losartan and adenosine

losartan has been researched along with adenosine in 14 studies

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (42.86)18.2507
2000's4 (28.57)29.6817
2010's4 (28.57)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Fisk, L; Greene, N; Naven, RT; Note, RR; Patel, ML; Pelletier, DJ1
Ekins, S; Williams, AJ; Xu, JJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cano, C; Malik, KU; Slavik, KJ1
Jackson, EK; Munger, KA1
Barrett, RJ; Droppleman, DA1
Cox, BF; Kitzen, JM; Perrone, MH; Smits, GJ1
Barbant, SD; Chatterjee, K; Gupta, M; MacGregor, JS; Redberg, R; Sudhir, K; Yock, PG1
Abramson, BL; Ando, Si; Brooks, SC; Floras, JS; Rongen, GA1
Clanachan, AS; Dyck, JR; Ford, WR; Jugdutt, BI; Kumar, D; Lopaschuk, GD; Xu, Y1
Hein, TW; Kuo, L; Wang, W; Zhang, C1
Chen, H; McClure, JM; O'Leary, DS; Rossi, NF; Scislo, TJ1

Reviews

1 review(s) available for losartan and adenosine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for losartan and adenosine

ArticleYear
Angiotensin AT1 receptor blockade abolishes the reflex sympatho-excitatory response to adenosine.
    The Journal of clinical investigation, 1998, Feb-15, Volume: 101, Issue:4

    Topics: Adenosine; Adrenergic beta-Antagonists; Adult; Angiotensin Receptor Antagonists; Cross-Over Studies; Double-Blind Method; Hemodynamics; Humans; Losartan; Male; Nitroprusside; Norepinephrine; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Sympathetic Nervous System

1998

Other Studies

12 other study(ies) available for losartan and adenosine

ArticleYear
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Developing structure-activity relationships for the prediction of hepatotoxicity.
    Chemical research in toxicology, 2010, Jul-19, Volume: 23, Issue:7

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Humans; Structure-Activity Relationship; Tetracyclines; Thiophenes

2010
A predictive ligand-based Bayesian model for human drug-induced liver injury.
    Drug metabolism and disposition: the biological fate of chemicals, 2010, Volume: 38, Issue:12

    Topics: Bayes Theorem; Chemical and Drug Induced Liver Injury; Humans; Ligands

2010
Loss of adenosine-induced negative inotropic effect in hyperexcited rabbit hearts: relationship to PKC.
    The American journal of physiology, 1995, Volume: 268, Issue:3 Pt 2

    Topics: Acetylcholine; Adenosine; Angiotensin II; Animals; Behavior, Animal; Biphenyl Compounds; Blood Pressure; Depression, Chemical; Enzyme Activation; Heart Rate; Imidazoles; In Vitro Techniques; Losartan; Male; Myocardial Contraction; Naphthalenes; Norepinephrine; Perfusion; Phentolamine; Phorbol 12,13-Dibutyrate; Polycyclic Compounds; Propranolol; Protein Kinase C; Rabbits; Tetradecanoylphorbol Acetate; Tetrazoles

1995
Effects of selective A1 receptor blockade on glomerular hemodynamics: involvement of renin-angiotensin system.
    The American journal of physiology, 1994, Volume: 267, Issue:5 Pt 2

    Topics: Adenosine; Analysis of Variance; Angiotensin II; Animals; Arterioles; Biphenyl Compounds; Blood Pressure; Capillaries; Glomerular Filtration Rate; Hematocrit; Hemodynamics; Imidazoles; Kidney Glomerulus; Losartan; Models, Cardiovascular; Muscle, Smooth, Vascular; Purinergic P1 Receptor Antagonists; Rats; Rats, Wistar; Receptors, Purinergic P1; Reference Values; Regional Blood Flow; Renal Circulation; Renin-Angiotensin System; Tetrazoles; Vascular Resistance; Xanthines

1994
Interactions of adenosine A1 receptor-mediated renal vasoconstriction with endogenous nitric oxide and ANG II.
    The American journal of physiology, 1993, Volume: 265, Issue:5 Pt 2

