losartan and bradykinin

losartan has been researched along with bradykinin in 113 studies

Research

Studies (113)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	66 (58.41)	18.2507
2000's	42 (37.17)	29.6817
2010's	5 (4.42)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Altieri, P; De Mello, W	1
Carretero, OA; Farhy, RD; Ho, KL; Scicli, AG	2
Clozel, JP; Fischli, W; Hess, P; Véniant, M	1
Carretero, O; Fenoy, FJ; Roman, RJ; Scicli, G	1
Hajj-ali, AF; Zimmerman, BG	1
Carini, DJ; Chiu, AT; Duncia, JV; Johnson, AL; Price, WA; Timmermans, PB; Wexler, RR; Wong, PC	1
Campbell, DJ; Kladis, A; Valentijn, AJ	1
Chen, C; Lokhandwala, MF	1
Cockcroft, JR; Goldberg, MR; Ritter, JM; Sciberras, DG	2
Arnet, U; Lüscher, TF; Siebenmann, R; Turina, M; von Segesser, L; Yang, Z	1
Hartman, JC	1
Vane, J	1
Adamiak, D; Kregel, KC; Mott, A; Redlich, T; Stauss, HM; Unger, T; Zhu, YC	1
Cachofeiro, V; Lahera, V; Maeso, R; Navarro, J; Rodrigo, E; Ruilope, LM	1
Broten, TP; Chakravarty, PK; Gabel, RA; Greenlee, WJ; Kivlighn, SD; Naylor, EM; Patchett, AA; Schaffer, LW; Schorn, TW; Zingaro, GJ	1
Fujishima, K; Hachisu, M; Hui, C; Katano, K; Kawano, K; Konno, F; Nagura, J; Ogino, H; Yamamoto, M; Yasuda, S	1
Feng, CJ; Kadowitz, PJ; Kaye, AD; Nossaman, BD	1
Chen, C; Lokhandwala, MF; Sakamoto, T	1
Janiak, P; Libert, O; Vilaine, JP	1
Chen, K; Zimmerman, BG	1
Abeta, H; Asagami, T; Furukawa, L; Hino, T; Ishii, T; Kushiro, T; Otsuka, Y; Saito, F; Takahashi, A; Tomiyama, H	1
Castillo, G; Esteban, S; Orce, G	1
da Silva, SV; da Silva, VJ; Salgado, HC; Salgado, MC	1
Hjemdahl, P; Kahan, T; Nussberger, J; Schwieler, JH	1
Awan, NA; Mason, DT	1
Bergelson, BA; Gavras, H; Gavras, I; Ruocco, NA; Yu, TK	1
Chauvin, B; Giudicelli, JF; Richer, C	1
Elghozi, JL; Ponchon, P	2
Hérizi, A; Jover, B; Mimran, A	1
Duan, J; Fernandes, BH; Jaramillo, J; Jung, GL; Mathis, D; McLeod, AL	1
Deck, CC; Gaballa, MA; Raya, TE	1
de Champlain, J; Foucart, S; Oster, L; Patrick, SK	1
Carey, RM; Jaffa, AA; Margolius, HS; Siragy, HM	1
Cachofeiro, V; Casal, MC; Lahera, V; Maeso, R; Munoz-Garcia, R; Navarro, J; Rodrigo, E; Ruilope, LM	1
Amann, K; Gohlke, P; Kuwer, I; Mall, G; Schnell, A; Unger, T	1
Higson, JT; Tallant, EA	1
Fregly, MJ; Rowland, NE	1
Bolla, BS; de Guzman, FQ; Hussain, Y; Igić, R; Montiague, RR; Rabito, SF; Rajani, V	1
Berkenboom, G; Carpentier, Y; Fontaine, J; Grosfils, K; Langer, I	1
Adam, A; Blais, C; Drapeau, G; Gervais, N; Lamontagne, D; Raymond, P; Venneman, I	1
Carvalho, CR; Gontijo, JA; Saad, MJ; Thirone, AC; Velloso, LA	1
Gohlke, P; Pees, C; Unger, T	1
Chappell, MC; Ferrario, CM; Iyer, SN	1
Heller, J; Horácek, V; Kramer, HJ	1
Arnal, JF; Michel, JB; Pueyo, ME; Rami, J	1
Boon, NA; Johnston, NR; Masumori, S; Newby, DE; Webb, DJ	1
Bischoff, A; Michel, MC; Rascher, W	1
Struthers, AD	1
Brown, NJ; Gainer, JV; King, DJ; Loveland, A; Morrow, JD	1
Demeilliers, B; Jover, B; Mimran, A	1
Anders, HJ; Ertl, G; Gaudron, P; Hu, K; Nahrendorf, M; Turschner, O; Weidemann, F	1
Angus, JA; Whorlow, SL; Wright, CE	1
Block, ER; Hill-Kapturczak, N; Kapturczak, MH; Madsen, KM; Malinski, T; Patel, JM; Tisher, CC	1
Azizi, M	1
Allegrini, PR; Buser, PT; Hornstein, PS; Zaugg, CE; Zhu, P	1
Carey, RM; Siragy, HM	1
Dargie, HJ; Davie, AP; McMurray, JJ	1
Daihara, M; Kawahara, K; Nakagawa, H; Nozue, T; Tamakawa, H	1
Blair-West, JR; Harris, PJ; Rajaratne, AA; Walker, LL	1
Dukacz, SA; Kline, RL	1
Baldassarre, S; Berkenboom, G; Fontaine, D; Fontaine, J; Preumont, N; Unger, P	1
Altun, B; Arici, M; Cağlar, S; Erdem, Y; Haznedaroğlu, IC; Turgan, C; Usalan, C; Yasavul, U	1
Kojima, S; Kuramochi, M; Saotome, M; Shida, M; Tanaka, K; Yoshitomi, Y	1
Gutierez, CI; Israel, A; Sosa, B	1
Eichler, HG; Frossard, M; Joukhadar, C; Müller, M; Schmid, R; Steffen, G	1
Bischoff, A; Michel, MC	1
Cierco, M; Israel, A; Sosa, B	1
Francisco-DoPrado, J; Gordo, WM; Moreno, H; Sampaio, RC; Tanus-Santos, JE	1
Cierco, M; Gutierrez, CI; Israel, A; Sosa-Canache, B	1
Bergström, G; Creutz, J; Göthberg, G; Karlström, G; Rudenstam, J	1
Boegehold, MA; Nurkiewicz, TR	1
Vaughan, D	1
Das, DK; Deaton, DW; Engelman, RM; Flack, JE; Maulik, N; Otani, H; Rousou, JA; Sato, M	1
Calegari, V; do Prado, JF; Moreno, H; Paganelli, MO; Tanus-Santos, JE; Toledo, JC	1
Fowler, MB; Jamali, AH; Khot, UN; Tang, WH	1
Connell, JM; Hillier, C; McDonald, JE; McMurray, JJ; Padmanabhan, N; Petrie, MC	1
Hauser, AC; Hörl, WH	1
Fabiani, ME; Frauman, AG; Johnston, CI; Sourial, M; Thomas, WG	1
Inami, S; Kojima, S; Kuramochi, M; Shida, M; Takano, H; Yodogawa, K; Yokoyama, H	1
Boon, NA; Johnston, NR; Labinjoh, C; Newby, DE; Pellegrini, MP; Webb, DJ	1
Dell'Italia, LJ; Lucchesi, PA; Rocic, P	1
Campbell, DJ; Mackie, FE; Meyer, TW	1
Patel, KP; Wang, W; Zhu, GQ; Zucker, IH	1
Doverspike, A; Hentosz, T; Huerbin, R; Nikolaidis, LA; Shannon, RP	1
Wang, W; Zhu, GQ; Zucker, IH	1
Fukuyama, R; Fushiki, S; Harada, S; Hatta, T; Kido, H; Nakata, T; Oguni, A; Sasaki, S; Takeda, K	1
Giacca, A; Lapointe, N; Leung, N; Lewis, GF; Rouleau, JL; Szeto, L; Uffelman, KD; Wang, CH	1
Horie, H; Horie, M; Kinoshita, M; Matsumoto, T; Matsuo, S; Minai, K; Ohira, N; Ozawa, T; Takashima, H; Tarutani, Y; Yasuda, Y	1
Epelde, F; Heras, M; Pérez-Villa, F; Rigol, M; Roig, E; Roqué, M; Sanz, G; Solanes, N	1
Hintze, TH; Huang, H; Kaley, G; Kaminski, PM; Kinugawa, S; Ochoa, M; Post, H; Recchia, FA; Wolin, MS; Xu, X; Zhang, X	1
Cruden, NL; Fox, KA; Newby, DE; Webb, DJ; Witherow, FN	1
Hiyoshi, H; Okamoto, H; Takano, M; Yayama, K	1
Alhenc-Gelas, F; Bergaya, S; Bloch-Faure, M; Boulanger, CM; Dong, Y; Hilgers, RH; Inagami, T; Lévy, BI; Meneton, P	1
Adler, S; Huang, H	1
Campbell, DJ; Esler, MD; Krum, H	1
Berti, F; Bianchi, M; Bonomo, S; De Gennaro Colonna, V; Ferrario, P; Fioretti, S; Manfredi, B; Muller, EE; Rigamonti, A; Rossoni, G	1
Aihara, E; Hayashi, M; Kagawa, S; Takeuchi, K	1
Berti, F; Bonomo, S; De Gennaro Colonna, V; Fioretti, S; Manfredi, B; Muller, EE; Rigamonti, A; Rossoni, G	1
Erhardt, LR; Höglund, P; Jönsson, BA; Juhlin, T; Ottosson, H	1
Arndt, PG; Falk, S; Nick, JA; Poch, KR; Schrier, RW; Worthen, GS; Young, SK	1
Akimitsu, T; Akiyoshi, K; Hara, M; Saikawa, T; Yoshimatsu, H	1
Miyagi, R; Okamoto, H; Sugiyama, K; Yayama, K	1
Bos, AP; Florquin, S; Haitsma, JJ; Lachmann, B; Lutter, R; Merkus, MP; van der Loos, CM; van Woensel, JB; Wösten-van Asperen, RM	1
Akira, T; Egi, Y; Maruyama, T; Matsumura, Y; Ohkita, M; Sasaoka, T; Takaoka, M; Tawa, M; Yamamoto, A	1
Costa, CA; Criddle, DN; Espinoza, LA; Marins de Carvalho, LC; Ognibene, DT; Oliveira, PR; Resende, AC; Soares de Moura, R; Tano, T	1
Bonde, MM; Erikstrup, N; Hansen, JL; Haunsø, S; Lyngsø, C; Nielsen, MS; Olsen, KB; Sheikh, SP; Speerschneider, T	1
Arias-Santiago, S; Husein-Elahmed, H; Orgaz-Molina, J; Soriano-Hernández, MI	1
Fan, ZD; Gan, XB; Gao, XY; Xiong, XQ; Zhang, L; Zhu, GQ	1
Addabbo, F; Carratù, MR; Iacobazzi, D; Leo, V; Montagnani, M; Potenza, MA; Sgarra, L	1
Augusto, MJ; Elias Júnior, J; Parreira, NA; Prado, CM; Ramalho, FS; Ramalho, LNZ; Rodrigues, V; Silva, DM	1

Reviews

4 review(s) available for losartan and bradykinin

Article	Year
Direct selective blockade of the vascular angiotensin II receptors in therapy for hypertension and severe congestive heart failure. American heart journal, 1996, Volume: 131, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bradykinin; Heart Failure; Humans; Hypertension; Imidazoles; Losartan; Prostaglandin Antagonists; Receptors, Angiotensin; Tetrazoles	1996
