losartan has been researched along with amlodipine in 191 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 11 (5.76) | 18.2507 |
| 2000's | 75 (39.27) | 29.6817 |
| 2010's | 85 (44.50) | 24.3611 |
| 2020's | 20 (10.47) | 2.80 |
| Authors | Studies |
|---|---|
| Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Ambroso, JL; Ayrton, AD; Baines, IA; Bloomer, JC; Chen, L; Clarke, SE; Ellens, HM; Harrell, AW; Lovatt, CA; Reese, MJ; Sakatis, MZ; Taylor, MA; Yang, EY | 1 |
| Cantin, LD; Chen, H; Kenna, JG; Noeske, T; Stahl, S; Walker, CL; Warner, DJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Trimarco, B | 1 |
| Carney, S; Dahlöf, B; Lindholm, LH; Ostergren, J; Pentikäinen, PJ | 1 |
| Alhenc Gelas, F; Huang, W; Osborne-Pellegrin, MJ | 1 |
| Drewe, J; Gasser, P; Martina, B; Weinbacher, M | 1 |
| Barnes, CC; Lacourcière, Y; Wilson, TW | 1 |
| McAlister, FA; Sackett, D; Straus, S | 1 |
| Aranda, P; Casado, S; Fernández-Andrade, C; Guerra, L; Iversen, B; Russo, D; Zucchelli, P | 1 |
| Berg, KJ; Fauchald, P; Hartmann, A; Holdaas, H; Lund, K | 1 |
| Sever, PS | 1 |
| Anguita Sánchez, M | 1 |
| Anderson, TJ; Charbonneau, F; Elstein, E; Haber, H | 1 |
| Battegay, E; Dieterle, T; Martina, B; Weinbacher, M | 1 |
| Grote, L; Hedner, J; Kraiczi, H; Peker, Y | 1 |
| Bescós, M; Campistol, JM; Campos, B; Iñigo, P; Lario, S; Oppenheimer, F; Piera, C; Rivera, F | 1 |
| Díez, J; González, A; Larman, M; López, B; Martínez Ubago, JL; Querejeta, R; Varo, N | 1 |
| Liang, X; Su, M; Xie, X; Yu, G; Zhao, S | 1 |
| Díez, J; Fortuño, MA; González, A; Larman, M; López, B; Querejeta, R; Ravassa, S | 1 |
| Iwasaka, T; Masaki, H; Matsubara, H; Nishikawa, M; Nishiue, T; Shibasaki, Y | 1 |
| Studney, D | 1 |
| Kinoshita, M; Mabuchi, N; Maeda, K; Ohnishi, M; Tsutamoto, T; Tsutsui, T | 1 |
| Draganov, B; Holdaas, H; Høieggen, A; Jenssen, T; Os, I; Stenehjem, A | 1 |
| Iwasaka, T; Masaki, H; Matsubara, H; Nishiue, T; Shibasaki, Y | 1 |
| Suzuki, H | 2 |
| Gokhale, N; Pawar, D; Shahani, S | 1 |
| Deanfield, JE | 1 |
| Lester, MH; Resnick, LM | 1 |
| Liang, XQ; Yu, GL; Zheng, JQ | 1 |
| Xie, XM; Yu, GL; Zhou, P | 1 |
| Bilen, H; Cetinkaya, R; Keles, S; Odabas, AR; Selcuk, Y | 1 |
| Choi, KH; Choi, S; Goo, YS; Ha, SK; Han, DS; Kang, SW; Lee, HY; Park, HC; Xu, ZG | 1 |
| Kawecka-Jaszcz, K; Klocek, M; Rajzer, M | 1 |
| Bryce, A; Clarysse, L; Dass, B; Gamboa, R; Germano, G; Gilles, L; Gomez-Fernandez, P; Junren, Z; Kyle, C; Matadamas, N; Maxwell, T; Moreno-Heredia, E; Ortega-Gonzalez, G; Rodriguez, A; Rodriguez, F; Sanderson, JE; Smith, RD; Volpe, M | 1 |
| Aguirre, R; Andrade, CF; Ara, JM; Arias, M; Bernis, C; Campistol, JM; Galceran, JM; Luño, J; Marín, R; Mora, J; Poveda, R; Praga, M; Prat, MV; Rivera, F | 1 |
| Hayashi, M; Ideura, T; Iino, Y; Kawaguchi, Y; Kawamura, T; Kitajima, T; Koyama, A; Kuwahara, M; Shiigai, T; Sugisaki, T; Suzuki, H; Tomino, Y; Uchida, S; Umemura, S; Yamada, K; Yamazaki, T | 1 |
| Chiang, HT; Lin, SL; Liu, CP; Wu, SC | 1 |
| Ruilope, LM; Segura, J | 1 |
| Ghosh, AK; Ghosh, K | 1 |
| Hayashi, M; Ideura, T; Iino, Y; Kawaguchii, Y; Kawamura, T; Kitajima, T; Koyama, A; Kuwahara, M; Shiigai, T; Sugisaki, T; Suzuki, H; Tomino, Y; Uchida, S; Umemura, S; Yamada, K; Yamazaki, T | 1 |
| Bomalaski, JS; Clark, MA | 1 |
| Aralica, G; Batelja, L; Blagaic, AB; Hanzevacki, JS; Konjevoda, P; Kusec, V; Lovric-Bencic, M; Rogic, D; Seiwerth, S; Sikiric, P | 1 |
| Lindholm, LH | 1 |
| Brown, CA; Brown, SA; Cartier, LM; Dietrich, UM; Mathur, S; Munday, JS; Newell, MA; Sheldon, SE | 1 |
| Buniatian, MS; Oshchepkova, EV; Rogoza, AN; Zelveian, PA | 1 |
| Iwai, K; Matsumoto, M; Morimoto, S | 1 |
| Ando, D; Hirawa, N; Tochikubo, O; Umemura, S; Yasuda, G | 1 |
| Dikmen, T; Gul, S; Kaynar, K; Ovali, E; Ulusoy, S; Vanizor, B | 1 |
| Alvarez, V; Arias, M; Campistol, JM; Coto, E; Fernández Andrade, C; Galcerán, JM; Luño, J; Marín, R; Poveda, R; Praga, M; Rivera, F; Vallés, M | 1 |
| de Cavanagh, EM; Ferder, L; Inserra, F; Piotrkowski, B; Stella, I; Toblli, JE | 1 |
| Corradi, L; Destro, M; Fogari, E; Fogari, R; Mugellini, A; Rinaldi, A; Zoppi, A | 1 |
| Bia, MJ; Eisen, T; Formica, RN; Friedman, AL; Lorber, MI; Smith, JD | 1 |
| Iwasaka, T; Masaki, H; Matsubara, H; Matsumoto, N; Mori, Y; Nishikawa, M; Nishiue, T; Shibasaki, Y; Tamura, K | 1 |
| Egido, J; García-Puig, J; Gómez-Garre, D; Granados, R; Martín-Ventura, JL; Ruano, M; Sancho, T; Torres, R | 1 |
| Dallaverde, E; Feitosa, GS; Gomes, MA; Kohlmann, O; Mion, D; Oigman, W; Ribeiro, AB; Rocha, JC; Salgado, N | 1 |
| Rodriguez-Iturbe, B | 1 |
| Calabrò, R; Natale, F; Tedesco, MA | 1 |
| Kawano, Y | 1 |
| Aksnes, TA; Guptha, S; Kjeldsen, SE; Moan, A; Os, I; Reims, HM | 1 |
| Coelho, EB; da Silva, CA; Fazan, R; Nobre, F; Salgado, HC | 1 |
| Fukuoka, T; Higaki, J; Irita, J; Kurata, M; Manabe, S; Miyoshi, K; Murakami, K; Okura, T; Watanabe, S | 1 |
| Jin, HM; Pan, Y | 1 |
| Hannila-Handelberg, T; Hiltunen, TP; Kontula, K; Miettinen, HE; Paavonen, KJ; Pentikäinen, PJ; Strandberg, T; Suonsyrjä, T; Tikkanen, I; Tilvis, R; Virolainen, J | 1 |
| Abe, C; Akashiba, A; Ishimitsu, T; Kameda, T; Matsuoka, H; Minami, J; Takahashi, T | 1 |
| Chiara Cavallini, M; Palmieri, V; Pini, R | 1 |
| Hori, M; Yamamoto, K | 1 |
| Arora, R; Prabhakar, H; Rath, GP | 1 |
| de Cavanagh, EM; Ferder, L; Fraga, CG; Inserra, F; Piotrkowski, B; Stella, I; Toblli, JE | 1 |
| Fujita, T; Gohchi, K; Shimosawa, T; Yatomi, Y | 1 |
| Donner, K; Hannila-Handelberg, T; Hiltunen, TP; Kontula, K; Miettinen, HE; Paavonen, KJ; Pentikäinen, PJ; Strandberg, T; Suonsyrjä, T; Tikkanen, I; Tilvis, R | 1 |
| Dabek, J; Hannila-Handelberg, T; Hiltunen, TP; Kontula, K; Nieminen, MS; Oikarinen, L; Porthan, K; Suonsyrja, T; Toivonen, L; Vaananen, H; Viitasalo, M; Virolainen, J | 1 |
| Aksnes, TA; Flaa, A; Kjeldsen, SE; Mundal, HH; Rostrup, M; Sevre, K | 1 |
| Mourad, JJ; Waeber, B | 1 |
| Gregg, AM; Kloner, RA; Neutel, J; Roth, EM; Schwartz, B; Shi, H; Thakker, KM; Weinberger, MH; Weiss, R | 1 |
| Kuroyanagi, A; Matsubara, H; Sakamoto, T; Shiraishi, H; Shirayama, T | 1 |
| Higuchi, C; Naito, T; Nishimura, H; Otsuka, K; Sanaka, T; Tanihata, Y | 1 |
| Donner, K; Fodstad, H; Hannila-Handelberg, T; Hiltunen, TP; Kontula, K; Suonsyrjä, T | 1 |
| Hamamoto, Y; Honjo, S; Ikeda, H; Koshiyama, H; Minamikawa, J; Nabe, K; Nakamura, Y; Wada, Y | 1 |
| Guo, LL; Jin, HM; Pan, Y | 1 |
| Ahn, BO; Choi, SM; Kang, KK; Kim, JH; Seo, MJ; Yoo, M | 1 |
| Antikainen, M; Donner, KM; Hannila-Handelberg, T; Hiltunen, TP; Hirvonen, A; Kontula, K; Suonsyrjä, T; Tikkanen, I | 1 |
| Ando, C; Inoue, Y; Kodama, S; Mihara, H; Miyoshi, K; Niimura, H; Okamura, K; Sumi, S; Tojyo, H; Tsuchiya, Y; Urata, H; Yamanouchi, Y | 1 |
| Chandurkar, NB; Gupta, BS; Pareek, A; Sharma, R; Tiwari, D | 1 |
| Gleim, GW; Lam, C; Loeys, T; Manas, D; Santoro, E; Shahinfar, S; Strehlau, J; Webb, NJ; Wells, TG | 1 |
| Derosa, G; Fogari, R; Mugellini, A; Preti, P; Zoppi, A | 1 |
| Horio, T; Iwashima, Y; Kamide, K; Kawano, Y; Nakamura, S; Yoshihara, F | 1 |
| Bilo, G; Mancia, G; Parati, G; Schumacher, H | 1 |
| Goda, A; Hirotani, S; Lee-Kawabata, M; Masuyama, T; Matsumoto, M; Naito, Y; Nakaboh, A; Ohyanagi, M; Otsuka, M; Tsujino, T; Yoshida, C | 1 |
| Chayama, K; Fujii, Y; Fujimura, N; Hata, T; Hidaka, T; Higashi, Y; Idei, N; Kato, H; Kihara, Y; Liao, JK; Maruhashi, T; Mikami, S; Noma, K; Soga, J | 1 |
| Akehi, N; Ebisuno, S; Fukui, S; Hori, M; Horiguchi, Y; Katsube, Y; Kobayashi, K; Kodama, M; Ohtsu, H; Ota, M; Ozaki, H; Sakai, A; Shimonagata, T; Takayasu, K; Yamamoto, K; Yamazaki, T | 1 |
| Divya, O; Nagavalli, D; Sankar, AS; Santha, A; Vaidhyalingam, V | 1 |
| Gleim, GW; Lam, C; Le Bailly De Tilleghem, C; Shahinfar, S; Strehlau, J; Webb, NJ; Wells, TG | 1 |
| Hosseini, F; Mahmoudian, M; Nemati, F; Rahbar-Roshandel, N; Shafiei, M | 1 |
| Berl, T; de Graeff, PA; de Zeeuw, D; Holtkamp, FA; Lambers Heerspink, HJ; Laverman, GD; Lewis, JB; Packham, D; Parving, HH; Remuzzi, G | 1 |
| Balink, H; de Graaf, W; Grond, J; Hemmelder, MH | 1 |
