lorazepam and valproic acid

lorazepam has been researched along with valproic acid in 72 studies

Research

Studies (72)

Timeframe	Studies, this research(%)	All Research%
pre-1990	8 (11.11)	18.7374
1990's	10 (13.89)	18.2507
2000's	25 (34.72)	29.6817
2010's	25 (34.72)	24.3611
2020's	4 (5.56)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Strassburg, CP; Tukey, RH	1
Topliss, JG; Yoshida, F	1
Chang, TK; Ensom, MH; Kiang, TK	1
Abraham, MH; Acree, WE; Ibrahim, A	1
Lombardo, F; Obach, RS; Waters, NJ	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Bourgeois, M; Paty, J	1
de Angelis, L	2
Hudson, JI; Keck, PE; McElroy, SL; Pope, HG	1
Bachmann, KA; Forney, RB; Jauregui, L; Martin, M; Nunlee, M; Schwartz, J	1
Calvo, R; Carlos, R; Erill, S	1
Bentley, M; Feely, M; Gent, JP; Haigh, JR	1
Calderazzo, L; Cepeda, C; Naquet, R; Stutzmann, JM; Valin, A	1
Petersen, EN	1
Bleck, TP	1
Petersen, EN; Rasmussen, KJ; Schneider, HH	1
Bennett, JA; Keck, PE; McElroy, SL; Tugrul, KC	1
Bachmann, KA; Jauregui, L	1
Finnerty, M; Levin, Z; Miller, LJ	1
Callahan, AM; Denicoff, K; Frye, MA; George, MS; Ketter, TA; Leverich, GS; Marangell, LB; Pazzaglia, PJ; Post, RM	1
Cavanaugh, JH; Granneman, RG; Samara, EE; Witt, GF	1
Ferrera, PC; Thibodeau, LG	1
Brady, KT; Malcolm, R; Myrick, H	1
Temkin, NR	1
Campbell, T; Hubatch, S; Longo, LP	1
Heo, K; Lee, JK; Lee, SA	1
Augustyns, I; Grossman, F; Ravindran, A; Vieta, E; Yatham, LN	1
Lerner, AJ; Maddux, BN; Sagar, SM; Suarez, JI; Ubogu, EE; Werz, MA	1
Wheless, JW	1
de Angelis, L; Lang, AP	1
Coffey, B	1
Cho, JY; Chung, JY; Jang, IJ; Jung, HR; Kim, JR; Lim, KS; Shin, SG; Yu, KS	1
Capovilla, G; Minicucci, F; Muscas, G; Perucca, E; Tinuper, P; Vigevano, F	1
Rodriguez, LJ	1
Cho, JY; Chung, JY; Jang, IJ; Kim, JR; Lim, KS; Shin, SG; Sohn, DR; Yu, KS	1
Durand, M; Forget, K; Grignon, S; Huppert, T	1
Delima, SI; Golomb, MR; Walsh, LE	1
Dardis, C; Doherty, C; Farid, S	1
Kalita, J; Misra, UK; Nair, PP	1
Kalra, B; Mendhekar, DN; Sekhar, S; Tekur, U	1
Carter, WG; Lauterbach, EC; Norris, BK; Shillcutt, SD	1
Ahir, BK; Pratten, MK	1
LaRoche, SM; Shivdat-Nanhoe, R	1
Sasidaran, K; Singhi, P; Singhi, S	1
Gabriel, S; Pittermann, P; Röschke, J	1
Galimi, R	1
Chou, KR; Chun Tsai, H; Hua Chang, H; Huang, SY; Hung Chi, M; Kuang Yang, Y; Lu, RB; See Chen, P; Tzeng, NS	1
Alldredge, B; Bell, R; Bleck, TP; Brophy, GM; Claassen, J; Glauser, T; LaRoche, SM; Riviello, JJ; Shutter, L; Sperling, MR; Treiman, DM; Vespa, PM	1
Bilici, M; Hariri, A; Ünübol, H; Uz, Y	1
Carlo, S; Castaing-Lespier, PA; Sabaté, N; Santos-Cubiñá, J; Torres-Martin, A; Torres-Rodríguez, A	1
Junewar, V; Rathaur, BP; Verma, R	1
Csomor, PA; Geyer, MA; Huber, T; Preller, KH; Studerus, E; Vollenweider, FX	1
Chang, YH; Chen, KC; Chen, PS; Chen, SL; Hong, JS; Huang, SY; Lee, IH; Lee, SY; Lu, RB; Tzeng, NS; Wang, CL; Wang, LJ; Wang, TY; Yang, YK	1
Barnhorst, A; Xiong, GL	1
Bindu, PS; Mundlamuri, RC; Nagappa, M; Prathyusha, PV; Satishchandra, P; Sinha, S; Subbakrishna, DK; Taly, AB; Umamaheswara Rao, GS	1
Kalita, J; Misra, UK	1
Dziodzio, JT; Fontaine, GV; Fraser, GL; Gagnon, DJ; Lerwick, PA; Lucas, FL; Miller, RR; Riker, RR; Sihler, KC; Smith, KE	1
Erkuran, HÖ; Kutlu, A; Önen, Ö	1
Bc, M; Chatterjee, SS; Das, S; Kartha, A; Purushothaman, ST; Rajan, V	1
Dubey, D; Kalita, J; Misra, UK	1
Bedoya, C; Caraballo, RH; Chacón, S; Fasulo, L	1
Bharath, RD; Bindu, PS; Mundlamuri, RC; Nagappa, M; Nene, D; Prathyusha, PV; Raghavendra, K; Saini, J; Satishchandra, P; Sinha, S; Taly, AB; Thennarasu, K	1
Hayashi, T; Noguchi, Y; Tachi, T; Takaoka, M; Teramachi, H	1
de Neeling, M; van Paesschen, W	1
de Goede, AA; Doll, RJ; Groeneveld, GJ; Heuberger, JAAC; Otto, ME; Ruijs, TQ; van Putten, MJAM; Ziagkos, D	1
Hume, AL; Lawal, OD; Meador, KJ; Wen, X	1

Reviews

10 review(s) available for lorazepam and valproic acid

