Page last updated: 2024-08-23

lorcainide and piperidines

lorcainide has been researched along with piperidines in 137 studies

Research

Studies (137)

Timeframe	Studies, this research(%)	All Research%
pre-1990	121 (88.32)	18.7374
1990's	12 (8.76)	18.2507
2000's	1 (0.73)	29.6817
2010's	2 (1.46)	24.3611
2020's	1 (0.73)	2.80

Authors

Authors	Studies
Carmeliet, E; Zaman, MY	1
Jähnchen, E; Just, H; Kasper, W; Kersting, F; Meinertz, T	1
Cocco, G; Strozzi, C	1
Heimburg, P; Klotz, U; Müller-Seydlitz, P	1
Bechtold, H; Heykants, J; Jähnchen, E; Just, H; Kasper, W; Kersting, F; Meinertz, T	1
Bechtold, H; Jähnchen, E; Just, H; Kasper, W; Kersting, F; Meinertz, T	3
Fischer, C; Klotz, U; Müller, WA; Müller-Seydlitz, P; Schulz, J	1
Gmeiner, R; Gstöttner, M; Ng, CK	1
Heimburg, P; Klotz, U; Müller-Seydlitz, PM	1
Heykants, J; Michiels, M; Woestenborghs, R	1
Kesteloot, H; Stroobandt, R	2
Carmeliet, E; Janssen, PA; Marsboom, R; Van Nueten, JM; Xhonneux, R	1
De Clerck, F; Van Gorp, L; Xhonneux, R	1
Modi, NB; Veng-Pedersen, P	1
Almotrefi, AA; Dzimiri, N	3
Bryniarski, L; Dubiel, JP; Mazurek, S; Sniezek-Maciejewska, M	1
Jiang, H	1
Kuang, Y; Liu, TP	1
Bartáková, H; Hrobonová, V; Samánek, M	2
Aisaka, K; Hattori, Y; Hidaka, T; Ishihara, T; Satoh, F	1
Kates, RE; Liem, LB	1
Lampert, S; Lown, B; Podrid, PJ; Ravid, S	1
Kates, RE; Keefe, DL; Mead, RH; Winkle, RA	1
Klein, G; Schmidt, G; Wirtzfeld, A	1
Somberg, J	1
Roden, DM; Siddoway, LA; Woosley, RL	1
Engel, T; Kelliher, GJ; Kowey, P; Wetstein, L	1
Roden, DM	1
Bernard, R; de Hemptinne, J; Gillet, JM; Lewinson, H; Liebens, I; Renard, M; Shita, A; Waterschoot, P	1
Gelijkens, CF; Heykants, J; Knaeps, A; Lenoir, H; Van Peer, A; Woestenborghs, R	1
Hohnloser, SH; Lown, B; Podrid, PJ	1
Mauro, VF; Somani, P; Temesy-Armos, PN	1
Carmeliet, E	1
Fraker, TD; Somani, P; Temesy-Armos, PN	1
Chow, MS; Fieldman, A; Hanyok, JJ; Kluger, J	1
Li, ZW; Ma, X	1
Butler, B; Flowers, D; Somberg, J; Tepper, D; Torres, V	1
Anastasiou-Nana, M; Anderson, JL; Lutz, JR; Writer, SL	1
Butler, B; Jentzer, J; Keren, G; Miura, DS; Siegel, L; Somberg, JC; Tepper, D; Torres, V	1
Podrid, PJ	1
Blevins, RD; Faitel, K; Garfinkel, C; Jarandilla, R; Kerin, NZ; Mathias, P; Pesola, D; Rubenfire, M	1
Mallis, GI; Vlay, SC	1
Keefe, D; Laux, B; Miura, DS; Somberg, JC; Wynn, J	1
Czakó, E; Solti, F; Szatmáry, L	1
Echt, DS; Mason, JW; Shapiro, M; Trusso, J; Winkle, RA	1
Butler, B; Flowers, D; Keefe, D; Miura, D; Somberg, J; Torres, V	1
Grönniger, J; Jähnchen, E; Plänitz, V	1
Anastasiou-Nana, MI; Anderson, JL; Hampton, EM; Lutz, JR; Nanas, JN	1
Sanna, GP	1
Schmitz, W	1
Hillis, WS; Whiting, B	1
Somberg, JC	1
Doherty, JU; Josephson, ME; Kienzle, MG; Williams, PD; Zygmont, D	1
Duff, HJ; Oates, JA; Roden, DM; Woosley, RL	1
Lüderitz, B	1
Kates, RE; Keefe, DL; Rodriguez, I; Winkle, RA	1
Buss, J; Geiger, S; Gores, D; Heene, DL; Stegaru, B	1
Bolomo, NJ; Garcilazo, E; Milei, J; Molina, HA	1
Amery, W; Keulen, UW; Terryn, R	1
Brogden, RN; Eiriksson, Ce	1
Gordin, A; Heikkilä, J; Leinonen, H; Sundberg, S	1
Cockrell, JL; DiBianco, R; Fletcher, RD; Kostroff, LI; Singh, SN	1
Falk, RH; O'Brien, JL	1
Block, PJ; Winkle, RA	1
Pottage, A	1
Harrison, DC; Kates, RE; Woosley, RL	1
Laser, J	1
Harrison, DC; Mead, RH	1
McDevitt, DG	1
Hugenholtz, PG; Serruys, PW; Vanhaleweyk, G	1
Camm, AJ	1
Orning, OM	1
Hellestrand, KJ	1
Bettini, R; Dal Forno, P; Disertori, M; Furlanello, F; Gramegna, L; Inama, G; Vergara, G	1
Kates, RE	1
Somberg, JC; Torres, V	1
Keefe, DL	1
Lown, B; Podrid, PJ	1
Butler, B; Flowers, D; Keefe, D; Miura, DS; Somberg, JC; Tepper, D; Torres, V	1
Butler, B; Flowers, D; Keefe, D; Miura, D; Somberg, JC; Torres, V	1
Butler, B; Flowers, D; Keren, G; Maguire, W; Miura, D; Somberg, JC; Tepper, D; Willens, H	1
Harvengt, C	1
Fraker, TD; Goodenday, LS; Leighton, RF; Somani, P; Temesy-Armos, PN	1
Jähnchen, E; Plänitz, V	1
Arfiero, S; De Dominicis, E; Marcolini, F; Menghetti, L; Ometto, R; Vincenzi, M	1
Keren, G; Miura, DS; Somberg, JC	1
Gupta, RK; King, P; Shapiro, RS; Simon, V; Somani, P; Stockard, H	1
Chesnie, B; Lampert, S; Lown, B; Podrid, P	1
Cohn, PF; Mallis, GI; Singh, S; Vlay, SC	1
Ronfeld, RA	1
Jewitt, DE	1
Almotrefi, AA; Baker, JB	1
Atallah, G; Kirkorian, G; Touboul, P	1
Harrison, DC; Kates, RE; Keefe, DL	1
Atallah, G; Kirkorian, G; Moleur, P; Touboul, P	1
Kates, RE; Keefe, DL; Winkle, RA	1
Bonzel, T; Hust, MH; Just, H; Löllgen, H; Nitsche, K; Wollschläger, H	1
Fukuda, H; Goto, M; Kondo, M; Sekino, Y; Uchigasaki, T	1
Jähnchen, E; Kasper, W; Meinertz, T; Pop, T; Treese, N	1
Echt, DS; Kates, RE; Mitchell, LB; Winkle, RA	1
Amery, WK; Bruyneel, K; Heykants, J; Terryn, R	1
Bernstein, A; Cappello, G; Rothbart, ST; Saksena, S; Somani, P	1
Campbell, TJ; Vaughan Williams, EM	1
Amery, WK; Gough, DA; Heykants, JJ; Janssen, PA; Oettel, P; Towse, G; Xhonneux, R	1
Bechtold, H; Jähnchen, E; Just, J; Kasper, W; Löllgen, H; Meinertz, T; Stengel, E; Waldecker, B	1
Keefe, DL; Peters, F; Winkle, RA	1
Lüderitz, B; Manz, M; Steinbeck, G	1
Simon, V; Somani, P	1
Brachmann, J; Gao, TL; Kübler, W; Lengfelder, W; Rizos, I; Senges, J	1
Miura, DS; Somberg, JS; Sonnenblick, EN	1
Golbs, E; Klotz, U	1
Somani, P	1
Bernard, R; Debacker, M; Mostinckx, R; Shita, A	1
Kates, RE; Yee, YG	1
Abendroth, RR; Breithardt, G; Seipel, L	1
Asano, T; Atoda, H; Kasuya, Y; Shigenobu, K	1
Commerford, PJ; Lloyd, EA; Mabin, TA; Workman, LJ	1
Battistini, G; Iosa, G; Mambelli, M; Pigini, G; Pretolani, E; Zoli, I	1
Goldman, AP; Myburgh, DP; Schamroth, JM	1
di Giorgi, S; Somani, P	1
De Mey, D; Depaepe, A; Sartieaux, A	1
Bär, FW; Farré, J; Gorgels, AP; Ross, D; Vanagt, EJ; Wellens, HJ	1
Büttner-Belz, U; Evers, J	1
Cowley, AJ; Hampton, JR; Skene, A; Stainer, K	1
Chow, MS; Fisher, JR; Kluger, J; Tisdale, JE	1
Almotrefi, AA	1
Luo, X; Zeng, FD	1
Dai, DZ; Kong, RZ; Li, HT; Wang, YQ	1
Burstein, ES; Del Tredici, AL; Ma, JN; Piu, F	1
Hampton, J	1
An, JR; Li, H; Liang, J; Park, WS; Seo, MS; Xu, ZX; Yang, Y; Zha, Y; Zhuang, W	1

