lorazepam has been researched along with midazolam in 181 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 15 (8.29) | 18.7374 |
| 1990's | 38 (20.99) | 18.2507 |
| 2000's | 55 (30.39) | 29.6817 |
| 2010's | 58 (32.04) | 24.3611 |
| 2020's | 15 (8.29) | 2.80 |
| Authors | Studies |
|---|---|
| Damron, DS; Gaivin, RJ; Murray, PA; Perez, DM; Waugh, DJ | 1 |
| Coassolo, P; Lavé, T; Schneider, G | 1 |
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 1 |
| Abraham, MH; Acree, WE; Ibrahim, A | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Loeffler, PM | 1 |
| Aguilera, L; Calvo, R; Martínez-Jorda, R; Rodríguez-Sasiaín, JM; Suárez, E | 1 |
| Daubländer, M; Lipp, M | 1 |
| Doenicke, A; Greim, M; Juhl, G; Rampf, U; Suttmann, H | 1 |
| Joubert, JJ; Roelofse, JA; van der Bijl, P; van Zyl, JF | 1 |
| de Haan, P; Rettig, HC; von Leeuwen, L; Zuurmond, WW | 1 |
| Chauvin, M; Costes, H; Duvaldestin, P; Guirimand, F; Lebrault, C | 1 |
| Klotz, U | 1 |
| Bixler, EO; Jacoby, JA; Kales, A; Kales, JD; Soldatos, CR | 1 |
| Kylmämaa, T; Mattila, MA; Salmela, J; Väänänen, A | 1 |
| Levy, L; Pandit, SK | 1 |
| Lorizio, A; Salsa, F | 1 |
| Aaltonen, L; Aantaa, E; Kanto, J; Salonen, M | 1 |
| Greenblatt, DJ; Knüchel, M; Ochs, HR | 1 |
| Dudkiewicz, J; Misterek, K | 1 |
| Bautz, G; Colburn, WA; Horst, WD; Jack, ML; O'Brien, RA; Spirt, NM; Zanko, M | 1 |
| Breimer, DD; Jochemsen, R | 1 |
| Korttila, K | 1 |
| Doenicke, A | 1 |
| Mitchell, PF | 1 |
| Bonin, JD; de Jong, RH | 1 |
| Hoey, LL; Solberg, CL; Vance-Bryan, K | 1 |
| Comunale, ME; Haering, JM; Maslow, AD; Robertson, LK; Shorten, GD; Sieber, T | 1 |
| Costello, D; Gratch, D; Heropoulos, M; Kim, JY; McNulty, SE | 1 |
| Fowler, SB; Hertzog, J; Wagner, BK | 1 |
| Tobias, JD | 1 |
| Ujhelyi, MR | 1 |
| Moore, M; Newman, JP; Terris, DJ | 1 |
| Roelofse, JA; van der Bijl, P | 1 |
| Bailine, SH; Bernstein, S; Safferman, A; Vital-Herne, J | 1 |
| Gratch, D; Kim, JY; McNulty, SE | 1 |
| Deshpande, JK; Gregory, DF; Tobias, JD | 1 |
| Hall, JB; Pohlman, AS; Simpson, KP | 1 |
| Bredahl, C; Grevy, C; Jensen, S; Kirkegaard, L; Knudsen, L; Mandøe, H; Stjernholm, PH | 1 |
| McLachlan, RS; Sharpe, MD; Sprenger, H | 1 |
| Lee, KR; Rajanna, K | 1 |
| Finder, RL; Moore, PA | 1 |
| Hadbavny, AM; Hoyt, JW | 1 |
| Mooren, RA; Swart, EL; van Loenen, AC | 1 |
| Boysen, PG; Cernaianu, AC; Cilley, JH; DelRossi, AJ; Flum, DR; Grosso, MA; Ross, SE; Vassilidze, TV | 1 |
| Mitchell, WG | 1 |
| Berde, C; Billet, C; Kost-Byerly, S; Yaster, M | 1 |
| Allen, LV; Prince, SJ; Stiles, ML | 1 |
| Gunawan, S; Jiang, Q; Treiman, DM; Walton, NY | 1 |
| Damron, DS; Hong, SJ; Murray, PA | 1 |
| Cash, J; Chester, EA; Grant, MJ; Lugo, RA; Vernon, DD | 1 |
| Larson, JS; Lunn, JJ | 1 |
| Bleck, TP | 1 |
| Swart, EL; Thijs, LG; van Loenen, AC; van Schijndel, RJ | 1 |
| Byrne, TK; McCollam, JS; Norcross, ED; O'Neil, MG; Reeves, ST | 1 |
| Burke, MD; Firmin, RK; Killer, H; Lawson, G; Mulla, H; Upton, DU; von Anrep, C | 1 |
| Coté, J; McPherson, C; Peters, K; Tyebkhan, J | 1 |
| Hilton, A; Knudsen, N; Reves, JG; Young, C | 1 |
| Geffen, J | 1 |
| Bailey, JM | 1 |
| Barr, J; Bertaccini, EJ; Geller, E; Shafer, SL; Zomorodi, K | 1 |
| Cheng, DC; Dowd, NP; Fiducia, D; Gajula, S; Karski, JM; Munro, JA; Seneviratne, P | 1 |
| Buczko, GB | 1 |
| Prielipp, RC; Young, CC | 1 |
| Agelink, MW; Andrich, J; Majewski, TB; Mueck-Weymann, M | 1 |
| Deem, S | 1 |
| Izurieta, R; Rabatin, JT | 1 |
| Feck, AS; Goodchild, JH; Silverman, MD | 1 |