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016
[Myoclonus induced by some benzodiazepines in the Papio papio. Comparison with myoclonus induced by intermittent light stimulation (author's transl)]. Revue d'electroencephalographie et de neurophysiologie clinique, 1982, Volume: 12, Issue:1 Topics: Allylglycine; Animals; Anti-Anxiety Agents; Apomorphine; Diazepam; Levodopa; Lorazepam; Myoclonus; Papio; Photic Stimulation; Serotonin; Valproic Acid	1982
Therapy for status epilepticus. Clinical neuropharmacology, 1983, Volume: 6, Issue:4 Topics: Acetazolamide; Anesthesia; Anticonvulsants; Barbiturates; Chlormethiazole; Clonazepam; Diazepam; Ethosuximide; Humans; Lidocaine; Lorazepam; Paraldehyde; Phenobarbital; Phenytoin; Status Epilepticus; Valproic Acid	1983
The place of anticonvulsant therapy in bipolar illness. Psychopharmacology, 1996, Volume: 128, Issue:2 Topics: Affect; Anticonvulsants; Bipolar Disorder; Calcium Channel Blockers; Carbamazepine; Clonazepam; Drug Therapy, Combination; Humans; Lorazepam; Valproic Acid	1996
Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials. Epilepsia, 2001, Volume: 42, Issue:4 Topics: Anticonvulsants; Brain Diseases; Brain Injuries; Carbamazepine; Controlled Clinical Trials as Topic; Diazepam; Epilepsy; Humans; Lorazepam; Models, Statistical; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Risk; Seizures; Treatment Outcome; Valproic Acid	2001
Acute management of seizures in the syndromes of idiopathic generalized epilepsies. Epilepsia, 2003, Volume: 44 Suppl 2 Topics: Acute Disease; Adolescent; Adult; Anticonvulsants; Clonazepam; Comorbidity; Drug Administration Schedule; Epilepsies, Myoclonic; Epilepsy, Absence; Epilepsy, Generalized; Epilepsy, Tonic-Clonic; Humans; Infusions, Intravenous; Lorazepam; Practice Guidelines as Topic; Status Epilepticus; Syndrome; Valproic Acid	2003
Management of acute seizure and status epilepticus in pediatric emergency. Indian journal of pediatrics, 2012, Volume: 79, Issue:4 Topics: Anesthesia, Intravenous; Anticonvulsants; Benzodiazepines; Child; Child, Preschool; Combined Modality Therapy; Cross-Sectional Studies; Developing Countries; Dose-Response Relationship, Drug; Emergency Service, Hospital; Epilepsy; Humans; India; Infant; Infusions, Intravenous; Intensive Care Units, Pediatric; Levetiracetam; Lorazepam; Phenytoin; Piracetam; Seizures; Status Epilepticus; Thiopental; Valproic Acid	2012
Nonconvulsive status epilepticus in pediatric populations: diagnosis and management. Minerva pediatrica, 2012, Volume: 64, Issue:3 Topics: Acetazolamide; Anticonvulsants; Benzodiazepines; Child; Clobazam; Electroencephalography; Humans; Lorazepam; Status Epilepticus; Treatment Outcome; Valproic Acid	2012

Trials

15 trial(s) available for lorazepam and valproic acid

Article	Year
Valproate in the treatment of acute mania. A placebo-controlled study. Archives of general psychiatry, 1991, Volume: 48, Issue:1 Topics: Acute Disease; Adolescent; Adult; Aged; Bipolar Disorder; Double-Blind Method; Drug Administration Schedule; Female; Humans; Lorazepam; Male; Middle Aged; Placebos; Psychiatric Status Rating Scales; Valproic Acid	1991
Valproate oral loading in the treatment of acute mania. The Journal of clinical psychiatry, 1993, Volume: 54, Issue:8 Topics: Acute Disease; Administration, Oral; Adult; Bipolar Disorder; Drug Therapy, Combination; Female; Hospitalization; Humans; Lorazepam; Male; Prospective Studies; Psychiatric Status Rating Scales; Valproic Acid	1993
