone system excites hypothalamic paraventricular nucleus neurons in heart failure. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 283, Issue:1 Topics: Action Potentials; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Denervation; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography; Heart Failure; Injections, Intra-Arterial; Injections, Intravenous; Losartan; Male; Mineralocorticoid Receptor Antagonists; Myocardial Ischemia; Neurons; Paraventricular Hypothalamic Nucleus; Pressoreceptors; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Spironolactone	2002
Role of endothelin receptors in the hypertensive state of kinin B(2) knockout mice subjected to a high-salt diet. Clinical science (London, England : 1979), 2002, Volume: 103 Suppl 48 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Endothelin Receptor Antagonists; Endothelin-1; Endothelins; Female; Hypertension; Kidney; Losartan; Male; Mice; Mice, Knockout; Myocardium; Oligopeptides; Peptides, Cyclic; Piperidines; Protein Precursors; Receptor, Bradykinin B2; Receptor, Endothelin A; Receptor, Endothelin B; Receptors, Angiotensin; Receptors, Bradykinin; Receptors, Endothelin; RNA, Messenger; Sodium Chloride, Dietary	2002
Effect of angiotensin II on ion transport across human Fallopian tube epithelial cells in vitro. Reproduction (Cambridge, England), 2002, Volume: 124, Issue:4 Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biological Transport; Captopril; Cell Culture Techniques; Electrophysiology; Epithelial Cells; Fallopian Tubes; Female; Humans; Ion Transport; Losartan; Middle Aged; Receptor, Angiotensin, Type 1	2002
Antithrombotic effect of captopril and losartan is mediated by angiotensin-(1-7). Hypertension (Dallas, Tex. : 1979), 2002, Volume: 40, Issue:5 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Disease Models, Animal; Dose-Response Relationship, Drug; Drug Synergism; Enzyme Inhibitors; Epoprostenol; Fibrinolytic Agents; Hypertension, Renal; Imidazoles; Infusions, Intravenous; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Tetrazoles; Venous Thrombosis	2002
Low doses of angiotensin converting enzyme inhibitors and angiotensin type 1 blockers have a synergistic effect but high doses are less than additive. American journal of hypertension, 2002, Volume: 15, Issue:11 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Disease Models, Animal; Drug Synergism; Drug Therapy, Combination; Hypertension; Losartan; Rats; Rats, Inbred SHR	2002
The OPTIMAAL trial: losartan or captopril after acute myocardial infarction. Lancet (London, England), 2002, Dec-07, Volume: 360, Issue:9348 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Humans; Losartan; Myocardial Infarction; Time Factors	2002
The OPTIMMAL trial: losartan or captopril after acute myocardial infarction. Lancet (London, England), 2002, Dec-07, Volume: 360, Issue:9348 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Humans; Losartan; Myocardial Infarction	2002
The OPTIMMAL trial: losartan or captopril after acute myocardial infarction. Lancet (London, England), 2002, Dec-07, Volume: 360, Issue:9348 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Humans; Losartan; Myocardial Infarction	2002
The OPTIMMAL trial: losartan or captopril after acute myocardial infarction. Lancet (London, England), 2002, Dec-07, Volume: 360, Issue:9348 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Humans; Losartan; Myocardial Infarction	2002
The OPTIMMAL trial: losartan or captopril after acute myocardial infarction. Lancet (London, England), 2002, Dec-07, Volume: 360, Issue:9348 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Clinical Trials as Topic; Humans; Losartan; Myocardial Infarction	2002
[Is it real to replace angiotensin converting enzyme inhibitors as basic remedy in the treatment of chronic heart failure?]. Kardiologiia, 2002, Volume: 42, Issue:12 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Chronic Disease; Clinical Trials as Topic; Dose-Response Relationship, Drug; Heart Failure; Humans; Losartan	2002
Collagenofibrotic glomerulopathy with a widespread expression of type-V collagen. Virchows Archiv : an international journal of pathology, 2003, Volume: 442, Issue:2 Topics: Aged; Captopril; Collagen Type III; Collagen Type V; Female; Fluorescent Antibody Technique, Indirect; Humans; Immunoenzyme Techniques; Kidney Diseases; Kidney Glomerulus; Losartan; Microscopy, Immunoelectron	2003
[Suboptimal results of Optimaal: treatment with ACE inhibitors remains the preferred therapy in patients with left ventricular dysfunction after acute myocardial infarct]]. Herz, 2002, Volume: 27, Issue:8 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Cause of Death; Female; Humans; Length of Stay; Losartan; Male; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic; Stroke; Survival Rate; Treatment Outcome; Ventricular Dysfunction, Left	2002
Effect of ANG II type I receptor antagonist and ACE inhibitor on vitamin D receptor-null mice. American journal of physiology. Regulatory, integrative and comparative physiology, 2003, Volume: 285, Issue:1 Topics: Aldosterone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Female; Gene Expression; Kidney; Losartan; Male; Mice; Mice, Mutant Strains; Receptor, Angiotensin, Type 1; Receptors, Calcitriol; Renin; Salts; Submandibular Gland; Water; Water-Electrolyte Balance	2003
Comparative effects of aspirin with ACE inhibitor or angiotensin receptor blocker on myocardial infarction and vascular function. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2003, Volume: 4, Issue:1 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Captopril; Disease Models, Animal; Endothelium, Vascular; Female; Hemodynamics; Losartan; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Vasodilation; Ventricular Fibrillation	2003
Vasoactive effects of erythropoietin on human placental blood vessels in vitro. American journal of obstetrics and gynecology, 2003, Volume: 188, Issue:4 Topics: Adult; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Arteries; Captopril; Dose-Response Relationship, Drug; Erythropoietin; Female; Humans; In Vitro Techniques; Losartan; Placental Circulation; Pregnancy; Receptor, Angiotensin, Type 1; Recombinant Proteins; Vasoconstriction; Vasoconstrictor Agents; Veins	2003
Inhibition of amiodarone-induced lung fibrosis but not alveolitis by angiotensin system antagonists. Pharmacology & toxicology, 2003, Volume: 92, Issue:2 Topics: Amiodarone; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Apoptosis; Captopril; Epithelium; Losartan; Lung; Male; Pulmonary Alveoli; Pulmonary Fibrosis; Rats; Rats, Wistar; Time Factors	2003
What did we learn from the OPTIMAAL trial? What can we expect from VALIANT? American heart journal, 2003, Volume: 145, Issue:5 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cause of Death; Heart Failure; Humans; Losartan; Myocardial Infarction; Randomized Controlled Trials as Topic	2003
Myogenic constriction is increased in mesenteric resistance arteries from rats with chronic heart failure: instantaneous counteraction by acute AT1 receptor blockade. British journal of pharmacology, 2003, Volume: 139, Issue:7 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bridged Bicyclo Compounds, Heterocyclic; Captopril; Chronic Disease; Coronary Vessels; Disease Models, Animal; Endothelium-Dependent Relaxing Factors; Endothelium, Vascular; Fatty Acids, Unsaturated; Heart; Heart Failure; Hydrazines; Imidazoles; Indomethacin; Lisinopril; Losartan; Male; Mesenteric Arteries; Nitric Oxide; omega-N-Methylarginine; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Superoxide Dismutase; Sympathetic Nervous System; Tetrazoles; Tetrodotoxin; Vascular Resistance	2003
Effects of captopril and losartan on lipid peroxidation, protein oxidation and nitric oxide release in diabetic rat kidney. Prostaglandins, leukotrienes, and essential fatty acids, 2003, Volume: 69, Issue:4 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Diabetes Mellitus, Experimental; Diabetic Nephropathies; Female; Kidney; Lipid Peroxidation; Losartan; Nitric Oxide; Oxidation-Reduction; Oxidative Stress; Proteins; Rats; Rats, Wistar	2003
The OPTIMAAL study, not so optimal: the lessons of LIFE, RENAAL and IDNT. The Canadian journal of cardiology, 2003, Volume: 19, Issue:9 Topics: Adult; Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Dose-Response Relationship, Drug; Drug Administration Schedule; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic; Survival Analysis; Treatment Outcome; Ventricular Dysfunction, Left	2003
Congestive heart failure: guidelines for the primary care physician. The Mount Sinai journal of medicine, New York, 2003, Volume: 70, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Diagnosis, Differential; Diuretics; Heart Failure; Humans; Losartan; Primary Health Care; Risk Factors	2003
Angiotensin-converting enzyme inhibitors: optimal management of cardiovascular risk. The American journal of cardiology, 2003, Oct-01, Volume: 92, Issue:7 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Cardiovascular Diseases; Diabetic Nephropathies; Evidence-Based Medicine; Humans; Hypertension; Losartan; Risk Management; Treatment Outcome	2003