Pharmacology of ACE inhibitors versus AT1 blockers. The Canadian journal of cardiology, 2000, Volume: 16 Suppl E Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Arteriosclerosis; Blood Pressure; Bradykinin; Endothelium, Vascular; Fibrinolysis; Humans; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Renin-Angiotensin System; Vasodilation	2000
The role of angiotensin receptor blockers in the management of chronic heart failure. Archives of internal medicine, 2001, Mar-12, Volume: 161, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Chronic Disease; Clinical Trials as Topic; Forecasting; Heart Failure; Humans; Losartan	2001
[Angiotensin II type-1-receptor antagonists from the viewpoint of nephrology]. Wiener medizinische Wochenschrift (1946), 2001, Volume: 151, Issue:7-8 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Diabetic Nephropathies; Dose-Response Relationship, Drug; Glomerular Filtration Rate; Humans; Hypertension; Kidney; Losartan; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Therapeutic Equivalency	2001

Trials

11 trial(s) available for losartan and bradykinin

Article	Year
Comparison of angiotensin-converting enzyme inhibition with angiotensin II receptor antagonism in the human forearm. Journal of cardiovascular pharmacology, 1993, Volume: 22, Issue:4 Topics: Adult; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Bradykinin; Double-Blind Method; Drug Interactions; Enalapril; Forearm; Heart Rate; Humans; Imidazoles; Losartan; Male; Regional Blood Flow; Tetrazoles; Vascular Resistance; Vasoconstriction; Vasodilation	1993
Clinical pharmacology of angiotensin and bradykinin in human forearm vasculature. Journal of hypertension. Supplement : official journal of the International Society of Hypertension, 1993, Volume: 11, Issue:3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Vessels; Bradykinin; Enalapril; Forearm; Humans; Imidazoles; Losartan; Peptidyl-Dipeptidase A; Renin-Angiotensin System; Tetrazoles	1993
Endogenous angiotensin II contributes to basal peripheral vascular tone in sodium deplete but not sodium replete man. Cardiovascular research, 1997, Volume: 36, Issue:2 Topics: Adult; Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Vessels; Bradykinin; Diuretics; Dose-Response Relationship, Drug; Forearm; Furosemide; Humans; Losartan; Lower Body Negative Pressure; Male; Norepinephrine; Regional Blood Flow; Sodium; Sodium, Dietary; Vasoconstriction; Vasoconstrictor Agents	1997
Effect of bradykinin-receptor blockade on the response to angiotensin-converting-enzyme inhibitor in normotensive and hypertensive subjects. The New England journal of medicine, 1998, Oct-29, Volume: 339, Issue:18 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Diet, Sodium-Restricted; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypertension; Kidney; Losartan; Male; Reference Values; Renin-Angiotensin System; Single-Blind Method	1998
Role of bradykinin in the vasodilator effects of losartan and enalapril in patients with heart failure. Circulation, 1999, Jul-20, Volume: 100, Issue:3 Topics: Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Cross-Over Studies; Double-Blind Method; Drug Interactions; Enalapril; Female; Heart Failure; Humans; Losartan; Male; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Vasodilator Agents	1999
Effects of angiotensin converting enzyme and angiotensin II receptor inhibition on impaired fibrinolysis in systemic hypertension. American journal of hypertension, 1999, Volume: 12, Issue:11 Pt 1 Topics: Adolescent; Adult; Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Female; Fibrinolysis; Fibrinolytic Agents; Humans; Hypertension; Lipoproteins; Losartan; Male; Middle Aged; Perindopril; Plasminogen Activator Inhibitor 1; Thrombomodulin; Tissue Plasminogen Activator	1999
Potentiation of bradykinin-induced tissue plasminogen activator release by angiotensin-converting enzyme inhibition. Journal of the American College of Cardiology, 2001, Nov-01, Volume: 38, Issue:5 Topics: Adult; Analysis of Variance; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Brachial Artery; Bradykinin; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Synergism; Endothelium, Vascular; Fibrinolysis; Forearm; Humans; Infusions, Intravenous; Isoquinolines; Losartan; Male; Nitroprusside; Plethysmography, Impedance; Quinapril; Substance P; Tetrahydroisoquinolines; Tissue Plasminogen Activator; Vasodilator Agents	2001
Angiotensin-converting enzyme inhibition but not angiotensin II type 1 receptor antagonism augments coronary release of tissue plasminogen activator in hypertensive patients. Journal of the American College of Cardiology, 2003, Apr-16, Volume: 41, Issue:8 Topics: Aged; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bradykinin; Coronary Circulation; Dose-Response Relationship, Drug; Female; Fibrinolysis; Humans; Hypertension; Losartan; Male; Middle Aged; Perindopril; Receptor, Angiotensin, Type 1; Tissue Plasminogen Activator	2003
Bradykinin contributes to the systemic hemodynamic effects of chronic angiotensin-converting enzyme inhibition in patients with heart failure. Arteriosclerosis, thrombosis, and vascular biology, 2004, Volume: 24, Issue:6 Topics: Aged; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cardiac Output; Cross-Over Studies; Double-Blind Method; Enalapril; Female; Forearm; Heart Failure; Heart Rate; Hemodynamics; Humans; Losartan; Male; Middle Aged; Peptidyl-Dipeptidase A; Regional Blood Flow; Vasodilation	2004
Losartan increases bradykinin levels in hypertensive humans. Circulation, 2005, Jan-25, Volume: 111, Issue:3 Topics: Acrylates; Adolescent; Adult; Aged; Angiotensin I; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Bradykinin; Chromatography, High Pressure Liquid; Cross-Over Studies; Double-Blind Method; Female; Humans; Hydroxylation; Hypertension; Imidazoles; Kallidin; Losartan; Male; Middle Aged; Peptide Fragments; Radioimmunoassay; Thiophenes	2005
Treatments with losartan or enalapril are equally sensitive to deterioration in renal function from cyclooxygenase inhibition. European journal of heart failure, 2007, Volume: 9, Issue:2 Topics: Aged; Aged, 80 and over; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Bradykinin; Cyclooxygenase 2 Inhibitors; Diclofenac; Diuretics; Enalapril; Female; Glomerular Filtration Rate; Heart Failure; Humans; Kidney; Losartan; Male; Middle Aged; Renin-Angiotensin System; Time Factors	2007

Other Studies

98 other study(ies) available for losartan and bradykinin

Article	Year
The role of the renin-angiotensin system in the control of cell communication in the heart: effects of enalapril and angiotensin II. Journal of cardiovascular pharmacology, 1992, Volume: 20, Issue:4 Topics: Angiotensin II; Animals; Biphenyl Compounds; Bradykinin; Cell Communication; Enalapril; Heart; Imidazoles; In Vitro Techniques; Losartan; Membrane Potentials; Protein Kinase C; Protein Kinases; Rats; Renin-Angiotensin System; Tetrazoles	1992
Kinins mediate the antiproliferative effect of ramipril in rat carotid artery. Biochemical and biophysical research communications, 1992, Jan-15, Volume: 182, Issue:1 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Bridged Bicyclo Compounds; Carotid Arteries; Carotid Artery Injuries; Endothelium, Vascular; Imidazoles; Kinins; Losartan; Male; Muscle, Smooth, Vascular; Oligopeptides; Ramipril; Rats; Rats, Inbred Strains; Tetrazoles	1992
Effects of renin-angiotensin system blockade in guinea pigs. Hypertension (Dallas, Tex. : 1979), 1992, Volume: 19, Issue:3 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Cilazapril; Cyclooxygenase Inhibitors; Disease Models, Animal; Furosemide; Guinea Pigs; Hypertension; Imidazoles; Indomethacin; Losartan; Nephrectomy; Oligopeptides; Pyridazines; Renin; Renin-Angiotensin System; Tetrazoles	1992