| Corradi, L; Derosa, G; Destro, M; Fogari, R; Lazzari, P; Mugellini, A; Preti, P; Zoppi, A | 1 |
| Duprez, D; Ferdinand, KC; Purkayastha, D; Samuel, R; Wright, RF | 1 |
| Arimanickam, G | 1 |
| Khan, BV | 1 |
| Kawecka-Jaszcz, K; Rajzer, M; Undas, A; Wojciechowska, W | 1 |
| Donner, KM; Hannila-Handelberg, T; Hiltunen, TP; Kontula, K; Suonsyrjä, T | 1 |
| Derosa, G; Fogari, R; Lazzari, P; Maffioli, P; Mugellini, A; Zoppi, A | 1 |
| Chae, SC; Cho, SY; Hong, TJ; Jeong, JW; Jung, JW; Kang, SM; Kim, CH; Kim, JJ; Kim, MH; Kwon, J; Park, CG; Park, SH; Shin, DG; Yang, JY; Yoon, JH; Youn, JC | 1 |
| Duprez, D; Ferdinand, K; Purkayastha, D; Samuel, R; Wright, R | 1 |
| Chae, SC; Cho, SY; Choi, YJ; Hong, BK; Hong, TJ; Jeong, JW; Kim, CH; Kim, JJ; Kim, MH; Kwan, J; Park, CG; Park, SH; Yang, JY; Youn, HJ | 1 |
| Berwanger, O; Mion Júnior, D; Ortega, KC; Silva, GV; Tsuji, RL | 1 |
| Chen, S; Cui, Y; Jiang, J; Peng, J; Shen, J; Wang, W; Wu, Q | 1 |
| Cho, SY; Choi, YJ; Hong, BK; Kim, KS; Park, CG; Yang, JY; Yoon, HJ; Yoon, JH; Yoon, MH | 1 |
| Eguchi, K; Fukutomi, M; Hoshide, S; Kabutoya, T; Kario, K; Watanabe, T | 1 |
| Morris, JK; Wald, DS; Wald, NJ | 1 |
| Lin, J; Lin, L; Peng, F; Tang, H | 1 |
| Aoyama, T; Goto, M; Goto, N; Hiei, K; Iwasa, M; Kawai, N; Kida, K; Kobayashi, H; Kojima, S; Minagawa, T; Minatoguchi, S; Oda, M; Sugishita, F; Takai, K; Tanaka, R; Watanabe, I; Yamamoto, N; Yasue, T | 1 |
| Eguchi, K; Fukutomi, M; Hoshide, S; Kario, K; Watanabe, T | 1 |
| Ayaori, M; Higashi, K; Hosoai, H; Ikewaki, K; Kijima, F; Nakamura, H; Nashida, Y; Nishiwaki, M; Shige, H; Shimizu, S; Yamashita, T; Yokoyama, M | 1 |
| Boytsov, S; Deev, A; Dupik, N; Kolos, I; Loukianov, M | 1 |
| Hasebe, N; Kikuchi, K; Koyama, S; Maruyama, J; Morimoto, H; Morita, K; Saijo, Y; Sano, H; Sasagawa, Y; Sato, N; Sumitomo, K; Takehara, N; Takeuchi, T | 2 |
| Hayashi, S; Horio, T; Iwashima, Y; Kamide, K; Kawano, Y; Matayoshi, T; Nakamura, S; Ohta, Y; Takiuchi, S; Yoshihara, F | 1 |
| He, DH; Lin, JX; Ning, RB; Wang, HJ; Xu, CS; Zhang, LM | 1 |
| Soucek, M; Spinar, J; Vitovec, J | 1 |
| Pérez Carreño, JG; Romero, JD; Villar Centeno, JC | 1 |
| Dobrokhod, AS; Kushnir, SM; Radchenko, GD; Sirenko, YM; Torbas, OO | 1 |
| Guo, R; Li, R; Lv, C; Wang, B; Wang, X; Wei, C; Yao, H | 1 |
| Hong, YH; Kwon, HM; Lee, YS; Lim, JS; Nam, H; Shin, JW | 1 |
| He, DH; Lin, JX; Lin, LM; Ning, RB; Wang, HJ; Xu, CS; Zhang, LM | 1 |
| Chazova, IE; Martyniuk, TV | 1 |
| Lawrence Gould, A; Unniachan, S; Wu, D | 1 |
| Jeffers, BW; Wang, JG; Yan, P | 1 |
| Bedirian, R; Gismondi, RA; Ladeira, MC; Neves, MF; Oigman, W; Pozzobon, CR | 2 |
| Fujita, KP; Hanson, ME; Rajagopalan, S; Unniachan, S; Wu, D | 1 |
| Ahn, T; Bae, JH; Han, KR; Hyon, MS; Kim, WH; Kim, YK; Lee, SU; Lim, DS; Park, HK; Suh, SY | 1 |
| Azuma, K; Fujita, KP; Nishida, C; Numaguchi, H; Rakugi, H; Shimada, K; Shirakawa, M; Tsuchihashi, T; Yamaguchi, H | 2 |
| Nagata, M; Takase, B | 1 |
| Fu, SK; Gu, HF; Hu, C; Jin, HM; Liu, XL; Pan, LH; Pan, Y; Qiao, QY; Zhou, DC | 1 |
| Boerwinkle, E; Chapman, AB; Cooper-DeHoff, RM; Donner, KM; Frau, F; Glorioso, N; Glorioso, V; Gong, Y; Gums, JG; Hiltunen, TP; Johnson, JA; Kontula, KK; Ripatti, S; Saarela, J; Salvi, E; Sarin, AP; Turner, ST; Zaninello, R | 1 |
| Hayashi, M; Iino, Y; Kawamura, T; Kuwahara, M; Nangaku, M; Uchida, S | 1 |
| Bazaeva, EV; Boitsov, SA; Drapkina, OM; Luk'ianov, MM; Panov, AV; Shchukina, GN; Terent'ev, BP; Tiurin, VP | 1 |
| He, D; Lin, J; Zhang, L | 1 |
| Ishii, K; Ito, H; Iwakura, K; Kihara, H; Toh, N; Watanabe, H; Yoshikawa, J | 1 |
| Luteijn, JM; Morris, JK; Oppenheimer, P; Taylor, D; Wald, NJ | 1 |
| Brunette-Lawrey, E; Croft, F | 1 |
| Kotegawa, T; Koya, Y; Machi, Y; Namiki, N; Shobu, Y; Uchida, S | 1 |
| Cho, SM; Choi, Y; Jang, IJ; Kang, WH; Lee, S; Nam, KY; Yu, KS | 1 |
| Duran-Salgado, MB; Elizalde-Barrera, CI; Garro-Almendaro, AK; Rubio-Guerra, AF; Suarez-Cuenca, JA | 1 |
| Bhagat, S; Bharatam, PV; Chakraborti, AK; Handa, T; Jhajra, S; Singh, S | 1 |
| Agarwal, I; Ferket, BS; Fleischmann, KE; Hunink, MG; Khanji, M; Petersen, SE | 1 |
| de Leeuw, PW; Fagard, R; Kroon, AA | 1 |
| Al-Sharea, A; Dart, AM; Du, XJ; Gao, XM; Han, LP; Kiriazis, H; Moore, S; Murphy, AJ; Su, Y; Tsai, A | 1 |
| Fendrikova, AV; Pyhalova, NE; Sirotenko, DV; Skibitsky, VV | 1 |
| Alves, PH; Castro, CH; Colugnati, DB; Macedo, LM; Mendes, EP; Nunes, AD; Pedrino, GR; Santos, RA; Souza, AP | 1 |
| Chae, JK; Chae, SC; Chang, KY; Cho, JR; Choi, JH; Choi, YJ; Chun, KJ; Han, KR; Han, SH; Heo, JH; Hong, BK; Hong, SJ; Jeong, HS; Jeong, MH; Jung, J; Kang, HJ; Kang, SM; Kim, CH; Kim, DW; Kim, JJ; Kim, KS; Kim, SH; Kim, WS; Kim, YD; Kwan, J; Lee, BK; Lee, SK; Lee, SU; Park, CG; Park, SH; Shin, DG; Shin, JH; Won, KH | 1 |
| Cha, DH; Choi, JH; Choi, JY; Choi, KJ; Choi, SW; Hong, TJ; Jung, HO; Kim, KH; Kim, SM; Kim, SY; Kim, WS; Lee, HY; Lee, KJ; Oh, JH; Park, DG; Park, SW; Park, TH; Rha, SW; Rhee, MY; Ryu, DR; Shim, J; Song, PS; Yoo, BS | 1 |
| Brown, MJ; Caulfield, M; Cruickshank, JK; Ford, I; MacDonald, TM; Mackenzie, IS; McCann, GP; McInnes, G; Morant, S; Padmanabhan, S; Salsbury, J; Sever, P; Webb, DJ; Williams, B | 1 |
| Barnes, AP; Ellison, DH; Ferdaus, MZ; Kaul, S; McCormick, JA; Minnier, J; Nelson, JW | 1 |
| Ashcroft, JA | 1 |
| Ahn, YK; Chae, SC; Cho, EJ; Cho, MC; Choi, DJ; Chung, WJ; Ha, JW; Hong, SJ; Hong, TJ; Kim, CJ; Kim, SK; Kim, YJ; Lee, HY; Park, CG; Park, S; Shin, J; Sohn, IS; Sung, KC; Yoo, BS; Youn, HJ | 2 |
| Hebibovic, S; Jatic, Z; Rustempasic, E; Skopljak, A; Sukalo, A; Valjevac, A | 1 |
| Blot, WJ; Gonzales, H; Miller, R; Muñoz, D; Munro, H; Pappalardo, S; Reynolds, C; Song, W; Tousey, P; Uzoije, P; Walkley, D; Wang, TJ; White, C | 1 |
| Agabiti-Rosei, C; De Ciuceis, C; Paini, A; Rizzoni, D; Salvetti, M | 1 |
| Einollahi, B; Ghahroudi, MS; Hosseini, MS; Jafari, R; Javanbakht, M; Nikpoor, M; Rostami, Z | 1 |
| Chung, JY; Jang, IJ; Jung, JA; Kim, YI; Park, SI; Yoon, DY | 1 |
| Ahn, MS; Ahn, SG; Choi, E; Hong, KS; Kim, JY; Lee, JW; Lee, SH; Park, SM; Ryu, DR; Son, JW; Yoo, BS; Yoon, J; Youn, YJ | 1 |
| Glick, A; Johnson, C; Sista, V | 1 |
| Hong, SJ; Kim, HY; Kim, SY; Kim, W; Lim, SW; Park, S; Rhee, MY; Shin, J; Sung, KC | 1 |
| Macaulay, TE; Sheridan, E; Ward, S | 1 |
| Ahangari Maleki, M; Ansarin, K; Esmailnajad, A; Haghdoost, M; Kalami, N; Maleki, M; Nouri-Vaskeh, M; Rezaee, H; Sadeghi, A; Saleh, P; Sharifi, A; Soroureddin, Z; Taghizadieh, A; Varshochi, M; Zand, R | 1 |
| Aung, TKK; Chua, MWJ; Chuah, TY | 1 |
| Choi, Y; Chung, JY; Jeon, I; Jung, J; Moon, SJ; Park, SI; Yu, KS | 1 |
| Dabertrand, F; Ferris, HR; Greenstein, AS; Harraz, OF; Hill-Eubanks, DC; Koide, M; Longden, TA; Nelson, MT; Wellman, GC | 1 |
| An, H; Choi, J; Joo, HJ; Kim, EJ; Kim, YH; Lee, J; Yum, Y | 1 |
| Al-Mohammadi, OS; Al-Qaaneh, AM; Mustafa, SM; Obaid, WT; Rabaan, AA | 1 |
| Le Corre, P; Loas, G | 1 |
| Ankrah, D; Hollingworth, SA; Okeke, CC; Ruiz, F; Thacher, E; Uzochukwu, BSC | 1 |
| A Wartolowska, K; André, E; Biessels, GJ; Bousser, MG; Dichgans, M; Duering, M; Kerkhofs, D; Kopczak, A; Mansmann, U; Middeke, M; N Doubal, F; Norrving, B; Onkenhout, L; Rothwell, PM; S Stringer, M; Staals, J; Thrippleton, MJ; van den Brink, H; van Dinther, M; van Oostenbrugge, R; W Blair, G; Wardlaw, JM; Webb, AJ | 1 |
| Cho, DK; Cho, GY; Cho, JM; Heo, JH; Hong, SJ; Jeong, MH; Jung, JA; Kim, DH; Kim, SH; Kim, SY; Kim, W; Kwon, K; Lee, HY; Lee, JB; Lim, SW; Park, K; Park, S; Pyun, WB; Rha, SW; Rhee, MY; Shin, J; Sung, KC | 1 |
| Al Khawaja, AY; Hamdan, II; Khalil, EA; Mansour, RSH | 1 |
| Ahn, Y; Chae, IH; Hong, SJ; Hong, TJ; Kang, DH; Kim, BK; Kim, H; Kim, HS; Kim, MC; Kim, MH; Kim, SH; Kim, SY; Kim, W; Rhee, MY | 1 |
| Liang, H; Tang, T; Xie, M | 1 |
| Tchernev, G | 1 |
18 review(s) available for losartan and amlodipine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Angiotensin blockade in type 2 diabetes: what the new evidence tells us about renal and cardiac complications.