Use of single sample clearance estimates of cytochrome P450 substrates to characterize human hepatic CYP status in vivo. Xenobiotica; the fate of foreign compounds in biological systems, 1993, Volume: 23, Issue:3 Topics: Administration, Oral; Adult; Antipyrine; Aryl Hydrocarbon Hydroxylases; Carbamazepine; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Ethosuximide; Humans; Liver; Lorazepam; Male; Oxidoreductases, N-Demethylating; Phenobarbital; Phenytoin; Quinidine; Rifampin; Smoking; Theophylline; Valproic Acid	1993
Effect of valproate on the pharmacokinetics and pharmacodynamics of lorazepam. Journal of clinical pharmacology, 1997, Volume: 37, Issue:5 Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Double-Blind Method; Drug Interactions; Humans; Lorazepam; Male; Valproic Acid	1997
Divalproex in the treatment of alcohol withdrawal. The American journal of drug and alcohol abuse, 2000, Volume: 26, Issue:1 Topics: Adult; Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Anticonvulsants; Female; Humans; Lorazepam; Male; Middle Aged; Neurologic Examination; Treatment Outcome; Valproic Acid	2000
Divalproex sodium (Depakote) for alcohol withdrawal and relapse prevention. Journal of addictive diseases, 2002, Volume: 21, Issue:2 Topics: Adult; Alcohol Withdrawal Delirium; Alcoholism; Ambulatory Care; Anti-Anxiety Agents; Anticonvulsants; Chlordiazepoxide; Female; Follow-Up Studies; Humans; Lorazepam; Male; Middle Aged; Patient Admission; Pilot Projects; Recurrence; Substance Abuse Treatment Centers; Treatment Outcome; Valproic Acid	2002
Mood stabilisers plus risperidone or placebo in the treatment of acute mania. International, double-blind, randomised controlled trial. The British journal of psychiatry : the journal of mental science, 2003, Volume: 182 Topics: Adult; Aged; Antimanic Agents; Antipsychotic Agents; Basal Ganglia Diseases; Bipolar Disorder; Brief Psychiatric Rating Scale; Double-Blind Method; Drug Administration Schedule; Drug Therapy, Combination; Female; Humans; Lithium Compounds; Lorazepam; Male; Middle Aged; Psychiatric Status Rating Scales; Risperidone; Treatment Outcome; Treatment Refusal; Valproic Acid	2003
Pharmacokinetic and pharmacodynamic interaction of lorazepam and valproic acid in relation to UGT2B7 genetic polymorphism in healthy subjects. Clinical pharmacology and therapeutics, 2008, Volume: 83, Issue:4 Topics: Adult; Anticonvulsants; Area Under Curve; Female; Glucuronosyltransferase; Humans; Lorazepam; Male; Polymorphism, Genetic; Psychometrics; Psychomotor Performance; Valproic Acid	2008
Efficacy of sodium valproate and haloperidol in the management of acute mania: a randomized open-label comparative study. Journal of clinical pharmacology, 2010, Volume: 50, Issue:6 Topics: Adolescent; Adult; Antimanic Agents; Bipolar Disorder; Dyskinesia, Drug-Induced; Female; Haloperidol; Humans; Injections, Intramuscular; Injections, Intravenous; Lorazepam; Male; Middle Aged; Severity of Illness Index; Valproic Acid	2010
Correlation of plasma brain-derived neurotrophic factor and metabolic profiles in drug-naïve patients with bipolar II disorder after a twelve-week pharmacological intervention. Acta psychiatrica Scandinavica, 2015, Volume: 131, Issue:2 Topics: Adult; Affect; Bipolar Disorder; Body Mass Index; Brain-Derived Neurotrophic Factor; Cholesterol; Female; Fluoxetine; Humans; Linear Models; Lipoproteins, LDL; Longitudinal Studies; Lorazepam; Male; Metabolic Syndrome; Psychiatric Status Rating Scales; Treatment Outcome; Valproic Acid	2015
Management of generalised convulsive status epilepticus (SE): A prospective randomised controlled study of combined treatment with intravenous lorazepam with either phenytoin, sodium valproate or levetiracetam--Pilot study. Epilepsy research, 2015, Volume: 114 Topics: Adolescent; Adult; Aged; Anticonvulsants; Drug Therapy, Combination; Electroencephalography; Epilepsy, Generalized; Female; Follow-Up Studies; Humans; Injections, Intravenous; Levetiracetam; Lorazepam; Male; Middle Aged; Phenytoin; Pilot Projects; Piracetam; Prognosis; Prospective Studies; Status Epilepticus; Treatment Outcome; Valproic Acid; Young Adult	2015