Effect of an angiotensin II and a kinin receptor antagonist on the renal hemodynamic response to captopril. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:6 Pt 2 Topics: Angiotensin II; Animals; Bradykinin; Captopril; Hemodynamics; Imidazoles; Kinins; Lasers; Losartan; Punctures; Rats; Rats, Inbred Strains; Receptors, Bradykinin; Receptors, Neurotransmitter; Renal Circulation; Tetrazoles; Ultrasonography	1991
Kinin contribution to renal vasodilator effect of captopril in rabbit. Hypertension (Dallas, Tex. : 1979), 1991, Volume: 17, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bradykinin; Captopril; Imidazoles; Kidney; Losartan; Rabbits; Receptors, Bradykinin; Receptors, Neurotransmitter; Renal Circulation; Saralasin; Tetrazoles; Vasodilation	1991
Nonpeptide angiotensin II receptor antagonists. VIII. Characterization of functional antagonism displayed by DuP 753, an orally active antihypertensive agent. The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:2 Topics: Administration, Oral; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Azoles; Blood Pressure; Bradykinin; Imidazoles; Losartan; Male; Rats; Rats, Inbred Strains; Receptors, Angiotensin; Renin; Renin-Angiotensin System; Tetrazoles	1990
Effects of losartan on angiotensin and bradykinin peptides and angiotensin-converting enzyme. Journal of cardiovascular pharmacology, 1995, Volume: 26, Issue:2 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Bradykinin; Imidazoles; Losartan; Male; Organ Specificity; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Tetrazoles	1995
Potentiation by enalaprilat of fenoldopam-evoked natriuresis is due to blockade of intrarenal production of angiotensin-II in rats. Naunyn-Schmiedeberg's archives of pharmacology, 1995, Volume: 352, Issue:2 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Diuresis; Dopamine Agonists; Drug Synergism; Enalaprilat; Fenoldopam; Glomerular Filtration Rate; Imidazoles; Kidney; Losartan; Male; Natriuresis; Rats; Rats, Sprague-Dawley; Tetrazoles	1995
Different effects of angiotensin-converting enzyme inhibition in human arteries and veins. Journal of cardiovascular pharmacology, 1993, Volume: 22 Suppl 5 Topics: Acetylcholine; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Bradykinin; Enalaprilat; Endothelium, Vascular; Humans; Imidazoles; In Vitro Techniques; Losartan; Mammary Arteries; Muscle Contraction; Muscle Relaxation; Muscle, Smooth, Vascular; Norepinephrine; Saphenous Vein; Tetrazoles	1993
The role of bradykinin and nitric oxide in the cardioprotective action of ACE inhibitors. The Annals of thoracic surgery, 1995, Volume: 60, Issue:3 Topics: Adrenergic beta-Antagonists; Amino Acid Oxidoreductases; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Heart; Imidazoles; Losartan; Myocardial Infarction; Myocardial Ischemia; Myocardial Reperfusion; Myocardial Reperfusion Injury; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rabbits; Ramipril; Receptors, Angiotensin; Receptors, Bradykinin; Tetrazoles	1995
Trumping the ACE. Lancet (London, England), 1995, Sep-30, Volume: 346, Issue:8979 Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Bradykinin; Drug Synergism; Humans; Imidazoles; Losartan; Tetrazoles	1995
Angiotensin-converting enzyme inhibition in infarct-induced heart failure in rats: bradykinin versus angiotensin II. Journal of cardiovascular risk, 1994, Volume: 1, Issue:3 Topics: Adrenergic beta-Antagonists; Analysis of Variance; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Disease Models, Animal; Heart; Heart Failure; Hemodynamics; Imidazoles; Isoquinolines; Losartan; Male; Myocardial Contraction; Myocardial Infarction; Myocardium; Organ Size; Rats; Rats, Wistar; Tetrahydroisoquinolines; Tetrazoles	1994
Nitric oxide and prostaglandins in the prolonged effects of losartan and ramipril in hypertension. Hypertension (Dallas, Tex. : 1979), 1995, Volume: 26, Issue:2 Topics: Animals; Antihypertensive Agents; Arginine; Biphenyl Compounds; Blood Pressure; Bradykinin; Drug Interactions; Hypertension; Imidazoles; Indomethacin; Kidney Function Tests; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Ramipril; Rats; Rats, Inbred SHR; Tetrazoles	1995
Role of kinins and nitric oxide in the effects of angiotensin converting enzyme inhibitors on neointima formation. Circulation research, 1993, Volume: 72, Issue:6 Topics: Amino Acid Oxidoreductases; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biphenyl Compounds; Bradykinin; Carotid Arteries; Imidazoles; Kinins; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Receptors, Bradykinin; Receptors, Neurotransmitter; Tetrazoles; Tunica Intima	1993
In vivo pharmacology of a novel AT1 selective angiotensin II receptor antagonist, MK-996. American journal of hypertension, 1995, Volume: 8, Issue:1 Topics: Administration, Oral; Aldosterone; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Bradykinin; Dogs; Enalapril; Female; Imidazoles; Injections, Intravenous; Losartan; Macaca mulatta; Male; Nitroglycerin; Pan troglodytes; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles	1995
Pharmacological profile of ME3221, a novel angiotensin II receptor antagonist. European journal of pharmacology, 1995, Feb-14, Volume: 274, Issue:1-3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta, Thoracic; Biphenyl Compounds; Blood Pressure; Bradykinin; Callithrix; Disease Models, Animal; Drug Evaluation; Female; Femoral Artery; Heart Rate; Hypertension, Renal; Imidazoles; Losartan; Male; Rabbits; Rats; Rats, Inbred SHR; Rats, Sprague-Dawley; Species Specificity; Tetrazoles	1995
Analysis of responses to ANG IV: effects of PD-123319 and DuP-753 in the pulmonary circulation of the rat. The American journal of physiology, 1995, Volume: 268, Issue:2 Pt 1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Hypoxia; Imidazoles; Losartan; Male; Meclofenamic Acid; Nitric Oxide; Pulmonary Artery; Pulmonary Circulation; Pyridines; Rats; Rats, Sprague-Dawley; Tetrazoles; Vasoconstriction	1995
Contribution by bradykinin to the natriuretic response to the angiotensin converting enzyme inhibitor ramiprilat in spontaneously hypertensive rats. Naunyn-Schmiedeberg's archives of pharmacology, 1994, Volume: 350, Issue:1 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Glomerular Filtration Rate; Hemodynamics; Imidazoles; Losartan; Male; Natriuresis; Ramipril; Rats; Rats, Inbred SHR; Sodium; Tetrazoles	1994
Role of the renin-angiotensin system in neointima formation after injury in rabbits. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 24, Issue:6 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Heart Rate; Imidazoles; Indoles; Losartan; Male; Oligopeptides; Perindopril; Rabbits; Receptors, Angiotensin; Renin-Angiotensin System; Tetrazoles; Tunica Intima; Wound Healing	1994
Comparison of renal hemodynamic effect of ramiprilat to captopril; possible role of kinins. The Journal of pharmacology and experimental therapeutics, 1994, Volume: 270, Issue:2 Topics: Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Imidazoles; Kidney; Kinins; Losartan; Male; Rabbits; Ramipril; Renal Circulation; Tetrazoles	1994