Topics: Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Biphenyl Compounds; Calcium Channel Blockers; Captopril; Cardiovascular Diseases; Clinical Trials as Topic; Diabetes Complications; Diabetes Mellitus; Diabetic Angiopathies; Diabetic Nephropathies; Humans; Irbesartan; Kidney Diseases; Losartan; Prognosis; Ramipril; Tetrazoles | 2002 |
[Type 2 diabetes and nephropathy--new studies, new treatment strategies?].
Topics: Amlodipine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Losartan; Randomized Controlled Trials as Topic; Renin-Angiotensin System | 2002 |
[Large scale clinical trials in prevention of end-stage renal disease due to type 2 diabetes with angiotensin receptor antagonists].
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Humans; Irbesartan; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Randomized Controlled Trials as Topic; Tetrazoles | 2002 |
[Evidence for the benefits of ACE inhibitors and AII antagonists in slowing progressive renal failure in diabetes].
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Biphenyl Compounds; Captopril; Clinical Trials as Topic; Disease Progression; Humans; Irbesartan; Kidney Failure, Chronic; Losartan; Tetrazoles; Treatment Outcome | 2002 |
Losartan and other angiotensin II antagonists for nephropathy in type 2 diabetes mellitus: a review of the clinical trial evidence.
Topics: Albuminuria; Amlodipine; Angiotensin II; Antihypertensive Agents; Biphenyl Compounds; Clinical Trials as Topic; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Humans; Irbesartan; Kidney Failure, Chronic; Losartan; Proteinuria; Tetrazoles | 2003 |
Serum uric acid-lowering therapies: where are we heading in management of hyperuricemia and the potential role of uricase.
Topics: Allopurinol; Amlodipine; Clinical Trials as Topic; Enzyme Inhibitors; Febuxostat; Gout; Humans; Hyperuricemia; Losartan; Pyrazoles; Thiazoles; Treatment Outcome; Urate Oxidase; Uric Acid; Xanthine Oxidase | 2004 |
[Treatment of hypertension in elderly patients with coronary heart disease].
Topics: Adrenergic beta-Antagonists; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Coronary Disease; Diuretics; Double-Blind Method; Drug Therapy, Combination; Enalapril; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Treatment Outcome | 2005 |
[HOSP study].
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Humans; Hypertension; Japan; Losartan; Middle Aged; Randomized Controlled Trials as Topic | 2006 |
[J-ELAN study (effect of losartan and amlodipine on left ventricular diastolic function in patients with mild-to-moderate hypertension)].
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan | 2007 |
Evaluating 24-h antihypertensive efficacy by the smoothness index: a meta-analysis of an ambulatory blood pressure monitoring database.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Benzoates; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Databases, Factual; Female; Humans; Losartan; Male; Ramipril; Randomized Controlled Trials as Topic; Telmisartan; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2010 |
Albuminuria and blood pressure, independent targets for cardioprotective therapy in patients with diabetes and nephropathy: a post hoc analysis of the combined RENAAL and IDNT trials.
Topics: Aged; Albuminuria; Amlodipine; Angiotensin Receptor Antagonists; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Cardiotonic Agents; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diabetic Nephropathies; Female; Heart Failure; Humans; Hypertension; Irbesartan; Losartan; Male; Middle Aged; Myocardial Infarction; Randomized Controlled Trials as Topic; Retrospective Studies; Risk Factors; Stroke; Tetrazoles; Treatment Outcome | 2011 |
The effect of amlodipine besylate, losartan potassium, olmesartan medoxomil, and other antihypertensives on central aortic blood pressure and biomarkers of vascular function.
Topics: Amlodipine; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Drug Therapy, Combination; Humans; Hypertension; Imidazoles; Losartan; Olmesartan Medoxomil; Reproducibility of Results; Tetrazoles | 2011 |
Indirect treatment comparison between fixed-dose-combinations of amlodipine/losartan and amlodipine/valsartan in blood pressure control.
Topics: Aged; Amlodipine; Amlodipine, Valsartan Drug Combination; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Multicenter Studies as Topic; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome | 2014 |
Effects of amlodipine and other classes of antihypertensive drugs on long-term blood pressure variability: evidence from randomized controlled trials.
Topics: Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Cardiovascular Diseases; Chlorthalidone; Enalapril; Humans; Hypertension; Lisinopril; Losartan; Randomized Controlled Trials as Topic | 2014 |
Evaluation of blood pressure reduction response and responder characteristics to fixed-dose combination treatment of amlodipine and losartan: a post hoc analysis of pooled clinical trials.
Topics: Adult; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Clinical Trials, Phase II as Topic; Clinical Trials, Phase III as Topic; Diastole; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Republic of Korea; Systole; Treatment Outcome | 2014 |
Reconsidering the Polypill for Management of Cardiovascular Risk Factors in Underserved Patients.
Topics: Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Drug Combinations; Heart Disease Risk Factors; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Risk Factors; Vulnerable Populations | 2021 |
Efficacy of single-pill combination in uncontrolled essential hypertension: A systematic review and network meta-analysis.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Essential Hypertension; Humans; Hydrochlorothiazide; Hypertension; Irbesartan; Losartan; Network Meta-Analysis; Telmisartan; Tetrazoles; Valine; Valsartan | 2023 |
106 trial(s) available for losartan and amlodipine
| Article | Year |
|---|---|
[The first clinical experience in Italy with angiotensin II receptor antagonists: results of a multicenter study on the efficacy and tolerance in arterial hypertension].
Topics: Adult; Aged; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biphenyl Compounds; Double-Blind Method; Female; Humans; Hypertension; Imidazoles; Italy; Losartan; Male; Middle Aged; Tetrazoles | 1995 |
Main results of the losartan versus amlodipine (LOA) study on drug tolerability and psychological general well-being. LOA Study Group.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Female; Heart Rate; Humans; Hypertension; Losartan; Male; Middle Aged; Quality of Life | 1997 |
Effects of losartan titrated to losartan/hydrochlorothiazide and amlodipine on blood pressure and peripheral capillary microcirculation in patients with mild-to-moderate hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Flow Velocity; Blood Pressure; Capillaries; Double-Blind Method; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Microcirculation; Middle Aged | 1998 |
The antihypertensive efficacy of losartan and amlodipine assessed with office and ambulatory blood pressure monitoring. Canadian Cozaar Hyzaar Amlodipine Trial Study Group.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Office Visits | 1998 |
Comparison of losartan and amlodipine in renally impaired hypertensive patients.
Topics: Adult; Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium; Creatine; Female; Humans; Hypertension, Renal; Losartan; Male; Middle Aged | 1998 |
Renal effects of losartan and amlodipine in hypertensive patients with non-diabetic nephropathy.
Topics: Adult; Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Biomarkers; Blood Pressure; Cross-Over Studies; Dextrans; Double-Blind Method; Female; Humans; Hypertension; Kidney; Kidney Diseases; Losartan; Middle Aged; Prospective Studies; Proteinuria | 1998 |
Comparative study of ACE-inhibition, angiotensin II antagonism, and calcium channel blockade on flow-mediated vasodilation in patients with coronary disease (BANFF study)
Topics: Aged; Amlodipine; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Blood Flow Velocity; Calcium Channel Blockers; Coronary Circulation; Coronary Disease; Drug Therapy, Combination; Enalapril; Endothelium, Vascular; Female; Humans; Isoquinolines; Losartan; Male; Middle Aged; Quinapril; Tetrahydroisoquinolines; Vasodilation | 2000 |
Effects of losartan titrated to Losartan/Hydrochlorothiazide and amlodipine on left ventricular mass in patients with mild-to-moderate hypertension. A double-blind randomized controlled study.
Topics: Adult; Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Body Mass Index; Double-Blind Method; Echocardiography; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Middle Aged; Treatment Outcome | 1999 |
Comparison of atenolol, amlodipine, enalapril, hydrochlorothiazide, and losartan for antihypertensive treatment in patients with obstructive sleep apnea.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Double-Blind Method; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Single-Blind Method; Sleep Apnea, Obstructive; Sodium Chloride Symporter Inhibitors | 2000 |
Effects of losartan and amlodipine on intrarenal hemodynamics and TGF-beta(1) plasma levels in a crossover trial in renal transplant recipients.
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cross-Over Studies; Endothelin-1; Female; Hemodynamics; Humans; Kidney; Kidney Transplantation; Losartan; Male; Middle Aged; Renal Circulation; Renin; Transforming Growth Factor beta; Transforming Growth Factor beta1 | 2001 |
Usefulness of serum carboxy-terminal propeptide of procollagen type I in assessment of the cardioreparative ability of antihypertensive treatment in hypertensive patients.
Topics: Adult; Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Biopsy; Blood Pressure; Collagen; Endomyocardial Fibrosis; Female; Heart; Humans; Hypertension; Losartan; Male; Middle Aged; Myocardium; Patient Compliance; Peptide Fragments; Predictive Value of Tests; Procollagen; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Remission Induction; Treatment Outcome; Ventricular Function, Left; White People | 2001 |
Stimulation of cardiac apoptosis in essential hypertension: potential role of angiotensin II.