Reviews

21 review(s) available for lorcainide and piperidines

Article	Year
Update: cardiac antiarrhythmic drugs. Comprehensive therapy, 1989, Volume: 15, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Mexiletine; Piperidines; Propafenone; Propanolamines	1989
Antiarrhythmic drug therapy. Recent advances and current status. Cardiology, 1985, Volume: 72, Issue:5-6 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Disopyramide; Drug Administration Schedule; Encainide; Flecainide; Heart Conduction System; Humans; Imidazoles; Lidocaine; Mexiletine; Moricizine; Myocardial Contraction; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tocainide; Verapamil	1985
Clinical pharmacology of old and new antiarrhythmic drugs. Cardiovascular clinics, 1985, Volume: 15, Issue:3 Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Bretylium Compounds; Disopyramide; Encainide; Flecainide; Humans; Imipramine; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Phenytoin; Piperidines; Procainamide; Propafenone; Propiophenones; Quinidine; Tocainide	1985
Clinical pharmacology of antiarrhythmic agents. Cardiovascular clinics, 1985, Volume: 16, Issue:1 Topics: Adrenergic beta-Antagonists; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Calcium Channel Blockers; Electrophysiology; Encainide; Flecainide; Heart Conduction System; Humans; Lidocaine; Moricizine; Phenothiazines; Piperidines; Quaternary Ammonium Compounds; Sotalol; Tocainide	1985
Pharmacologic information required for design of programmed electrical stimulation protocols. Circulation, 1986, Volume: 73, Issue:2 Pt 2 Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Dogs; Drug Evaluation; Electric Stimulation; Encainide; Flecainide; Heart Conduction System; Humans; Piperidines	1986
Antiarrhythmic drug therapy (Part 2). Benefits and hazards. Chest, 1985, Volume: 88, Issue:4 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Propafenone; Propiophenones; Tocainide	1985
[Electrophysiological classification of newer antiarrhythmic drugs (author's transl)]. Klinische Wochenschrift, 1980, Sep-15, Volume: 58, Issue:18 Topics: Action Potentials; Adrenergic beta-Antagonists; Anilides; Animals; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Calcium; Disopyramide; Electrophysiology; Humans; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Quinidine; Sodium; Tocainide	1980
Antiarrhythmic drug therapy for sustained ventricular tachycardia. Heart & lung : the journal of critical care, 1984, Volume: 13, Issue:6 Topics: Adrenergic beta-Antagonists; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bethanidine; Calcium Channel Blockers; Disopyramide; Drug Therapy, Combination; Electrocardiography; Electrophysiology; Encainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Phenytoin; Piperidines; Procainamide; Quinidine; Tachycardia; Tocainide	1984
Lorcainide. A preliminary review of its pharmacodynamic properties and therapeutic efficacy. Drugs, 1984, Volume: 27, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Biological Availability; Clinical Trials as Topic; Drug Interactions; Electrophysiology; Half-Life; Hemodynamics; Humans; Kinetics; Piperidines; Wolff-Parkinson-White Syndrome	1984
Hemodynamic effects of antiarrhythmic drugs. The American journal of cardiology, 1983, Sep-22, Volume: 52, Issue:6 Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Bretylium Compounds; Calcium Channel Blockers; Disopyramide; Dose-Response Relationship, Drug; Encainide; Flecainide; Hemodynamics; Humans; Lidocaine; Mexiletine; Myocardial Contraction; Phenytoin; Piperidines; Procainamide; Quinidine; Tocainide	1983
Clinical profiles of newer class I antiarrhythmic agents--tocainide, mexiletine, encainide, flecainide and lorcainide. The American journal of cardiology, 1983, Sep-22, Volume: 52, Issue:6 Topics: Administration, Oral; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Dose-Response Relationship, Drug; Electrophysiology; Encainide; Flecainide; Hemodynamics; Humans; Injections, Intravenous; Kinetics; Lidocaine; Mexiletine; Piperidines; Tocainide	1983
Therapy with investigational antiarrhythmic drugs. The Medical clinics of North America, 1984, Volume: 68, Issue:5 Topics: Amiodarone; Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Piperidines; Tocainide	1984
Haemodynamic effects of encainide, flecainide, lorcainide and tocainide. European heart journal, 1984, Volume: 5 Suppl B Topics: Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Encainide; Flecainide; Hemodynamics; Humans; Lidocaine; Piperidines; Tocainide	1984
Cardiac electrophysiology of four new antiarrhythmic drugs--encainide, flecainide, lorcainide and tocainide. European heart journal, 1984, Volume: 5 Suppl B Topics: Action Potentials; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Electrocardiography; Electrophysiology; Encainide; Flecainide; Heart; Heart Conduction System; Humans; Lidocaine; Piperidines; Sinoatrial Node; Tocainide	1984
Comparison of the efficacy of newly developed antiarrhythmic drugs in the treatment of ventricular tachyarrhythmias. European heart journal, 1984, Volume: 5 Suppl B Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Coronary Disease; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Myocardial Infarction; Piperidines; Tachycardia; Tocainide; Ventricular Fibrillation	1984
Metabolites of cardiac antiarrhythmic drugs: their clinical role. Annals of the New York Academy of Sciences, 1984, Volume: 432 Topics: Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Disopyramide; Encainide; Humans; Lidocaine; Piperidines; Procainamide; Quinidine	1984
Comparative pharmacokinetics of new antiarrhythmic drugs. American heart journal, 1980, Volume: 100, Issue:6 Pt 2 Topics: Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Disopyramide; Humans; Kinetics; Mexiletine; Piperidines; Tocainide; Verapamil	1980
Hemodynamic effects of newer antiarrhythmic drugs. American heart journal, 1980, Volume: 100, Issue:6 Pt 2 Topics: Acebutolol; Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Atenolol; Benzeneacetamides; Disopyramide; Dogs; Hemodynamics; Humans; Mexiletine; Piperidines; Tocainide; Verapamil	1980
New antiarrhythmic drugs: their place in therapy. Drugs, 1981, Volume: 22, Issue:5 Topics: Action Potentials; Ajmaline; Amiodarone; Anilides; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bretylium Tosylate; Disopyramide; Encainide; Hemodynamics; Humans; Kinetics; Moricizine; Morpholines; Phenothiazines; Piperidines; Verapamil	1981
[New antiarrythmic drugs: mexiletine, tocainide, lorcainide, encainide, flecainide, propafenone, cipralan, sotalol]. Annales de cardiologie et d'angeiologie, 1982, Volume: 31, Issue:7 Topics: Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Electrophysiology; Encainide; Flecainide; Hemodynamics; Humans; Imidazoles; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Sotalol; Tocainide	1982
Lorcainide (R 15 889), a first review. Acta cardiologica, 1981, Volume: 36, Issue:3 Topics: Absorption; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Dogs; Electrocardiography; Guinea Pigs; Half-Life; Heart Conduction System; Hemodynamics; Humans; Kinetics; Lethal Dose 50; Mice; Myocardial Contraction; Piperidines; Rats	1981