| Agrawal, D; Gupta, R; Krauss, B; Manzi, SF | 1 |
| Danhof, M; de Jongh, J; Strack van Schijndel, RM; Swart, EL; Thijs, LG; Zuideveld, KP | 2 |
| Price, SR | 1 |
| Caruso, LJ; Larsen, B; Villariet, DB | 1 |
| Dresden, GM; Levitt, MA; Nobay, F; Simon, BC | 1 |
| Gerritse, BE; Mitchell, AR; Spurrell, PA; Sulke, N | 1 |
| Marik, PE; Varon, J | 1 |
| Alexander, J; Allen, MH; Huf, G | 1 |
| Danhof, M; de Jongh, J; Strack van Schijndel, RJ; Swart, EL; Thijs, LG; Zuideveld, KP | 1 |
| Astori, M; Cigada, M; Di Mauro, P; Iapichino, G; Marzorati, S; Noto, A; Pezzi, A; Valdambrini, F; Zaniboni, M | 1 |
| Walker, M | 1 |
| MacLaren, R; Sullivan, PW | 1 |
| Al-Roomi, K; Krishnan, PR; Prasad, K; Sequeira, R | 2 |
| Malmgren, K | 1 |
| Dasta, JF; Jacobi, J; McLaughlin, TP; Sesti, AM | 1 |
| Anserimo, M; Forster, BB; Lennox, P; Mayson, K | 1 |
| Allen, RH; Fitzmaurice, G; Goldberg, AB; Kumar, D; Lifford, KL | 1 |
| Cearnal, L | 1 |
| France, CP; Javors, MA; McMahon, LR | 1 |
| Cassaro, S; DeCarolis, DD; Ho, L; Rice, KL; Willenbring, ML | 1 |
| Homann, N; Ludwig, D; Sauer, A; von Jagow, DC; Weitz, G; Wellhöner, P | 1 |
| Ahonen, J; Olkkola, KT | 1 |
| Bonomo, JB; Butler, AS; Lindsell, CJ; Venkat, A | 1 |
| Boohene, J; Bruera, E; Calderon, B; Curry Iii, E; Elsayem, A; Hung, F; Munsell, MF | 1 |
| Kalita, J; Misra, UK; Nair, PP | 1 |
| Mandrioli, R; Mercolini, L; Raggi, MA | 1 |
| Millikan, D; Rice, B; Silbergleit, R | 1 |
| Wheless, JW | 1 |
| Darbra, S; Pallarès, M | 1 |
| Alexander, J; Allen, MH; Huf, G; Raveendran, NS | 1 |
| Forster, BB; Keogh, C; Lennox, P; Mayson, K; Middelkamp, JE | 1 |
| Adams, CE; Coutinho, ES; Huf, G | 1 |
| Short, J | 1 |
| Hanling, S; Mecklenburg, B; Wallace, S | 1 |
| Gunn, J; Kriger, S; Terrell, AR | 1 |
| Anderson, M | 1 |
| Birrer, KL; Cheatham, ML; Dasta, JF; Gesin, G; Kane-Gill, SL; Kolnik, LJ | 1 |
| Aloysi, AS; Kellner, CH; Popeo, DM | 1 |
| Lagae, L | 1 |
| Frontera, JA | 1 |
| Choi, H; Chung, H; Chung, KH; Han, E; In, S; Lee, S | 1 |
| Gathwala, G; Goel, M; Mittal, K; Singh, J | 1 |
| Lubnin, AIu; Savin, IA; Sokolova, EIu | 1 |
| Conwit, R; Durkalski, V; Lowenstein, D; Silbergleit, R | 1 |
| Barnard, JP; Chan, BO; Kibblewhite, DP; Lala, HM; Lala, MP | 1 |
| da Silva, PS; Passos, RM; Waisberg, DR | 1 |
| Bak, M; Marcelis, M; van Os, J | 1 |
| Jagsch, C; Kierner, KA; Watzke, HH | 1 |
| Barsan, W; Conwit, R; Durkalski, V; Lowenstein, D; Palesch, Y; Pancioli, A; Silbergleit, R | 1 |
| Hirsch, LJ | 1 |
| Aneja, S | 1 |
| Cheng, Y; Liao, X; Xue, FS | 1 |
| Asmussen, S; Maybauer, DM; Maybauer, MO | 1 |
| Alldredge, B; Bell, R; Bleck, TP; Brophy, GM; Claassen, J; Glauser, T; LaRoche, SM; Riviello, JJ; Shutter, L; Sperling, MR; Treiman, DM; Vespa, PM | 1 |
| Akingbola, OA; Singh, D | 1 |
| Anania, S; Andrighi, E; Barello, S; Cadringher, P; Cerri, B; Corbella, D; Di Carlo, A; Formenti, P; Iapichino, G; Mantovani, ES; Martinetti, F; Mistraletti, G; Spanu, P; Umbrello, M | 1 |
| Ceschi, A; Fuchs, J; Mordasini, R; Nentwig, W; von Dechend, M | 1 |
| Barton, RG; Kimball, EJ; Lonardo, NW; Ludwig, K; Mone, MC; Nechodom, K; Nirula, R; Sauer, BC; Teng, C; Zhou, X | 1 |
| Brown, CV; Crispo, AL; Daley, MJ; Harford, PH; Pepin, JL | 1 |
| Al-Roomi, K; Krishnan, PR; Prasad, M; Sequeira, R | 1 |
| Conwit, R; Durkalski-Mauldin, VL; Lewandowski, C; Lowenstein, DH; Mahajan, PV; Nicholas, K; Silbergleit, R; Welch, RD | 1 |
| Kim, MH; Lee, SH; Park, BJ; Park, SG; Shin, JY; Shin, SM | 1 |
| Kim, MH; Park, BJ; Park, HJ; Shin, JY | 1 |