Polymeric IgA1 from patients with IgA nephropathy upregulates transforming growth factor-beta synthesis and signal transduction in human mesangial cells via the renin-angiotensin system. Journal of the American Society of Nephrology : JASN, 2003, Volume: 14, Issue:12 Topics: Captopril; Cells, Cultured; Genes, ras; Glomerular Mesangium; Glomerulonephritis, IGA; Humans; Immunoglobulin A; Losartan; Renin; Renin-Angiotensin System; RNA, Messenger; Signal Transduction; Transforming Growth Factor beta; Up-Regulation	2003
Temporary losartan or captopril in young SHR induces malignant hypertension despite initial normotension. Kidney international, 2004, Volume: 65, Issue:2 Topics: Animals; Animals, Suckling; Antihypertensive Agents; Blood Pressure; Captopril; Female; Hypertension, Renal; Losartan; Muscle, Smooth, Vascular; Pregnancy; Prenatal Exposure Delayed Effects; Radial Artery; Rats; Rats, Inbred SHR; Renal Artery	2004
[New options against undertreatment]. MMW Fortschritte der Medizin, 2003, Dec-04, Volume: 145, Issue:49 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Clinical Trials as Topic; Heart Failure; Hospitalization; Humans; Losartan; Myocardial Infarction; Risk Factors; Stroke Volume; Tetrazoles; Time Factors; Valine; Valsartan	2003
Role of angiotensin II in ischemia/reperfusion-induced leukocyte-endothelium interactions in the colon. FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2004, Volume: 18, Issue:7 Topics: Allopurinol; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Capillaries; Captopril; Cell Adhesion; Chemokines; Chemotaxis, Leukocyte; Colon; Constriction; Disease Models, Animal; Endothelium, Vascular; Enzyme Induction; Gene Expression Regulation; Inflammation; Ischemia; Leukocyte Count; Leukocytes; Losartan; Male; Mesenteric Artery, Superior; Mice; Mice, Inbred C57BL; Mice, Knockout; P-Selectin; Reactive Oxygen Species; Reperfusion Injury; Superoxide Dismutase	2004
Tonic angiotensinergic inputs to neurons in the anterior hypothalamic area of rats. Brain research, 2004, May-01, Volume: 1006, Issue:2 Topics: Acetylcholine; Action Potentials; Adrenergic alpha-Agonists; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Anterior Hypothalamic Nucleus; Anti-Arrhythmia Agents; Captopril; Dose-Response Relationship, Drug; Drug Interactions; Glutamic Acid; Imidazoles; Losartan; Male; Muscarinic Antagonists; Neurons; Phenylephrine; Pyridines; Rats; Rats, Wistar; Scopolamine	2004
Treatment of Wilms tumor-related hypertension with losartan and captopril. Pediatric nephrology (Berlin, Germany), 2004, Volume: 19, Issue:7 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Captopril; Humans; Hypertension; Infant; Kidney Neoplasms; Losartan; Male; Renin; Wilms Tumor	2004
Role of bradykinin B2-receptor in the sympathoadrenal effects of 'new pressor protein' related to human blood coagulation factor XII fragment. Journal of hypertension, 2004, Volume: 22, Issue:6 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Blood Proteins; Captopril; Epinephrine; Factor XII; Heart Rate; Humans; Losartan; Male; Norepinephrine; Rats; Rats, Wistar; Receptor, Bradykinin B2	2004
Differential response of human cardiac fibroblasts to angiotensin I and angiotensin II. Peptides, 2004, Volume: 25, Issue:6 Topics: Angiotensin I; Angiotensin II; Captopril; Cell Line; Collagen; Fibroblasts; Humans; Losartan; Myocardium; Peptidyl-Dipeptidase A	2004
Contribution of angiotensin II to alcohol-induced pancreatic fibrosis in rats. The Journal of pharmacology and experimental therapeutics, 2004, Volume: 311, Issue:3 Topics: Actins; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Captopril; Central Nervous System Depressants; Collagen; Cytokines; Ethanol; Fibrosis; Immunohistochemistry; Losartan; Male; Pancreas; Pancreatic Diseases; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Ribonucleases; RNA, Messenger	2004
Changes in skeletal muscle SR Ca2+ pump in congestive heart failure due to myocardial infarction are prevented by angiotensin II blockade. Canadian journal of physiology and pharmacology, 2004, Volume: 82, Issue:7 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Calcium; Calcium-Transporting ATPases; Captopril; Cyclic AMP-Dependent Protein Kinases; Enalapril; Heart Failure; Imidazolidines; Losartan; Male; Muscle, Skeletal; Muscular Atrophy; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Sarcoplasmic Reticulum; Time Factors	2004
Hemodynamic and metabolic effects of angiotensin II on the liver. Peptides, 2005, Volume: 26, Issue:2 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Glucose; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Hemodynamics; Hepatocytes; Kinetics; Kupffer Cells; Liver; Liver Circulation; Losartan; Male; Oxygen Consumption; Perfusion; Rats; Rats, Wistar	2005
Angiotensin II inhibition during myocardial ischemia-reperfusion in dogs: effects on leukocyte infiltration, nitric oxide synthase isoenzymes activity and left ventricular ejection fraction. International journal of cardiology, 2005, Apr-28, Volume: 100, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dogs; Hemodynamics; Losartan; Myocardial Reperfusion; Myocardial Reperfusion Injury; Myocardium; Nitric Oxide Synthase; Peroxidase; Stroke Volume	2005
[Effects of captopril and losartan on expression of kidney aquaporin-2 mRNA and urine aquaporin-2 excretion in rats]. Di 1 jun yi da xue xue bao = Academic journal of the first medical college of PLA, 2005, Volume: 25, Issue:4 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aquaporin 2; Captopril; Kidney; Losartan; Male; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger	2005
Integrating research and development: the emergence of rational drug design in the pharmaceutical industry. Studies in history and philosophy of biological and biomedical sciences, 2005, Volume: 36, Issue:3 Topics: Biomedical Research; Captopril; Drug Design; Drug Industry; Germany; Humans; Losartan; Propranolol; United States	2005
Confidence intervals for an exposure adjusted incidence rate difference with applications to clinical trials. Statistics in medicine, 2006, Apr-30, Volume: 25, Issue:8 Topics: Aged; Captopril; Clinical Trials as Topic; Confidence Intervals; Data Interpretation, Statistical; Follow-Up Studies; Heart Failure; Humans; Incidence; Losartan; Middle Aged; Models, Statistical; Poisson Distribution; Proportional Hazards Models	2006
Chronic angiotensin II AT1 receptor blockade increases cerebral cortical microvessel density. American journal of physiology. Heart and circulatory physiology, 2006, Volume: 290, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Blood Pressure; Blood Vessels; Captopril; Cerebral Cortex; Diuretics; Drug Administration Schedule; Drug Combinations; Furosemide; Losartan; Male; Microcirculation; Rats; Rats, Sprague-Dawley; Time Factors	2006
Angiotensin II receptor antagonists and heart failure: angiotensin-converting-enzyme inhibitors remain the first-line option. Prescrire international, 2005, Volume: 14, Issue:79 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Benzimidazoles; Captopril; Clinical Trials as Topic; Disease Progression; Drug Therapy, Combination; Heart Failure; Humans; Hypokalemia; Hypotension; Losartan; Meta-Analysis as Topic; Myocardial Infarction; Renal Insufficiency; Tetrazoles; Valine	2005
Plasma levels of soluble tumor necrosis factor receptor type I during the acute phase following complicated myocardial infarction predicts survival in high-risk patients. Journal of the American College of Cardiology, 2005, Dec-06, Volume: 46, Issue:11 Topics: Aged; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chemokine CCL2; Creatinine; Female; Heart Failure; Humans; Immunoenzyme Techniques; Interleukin-6; Losartan; Male; Middle Aged; Multivariate Analysis; Myocardial Infarction; Prognosis; Prospective Studies; Randomized Controlled Trials as Topic; Receptors, Tumor Necrosis Factor; Risk Assessment; Solubility	2005
Pressor responses to alligator Angiotensin I and some analogs in the spectacled caiman (Caiman crocodilus). General and comparative endocrinology, 2006, Volume: 147, Issue:2 Topics: Alligators and Crocodiles; Angiotensin I; Angiotensin II; Angiotensin III; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Dose-Response Relationship, Drug; Epinephrine; Losartan; Male; Norepinephrine	2006
Direct positive chronotropic action by angiotensin II in the isolated mouse atrium. Life sciences, 2006, Jul-10, Volume: 79, Issue:7 Topics: Adrenergic beta-Agonists; Adrenergic beta-Antagonists; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Dose-Response Relationship, Drug; Heart; Heart Atria; Heart Rate; In Vitro Techniques; Isoproterenol; Losartan; Male; Mice; Mice, Inbred C57BL; Nadolol; Stimulation, Chemical; Vasoconstrictor Agents	2006
Angiotensin-converting enzyme and angiotensin II receptor subtype 1 inhibitors restitute hypertensive internal anal sphincter in the spontaneously hypertensive rats. The Journal of pharmacology and experimental therapeutics, 2006, Volume: 318, Issue:2 Topics: Anal Canal; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Blotting, Western; Captopril; Hypertension; Losartan; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Rectum; Renin-Angiotensin System; Reverse Transcriptase Polymerase Chain Reaction; RNA	2006