Trials

22 trial(s) available for lorcainide and piperidines

Article	Year
Initial clinical experience of lorcainide (Ro 13-1042), a new antiarrhythmic agent. European journal of clinical pharmacology, 1978, Nov-16, Volume: 14, Issue:2 Topics: Acetanilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Clinical Trials as Topic; Exercise Test; Female; Humans; Male; Middle Aged; Piperidines	1978
Disposition and antiarrhythmic effect of lorcainide. International journal of clinical pharmacology and biopharmacy, 1979, Volume: 17, Issue:4 Topics: Acetanilides; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Clinical Trials as Topic; Dealkylation; Electrocardiography; Female; Half-Life; Heart Ventricles; Humans; Kinetics; Male; Middle Aged; Piperidines	1979
Acute effects of antiarrhythmic drugs on stable ventricular premature beats. Controlled comparison of lorcainide and lidocaine. European journal of clinical pharmacology, 1985, Volume: 27, Issue:6 Topics: Adult; Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Cardiac Complexes, Premature; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; Humans; Lidocaine; Male; Middle Aged; Piperidines; Random Allocation; Time Factors	1985
Intravenous lorcainide for symptomatic ventricular tachyarrhythmias: comparison with lidocaine and oral lorcainide. American heart journal, 1988, Volume: 115, Issue:4 Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Benzeneacetamides; Female; Humans; Infusions, Intravenous; Lidocaine; Male; Middle Aged; Piperidines; Random Allocation	1988
Comparison of intravenous lorcainide with lidocaine for acute therapy of complex ventricular arrhythmias: results of a randomized study with crossover option. Journal of the American College of Cardiology, 1985, Volume: 5, Issue:2 Pt 1 Topics: Adult; Aged; Arrhythmias, Cardiac; Benzeneacetamides; Clinical Trials as Topic; Drug Administration Schedule; Electrocardiography; Female; Humans; Infusions, Parenteral; Lidocaine; Male; Middle Aged; Piperidines; Prospective Studies; Random Allocation; Time Factors	1985
Therapy for late post infarction ventricular tachycardia. Angiology, 1985, Volume: 36, Issue:3 Topics: Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Cardiac Pacing, Artificial; Clinical Trials as Topic; Electrocardiography; Female; Heart Rate; Heart Ventricles; Humans; Male; Middle Aged; Myocardial Infarction; Piperidines; Tachycardia	1985
Intravenous lorcainide versus lidocaine in the treatment of frequent and complex ventricular arrhythmias. American heart journal, 1986, Volume: 111, Issue:3 Topics: Aged; Arrhythmias, Cardiac; Benzeneacetamides; Chronic Disease; Electrocardiography; Female; Humans; Infusions, Parenteral; Kinetics; Lidocaine; Male; Middle Aged; Monitoring, Physiologic; Myocardial Infarction; Piperidines; Random Allocation	1986
Intravenous and oral lorcainide: assessment of central nervous system toxicity and antiarrhythmic efficacy. American heart journal, 1986, Volume: 111, Issue:3 Topics: Administration, Oral; Adolescent; Adult; Aged; Arrhythmias, Cardiac; Benzeneacetamides; Central Nervous System; Female; Heart Ventricles; Humans; Infusions, Parenteral; Male; Middle Aged; Monitoring, Physiologic; Piperidines	1986
Long-term lorcainide therapy in patients with ventricular tachycardia. American heart journal, 1985, Volume: 109, Issue:1 Topics: Benzeneacetamides; Cardiac Pacing, Artificial; Drug Evaluation; Electrocardiography; Female; Heart Ventricles; Humans; Injections, Intravenous; Lidocaine; Male; Middle Aged; Piperidines; Procainamide; Tachycardia	1985
Selection of an antiarrhythmic drug for a sudden-death-prevention trial. American heart journal, 1982, Volume: 103, Issue:4 Pt 2 Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bretylium Compounds; Clinical Trials as Topic; Death, Sudden; Encainide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Moricizine; Morpholines; Phenothiazines; Piperidines; Tocainide; Verapamil	1982
[Lorcainide in stable ventricular extrasystole. A double-blind study with 48-hour continuous ECG recording]. Deutsche medizinische Wochenschrift (1946), 1984, Nov-30, Volume: 109, Issue:48 Topics: Adult; Anti-Arrhythmia Agents; Benzeneacetamides; Cardiac Complexes, Premature; Clinical Trials as Topic; Double-Blind Method; Electrocardiography; Female; Humans; Male; Middle Aged; Piperidines; Placebos; Time Factors	1984
Control of ventricular ectopic beats with intravenous lorcainide maintained by oral doses. International journal of cardiology, 1983, Volume: 3, Issue:3 Topics: Administration, Oral; Arrhythmias, Cardiac; Benzeneacetamides; Clinical Trials as Topic; Double-Blind Method; Heart Ventricles; Humans; Injections, Intravenous; Piperidines	1983
Lorcainide. A preliminary review of its pharmacodynamic properties and therapeutic efficacy. Drugs, 1984, Volume: 27, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Biological Availability; Clinical Trials as Topic; Drug Interactions; Electrophysiology; Half-Life; Hemodynamics; Humans; Kinetics; Piperidines; Wolff-Parkinson-White Syndrome	1984
Lorcainide in the prophylaxis of ventricular arrhythmias in acute myocardial infarction. Annals of clinical research, 1984, Volume: 16, Issue:1 Topics: Administration, Oral; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Clinical Trials as Topic; Female; Humans; Infusions, Parenteral; Lidocaine; Male; Middle Aged; Myocardial Infarction; Pindolol; Piperidines; Random Allocation	1984
Lorcainide for high-frequency ventricular arrhythmia: preliminary results of a short-term double-blind and placebo-controlled crossover study and long-term follow-up. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Exercise Test; Female; Follow-Up Studies; Heart Ventricles; Hemodynamics; Humans; Male; Middle Aged; Piperidines; Random Allocation	1984
Lorcainide. A comparative trial with quinidine gluconate in patients with previously untreated ventricular arrhythmias. Chest, 1984, Volume: 86, Issue:4 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Clinical Trials as Topic; Female; Heart Ventricles; Humans; Male; Middle Aged; Piperidines; Quinidine; Random Allocation	1984
Comparison of lorcainide and quinidine in the treatment of ventricular ectopy. Chest, 1984, Volume: 86, Issue:1 Topics: Adult; Aged; Arrhythmias, Cardiac; Benzeneacetamides; Female; Humans; Male; Middle Aged; Piperidines; Quinidine; Tachycardia	1984
Bioavailability and saturation of the presystemic metabolism of oral lorcainide therapy initiated in three different dose regimens. European journal of clinical pharmacology, 1983, Volume: 24, Issue:4 Topics: Aged; Benzeneacetamides; Biological Availability; Biotransformation; Drug Administration Schedule; Female; Humans; Male; Middle Aged; Piperidines	1983
Comparison of the antiarrhythmic activity of mexiletine and lorcainide on ventricular arrhythmias. Zeitschrift fur Kardiologie, 1982, Volume: 71, Issue:1 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Clinical Trials as Topic; Coronary Disease; Dose-Response Relationship, Drug; Electrocardiography; Female; Heart Failure; Heart Ventricles; Humans; Male; Mexiletine; Middle Aged; Mitral Valve Prolapse; Piperidines; Propylamines; Random Allocation	1982
Randomized double-blind placebo controlled crossover trial documenting oral lorcainide efficacy in suppression of symptomatic ventricular tachyarrhythmias. American heart journal, 1982, Volume: 103, Issue:4 Pt 1 Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Anti-Arrhythmia Agents; Benzeneacetamides; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Electrocardiography; Female; Humans; Male; Middle Aged; Piperidines; Placebos; Random Allocation; Tachycardia	1982
Evaluation of lorcainide, a new anti-arrhythmic agent. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1981, Dec-12, Volume: 60, Issue:24 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Drug Evaluation; Humans; Lidocaine; Piperidines; Time Factors	1981
The effect of lorcainide on arrhythmias and survival in patients with acute myocardial infarction: an example of publication bias. International journal of cardiology, 1993, Jul-01, Volume: 40, Issue:2 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Double-Blind Method; Electrocardiography; Female; Humans; Male; Middle Aged; Myocardial Infarction; Piperidines; Publishing; Survival Analysis; Time Factors	1993