| Burke, JF; Durkalski, V; Meurer, WJ; Nicholas, KS; Silbergleit, R | 1 |
| Fu, R; Goldstein, JN | 1 |
| Alanis, LR; Bettega, PV; da Silva, S; de Lima, AA; do Prado, AM; Gregio, AM; Ignacio, SA; Johann, AC; Rinaldi, M; Rocha, F; Rosa, EA; Sari, Y | 1 |
| Cai, Y; Chen, K; Chen, Y; Lu, Z; Pan, SM; Xin, YC | 1 |
| Kälviäinen, R | 1 |
| Alvarez, V; Drislane, FW; Dworetzky, BA; Lee, JW; Novy, J; Rossetti, AO; Westover, MB | 1 |
| Diviney, M; Henshall, DC; Reynolds, JP | 1 |
| Burns, K; Burry, L; Cook, D; Devlin, JW; Dodek, P; Ferguson, N; Fergusson, D; Fowler, RA; Granton, J; Jacka, M; Keenan, S; Luk, E; Mallick, R; Mehta, S; Olafson, K; Reynolds, S; Rose, L; Skrobik, Y; Steinberg, M; Tanios, M | 1 |
| Kellinghaus, C; Lang, N; Rosenow, F; Rossetti, AO; Rüegg, S; Tilz, C; Trinka, E; Unterberger, I; Uzelac, Z | 1 |
| Adjepong, YA; Lukens, C; Manthous, CA; Musial, B; Perez, R; Stewart, R | 1 |
| Fan, JC; Feng, K; Wang, HY; Wen, B; Yang, ZB; Zhao, ZY | 1 |
| Cameron, R | 1 |
| Alexander, J; Allen, MH; Gandhi, P; Huf, G | 1 |
| Benowitz, NL; Horng, H; Smollin, CG; Vo, KT | 1 |
| Brunkhorst, J; Carter, BS | 1 |
| Duncan-Azadi, CR; Gormley, A; Johnson, PN | 1 |
| Bailey, AM; Baum, RA; Horn, K; Justice, SN; Lewis, T; Morizio, K; Schultz, A; Weant, K | 1 |
| Kousgaard, SJ; Licht, RW; Nielsen, RE | 1 |
| Appleton, R; Martland, T; McTague, A | 1 |
| Collier, HK; Himebauch, AS; Warrington, SE; Wolfe, HA | 1 |
| Joynt, GM; Lee, A; Ling, L; Tse, AHW | 1 |
| Bak, E; Bak, M; Bervoets, C; Bienkowski, P; De Fruyt, J; Dom, G; Drukker, M; Fiorillo, A; Frydecka, D; Misiak, B; Preuss, WU; Samochowiec, A; Samochowiec, J; Sampogna, G; Weltens, I | 1 |
| Betjemann, JP; Guterman, EL; Josephson, SA; Lowenstein, DH | 1 |
| Chung, JY; Hatley, O; Kim, Y; Lee, H; Lee, HA; Rhee, SJ; Yi, S; Yoon, S; Yu, KS | 1 |
| Bautista, C; Cotugno, S; Deng, Y; Dhakar, MB; Farooque, P; Hirsch, LJ; Maciel, CB; McKimmy, D; Owusu, KA; Sukumar, N | 1 |
| Balevic, S; Chu, V; Clark, R; Crenshaw, EG; Dallefeld, SH; Daniel, KR; Gilleskie, ML; Greenberg, RG; Kumar, KR; Smith, DS; Smith, PB; Zimmerman, KO | 1 |
| Chuck, CC; Claassen, J; Han, EJ; Madsen, TE; Martin, TJ; Reznik, ME | 1 |
| Bleck, TP; Chamberlain, JM; Cloyd, JC; Cock, HR; Coles, LD; Conwit, RA; Elm, JJ; Fountain, NB; Kapur, J; Lowenstein, DH; Rosenthal, ES; Sathe, AG; Shinnar, S; Silbergleit, R; Underwood, E | 1 |
| Burke, JF; Guterman, EL; Sporer, KA | 1 |
| Conrardy, MJ; Cruz, DS; Fant, AL; Kim, HS; Lank, PM; Malik, S; Tyler, DJ | 1 |
| Foudraine, N; Janssen, PKC; le Noble, JLML; Shudofsky, KN | 1 |
| Aucott, L; Booth, C; Brazzelli, M; Counsell, C; Cruickshank, M; Imamura, M; Manson, P; Scotland, G | 1 |
| Huecker, M; Javed, J; Roy, D; Senn, J; Shaw, I; Shreffler, J; Thiemann, P; Thomas, A | 1 |
| Bhatty, S; Hasan, SU; Naeem, A; Naseeb, MW; Pervez, A; Shamim, S | 1 |
| Chaitra, R; Jain, V; Konanki, R; Sharma, R; Srivastava, K | 1 |
| Beuchat, I; Gelhard, S; Kay, L; Kienitz, R; Lucaciu, A; Mann, C; Rosenow, F; Schäfer, JH; Schubert-Bast, S; Siebenbrodt, K; Strzelczyk, A; von Brauchitsch, S; Willems, LM; Zöllner, JP | 1 |
| Bengelink, EM; Durkalski, V; Sherman, NA; Silbergleit, R; Wolter, KD | 1 |
| Gidal, BE; Kotloski, RJ | 1 |
| Allen, PJ; Johanson, KE; Lock, AE; Neff, LA; Reveles, KR | 1 |
| Adams, KS; Cassel, JB; Fatima, Z; Hartung, N; Noreika, DM | 1 |
47 review(s) available for lorazepam and midazolam
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Oral benzodiazepines and conscious sedation: a review.