Statin use and survival in patients with chronic heart failure--results from two observational studies with 5200 patients. International journal of cardiology, 2006, Sep-20, Volume: 112, Issue:2 Topics: Aged; Body Mass Index; Captopril; Cardiovascular Agents; Female; Heart Failure; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Male; Middle Aged; Multivariate Analysis; Oxygen Consumption; Proportional Hazards Models; Randomized Controlled Trials as Topic; Retrospective Studies; Survival Analysis	2006
Antihypertensive and renal protective effects of renin-angiotensin system blockade in uremic rats treated with erythropoietin. American journal of hypertension, 2006, Volume: 19, Issue:12 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Captopril; Disease Models, Animal; Drug Therapy, Combination; Erythropoietin; Hydralazine; Hydrochlorothiazide; Hypertension; Kidney; Kidney Failure, Chronic; Losartan; Nephrectomy; Rats; Rats, Wistar; Recombinant Proteins; Renin-Angiotensin System; Reserpine; Time Factors; Uremia	2006
Effects of poststroke losartan versus captopril treatment on myogenic and endothelial function in the cerebrovasculature of SHRsp. Stroke, 2007, Volume: 38, Issue:5 Topics: Animals; Antihypertensive Agents; Captopril; Cerebrovascular Circulation; Endothelium, Vascular; Losartan; Male; Rats; Rats, Inbred Strains; Receptor, Angiotensin, Type 1; Stroke; Vascular Diseases; Vasodilation	2007
[Inhibitory effect of angiotensin blockade on hepatic fibrosis in common bile duct-ligated rats]. The Korean journal of hepatology, 2007, Volume: 13, Issue:1 Topics: Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Bile Ducts; Captopril; Fibrosis; Hydroxyproline; Ligation; Liver; Liver Cirrhosis, Experimental; Losartan; Male; Rats; Rats, Sprague-Dawley; Transforming Growth Factor beta	2007
The effects of captopril and losartan on erythrocyte membrane Na+/K(+)-ATPase activity in experimental diabetes mellitus. Journal of enzyme inhibition and medicinal chemistry, 2007, Volume: 22, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diabetes Mellitus, Experimental; Erythrocyte Membrane; Losartan; Male; Rats; Rats, Wistar; Sodium-Potassium-Exchanging ATPase	2007
CX3CR1 receptor is up-regulated in monocytes of coronary artery diseased patients: impact of pre-inflammatory stimuli and renin-angiotensin system modulators. Thrombosis research, 2007, Volume: 121, Issue:3 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Captopril; Case-Control Studies; Cell Line; Coronary Artery Disease; CX3C Chemokine Receptor 1; Female; Humans; In Vitro Techniques; Inflammation Mediators; Interferon-gamma; Jurkat Cells; Lisinopril; Losartan; Male; Middle Aged; Monocytes; Receptors, Chemokine; Recombinant Proteins; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Up-Regulation	2007
Heart failure treatment profile at the beta blockers era. Arquivos brasileiros de cardiologia, 2007, Volume: 88, Issue:4 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Carbazoles; Carvedilol; Drug Therapy, Combination; Enalapril; Female; Heart Failure; Humans; Losartan; Male; Middle Aged; Propanolamines; Severity of Illness Index	2007
Comparison of angiotensin converting enzyme inhibition and angiotensin II receptor blockade for the prevention of experimental autoimmune myocarditis. International journal of cardiology, 2008, Mar-28, Volume: 125, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Autoantibodies; Autoimmunity; Captopril; Fibrosis; Losartan; Male; Mice; Myocarditis; Myosins	2008
Impairment of endothelium-dependent relaxation of rat aortas by homocysteine thiolactone and attenuation by captopril. Journal of cardiovascular pharmacology, 2007, Volume: 50, Issue:2 Topics: Acetylcholine; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Captopril; Dose-Response Relationship, Drug; Enalaprilat; Endothelium, Vascular; Free Radicals; Homocysteine; Losartan; Malondialdehyde; Nitric Oxide; Nitroprusside; Rats; Rats, Sprague-Dawley; Superoxide Dismutase; Vasodilation	2007
ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin. The European respiratory journal, 2008, Volume: 31, Issue:2 Topics: Angiotensin II; Animals; Apoptosis; Bradykinin; Bronchoalveolar Lavage Fluid; Captopril; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation Mediators; Losartan; Lung Diseases; Male; Peptidyl-Dipeptidase A; Pulmonary Gas Exchange; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Respiration, Artificial; Sensitivity and Specificity	2008
Captopril inhibits capillary degeneration in the early stages of diabetic retinopathy. Current eye research, 2007, Volume: 32, Issue:10 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Glucose; Body Weight; Capillaries; Captopril; Cells, Cultured; Diabetes Mellitus, Experimental; Diabetic Retinopathy; Endothelial Cells; Hyperglycemia; Leukostasis; Losartan; Male; Rats; Rats, Inbred Lew; Retina; Retinal Vessels; Vascular Cell Adhesion Molecule-1	2007
[Comparative characteristic of angiotensin-converting enzyme inhibitor--captopril and the angiotensin II receptor blokers--losartan action on the oxidative metabolism in experimental hyperlipidemia in rabbits]. Georgian medical news, 2007, Issue:150 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Catalase; Disease Models, Animal; Hyperlipidemias; Lipids; Losartan; Nitric Oxide; Oxidative Stress; Rabbits; Superoxide Dismutase; Treatment Outcome	2007
In vivo regulation of AT1a receptor-mediated intracellular uptake of [125I]Val5-ANG II in the kidneys and adrenals of AT1a receptor-deficient mice. American journal of physiology. Renal physiology, 2008, Volume: 294, Issue:2 Topics: Adrenal Cortex; Adrenal Glands; Adrenal Medulla; Aldosterone; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Captopril; Diuresis; Drinking; Endocytosis; Infusions, Intravenous; Kidney; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Knockout; Potassium; Protein Isoforms; Receptor, Angiotensin, Type 1; Sodium	2008
Meconium increases type 1 angiotensin II receptor expression and alveolar cell death. Pediatric research, 2008, Volume: 63, Issue:3 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Apoptosis; Captopril; Cell Death; Cells, Cultured; Disease Models, Animal; Humans; Immunohistochemistry; Infant, Newborn; Losartan; Male; Meconium; Meconium Aspiration Syndrome; Pulmonary Alveoli; Rabbits; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; RNA, Messenger; Up-Regulation	2008
Calcium-independent and 1,25(OH)2D3-dependent regulation of the renin-angiotensin system in 1alpha-hydroxylase knockout mice. Kidney international, 2008, Volume: 74, Issue:2 Topics: 25-Hydroxyvitamin D3 1-alpha-Hydroxylase; Animals; Antihypertensive Agents; Blood Pressure; Calcium; Captopril; Cardiomegaly; Gene Deletion; Gene Targeting; Hypertension; Losartan; Mice; Mice, Knockout; Myocytes, Cardiac; Phosphorus; Renin-Angiotensin System; Vitamin D	2008
Oestrogenic influence on brain AT1 receptor signalling on the thirst and sodium appetite in osmotically stimulated and sodium-depleted female rats. Experimental physiology, 2008, Volume: 93, Issue:8 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Brain; Captopril; Contraceptive Agents; Disease Models, Animal; Diuretics; Drinking; Estradiol; Estrogens; Female; Furosemide; Hyponatremia; Losartan; Ovariectomy; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Signal Transduction; Thirst	2008
ACE-dependent and chymase-dependent angiotensin II generation in normal and glucose-stimulated human mesangial cells. Experimental biology and medicine (Maywood, N.J.), 2008, Volume: 233, Issue:8 Topics: Angiotensin II; Captopril; Cells, Cultured; Chymases; Diabetic Nephropathies; Glucose; Humans; Losartan; Mesangial Cells; Oligopeptides; Peptidyl-Dipeptidase A; RNA, Messenger	2008
Opposed effects of prostaglandin E2 on perfusion of rat renal cortex and medulla: interactions with the renin-angiotensin system. Experimental physiology, 2008, Volume: 93, Issue:12 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cyclooxygenase Inhibitors; Dinoprostone; Indomethacin; Infusions, Intra-Arterial; Kidney Cortex; Kidney Medulla; Laser-Doppler Flowmetry; Losartan; Male; Misoprostol; Rats; Rats, Wistar; Receptors, Prostaglandin E; Receptors, Prostaglandin E, EP3 Subtype; Renal Artery; Renal Circulation; Renin-Angiotensin System; Ultrasonography; Vasoconstriction; Vasodilation	2008
RAS inhibitors decrease apoptosis of acinar cells and increase elimination of pancreatic stellate cells after in the course of experimental chronic pancreatitis induced by dibutyltin dichloride. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2008, Volume: 59 Suppl 2 Topics: Actins; Aldosterone; Animals; Apoptosis; Captopril; Cell Proliferation; Enalapril; Immunohistochemistry; Lisinopril; Losartan; Male; Organotin Compounds; Pancreas; Pancreatitis, Chronic; Rats; Rats, Inbred Lew; Renin-Angiotensin System	2008
Regulation of oxygen utilization by angiotensin II in chronic kidney disease. Kidney international, 2009, Volume: 75, Issue:2 Topics: Angiotensin II; Animals; Captopril; Disease Models, Animal; Kidney Diseases; Losartan; Nitric Oxide Synthase; Oxygen Consumption; Rats; Sodium	2009