Kinins contribute to the improvement of insulin sensitivity during treatment with angiotensin converting enzyme inhibitor. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:4 Topics: Analysis of Variance; Angiotensin II; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Glucose; Blood Pressure; Body Weight; Bradykinin; Doxazosin; Enalapril; Glucose Clamp Technique; Hypertension; Imidazoles; Insulin; Kinins; Losartan; Male; Potassium; Rats; Rats, Inbred SHR; Sodium; Tetrazoles	1994
Oxytocic effect of trypsin on the isolated rat uterus. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:1 Suppl Topics: Angiotensin I; Angiotensin II; Animals; Biphenyl Compounds; Bradykinin; Dose-Response Relationship, Drug; Enalaprilat; Female; Imidazoles; In Vitro Techniques; Isometric Contraction; Losartan; Oxytocin; Pepstatins; Rats; Saralasin; Tetrazoles; Trypsin; Uterine Contraction; Uterus	1994
Chronic converting enzyme inhibition facilitates baroreceptor resetting to hypertensive levels. Hypertension (Dallas, Tex. : 1979), 1994, Volume: 23, Issue:1 Suppl Topics: Angiotensin I; Angiotensin II; Animals; Aorta; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Enalapril; Hypertension; Imidazoles; Losartan; Male; Pressoreceptors; Rats; Rats, Wistar; Reference Values; Regression Analysis; Tetrazoles	1994
Converting enzyme inhibition modulates sympathetic neurotransmission in vivo via multiple mechanisms. The American journal of physiology, 1993, Volume: 264, Issue:4 Pt 1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzazepines; Biphenyl Compounds; Blood Pressure; Bradykinin; Diclofenac; Dogs; Epinephrine; Female; Imidazoles; Losartan; Muscle Denervation; Muscles; Norepinephrine; Phenoxybenzamine; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles	1993
Augmentation of coronary blood flow by ACE inhibition: role of angiotensin and bradykinin. Clinical and experimental hypertension (New York, N.Y. : 1993), 1995, Volume: 17, Issue:7 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Flow Velocity; Blood Pressure; Bradykinin; Captopril; Coronary Vessels; Imidazoles; Losartan; Perfusion; Swine; Tetrazoles	1995
Lack of involvement of bradykinin in the vascular sympathoinhibitory effects of angiotensin converting enzyme inhibitors in spontaneously hypertensive rats. British journal of pharmacology, 1995, Volume: 116, Issue:4 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Decerebrate State; Hemodynamics; Hypertension; Imidazoles; Indoles; Losartan; Male; Muscle, Smooth, Vascular; Perindopril; Rats; Rats, Inbred SHR; Sympathetic Nervous System; Synaptic Transmission; Tetrazoles; Vasoconstriction	1995
[Hormonal contribution to short-term variability of blood pressure in a renovascular hypertension model]. Archives des maladies du coeur et des vaisseaux, 1995, Volume: 88, Issue:8 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bradykinin; Disease Models, Animal; Heart Rate; Hypertension, Renovascular; Imidazoles; Kallikrein-Kinin System; Losartan; Male; Rats; Receptors, Angiotensin; Renin-Angiotensin System; Signal Processing, Computer-Assisted; Tetrazoles	1995
Chronic kinin blockade and effect of ramipril in renal adaptation to sodium restriction. Hypertension (Dallas, Tex. : 1979), 1996, Volume: 27, Issue:1 Topics: Adaptation, Physiological; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Diet, Sodium-Restricted; Electrolytes; Hemodynamics; Imidazoles; Kidney; Losartan; Male; Ramipril; Rats; Rats, Sprague-Dawley; Renal Circulation; Renin-Angiotensin System; Tetrazoles; Time Factors	1996
Comparative studies on differential inhibition of the renin - angiotensin system in the anesthetized guinea pig. Canadian journal of physiology and pharmacology, 1995, Volume: 73, Issue:10 Topics: Alanine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Blood Pressure; Bradykinin; Captopril; Guinea Pigs; Imidazoles; Losartan; Male; Nephrectomy; Pyridines; Renin; Renin-Angiotensin System; Tetrazoles; Thiazoles	1995
Relative contribution of angiotensin II, bradykinin, and prostaglandins to the renal effects of converting enzyme inhibition in rats after chronic myocardial infarction. Journal of cardiovascular pharmacology, 1996, Volume: 28, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Cyclooxygenase Inhibitors; Hemodynamics; Imidazoles; Indomethacin; Kidney; Kidney Function Tests; Losartan; Male; Myocardial Infarction; Rats; Rats, Sprague-Dawley; Tetrazoles	1996
Effects of chronic treatment with losartan and enalaprilat on [3H]-norepinephrine release from isolated atria of Wistar-Kyoto and spontaneously hypertensive rats. American journal of hypertension, 1996, Volume: 9, Issue:1 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Body Weight; Bradykinin; Enalaprilat; Heart Atria; Imidazoles; Losartan; Norepinephrine; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Renin-Angiotensin System; Tetrazoles	1996
Contribution of the renin-angiotensin and kallikrein-kinin systems to short-term variability of blood pressure in two-kidney, one-clip hypertensive rats. European journal of pharmacology, 1996, Feb-15, Volume: 297, Issue:1-2 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Heart Rate; Hypertension, Renovascular; Imidazoles; Kallikrein-Kinin System; Losartan; Male; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Tetrazoles	1996
Renin-angiotensin system modulates renal bradykinin production. The American journal of physiology, 1996, Volume: 271, Issue:4 Pt 2 Topics: Angiotensin II; Animals; Biphenyl Compounds; Bradykinin; Cyclic GMP; Dinoprostone; Dogs; Drug Combinations; Extracellular Space; Female; Hemodynamics; Imidazoles; Kidney; Losartan; Microdialysis; Oligopeptides; Renal Circulation; Renin-Angiotensin System; Tetrazoles	1996
Acute renal excretory actions of losartan in spontaneously hypertensive rats: role of AT2 receptors, prostaglandins, kinins and nitric oxide. Journal of hypertension, 1995, Volume: 13, Issue:12 Pt 2 Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Biphenyl Compounds; Bradykinin; Enzyme Inhibitors; Hemodynamics; Hypertension; Imidazoles; Infusions, Intravenous; Kidney; Kinins; Losartan; Male; Meclofenamic Acid; Nitric Oxide; omega-N-Methylarginine; Prostaglandins; Pyridines; Rats; Rats, Inbred SHR; Receptors, Angiotensin; Sodium; Tetrazoles	1995
Blockade of bradykinin B2 receptors prevents the increase in capillary density induced by chronic angiotensin-converting enzyme inhibitor treatment in stroke-prone spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 29, Issue:1 Pt 2 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Biphenyl Compounds; Bradykinin; Bradykinin Receptor Antagonists; Capillaries; Coronary Vessels; Hypertension; Hypertrophy, Left Ventricular; Imidazoles; Losartan; Male; Neovascularization, Pathologic; Ramipril; Rats; Rats, Inbred SHR; Receptor, Bradykinin B2; Tetrazoles	1997
Angiotensin II activates distinct signal transduction pathways in astrocytes isolated from neonatal rat brain. Glia, 1997, Volume: 19, Issue:4 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Animals, Newborn; Astrocytes; Biphenyl Compounds; Bradykinin; Brain; Cells, Cultured; Cerebellum; Cerebral Cortex; Epoprostenol; Humans; Hypothalamus; Imidazoles; Losartan; Medulla Oblongata; Peptide Fragments; Phosphatidylinositol Diacylglycerol-Lyase; Pyridines; Rats; Rats, Sprague-Dawley; Signal Transduction; Tetrazoles; Type C Phospholipases	1997
Role of angiotensin in the dipsogenic effect of bradykinin in rats. Pharmacology, biochemistry, and behavior, 1997, Volume: 57, Issue:4 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Angiotensins; Animals; Biphenyl Compounds; Bradykinin; Brain; Captopril; Cerebral Ventricles; Drinking; Imidazoles; Immunohistochemistry; Losartan; Male; Peptidyl-Dipeptidase A; Proto-Oncogene Proteins c-fos; Rats; Rats, Sprague-Dawley; Renin; Tetrazoles; Thirst	1997