Topics: Administration, Oral; Alprazolam; Ambulatory Surgical Procedures; Anti-Anxiety Agents; Conscious Sedation; Diazepam; Flurazepam; Humans; Lorazepam; Midazolam; Oxazepam; Premedication; Receptors, GABA-A; Temazepam; Triazolam | 1992 |
Rebound insomnia and elimination half-life: assessment of individual subject response.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Flurazepam; Half-Life; Humans; Lorazepam; Midazolam; Middle Aged; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Time Factors; Triazolam | 1985 |
[Current intravenous anesthetics].
Topics: Anesthesia, Intravenous; Anesthetics; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Etomidate; Flunitrazepam; Imidazoles; Injections, Intravenous; Lorazepam; Medazepam; Midazolam; Nordazepam | 1980 |
Modern trends in the investigation of new hypnotics in anaesthesia.
Topics: Anesthesia; Anti-Anxiety Agents; Arousal; Benzodiazepines; Electroencephalography; Electrophysiology; Flunitrazepam; Half-Life; Humans; Hypnotics and Sedatives; Lorazepam; Midazolam; Psychometrics | 1984 |
Pharmacological interventions for agitation in head-injured patients in the acute care setting.
Topics: Adult; Brain Injuries; Critical Care; Dose-Response Relationship, Drug; Drug Administration Schedule; Haloperidol; Humans; Lorazepam; Male; Midazolam; Multiple Trauma; Neurologic Examination; Nursing Assessment; Propofol; Psychomotor Agitation | 1995 |
Benzodiazepines for intravenous conscious sedation: agonists and antagonists.
Topics: Anesthesia, Dental; Benzodiazepines; Conscious Sedation; Diazepam; Flumazenil; Humans; Injections, Intravenous; Lorazepam; Midazolam | 1993 |
Status epilepticus and acute repetitive seizures in children, adolescents, and young adults: etiology, outcome, and treatment.
Topics: Adolescent; Adult; Age Factors; Aged; Anticonvulsants; Benzodiazepines; Central Nervous System Diseases; Child; Diazepam; Epilepsia Partialis Continua; Epilepsy; Humans; Lorazepam; Midazolam; Middle Aged; Pentobarbital; Phenytoin; Recurrence; Seizures; Status Epilepticus; Treatment Outcome | 1996 |
The management of opioid and benzodiazepine dependence in infants, children, and adolescents.
Topics: Adolescent; Analgesia, Patient-Controlled; Anti-Anxiety Agents; Child; Child, Preschool; Drug Administration Schedule; Female; Humans; Infant; Infant, Newborn; Lorazepam; Male; Midazolam; Morphine; Morphine Dependence; Substance-Related Disorders | 1996 |
Comparing drugs for short-term sedation.
Topics: Anesthesia; Benzodiazepines; Conscious Sedation; Diazepam; Flumazenil; Humans; Lorazepam; Midazolam; Pain; Propofol | 1994 |
Management approaches to prolonged seizures and status epilepticus.
Topics: Anticonvulsants; Benzodiazepines; Diazepam; Drug Administration Schedule; Drug Therapy, Combination; Humans; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Propofol; Seizures; Status Epilepticus; Treatment Outcome | 1999 |
Sedation in the intensive care unit.
Topics: Decision Making; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Midazolam; Propofol | 2000 |
Sedation in critically ill patients: a review.
Topics: Adult; Age Factors; Aged; Analgesics; Critical Illness; Electroencephalography; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Midazolam; Monitoring, Physiologic; Obesity; Propofol; Risk Factors; Time Factors | 2001 |
Benzodiazepines in the intensive care unit.
Topics: Anti-Anxiety Agents; Critical Care; Diazepam; Half-Life; Humans; Intensive Care Units; Lorazepam; Midazolam | 2001 |
Sedation during mechanical ventilation: a systematic review.
Topics: Adult; Anesthetics; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Midazolam; Propofol; Respiration, Artificial; Respiratory Insufficiency | 2002 |
The management of status epilepticus.
Topics: Anticonvulsants; Humans; Lorazepam; Midazolam; Propofol; Status Epilepticus | 2004 |
Haloperidol plus promethazine for psychosis induced aggression.
Topics: Aggression; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; Promethazine; Psychomotor Agitation; Psychotic Disorders; Randomized Controlled Trials as Topic | 2005 |
Status epilepticus: an evidence based guide.
Topics: Anticonvulsants; Chronic Disease; Critical Care; Drug Administration Routes; Emergency Treatment; Evidence-Based Medicine; Humans; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Prognosis; Randomized Controlled Trials as Topic; Referral and Consultation; Status Epilepticus | 2005 |
Anticonvulsant therapy for status epilepticus.
Topics: Anticonvulsants; Diazepam; Humans; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus | 2005 |
Anticonvulsant therapy for status epilepticus.
Topics: Anticonvulsants; Diazepam; Humans; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus | 2007 |
Midazolam and other benzodiazepines.