Topics: Adult; Aged; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Apoptosis; bcl-2-Associated X Protein; Blood Pressure; Calcium Channel Blockers; Female; Heart Ventricles; Humans; Hypertension; Losartan; Male; Middle Aged; Myocardium; Proto-Oncogene Proteins; Proto-Oncogene Proteins c-bcl-2; Receptor, Angiotensin, Type 1 | 2002 |
Angiotensin II type 1 receptor antagonist, losartan, causes regression of left ventricular hypertrophy in end-stage renal disease.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Echocardiography; Enalapril; Female; Heart Ventricles; Humans; Hypertension; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Receptor, Angiotensin, Type 1; Renal Dialysis | 2002 |
[Angiotensin II type 1 antagonist suppress left ventricular hypertrophy and myocardial fibrosis in patient with end stage renal disease (ESRD)].
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Cardiomyopathies; Enalapril; Female; Fibrosis; Humans; Hypertrophy, Left Ventricular; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Myocardium; Renal Dialysis | 2002 |
Efficacy and safety of losartan-amplodipine combination--an Indian postmarketing surveillance experience.
Topics: Adult; Aged; Amlodipine; Blood Pressure Determination; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hypertension; India; Losartan; Male; Middle Aged; Product Surveillance, Postmarketing; Treatment Outcome | 2002 |
[Effect of losartan and amilodipine on the platelet activation and renal function in patients with mild and moderate hypertension].
Topics: Amlodipine; Antihypertensive Agents; Female; Humans; Hypertension; Kidney; Kidney Function Tests; Losartan; Male; Middle Aged; P-Selectin; Platelet Activation | 2002 |
The effect of high dose losartan on erythropoietin resistance in patients undergoing haemodialysis.
Topics: Adult; Amlodipine; Anemia; Angiotensin Receptor Antagonists; Antihypertensive Agents; Dose-Response Relationship, Drug; Drug Resistance; Erythropoietin; Female; Humans; Hypertension; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Prospective Studies; Recombinant Proteins; Renal Dialysis | 2003 |
Effect of losartan and amlodipine on proteinuria and transforming growth factor-beta1 in patients with IgA nephropathy.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Female; Glomerulonephritis, IGA; Humans; Hypertension; Losartan; Male; Middle Aged; Proteinuria; Transforming Growth Factor beta; Transforming Growth Factor beta1; Treatment Outcome | 2003 |
Effect of amlodipine, quinapril, and losartan on pulse wave velocity and plasma collagen markers in patients with mild-to-moderate arterial hypertension.
Topics: Adult; Aldosterone; Amlodipine; Antihypertensive Agents; Biomarkers; Blood Flow Velocity; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Collagen; Compliance; Echocardiography; Elasticity; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Pulsatile Flow; Quinapril; Severity of Illness Index; Tetrahydroisoquinolines | 2003 |
Comparison of the blood pressure-lowering effects and tolerability of Losartan- and Amlodipine-based regimens in patients with isolated systolic hypertension.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged | 2003 |
Antiproteinuric efficacy of losartan in comparison with amlodipine in non-diabetic proteinuric renal diseases: a double-blind, randomized clinical trial.
Topics: Adult; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus; Double-Blind Method; Female; Humans; Kidney Diseases; Losartan; Male; Middle Aged; Prospective Studies; Proteinuria; Transforming Growth Factor beta; Treatment Outcome | 2003 |
Interim evidence of the renoprotective effect of the angiotensin II receptor antagonist losartan versus the calcium channel blocker amlodipine in patients with chronic kidney disease and hypertension: a report of the Japanese Losartan Therapy Intended for
Topics: Adult; Aged; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension, Renal; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Proteinuria | 2003 |
Prospective and randomized study of the antihypertensive effect and tolerability of three antihypertensive agents, losartan, amlodipine, and lisinopril, in hypertensive patients.
Topics: Aged; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Cough; Female; Humans; Lisinopril; Losartan; Male; Middle Aged; Prospective Studies | 2004 |
Renoprotective effect of losartan in comparison to amlodipine in patients with chronic kidney disease and hypertension--a report of the Japanese Losartan Therapy Intended for the Global Renal Protection in Hypertensive Patients (JLIGHT) study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Female; Humans; Hypertension, Renal; Japan; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Proteinuria; Treatment Outcome | 2004 |
Effects of losartan and amlodipine on urinary albumin excretion and ambulatory blood pressure in hypertensive type 2 diabetic patients with overt nephropathy.
Topics: Adult; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Female; Heart Rate; Humans; Hypertension; Losartan; Male; Middle Aged | 2005 |
Effect of losartan and amlodipine on left ventricular diastolic function in patients with mild-to-moderate hypertension (J-ELAN): rationale and design.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Diastole; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Patient Selection; Research Design; Ventricular Dysfunction, Left | 2006 |
Losartan and prevention of atrial fibrillation recurrence in hypertensive patients.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Atrial Fibrillation; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Losartan; Male; Middle Aged; Recurrence | 2006 |
A randomized trial comparing losartan with amlodipine as initial therapy for hypertension in the early post-transplant period.
Topics: Adult; Aged; Amlodipine; Blood Pressure Determination; Chi-Square Distribution; Dose-Response Relationship, Drug; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Hypertension; Kidney Failure, Chronic; Kidney Transplantation; Losartan; Male; Middle Aged; Probability; Risk Assessment; Severity of Illness Index; Treatment Outcome | 2006 |
Impact of the angiotensin II receptor antagonist, losartan, on myocardial fibrosis in patients with end-stage renal disease: assessment by ultrasonic integrated backscatter and biochemical markers.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Collagen; Double-Blind Method; Echocardiography; Enalapril; Female; Fibrosis; Humans; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Myocardium; Peptide Fragments; Procollagen | 2005 |
Losartan improves resistance artery lesions and prevents CTGF and TGF-beta production in mild hypertensive patients.
Topics: Adult; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Arteries; Connective Tissue Growth Factor; Humans; Hypertension; Immediate-Early Proteins; Immunohistochemistry; Intercellular Signaling Peptides and Proteins; Losartan; Middle Aged; Reference Values; Transforming Growth Factor beta; Vascular Resistance | 2006 |
[The "LOTHAR" study: evaluation of efficacy and tolerability of the fixed combination of amlodipine and losartan in the treatment of essential hypertension].
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure Monitoring, Ambulatory; Chi-Square Distribution; Double-Blind Method; Drug Therapy, Combination; Female; Glucose; Humans; Hypertension; Lipid Metabolism; Losartan; Male; Middle Aged; Statistics, Nonparametric; Time Factors | 2006 |
Effects of monotherapy and combination therapy on blood pressure control and target organ damage: a randomized prospective intervention study in a large population of hypertensive patients.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Carbazoles; Cardiovascular Diseases; Carvedilol; Drug Therapy, Combination; Enalapril; Humans; Hypertension; Losartan; Male; Middle Aged; Propanolamines; Ultrasonography | 2006 |
Improved insulin sensitivity with the angiotensin II-receptor blocker losartan in patients with hypertension and other cardiovascular risk factors.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Glucose; Blood Pressure; Calcium Channel Blockers; Cardiovascular Diseases; Cross-Over Studies; Double-Blind Method; Female; Glucose Clamp Technique; Heart Rate; Humans; Hypertension; Insulin; Insulin Resistance; Lipids; Losartan; Male; Middle Aged; Risk Factors; Treatment Outcome; Uric Acid; Vasodilation | 2006 |
The effect of losartan and amlodipine on serum adiponectin in Japanese adults with essential hypertension.
Topics: Adiponectin; Adult; Aged; Amlodipine; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Prospective Studies | 2006 |
Angiotensin type-1 receptor blockade with losartan increases insulin sensitivity and improves glucose homeostasis in subjects with type 2 diabetes and nephropathy.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Glucose; C-Peptide; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Fasting; Female; Glycated Hemoglobin; Homeostasis; Humans; Insulin; Insulin Resistance; Losartan; Male; Middle Aged; Proteinuria; Time Factors; Treatment Outcome | 2007 |
Predictors of antihypertensive drug responses: initial data from a placebo-controlled, randomized, cross-over study with four antihypertensive drugs (The GENRES Study).
Topics: Adrenergic beta-Antagonists; Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Bisoprolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Cross-Over Studies; Diuretics; Double-Blind Method; Drug Therapy, Combination; Finland; Genetic Variation; Genotype; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Phenotype; Predictive Value of Tests; Prospective Studies; Reproducibility of Results; Time Factors; Treatment Outcome | 2007 |
Long-term efficacy of combination therapy with losartan and low-dose hydrochlorothiazide in patients with uncontrolled hypertension.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Treatment Outcome | 2007 |
Effectiveness of add-on low-dose diuretics in combination therapy for hypertension: losartan/hydrochlorothiazide vs. candesartan/amlodipine.
Topics: Aged; Amlodipine; Antihypertensive Agents; Asian People; Benzimidazoles; Biphenyl Compounds; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Japan; Losartan; Male; Middle Aged; Prospective Studies; Tetrazoles; Treatment Outcome | 2007 |
Laboratory tests as predictors of the antihypertensive effects of amlodipine, bisoprolol, hydrochlorothiazide and losartan in men: results from the randomized, double-blind, crossover GENRES Study.
Topics: Adult; Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Pressure; Calcium; Cross-Over Studies; Double-Blind Method; Forecasting; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Renin; Sodium; Treatment Outcome | 2008 |
Short-term electrophysiological effects of losartan, bisoprolol, amlodipine, and hydrochlorothiazide in hypertensive men.
Topics: Action Potentials; Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Pressure; Cross-Over Studies; Double-Blind Method; Electrocardiography; Electrophysiology; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Time Factors; Treatment Outcome; Ventricular Function | 2009 |
Effects on plasma noradrenaline may explain some of the improved insulin sensitivity seen by AT-1 receptor blockade.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Cross-Over Studies; Double-Blind Method; Electrocardiography; Female; Follow-Up Studies; Heart Rate; Humans; Hypertension; Insulin Resistance; Losartan; Male; Middle Aged; Norepinephrine; Sensitivity and Specificity; Treatment Outcome | 2008 |
Blood pressure control with amlodipine add-on therapy in patients with hypertension and diabetes: results of the Amlodipine Diabetic Hypertension Efficacy Response Evaluation Trial.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Quinapril; Tetrahydroisoquinolines | 2008 |
Losartan decreased premature ventricular contractions in patients with hypertension.
Topics: Aged; Amlodipine; Anti-Arrhythmia Agents; Enalapril; Humans; Hypertension; Losartan; Middle Aged; Ventricular Premature Complexes | 2009 |
Losartan elevates the serum high-molecular weight-adiponectin isoform and concurrently improves insulin sensitivity in patients with impaired glucose metabolism.
Topics: Adiponectin; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; Glucose Intolerance; Humans; Insulin Resistance; Losartan; Male; Middle Aged; Molecular Weight; Receptors, Cell Surface; Renin-Angiotensin System; Treatment Outcome | 2008 |
Renin-angiotensin system and alpha-adducin gene polymorphisms and their relation to responses to antihypertensive drugs: results from the GENRES study.
Topics: Adult; Amlodipine; Angiotensinogen; Antihypertensive Agents; Bisoprolol; Blood Pressure; Calmodulin-Binding Proteins; Humans; Hydrochlorothiazide; Losartan; Male; Middle Aged; Peptidyl-Dipeptidase A; Polymorphism, Genetic; Receptor, Angiotensin, Type 1; Renin-Angiotensin System | 2009 |
Comparison of effects of amlodipine and angiotensin receptor blockers on the intima-media thickness of carotid arterial wall (AAA study: amlodipine vs. ARB in atherosclerosis study).