Attenuation of epinephrine-induced dysrhythmias by bradykinin: role of nitric oxide and prostaglandins. The American journal of cardiology, 1997, Aug-04, Volume: 80, Issue:3A Topics: Adrenergic beta-Antagonists; Analysis of Variance; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Biphenyl Compounds; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cyclooxygenase Inhibitors; Enzyme Inhibitors; Epinephrine; Heart Rate; Imidazoles; Indomethacin; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Rats; Rats, Sprague-Dawley; Tetrazoles	1997
Ramipril prevents endothelial dysfunction induced by oxidized low-density lipoproteins: a bradykinin-dependent mechanism. Hypertension (Dallas, Tex. : 1979), 1997, Volume: 30, Issue:3 Pt 1 Topics: Acetylcholine; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Endothelium, Vascular; Guanylate Cyclase; Lipoproteins, LDL; Losartan; Male; Nitric Oxide; Ramipril; Rats; Rats, Wistar; Vasodilation	1997
Contribution of angiotensin-converting enzyme to the cardiac metabolism of bradykinin: an interspecies study. The American journal of physiology, 1997, Volume: 273, Issue:5 Topics: Amino Acid Sequence; Angiotensin-Converting Enzyme Inhibitors; Animals; Antibodies; Bradykinin; Cross Reactions; Dogs; Enalaprilat; Humans; Kinetics; Losartan; Myocardium; Peptidyl-Dipeptidase A; Protease Inhibitors; Rabbits; Rats; Species Specificity; Substrate Specificity; Thiorphan	1997
Effect of captopril, losartan, and bradykinin on early steps of insulin action. Diabetes, 1997, Volume: 46, Issue:12 Topics: Aging; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Captopril; Insulin; Insulin Receptor Substrate Proteins; Liver; Losartan; Male; Muscle, Skeletal; Phosphoproteins; Phosphorylation; Rats; Rats, Wistar; Receptor, Insulin	1997
AT2 receptor stimulation increases aortic cyclic GMP in SHRSP by a kinin-dependent mechanism. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2 Topics: Angiotensin II; Animals; Aorta; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cerebrovascular Disorders; Cyclic GMP; Hypertension; Imidazoles; Losartan; Male; Minoxidil; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Reference Values	1998
Angiotensin-(1-7) contributes to the antihypertensive effects of blockade of the renin-angiotensin system. Hypertension (Dallas, Tex. : 1979), 1998, Volume: 31, Issue:1 Pt 2 Topics: Angiotensin I; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Dipeptides; Heart Rate; Hypertension; Kinetics; Lisinopril; Losartan; Male; Neprilysin; Organophosphonates; Peptide Fragments; Peptides, Cyclic; Phenylalanine; Protease Inhibitors; Rats; Rats, Inbred SHR; Renin-Angiotensin System	1998
Comparative effects of the angiotensin II receptor blocker EXP 3174 and of the angiotensin-converting enzyme inhibitor captopril on renal glomerular hemodynamics in the dog. Kidney & blood pressure research, 1997, Volume: 20, Issue:6 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Flow Velocity; Blood Pressure; Bradykinin; Captopril; Dogs; Drug Combinations; Female; Glomerular Filtration Rate; Imidazoles; Kidney Glomerulus; Losartan; Male; Potassium; Sodium; Tetrazoles; Urea; Vascular Resistance; Vasodilation; Water	1997
Angiotensin II stimulates the production of NO and peroxynitrite in endothelial cells. The American journal of physiology, 1998, Volume: 274, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Aorta, Thoracic; Arginine; Bradykinin; Calcium; Calmodulin; Cells, Cultured; Endothelium, Vascular; Losartan; Muscle, Smooth, Vascular; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide; Nitric Oxide Synthase; Oxidants; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sulfonamides	1998
Bradykinin may be involved in neuropeptide Y-induced diuresis, natriuresis, and calciuresis. The American journal of physiology, 1998, Volume: 275, Issue:4 Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Calcium; Creatinine; Denervation; Diuresis; Infusions, Intravenous; Kidney; Losartan; Male; Natriuresis; Neuropeptide Y; Ramipril; Rats; Rats, Wistar; Receptor, Bradykinin B2; Regional Blood Flow; Renal Circulation; Vascular Resistance	1998
Angiotensin II receptor antagonists for heart failure. Heart (British Cardiac Society), 1998, Volume: 80, Issue:1 Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bradykinin; Captopril; Clinical Trials as Topic; Heart Failure; Humans; Losartan; Receptors, Angiotensin	1998
Contrasting renal effects of chronic administrations of enalapril and losartan on one-kidney, one clip hypertensive rats. Journal of hypertension, 1998, Volume: 16, Issue:7 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Diet, Sodium-Restricted; Enalapril; Glomerular Filtration Rate; Hypertension, Renovascular; Kidney; Kinins; Losartan; Male; Rats; Rats, Sprague-Dawley; Renal Circulation; Sodium	1998
Chronic effects of early started angiotensin converting enzyme inhibition and angiotensin AT1-receptor subtype blockade in rats with myocardial infarction: role of bradykinin. Cardiovascular research, 1998, Volume: 39, Issue:2 Topics: Adrenergic beta-Antagonists; Analysis of Variance; Angiotensin I; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Bradykinin Receptor Antagonists; Dose-Response Relationship, Drug; Heart Ventricles; Hemodynamics; Hypertrophy, Left Ventricular; Isoquinolines; Losartan; Male; Myocardial Infarction; Organ Size; Quinapril; Rats; Rats, Wistar; Tetrahydroisoquinolines	1998
Endogenous angiotensin II and bradykinin delay and attenuate the hypotension after N-type calcium channel blockade in conscious rabbits. Journal of cardiovascular pharmacology, 1998, Volume: 32, Issue:6 Topics: Adrenergic beta-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Baroreflex; Blood Pressure; Bradykinin; Calcium Channel Blockers; Dose-Response Relationship, Drug; Enalaprilat; Heart Rate; Hypotension; Losartan; Nasopharynx; omega-Conotoxin GVIA; Peptides; Pressoreceptors; Propranolol; Rabbits; Renin-Angiotensin System	1998
Angiotensin II-stimulated nitric oxide release from porcine pulmonary endothelium is mediated by angiotensin IV. Journal of the American Society of Nephrology : JASN, 1999, Volume: 10, Issue:3 Topics: Angiotensin II; Animals; Bradykinin; Cells, Cultured; Dose-Response Relationship, Drug; Drug Interactions; Endothelium, Vascular; Enzyme Activation; Enzyme Inhibitors; Losartan; NG-Nitroarginine Methyl Ester; Nitric Oxide; Nitric Oxide Synthase; Pulmonary Artery; Reference Values; Swine; Vasoconstrictor Agents	1999
Bradykinin and inhibition of angiotensin-converting enzyme in hypertension. The New England journal of medicine, 1999, Mar-25, Volume: 340, Issue:12 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Captopril; Drug Therapy, Combination; Humans; Hypertension; Losartan; Renin-Angiotensin System	1999
Bradykinin-dependent cardioprotective effects of losartan against ischemia and reperfusion in rat hearts. Journal of cardiovascular pharmacology, 1999, Volume: 33, Issue:5 Topics: Adenosine Triphosphate; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Coronary Circulation; In Vitro Techniques; Isoquinolines; Losartan; Male; Myocardial Reperfusion Injury; Myocardium; Phosphocreatine; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Tetrahydroisoquinolines; Ventricular Function, Left; Ventricular Pressure	1999