Topics: Anesthetics, Intravenous; Animals; Benzodiazepines; Biotransformation; Central Nervous System; Diazepam; Dose-Response Relationship, Drug; Drug Interactions; Flumazenil; Humans; Lorazepam; Midazolam; Molecular Structure; Receptors, GABA-A; Structure-Activity Relationship | 2008 |
Benzodiazepine metabolism: an analytical perspective.
Topics: Alprazolam; Animals; Anti-Anxiety Agents; Azepines; Benzodiazepines; Bromazepam; Chromatography, High Pressure Liquid; Diazepam; Humans; Lorazepam; Mass Spectrometry; Midazolam; Triazolam | 2008 |
Emergency treatment of status epilepticus: current thinking.
Topics: Anesthesia, General; Anticonvulsants; Benzodiazepines; Electroencephalography; Emergency Medical Services; Emergency Service, Hospital; Humans; Lorazepam; Midazolam; Phenytoin; Status Epilepticus | 2009 |
Treatment of status epilepticus in children.
Topics: Anticonvulsants; Child; Child, Preschool; Diazepam; Drug Administration Schedule; Drug Therapy, Combination; Emergency Medical Services; Hospitalization; Humans; Lorazepam; Midazolam; Pediatrics; Phenytoin; Practice Guidelines as Topic; Recurrence; Status Epilepticus; Treatment Outcome | 2004 |
Haloperidol plus promethazine for psychosis-induced aggression.
Topics: Aggression; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; Olanzapine; Promethazine; Psychomotor Agitation; Psychotic Disorders; Randomized Controlled Trials as Topic | 2009 |
[Haloperidol plus promethazine for agitated patients--a systematic review].
Topics: Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; Olanzapine; Promethazine; Psychomotor Agitation; Randomized Controlled Trials as Topic | 2009 |
Benzodiazepines for prolonged seizures.
Topics: Anticonvulsants; Benzodiazepines; Child, Preschool; Diazepam; Humans; Infant; Lorazepam; Midazolam; Status Epilepticus | 2010 |
Clinical practice: the treatment of acute convulsive seizures in children.
Topics: Acute Disease; Anticonvulsants; Benzodiazepines; Child; Diazepam; GABA Modulators; Humans; Lorazepam; Midazolam; Seizures | 2011 |
Delirium and sedation in the ICU.
Topics: Conscious Sedation; Delirium; Dexmedetomidine; Diagnosis, Differential; Hospital Mortality; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Midazolam; Neurologic Examination; Prognosis; Risk Factors; Survival Rate | 2011 |
[Non-convulsive epileptic status].
Topics: Anticonvulsants; Diagnosis, Differential; Electroencephalography; Humans; Lorazepam; Midazolam; Status Epilepticus | 2011 |
[Rapid tranquillisation; review of the literature and recommendations].
Topics: Aggression; Benzodiazepines; Conscious Sedation; Drug Therapy, Combination; Haloperidol; Humans; Hypnotics and Sedatives; Lorazepam; Midazolam; Olanzapine; Practice Guidelines as Topic; Promethazine; Psychotic Disorders; Time Factors; Treatment Outcome | 2011 |
A verified spider bite and a review of the literature confirm Indian ornamental tree spiders (Poecilotheria species) as underestimated theraphosids of medical importance.
Topics: Animals; Creatine Kinase; Humans; Lorazepam; Magnesium; Male; Midazolam; Middle Aged; Muscle Cramp; Pets; Spider Bites; Spider Venoms; Spiders; Switzerland; Treatment Outcome | 2014 |
Anticonvulsant therapy for status epilepticus.
Topics: Anticonvulsants; Diazepam; Humans; Injections, Intravenous; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Randomized Controlled Trials as Topic; Status Epilepticus | 2014 |
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients.
Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Bradycardia; Clonidine; Conscious Sedation; Critical Illness; Dexmedetomidine; Humans; Lorazepam; Midazolam; Propofol; Randomized Controlled Trials as Topic; Respiration, Artificial; Selection Bias; Time Factors | 2015 |
Intranasal therapies for acute seizures.
Topics: Acute Disease; Administration, Intranasal; Anticonvulsants; Diazepam; Humans; Lorazepam; Midazolam; Seizures | 2015 |
A Comparison of Midazolam, Lorazepam, and Diazepam for the Treatment of Status Epilepticus in Children: A Network Meta-analysis.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Diazepam; Humans; Infant; Lorazepam; Midazolam; Network Meta-Analysis; Status Epilepticus; Young Adult | 2016 |
Haloperidol plus promethazine for psychosis-induced aggression.
Topics: Aggression; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Lorazepam; Midazolam; Promethazine; Psychomotor Agitation; Psychotic Disorders; Randomized Controlled Trials as Topic; Restraint, Physical | 2016 |
Neonatal pain management.
Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Barbiturates; Chronic Pain; Cyclohexanecarboxylic Acids; Dexmedetomidine; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Neonatal; Kangaroo-Mother Care Method; Ketamine; Lorazepam; Midazolam; Neonatal Abstinence Syndrome; Pain Management; Pain Measurement; Palliative Care; Propofol; Sucking Behavior; Sucrose; Terminal Care | 2017 |
Review of Intranasally Administered Medications for Use in the Emergency Department.
Topics: Administration, Intranasal; Anesthetics, Dissociative; Anticonvulsants; Antidotes; Antipsychotic Agents; Dexmedetomidine; Emergency Service, Hospital; Fentanyl; Flumazenil; Haloperidol; Humans; Hydromorphone; Hypnotics and Sedatives; Ketamine; Lorazepam; Midazolam; Naloxone; Narcotic Antagonists; Narcotics | 2017 |
Effects of Intramuscular Midazolam and Lorazepam on Acute Agitation in Non-Elderly Subjects - A Systematic Review.
