losartan and aspirin

losartan has been researched along with aspirin in 30 studies

Research

Studies (30)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (10.00)18.2507
2000's11 (36.67)29.6817
2010's14 (46.67)24.3611
2020's2 (6.67)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Andricopulo, AD; Moda, TL; Montanari, CA1
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ekins, S; Williams, AJ; Xu, JJ1
Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Babkov, DA; Babkova, VA; Borisov, AV; Borodkin, GS; Brigadirova, AA; Kolodina, AA; Litvinov, RA; Morkovnik, AS; Sochnev, VS; Sokolova, EV; Spasov, AA; Zhukowskaya, ON1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Abe, Y; Aki, Y; Kimura, S; Takenaka, I; Tamaki, T; Yoshida, H1
Agostoni, P; Guazzi, M; Melzi, G1
Cirigliano, MD; Nawarskas, JJ; Spinler, SA; Townsend, RR1
Browne, AE; Chatterjee, K; Grossman, W; Karliner, JS; Lee, RJ; Parmley, WW; Sievers, RE; Zhu, BQ1
Diener, HC1
McCall, AL1
Bobik, A1
De Champlain, J; Laplante, MA; Wu, R1
Dahlöf, B; de Faire, U; Devereux, RB; Edelman, JM; Fossum, E; Fyhrquist, F; Ibsen, H; Julius, S; Kjeldsen, SE; Kristianson, K; Lederballe-Pedersen, O; Lindholm, LH; Moan, A; Nieminen, MS; Omvik, P; Oparil, S; Snapinn, SM; Wedel, H1
Levinson, JR; MacRae, CA; Nahed, BV; Naunheim, MR; Ogilvy, CS; Walcott, BP1
Ding, Z; Goyal, T; Khaidakov, M; Lu, J; Mehta, JL; Mitra, S; Raina, S; Wang, X1
Ayyadevera, S; Ding, Z; Goyal, T; Hearnsberger, E; Khaidakov, M; Mehta, JL; Mitra, S; Wang, X1
Boytsov, S; Deev, A; Dupik, N; Kolos, I; Loukianov, M1
Caglar, I; Karakaya, O; Ugurlucan, M; Ungan, I; Vural, A1
Dunning, L; Ferrell, WR; Lockhart, JC; Mackenzie, A1
Luteijn, JM; Morris, JK; Oppenheimer, P; Taylor, D; Wald, NJ1
Kotegawa, T; Koya, Y; Machi, Y; Namiki, N; Shobu, Y; Uchida, S1
Moreno Vanegas, Y; Rivera, CE; Vishnu, P; Wadei, HM1
Dong, B; Dong, S; Li, L; Liu, Q; Shen, J; Yang, K; Zhao, Y; Zhou, X; Zhu, D1

Reviews

3 review(s) available for losartan and aspirin

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Apical hypertrophic cardiomyopathy--case report and review of the literature.
    Georgian medical news, 2013, Issue:216

    Topics: Acute Coronary Syndrome; Aspirin; Cardiomyopathy, Hypertrophic; Echocardiography; Electrocardiography; Humans; Losartan; Magnetic Resonance Imaging; Male; Middle Aged; Mutation

2013

Trials

5 trial(s) available for losartan and aspirin

ArticleYear
Comparison of changes in respiratory function and exercise oxygen uptake with losartan versus enalapril in congestive heart failure secondary to ischemic or idiopathic dilated cardiomyopathy.
    The American journal of cardiology, 1997, Dec-15, Volume: 80, Issue:12

    Topics: Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Cardiomyopathy, Dilated; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method; Enalapril; Exercise Test; Heart Failure; Hemodynamics; Humans; Losartan; Male; Middle Aged; Myocardial Ischemia; Oxygen Consumption; Pulmonary Diffusing Capacity; Pulmonary Ventilation; Respiratory Mechanics

1997
Effect of aspirin on blood pressure in hypertensive patients taking enalapril or losartan.
    American journal of hypertension, 1999, Volume: 12, Issue:8 Pt 1

    Topics: Adult; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Blood Pressure; Cross-Over Studies; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Interactions; Enalapril; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Patient Compliance; Thromboxane B2

1999
Reducing CVD risk in type 2 DM.
    Current diabetes reports, 2003, Volume: 3, Issue:5

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Aspirin; Behavior Therapy; Cardiovascular Diseases; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Dietary Carbohydrates; Dietary Fats; Exercise; Humans; Insulin, Isophane; Losartan; Risk Factors; Smoking Cessation

2003
The effect of losartan versus atenolol on cardiovascular morbidity and mortality in patients with hypertension taking aspirin: the Losartan Intervention for Endpoint Reduction in hypertension (LIFE) study.
    Journal of the American College of Cardiology, 2005, Sep-06, Volume: 46, Issue:5