Induction of apoptosis in leukemic cell lines treated with captopril, trandolapril and losartan: a new role in the treatment of leukaemia for these agents. Leukemia research, 2009, Volume: 33, Issue:6 Topics: Angiotensin-Converting Enzyme Inhibitors; Apoptosis; Blotting, Northern; Blotting, Western; Captopril; Cell Proliferation; Genes, myc; Humans; Indoles; K562 Cells; Leukemia, Erythroblastic, Acute; Losartan; Polymerase Chain Reaction	2009
The relationship between heart rate reserve and oxygen uptake reserve in heart failure patients on optimized and non-optimized beta-blocker therapy. Clinics (Sao Paulo, Brazil), 2008, Volume: 63, Issue:6 Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Captopril; Carbazoles; Carvedilol; Drug Therapy, Combination; Enalapril; Exercise Test; Female; Heart Failure; Heart Rate; Humans; Losartan; Male; Middle Aged; Oxygen Consumption; Propanolamines	2008
Erythropoietin levels in heart failure after an acute myocardial infarction: determinants, prognostic value, and the effects of captopril versus losartan. American heart journal, 2009, Volume: 157, Issue:1 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Captopril; Erythropoietin; Female; Heart Failure; Humans; Losartan; Male; Myocardial Infarction; Prognosis; Retrospective Studies	2009
Molecular imaging for efficacy of pharmacologic intervention in myocardial remodeling. JACC. Cardiovascular imaging, 2009, Volume: 2, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carbocyanines; Cardiovascular Agents; Disease Models, Animal; Drug Therapy, Combination; Echocardiography; Fibrillar Collagens; Fibroblasts; Fibrosis; Losartan; Mice; Mineralocorticoid Receptor Antagonists; Myocardial Infarction; Myocardium; Oligopeptides; Predictive Value of Tests; Spironolactone; Technetium; Tomography, Emission-Computed, Single-Photon; Ventricular Function, Left; Ventricular Remodeling	2009
Losartan decreases p42/44 MAPK signaling and preserves LZ+ MYPT1 expression. PloS one, 2009, Volume: 4, Issue:4 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta; Captopril; Enzyme Activation; Heart Failure; Humans; Isoenzymes; Losartan; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Muscle, Smooth, Vascular; Myocardial Infarction; p38 Mitogen-Activated Protein Kinases; Protein Phosphatase 1; Rats; Rats, Sprague-Dawley; Ventricular Function, Left	2009
Involvement of central angiotensin II type 1 receptors in LPS-induced systemic vasopressin release and blood pressure regulation in rats. Journal of applied physiology (Bethesda, Md. : 1985), 2009, Volume: 106, Issue:6 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine Vasopressin; Blood Pressure; Captopril; Disease Models, Animal; Drug Therapy, Combination; Endotoxemia; Injections, Intraventricular; Injections, Subcutaneous; Lipopolysaccharides; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2	2009
Primary aldosteronism: diagnostic accuracy of the losartan and captopril tests. American journal of hypertension, 2009, Volume: 22, Issue:8 Topics: Adult; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Area Under Curve; Captopril; Cohort Studies; Diagnosis, Differential; Female; Humans; Hyperaldosteronism; Losartan; Male; Middle Aged; Prospective Studies; Reproducibility of Results; ROC Curve; Taiwan; Tomography, X-Ray Computed	2009
[Changes of MMP-2,9 and TIMP-1 expressions in rats with pulmonary arterial hypertension after captopril and losartan interventions]. Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition, 2009, Volume: 40, Issue:2 Topics: Animals; Captopril; Hypertension, Pulmonary; Losartan; Male; Matrix Metalloproteinase 2; Matrix Metalloproteinase 9; Random Allocation; Rats; Rats, Sprague-Dawley; RNA, Messenger; Tissue Inhibitor of Metalloproteinase-1	2009
Synergistic decrease in blood pressure by captopril combined with losartan in spontaneous hypertensive rats. Archives of pharmacal research, 2009, Volume: 32, Issue:6 Topics: Administration, Oral; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cross-Over Studies; Drug Synergism; Drug Therapy, Combination; Losartan; Male; Random Allocation; Rats; Rats, Inbred SHR; Time Factors	2009
Acquisition of the contractile phenotype by murine arterial smooth muscle cells depends on the Mir143/145 gene cluster. The Journal of clinical investigation, 2009, Volume: 119, Issue:9 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Base Sequence; Captopril; Humans; In Vitro Techniques; Losartan; Mice; Mice, Inbred C57BL; Mice, Knockout; MicroRNAs; Multigene Family; Muscle Contraction; Myocytes, Smooth Muscle; Oligonucleotide Array Sequence Analysis; Phenotype; Tunica Intima	2009
Production and secretion of adiponectin from 3T3-L1 adipocytes: comparison of antihypertensive drugs. American journal of hypertension, 2009, Volume: 22, Issue:10 Topics: 3T3-L1 Cells; Adipocytes; Adiponectin; Animals; Antihypertensive Agents; Atenolol; Benzimidazoles; Benzoates; Captopril; Hydrochlorothiazide; Losartan; Mice; Nifedipine; RNA, Messenger; Telmisartan	2009
Comparative study of vasodilators in an animal model of chronic volume overload caused by severe aortic regurgitation. Circulation. Heart failure, 2009, Volume: 2, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aortic Valve Insufficiency; Captopril; Cardiomyopathy, Dilated; Chronic Disease; Disease Models, Animal; Dose-Response Relationship, Drug; Echocardiography, Doppler; Follow-Up Studies; Hypertrophy, Left Ventricular; Losartan; Male; Nifedipine; Rats; Rats, Wistar; Renin-Angiotensin System; Treatment Outcome; Vasodilator Agents; Ventricular Function, Left	2009
Optimising management of chronic heart failure. Lancet (London, England), 2009, Nov-28, Volume: 374, Issue:9704 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Captopril; Chronic Disease; Dose-Response Relationship, Drug; Heart Failure; Humans; Losartan; Renin-Angiotensin System	2009
Renin-Angiotensin system suppression mitigates experimental radiation pneumonitis. International journal of radiation oncology, biology, physics, 2009, Dec-01, Volume: 75, Issue:5 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Drug Evaluation, Preclinical; Female; Losartan; Lung; Pulmonary Artery; Radiation Dosage; Radiation Injuries, Experimental; Radiation Pneumonitis; Rats; Renin-Angiotensin System; Respiratory Mechanics; Time Factors; Vasoconstriction; Vasodilation	2009
FURO/CAP: a protocol for sodium intake sensitization. Physiology & behavior, 2010, Mar-30, Volume: 99, Issue:4 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Appetite; Behavior, Animal; Captopril; Diuretics; Dose-Response Relationship, Drug; Drinking; Drug Combinations; Furosemide; Losartan; Male; Rats; Sodium Chloride; Water Deprivation	2010
Ventilator-induced inflammatory response in lipopolysaccharide-exposed rat lung is mediated by angiotensin-converting enzyme. The American journal of pathology, 2010, Volume: 176, Issue:5 Topics: Animals; Bronchoalveolar Lavage Fluid; Captopril; Chemokine CXCL2; Inflammation; Interleukin-10; Interleukin-1beta; Interleukin-6; Lipopolysaccharides; Losartan; Lung; Male; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Respiration, Artificial	2010
Availability, price and affordability of cardiovascular medicines: a comparison across 36 countries using WHO/HAI data. BMC cardiovascular disorders, 2010, Jun-09, Volume: 10 Topics: Antihypertensive Agents; Atenolol; Captopril; Cardiovascular Diseases; Cost of Illness; Developing Countries; Health Services Accessibility; Humans; Hydrochlorothiazide; Losartan; Nifedipine; World Health Organization	2010
A consistency-adjusted alpha-adaptive strategy for sequential testing. Statistics in medicine, 2010, Jul-10, Volume: 29, Issue:15 Topics: Algorithms; Biostatistics; Captopril; Clinical Trials as Topic; Data Interpretation, Statistical; Diabetic Angiopathies; Endpoint Determination; Epidemiologic Research Design; Heart Failure; Humans; Losartan; Pioglitazone; Randomized Controlled Trials as Topic; Thiazolidinediones	2010
The effects of poststroke captopril and losartan treatment on cerebral blood flow autoregulation in SHRsp with hemorrhagic stroke. Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2011, Volume: 31, Issue:2 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Blood-Brain Barrier; Brain; Captopril; Cerebral Hemorrhage; Cerebrovascular Circulation; Diet; Homeostasis; Losartan; Middle Cerebral Artery; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Stroke; Vasoconstriction	2011
Mitigating effects of captopril and losartan on lung histopathology in a rat model of fat embolism. The Journal of trauma, 2011, Volume: 70, Issue:5 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Drug Therapy, Combination; Embolism, Fat; Losartan; Lung; Rats; Rats, Sprague-Dawley; Treatment Outcome	2011