A comparison of four antiepileptic drugs in status epilepticus: experience from India. The International journal of neuroscience, 2016, Volume: 126, Issue:11 Topics: Adolescent; Adult; Aged; Anticonvulsants; Child; Child, Preschool; Female; Humans; India; Infant; Levetiracetam; Lorazepam; Male; Middle Aged; Outcome Assessment, Health Care; Phenytoin; Piracetam; Status Epilepticus; Valproic Acid; Young Adult	2016
Comparison of lacosamide versus sodium valproate in status epilepticus: A pilot study. Epilepsy & behavior : E&B, 2017, Volume: 76 Topics: Acetamides; Administration, Intravenous; Adolescent; Adult; Aged; Aged, 80 and over; Anticonvulsants; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Lacosamide; Lorazepam; Male; Middle Aged; Pilot Projects; Seizures; Status Epilepticus; Treatment Outcome; Valproic Acid; Young Adult	2017
Comparing the efficacy of sodium valproate and levetiracetam following initial lorazepam in elderly patients with generalized convulsive status epilepticus (GCSE): A prospective randomized controlled pilot study. Seizure, 2019, Volume: 65 Topics: Aged; Aged, 80 and over; Aging; Anticonvulsants; Dose-Response Relationship, Drug; Electroencephalography; Female; Humans; Levetiracetam; Logistic Models; Lorazepam; Male; Middle Aged; Pilot Projects; Prospective Studies; Single-Blind Method; Status Epilepticus; Treatment Outcome; Valproic Acid	2019
Transcranial magnetic stimulation as biomarker of excitability in drug development: A randomized, double-blind, placebo-controlled, cross-over study. British journal of clinical pharmacology, 2022, Volume: 88, Issue:6 Topics: Biomarkers; Cross-Over Studies; Electroencephalography; Humans; Levetiracetam; Lorazepam; Male; Pharmaceutical Preparations; Transcranial Magnetic Stimulation; Valproic Acid	2022

Other Studies

47 other study(ies) available for lorazepam and valproic acid

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs. European journal of medicinal chemistry, 2008, Volume: 43, Issue:3 Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization	2008
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility	2010
[Risk of psychotropic drug potentiation by dipropylacetamide (16 cases)]. L'Encephale, 1978, Volume: 4, Issue:3 Topics: Adult; Aged; Anticonvulsants; Antidepressive Agents; Cognition Disorders; Drug Synergism; Drug Therapy, Combination; Female; Follow-Up Studies; Humans; Lorazepam; Male; Middle Aged; Movement Disorders; Serotonin; Valproic Acid	1978
The anxiogenic-like effects of pentylenetetrazole in mice treated chronically with carbamazepine or valproate. Methods and findings in experimental and clinical pharmacology, 1992, Volume: 14, Issue:10 Topics: Animals; Anxiety; Behavior, Animal; Carbamazepine; Female; Lorazepam; Mice; Pentylenetetrazole; Valproic Acid	1992
The use of single sample clearance estimates to probe hepatic drug metabolism: handprinting the influence of cigarette smoking on human hepatic drug metabolism. Xenobiotica; the fate of foreign compounds in biological systems, 1990, Volume: 20, Issue:5 Topics: Antipyrine; Carbamazepine; Glucuronosyltransferase; Humans; Liver; Lorazepam; Male; Metabolic Clearance Rate; Microbodies; Microsomes, Liver; Mixed Function Oxygenases; Oxidoreductases; Pharmaceutical Preparations; Polycyclic Compounds; Quinidine; Smoking; Theophylline; Valproic Acid	1990
Differential effects of valproic acid on the serum protein binding of lorazepam and diazepam. International journal of clinical pharmacology research, 1986, Volume: 6, Issue:3 Topics: Blood Proteins; Charcoal; Diazepam; Humans; In Vitro Techniques; Lorazepam; Protein Binding; Valproic Acid	1986