Other Studies

95 other study(ies) available for lorcainide and piperidines

Article	Year
Comparative effects of lignocaine and lorcainide on conduction in the Langendorff-perfused guinea-pig heart. Cardiovascular research, 1979, Volume: 13, Issue:8 Topics: Acetamides; Animals; Anti-Arrhythmia Agents; Atrioventricular Node; Benzeneacetamides; Cardiac Complexes, Premature; Cardiac Pacing, Artificial; Guinea Pigs; Heart Conduction System; In Vitro Techniques; Lidocaine; Perfusion; Piperidines; Time Factors	1979
[Cardiovascular effects of lorcainid, a new anti-arrhythmic substance]. Verhandlungen der Deutschen Gesellschaft fur Innere Medizin, 1978, Issue:84 Topics: Acetanilides; Anesthetics, Local; Anti-Arrhythmia Agents; Benzeneacetamides; Blood Pressure; Cardiomegaly; Coronary Disease; Depression, Chemical; Mitral Valve Insufficiency; Piperidines; Stroke Volume	1978
Lorcainide. I. Saturable presystemic elimination. Clinical pharmacology and therapeutics, 1979, Volume: 26, Issue:2 Topics: Acetanilides; Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Aorta; Aorta, Abdominal; Arrhythmias, Cardiac; Benzeneacetamides; Blood; Blood Proteins; Female; Hepatic Veins; Humans; In Vitro Techniques; Injections, Intravenous; Male; Middle Aged; Piperidines; Protein Binding; Pulmonary Artery	1979
Lorcainide. II. Plasma concentration-effect relationship. Clinical pharmacology and therapeutics, 1979, Volume: 26, Issue:2 Topics: Acetanilides; Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Electrocardiography; Female; Humans; In Vitro Techniques; Infusions, Parenteral; Injections, Intravenous; Male; Middle Aged; Piperidines	1979
Alterations in the disposition of differently cleared drugs in patients with cirrhosis. Clinical pharmacology and therapeutics, 1979, Volume: 26, Issue:2 Topics: Acetanilides; Adult; Aged; Anti-Arrhythmia Agents; Antipyrine; Benzeneacetamides; Humans; Liver; Liver Circulation; Liver Cirrhosis, Alcoholic; Middle Aged; Piperidines	1979
Intracardiac electrophysiological effects of lorcainide in man. European journal of clinical pharmacology, 1979, May-21, Volume: 15, Issue:4 Topics: Acetanilides; Adult; Aged; Anti-Arrhythmia Agents; Atrioventricular Node; Benzeneacetamides; Bundle of His; Electric Stimulation; Electrocardiography; Electrophysiology; Female; Heart; Heart Conduction System; Humans; Male; Middle Aged; Piperidines; Purkinje Cells; Refractory Period, Electrophysiological	1979
Lorcainide infusion in the treatment of ventricular premature beats (VPB). European journal of clinical pharmacology, 1979, Volume: 16, Issue:1 Topics: Acetanilides; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Electrocardiography; Female; Heart Ventricles; Humans; Infusions, Parenteral; Male; Middle Aged; Piperidines; Time Factors	1979
Simultaneous gas chromatographic determination of lorcainide hydrochloride and three of its principal metabolites in biological samples. Journal of chromatography, 1979, Oct-11, Volume: 164, Issue:2 Topics: Acetanilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Dogs; Feces; Gas Chromatography-Mass Spectrometry; Humans; Myocardium; Piperidines; Time Factors	1979
Clinical experience with lorcainide (R 15 889), a new anti-arrhythmic drug. Archives internationales de pharmacodynamie et de therapie, 1977, Volume: 230, Issue:2 Topics: Acetamides; Administration, Oral; Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Electrocardiography; Humans; Injections, Intravenous; Male; Middle Aged; Piperidines	1977
Antiarrhythmic, electrophysiologic and hemodynamic effects of lorcainide. Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 231, Issue:1 Topics: Acetamides; Acetylcholine; Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Cats; Cattle; Coronary Vessels; Dogs; Electrocardiography; Female; Guinea Pigs; Heart; Hemodynamics; In Vitro Techniques; Ligation; Male; Membrane Potentials; Myocardial Contraction; Ouabain; Piperidines; Refractory Period, Electrophysiological	1978
Effect of lorcainide, a new antiarrhythmic compound, on the changes in heart rhythm induced by intravenous injection of adenosine-5'-diphosphate in rats. Archives internationales de pharmacodynamie et de therapie, 1978, Volume: 231, Issue:2 Topics: Acetamides; Adenosine Diphosphate; Animals; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Drug Interactions; Heart Rate; Lidocaine; Male; Piperidines; Procaine; Propanolamines; Rats; Thrombocytopenia; Time Factors	1978
Pharmacodynamic system analysis of the biophase level predictor and the transduction function. Journal of pharmaceutical sciences, 1992, Volume: 81, Issue:9 Topics: Alfentanil; Animals; Benzeneacetamides; Humans; Mathematics; Models, Theoretical; Pharmacokinetics; Pharmacology; Piperidines; Rabbits; Theophylline	1992
Comparative effects of procainamide, tocainide and lorcainide on Na(+)-K(+)-ATPase in guinea pig heart preparations. General pharmacology, 1991, Volume: 22, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Female; Guinea Pigs; Heart; In Vitro Techniques; Lidocaine; Male; Myocardium; Ouabain; Piperidines; Procainamide; Sodium-Potassium-Exchanging ATPase; Tocainide	1991
Variations in potassium concentration modify the inhibitory effect of lorcainide on myocardial Na(+)-K(+)-ATPase activity. British journal of pharmacology, 1991, Volume: 104, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Microsomes; Myocardium; Piperidines; Potassium; Sodium-Potassium-Exchanging ATPase	1991
Influence of lorcainide on microsomal Na+, K(+)-ATPase in guinea-pig isolated heart preparations. British journal of pharmacology, 1991, Volume: 102, Issue:2 Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Female; Guinea Pigs; Heart; In Vitro Techniques; Male; Myocardium; Ouabain; Piperidines; Sodium-Potassium-Exchanging ATPase	1991
[The effects of lorcainide on the ECG pattern and left ventricular function in a patient with recurrent ventricular tachycardia]. Kardiologia polska, 1990, Volume: 33, Issue:9-10 Topics: Anti-Arrhythmia Agents; Benzeneacetamides; Electrocardiography; Humans; Male; Middle Aged; Piperidines; Recurrence; Tachycardia; Ventricular Function, Left	1990
[Clinical electrophysiologic effects of lorcainide in patients and its effect on the conduction of accessory pathway in Wolff-Parkinson-White syndrome]. Zhonghua xin xue guan bing za zhi, 1990, Volume: 18, Issue:3 Topics: Adolescent; Adult; Anti-Arrhythmia Agents; Benzeneacetamides; Child; Electrophysiology; Female; Heart Conduction System; Humans; Male; Middle Aged; Piperidines; Tachycardia, Supraventricular; Wolff-Parkinson-White Syndrome	1990