Impaired relaxation of cerebral arteries in the absence of elevated salt intake in normotensive congenic rats carrying the Dahl salt-sensitive renin gene. American journal of physiology. Heart and circulatory physiology, 2010, Volume: 299, Issue:6 Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Congenic; Antioxidants; Blood Pressure; Captopril; Crosses, Genetic; Cyclic N-Oxides; Dose-Response Relationship, Drug; Enzyme Inhibitors; Infusions, Intravenous; Losartan; Male; Middle Cerebral Artery; NG-Nitroarginine Methyl Ester; Nitric Oxide; Rats; Rats, Inbred BN; Rats, Inbred Dahl; Renin; Renin-Angiotensin System; Sodium Chloride, Dietary; Spin Labels; Superoxides; Vasodilation; Vasodilator Agents	2010
The frequency of factor V Leiden mutation, ACE gene polymorphism, serum ACE activity and response to ACE inhibitor and angiotensin II receptor antagonist drugs in Iranians type II diabetic patients with microalbuminuria. Molecular biology reports, 2011, Volume: 38, Issue:3 Topics: Albuminuria; Alleles; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Factor V; Female; Genetic Predisposition to Disease; Humans; Iran; Losartan; Male; Middle Aged; Mutation; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Treatment Outcome	2011
Effects of angiotensin III on protein, DNA, and collagen synthesis of neonatal cardiomyocytes and cardiac fibroblasts in vitro. Journal of cardiovascular pharmacology and therapeutics, 2010, Volume: 15, Issue:4 Topics: Angiotensin II; Angiotensin III; Animals; Animals, Newborn; Captopril; Cell Proliferation; Cells, Cultured; Collagen; DNA; Fibroblasts; Heart; Losartan; Male; Methionine; Myocardium; Myocytes, Cardiac; Rats; Rats, Wistar; Sulfonic Acids	2010
Blockade of the renin-angiotensin system ameliorates apelin production in 3T3-L1 adipocytes. Cardiovascular drugs and therapy, 2011, Volume: 25, Issue:1 Topics: 3T3-L1 Cells; Adipocytes; Adipokines; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensinogen; Animals; Apelin; Captopril; Cells, Cultured; Imidazoles; Intercellular Signaling Peptides and Proteins; Lipid Metabolism; Losartan; Mice; Perindopril; Pyridines; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin; Renin-Angiotensin System; RNA, Messenger	2011
Captopril and losartan for mitigation of renal injury caused by single-dose total-body irradiation. Radiation research, 2011, Volume: 175, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Azotemia; Captopril; Hypertension; Kidney; Linear Models; Losartan; Male; Proteinuria; Radiation Injuries; Rats; Renal Insufficiency; United States; United States Food and Drug Administration; Whole-Body Irradiation	2011
Anti-inflammatory effects of anti-hypertensive agents: influence on interleukin-1β secretion by peripheral blood polymorphonuclear leukocytes from patients with essential hypertension. Clinical and experimental hypertension (New York, N.Y. : 1993), 2011, Volume: 33, Issue:2 Topics: Adult; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Atenolol; Captopril; Case-Control Studies; Female; Humans; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Losartan; Male; Middle Aged; Neutrophils	2011
Comparison of angiotensin converting enzyme inhibitors and angiotensin II type 1 receptor blockade for the prevention of premalignant changes in the liver. Life sciences, 2011, Aug-01, Volume: 89, Issue:5-6 Topics: alpha-Fetoproteins; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Anticarcinogenic Agents; Captopril; Carcinoembryonic Antigen; Endostatins; Enzyme-Linked Immunosorbent Assay; Fibroblast Growth Factors; Hydroxyproline; Liver; Liver Neoplasms, Experimental; Losartan; Male; Matrix Metalloproteinase 2; Metallothionein; Perindopril; Precancerous Conditions; Rats; Transforming Growth Factor beta1; Vascular Endothelial Growth Factor A	2011
AT₁ receptor blockade in the lateral parabrachial nucleus reduces the effects of muscimol on sodium intake. Brain research, 2011, Jul-27, Volume: 1403 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diuretics; Drinking Behavior; Furosemide; GABA-A Receptor Agonists; Losartan; Male; Muscimol; Pons; Rats; Rats, Wistar; Sodium Chloride	2011
Increased oxidative stress, the renin-angiotensin system, and sympathetic overactivation induce hypertension in kidney androgen-regulated protein transgenic mice. Free radical biology & medicine, 2011, Nov-15, Volume: 51, Issue:10 Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Cyclic N-Oxides; Hypertension; Kidney; Losartan; Male; Mice; Mice, Inbred C57BL; Mice, Transgenic; Norepinephrine; Oxidative Stress; Proteins; Renin-Angiotensin System; Spin Labels; Sympathetic Nervous System; Transgenes	2011
Natriorexigenic effect of baclofen is reduced by AT₁ receptor blockade in the lateral parabrachial nucleus. Brain research bulletin, 2011, Nov-25, Volume: 86, Issue:5-6 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Baclofen; Captopril; Diuretics; Drinking; Drinking Behavior; Furosemide; GABA-B Receptor Agonists; Losartan; Male; Pons; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sodium Chloride	2011
Effects of captopril and angiotensin II receptor blockers (AT1, AT2) on myocardial ischemia-reperfusion induced infarct size. Cytokine, 2011, Volume: 56, Issue:3 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arteries; Blood Pressure; Captopril; Heart Rate; Imidazoles; Losartan; Male; Myocardial Infarction; Myocardial Reperfusion Injury; Myocardium; Necrosis; Pyridines; Rats; Rats, Wistar; Risk Factors	2011
Effects of antihypertensive drugs on specific harmonic indices of the pulse waveform in normotensive Wistar Kyoto rats. Clinical and experimental hypertension (New York, N.Y. : 1993), 2012, Volume: 34, Issue:1 Topics: Animals; Antihypertensive Agents; Atenolol; Blood Pressure; Captopril; Losartan; Male; Models, Animal; Models, Cardiovascular; Pulsatile Flow; Rats; Rats, Inbred WKY	2012
Characterization of Angiotensin-(1-7) effects on the cardiovascular system in an experimental model of type-1 diabetes. Pharmacological research, 2012, Volume: 66, Issue:3 Topics: Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme 2; Animals; Captopril; Cardiovascular System; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Disease Models, Animal; Endothelin-1; Hyperglycemia; Kidney; Losartan; Male; NADPH Oxidases; Peptide Fragments; Peptides; Peptidyl-Dipeptidase A; Prostaglandins; Proto-Oncogene Mas; Proto-Oncogene Proteins; Rats; Rats, Wistar; Receptors, G-Protein-Coupled; Reperfusion Injury	2012
A brain leptin-renin angiotensin system interaction in the regulation of sympathetic nerve activity. American journal of physiology. Heart and circulatory physiology, 2012, Jul-15, Volume: 303, Issue:2 Topics: Adipose Tissue; alpha-MSH; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Body Weight; Brain; Captopril; Corticotropin-Releasing Hormone; Eating; Gene Deletion; Leptin; Losartan; Male; Mice; Mice, Inbred C57BL; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Sympathetic Nervous System	2012
The involvement of angiotensin type 1 and type 2 receptors in estrogen-induced cell proliferation and vascular endothelial growth factor expression in the rat anterior pituitary. TheScientificWorldJournal, 2012, Volume: 2012 Topics: Animals; Captopril; Cell Proliferation; Diethylstilbestrol; Estrogens; Gene Expression Regulation; Hyperplasia; Imidazoles; Immunohistochemistry; Losartan; Male; Neovascularization, Pathologic; Pituitary Gland, Anterior; Pyridines; Rats; Rats, Inbred F344; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vascular Endothelial Growth Factor A	2012
Angiotensin-(1-12) in the rostral ventrolateral medullary pressor area of the rat elicits sympathoexcitatory responses. Experimental physiology, 2013, Volume: 98, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Arterial Pressure; Captopril; Chymases; Imidazoles; Losartan; Male; Medulla Oblongata; Oligopeptides; Paraventricular Hypothalamic Nucleus; Peptide Fragments; Peptidyl-Dipeptidase A; Phenylethanolamine N-Methyltransferase; Pyridines; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Sympathetic Nervous System	2013
Involvement of central cholinergic mechanisms on sodium intake induced by gabaergic activation of the lateral parabrachial nucleus. Neuroscience letters, 2013, Feb-08, Volume: 534 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Atropine; Captopril; Diuretics; Drinking; Eating; Furosemide; GABA Agonists; Imidazoles; Injections, Intraventricular; Losartan; Male; Muscarinic Antagonists; Muscimol; Pons; Rats; Rats, Sprague-Dawley; Receptors, GABA-A; Receptors, Muscarinic; Sodium Chloride	2013
Inhibition of central angiotensin II enhances memory function and reduces oxidative stress status in rat hippocampus. Progress in neuro-psychopharmacology & biological psychiatry, 2013, Jun-03, Volume: 43 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Avoidance Learning; Behavior, Animal; Captopril; Glutathione Peroxidase; Hippocampus; Imidazoles; Lipid Peroxidation; Losartan; Male; Malondialdehyde; Maze Learning; Memory; Memory, Short-Term; Oxidative Stress; Psychomotor Performance; Pyridines; Rats; Rats, Wistar; Superoxide Dismutase	2013
Combined treatment with gabapentin and drugs affecting the renin-angiotensin system against electroconvulsions in mice. European journal of pharmacology, 2013, Apr-15, Volume: 706, Issue:1-3 Topics: Amines; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Anticonvulsants; Avoidance Learning; Benzimidazoles; Benzoates; Brain; Captopril; Cyclohexanecarboxylic Acids; Drug Therapy, Combination; Electroshock; Enalapril; Gabapentin; gamma-Aminobutyric Acid; Losartan; Male; Mice; Motor Skills; Seizures; Telmisartan	2013