Topics: Anti-Anxiety Agents; Humans; Injections, Intramuscular; Lorazepam; Midazolam; Psychomotor Agitation | 2017 |
Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children.
Topics: Administration, Inhalation; Administration, Oral; Administration, Rectal; Anticonvulsants; Child; Diazepam; Epilepsy, Tonic-Clonic; Humans; Injections, Intramuscular; Injections, Intravenous; Lorazepam; Midazolam; Randomized Controlled Trials as Topic; Status Epilepticus | 2018 |
Altered Pharmacokinetics in Prolonged Infusions of Sedatives and Analgesics Among Adult Critically Ill Patients: A Systematic Review.
Topics: Adult; Analgesics; Critical Illness; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lorazepam; Midazolam; Morphine; Propofol; Remifentanil; Sufentanil; Time Factors | 2018 |
The pharmacological management of agitated and aggressive behaviour: A systematic review and meta-analysis.
Topics: Aggression; Anti-Anxiety Agents; Antipsychotic Agents; Benzodiazepines; Drug Therapy, Combination; Haloperidol; Humans; Hypnotics and Sedatives; Lorazepam; Midazolam; Olanzapine; Promethazine; Psychomotor Agitation; Psychotic Disorders; Treatment Outcome | 2019 |
Management of the first stage of convulsive status epilepticus in adults: a systematic review of current randomised evidence.
Topics: Adult; Anticonvulsants; Diazepam; Humans; Lorazepam; Midazolam; Seizures; Status Epilepticus | 2022 |
Termination of seizures in the paediatric age group, best benzodiazepine and route of administration: A network meta-analysis.
Topics: Anticonvulsants; Benzodiazepines; Child; Diazepam; Humans; Lorazepam; Midazolam; Network Meta-Analysis; Seizures; Status Epilepticus | 2022 |
Benzodiazepines in the Management of Seizures and Status Epilepticus: A Review of Routes of Delivery, Pharmacokinetics, Efficacy, and Tolerability.
Topics: Anticonvulsants; Benzodiazepines; Clonazepam; Diazepam; gamma-Aminobutyric Acid; Humans; Lorazepam; Midazolam; Seizures; Status Epilepticus | 2022 |
Rescue Treatments for Seizure Clusters.
Topics: Adolescent; Adult; Anticonvulsants; Benzodiazepines; Diazepam; Humans; Lorazepam; Midazolam; Nasal Sprays; Seizures; Status Epilepticus | 2022 |
34 trial(s) available for lorazepam and midazolam
| Article | Year |
|---|---|
[Beta activation following the intravenous administration of benzodiazepines and the specific antagonist flumazenil (Ro 15-1788)].
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Beta Rhythm; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Flumazenil; Flunitrazepam; Humans; Injections, Intravenous; Lorazepam; Male; Midazolam; Prospective Studies; Randomized Controlled Trials as Topic; Stimulation, Chemical | 1990 |
Comparison of various physiologic and psychomotor parameters in patients sedated with intravenous lorazepam, diazepam, or midazolam during oral surgery.
Topics: Adolescent; Adult; Analysis of Variance; Anesthesia, Dental; Anesthesia, Local; Anxiety; Blood Pressure; Conscious Sedation; Diazepam; Female; Heart Rate; Humans; Lorazepam; Male; Midazolam; Molar, Third; Respiration; Surgery, Oral; Tooth Extraction | 1991 |
Effects of hypnotics on sleep and psychomotor performance. A double-blind randomised study of lormetazepam, midazolam and zopiclone.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Midazolam; Middle Aged; Piperazines; Psychomotor Performance; Sleep; Time Factors | 1990 |
Rebound insomnia and elimination half-life: assessment of individual subject response.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Flurazepam; Half-Life; Humans; Lorazepam; Midazolam; Middle Aged; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Time Factors; Triazolam | 1985 |
Midazolam vs lorazepam and placebo as hypnotic premedication before surgery. A controlled, double-blind study.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lorazepam; Male; Midazolam; Middle Aged; Preanesthetic Medication; Random Allocation; Sleep | 1985 |
The effectiveness of oral midazolam as a hypnotic compared with lorazepam.
Topics: Administration, Oral; Adolescent; Adult; Aged; Benzodiazepines; Double-Blind Method; Drug Evaluation; Female; Half-Life; Humans; Lorazepam; Male; Midazolam; Middle Aged; Random Allocation; Sleep; Sleep Initiation and Maintenance Disorders | 1986 |
Saccadic eye movements in determination of the residual effects of the benzodiazepines.
Topics: Benzodiazepines; Eye Movements; Flunitrazepam; Humans; Hypnotics and Sedatives; Lorazepam; Midazolam; Placebos; Saccades; Sleep; Time Factors | 1986 |
Left ventricular regional wall motion and haemodynamic changes following bolus administration of pipecuronium or pancuronium to adult patients undergoing coronary artery bypass grafting.
Topics: Adult; Aged; Anesthetics, Intravenous; Blood Pressure; Cardiac Output; Central Venous Pressure; Coronary Artery Bypass; Echocardiography, Transesophageal; Electrocardiography; Female; Heart Rate; Humans; Hypnotics and Sedatives; Lorazepam; Male; Midazolam; Middle Aged; Myocardial Ischemia; Neuromuscular Nondepolarizing Agents; Pancuronium; Pipecuronium; Sufentanil; Thoracotomy; Vecuronium Bromide; Ventricular Function, Left | 1995 |
The effect of midazolam and lorazepam on postoperative recovery after cardiac surgery.