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Calcium Channel Blockers; Carotid Arteries; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Tunica Intima; Tunica Media | 2009 |
Adiponectin is positively associated with insulin resistance in subjects with type 2 diabetic nephropathy and effects of angiotensin II type 1 receptor blocker losartan.
Topics: Adiponectin; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Nephropathies; Female; Glomerular Filtration Rate; Humans; Insulin; Insulin Resistance; Kidney Failure, Chronic; Losartan; Male; Middle Aged; Proteinuria; Renal Insufficiency, Chronic; Renin-Angiotensin System | 2009 |
CYP2C9 genotype modifies activity of the renin-angiotensin-aldosterone system in hypertensive men.
Topics: Adult; Aldosterone; Amlodipine; Antihypertensive Agents; Aryl Hydrocarbon Hydroxylases; Bisoprolol; Cross-Over Studies; Cytochrome P-450 CYP2C9; Double-Blind Method; Drug Resistance; Electrolytes; Gene Frequency; Genotype; Humans; Hypertension, Renal; Losartan; Male; Middle Aged; Placebos; Renin; Renin-Angiotensin System | 2009 |
Additive antihypertensive and antihypertrophic effects of long-acting Ca blockers in uncontrolled hypertensive patients with angiotensin-receptor blocker based treatment.
Topics: Aged; Amlodipine; Benzimidazoles; Biphenyl Compounds; Calcium Channel Blockers; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Nifedipine; Tetrazoles | 2009 |
Efficacy and tolerability of a fixed-dose combination of metoprolol extended release/amlodipine in patients with mild-to-moderate hypertension: a randomized, parallel-group, multicentre comparison with losartan plus amlodipine.
Topics: Adolescent; Adrenergic beta-Antagonists; Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Electrolytes; Female; Heart Rate; Humans; Losartan; Male; Metoprolol; Middle Aged; Young Adult | 2010 |
Randomized, double-blind, controlled study of losartan in children with proteinuria.
Topics: Adolescent; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Child; Child, Preschool; Creatinine; Double-Blind Method; Europe; Female; Humans; Hypertension; Infant; Losartan; Male; Proteinuria; Time Factors; Treatment Outcome; United States | 2010 |
Valsartan addition to amlodipine is more effective than losartan addition in hypertensive patients inadequately controlled by amlodipine.
Topics: Adult; Aged; Amlodipine; Anthracenes; Antihypertensive Agents; Blood Pressure; Cross-Over Studies; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Tetrazoles; Valine; Valsartan | 2010 |
Blood pressure and medication during long-term antihypertensive therapy based on morning home SBP in hypertensive patients: Hypertension Control Based on Home Systolic Pressure (HOSP) substudy.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Drug Therapy, Combination; Feasibility Studies; Female; Humans; Hypertension; Japan; Losartan; Male; Middle Aged; Pilot Projects; Time Factors; Treatment Outcome | 2010 |
Role of plasma aldosterone concentration in regression of left-ventricular mass following antihypertensive medication.
Topics: Adult; Aged; Aldosterone; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Female; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Middle Aged; Ventricular Dysfunction, Left | 2011 |
Calcium channel blocker and Rho-associated kinase activity in patients with hypertension.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Case-Control Studies; Cross-Sectional Studies; Double-Blind Method; Female; Humans; Hypertension; Leukocytes; Losartan; Male; Middle Aged; rho-Associated Kinases | 2011 |
The effect of losartan and amlodipine on left ventricular diastolic function and atherosclerosis in Japanese patients with mild-to-moderate hypertension (J-ELAN) study.
Topics: Adrenergic alpha-Antagonists; Aged; Amlodipine; Angiotensin II Type 2 Receptor Blockers; Antihypertensive Agents; Asian People; Atherosclerosis; Calcium Channel Blockers; Carotid Arteries; Diabetes Mellitus; Diuretics; Drug Therapy, Combination; Dyslipidemias; Female; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Middle Aged; Platelet Aggregation Inhibitors; Treatment Outcome; Ventricular Function, Left | 2011 |
Efficacy and safety of losartan in children with Alport syndrome--results from a subgroup analysis of a prospective, randomized, placebo- or amlodipine-controlled trial.
Topics: Adolescent; Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Child; Child, Preschool; Double-Blind Method; Female; Follow-Up Studies; Humans; Hypertension; Infant; Losartan; Male; Nephritis, Hereditary; Prognosis; Prospective Studies; Proteinuria; Survival Rate; Treatment Outcome; Young Adult | 2011 |
Losartan and amlodipine on myocardial structure and function: a prospective, randomized, clinical trial.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diastole; Echocardiography; Female; Fibrosis; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Male; Middle Aged; Myocardium; Prospective Studies; Treatment Outcome; Ventricular Dysfunction, Left | 2012 |
Combination angiotensin-receptor blocker (ARB)/calcium channel blocker with HCTZ vs the maximal recommended dose of an ARB with HCTZ in patients with stage 2 hypertension: the exforge as compared to losartan treatment in stage 2 systolic hypertension (EXA
Topics: Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Severity of Illness Index; Tetrazoles; Treatment Outcome; United States; Valine; Valsartan | 2011 |
Plasma fibrin clot properties in arterial hypertension and their modification by antihypertensive medication.
Topics: Adult; Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Coagulation; Female; Fibrin; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Quinapril; Tetrahydroisoquinolines | 2012 |
Effects of losartan and amlodipine alone or combined with simvastatin in hypertensive patients with nonalcoholic hepatic steatosis.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Body Mass Index; Body Weight; Double-Blind Method; Drug Therapy, Combination; Fatty Liver; Female; Glucose Clamp Technique; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Inflammation Mediators; Insulin Resistance; Lipids; Losartan; Male; Middle Aged; Simvastatin; Ultrasonography | 2012 |
Comparative efficacy and safety profile of amlodipine 5 mg/losartan 50 mg fixed-dose combination and amlodipine 10 mg monotherapy in hypertensive patients who respond poorly to amlodipine 5 mg monotherapy: an 8-week, multicenter, randomized, double-blind
Topics: Adult; Amlodipine; Analysis of Variance; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chi-Square Distribution; Dose-Response Relationship, Drug; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Republic of Korea; Time Factors; Treatment Outcome | 2011 |
Ambulatory blood pressure response to triple therapy with an angiotensin-receptor blocker (ARB), calcium-channel blocker (CCB), and HCTZ versus dual therapy with an ARB and HCTZ.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Tetrazoles; Valine; Valsartan | 2011 |
Evaluation of the dose-response relationship of amlodipine and losartan combination in patients with essential hypertension: an 8-week, randomized, double-blind, factorial, phase II, multicenter study.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged | 2012 |
Comparison of the efficacy and safety of fixed-dose amlodipine/losartan and losartan in hypertensive patients inadequately controlled with losartan: a randomized, double-blind, multicenter study.
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Republic of Korea; Time Factors; Treatment Outcome | 2012 |
Change in high-sensitive cardiac troponin T on hypertensive treatment.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Biomarkers; Blood Pressure; Calcium Channel Blockers; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Natriuretic Peptide, Brain; Troponin T | 2013 |
Randomized Polypill crossover trial in people aged 50 and over.
Topics: Aged; Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Blood Pressure; Cardiovascular Diseases; Cross-Over Studies; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypercholesterolemia; Hypertension; Losartan; Male; Middle Aged; Placebos; Simvastatin | 2012 |
Comparative effect of candesartan and amlodipine, and effect of switching from valsartan, losartan, telmisartan and olmesartan to candesartan, on early morning hypertension and heart rate.
Topics: Aged; Amlodipine; Antihypertensive Agents; Benzimidazoles; Benzoates; Biphenyl Compounds; Drug Substitution; Female; Heart Rate; Humans; Hypertension; Imidazoles; Losartan; Male; Middle Aged; Prospective Studies; Telmisartan; Tetrazoles; Valine; Valsartan | 2013 |
Low-grade inflammation and ambulatory blood pressure response to antihypertensive treatment: the ALPHABET study.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Inflammation; Losartan; Male; Middle Aged; Treatment Outcome | 2013 |
Efficacy and effects on lipid metabolism of combination treatment with losartan + hydrochlorothiazide versus losartan + amlodipine: a 48-week prospective, multicenter, randomized, open-label trial.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Lipid Metabolism; Losartan; Male; Middle Aged; Prospective Studies | 2013 |
Optimal medical treatment versus carotid endarterectomy: the rationale and design of the Aggressive Medical Treatment Evaluation for Asymptomatic Carotid Artery Stenosis (AMTEC) study.
Topics: Amlodipine; Antihypertensive Agents; Aspirin; Carotid Stenosis; Combined Modality Therapy; Endarterectomy, Carotid; Fibrinolytic Agents; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Myocardial Infarction; Prospective Studies; Research Design; Russia; Stroke | 2015 |
Combination of antihypertensive therapy in the elderly, multicenter investigation (CAMUI) trial: results after 1 year.
Topics: Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Calcium Channel Blockers; Cognition; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male | 2013 |
Control of home blood pressure with an amlodipine- or losartan-based regimen and progression of carotid artery intima-media thickness in hypertensive patients: the HOSP substudy.
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Carotid Intima-Media Thickness; Circadian Rhythm; Disease Progression; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Pilot Projects | 2013 |
Anti-hypertensive strategies in patients with MEtabolic parameters, DIabetes mellitus and/or NephropAthy (the M E D I N A study).
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Diabetes Mellitus, Type 2; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Kidney Diseases; Losartan; Male; Metabolic Syndrome; Middle Aged; Risk Factors; Single-Blind Method | 2014 |
Echocardiographic changes and treatment goal rates after a 6-month combined treatment with amlodipine and losartan: a validation study in Andean countries (METAL study).
Topics: Aged; Albuminuria; Amlodipine; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Echocardiography; Female; Follow-Up Studies; Humans; Hypertension; Hyperuricemia; Losartan; Male; Middle Aged; South America; Time Factors; Treatment Outcome | 2013 |
Comparative effectiveness of a fixed-dose combination of losartan + HCTZ versus bisoprolol + HCTZ in patients with moderate-to-severe hypertension: results of the 6-month ELIZA trial.
Topics: Adrenergic beta-1 Receptor Antagonists; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Bisoprolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Calcium Channel Blockers; Chi-Square Distribution; Diuretics; Doxazosin; Drug Combinations; Drug Therapy, Combination; Electrocardiography; Female; Heart Rate; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Pulse Wave Analysis; Severity of Illness Index; Time Factors; Treatment Outcome; Ukraine; Vascular Stiffness | 2013 |
Comparison of the effects of amlodipine and losartan on blood pressure and diurnal variation in hypertensive stroke patients: a prospective, randomized, double-blind, comparative parallel study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Circadian Rhythm; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Stroke; Treatment Outcome | 2013 |
[Possibilities of rational combination antihypertensive therapy: results of HEMERA international clinical trial].
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Diuretics; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Ramipril; Treatment Outcome; Young Adult | 2013 |
Functional vascular study in hypertensive subjects with type 2 diabetes using losartan or amlodipine.
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Cross-Sectional Studies; Diabetes Mellitus, Type 2; Female; Humans; Hypertension; Losartan; Male; Manometry; Middle Aged; Pulse Wave Analysis | 2014 |
Efficacy and tolerability of amlodipine camsylate/losartan 5/100-mg versus losartan/hydrochlorothiazide 100/12.5-mg fixed-dose combination in hypertensive patients nonresponsive to losartan 100-mg monotherapy.