Rate-dependent depression of maximal rate of depolarization in guinea pig papillary muscle action potentials by changrolin. Zhongguo yao li xue bao = Acta pharmacologica Sinica, 1990, Volume: 11, Issue:3 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Female; Guinea Pigs; In Vitro Techniques; Male; Mexiletine; Papillary Muscles; Piperidines; Quinazolines; Quinidine	1990
Lorcainide treatment of Wolff-Parkinson-White syndrome in children and adolescents. Pediatric cardiology, 1987, Volume: 8, Issue:1 Topics: Adolescent; Anti-Arrhythmia Agents; Benzeneacetamides; Cardiac Complexes, Premature; Child; Child, Preschool; Electrocardiography; Female; Heart Conduction System; Humans; Infant; Infant, Newborn; Male; Piperidines; Tachycardia, Supraventricular; Wolff-Parkinson-White Syndrome	1987
Effect of SUN 1165, a new potent antiarrhythmic agent, on the kinetics of rate-dependent block of Na channels and ventricular conduction of extrasystoles. Journal of cardiovascular pharmacology, 1988, Volume: 11, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Cardiac Complexes, Premature; Disopyramide; Guinea Pigs; Heart Conduction System; Heart Ventricles; In Vitro Techniques; Ion Channels; Lidocaine; Male; Mexiletine; Papillary Muscles; Piperidines; Sodium	1988
Congestive heart failure induced by six of the newer antiarrhythmic drugs. Journal of the American College of Cardiology, 1989, Nov-01, Volume: 14, Issue:5 Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anilides; Anti-Arrhythmia Agents; Benzeneacetamides; Encainide; Female; Heart Failure; Humans; Lidocaine; Male; Mexiletine; Middle Aged; Moricizine; Phenothiazines; Piperidines; Propafenone; Risk Factors; Stroke Volume; Tocainide	1989
Chronic lorcainide therapy for symptomatic premature ventricular complexes: efficacy, pharmacokinetics and evidence for norlorcainide antiarrhythmic effect. The American journal of cardiology, 1985, Jan-01, Volume: 55, Issue:1 Topics: Benzeneacetamides; Cardiac Complexes, Premature; Electrocardiography; Female; Half-Life; Heart Ventricles; Humans; Kinetics; Male; Middle Aged; Piperidines; Time Factors	1985
[Hemodynamic repercussions and clinical tolerance of 6 class I anti-arrhythmia agents in acute myocardial infarction]. Annales de cardiologie et d'angeiologie, 1986, Volume: 35, Issue:4 Topics: Ajmaline; Anti-Arrhythmia Agents; Benzeneacetamides; Fluorenes; Hemodynamics; Lidocaine; Mexiletine; Myocardial Infarction; Piperidines; Tocainide	1986
The use and limitations of deuterated lorcainide in metabolism and pharmacokinetic studies. Biomedical mass spectrometry, 1985, Volume: 12, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Deuterium; Dogs; Gas Chromatography-Mass Spectrometry; Piperidines	1985
Drug interaction between lorcainide and rifampicin. European journal of clinical pharmacology, 1987, Volume: 31, Issue:6 Topics: Arrhythmias, Cardiac; Benzeneacetamides; Drug Interactions; Humans; Male; Middle Aged; Piperidines; Rifampin	1987
Comparison in vitro of the electrophysiological effects of lorcainide and its metabolite norlorcainide. European journal of pharmacology, 1987, Jan-06, Volume: 133, Issue:1 Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Blood Proteins; Electric Stimulation; Guinea Pigs; Heart; In Vitro Techniques; Kinetics; Membrane Potentials; Piperidines; Protein Binding	1987
Pharmacokinetic implications of lorcainide therapy in patients with normal and depressed cardiac function. Journal of clinical pharmacology, 1987, Volume: 27, Issue:2 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Female; Heart Diseases; Hemodynamics; Humans; Male; Middle Aged; Piperidines	1987
Lorcainide for the treatment of refractory ventricular tachycardia: clinical and electrophysiologic results. Journal of clinical pharmacology, 1987, Volume: 27, Issue:4 Topics: Adult; Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Drug Resistance; Electrocardiography; Female; Humans; Male; Middle Aged; Piperidines; Tachycardia	1987
[Effect of lorcainide on experimental arrhythmias in comparison with other antiarrhythmic agents]. Yao xue xue bao = Acta pharmaceutica Sinica, 1986, Volume: 21, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Cats; Female; Guinea Pigs; In Vitro Techniques; Male; Piperidines; Rats	1986
Long term lorcainide therapy guided by electrophysiology studies. Acta cardiologica, 1985, Volume: 40, Issue:6 Topics: Administration, Oral; Anti-Arrhythmia Agents; Benzeneacetamides; Blood Pressure; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart Rate; Humans; Infusions, Parenteral; Lidocaine; Male; Middle Aged; Piperidines; Procainamide; Tachycardia	1985
Efficacy and tolerance of intravenous lorcainide in patients with normal and impaired intraventricular conduction. Acta cardiologica, 1985, Volume: 40, Issue:6 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Blood Pressure; Electrocardiography; Female; Heart Rate; Humans; Infusions, Parenteral; Male; Middle Aged; Piperidines	1985
Lorcainide therapy in a cardiac arrest population. American heart journal, 1986, Volume: 111, Issue:4 Topics: Arrhythmias, Cardiac; Benzeneacetamides; Blood Pressure; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart Arrest; Humans; Male; Middle Aged; Piperidines; Procainamide; Recurrence	1986
Electrophysiological characteristics of lorcainide, a new antiarrhythmic drug. International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:1 Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Female; Heart Conduction System; Humans; Male; Middle Aged; Piperidines; Refractory Period, Electrophysiological; Tachycardia	1986
Treatment with oral lorcainide in patients with sustained ventricular tachycardia and fibrillation. American heart journal, 1985, Volume: 109, Issue:1 Topics: Administration, Oral; Benzeneacetamides; Cardiac Pacing, Artificial; Humans; Male; Middle Aged; Piperidines; Tachycardia; Ventricular Fibrillation	1985
Prehepatic and hepatic first-pass metabolism of lorcainide in rats. Arzneimittel-Forschung, 1985, Volume: 35, Issue:6 Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Kinetics; Liver; Male; Piperidines; Rats; Rats, Inbred Strains	1985
Initial and long-term outpatient experience with lorcainide for suppression of malignant and potentially malignant ventricular arrhythmias. American heart journal, 1985, Volume: 110, Issue:6 Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Benzeneacetamides; Dose-Response Relationship, Drug; Drug Tolerance; Electrocardiography; Female; Humans; Male; Middle Aged; Piperidines; Time Factors	1985
New drugs in the management of ventricular arrhythmias. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:10 Topics: Acecainide; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Bretylium Compounds; Drug Interactions; Encainide; Flecainide; Heart Ventricles; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Propafenone; Propiophenones; Tocainide	1984