Topics: Age Factors; Aged; Anesthesia Recovery Period; Awareness; Coronary Artery Bypass; Female; Humans; Intraoperative Care; Intubation, Intratracheal; Lorazepam; Male; Midazolam; Middle Aged; Morphine; Pain, Postoperative; Placebos; Single-Blind Method; Stroke Volume; Ventricular Dysfunction | 1995 |
Cardiac dysrhythmias associated with intravenous lorazepam, diazepam, and midazolam during oral surgery.
Topics: Adolescent; Adult; Analysis of Variance; Anesthesia, Dental; Anti-Anxiety Agents; Arrhythmias, Cardiac; Conscious Sedation; Diazepam; Female; Humans; Lorazepam; Male; Midazolam; Molar, Third; Tooth Extraction | 1994 |
Comparative vascular effects of midazolam and lorazepam administered during cardiopulmonary bypass.
Topics: Aged; Analysis of Variance; Anesthesia; Cardiopulmonary Bypass; Coronary Artery Bypass; Female; Fentanyl; Heart Valve Prosthesis; Hemodynamics; Humans; Lorazepam; Male; Midazolam; Middle Aged; Vascular Resistance | 1994 |
Continuous intravenous infusions of lorazepam versus midazolam for sedation during mechanical ventilatory support: a prospective, randomized study.
Topics: Adult; Clinical Protocols; Conscious Sedation; Critical Care; Female; Fluid Therapy; Humans; Infusions, Intravenous; Injections, Intravenous; Lorazepam; Male; Midazolam; Middle Aged; Prospective Studies; Psychomotor Agitation; Respiration, Artificial; Severity of Illness Index; Survival Rate; Time Factors; Wakefulness | 1994 |
[Midazolam and lorazepam as premedication. A randomized double-blind study].
Topics: Administration, Oral; Adult; Aged; Double-Blind Method; Female; Genital Diseases, Female; Hip Prosthesis; Humans; Lorazepam; Midazolam; Middle Aged; Patient Satisfaction; Preanesthetic Medication | 1994 |
Lorazepam and midazolam in the intensive care unit: a randomized, prospective, multicenter study of hemodynamics, oxygen transport, efficacy, and cost.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Cost-Benefit Analysis; Critical Illness; Drug Costs; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Male; Midazolam; Middle Aged; Oxygen Consumption; Prospective Studies; Respiration, Artificial | 1996 |
Continuous infusion of lorazepam versus medazolam in patients in the intensive care unit: sedation with lorazepam is easier to manage and is more cost-effective.
Topics: Adult; Aged; Conscious Sedation; Cost Savings; Cost-Benefit Analysis; Critical Care; Double-Blind Method; Drug Costs; Drug Monitoring; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lorazepam; Male; Midazolam; Middle Aged; Neurologic Examination; Respiration, Artificial; Therapeutic Equivalency; Time Factors | 1999 |
Continuous infusions of lorazepam, midazolam, and propofol for sedation of the critically ill surgery trauma patient: a prospective, randomized comparison.
Topics: Adolescent; Adult; Aged; Conscious Sedation; Costs and Cost Analysis; Critical Illness; Drug Costs; Female; Follow-Up Studies; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Lorazepam; Male; Midazolam; Middle Aged; Propofol; Prospective Studies; Respiration, Artificial; Safety; Treatment Outcome; Wounds and Injuries | 1999 |
A double-blind, randomized comparison of i.v. lorazepam versus midazolam for sedation of ICU patients via a pharmacologic model.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Amnesia; Double-Blind Method; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Male; Midazolam; Middle Aged; Models, Biological; Prospective Studies | 2001 |
Fast-track cardiac anaesthesia in the elderly: effect of two different anaesthetic techniques on mental recovery.
Topics: Aged; Anesthesia, General; Anesthetics, Intravenous; Anti-Anxiety Agents; Cognition Disorders; Consciousness; Coronary Artery Bypass; Female; Hemodynamics; Humans; Length of Stay; Lorazepam; Male; Midazolam; Postoperative Complications; Propofol; Prospective Studies; Psychometrics | 2001 |
Short-term effects of intravenous benzodiazepines on autonomic neurocardiac regulation in humans: a comparison between midazolam, diazepam, and lorazepam.
Topics: Adult; Autonomic Nervous System; Benzodiazepines; Diazepam; Female; Flumazenil; Heart; Heart Rate; Humans; Injections, Intravenous; Lorazepam; Male; Midazolam; Middle Aged; Preanesthetic Medication; Prospective Studies | 2002 |
Comparative population pharmacokinetics of lorazepam and midazolam during long-term continuous infusion in critically ill patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Critical Illness; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lorazepam; Male; Midazolam; Middle Aged; Plasma; Positive-Pressure Respiration | 2004 |
A prospective, double-blind, randomized trial of midazolam versus haloperidol versus lorazepam in the chemical restraint of violent and severely agitated patients.
Topics: Adult; Arousal; Blood Pressure; Double-Blind Method; Haloperidol; Heart Rate; Humans; Lorazepam; Midazolam; Prospective Studies; Psychomotor Agitation; Respiratory Mechanics; Tranquilizing Agents; Treatment Outcome; Violence | 2004 |
Improving the acceptability of the atrial defibrillator for the treatment of persistent atrial fibrillation: the atrial defibrillator sedation assessment study (ADSAS).