Angiotensin-converting enzyme-induced activation of local angiotensin signaling is required for ascending aortic aneurysms in fibulin-4-deficient mice. Science translational medicine, 2013, May-01, Volume: 5, Issue:183 Topics: Angiotensin II; Animals; Aorta; Aortic Aneurysm; Biomarkers; Biomechanical Phenomena; Blood Pressure; Captopril; Cell Differentiation; Extracellular Matrix Proteins; Extracellular Signal-Regulated MAP Kinases; Gene Deletion; Losartan; Male; Mice; Mice, Knockout; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Peptidyl-Dipeptidase A; Phenotype; Phosphorylation; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Signal Transduction; Time Factors; Up-Regulation	2013
Renin angiotensin system blockade ameliorates lead nephropathy. Biochemical and biophysical research communications, 2013, Aug-23, Volume: 438, Issue:2 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Gene Expression Regulation; Glomerular Filtration Rate; Kidney Diseases; Lead Poisoning; Losartan; Male; Peptidyl-Dipeptidase A; Proteinuria; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Renin-Angiotensin System; Transforming Growth Factor beta	2013
RU28318, an aldosterone antagonist, in combination with an ACE inhibitor and angiotensin receptor blocker attenuates cardiac dysfunction in diabetes. Journal of diabetes research, 2013, Volume: 2013 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diabetes Mellitus, Experimental; Drug Therapy, Combination; Heart; Losartan; Male; Mineralocorticoid Receptor Antagonists; Myocardial Ischemia; Myocardial Reperfusion Injury; Rats; Rats, Wistar; Spironolactone	2013
Measuring angiotensin-I converting enzyme inhibitory activity by micro plate assays: comparison using marine cryptides and tentative threshold determinations with captopril and losartan. Journal of agricultural and food chemistry, 2013, Nov-13, Volume: 61, Issue:45 Topics: Angiotensin-Converting Enzyme Inhibitors; Captopril; Enzyme Assays; Losartan; Peptide Fragments; Peptidyl-Dipeptidase A	2013
Cardiovascular effect of angiotensin-(1-12) in the caudal ventrolateral medullary depressor area of the rat. American journal of physiology. Heart and circulatory physiology, 2014, Volume: 306, Issue:3 Topics: Adrenergic alpha-1 Receptor Agonists; Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Captopril; Heart Rate; Losartan; Male; Medulla Oblongata; Nitroprusside; Peptide Fragments; Phenylephrine; Rats; Rats, Wistar; Vasomotor System	2014
Roles of hypertension in the rupture of intracranial aneurysms. Stroke, 2014, Volume: 45, Issue:2 Topics: Aneurysm, Ruptured; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Desoxycorticosterone Acetate; Dose-Response Relationship, Drug; Hydralazine; Hypertension; Intracranial Aneurysm; Losartan; Male; Mice; Mice, Inbred C57BL; Pancreatic Elastase; Renin-Angiotensin System; Risk Factors; Subarachnoid Hemorrhage; Survival Analysis; Treatment Outcome	2014
Natriorexigenic effect of DAMGO is decreased by blocking AT1 receptors in the central nucleus of the amygdala. Neuroscience, 2014, Mar-14, Volume: 262 Topics: Amygdala; Analgesics, Opioid; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Diuretics; Drinking Behavior; Enkephalin, Ala(2)-MePhe(4)-Gly(5)-; Furosemide; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Sodium Chloride, Dietary; Time Factors; Water; Water Deprivation	2014
Measuring, reversing, and modeling the mechanical changes due to the absence of Fibulin-4 in mouse arteries. Biomechanics and modeling in mechanobiology, 2014, Volume: 13, Issue:5 Topics: Animals; Aorta; Arteries; Biomechanical Phenomena; Captopril; Collagen; Elastic Modulus; Elastin; Extracellular Matrix Proteins; Female; Losartan; Male; Mice, Knockout; Models, Cardiovascular; Organ Specificity; Pressure; Stress, Mechanical	2014
A novel design of combining the angiotensin converting enzyme (ACE) inhibitor captopril with the angiotensin receptor blocker (ARB) losartan using homo coupling via PEG diacid linker. Recent patents on cardiovascular drug discovery, 2013, Volume: 8, Issue:3 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Captopril; Drug Combinations; Drug Design; Humans; Losartan; Polyethylene Glycols	2013
Blockade of renin-angiotensin system prevents micturition dysfunction in renovascular hypertensive rats. European journal of pharmacology, 2014, Sep-05, Volume: 738 Topics: Adrenergic beta-Antagonists; Angiotensin II; Animals; Antihypertensive Agents; Atenolol; Blood Pressure; Body Weight; Captopril; Cyclic AMP; Electric Stimulation; Female; Hypertension, Renovascular; Losartan; Male; Muscle Relaxation; Rats; Renin-Angiotensin System; Urethra; Urinary Bladder; Urination	2014
The role of captopril and losartan in prevention and regression of tamoxifen-induced resistance of breast cancer cell line MCF-7: an in vitro study. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2014, Volume: 68, Issue:5 Topics: Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasms; Captopril; Cell Proliferation; Cell Shape; Drug Resistance, Neoplasm; Female; Gene Expression Regulation, Neoplastic; Humans; Losartan; MCF-7 Cells; Remission Induction; Renin-Angiotensin System; RNA, Messenger; Tamoxifen	2014
Uremic conditions drive human monocytes to pro-atherogenic differentiation via an angiotensin-dependent mechanism. PloS one, 2014, Volume: 9, Issue:7 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Atherosclerosis; Captopril; Cell Adhesion; Cell Line; Cell Movement; Cell Proliferation; Humans; Lipopolysaccharides; Losartan; Monocytes; Peptidyl-Dipeptidase A; Uremia	2014
The value of losartan suppression test in the confirmatory diagnosis of primary aldosteronism in patients over 50 years old. Journal of the renin-angiotensin-aldosterone system : JRAAS, 2015, Volume: 16, Issue:3 Topics: Aldosterone; Captopril; Demography; Female; Humans; Hyperaldosteronism; Hypertension; Losartan; Male; Middle Aged; Renin; Reproducibility of Results; ROC Curve	2015
Acute hemodynamic effects of angiotensin- converting enzyme inhibition after prolonged cardiac arrest with Bretschneider's solution. Naunyn-Schmiedeberg's archives of pharmacology, 2014, Volume: 387, Issue:12 Topics: Adenosine Triphosphate; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Endothelin Receptor Antagonists; Glucose; Heart Arrest; Hemodynamics; Losartan; Male; Malondialdehyde; Mannitol; Myocardial Reperfusion Injury; Oxygen Consumption; Peptides, Cyclic; Potassium Chloride; Procaine; Rabbits	2014
Combining use of captopril and losartan attenuates the progress of Streptococcus pneumoniae-induced tympanosclerosis through the suppression of TGF-β1 expression. PloS one, 2014, Volume: 9, Issue:10 Topics: Animals; Blotting, Western; Calcinosis; Calcium; Captopril; Disease Models, Animal; Disease Progression; Drug Therapy, Combination; Ear, Middle; Guinea Pigs; Hearing; Immunohistochemistry; Losartan; Male; Mucous Membrane; Myringosclerosis; Rats, Wistar; Streptococcus pneumoniae; Transforming Growth Factor beta1	2014
Intracerebroventricular infusion of the (Pro)renin receptor antagonist PRO20 attenuates deoxycorticosterone acetate-salt-induced hypertension. Hypertension (Dallas, Tex. : 1979), 2015, Volume: 65, Issue:2 Topics: Angiotensin II; Animals; Antihypertensive Agents; Baroreflex; Binding, Competitive; Blood Pressure; Calcium; Captopril; Cell Line, Tumor; Desoxycorticosterone Acetate; Extracellular Signal-Regulated MAP Kinases; Humans; Hypertension; Hypothalamus; Infusions, Intraventricular; Ion Transport; Losartan; Mice; Mice, Inbred C57BL; Neuroblastoma; Peptide Fragments; Phosphorylation; Prorenin Receptor; Protein Processing, Post-Translational; Receptors, Cell Surface; Renin; Sodium Chloride; Vacuolar Proton-Translocating ATPases	2015
Comparing individual angiotensin-converting enzyme inhibitors with losartan in the risk of hospitalization for pneumonia and related mortality: a nationwide cohort study. Journal of hypertension, 2015, Volume: 33, Issue:3 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cohort Studies; Enalapril; Female; Hospitalization; Humans; Incidence; Losartan; Male; Middle Aged; Pneumonia; Ramipril; Risk; Taiwan	2015
Elevated pressure causes endothelial dysfunction in mouse carotid arteries by increasing local angiotensin signaling. American journal of physiology. Heart and circulatory physiology, 2015, Feb-15, Volume: 308, Issue:4 Topics: Acetylcholine; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Carotid Arteries; Endothelium, Vascular; Hydrazines; Hypertension; Indoles; Losartan; Male; Mice; Mice, Inbred C57BL; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase Type III; Reactive Oxygen Species; Signal Transduction; Tetrazoles; Valine; Valsartan; Vasodilation	2015
Renin-angiotensin system (RAS) blockade attenuates growth and metastatic potential of renal cell carcinoma in mice. Urologic oncology, 2015, Volume: 33, Issue:9 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Carcinoma, Renal Cell; Disease Models, Animal; Immunohistochemistry; Kidney Neoplasms; Losartan; Mice; Mice, Inbred BALB C; Neovascularization, Pathologic; Renin-Angiotensin System	2015