Topics: Adult; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome | 2014 |
Efficacy and safety of fixed-dose losartan/hydrochlorothiazide/amlodipine combination versus losartan/hydrochlorothiazide combination in Japanese patients with essential hypertension.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Combinations; Drug Monitoring; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Hypertension; Japan; Losartan; Male; Middle Aged; Treatment Outcome | 2015 |
Fixed-dose combination of losartan and hydrochlorothiazide significantly improves endothelial function in uncontrolled hypertension by low-dose amlodipine: a randomized study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Brachial Artery; Drug Therapy, Combination; Endothelium, Vascular; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Pulsatile Flow; Treatment Outcome | 2014 |
Losartan reduces insulin resistance by inhibiting oxidative stress and enhancing insulin signaling transduction.
Topics: 3T3-L1 Cells; Adipocytes; Aged; Amlodipine; Animals; Antihypertensive Agents; Diabetic Nephropathies; Humans; Insulin Resistance; Losartan; Male; Mice; Middle Aged; Oxidative Stress; Receptor, Insulin; Signal Transduction | 2015 |
Pharmacogenomics of hypertension: a genome‐wide, placebo‐controlled cross‐over study, using four classes of antihypertensive drugs.
Topics: Adult; Aldehyde Oxidoreductases; Amlodipine; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Bisoprolol; Blood Pressure Monitoring, Ambulatory; Chloride Channels; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Essential Hypertension; Finland; Genome-Wide Association Study; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Membrane Proteins; Meta-Analysis as Topic; Microfilament Proteins; Middle Aged; Mutation, Missense; Pharmacogenetics; Polymorphism, Single Nucleotide; Severity of Illness Index; Tetrazoles; Treatment Outcome | 2015 |
Prospective randomized study of the tolerability and efficacy of combination therapy for hypertensive chronic kidney disease: results of the PROTECT-CKD study.
Topics: Adult; Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Diuretics; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension, Renal; Losartan; Male; Middle Aged; Prospective Studies; Renal Insufficiency, Chronic; Young Adult | 2015 |
[Effectiveness and safety of losartan and its combination with amlodipine in therapy of arterial hypertension].
Topics: Aged; Amlodipine; Antihypertensive Agents; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome | 2013 |
Add-on effect of hydrochlorothiazide 12.5 mg in Japanese subjects with essential hypertension uncontrolled with losartan 50 mg and amlodipine 5 mg.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Hypertension; Japan; Losartan; Male; Middle Aged; Single-Blind Method; Treatment Outcome; Young Adult | 2015 |
Visit-to-visit variability and seasonal variation in blood pressure: Combination of Antihypertensive Therapy in the Elderly, Multicenter Investigation (CAMUI) Trial subanalysis.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Prospective Studies; Seasons; Treatment Outcome | 2015 |
Renin-Angiotensin System Blockade Associated with Statin Improves Endothelial Function in Diabetics.
Topics: Amino Acids; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Benzazepines; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Brachial Artery; Diabetes Mellitus, Type 2; Endothelium, Vascular; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Pulse Wave Analysis; Renin-Angiotensin System; Statistics, Nonparametric; Time Factors; Treatment Outcome; Vascular Stiffness | 2015 |
Effect of Diuretic or Calcium-Channel Blocker Plus Angiotensin-Receptor Blocker on Diastolic Function in Hypertensive Patients.
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Angiotensin Receptor Antagonists; Blood Pressure; Calcium Channel Blockers; Diastole; Diuretics; Drug Therapy, Combination; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Ventricular Dysfunction, Left | 2016 |
Effect of losartan combined with amlodipine or with a thiazide on uric acid levels in hypertensive patients.
Topics: Amlodipine; Antihypertensive Agents; Biomarkers; Blood Pressure; Dose-Response Relationship, Drug; Drug Combinations; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Time Factors; Treatment Outcome; Uric Acid | 2017 |
The effects of missed doses of amlodipine and losartan on blood pressure in older hypertensive patients.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Double-Blind Method; Female; Humans; Hypertension; Losartan; Male; Treatment Outcome | 2017 |
Comparison of Fixed-dose Combinations of Amlodipine/Losartan Potassium/Chlorthalidone and Amlodipine/Losartan Potassium in Patients With Stage 2 Hypertension Inadequately Controlled With Amlodipine/Losartan Potassium: A Randomized, Double-blind, Multicent
Topics: Adult; Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Combinations; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome; Young Adult | 2017 |
A Randomized, Multicenter, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and the Tolerability of a Triple Combination of Amlodipine/Losartan/Rosuvastatin in Patients With Comorbid Essential Hypertension and Hyperlipidemia.
Topics: Aged; Amlodipine; Anticholesteremic Agents; Antihypertensive Agents; Blood Pressure; Comorbidity; Double-Blind Method; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hypercholesterolemia; Losartan; Male; Middle Aged; Risk Factors; Rosuvastatin Calcium; Treatment Outcome | 2017 |
Combination Therapy Is Superior to Sequential Monotherapy for the Initial Treatment of Hypertension: A Double-Blind Randomized Controlled Trial.
Topics: Adolescent; Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Dose-Response Relationship, Drug; Double-Blind Method; Doxazosin; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome; Young Adult | 2017 |
Comparison of 24-Hour Ambulatory Central Blood Pressure Reduction Efficacy Between Fixed Amlodipine or Up-Titrated Hydrochlorothiazide Plus Losartan: The K-Central Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Double-Blind Method; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Prospective Studies; Republic of Korea; Time Factors; Treatment Outcome | 2019 |
The association of smoothness index of central blood pressure with ambulatory carotid femoral pulse wave velocity after 20-week treatment with losartan in combination with amlodipine versus hydrochlorothiazide.
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Carotid-Femoral Pulse Wave Velocity; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged | 2019 |
Polypill for Cardiovascular Disease Prevention in an Underserved Population.
Topics: Adult; Alabama; Amlodipine; Antihypertensive Agents; Atorvastatin; Cholesterol, LDL; Community Health Centers; Drug Combinations; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypercholesterolemia; Hypertension; Losartan; Male; Medically Underserved Area; Medication Adherence; Middle Aged | 2019 |
Comparison of Pharmacokinetics of a Fixed-Dose Combination of Amlodipine/Losartan/Rosuvastatin with Concomitant Administration of Amlodipine/Losartan and Rosuvastatin in Healthy Volunteers.
Topics: Administration, Oral; Adult; Amlodipine; Cross-Over Studies; Dose-Response Relationship, Drug; Drug Combinations; Drug Compounding; Healthy Volunteers; Humans; Losartan; Male; Middle Aged; Rosuvastatin Calcium; Tablets | 2020 |
Comparison of Blood Pressure Variability Between Losartan and Amlodipine in Essential Hypertension (COMPAS-BPV).
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Drug Therapy, Combination; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Losartan; Male; Middle Aged | 2020 |
Low-Dose Triple Antihypertensive Combination Therapy in Patients with Hypertension: A Randomized, Double-Blind, Phase II Study.
Topics: Aged; Amlodipine; Antihypertensive Agents; Chlorthalidone; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Hypertension; Losartan; Male; Middle Aged | 2020 |
Comparison of losartan and amlodipine effects on the outcomes of patient with COVID-19 and primary hypertension: A randomised clinical trial.
Topics: Aged; Aged, 80 and over; Amlodipine; Antihypertensive Agents; Blood Pressure; COVID-19; Double-Blind Method; Humans; Hypertension; Losartan; Middle Aged; SARS-CoV-2; Treatment Outcome | 2021 |
Pharmacokinetics of a Fixed-Dose Combination of Amlodipine/Losartan and Chlorthalidone Compared to Concurrent Administration of the Separate Components.
Topics: Amlodipine; Chlorthalidone; Cross-Over Studies; Drug Combinations; Humans; Losartan | 2022 |
The EffecTs of Amlodipine and other Blood PREssure Lowering Agents on Microvascular FuncTion in Small Vessel Diseases (TREAT-SVDs) trial: Study protocol for a randomised crossover trial.
Topics: Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Cross-Over Studies; Humans; Losartan; Prospective Studies; Randomized Controlled Trials as Topic | 2023 |
Comparison of efficacy and safety between third-dose triple and third-dose dual antihypertensive combination therapies in patients with hypertension.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Chlorthalidone; Double-Blind Method; Drug Therapy, Combination; Humans; Hypertension; Hypotension; Losartan; Treatment Outcome | 2023 |
A Randomized, Multicenter, Double-blind, Placebo-Controlled Study to Evaluate the Efficacy and Safety of a Quadruple Combination of Amlodipine, Losartan, Rosuvastatin, and Ezetimibe in Patients with Concomitant Essential Hypertension and Dyslipidemia.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Cholesterol, LDL; Double-Blind Method; Dyslipidemias; Essential Hypertension; Ezetimibe; Humans; Hypertension; Losartan; Rosuvastatin Calcium; Treatment Outcome | 2023 |
67 other study(ies) available for losartan and amlodipine
| Article | Year |
|---|---|
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship | 2010 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Preclinical strategy to reduce clinical hepatotoxicity using in vitro bioactivation data for >200 compounds.
Topics: Chemical and Drug Induced Liver Injury; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Decision Trees; Drug Evaluation, Preclinical; Drug-Related Side Effects and Adverse Reactions; Glutathione; Humans; Liver; Pharmaceutical Preparations; Protein Binding | 2012 |
Mitigating the inhibition of human bile salt export pump by drugs: opportunities provided by physicochemical property modulation, in silico modeling, and structural modification.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Bile Acids and Salts; Cell Line; Chemical and Drug Induced Liver Injury; Humans; Quantitative Structure-Activity Relationship | 2012 |
Protection of the arterial internal elastic lamina by inhibition of the renin-angiotensin system in the rat.
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Angiotensinogen; Animals; Aorta, Abdominal; Aorta, Thoracic; Aortic Rupture; Benzimidazoles; Blood Pressure; Body Weight; Calcium Channel Blockers; Collagen; Elastic Tissue; Elastin; Enalapril; Heart; Heart Rate; Losartan; Male; Mibefradil; Muscle, Smooth, Vascular; Organ Size; Peptidyl-Dipeptidase A; Rats; Rats, Inbred BN; Renin; Renin-Angiotensin System; Tetrahydronaphthalenes | 1998 |
Randomized clinical trials of antihypertensive drugs: all that glitters is not gold.
Topics: Amlodipine; Antihypertensive Agents; Bias; Canada; Evidence-Based Medicine; Humans; Losartan; Randomized Controlled Trials as Topic; Reproducibility of Results; Research Design; Treatment Outcome | 1998 |
Key features of candesartan cilexetil and a comparison with other angiotensin II receptor antagonists.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Delayed-Action Preparations; Diuretics; Dose-Response Relationship, Drug; Drug Therapy, Combination; Humans; Hydrochlorothiazide; Hypertension; Losartan; Renin-Angiotensin System; Retrospective Studies; Sodium Chloride Symporter Inhibitors; Tetrazoles; Treatment Outcome | 1999 |
[Arterial hypertension and systolic left ventricular dysfunction: therapeutic approach].
Topics: Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Carbazoles; Carvedilol; Clinical Trials as Topic; Databases, Bibliographic; Felodipine; Heart Failure; Humans; Hypertension; Hypertrophy, Left Ventricular; Losartan; Meta-Analysis as Topic; Propanolamines; Randomized Controlled Trials as Topic; Risk Factors; Systole; Vasodilator Agents; Ventricular Dysfunction, Left | 1999 |
Diverse effects of chronic treatment with losartan, fosinopril, and amlodipine on apoptosis, angiotensin II in the left ventricle of hypertensive rats.
Topics: Amlodipine; Angiotensin II; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Apoptosis; Blood Pressure; China; Disease Models, Animal; Fosinopril; Heart Ventricles; Hypertrophy, Left Ventricular; Losartan; Models, Cardiovascular; Myocardium; Random Allocation; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1 | 2001 |
[Comparative effects of losartan and amlodipine on activities of sympathetic nerve, renin-angiotensin-aldosterone system and brain natriuretic peptide in the elderly hypertensive patients].