Antiarrhythmic drugs. British medical journal (Clinical research ed.), 1983, Apr-23, Volume: 286, Issue:6374 Topics: Adrenergic beta-Antagonists; Amiodarone; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Disopyramide; Flecainide; Humans; Kinetics; Lidocaine; Mexiletine; Piperidines; Procainamide; Quinidine; Tocainide; Verapamil	1983
New directions in antiarrhythmic drug therapy. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Adrenergic beta-Antagonists; Ajmaline; Amiodarone; Anilides; Anti-Arrhythmia Agents; Aprindine; Benzeneacetamides; Bepridil; Bethanidine; Bretylium Tosylate; Death, Sudden; Disopyramide; Encainide; Flecainide; Humans; Lidocaine; Mexiletine; Moricizine; Phenothiazines; Piperidines; Procainamide; Propafenone; Propiophenones; Pyrrolidines; Quinidine; Tachycardia; Tocainide; Verapamil	1984
[Drug therapy of arrhythmia in coronary cardiopathy]. La Clinica terapeutica, 1983, Apr-15, Volume: 105, Issue:1 Topics: Amiodarone; Anti-Arrhythmia Agents; Aprindine; Arrhythmias, Cardiac; Benzeneacetamides; Cardiac Complexes, Premature; Coronary Disease; Disopyramide; Electrocardiography; Humans; Lidocaine; Mexiletine; Piperidines; Propafenone; Propiophenones; Tachycardia; Tocainide	1983
Pharmacodynamics of the initiation of antiarrhythmic therapy with lorcainide. The American journal of cardiology, 1984, Feb-01, Volume: 53, Issue:4 Topics: Administration, Oral; Adult; Aged; Ambulatory Care; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Cardiac Complexes, Premature; Dose-Response Relationship, Drug; Electrocardiography; Female; Humans; Kinetics; Male; Middle Aged; Piperidines; Sleep Wake Disorders; Time Factors	1984
Effects of lorcainide and amiodarone on stress-induced myocardial damage in the rat. Acta cardiologica, 1984, Volume: 39, Issue:5 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Benzofurans; Cardiomyopathies; Female; Male; Myocardium; Necrosis; Piperidines; Rats; Rats, Inbred Strains; Stress, Physiological	1984
Clinical importance of metabolites of antiarrhythmic drugs. The American journal of cardiology, 1984, Jan-01, Volume: 53, Issue:1 Topics: Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Chemical Phenomena; Chemistry; Dogs; Encainide; Humans; Piperidines	1984
Intractable tachycardia and a dead battery. Hospital practice (Office ed.), 1984, Volume: 19, Issue:10 Topics: Aged; Amiodarone; Anti-Arrhythmia Agents; Benzeneacetamides; Electric Countershock; Electric Injuries; Electric Power Supplies; Humans; Male; Mexiletine; Pacemaker, Artificial; Piperidines; Tachycardia; Time Factors	1984
The clinical pharmacology of lidocaine congeners--review of encainide, flecainide, lorcainide and tocainide. European heart journal, 1984, Volume: 5 Suppl B Topics: Anilides; Benzeneacetamides; Encainide; Flecainide; Humans; Kinetics; Lidocaine; Piperidines; Tocainide	1984
The use of tocainide, encainide, lorcainide and flecainide for supraventricular arrhythmias. European heart journal, 1984, Volume: 5 Suppl B Topics: Anilides; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Atrial Fibrillation; Atrioventricular Node; Benzeneacetamides; Encainide; Flecainide; Heart Atria; Humans; Lidocaine; Piperidines; Tachycardia; Tocainide; Wolff-Parkinson-White Syndrome	1984
Worsening of arrhythmias during pharmacological treatment. Giornale italiano di cardiologia, 1984, Volume: 14, Issue:10 Topics: Adolescent; Adult; Aged; Ajmaline; Amiodarone; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Child; Disopyramide; Female; Follow-Up Studies; Humans; Lidocaine; Male; Middle Aged; Nadolol; Piperidines; Propafenone; Propanolamines; Propiophenones; Tocainide	1984
New directions in antiarrhythmic drug therapy: the development of a promising new agent, lorcainide. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Anti-Arrhythmia Agents; Benzeneacetamides; Humans; Piperidines	1984
Pharmacology of lorcainide. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Cats; Dogs; Electrophysiology; Hemodynamics; Humans; Kinetics; Piperidines; Tissue Distribution	1984
Management of malignant ventricular arrhythmia--experience with lorcainide. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Dose-Response Relationship, Drug; Drug Evaluation; Electrophysiology; Follow-Up Studies; Heart Ventricles; Humans; Monitoring, Physiologic; Piperidines	1984
Lorcainide therapy for the high-risk patient post myocardial infarction. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Blood Pressure; Death, Sudden; Drug Evaluation; Electrocardiography; Female; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Myocardial Infarction; Piperidines; Procainamide; Risk; Tachycardia	1984
Evaluation of lorcainide in patients with symptomatic ventricular tachycardia. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Anti-Arrhythmia Agents; Benzeneacetamides; Drug Evaluation; Electric Stimulation; Electrocardiography; Female; Hemodynamics; Humans; Lidocaine; Male; Middle Aged; Piperidines; Procainamide; Tachycardia	1984
Comparison of noninvasive arrhythmia induction techniques with electrophysiologic studies and evaluation of lorcainide in patients with symptomatic ventricular tachycardia. The American journal of cardiology, 1984, Aug-13, Volume: 54, Issue:4 Topics: Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Dose-Response Relationship, Drug; Drug Evaluation; Electric Stimulation; Electrophysiology; Exercise Test; Female; Heart Arrest; Hemodynamics; Humans; Male; Middle Aged; Piperidines; Procainamide; Syncope; Tachycardia	1984
Drugs recently released in Belgium. Acta clinica Belgica, 1984, Volume: 39, Issue:3 Topics: Aminoglutethimide; Anti-Arrhythmia Agents; Antineoplastic Agents; Benzeneacetamides; Female; Humans; Middle Aged; Piperidines	1984
Hyponatremia in patients treated with lorcainide, a new antiarrhythmic drug. American heart journal, 1984, Volume: 108, Issue:6 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Female; Humans; Hyponatremia; Inappropriate ADH Syndrome; Male; Middle Aged; Piperidines; Potassium; Sodium; Vasopressins	1984
Effect of enzyme induction on the disposition of lorcainide in rats following intravenous and oral administration. Arzneimittel-Forschung, 1984, Volume: 34, Issue:6 Topics: Administration, Oral; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Biological Availability; Enzyme Induction; Injections, Intravenous; Kinetics; Male; Piperidines; Rats; Rats, Inbred Strains	1984
[Personal experience with the use of Lorcainide in the treatment of Wolff-Parkinson-White syndrome in infants and older children]. Ceskoslovenska pediatrie, 1983, Volume: 38, Issue:7 Topics: Adolescent; Anti-Arrhythmia Agents; Benzeneacetamides; Child; Child, Preschool; Female; Humans; Infant; Infant, Newborn; Infant, Newborn, Diseases; Male; Piperidines; Wolff-Parkinson-White Syndrome	1983