Profibrosing effect of angiotensin converting enzyme inhibitors in human lung fibroblasts. Lung, 2015, Volume: 193, Issue:2 Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Captopril; Cells, Cultured; Collagen Type I; Collagen Type I, alpha 1 Chain; Enalapril; Fibroblasts; Fibrosis; Fumarates; Humans; Losartan; Lung; Protein Biosynthesis; Renin; Transcription, Genetic; Transforming Growth Factor beta1	2015
Losartan and Sodium Nitroprusside Effectively Protect against Renal Impairments after Ischemia and Reperfusion in Rats. Biological & pharmaceutical bulletin, 2015, Volume: 38, Issue:5 Topics: Adenosine Triphosphatases; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Arginine; Captopril; Ischemia; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide Donors; Nitroprusside; Peptides, Cyclic; Rats, Wistar; Renal Insufficiency; Reperfusion; Reperfusion Injury	2015
Angiotensin Receptor Blocker Losartan Inhibits Spontaneous Motility of Isolated Human Ureter. European journal of drug metabolism and pharmacokinetics, 2016, Volume: 41, Issue:6 Topics: Aged; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Captopril; Carcinoma, Renal Cell; Enalapril; Female; Humans; In Vitro Techniques; Losartan; Male; Middle Aged; Muscle Contraction; Osmolar Concentration; Ureter	2016
Effects of angiotensin II on leptin and downstream leptin signaling in the carotid body during acute intermittent hypoxia. Neuroscience, 2015, Dec-03, Volume: 310 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Captopril; Carotid Body; Hypoxia, Brain; Leptin; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptors, Leptin; Signal Transduction	2015
Losartan and captopril treatment rescue normal thrombus formation in microfibril associated glycoprotein-1 (MAGP1) deficient mice. Thrombosis research, 2016, Volume: 138 Topics: Animals; Antihypertensive Agents; Captopril; Carotid Arteries; Contractile Proteins; Extracellular Matrix Proteins; Gelatinases; Gene Deletion; Losartan; Male; Mice; Mice, Inbred C57BL; Platelet Aggregation; Platelet Function Tests; RNA Splicing Factors; Thrombosis; Transforming Growth Factor beta	2016
Renin-angiotensin system blockers regulate the metabolism of isolated fat cells in vitro. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2016, Jul-28, Volume: 49, Issue:8 Topics: Adipocytes; Amides; Animals; Antihypertensive Agents; Captopril; Fumarates; Glucose; Glycerol; Lipogenesis; Lipolysis; Losartan; Male; Rats, Wistar; Renin-Angiotensin System	2016
Mechanical activation of angiotensin II type 1 receptors causes actin remodelling and myogenic responsiveness in skeletal muscle arterioles. The Journal of physiology, 2016, 12-01, Volume: 594, Issue:23 Topics: Abdominal Muscles; Actins; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Arterioles; Benzimidazoles; Biphenyl Compounds; Captopril; Cells, Cultured; Diglycerides; Imidazoles; Indoles; Losartan; Male; Maleimides; Muscle Development; Muscle Fibers, Skeletal; Pressure; Protein Kinase C; Pyridines; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Tetrazoles; Vasoconstriction; Vasoconstrictor Agents	2016
Facilitation by the renin-angiotensin system of cyclosporine-evoked hypertension in rats: Role of arterial baroreflexes and vasoreactivity. Life sciences, 2016, Oct-15, Volume: 163 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II; Animals; Aorta; Atrasentan; Baroreflex; Blood Pressure; Captopril; Cyclosporine; Hypertension; Indomethacin; Losartan; Male; Naphthalenes; Nitric Oxide Synthase Type III; Nitroprusside; Oligopeptides; Phenylephrine; Piperidines; Propionates; Pyrrolidines; Rats; Renin-Angiotensin System; Vasoconstriction; Vasodilation	2016
Atorvastatin, Losartan and Captopril Lead to Upregulation of TGF-β, and Downregulation of IL-6 in Coronary Artery Disease and Hypertension. PloS one, 2016, Volume: 11, Issue:12 Topics: Antihypertensive Agents; Atorvastatin; Captopril; Coronary Artery Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Inflammation; Interleukin-6; Interleukin-8; Iran; Losartan; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha; Up-Regulation	2016
Influence of antihypertensive drugs on aortic and coronary effects of Ang-(1-7) in pressure-overloaded rats. Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas, 2017, Mar-23, Volume: 50, Issue:4 Topics: Amlodipine; Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Abdominal; Blood Pressure; Calcium Channel Blockers; Captopril; Coronary Vessels; Losartan; Male; Mineralocorticoid Receptor Antagonists; Models, Animal; Peptide Fragments; Rats, Wistar; Reproducibility of Results; Spironolactone; Time Factors; Vasoconstriction; Vasodilation	2017
Thymoquinone ameliorates renal damage in unilateral ureteral obstruction in rats. Pharmacological reports : PR, 2017, Volume: 69, Issue:4 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Benzoquinones; Biomarkers; Captopril; Chemokine CCL2; Gene Expression Regulation; Kidney; Kidney Diseases; Losartan; Male; Oxidative Stress; Rats; Rats, Wistar; Sulfhydryl Compounds; Ureteral Obstruction	2017
Cerebrovascular recovery after stroke with individual and combined losartan and captopril treatment of SHRsp. Vascular pharmacology, 2017, Volume: 96-98 Topics: Aldosterone; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Captopril; Cerebrovascular Circulation; Disease Models, Animal; Drug Combinations; Enzyme Activation; Hypertension; Infarction, Middle Cerebral Artery; Losartan; Middle Cerebral Artery; Nitric Oxide; Protein Kinase C; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Time Factors; Urea; Uric Acid; Vasoconstriction	2017
Apocynin combined with drugs as coadjuvant could be employed to prevent and/or treat the chronic kidney disease. Renal failure, 2018, Volume: 40, Issue:1 Topics: Acetophenones; Adjuvants, Pharmaceutic; Animals; Antihypertensive Agents; Antioxidants; Blood Pressure; Captopril; Disease Models, Animal; Disease Progression; Drug Synergism; Drug Therapy, Combination; Endothelium, Vascular; Humans; Losartan; Mice; Mice, Inbred C57BL; Oxidative Stress; Renal Insufficiency, Chronic; Treatment Outcome	2018
Antidepressant-like effect of losartan involves TRKB transactivation from angiotensin receptor type 2 (AGTR2) and recruitment of FYN. Neuropharmacology, 2018, Volume: 135 Topics: Angiotensin II; Angiotensin II Type 2 Receptor Blockers; Animals; Antidepressive Agents; Captopril; Carbazoles; Cells, Cultured; Cerebral Cortex; Enalapril; Hippocampus; Imidazoles; Immobility Response, Tonic; Indole Alkaloids; Losartan; Male; Mice; Microinjections; Prefrontal Cortex; Proto-Oncogene Proteins c-fyn; Pyridines; Rats; Receptor, Angiotensin, Type 2; Receptor, trkB; Transcriptional Activation	2018
Angiotensin receptor signaling in sickle cell anemia has a reno-protective effect on urine concentrating ability but results in sickle glomerulopathy. American journal of hematology, 2018, Volume: 93, Issue:7 Topics: Adult; Anemia, Sickle Cell; Angiotensin II Type 1 Receptor Blockers; Animals; Captopril; Child; Disease Progression; Humans; Kidney Concentrating Ability; Kidney Diseases; Losartan; Mice; Protective Agents; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Signal Transduction	2018
Atorvastatin, losartan and captopril may upregulate IL-22 in hypertension and coronary artery disease; the role of gene polymorphism. Life sciences, 2018, Aug-15, Volume: 207 Topics: Adult; Aged; Atorvastatin; Captopril; Case-Control Studies; Coronary Artery Disease; Female; Genotype; Humans; Hypertension; Interleukin-22; Interleukins; Iran; Losartan; Male; Middle Aged; Polymorphism, Genetic; Polymorphism, Single Nucleotide; Up-Regulation	2018
Nigella sativa extract is a potent therapeutic agent for renal inflammation, apoptosis, and oxidative stress in a rat model of unilateral ureteral obstruction. Phytotherapy research : PTR, 2018, Volume: 32, Issue:11 Topics: Angiotensin II; Animals; Apoptosis; Captopril; Chemokine CCL2; Creatinine; Fibrosis; Inflammation; Kidney; Kidney Diseases; Losartan; Male; Malondialdehyde; Nigella sativa; Oxidative Stress; Plant Extracts; Rats; Rats, Wistar; Renin-Angiotensin System; Tumor Necrosis Factor-alpha; Urea; Ureteral Obstruction	2018
Cytotoxic and genotoxic effects of antihypertensives distributed in Brazil by social programs: Are they safe? Environmental toxicology and pharmacology, 2018, Volume: 63 Topics: Antihypertensive Agents; Atenolol; Brazil; Captopril; Cell Survival; Cells, Cultured; DNA Damage; Dose-Response Relationship, Drug; Enalapril; Government Programs; Humans; Hydrochlorothiazide; Hypertension; Losartan; Lymphocytes; Macrophages; Male; Mutagenicity Tests; Program Evaluation; Propranolol	2018
Post-stroke losartan and captopril treatments arrest hemorrhagic expansion in SHRsp without lowering blood pressure. Vascular pharmacology, 2018, Volume: 111 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Brain Edema; Captopril; Cerebral Hemorrhage; Cerebrum; Disease Models, Animal; Disease Progression; Losartan; Male; Rats, Inbred WKY; Renin-Angiotensin System; Serum Albumin; Stroke; Time Factors	2018
