lorazepam and naloxone

lorazepam has been researched along with naloxone in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's8 (47.06)29.6817
2010's6 (35.29)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Coassolo, P; Lavé, T; Schneider, G1
Strassburg, CP; Tukey, RH1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY1
Chang, TK; Ensom, MH; Kiang, TK1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Greenwald, MK; Stitzer, ML1
Bloom, K; Liebl, MG; Mixides, G1
Martin, HA1
Williams, BN; Yuan, W1
Alladio, E; Leardi, R; Pirro, V; Salomone, A; Vincenti, M1
Bailey, AM; Baum, RA; Horn, K; Justice, SN; Lewis, T; Morizio, K; Schultz, A; Weant, K1
Docci, L; Fowler, S; Krähenbühl, S; Parrott, N; Umehara, K1

Reviews

4 review(s) available for lorazepam and naloxone

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Review of Intranasally Administered Medications for Use in the Emergency Department.
    The Journal of emergency medicine, 2017, Volume: 53, Issue:1

    Topics: Administration, Intranasal; Anesthetics, Dissociative; Anticonvulsants; Antidotes; Antipsychotic Agents; Dexmedetomidine; Emergency Service, Hospital; Fentanyl; Flumazenil; Haloperidol; Humans; Hydromorphone; Hypnotics and Sedatives; Ketamine; Lorazepam; Midazolam; Naloxone; Narcotic Antagonists; Narcotics

2017

Trials

1 trial(s) available for lorazepam and naloxone

ArticleYear
Butorphanol agonist effects and acute physical dependence in opioid abusers: comparison with morphine.
    Drug and alcohol dependence, 1998, Dec-01, Volume: 53, Issue:1

    Topics: Adult; Arousal; Brain; Butorphanol; Dose-Response Relationship, Drug; Double-Blind Method; Euphoria; Heroin Dependence; Humans; Hypnotics and Sedatives; Lorazepam; Male; Morphine; Morphine Dependence; Naloxone; Narcotic Antagonists; Opioid-Related Disorders; Receptors, Opioid, kappa; Receptors, Opioid, mu; Substance Withdrawal Syndrome

1998

Other Studies

12 other study(ies) available for lorazepam and naloxone

ArticleYear
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
    Journal of medicinal chemistry, 1999, Dec-16, Volume: 42, Issue:25

    Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats

1999
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Enteral administration of naloxone for treatment of opioid-associated intragastric feeding intolerance.
    Pharmacotherapy, 2004, Volume: 24, Issue:2

    Topics: Adult; Catheters, Indwelling; Cross Infection; Drug Administration Schedule; Enteral Nutrition; Fatal Outcome; Female; Food Hypersensitivity; Gastric Emptying; Gastrointestinal Motility; Humans; Infusions, Intravenous; Intubation, Gastrointestinal; Lorazepam; Morphine; Naloxone; Narcotics; Pregnancy; Respiratory Distress Syndrome; Respiratory Insufficiency; Time Factors

2004
The possible consequences of combining Lorazepam and buprenorphine/naloxone: a case review.
    Journal of emergency nursing, 2011, Volume: 37, Issue:2

    Topics: Adult; Anti-Anxiety Agents; Buprenorphine; Drug Interactions; Female; Humans; Intubation, Intratracheal; Lorazepam; Naloxone; Narcotic Antagonists; Respiratory Insufficiency

2011
Interactions among benzodiazepine and buprenorphine/naloxone.
    Journal of emergency nursing, 2012, Volume: 38, Issue:1

    Topics: Anti-Anxiety Agents; Buprenorphine; Female; Humans; Lorazepam; Naloxone; Narcotic Antagonists; Respiratory Insufficiency

2012
Chemometric approach to open validation protocols: Prediction of validation parameters in multi-residue ultra-high performance liquid chromatography-tandem mass spectrometry methods.
    Analytica chimica acta, 2015, Jun-09, Volume: 878

    Topics: Chromatography, High Pressure Liquid; Humans; Hypnotics and Sedatives; Illicit Drugs; Least-Squares Analysis; Limit of Detection; Lorazepam; Naloxone; Narcotic Antagonists; Tandem Mass Spectrometry; Validation Studies as Topic

2015
Construction and Verification of Physiologically Based Pharmacokinetic Models for Four Drugs Majorly Cleared by Glucuronidation: Lorazepam, Oxazepam, Naloxone, and Zidovudine.
    The AAPS journal, 2020, 10-08, Volume: 22, Issue:6

    Topics: Administration, Intravenous; Administration, Oral; Adolescent; Adult; Aged; Cell Culture Techniques; Cells, Cultured; Coculture Techniques; Datasets as Topic; Female; Glucuronides; Glucuronosyltransferase; Hepatocytes; Humans; Intestines; Kidney; Liver; Lorazepam; Male; Metabolic Clearance Rate; Microsomes, Liver; Middle Aged; Models, Biological; Naloxone; Oxazepam; Young Adult; Zidovudine

2020