[Lorcainide in the prevention of ventricular arrhythmias in myocardial infarct]. Minerva cardioangiologica, 1983, Volume: 31, Issue:11 Topics: Adult; Aged; Arrhythmias, Cardiac; Benzeneacetamides; Drug Evaluation; Female; Heart Ventricles; Humans; Male; Middle Aged; Myocardial Infarction; Piperidines	1983
Pacing termination of ventricular tachycardia: influence of antiarrhythmic-slowed ectopic rate. American heart journal, 1984, Volume: 107, Issue:4 Topics: Adult; Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart Rate; Heart Ventricles; Humans; Lidocaine; Male; Middle Aged; Piperidines; Tachycardia	1984
Lorcainide kinetics and protein binding in patients with end-stage renal disease. International journal of clinical pharmacology, therapy, and toxicology, 1984, Volume: 22, Issue:3 Topics: Adult; Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Blood Proteins; Half-Life; Humans; Kidney Failure, Chronic; Kinetics; Male; Middle Aged; Piperidines; Protein Binding	1984
Lorcainide in patients with refractory ventricular tachyarrhythmia. Journal of the American College of Cardiology, 1984, Volume: 3, Issue:6 Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Exercise Test; Female; Humans; Male; Middle Aged; Piperidines; Tachycardia; Ventricular Fibrillation	1984
Antifibrillatory efficacy of encainide, loracainide and ORG 6001 compared with lignocaine in isolated hearts of rabbits and guinea-pigs. British journal of pharmacology, 1981, Volume: 73, Issue:2 Topics: Androstanols; Anilides; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Encainide; Female; Guinea Pigs; Heart Rate; In Vitro Techniques; Lidocaine; Male; Myocardial Contraction; Ouabain; Piperidines; Rabbits; Species Specificity	1981
[Electrophysiologic effects of lorcainide (R 15889) in man]. Archives des maladies du coeur et des vaisseaux, 1981, Volume: 74, Issue:11 Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Electrophysiology; Female; Heart; Heart Conduction System; Humans; Male; Middle Aged; Piperidines	1981
Lorcainide disposition kinetics in arrhythmia patients. Clinical pharmacology and therapeutics, 1983, Volume: 33, Issue:1 Topics: Administration, Oral; Adult; Aged; Arrhythmias, Cardiac; Benzeneacetamides; Female; Half-Life; Humans; Injections, Intravenous; Kinetics; Male; Middle Aged; Piperidines; Time Factors	1983
[Arrhythmogenic anti-arrhythmia agents]. Cardiology, 1983, Volume: 70 Suppl 1 Topics: Adult; Aged; Ajmaline; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Electrocardiography; Female; Humans; Male; Middle Aged; Piperidines; Syncope; Time Factors	1983
[Effects of lorcainide, a new antiarrhythmic agent, on experimental cardiac arrhythmias]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica, 1983, Volume: 81, Issue:2 Topics: Acetylcholine; Aconitine; Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Coronary Vessels; Disopyramide; Dogs; Female; Guinea Pigs; Ligation; Male; Ouabain; Piperidines	1983
Electrophysiologic effects of lorcainide on the accessory pathway in the Wolff-Parkinson-White syndrome. The American journal of cardiology, 1983, Volume: 51, Issue:10 Topics: Adolescent; Adult; Aged; Anti-Arrhythmia Agents; Atrial Fibrillation; Benzeneacetamides; Drug Evaluation; Electrocardiography; Female; Heart Conduction System; Humans; Male; Middle Aged; Piperidines; Tachycardia; Wolff-Parkinson-White Syndrome	1983
Comparison of the electrophysiologic effects of intravenous and oral lorcainide in patients with recurrent ventricular tachycardia. Circulation, 1983, Volume: 68, Issue:2 Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Electrocardiography; Heart Ventricles; Humans; Infusions, Parenteral; Injections, Intravenous; Middle Aged; Piperidines; Recurrence; Tachycardia	1983
Clinical and electrophysiologic effects of chronic lorcainide therapy in refractory ventricular tachycardia. Journal of the American College of Cardiology, 1983, Volume: 2, Issue:3 Topics: Adult; Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Cardiac Pacing, Artificial; Drug Evaluation; Electrocardiography; Electrophysiology; Female; Humans; Male; Middle Aged; Piperidines; Sleep Wake Disorders; Tachycardia; Time Factors	1983
Voltage- and time-dependent depression of maximum rate of depolarisation of guinea-pig ventricular action potentials by two new antiarrhythmic drugs, flecainide and lorcainide. Cardiovascular research, 1983, Volume: 17, Issue:5 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Dose-Response Relationship, Drug; Electric Conductivity; Female; Flecainide; Guinea Pigs; Heart; Heart Ventricles; In Vitro Techniques; Kinetics; Male; Piperidines; Time Factors; Ventricular Function	1983
Electrophysiological effects of lorcainide in sinoatrial disease and in Wolff-Parkinson-White syndrome. European heart journal, 1982, Volume: 3, Issue:1 Topics: Adult; Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Cardiac Pacing, Artificial; Female; Heart Block; Heart Conduction System; Heart Rate; Humans; Male; Middle Aged; Piperidines; Sinoatrial Block; Sinoatrial Node; Time Factors; Wolff-Parkinson-White Syndrome	1982
Rapid and simple method for determination of lorcainide, a new antiarrhythmic drug, and its major metabolite, norlorcainide, by high-performance liquid chromatography. Journal of chromatography, 1982, Sep-10, Volume: 231, Issue:2 Topics: Anti-Arrhythmia Agents; Benzeneacetamides; Chromatography, High Pressure Liquid; Humans; Piperidines	1982
Arrhythmogenic effects of toxic concentrations of the antiarrhythmic drug lorcainide on the isolated canine ventricle. The Journal of pharmacology and experimental therapeutics, 1982, Volume: 223, Issue:2 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Dogs; Heart; Heart Conduction System; Heart Ventricles; Piperidines; Ventricular Function	1982
[Use of programmed cardiostimulation for the choice of the antiarrhythmic therapy]. Terapevticheskii arkhiv, 1982, Volume: 54, Issue:11 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Cardiac Pacing, Artificial; Drug Evaluation; Female; Humans; Male; Middle Aged; Piperidines; Time Factors	1982
The pharmacokinetics and tissue distribution of the new antiarrhythmic agent lorcainide (R 15889) in rats. Arzneimittel-Forschung, 1980, Volume: 30, Issue:4 Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Biotransformation; Dealkylation; Half-Life; Kinetics; Male; Piperidines; Rats; Time Factors; Tissue Distribution	1980
Antiarrhythmic effect of lorcainide during chronic treatment. Arzneimittel-Forschung, 1980, Volume: 30, Issue:9 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Drug Resistance; Electrocardiography; Female; Heart Ventricles; Humans; Male; Middle Aged; Piperidines	1980