Benzodiazepine cross-tolerance in mice extends to sodium valproate. European journal of pharmacology, 1986, Aug-22, Volume: 128, Issue:1-2 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Benzodiazepinones; Clobazam; Clonazepam; Diazepam; Drug Tolerance; Lorazepam; Male; Mice; Pentylenetetrazole; Phenobarbital; Valproic Acid	1986
DMCM: a potent convulsive benzodiazepine receptor ligand. European journal of pharmacology, 1983, Oct-14, Volume: 94, Issue:1-2 Topics: Animals; Carbolines; Convulsants; Diazepam; Drug Interactions; Female; Indoles; Lorazepam; Male; Mice; Pentylenetetrazole; Rats; Rats, Inbred Strains; Receptors, Cell Surface; Receptors, GABA-A; Seizures; Valproic Acid	1983
Sodium valproate exerts anti-conflict activity in rats without any concomitant rise in forebrain GABA level. Life sciences, 1981, Nov-23, Volume: 29, Issue:21 Topics: Aminocaproates; Aminooxyacetic Acid; Animals; Behavior, Animal; Brain; Conflict, Psychological; Dose-Response Relationship, Drug; Electroshock; gamma-Aminobutyric Acid; Lorazepam; Male; Rats; Valproic Acid; Vigabatrin	1981
Acute manic episodes in pregnancy. The American journal of psychiatry, 1996, Volume: 153, Issue:2 Topics: Adult; Bipolar Disorder; Chlorpromazine; Comorbidity; Diabetes Mellitus, Type 1; Drug Therapy, Combination; Electroconvulsive Therapy; Female; Haloperidol; Humans; Lorazepam; Pregnancy; Pregnancy Complications; Valproic Acid	1996
Effects of valproate and lorazepam on experimental anxiety: tolerance, withdrawal, and role of clonidine. Pharmacology, biochemistry, and behavior, 1995, Volume: 52, Issue:2 Topics: Adrenergic alpha-Agonists; Animals; Anti-Anxiety Agents; Anxiety; Avoidance Learning; Clonidine; Drug Tolerance; Female; Injections, Intraperitoneal; Lorazepam; Mice; Substance Withdrawal Syndrome; Valproic Acid	1995
Nonconvulsive status epilepticus. The American journal of emergency medicine, 1997, Volume: 15, Issue:7 Topics: Anticonvulsants; Dizziness; Electroencephalography; Emergency Service, Hospital; Epilepsy, Tonic-Clonic; Humans; Lorazepam; Male; Middle Aged; Neurologic Examination; Phenobarbital; Primidone; Status Epilepticus; Valproic Acid	1997
Coma probably induced by lorazepam-valproate interaction. Seizure, 2002, Volume: 11, Issue:2 Topics: Adult; Anticonvulsants; Coma; Drug Interactions; Epilepsy; Female; Humans; Lorazepam; Valproic Acid	2002
Ketamine for refractory status epilepticus: a case of possible ketamine-induced neurotoxicity. Epilepsy & behavior : E&B, 2003, Volume: 4, Issue:1 Topics: Adult; Anticonvulsants; Atrophy; Brain; Electroencephalography; Excitatory Amino Acid Antagonists; Humans; Ketamine; Lorazepam; Magnetic Resonance Imaging; Male; Neurotoxicity Syndromes; Phenytoin; Receptors, N-Methyl-D-Aspartate; Severity of Illness Index; Status Epilepticus; Valproic Acid	2003
Experimental anxiety and antiepileptics: the effects of valproate and vigabatrin in the mirrored chamber test. Methods and findings in experimental and clinical pharmacology, 2003, Volume: 25, Issue:4 Topics: Animals; Anti-Anxiety Agents; Anticonvulsants; Anxiety; Conflict, Psychological; Disease Models, Animal; Dose-Response Relationship, Drug; Escape Reaction; Female; Injections, Intraperitoneal; Lorazepam; Maze Learning; Mice; Piperazines; Receptor, Serotonin, 5-HT1B; Receptor, Serotonin, 5-HT2C; Receptors, Serotonin; Serotonin Receptor Agonists; Valproic Acid; Vigabatrin	2003
Clinical case presentation: therapeutic challenges in adolescent-onset bipolar disorder. Journal of child and adolescent psychopharmacology, 2003,Winter, Volume: 13, Issue:4 Topics: Adolescent; Aggression; Anti-Anxiety Agents; Antimanic Agents; Antipsychotic Agents; Bipolar Disorder; Clonazepam; Diagnosis, Differential; Education; Family; GABA Modulators; Haloperidol; Hospitalization; Humans; Irritable Mood; Lithium; Lorazepam; Male; Piperazines; Psychiatric Status Rating Scales; Sexual Behavior; Thiazoles; Valproic Acid	2003