Protective role of the angiotensin AT2 receptor in a renal wrap hypertension model. Hypertension (Dallas, Tex. : 1979), 1999, Volume: 33, Issue:5 Topics: Analysis of Variance; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Cyclic GMP; Hypertension, Renovascular; Imidazoles; Kidney; Losartan; Nitric Oxide; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Vasodilation	1999
Effects of quinapril and losartan on insulin sensitivity in genetic hypertensive rats with different metabolic abnormalities. Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:1 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Chemical Analysis; Blood Pressure; Bradykinin; Drug Resistance; Drug Synergism; Glucose; Glucose Clamp Technique; Hypertension; Insulin; Isoquinolines; Losartan; Male; Quinapril; Rats; Rats, Inbred SHR; Tetrahydroisoquinolines	1999
The effects of angiotensin II on blood perfusion in the rat renal papilla. The Journal of physiology, 1999, Aug-15, Volume: 519 Pt 1 Topics: Angiotensin II; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Kidney Medulla; Laser-Doppler Flowmetry; Losartan; Nitroarginine; Nitroprusside; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Regional Blood Flow; Renal Circulation; Ultrasonography	1999
Differing effects of enalapril and losartan on renal medullary blood flow and renal interstitial hydrostatic pressure in spontaneously hypertensive rats. Journal of hypertension, 1999, Volume: 17, Issue:9 Topics: Adrenergic beta-Antagonists; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Enalapril; Hydrostatic Pressure; Kidney Medulla; Laser-Doppler Flowmetry; Losartan; Male; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renal Circulation	1999
Absence of nitrate tolerance after long-term treatment with ramipril: an endothelium-dependent mechanism. Journal of cardiovascular pharmacology, 1999, Volume: 34, Issue:4 Topics: Adrenergic beta-Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Thoracic; Bradykinin; Dose-Response Relationship, Drug; Drug Interactions; Drug Tolerance; Endothelium, Vascular; In Vitro Techniques; Losartan; Male; Nitrates; Nitric Oxide Synthase; Nitroglycerin; omega-N-Methylarginine; Ramipril; Rats; Rats, Wistar; Superoxides; Time Factors; Vasodilator Agents	1999
Effects of losartan on low-density lipoprotein apheresis. Therapeutic apheresis : official journal of the International Society for Apheresis and the Japanese Society for Apheresis, 1999, Volume: 3, Issue:4 Topics: Aldosterone; Antihypertensive Agents; Bradykinin; Combined Modality Therapy; Follow-Up Studies; Humans; Hyperlipoproteinemia Type II; Lipoproteins, LDL; Losartan; Male; Middle Aged; Plasmapheresis; Renin; Treatment Outcome	1999
Brain AT(2) receptor mediate vasodepressor response to footshocks: role of kinins and nitric oxide. Brain research bulletin, 2000, Mar-01, Volume: 51, Issue:4 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Brain; Electroshock; Enzyme Inhibitors; Extremities; Heart Rate; Imidazoles; Injections, Intraventricular; Losartan; Male; Nitric Oxide Synthase; Nitroarginine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Receptors, Angiotensin	2000
Paracrine effects of angiotensin-converting-enzyme- and angiotensin-II-receptor- inhibition on transcapillary glucose transport in humans. Life sciences, 2000, Volume: 66, Issue:10 Topics: Adult; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biological Transport; Bradykinin; Capillaries; Enalapril; Glucose; Humans; Hyperinsulinism; Losartan; Male; Receptors, Angiotensin	2000
Neuropeptide Y enhances potassium excretion by mechanisms distinct from those controlling sodium excretion. Canadian journal of physiology and pharmacology, 2000, Volume: 78, Issue:2 Topics: Aldosterone; Animals; Bradykinin; Humans; Indomethacin; Losartan; Male; Neuropeptide Y; Nifedipine; Potassium; Rats; Rats, Wistar; Sodium	2000
Angiotensin AT(2) receptors mediate vasodepressor response to footshock in rats. Role of kinins, nitric oxide and prostaglandins. European journal of pharmacology, 2000, Apr-07, Volume: 394, Issue:1 Topics: Animals; Blood Pressure; Bradykinin; Electroshock; Heart Rate; Imidazoles; Kinins; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Prostaglandins; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin	2000
Endothelin-1 attenuates bradykinin-induced hypotension in rats. European journal of pharmacology, 2000, Jun-02, Volume: 397, Issue:2-3 Topics: Administration, Oral; Animals; Blood Pressure; Bradykinin; Dose-Response Relationship, Drug; Enalapril; Endothelin-1; Hypotension; Injections, Intravenous; Losartan; Male; Rats; Rats, Wistar	2000
Role of bradykinins and nitric oxide in the AT2 receptor-mediated hypotension. Journal of human hypertension, 2000, Volume: 14 Suppl 1 Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Drug Administration Routes; Enzyme Inhibitors; Hot Temperature; Hypertension; Hypotension; Imidazoles; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Shock; Vasodilation	2000
Regional renal haemodynamics of angiotensin II infusion under prostaglandin, kinin or converting enzyme inhibition in the Wistar rat. Blood pressure, 2000, Volume: 9, Issue:2-3 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Aprotinin; Bradykinin; Enalapril; Hemodynamics; Ketoprofen; Kidney Medulla; Losartan; Male; Nitric Oxide; Prostaglandin Antagonists; Rats; Rats, Wistar; Renal Circulation	2000
Reinforcement of arteriolar myogenic activity by endogenous ANG II: susceptibility to dietary salt. American journal of physiology. Heart and circulatory physiology, 2000, Volume: 279, Issue:1 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Blood Pressure; Bradykinin; Diet, Sodium-Restricted; Losartan; Male; Microcirculation; Muscle, Skeletal; Muscle, Smooth, Vascular; Rats; Rats, Inbred WKY; Saralasin; Sodium, Dietary	2000
Myocardial protection by preconditioning of heart with losartan, an angiotensin II type 1-receptor blocker: implication of bradykinin-dependent and bradykinin-independent mechanisms. Circulation, 2000, Nov-07, Volume: 102, Issue:19 Suppl 3 Topics: Adrenergic beta-Antagonists; Angiotensin Receptor Antagonists; Angiotensins; Animals; Apoptosis; Bradykinin; Bradykinin Receptor Antagonists; Heart; In Vitro Techniques; Ischemic Preconditioning, Myocardial; Losartan; Myocardial Infarction; Myocardium; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Ventricular Function	2000
Acute administration of nicotine impairs the hypotensive responses to bradykinin in rats. European journal of pharmacology, 2001, Feb-16, Volume: 413, Issue:2-3 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Blood Pressure; Bradykinin; Dose-Response Relationship, Drug; Enalapril; Endothelium, Vascular; Ganglionic Stimulants; Hypotension; Losartan; Male; Nicotine; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2	2001
Angiotensin converting enzyme (ACE) and non-ACE dependent angiotensin II generation in resistance arteries from patients with heart failure and coronary heart disease. Journal of the American College of Cardiology, 2001, Mar-15, Volume: 37, Issue:4 Topics: Acetylcholine; Aged; Angina Pectoris; Angiotensin I; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Arteries; Bradykinin; Chymases; Enalaprilat; Female; Heart Failure; Humans; In Vitro Techniques; Losartan; Male; Middle Aged; Oligopeptides; Peptidyl-Dipeptidase A; Serine Endopeptidases; Vascular Resistance; Vasoconstriction	2001
