Compounds > losartan

losartan and alpha-naphthoflavone

losartan has been researched along with alpha-naphthoflavone in 4 studies

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (25.00)18.2507
2000's3 (75.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Guengerich, FP; Jeong, HG; Lee, H; Lee, HS; Rho, JK; Yun, CH1
Baillie, TA; Cui, D; Dai, R; Korzekwa, KR; Rushmore, TH; Shou, M1
Shou, M1

Reviews

1 review(s) available for losartan and alpha-naphthoflavone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000

Other Studies

3 other study(ies) available for losartan and alpha-naphthoflavone

ArticleYear
Oxidation of the angiotensin II receptor antagonist losartan (DuP 753) in human liver microsomes. Role of cytochrome P4503A(4) in formation of the active metabolite EXP3174.
    Drug metabolism and disposition: the biological fate of chemicals, 1995, Volume: 23, Issue:2

    Topics: Angiotensin II; Angiotensin Receptor Antagonists; Antihypertensive Agents; Benzoflavones; Biotransformation; Biphenyl Compounds; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Humans; Imidazoles; Losartan; Microsomes, Liver; Mixed Function Oxygenases; Oxidation-Reduction; Receptors, Angiotensin; Tetrazoles

1995
A kinetic model for the metabolic interaction of two substrates at the active site of cytochrome P450 3A4.
    The Journal of biological chemistry, 2001, Jan-19, Volume: 276, Issue:3

    Topics: Benzoflavones; Binding Sites; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Kinetics; Losartan; Mixed Function Oxygenases; Models, Biological; Substrate Specificity

2001
Kinetic analysis for multiple substrate interaction at the active site of cytochrome P450.
    Methods in enzymology, 2002, Volume: 357

    Topics: Benzoflavones; Binding Sites; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme Inhibitors; Cytochrome P-450 Enzyme System; Diazepam; Diclofenac; Enzyme Activation; Enzyme Inhibitors; Kinetics; Losartan; Models, Biological; Protein Binding; Quinidine; Recombinant Proteins

2002