Effect of the UGT2B15 genotype on the pharmacokinetics, pharmacodynamics, and drug interactions of intravenous lorazepam in healthy volunteers. Clinical pharmacology and therapeutics, 2005, Volume: 77, Issue:6 Topics: Adult; Drug Interactions; Enzyme Inhibitors; Female; Genotype; Glucuronosyltransferase; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lorazepam; Male; Polymorphism, Genetic; Rifampin; Valproic Acid	2005
Treatment of status epilepticus in adults: guidelines of the Italian League against Epilepsy. Epilepsia, 2006, Volume: 47 Suppl 5 Topics: Adult; Age Factors; Anesthesia, General; Anticonvulsants; Benzodiazepines; Humans; International Agencies; Italy; Lorazepam; Phenobarbital; Phenytoin; Practice Guidelines as Topic; Propofol; Secondary Prevention; Status Epilepticus; Thiopental; Valproic Acid	2006
A closer look: the benefits and effectiveness of cognitive behavioral therapy on a female-specific unit for treatment of bipolar disorder. Issues in mental health nursing, 2007, Volume: 28, Issue:5 Topics: Adult; Bipolar Disorder; Cognitive Behavioral Therapy; Female; Health Knowledge, Attitudes, Practice; Health Services Needs and Demand; Hispanic or Latino; Hospital Units; Hospitalization; Humans; Lorazepam; New York; Patient Education as Topic; Psychotropic Drugs; Recurrence; Thinking; Treatment Outcome; Treatment Refusal; Valproic Acid; Women; Women's Health Services	2007
Increased left prefrontal activation during staring/mutism episodes in a patient with resistant catatonic schizophrenia: a near infrared spectroscopy study. Cognitive and behavioral neurology : official journal of the Society for Behavioral and Cognitive Neurology, 2008, Volume: 21, Issue:1 Topics: Adult; Attention; Awareness; Catalepsy; Clozapine; Combined Modality Therapy; Dominance, Cerebral; Drug Resistance; Electroconvulsive Therapy; Fixation, Ocular; Humans; Image Processing, Computer-Assisted; Imaging, Three-Dimensional; Lorazepam; Male; Mutism; Oxyhemoglobins; Prefrontal Cortex; Regional Blood Flow; Schizophrenia, Catatonic; Spectroscopy, Near-Infrared; Valproic Acid	2008
Simultaneous toxicities in a child on multiple anticonvulsants. Journal of child neurology, 2008, Volume: 23, Issue:9 Topics: Anticonvulsants; Bone Marrow; Bone Marrow Diseases; Chemical and Drug Induced Liver Injury; Child, Preschool; Drug Synergism; Drug Therapy, Combination; Epilepsy; Female; Humans; Lamotrigine; Liver; Liver Diseases; Lorazepam; Parainfluenza Virus 3, Human; Paramyxoviridae Infections; Phenytoin; Status Epilepticus; Triazines; Valproic Acid	2008
Re: New lessons: classic treatments in convulsive status epilepticus. Irish medical journal, 2008, Volume: 101, Issue:2 Topics: Anticonvulsants; Benzodiazepines; Diazepam; Humans; Lorazepam; Phenytoin; Status Epilepticus; Valproic Acid	2008
Status epilepticus in central nervous system infections: an experience from a developing country. The American journal of medicine, 2008, Volume: 121, Issue:7 Topics: Adolescent; Adult; Aged; Anticonvulsants; Central Nervous System Infections; Developing Countries; Diazepam; Drug Resistance; Electroencephalography; Female; Hospitals, Teaching; Humans; India; Lorazepam; Magnetic Resonance Imaging; Male; Midazolam; Middle Aged; Phenytoin; Prospective Studies; Status Epilepticus; Valproic Acid	2008
Catatonia and CPK elevation in neurosyphilis: role of plural pharmacodynamic mechanisms. Psychopharmacology bulletin, 2009, Volume: 42, Issue:4 Topics: Adult; Aripiprazole; Catatonia; Creatine Kinase; Dose-Response Relationship, Drug; Doxycycline; Humans; Lorazepam; Male; Neurosyphilis; Piperazines; Quinolones; Temazepam; Valproic Acid	2009