Angiotensin II enhances noradrenaline release from sympathetic nerves of the rat prostate via a novel angiotensin receptor: implications for the pathophysiology of benign prostatic hyperplasia. The Journal of endocrinology, 2001, Volume: 171, Issue:1 Topics: Analysis of Variance; Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Captopril; CHO Cells; Cricetinae; Dose-Response Relationship, Drug; Imidazoles; Losartan; Male; Norepinephrine; Oligopeptides; Prostate; Prostatic Hyperplasia; Pyridines; Rats; Rats, Sprague-Dawley; Receptors, Angiotensin; Sympathetic Nervous System; Synaptic Transmission	2001
Effects of losartan on blood pressure and humoral factors in a patient who suffered from anaphylactoid reactions when treated with ACE inhibitors during LDL apheresis. Hypertension research : official journal of the Japanese Society of Hypertension, 2001, Volume: 24, Issue:5 Topics: Aldosterone; Anaphylaxis; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Component Removal; Blood Pressure; Bradykinin; Cholesterol, LDL; Humans; Hypotension; Losartan; Male; Middle Aged; Oligopeptides; Receptor, Angiotensin, Type 1; Renin	2001
Use of angiotensin-converting enzyme inhibitors in patients with diabetes and coronary artery disease. Current problems in cardiology, 2002, Volume: 27, Issue:1 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Bradykinin; Chymases; Coronary Artery Disease; Diabetic Angiopathies; Endothelium, Vascular; Fibrinolysis; Humans; Losartan; Oxidative Stress; Serine Endopeptidases	2002
Effects of antihypertensive therapy on intrarenal angiotensin and bradykinin levels in experimental renal insufficiency. Kidney international, 2002, Volume: 61, Issue:2 Topics: Aldosterone; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Body Weight; Bradykinin; Creatinine; Enalapril; Kidney; Losartan; Male; Nephrectomy; Nifedipine; Proteinuria; Rats; Rats, Wistar; Renin; Renin-Angiotensin System; Vasodilator Agents	2002
Microinjection of ANG II into paraventricular nucleus enhances cardiac sympathetic afferent reflex in rats. American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:6 Topics: Afferent Pathways; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Blood Pressure; Bradykinin; Denervation; Electric Stimulation; Heart; Heart Rate; Kidney; Losartan; Male; Microinjections; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reflex; Sinus of Valsalva; Sympathetic Nervous System; Vagotomy	2002
Angiotensin-converting enzyme inhibitors improve coronary flow reserve in dilated cardiomyopathy by a bradykinin-mediated, nitric oxide-dependent mechanism. Circulation, 2002, Jun-11, Volume: 105, Issue:23 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cardiomyopathy, Dilated; Coronary Circulation; Dogs; Dose-Response Relationship, Drug; Enalaprilat; Enzyme Inhibitors; Hemodynamics; Kinetics; Losartan; Nitric Oxide; Nitric Oxide Synthase; Nitroarginine; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B2; Receptors, Bradykinin; Regional Blood Flow; Vasodilator Agents	2002
Central AT1 receptors are involved in the enhanced cardiac sympathetic afferent reflex in rats with chronic heart failure. Basic research in cardiology, 2002, Volume: 97, Issue:4 Topics: Anesthetics, Local; Angiotensin II; Animals; Anti-Arrhythmia Agents; Bradykinin; Capsaicin; Heart Failure; Heart Ventricles; Hemodynamics; Injections, Intravenous; Injections, Intraventricular; Lidocaine; Ligation; Losartan; Male; Myocardial Infarction; Myocardium; Neurons, Afferent; Organ Size; Pericardium; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptors, Angiotensin; Reflex; Renin; Sympathetic Nervous System; Ventricular Function	2002
Contrasting effects of angiotensin type 1 and 2 receptors on nitric oxide release under pressure. Hypertension research : official journal of the Japanese Society of Hypertension, 2002, Volume: 25, Issue:5 Topics: Angiotensin II; Angiotensin Receptor Antagonists; Animals; Antihypertensive Agents; Aorta; Apoptosis; Bradykinin; Cell Count; Cells, Cultured; Endothelium, Vascular; Gene Expression; Glyceraldehyde-3-Phosphate Dehydrogenases; In Vitro Techniques; Losartan; Male; Nitrates; Nitric Oxide; Nitrites; Oxygen; Pressure; Rats; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin	2002
Vasopeptidase inhibitor omapatrilat induces profound insulin sensitization and increases myocardial glucose uptake in Zucker fatty rats: Studies comparing a vasopeptidase inhibitor, angiotensin-converting enzyme inhibitor, and angiotensin II type I recept Circulation, 2003, Apr-15, Volume: 107, Issue:14 Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Biological Transport; Blood Glucose; Bradykinin; Bradykinin Receptor Antagonists; Drug Synergism; Enzyme Inhibitors; Glucose; Glucose Clamp Technique; Insulin; Insulin Resistance; Losartan; Male; Myocardium; Neprilysin; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Protease Inhibitors; Pyridines; Ramipril; Rats; Rats, Zucker; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B2; Thiazepines	2003
Enalaprilat, losartan and LU 135252 in coronary blood flow regulation. European journal of clinical investigation, 2003, Volume: 33, Issue:5 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bradykinin; Coronary Circulation; Enalaprilat; Female; Losartan; Male; Phenylpropionates; Pyrimidines; Swine	2003
Coronary microvascular endothelial stunning after acute pressure overload in the conscious dog is caused by oxidant processes: the role of angiotensin II type 1 receptor and NAD(P)H oxidase. Circulation, 2003, Dec-09, Volume: 108, Issue:23 Topics: Acetophenones; Angiotensin II; Animals; Ascorbic Acid; Bradycardia; Bradykinin; Coronary Circulation; Cyclic N-Oxides; Dogs; Hypotension; Ligation; Losartan; Myocardial Stunning; Nitric Oxide; Oxidative Stress; Pressure; Reflex; Spin Labels; Superoxides; Veratrine	2003
Stimulation of cyclic GMP production via AT2 and B2 receptors in the pressure-overloaded aorta after banding. Hypertension (Dallas, Tex. : 1979), 2004, Volume: 43, Issue:6 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Valve Stenosis; Bradykinin; Bradykinin B2 Receptor Antagonists; Cyclic GMP; Hypertension; Imidazoles; Ligation; Losartan; Male; Mice; Mice, Inbred ICR; Models, Animal; Nitric Oxide; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Renin; RNA, Messenger; Up-Regulation; Vasoconstriction	2004
Flow-dependent dilation mediated by endogenous kinins requires angiotensin AT2 receptors. Circulation research, 2004, Jun-25, Volume: 94, Issue:12 Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Carotid Arteries; Hemorheology; Imidazoles; Losartan; Male; Mesenteric Arteries; Mice; Mice, Inbred C57BL; Mice, Knockout; Phenylephrine; Pyridines; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Tetrazoles; Tissue Kallikreins; Vasodilation; Vasodilator Agents	2004
Oxidant stress in kidneys of spontaneously hypertensive rats involves both oxidase overexpression and loss of extracellular superoxide dismutase. American journal of physiology. Renal physiology, 2004, Volume: 287, Issue:5 Topics: Acetophenones; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Bradykinin; Enalaprilat; Free Radical Scavengers; Immunoblotting; In Vitro Techniques; Kidney; Kidney Cortex; Losartan; NADPH Oxidases; Nitric Oxide; Nitric Oxide Donors; Nitric Oxide Synthase; Oxidative Stress; Oxygen Consumption; Rats; Rats, Inbred SHR; Rats, Inbred WKY; S-Nitroso-N-Acetylpenicillamine; Superoxide Dismutase	2004