Topics: Aged; Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Heart Rate; Humans; Hypertension; Losartan; Natriuretic Peptide, Brain; Renin-Angiotensin System; Sympathetic Nervous System | 2002 |
Targeting the atherosclerotic process in clinical practice. A new look at established agents.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Calcium Channel Blockers; Coronary Artery Disease; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Risk Factors | 2002 |
Differential effects of antihypertensive drug therapy on arterial compliance.
Topics: Adrenergic beta-Antagonists; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Atenolol; Blood Pressure; Calcium Channel Blockers; Enalapril; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Treatment Outcome; Vascular Resistance | 2002 |
[Contrast of losartan, fosinopril and amlodipine on cardiomyocyte apoptosis and left ventricular remolding in hypertensive rats].
Topics: Amlodipine; Animals; Antihypertensive Agents; Apoptosis; Cardiotonic Agents; Female; Fosinopril; Hypertension; Losartan; Male; Myocytes, Cardiac; Random Allocation; Rats; Rats, Inbred SHR; Ventricular Remodeling | 2001 |
Anti-proteinuric effect of losartan: statistical vs clinical significance.
Topics: Amlodipine; Antihypertensive Agents; Data Interpretation, Statistical; Humans; Losartan; Proteinuria; Treatment Outcome | 2004 |
Doxorubicine-congestive heart failure-increased big endothelin-1 plasma concentration: reversal by amlodipine, losartan, and gastric pentadecapeptide BPC157 in rat and mouse.
Topics: Amlodipine; Animals; Doxorubicin; Endothelin-1; Gastric Mucosa; Heart Failure; Losartan; Male; Mice; Peptide Fragments; Peptides; Proteins; Rats; Rats, Wistar; Stomach | 2004 |
Valsartan treatment of hypertension--does VALUE add value?
Topics: Aged; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Benzimidazoles; Biphenyl Compounds; Blood Pressure; Calcium Channel Blockers; Endpoint Determination; Humans; Hypertension; Losartan; Randomized Controlled Trials as Topic; Risk Factors; Tetrazoles; Valine; Valsartan | 2004 |
Evaluation of a technique of inducing hypertensive renal insufficiency in cats.
Topics: Amlodipine; Analysis of Variance; Animals; Blood Pressure; Blood Pressure Determination; Cat Diseases; Cats; Diltiazem; Enalapril; Heart Rate; Hypertension, Renal; Infarction; Kidney; Ligation; Losartan; Nephrectomy; Renal Insufficiency; Telemetry; Time Factors | 2004 |
[Characteristics of hypotensive effect in patients with arterial hypertension and desaturation signs of obstructive sleep apnea syndrome during sleep].
Topics: Adult; Aged; Amlodipine; Antihypertensive Agents; Blood Gas Monitoring, Transcutaneous; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Female; Humans; Hypertension; Losartan; Male; Middle Aged; Sleep; Sleep Apnea, Obstructive; Treatment Outcome | 2004 |
Adult hypertension: reducing cardiovascular morbidity and mortality.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Aged; Aged, 80 and over; Alcohol Drinking; Amlodipine; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Blood Pressure Determination; Calcium Channel Blockers; Cardiovascular Diseases; Diabetes Complications; Diltiazem; Diuretics; Drug Evaluation; Health Behavior; Humans; Hypertension; Losartan; Obesity; Renal Insufficiency; Sodium; Stroke; Verapamil | 2005 |
TGF-beta and TNF-alpha producing effects of losartan and amlodipine on human mononuclear cell culture.
Topics: Amlodipine; Antihypertensive Agents; Atherosclerosis; Cells, Cultured; Humans; Leukocytes, Mononuclear; Losartan; Transforming Growth Factor beta; Tumor Necrosis Factor-alpha | 2005 |
[Pharmacogenetics of angiotensin system in non diabetic nephropathy].
Topics: Adult; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Chronic Disease; Data Interpretation, Statistical; Female; Genotype; Glomerulonephritis; Humans; Kidney Diseases; Losartan; Male; Middle Aged; Pharmacogenetics; Polymorphism, Genetic; Proteinuria | 2005 |
Renal mitochondrial dysfunction in spontaneously hypertensive rats is attenuated by losartan but not by amlodipine.
Topics: Actins; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Blood Pressure; Calcium Channel Blockers; Electron Transport Complex IV; Glomerular Mesangium; Glutathione; Hydrogen Peroxide; Hypertension; Ion Channels; Kidney; Losartan; Male; Membrane Potentials; Membrane Transport Proteins; Mitochondria; Mitochondrial Proteins; NADH Dehydrogenase; Nitric Oxide Synthase; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Superoxide Dismutase; Uncoupling Protein 2 | 2006 |
Arteriolar remodeling in essential hypertension: are connective tissue growth factor and transforming growth factor involved?
Topics: Amlodipine; Antihypertensive Agents; Arterioles; Connective Tissue Growth Factor; Humans; Hypertension; Immediate-Early Proteins; Intercellular Signaling Peptides and Proteins; Losartan; Transforming Growth Factor beta | 2006 |
Antihypertensive agents have different ability to modulate arterial pressure and heart rate variability in 2K1C rats.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Atenolol; Autonomic Nervous System; Blood Pressure; Cardiovascular System; Heart Rate; Hydrochlorothiazide; Hypertension; Losartan; Male; Ramipril; Rats; Rats, Wistar; Sympathetic Nervous System | 2006 |
Pulsology reloaded: commentary on similar effects of treatment on central and brachial blood pressure in older hypertensive subjects.
Topics: Aged; Aged, 80 and over; Aging; Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Brachial Artery; Enalapril; Humans; Hydrochlorothiazide; Hypertension; Losartan; Manometry; Perindopril; Ultrasonography, Doppler | 2007 |
Sudden cardiac standstill during skin flap elevation in a patient undergoing craniotomy.
Topics: Aged; Amlodipine; Anesthesia, General; Anti-Arrhythmia Agents; Antihypertensive Agents; Atropine; Blood Pressure; Bradycardia; Brain Neoplasms; Calcium Channel Blockers; Craniotomy; Dermatologic Surgical Procedures; Female; Heart Arrest; Heart Rate; Humans; Hypertension; Losartan; Reflex, Abnormal; Skin; Surgical Flaps; Trigeminal Nerve | 2007 |
Renal mitochondrial impairment is attenuated by AT1 blockade in experimental Type I diabetes.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Antioxidants; Blood Glucose; Blood Pressure; Diabetes Mellitus, Experimental; Diabetes Mellitus, Type 1; Electron Transport Complex IV; Glutathione; Hydrogen Peroxide; Ion Channels; Kidney; Losartan; Male; Membrane Potential, Mitochondrial; Mitochondria; Mitochondrial Proteins; Nitric Oxide Synthase; Pyruvic Acid; Rats; Rats, Sprague-Dawley; Reactive Oxygen Species; Receptor, Angiotensin, Type 1; Uncoupling Protein 2 | 2008 |
Application in the STRATHE trial of a score system to compare the efficacy and the tolerability of different therapeutic strategies in the management of hypertension.
Topics: Amlodipine; Antihypertensive Agents; Atenolol; Double-Blind Method; Drug Therapy, Combination; France; Humans; Hydrochlorothiazide; Hypertension; Indapamide; Losartan; Perindopril; Randomized Controlled Trials as Topic; Tetrazoles; Treatment Outcome; Valine; Valsartan | 2008 |
Beneficial effects of the combination of amlodipine and losartan for lowering blood pressure in spontaneously hypertensive rats.
Topics: Acetylcholine; Administration, Oral; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Aorta; Blood Pressure; Body Weight; Calcium Channel Blockers; Cardiomegaly; Collagen; Disease Models, Animal; Drug Therapy, Combination; Hypertension; Losartan; Myocardium; Rats; Rats, Inbred SHR; Time Factors; Vasodilation; Vasodilator Agents | 2009 |
Simultaneous spectrophotometric determination of losartan potassium, amlodipine besilate and hydrochlorothiazide in pharmaceuticals by chemometric methods.
Topics: Amlodipine; Chemistry, Pharmaceutical; Hydrochlorothiazide; Least-Squares Analysis; Linear Models; Losartan; Multivariate Analysis; Principal Component Analysis; Spectrophotometry, Ultraviolet; Tablets | 2010 |
Anti-inflammatory effects of anti-hypertensive agents: influence on interleukin-1β secretion by peripheral blood polymorphonuclear leukocytes from patients with essential hypertension.
Topics: Adult; Amlodipine; Anti-Inflammatory Agents, Non-Steroidal; Antihypertensive Agents; Atenolol; Captopril; Case-Control Studies; Female; Humans; Hydrochlorothiazide; Hypertension; In Vitro Techniques; Inflammation Mediators; Interleukin-1beta; Lipopolysaccharides; Losartan; Male; Middle Aged; Neutrophils | 2011 |
Scintigraphic diagnosis of Erdheim-Chester disease.
Topics: Aged; Amlodipine; Antihypertensive Agents; Diabetes Mellitus, Type 2; Drug Combinations; Erdheim-Chester Disease; Gated Blood-Pool Imaging; Humans; Hydrochlorothiazide; Hypoglycemic Agents; Hypolipidemic Agents; Imidazoles; Knee Joint; Losartan; Male; Metformin; Positron-Emission Tomography; Prostatic Neoplasms; Simvastatin | 2011 |
Tube feeding and drugs in intensive care unit.
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Critical Care; Delayed-Action Preparations; Drug Combinations; Drug Delivery Systems; Drug-Related Side Effects and Adverse Reactions; Enteral Nutrition; Female; Humans; Intensive Care Units; Intubation, Gastrointestinal; Losartan; Pharmaceutical Preparations | 2011 |
STK39 variation predicts the ambulatory blood pressure response to losartan in hypertensive men.
Topics: Adult; Alleles; Amlodipine; Antihypertensive Agents; Bisoprolol; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Genotype; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Polymorphism, Single Nucleotide; Protein Serine-Threonine Kinases | 2012 |
An economic evaluation of antihypertensive therapies based on clinical trials.
Topics: Amlodipine; Antihypertensive Agents; Atenolol; Blood Pressure; Drug Costs; Drug Therapy, Combination; Enalapril; Female; Humans; Hydrochlorothiazide; Hypertension; Losartan; Male; Middle Aged; Randomized Controlled Trials as Topic | 2012 |
Impaired sodium excretion and salt-sensitive hypertension in corin-deficient mice.
Topics: Aldosterone; Amiloride; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Biomarkers; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Body Weight; Calcium Channel Blockers; Disease Models, Animal; Dose-Response Relationship, Drug; Homeostasis; Hypertension; Kidney; Losartan; Male; Mice; Mice, Knockout; Natriuresis; Renin; Serine Endopeptidases; Sodium Channel Blockers; Sodium Chloride, Dietary; Telemetry; Time Factors | 2012 |
Transient prehypertensive treatment in spontaneously hypertensive rats: a comparison of losartan and amlodipine regarding long-term blood pressure, cardiac and renal protection.
Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Antihypertensive Agents; Blood Pressure; Cardiotonic Agents; Collagen; Gene Expression Regulation; Heart Ventricles; Hypertension; Hypertrophy, Left Ventricular; Kidney; Losartan; Male; Natriuretic Peptide, Brain; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Renin-Angiotensin System; Stroke Volume; Transforming Growth Factor beta1; Ultrasonography | 2012 |
Differential effects of antihypertensive treatments on apoptosis, oxidative stress, and expression of angiotensin receptors in the cerebral cortex from the onset of prehypertension and hypertension in stroke-prone spontaneous hypertensive rats.