Association of anxiolytic drugs diazepam and lorazepam, and the antiepileptic valproate, with heart defects--effects on cardiomyocytes in micromass (MM) and embryonic stem cell culture. Reproductive toxicology (Elmsford, N.Y.), 2011, Volume: 31, Issue:1 Topics: Animals; Anti-Anxiety Agents; Cell Line; Cell Survival; Chick Embryo; Chickens; Diazepam; Embryo, Mammalian; Embryonic Stem Cells; Heart Rate; Lorazepam; Mice; Myocardial Contraction; Myocytes, Cardiac; Proteins; Valproic Acid	2011
Subacute encephalopathy and seizures in alcoholics (SESA) presenting with non-convulsive status epilepticus. Seizure, 2011, Volume: 20, Issue:6 Topics: Acetamides; Alcohol Withdrawal Seizures; Alcoholism; Anticonvulsants; Brain Diseases; Confusion; Diffusion Magnetic Resonance Imaging; Electroencephalography; Female; Humans; Lacosamide; Lorazepam; Middle Aged; Neurologic Examination; Paresis; Patient Compliance; Phenytoin; Seizures; Status Epilepticus; Tomography, X-Ray Computed; Valproic Acid	2011
[Delirium caused by nonconvulsive status epilepticus]. Psychiatrische Praxis, 2012, Volume: 39, Issue:4 Topics: Affect; Aged; Anticonvulsants; Antipsychotic Agents; Brain Edema; Confusion; Delirium; Dibenzothiazepines; Drug Substitution; Drug Therapy, Combination; Electroencephalography; Frontal Lobe; Fructose; Humans; Lorazepam; Magnetic Resonance Imaging; Male; Mental Status Schedule; Neurologic Examination; Quetiapine Fumarate; Referral and Consultation; Signal Processing, Computer-Assisted; Status Epilepticus; Topiramate; Valproic Acid	2012
The prevalence of metabolic syndrome in drug-naïve bipolar II disorder patients before and after twelve week pharmacological intervention. Journal of affective disorders, 2013, Mar-20, Volume: 146, Issue:1 Topics: Adult; Antimanic Agents; Bipolar Disorder; Body Mass Index; Diagnostic and Statistical Manual of Mental Disorders; Female; Fluoxetine; Follow-Up Studies; Humans; Lorazepam; Male; Metabolic Syndrome; Prevalence; Treatment Outcome; Valproic Acid; Young Adult	2013
Treatment of status epilepticus: an international survey of experts. Neurocritical care, 2013, Volume: 18, Issue:2 Topics: Administration, Intravenous; Adult; Anticonvulsants; Child; Consensus; Expert Testimony; Humans; Hypnotics and Sedatives; Levetiracetam; Lorazepam; Midazolam; Pentobarbital; Phenytoin; Piracetam; Propofol; Societies, Medical; Status Epilepticus; Surveys and Questionnaires; Valproic Acid	2013
Stupor due to possible interaction between Lorazepam and valproic acid: report of two cases. Turk psikiyatri dergisi = Turkish journal of psychiatry, 2012,Winter, Volume: 23, Issue:4 Topics: Anti-Anxiety Agents; Anticonvulsants; Diagnosis, Differential; Drug Interactions; Drug Therapy, Combination; Female; Humans; Lorazepam; Psychotic Disorders; Stupor; Valproic Acid	2012
Exacerbation of mood symptoms associated to primary and secondary carnitine deficiency: a case report. Boletin de la Asociacion Medica de Puerto Rico, 2013, Volume: 105, Issue:3 Topics: Adult; Antidepressive Agents; Antimanic Agents; Attention Deficit Disorder with Hyperactivity; Benzodiazepines; Carnitine; Citalopram; Depressive Disorder; Disruptive, Impulse Control, and Conduct Disorders; Drug Substitution; Drug Therapy, Combination; Humans; Hyperammonemia; Ketoglutarate Dehydrogenase Complex; Lorazepam; Male; Mood Disorders; Olanzapine; Organic Cation Transport Proteins; Solute Carrier Family 22 Member 5; Valproic Acid	2013
An atypical case of neuroleptic malignant syndrome precipitated by valproate. BMJ case reports, 2014, Mar-06, Volume: 2014 Topics: Anticonvulsants; Antipsychotic Agents; Benzodiazepines; Benzothiazoles; Dopamine Agonists; Drug Therapy, Combination; Female; Fluid Therapy; Humans; Levetiracetam; Lorazepam; Middle Aged; Neuroleptic Malignant Syndrome; Olanzapine; Piracetam; Pramipexole; Psychotic Disorders; Valproic Acid	2014