    Topics: Adrenergic beta-Antagonists; Aged; Angiotensin II Type 1 Receptor Blockers; Aspirin; Atenolol; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Treatment Outcome

2005
Optimal medical treatment versus carotid endarterectomy: the rationale and design of the Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis (AMTEC) study.
    International journal of stroke : official journal of the International Stroke Society, 2015, Volume: 10, Issue:2

    Topics: Amlodipine; Antihypertensive Agents; Aspirin; Carotid Stenosis; Combined Modality Therapy; Endarterectomy, Carotid; Fibrinolytic Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Myocardial Infarction; Prospective Studies; Research Design; Russia; Stroke

2015

Other Studies

22 other study(ies) available for losartan and aspirin

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Hologram QSAR model for the prediction of human oral bioavailability.
    Bioorganic & medicinal chemistry, 2007, Dec-15, Volume: 15, Issue:24

    Topics: Administration, Oral; Biological Availability; Holography; Humans; Models, Biological; Models, Molecular; Molecular Structure; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship

2007
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
    Chemical research in toxicology, 2012, Oct-15, Volume: 25, Issue:10

    Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding

2012
Towards multi-target antidiabetic agents: Discovery of biphenyl-benzimidazole conjugates as AMPK activators.
    Bioorganic & medicinal chemistry letters, 2019, 09-01, Volume: 29, Issue:17

    Topics: AMP-Activated Protein Kinases; Animals; Benzimidazoles; Biphenyl Compounds; Cattle; Diabetes Mellitus, Type 2; Drug Evaluation, Preclinical; Enzyme Activators; Glycosylation; Hypoglycemic Agents; Lipopolysaccharides; Macrophages; Mice; Nitric Oxide; Serum Albumin, Bovine; Solubility; Structure-Activity Relationship

2019
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Effects of angiotensin II on isolated rabbit afferent arterioles.
    Japanese journal of pharmacology, 1994, Volume: 66, Issue:4

    Topics: Angiotensin II; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arginine; Arterioles; Aspirin; Biphenyl Compounds; Imidazoles; In Vitro Techniques; Indomethacin; Losartan; Lysine; Male; Nitric Oxide; omega-N-Methylarginine; Prostaglandin Antagonists; Prostaglandins; Rabbits; Renal Circulation; Tetrazoles; Vascular Resistance

1994
Comparative effects of aspirin with ACE inhibitor or angiotensin receptor blocker on myocardial infarction and vascular function.
    Journal of the renin-angiotensin-aldosterone system : JRAAS, 2003, Volume: 4, Issue:1

    Topics: Angiotensin I; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Bleeding Time; Captopril; Disease Models, Animal; Endothelium, Vascular; Female; Hemodynamics; Losartan; Myocardial Infarction; Myocardial Reperfusion Injury; Rats; Rats, Sprague-Dawley; Refractory Period, Electrophysiological; Vasodilation; Ventricular Fibrillation

2003
[Primary prevention of stroke. What helps--what does not help? The guidelines of the German Society of Neurology briefly summarized].
    MMW Fortschritte der Medizin, 2003, Volume: 145 Suppl 1

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Alcohol Drinking; Anticholesteremic Agents; Anticoagulants; Antihypertensive Agents; Arrhythmias, Cardiac; Aspirin; Atenolol; Atrial Fibrillation; Carotid Artery, Internal; Carotid Stenosis; Chlorthalidone; Clinical Trials as Topic; Diabetes Complications; Diuretics; Doxazosin; Female; Fibrinolytic Agents; Hormone Replacement Therapy; Humans; Hyperlipidemias; Hypertension; Hypolipidemic Agents; Life Style; Losartan; Male; Neurology; Platelet Aggregation Inhibitors; Practice Guidelines as Topic; Pravastatin; Primary Prevention; Risk Factors; Simvastatin; Smoking; Societies, Medical; Stroke

2003
Aspirin, superoxide anions and development of hypertension.
    Journal of hypertension, 2004, Volume: 22, Issue:4

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta; Aspirin; Cells, Cultured; Hypertension; Losartan; Luminescent Measurements; Male; Muscle, Smooth, Vascular; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxides; Time Factors; Vasoconstrictor Agents

2004
Prevention of angiotensin II-induced hypertension, cardiovascular hypertrophy and oxidative stress by acetylsalicylic acid in rats.
    Journal of hypertension, 2004, Volume: 22, Issue:4

    Topics: Angiotensin II; Animals; Antihypertensive Agents; Antioxidants; Aorta; Aspirin; Body Weight; Cells, Cultured; Hypertension; Hypertrophy, Left Ventricular; Losartan; Luminescent Measurements; Male; Muscle, Smooth, Vascular; Organ Size; Oxidative Stress; Rats; Rats, Sprague-Dawley; Superoxides; Time Factors; Vasoconstrictor Agents