Topics: Amlodipine; Animals; Antihypertensive Agents; Apoptosis; Blotting, Western; Cerebral Cortex; Hypertension; Losartan; Male; Oxidative Stress; Prehypertension; Radioimmunoassay; Rats; Rats, Inbred SHR; Rats, Inbred WKY; Receptors, Angiotensin | 2013 |
The influence of food on the pharmacokinetics of amlodipine and losartan after single-dose of its compound tablets in healthy chinese subjects.
Topics: Administration, Oral; Adult; Amlodipine; Area Under Curve; Asian People; Female; Food; Food-Drug Interactions; Humans; Imidazoles; Losartan; Male; Tablets; Tetrazoles; Young Adult | 2014 |
Long-term prehypertension treatment with losartan effectively prevents brain damage and stroke in stroke-prone spontaneously hypertensive rats.
Topics: Aldosterone; Amlodipine; Angiotensin II; Animals; Apoptosis; Blood Pressure; Brain; Hypertension; Losartan; Male; Membrane Glycoproteins; NADPH Oxidase 2; NADPH Oxidases; Oxidative Stress; Prehypertension; Rats; Rats, Inbred SHR; Renin-Angiotensin System; Stroke; Superoxide Dismutase; Time Factors | 2014 |
Prehypertensive treatment with losartan, however not amlodipine, leads to long-term effects on blood pressure and reduces the risk of stroke in spontaneously hypertensive stroke-prone rats.
Topics: Amlodipine; Animals; Blood Pressure; Gene Expression Regulation; Humans; Hypertension; Losartan; Male; Oxidative Stress; Rats; Rats, Inbred SHR; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Risk Factors; Stroke | 2016 |
Cost-benefit analysis of the polypill in the primary prevention of myocardial infarction and stroke.
Topics: Aged; Aged, 80 and over; Amlodipine; Aspirin; Cardiovascular Agents; Case-Control Studies; Cohort Studies; Cost-Benefit Analysis; Humans; Hydrochlorothiazide; Losartan; Markov Chains; Middle Aged; Myocardial Infarction; Polypharmacy; Primary Prevention; Quality-Adjusted Life Years; Simvastatin; Stroke; United Kingdom | 2016 |
Losartan and amlodipine overdose-Case Report of a patient with anuric renal failure prior to the onset of hypotension.
Topics: Acute Kidney Injury; Amlodipine; Antihypertensive Agents; Anuria; Drug Overdose; Female; Humans; Hypotension; Losartan; Middle Aged | 2016 |
Prediction of drug interaction between oral adsorbent AST-120 and concomitant drugs based on the in vitro dissolution and in vivo absorption behavior of the drugs.
Topics: Administration, Oral; Adsorption; Aluminum Hydroxide; Amlodipine; Aspirin; Carbon; Drug Interactions; Glycine; Humans; Intestinal Absorption; Losartan; Magnesium; Metoprolol; Models, Biological; Nifedipine; Oxides; Renal Insufficiency, Chronic; Solubility; Triazolam | 2016 |
Comparisons of the pharmacokinetics and tolerability of fixed-dose combinations of amlodipine besylate/losartan and amlodipine camsylate/losartan in healthy subjects: a randomized, open-label, single-dose, two-period, two-sequence crossover study.
Topics: Administration, Oral; Amlodipine; Angiotensin II Type 1 Receptor Blockers; Antihypertensive Agents; Calcium Channel Blockers; Dose-Response Relationship, Drug; Half-Life; Healthy Volunteers; Humans; Losartan | 2016 |
Molecular insight into atypical instability behavior of fixed-dose combination containing amlodipine besylate and losartan potassium.
Topics: Amlodipine; Chromatography, High Pressure Liquid; Drug Combinations; Drug Compounding; Drug Interactions; Drug Stability; Hydrogen-Ion Concentration; Losartan; Magnetic Resonance Spectroscopy; Mass Spectrometry; Molecular Structure | 2017 |
Cost-effectiveness of the polypill versus risk assessment for prevention of cardiovascular disease.
Topics: Administration, Oral; Adult; Aged; Amlodipine; Antihypertensive Agents; Cardiovascular Diseases; Computer Simulation; Cost-Benefit Analysis; Drug Combinations; Drug Costs; Dyslipidemias; Female; Humans; Hydrochlorothiazide; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hypertension; Losartan; Male; Middle Aged; Models, Economic; Primary Prevention; Quality-Adjusted Life Years; Risk Assessment; Risk Factors; Simvastatin; Tablets; Time Factors; Treatment Outcome | 2017 |
Inhibition of the Renin-Angiotensin System Post Myocardial Infarction Prevents Inflammation-Associated Acute Cardiac Rupture.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Inflammatory Agents; Antihypertensive Agents; Blood Pressure; Calcium Channel Blockers; Chemotaxis, Leukocyte; Cytokines; Disease Models, Animal; Dose-Response Relationship, Drug; Heart Rupture, Post-Infarction; Inflammation; Inflammation Mediators; Losartan; Male; Mice, 129 Strain; Monocytes; Myocardial Infarction; Myocardium; Neutrophil Infiltration; Neutrophils; Perindopril; Renin-Angiotensin System; Spleen; Time Factors | 2017 |
[The Effectiveness of Combination Antihypertensive Therapy in Women With Hypothyroidism and the Metabolic Syndrome].
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Dihydropyridines; Drug Therapy, Combination; Female; Heart Rate; Humans; Hypertension; Hypothyroidism; Imidazoles; Losartan; Metabolic Syndrome; Middle Aged | 2016 |
Influence of antihypertensive drugs on aortic and coronary effects of Ang-(1-7) in pressure-overloaded rats.
Topics: Amlodipine; Angiotensin I; Angiotensin II Type 1 Receptor Blockers; Angiotensin-Converting Enzyme Inhibitors; Animals; Antihypertensive Agents; Aorta, Abdominal; Blood Pressure; Calcium Channel Blockers; Captopril; Coronary Vessels; Losartan; Male; Mineralocorticoid Receptor Antagonists; Models, Animal; Peptide Fragments; Rats, Wistar; Reproducibility of Results; Spironolactone; Time Factors; Vasoconstriction; Vasodilation | 2017 |
Endothelial transcriptomics reveals activation of fibrosis-related pathways in hypertension.
Topics: Amlodipine; Animals; Blood Pressure; Calcium Channel Blockers; Disease Models, Animal; Fibrosis; Heart Rate; Hypertension; Losartan; Male; Mice | 2018 |
Alternatives to specific uric acid lowering treatment in gout in patients with cardiovascular disease.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Atorvastatin; Calcium Channel Blockers; Cardiovascular Diseases; Clopidogrel; Gout; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Losartan; Purinergic P2Y Receptor Antagonists; Risk Factors; Uric Acid | 2018 |
Effects of Different Antihypertensive Drug Combinations on Blood Pressure and Arterial Stiffness.
Topics: Aged; Amlodipine; Antihypertensive Agents; Arteries; Blood Pressure; Diastole; Drug Combinations; Essential Hypertension; Female; Humans; Hydrochlorothiazide; Lisinopril; Losartan; Male; Middle Aged; Prospective Studies; Pulse Wave Analysis; Systole; Valsartan; Vascular Resistance; Vascular Stiffness | 2019 |
The smoothness index: an 'all purposes' approach to the assessment of the homogeneity of 24-h blood pressure control?
Topics: Amlodipine; Antihypertensive Agents; Blood Pressure; Blood Pressure Monitoring, Ambulatory; Hydrochlorothiazide; Losartan; Pulse Wave Analysis | 2019 |
Detection of significant left renal artery stenosis caused by fibromuscular dysplasia with selective angiography.
Topics: Amlodipine; Angioplasty, Balloon; Antihypertensive Agents; Computed Tomography Angiography; Drug Combinations; Female; Fibromuscular Dysplasia; Headache; Humans; Hypertension; Losartan; Renal Artery Obstruction; Young Adult | 2020 |
Oral Manifestations of Commonly Prescribed Drugs.
Topics: Albuterol; Amlodipine; Anticonvulsants; Antihypertensive Agents; Atorvastatin; Bisphosphonate-Associated Osteonecrosis of the Jaw; Bronchodilator Agents; Deprescriptions; Drug Hypersensitivity; Fluorides; Gingival Overgrowth; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Hyperpigmentation; Hypoglycemic Agents; Lisinopril; Losartan; Metformin; Metoprolol; Mouth Diseases; Omeprazole; Oral Hygiene; Proton Pump Inhibitors; Simvastatin; Thyroxine; Toothpastes; Xerostomia | 2020 |
More Than Meets the Eye: A Patient with Hand Swelling and Newly Diagnosed Diabetes Mellitus.
Topics: Aged; Amlodipine; Anemia; Antihypertensive Agents; Blood Sedimentation; C-Reactive Protein; Diabetes Mellitus, Type 2; Edema; Glucocorticoids; Hand; Humans; Hypertension; Hypoglycemic Agents; Losartan; Male; Metformin; Prednisolone; Rotator Cuff Injuries; Syndrome; Synovitis | 2021 |
Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel disease.
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Animals; Antihypertensive Agents; Cerebral Small Vessel Diseases; Cerebrovascular Circulation; Dementia, Vascular; Disease Models, Animal; Drug Therapy, Combination; Eplerenone; Heart Disease Risk Factors; Humans; Hyperemia; Hypertension; Losartan; Male; Mice; Microvessels; Potassium Channels, Inwardly Rectifying; Renin-Angiotensin System | 2021 |
Clinical effectiveness and safety of amlodipine/losartan-based single-pill combination therapy in patients with hypertension: Findings from real-world, multicenter observational databases.
Topics: Amlodipine; Antihypertensive Agents; Humans; Hypertension; Losartan; Treatment Outcome; Uric Acid | 2021 |
Dose-dependent atorvastatin associated with angioedema.
Topics: Aged; Amlodipine; Angioedema; Antihypertensive Agents; Atorvastatin; Calcium Channel Blockers; Female; Humans; Hypertension; Losartan | 2022 |
Comment on 'Comparison of losartan and amlodipine effects on the outcomes of patient with COVID-19 and primary hypertension: A randomised clinical trial'.
Topics: Amlodipine; Antihypertensive Agents; COVID-19; Humans; Hypertension; Losartan; SARS-CoV-2 | 2021 |
Antihypertensive medicine use differs between Ghana and Nigeria.
Topics: Amlodipine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antihypertensive Agents; Calcium Channel Blockers; Ghana; Humans; Hypertension; Lisinopril; Losartan; Nifedipine; Nigeria | 2022 |
IR microspectroscopic investigation of the interaction of some losartan salts with human stratum corneum protein and its effect on losartan transdermal permeation.
Topics: Amlodipine; Humans; Keratins; Leukemia, Myeloid, Acute; Losartan; Pharmaceutical Preparations; Salts; Skin | 2023 |
NITROSOGENESIS OF SKIN CANCER: THE NITROSAMINE CONTAMINATION IN THE CALCIUM CHANNEL BLOCKERS (AMLODIPINE), BETA BLOCKERS (BISOPROLOL), SARTANS (VALSARTAN/LOSARTAN), ACE INHIBITORS (PERINDOPRIL/ENALAPRIL), TRICYCLIC ANTIDEPRESSANTS (MELITRACEN), SSRIS (PAR
Topics: Amlodipine; Angiotensin II Type 1 Receptor Blockers; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Antidepressive Agents, Tricyclic; Bisoprolol; Calcium Channel Blockers; Enalapril; Humans; Incidence; Losartan; Metformin; Paroxetine; Perindopril; Selective Serotonin Reuptake Inhibitors; Serotonin and Noradrenaline Reuptake Inhibitors; Skin Neoplasms; Valsartan; Venlafaxine Hydrochloride | 2023 |