Angiotensin-converting enzyme inhibition and angiotensin AT1-receptor antagonism equally improve endothelial vasodilator function in L-NAME-induced hypertensive rats. European journal of pharmacology, 2005, Jun-15, Volume: 516, Issue:3 Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Aorta, Thoracic; Blood Pressure; Bradykinin; Bradykinin Receptor Antagonists; Enalapril; Endothelium, Vascular; Enzyme Inhibitors; Hypertension; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase; Nitric Oxide Synthase Type III; Nitrites; Norepinephrine; Peptidyl-Dipeptidase A; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Systole; Vasoconstriction; Vasodilation; Vasodilator Agents	2005
ACE inhibitor and AT1 antagonist stimulate duodenal HCO3- secretion mediated by a common pathway - involvement of PG, NO and bradykinin. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society, 2005, Volume: 56, Issue:3 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Bicarbonates; Blood Pressure; Bradykinin; Dinoprostone; Duodenum; Enalapril; In Vitro Techniques; Losartan; Male; Nitric Oxide; Nitric Oxide Synthase; Prostaglandins; Rats; Rats, Sprague-Dawley; Renin-Angiotensin System; Signal Transduction	2005
Angiotensin II type 1 receptor antagonism improves endothelial vasodilator function in L-NAME-induced hypertensive rats by a kinin-dependent mechanism. Journal of hypertension, 2006, Volume: 24, Issue:1 Topics: 6-Ketoprostaglandin F1 alpha; Acetylcholine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Blood Pressure; Bradykinin; Bradykinin B2 Receptor Antagonists; Endothelium, Vascular; Gene Expression Regulation, Enzymologic; Hypertension; Kinins; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitrates; Nitric Oxide Synthase Type III; Nitrites; Nitroprusside; Rats; Rats, Wistar; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B2; RNA, Messenger; Vasodilation	2006
Systemic inhibition of the angiotensin-converting enzyme limits lipopolysaccharide-induced lung neutrophil recruitment through both bradykinin and angiotensin II-regulated pathways. Journal of immunology (Baltimore, Md. : 1950), 2006, Nov-15, Volume: 177, Issue:10 Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Bradykinin; Cell Migration Inhibition; Chemokine CXCL1; Chemokine CXCL2; Chemokines; Chemokines, CXC; Chemotaxis, Leukocyte; Down-Regulation; Female; Lipopolysaccharides; Losartan; Lung; Mice; Mice, Inbred C57BL; Mice, Knockout; Neutrophil Infiltration; Plasminogen Activator Inhibitor 1; Receptors, Bradykinin; Signal Transduction	2006
AT1 receptor blockade prevents microvascular dysfunction induced by ischemia/reperfusion injury. Journal of atherosclerosis and thrombosis, 2006, Volume: 13, Issue:5 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Bradykinin; Capillary Permeability; Cell Adhesion; Leukocyte Rolling; Leukocytes; Losartan; Male; Mesentery; Models, Animal; Nitric Oxide Synthase; Rats; Rats, Sprague-Dawley; Reperfusion Injury; Venules; Videotape Recording	2006
Angiotensin-converting enzyme inhibitor enhances liver regeneration following partial hepatectomy: involvement of bradykinin B2 and angiotensin AT1 receptors. Biological & pharmaceutical bulletin, 2007, Volume: 30, Issue:3 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Benzimidazoles; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Bromodeoxyuridine; Dose-Response Relationship, Drug; Hepatectomy; Hepatocyte Growth Factor; Hepatocytes; Lisinopril; Liver Regeneration; Losartan; Male; Rats; Rats, Sprague-Dawley; Receptor, Bradykinin B2; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tetrazoles; Time Factors	2007
ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin. The European respiratory journal, 2008, Volume: 31, Issue:2 Topics: Angiotensin II; Animals; Apoptosis; Bradykinin; Bronchoalveolar Lavage Fluid; Captopril; Disease Models, Animal; Enzyme-Linked Immunosorbent Assay; Immunohistochemistry; In Situ Nick-End Labeling; Inflammation Mediators; Losartan; Lung Diseases; Male; Peptidyl-Dipeptidase A; Pulmonary Gas Exchange; Random Allocation; Rats; Rats, Sprague-Dawley; Reference Values; Respiration, Artificial; Sensitivity and Specificity	2008
Angiotensin II type 2 receptor-mediated inhibition of norepinephrine release in isolated rat hearts. Journal of cardiovascular pharmacology, 2008, Volume: 52, Issue:2 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Angiotensin II Type 2 Receptor Blockers; Animals; Bradykinin; Heart; Imidazoles; In Vitro Techniques; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Norepinephrine; Oligopeptides; Phenylalanine; Pyridines; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System; Tranexamic Acid; Vasoconstrictor Agents	2008
Angiotensin II-mediated vasodilation is reduced in adult spontaneously hypertensive rats despite enhanced expression of AT2 receptors. Clinical and experimental pharmacology & physiology, 2009, Volume: 36, Issue:1 Topics: Acetylcholine; Aging; Angiotensin II; Animals; Blotting, Western; Bradykinin; Gene Expression Regulation; Imidazoles; Losartan; Mesenteric Arteries; NG-Nitroarginine Methyl Ester; Nitric Oxide Synthase; Peptide Fragments; Pyridines; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 2; Vasodilation	2009
The angiotensin II type 1 receptor antagonist Losartan binds and activates bradykinin B2 receptor signaling. Regulatory peptides, 2011, Feb-25, Volume: 167, Issue:1 Topics: Angiotensin II Type 1 Receptor Blockers; Angiotensins; Animals; Benzimidazoles; Binding, Competitive; Biphenyl Compounds; Bradykinin; Bradykinin B2 Receptor Antagonists; Chlorocebus aethiops; COS Cells; Hydrolysis; Kallikrein-Kinin System; Losartan; Myocardial Contraction; Phosphatidylinositols; Rats; Receptor, Angiotensin, Type 1; Receptor, Bradykinin B2; Renin-Angiotensin System; Signal Transduction; Tetrazoles	2011
[Angioedema due to losartan]. Medicina clinica, 2011, Sep-10, Volume: 137, Issue:6 Topics: Aged; Allopurinol; Angioedema; Angiotensin II Type 2 Receptor Blockers; Bradykinin; Diphenhydramine; Humans; Losartan; Male; Methylprednisolone	2011
Involvement of enhanced cardiac sympathetic afferent reflex in sympathetic activation in early stage of diabetes. Journal of applied physiology (Bethesda, Md. : 1985), 2012, Volume: 113, Issue:1 Topics: Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Anti-Arrhythmia Agents; Bradykinin; Capsaicin; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Diterpenes; Heart; Kidney; Lidocaine; Losartan; Male; Norepinephrine; Paraventricular Hypothalamic Nucleus; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1; Reflex; Sympathetic Nervous System; TRPV Cation Channels	2012
Intermittent losartan administration triggers cardiac post-conditioning in isolated rat hearts: role of BK2 receptors. PloS one, 2014, Volume: 9, Issue:2 Topics: Angiotensin Receptor Antagonists; Animals; Biphenyl Compounds; Bradykinin; Cardiotonic Agents; Heart; Hemodynamics; In Vitro Techniques; Irbesartan; Ischemic Postconditioning; Losartan; Male; Mitogen-Activated Protein Kinases; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 2; Receptor, Bradykinin B2; Systole; Tetrazoles	2014
The comparative efficacy of renin-angiotensin system blockers in schistosomal hepatic fibrosis. Experimental parasitology, 2018, Volume: 191 Topics: Amides; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Bradykinin; Fumarates; Lisinopril; Liver; Liver Cirrhosis; Losartan; Male; Mice; Mice, Inbred BALB C; Nitric Oxide Synthase Type III; p38 Mitogen-Activated Protein Kinases; Proto-Oncogene Mas; Proto-Oncogene Proteins; Receptors, G-Protein-Coupled; Renin; Renin-Angiotensin System; Schistosomiasis mansoni; Tissue Inhibitor of Metalloproteinase-1; Transforming Growth Factor beta1; Vasodilator Agents	2018