2004
Arterial tortuosity syndrome with multiple intracranial aneurysms: a case report.
    Archives of neurology, 2011, Volume: 68, Issue:3

    Topics: Aged; Angiography; Antihypertensive Agents; Aorta; Aspirin; Circle of Willis; Connective Tissue Diseases; Coronary Vessels; Electrocardiography; Heart Block; Humans; Hypertension; Iliac Artery; Intracranial Aneurysm; Intracranial Arterial Diseases; Losartan; Male; Pacemaker, Artificial; Platelet Aggregation Inhibitors; Syncope; Syndrome

2011
Aspirin suppresses cardiac fibroblast proliferation and collagen formation through downregulation of angiotensin type 1 receptor transcription.
    Toxicology and applied pharmacology, 2012, Mar-15, Volume: 259, Issue:3

    Topics: Angiotensin II; Animals; Aspirin; Cell Proliferation; Collagen; Down-Regulation; Fibroblasts; Losartan; Matrix Metalloproteinases; Mice; Mice, Inbred C57BL; NADPH Oxidases; NF-kappa B; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Transcription, Genetic

2012
Aspirin downregulates angiotensin type 1 receptor transcription implications in capillary formation from endothelial cells.
    Journal of cardiovascular pharmacology, 2012, Volume: 60, Issue:2

    Topics: Angiogenesis Inhibitors; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Aspirin; Capillaries; Cells, Cultured; Down-Regulation; Enzyme Inhibitors; Human Umbilical Vein Endothelial Cells; Humans; Losartan; Mitogen-Activated Protein Kinases; NADPH Oxidases; Neovascularization, Physiologic; Receptor, Angiotensin, Type 1; RNA, Messenger; Salicylic Acid; Transcription, Genetic; Vascular Endothelial Growth Factor A

2012
Angiotensin II Type 1 receptor blockade protects endothelium-derived hyperpolarising factor-mediated relaxation in a rat model of monoarthritis.
    Life sciences, 2013, Jun-21, Volume: 92, Issue:23

    Topics: Angiotensin II Type 1 Receptor Blockers; Animals; Arteries; Arthritis, Experimental; Aspirin; Charybdotoxin; Disease Models, Animal; Dose-Response Relationship, Drug; Endothelium-Dependent Relaxing Factors; Female; Losartan; Muscle Relaxation; Muscle, Smooth, Vascular; Myography; NG-Nitroarginine Methyl Ester; Rats; Rats, Sprague-Dawley; Receptor, Angiotensin, Type 1

2013
Cost-benefit analysis of the polypill in the primary prevention of myocardial infarction and stroke.
    European journal of epidemiology, 2016, Volume: 31, Issue:4

    Topics: Aged; Aged, 80 and over; Amlodipine; Aspirin; Cardiovascular Agents; Case-Control Studies; Cohort Studies; Cost-Benefit Analysis; Humans; Hydrochlorothiazide; Losartan; Markov Chains; Middle Aged; Myocardial Infarction; Polypharmacy; Primary Prevention; Quality-Adjusted Life Years; Simvastatin; Stroke; United Kingdom

2016
Prediction of drug interaction between oral adsorbent AST-120 and concomitant drugs based on the in vitro dissolution and in vivo absorption behavior of the drugs.
    European journal of clinical pharmacology, 2016, Volume: 72, Issue:11

    Topics: Administration, Oral; Adsorption; Aluminum Hydroxide; Amlodipine; Aspirin; Carbon; Drug Interactions; Glycine; Humans; Intestinal Absorption; Losartan; Magnesium; Metoprolol; Models, Biological; Nifedipine; Oxides; Renal Insufficiency, Chronic; Solubility; Triazolam

2016
Post-transplant erythrocytosis refractory to ACE inhibitors and angiotensin receptor blockers.
    BMJ case reports, 2018, Jun-28, Volume: 2018

    Topics: Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Aspirin; Hematocrit; Humans; Kidney Transplantation; Losartan; Male; Middle Aged; Pancreas Transplantation; Phlebotomy; Polycythemia; Treatment Outcome

2018
Effects of Long-Term Intervention with Losartan, Aspirin and Atorvastatin on Vascular Remodeling in Juvenile Spontaneously Hypertensive Rats.
    Molecules (Basel, Switzerland), 2023, Feb-15, Volume: 28, Issue:4

    Topics: Animals; Antihypertensive Agents; Aspirin; Atorvastatin; Blood Pressure; Collagen; Hypertension; Interleukin-6; Losartan; Rats; Rats, Inbred SHR; Renin; Vascular Remodeling

2023