    Topics: Adenine; Adenosine; Angiotensin II; Animals; Arginine; Arginine Vasopressin; Biphenyl Compounds; Blood Pressure; Dose-Response Relationship, Drug; Heart Rate; Imidazoles; Kidney; Losartan; Male; NG-Nitroarginine Methyl Ester; Nitric Oxide; Phenylephrine; Purinergic Antagonists; Rats; Rats, Sprague-Dawley; Receptors, Purinergic P1; Regional Blood Flow; Renal Circulation; Serotonin; Tetrazoles; Thromboxane A2; Vascular Resistance; Vasoconstriction

1993
Angiotensin subtype 1 blockade selectively potentiates adenosine subtype 2-mediated vasodilation.
    Hypertension (Dallas, Tex. : 1979), 1993, Volume: 22, Issue:2

    Topics: Adenosine; Angiotensin II; Animals; Biphenyl Compounds; Blood Pressure; Heart Rate; Imidazoles; Injections, Intravenous; Losartan; Male; Nifedipine; Nitroglycerin; Rats; Rats, Sprague-Dawley; Tetrazoles; Vascular Resistance; Vasodilation

1993
Effect of selective angiotensin II receptor antagonism and angiotensin converting enzyme inhibition on the coronary vasculature in vivo. Intravascular two-dimensional and Doppler ultrasound studies.
    Circulation, 1993, Volume: 87, Issue:3

    Topics: Adenosine; Angiotensin Receptor Antagonists; Angiotensin-Converting Enzyme Inhibitors; Animals; Arginine; Biphenyl Compounds; Blood Flow Velocity; Coronary Circulation; Coronary Vessels; Dogs; Enalaprilat; Female; Imidazoles; Losartan; Male; NG-Nitroarginine Methyl Ester; Rest; Tetrazoles; Ultrasonography; Vasodilation

1993
AT(1) and AT(2) receptor expression and blockade after acute ischemia-reperfusion in isolated working rat hearts.
    American journal of physiology. Heart and circulatory physiology, 2002, Volume: 282, Issue:4

    Topics: Adenosine; Adrenergic alpha-Agonists; Anaerobiosis; Angiotensin-Converting Enzyme Inhibitors; Animals; Anti-Arrhythmia Agents; Cyclic GMP; Enalaprilat; Gene Expression Regulation; Heart; Hemodynamics; In Vitro Techniques; Losartan; Mitogen-Activated Protein Kinases; Myocardial Reperfusion; Myocardial Reperfusion Injury; p38 Mitogen-Activated Protein Kinases; Rats; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Time Factors; Ventricular Function, Left

2002
Divergent roles of angiotensin II AT1 and AT2 receptors in modulating coronary microvascular function.
    Circulation research, 2003, Feb-21, Volume: 92, Issue:3

    Topics: Adenosine; Angiotensin II; Angiotensin Receptor Antagonists; Animals; Arterioles; Coronary Vessels; Dose-Response Relationship, Drug; Endothelium, Vascular; Enzyme Inhibitors; Free Radical Scavengers; Imidazoles; In Vitro Techniques; Losartan; Microcirculation; NADPH Oxidases; Nitric Oxide; Pyridines; Receptor, Angiotensin, Type 1; Receptor, Angiotensin, Type 2; Receptors, Angiotensin; Superoxides; Swine; Vasoconstriction; Vasoconstrictor Agents; Vasodilation; Vasodilator Agents; Vasomotor System

2003
Vasopressin is a major vasoconstrictor involved in hindlimb vascular responses to stimulation of adenosine A(1) receptors in the nucleus of the solitary tract.
    American journal of physiology. Heart and circulatory physiology, 2009, Volume: 297, Issue:5

    Topics: Adenosine; Adenosine A1 Receptor Agonists; Adrenalectomy; Angiotensin II; Angiotensin II Type 1 Receptor Blockers; Animals; Antidiuretic Hormone Receptor Antagonists; Arginine Vasopressin; Baroreflex; Blood Pressure; Heart Rate; Hindlimb; Iliac Artery; Losartan; Male; Microinjections; Muscle, Skeletal; Norepinephrine; Rats; Rats, Sprague-Dawley; Receptor, Adenosine A1; Receptor, Angiotensin, Type 1; Receptors, Vasopressin; Regional Blood Flow; Solitary Nucleus; Sympathectomy; Time Factors; Vasoconstriction; Vasopressins

2009