The angiotensin II/AT1 receptor pathway mediates malaria-induced acute kidney injury. PloS one, 2018, Volume: 13, Issue:9 Topics: Acute Kidney Injury; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Kidney; Losartan; Malaria; Male; Mice, Inbred C57BL; Plasmodium berghei; Random Allocation; Receptor, Angiotensin, Type 1	2018
Exosome-Mediated Transfer of ACE (Angiotensin-Converting Enzyme) From Adventitial Fibroblasts of Spontaneously Hypertensive Rats Promotes Vascular Smooth Muscle Cell Migration. Hypertension (Dallas, Tex. : 1979), 2018, Volume: 72, Issue:4 Topics: Adventitia; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aniline Compounds; Animals; Benzylidene Compounds; Captopril; Cell Movement; Exosomes; Fibroblasts; Gene Knockdown Techniques; Hypertension; Losartan; Muscle, Smooth, Vascular; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Vascular Remodeling	2018
Combined Antihypertensive Therapies That Increase Expression of Cardioprotective Biomarkers Associated With the Renin-Angiotensin and Kallikrein-Kinin Systems. Journal of cardiovascular pharmacology, 2018, Volume: 72, Issue:6 Topics: Adrenergic beta-Antagonists; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Blood Pressure; Captopril; Disease Models, Animal; Gene Expression Regulation; Hypertension; Kallikrein-Kinin System; Losartan; Male; Propranolol; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B1; Receptor, Bradykinin B2; Renin-Angiotensin System; RNA, Messenger	2018
Reversal of Aortic Enlargement Induced by Increased Biomechanical Forces Requires AT1R Inhibition in Conjunction With AT2R Activation. Arteriosclerosis, thrombosis, and vascular biology, 2019, Volume: 39, Issue:3 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta; Aortic Aneurysm; Aortitis; Biomechanical Phenomena; Captopril; Constriction; Hypertension; Imidazoles; Losartan; Male; Mice; Mice, Inbred C57BL; Proto-Oncogene Mas; Proto-Oncogene Proteins; Pyridines; Random Allocation; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, G-Protein-Coupled; Renin-Angiotensin System; Vascular Remodeling	2019
Genetic disruption of guanylyl cyclase/natriuretic peptide receptor-A upregulates renal (pro) renin receptor expression in Npr1 null mutant mice. Peptides, 2019, Volume: 114 Topics: Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Captopril; Cyclic GMP; Female; Kidney; Losartan; Male; Mice, Inbred C57BL; Mice, Knockout; Mice, Mutant Strains; Mitogen-Activated Protein Kinases; Peptidyl-Dipeptidase A; Prorenin Receptor; Receptor, Angiotensin, Type 1; Receptors, Atrial Natriuretic Factor; Receptors, Cell Surface	2019
Blood pressure lowering effect of Ficus deltoidea var kunstleri in spontaneously hypertensive rats: possible involvement of renin-angiotensin-aldosterone system, endothelial function and anti-oxidant system. Molecular biology reports, 2019, Volume: 46, Issue:3 Topics: Angiotensin II; Animals; Antioxidants; Blood Pressure; Captopril; Disease Models, Animal; Drugs, Chinese Herbal; Ficus; Hypertension; Losartan; Male; Nitric Oxide Synthase Type III; Peptidyl-Dipeptidase A; Plant Extracts; Rats; Rats, Inbred SHR; Renin-Angiotensin System	2019
A Comparative Study on the Memory-Enhancing Actions of Oral Renin-Angiotensin System Altering Drugs in Scopolamine-Treated Mice. American journal of Alzheimer's disease and other dementias, 2019, Volume: 34, Issue:5 Topics: Administration, Oral; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Humans; Losartan; Male; Maze Learning; Memory Disorders; Memory, Long-Term; Memory, Short-Term; Mice; Muscarinic Antagonists; Ramipril; Renin-Angiotensin System; Scopolamine; Spatial Memory	2019
Angiotensin Type 1 Receptors and Superoxide Anion Production in Hypothalamic Paraventricular Nucleus Contribute to Capsaicin-Induced Excitatory Renal Reflex and Sympathetic Activation. Neuroscience bulletin, 2020, Volume: 36, Issue:5 Topics: 6-Cyano-7-nitroquinoxaline-2,3-dione; Acetophenones; Acetylcysteine; Allopurinol; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Capsaicin; Captopril; Ditiocarb; Kidney; Losartan; Male; NADPH Oxidases; Onium Compounds; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reflex; Superoxides	2020
Reduction of Liver Metastasis Stiffness Improves Response to Bevacizumab in Metastatic Colorectal Cancer. Cancer cell, 2020, 06-08, Volume: 37, Issue:6 Topics: Angiogenesis Inhibitors; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Bevacizumab; Cancer-Associated Fibroblasts; Captopril; Colorectal Neoplasms; Drug Synergism; Humans; Liver Neoplasms; Losartan; Lung Neoplasms; Neovascularization, Pathologic; Renin-Angiotensin System; Tumor Microenvironment	2020
N-Acetyl-Seryl-Asparyl-Lysyl-Proline regulates lung renin angiotensin system to inhibit epithelial-mesenchymal transition in silicotic mice. Toxicology and applied pharmacology, 2020, 12-01, Volume: 408 Topics: Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Cell Line; Epithelial-Mesenchymal Transition; Fibrosis; Losartan; Lung; Male; Mice, Inbred C57BL; Oligopeptides; Peptide Fragments; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Silicosis	2020
Interference with the renin-angiotensin system reduces the palatability of 0.3 M NaCl in sodium-deplete rats. Appetite, 2021, 03-01, Volume: 158 Topics: Animals; Appetite; Captopril; Losartan; Rats; Renin-Angiotensin System; Sodium; Sodium Chloride	2021
Soluble (pro)renin receptor induces endothelial dysfunction and hypertension in mice with diet-induced obesity via activation of angiotensin II type 1 receptor. Clinical science (London, England : 1979), 2021, 03-26, Volume: 135, Issue:6 Topics: Animals; Antihypertensive Agents; Blood Pressure; Captopril; Diet, High-Fat; Human Umbilical Vein Endothelial Cells; Humans; Hydrogen Peroxide; Hypertension; Losartan; Male; Mice; Mice, Inbred C57BL; Obesity; Prorenin Receptor; Receptor, Angiotensin, Type 1; Receptors, Cell Surface; Renin-Angiotensin System	2021
Sodium palatability in male spontaneously hypertensive rats. Hormones and behavior, 2021, Volume: 130 Topics: Animals; Captopril; Furosemide; Losartan; Male; Rats; Rats, Inbred SHR; Sodium	2021
Evaluation of the Effect of Captopril and Losartan on Tacrolimus-induced Nephrotoxicity in Rats. Drug research, 2021, Volume: 71, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme 2; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Urea Nitrogen; Captopril; Creatinine; Epithelium; Kidney Diseases; Kidney Tubules, Proximal; Losartan; Male; Peptidyl-Dipeptidase A; Rats; Renin-Angiotensin System; Tacrolimus	2021
Renoprotective Effects of Small Interfering RNA Targeting Liver Angiotensinogen in Experimental Chronic Kidney Disease. Hypertension (Dallas, Tex. : 1979), 2021, 05-05, Volume: 77, Issue:5 Topics: Angiotensin II; Angiotensinogen; Animals; Antihypertensive Agents; Arterial Pressure; Captopril; Disease Models, Animal; Kidney; Liver; Losartan; Rats; Renal Insufficiency, Chronic; Renin-Angiotensin System; RNA, Small Interfering	2021
Comparison of the effects of losartan, captopril, angiotensin II type 2 receptor agonist compound 21, and MAS receptor agonist AVE 0991 on myocardial ischemia-reperfusion necrosis in rats. Fundamental & clinical pharmacology, 2021, Volume: 35, Issue:4 Topics: Animals; Captopril; Imidazoles; Losartan; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Receptor, Angiotensin, Type 2; Sulfonamides; Thiophenes	2021
Effects of Captopril and Losartan on Cardiac Stereology in Rats with Renovascular Hypertension. Iranian journal of medical sciences, 2021, Volume: 46, Issue:3 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Captopril; Disease Models, Animal; Heart; Hypertension, Renovascular; Iran; Losartan; Male; Rats; Rats, Sprague-Dawley	2021
Captopril and losartan attenuate behavioural sensitization in mice chronically exposed to toluene. Behavioural brain research, 2022, 02-10, Volume: 418 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Behavior, Addictive; Blood Pressure; Captopril; Inhalation; Losartan; Male; Mice; Renin-Angiotensin System; Toluene	2022
Angiotensinergic neurotransmission in the bed nucleus of the stria terminalis is involved in cardiovascular responses to acute restraint stress in rats. Pflugers Archiv : European journal of physiology, 2023, Volume: 475, Issue:4 Topics: Animals; Captopril; Heart Rate; Losartan; Rats; Rats, Wistar; Septal Nuclei; Synaptic Transmission	2023
COVID-19: Understanding the impact of anti-hypertensive drugs and hydroxychloroquine on the ACE1 and ACE2 in lung and adipose tissue in SHR and WKY rats. Physiological reports, 2023, Volume: 11, Issue:3 Topics: Adipose Tissue; Angiotensin-Converting Enzyme 2; Animals; Antihypertensive Agents; Blood Pressure; Captopril; COVID-19; COVID-19 Drug Treatment; Female; Humans; Hydroxychloroquine; Hypertension; Losartan; Lung; Male; Peptidyl-Dipeptidase A; Rats; Rats, Inbred SHR; Rats, Inbred WKY; SARS-CoV-2	2023
Expression of Trpa1 and Trpv1 Genes in the Hypothalamus and Blood Pressure in Normotensive and Hypertensive Rats. Effect of Losartan and Captopril. Bulletin of experimental biology and medicine, 2023, Volume: 174, Issue:4 Topics: Angiotensin II; Animals; Blood Pressure; Captopril; Hypertension; Hypothalamus; Losartan; Rats; TRPA1 Cation Channel; TRPV Cation Channels	2023