Pharmacokinetics of lorcainide, a new antiarrhythmic drug, in patients with cardiac rhythm disorders. The American journal of cardiology, 1981, Volume: 48, Issue:1 Topics: Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Female; Humans; Kinetics; Male; Middle Aged; Piperidines; Time Factors	1981
Haemodynamic reactions after intravenous injection of lorcainide hydrochloride in acute myocardial infarction. European journal of cardiology, 1981, Volume: 12, Issue:5 Topics: Anti-Arrhythmia Agents; Benzeneacetamides; Hemodynamics; Humans; Injections, Intravenous; Myocardial Infarction; Piperidines	1981
High-performance liquid chromatographic analysis of lorcainide and its active metabolite, norlorcainide, in human plasma. Journal of chromatography, 1981, May-08, Volume: 223, Issue:2 Topics: Benzeneacetamides; Chromatography, High Pressure Liquid; Humans; Piperidines; Reference Values	1981
[Clinical-electrophysiological study of the effect of lorcainide on induction of ventricular tachycardia (author's transl)]. Zeitschrift fur Kardiologie, 1981, Volume: 70, Issue:7 Topics: Benzeneacetamides; Cardiac Pacing, Artificial; Coronary Disease; Heart Failure; Heart Rate; Piperidines; Tachycardia; Ventricular Fibrillation	1981
Electrophysiological effects of a new antiarrhythmic agent, lorcainide, on the isolated cardiac muscle fiber as compared with disopyramide. Journal of pharmacobio-dynamics, 1980, Volume: 3, Issue:12 Topics: Action Potentials; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Disopyramide; Dose-Response Relationship, Drug; Guinea Pigs; Heart; Heart Conduction System; Heart Rate; In Vitro Techniques; Male; Piperidines; Pyridines; Refractory Period, Electrophysiological	1980
[Preliminary clinical and experimental data on a new anti-arrhythmic drug: lorcainide]. Minerva medica, 1980, Apr-02, Volume: 71, Issue:13 Topics: Adult; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Drug Evaluation; Female; Humans; Male; Middle Aged; Piperidines	1980
Lorcainide -- an anti-arrhythmic agent for ventricular arrhythmias. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Feb-16, Volume: 57, Issue:7 Topics: Adult; Aged; Arrhythmias, Cardiac; Benzeneacetamides; Electrocardiography; Humans; Male; Middle Aged; Myocardial Infarction; Piperidines; Ventricular Fibrillation	1980
Resistant ventricular arrhythmias treated with lorcainide, a new antiarrhythmic drug. Chest, 1980, Volume: 78, Issue:4 Topics: Administration, Oral; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Drug Resistance; Humans; Male; Piperidines	1980
Haemodynamic effects of a single intravenous dose of lorcainide in patients with heart disease. European journal of clinical pharmacology, 1980, Volume: 18, Issue:6 Topics: Adult; Aged; Anti-Arrhythmia Agents; Benzeneacetamides; Blood Pressure; Cardiac Output; Female; Heart; Heart Diseases; Humans; Male; Middle Aged; Myocardial Contraction; Piperidines; Time Factors; Vascular Resistance	1980
[Endocavitary study of Lorcainide (author's transl)]. Revue medicale de Bruxelles, 1980, Volume: 1, Issue:3 Topics: Anti-Arrhythmia Agents; Benzeneacetamides; Electrocardiography; Heart Conduction System; Humans; Piperidines	1980
Electrophysiological effects of lorcainide, a new antiarrhythmic drug. Observations in patients with and without pre-excitation. British heart journal, 1981, Volume: 45, Issue:3 Topics: Adult; Aged; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Cardiac Pacing, Artificial; Electrocardiography; Female; Heart Block; Heart Conduction System; Humans; Male; Middle Aged; Piperidines; Tachycardia	1981
Fatal lorcainide poisoning. Journal of toxicology. Clinical toxicology, 1995, Volume: 33, Issue:2 Topics: Adolescent; Anti-Arrhythmia Agents; Benzeneacetamides; Fatal Outcome; Female; Humans; Piperidines; Poisoning; Suicide	1995
Efficacy of class 1C antiarrhythmic agents in patients with inducible ventricular tachycardia refractory to therapy with class 1A antiarrhythmic drugs. Journal of clinical pharmacology, 1993, Volume: 33, Issue:7 Topics: Adult; Aged; Aged, 80 and over; Anti-Arrhythmia Agents; Benzeneacetamides; Electric Stimulation; Encainide; Female; Flecainide; Humans; Male; Middle Aged; Piperidines; Quinidine; Retrospective Studies; Stroke Volume; Tachycardia, Ventricular	1993
Effects of class I antiarrhythmic drugs on mitochondrial ATPase activity in guinea pig heart preparations. General pharmacology, 1993, Volume: 24, Issue:1 Topics: Adenosine Triphosphatases; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Chemical Phenomena; Chemistry, Physical; Guinea Pigs; In Vitro Techniques; Lidocaine; Mitochondria, Heart; Piperidines; Quinidine	1993
[HPLC method for determination of lorcainide hydrochloride in human serum]. Yao xue xue bao = Acta pharmaceutica Sinica, 1995, Volume: 30, Issue:8 Topics: Adult; Anti-Arrhythmia Agents; Benzeneacetamides; Chromatography, High Pressure Liquid; Humans; Male; Piperidines	1995
Frequency dependent prolongation of effective refractory period by a complex class III antiarrhythmic agent CPU-86017. Acta pharmacologica Sinica, 2001, Volume: 22, Issue:1 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Berberine; Calcium Channel Blockers; Female; Guinea Pigs; Heart Atria; In Vitro Techniques; Male; Papillary Muscles; Phenethylamines; Piperidines; Potassium Channel Blockers; Refractory Period, Electrophysiological; Sulfonamides; Verapamil	2001
Identification of the antiarrhythmic drugs amiodarone and lorcainide as potent H3 histamine receptor inverse agonists. The Journal of pharmacology and experimental therapeutics, 2014, Volume: 348, Issue:1 Topics: Amiodarone; Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Cell Proliferation; Drug Inverse Agonism; HEK293 Cells; Histamine Agonists; Humans; Mice; NIH 3T3 Cells; Piperidines; Rats; Receptors, Histamine H3	2014
Therapeutic fashion and publication bias: the case of anti-arrhythmic drugs in heart attack. Journal of the Royal Society of Medicine, 2015, Volume: 108, Issue:10 Topics: Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Benzeneacetamides; Evidence-Based Medicine; Humans; Myocardial Infarction; Piperidines; Publication Bias	2015
Inhibition of voltage-dependent K European journal of pharmacology, 2021, Aug-05, Volume: 904 Topics: Animals; Anti-Arrhythmia Agents; Benzeneacetamides; Coronary Vessels; Dose-Response Relationship, Drug; Kinetics; Kv1.5 Potassium Channel; Male; Membrane Potentials; Muscle, Smooth, Vascular; Myocytes, Smooth Muscle; Patch-Clamp Techniques; Piperidines; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Rabbits; Shab Potassium Channels	2021