Influence of aripiprazole, risperidone, and amisulpride on sensory and sensorimotor gating in healthy 'low and high gating' humans and relation to psychometry. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology, 2014, Volume: 39, Issue:10 Topics: Acoustic Stimulation; Amisulpride; Antipsychotic Agents; Aripiprazole; Auditory Perception; Benzhydryl Compounds; Brain; Double-Blind Method; Electroencephalography; Electromyography; Humans; Lorazepam; Male; Modafinil; Piperazines; Prepulse Inhibition; Psychometrics; Psychotropic Drugs; Quinolones; Risperidone; Sensory Gating; Sulpiride; Valproic Acid; Young Adult	2014
Pulmonary embolism in a psychiatric patient. The American journal of psychiatry, 2014, Nov-01, Volume: 171, Issue:11 Topics: Adult; Aggression; Antipsychotic Agents; Autopsy; Benzodiazepines; Bipolar Disorder; Catatonia; Death, Sudden; Female; Humans; Hypothyroidism; Incidence; Lorazepam; Obesity; Olanzapine; Ovarian Neoplasms; Patient Admission; Patient Transfer; Pulmonary Embolism; Restraint, Physical; Risk; Valproic Acid; Venous Thrombosis	2014
Valproate for agitation in critically ill patients: A retrospective study. Journal of critical care, 2017, Volume: 37 Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Delirium; Dexmedetomidine; Female; Fentanyl; GABA Agents; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Psychomotor Agitation; Retrospective Studies; Valproic Acid	2017
Treating an Adolescent with Long QT Syndrome for Bipolar Disorder: A Case Presentation. Psychopharmacology bulletin, 2017, 01-26, Volume: 47, Issue:1 Topics: Adolescent; Bipolar Disorder; Female; Humans; Long QT Syndrome; Lorazepam; Risperidone; Valproic Acid	2017
Oral Asenapine overdose leading to Neuroleptic Malignant Syndrome (NMS). Asian journal of psychiatry, 2017, Volume: 30 Topics: Administration, Oral; Adult; Antipsychotic Agents; Bromocriptine; Diagnosis, Differential; Dibenzocycloheptenes; Dopamine Agonists; Drug Overdose; Fluid Therapy; GABA Modulators; Heterocyclic Compounds, 4 or More Rings; Humans; Lorazepam; Male; Neuroleptic Malignant Syndrome; Valproic Acid	2017
De novo absence status epilepticus in three paediatric patients: a new idiopathic epilepsy syndrome? Epileptic disorders : international epilepsy journal with videotape, 2018, Dec-01, Volume: 20, Issue:6 Topics: Anticonvulsants; Brain; Child; Child, Preschool; Electroencephalography; Epilepsy, Absence; Female; Humans; Lorazepam; Male; Status Epilepticus; Valproic Acid	2018
Antiepileptic combination therapy with Stevens-Johnson syndrome and toxic epidermal necrolysis: Analysis of a Japanese pharmacovigilance database. Epilepsia, 2020, Volume: 61, Issue:9 Topics: Anticonvulsants; Carbamazepine; Clobazam; Clonazepam; Databases, Factual; Drug Therapy, Combination; Epilepsy; Gabapentin; Humans; Japan; Lacosamide; Lamotrigine; Levetiracetam; Lorazepam; Pharmacovigilance; Phenytoin; Stevens-Johnson Syndrome; Valproic Acid	2020
Stupor in a catatonic patient due to an interaction between high-dose lorazepam and valproic acid: a case report. Acta neurologica Belgica, 2021, Volume: 121, Issue:4 Topics: Adult; Anti-Anxiety Agents; Antimanic Agents; Catatonia; Drug Interactions; Female; Humans; Lorazepam; Psychotic Disorders; Stupor; Valproic Acid	2021
Utilization of Antiseizure Medications in Women of Childbearing Age With Epilepsy and Nonepilepsy Indications: A Retrospective Cohort Study. Neurology, 2023, 09-05, Volume: 101, Issue:10 Topics: Anticonvulsants; Clonazepam; Diazepam; Epilepsy; Female; Gabapentin; Humans; Lamotrigine; Lorazepam; Retrospective Studies; Topiramate; Valproic Acid	2023