Topics: Adult; Aged; Aged, 80 and over; Analgesics; Atrial Fibrillation; Chronic Disease; Confidence Intervals; Conscious Sedation; Cross-Over Studies; Cyclizine; Defibrillators, Implantable; Dextromoramide; Drug Therapy, Combination; Female; Humans; Lorazepam; Male; Midazolam; Middle Aged; Morphine; Pain Measurement; Patient Acceptance of Health Care; Premedication; Probability; Reference Values; Risk Assessment; Single-Blind Method; Treatment Outcome | 2004 |
Sedation in the critically ill ventilated patient: possible role of enteral drugs.
Topics: Administration, Oral; Analgesics, Opioid; Conscious Sedation; Critical Care; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Therapy, Combination; Female; Fentanyl; Humans; Hydroxyzine; Hypnotics and Sedatives; Infusions, Intravenous; Lorazepam; Male; Midazolam; Propofol; Respiration, Artificial; Treatment Outcome | 2005 |
Population pharmacodynamic modelling of lorazepam- and midazolam-induced sedation upon long-term continuous infusion in critically ill patients.
Topics: Adult; Aged; Aged, 80 and over; Algorithms; Chromatography, High Pressure Liquid; Conscious Sedation; Critical Illness; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Inpatients; Intensive Care Units; Lorazepam; Male; Midazolam; Middle Aged; Models, Biological; Respiration, Artificial | 2006 |
Premedication with orally administered lorazepam in adults undergoing ERCP: a randomized double-blind study.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Cholangiopancreatography, Endoscopic Retrograde; Conscious Sedation; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lorazepam; Male; Midazolam; Middle Aged; Preanesthetic Medication; Propofol; Psychomotor Agitation | 2007 |
Use of dexmedetomidine for primary sedation in a general intensive care unit.
Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Clinical Nursing Research; Clinical Protocols; Conscious Sedation; Critical Care; Dexmedetomidine; Drug Monitoring; Drug Utilization; Humans; Hypnotics and Sedatives; Kansas; Length of Stay; Lorazepam; Midazolam; Nursing Assessment; Propofol; Respiration, Artificial; Safety; Treatment Outcome | 2010 |
Intravenous diazepam, midazolam and lorazepam in acute seizure control.
Topics: Acute Disease; Adolescent; Child; Child, Preschool; Diazepam; Female; Humans; Infant; Injections, Intravenous; Lorazepam; Male; Midazolam; Seizures; Treatment Outcome | 2012 |
RAMPART (Rapid Anticonvulsant Medication Prior to Arrival Trial): a double-blind randomized clinical trial of the efficacy of intramuscular midazolam versus intravenous lorazepam in the prehospital treatment of status epilepticus by paramedics.
Topics: Allied Health Personnel; Anticonvulsants; Emergency Medical Services; Humans; Injections, Intramuscular; Injections, Intraventricular; Lorazepam; Midazolam; Status Epilepticus; Treatment Outcome | 2011 |
Intramuscular versus intravenous therapy for prehospital status epilepticus.
Topics: Adolescent; Adult; Anticonvulsants; Child; Child, Preschool; Double-Blind Method; Emergency Medical Services; Female; Humans; Hypnotics and Sedatives; Infant; Infusions, Intravenous; Injections, Intramuscular; Lorazepam; Male; Midazolam; Middle Aged; Recurrence; Status Epilepticus; Time Factors; Treatment Outcome | 2012 |
Enteral vs. intravenous ICU sedation management: study protocol for a randomized controlled trial.
Topics: Administration, Oral; Anesthetics, Intravenous; Clinical Protocols; Computer-Assisted Instruction; Conscious Sedation; Consciousness; Critical Illness; Drug Therapy, Combination; Education, Medical, Continuing; Humans; Hydroxyzine; Hypnotics and Sedatives; Infusions, Intravenous; Inservice Training; Intensive Care Units; Internet; Italy; Lorazepam; Melatonin; Midazolam; Propofol; Research Design; Single-Blind Method; Treatment Outcome | 2013 |
Intramuscular midazolam versus intravenous lorazepam for the prehospital treatment of status epilepticus in the pediatric population.
Topics: Administration, Intravenous; Adolescent; Allied Health Personnel; Anticonvulsants; Child; Child, Preschool; Clinical Protocols; Female; Humans; Infant; Injections, Intramuscular; Lorazepam; Male; Midazolam; Status Epilepticus; Treatment Outcome; Young Adult | 2015 |
Accounting for repeat enrollments during an emergency clinical trial: the Rapid Anticonvulsant Medications Prior to Arrival Trial (RAMPART).
Topics: Adult; Aged; Allied Health Personnel; Anticonvulsants; Double-Blind Method; Female; Humans; Injections, Intramuscular; Injections, Intravenous; Lorazepam; Male; Midazolam; Middle Aged; Racial Groups; Research Design; Status Epilepticus | 2015 |
Prevalence, risk factors, and outcomes associated with physical restraint use in mechanically ventilated adults.
Topics: Adult; Aged; Alcohol Drinking; Analgesics, Opioid; Antipsychotic Agents; Benzodiazepines; Clinical Protocols; Device Removal; Female; Fentanyl; Haloperidol; Humans; Hydromorphone; Intensive Care Units; Lorazepam; Male; Midazolam; Middle Aged; Morphine; Multivariate Analysis; Prevalence; Proportional Hazards Models; Respiration, Artificial; Restraint, Physical; Risk Factors; Ventilators, Mechanical | 2016 |
Patterns of benzodiazepine underdosing in the Established Status Epilepticus Treatment Trial.
Topics: Adolescent; Adult; Age Factors; Benzodiazepines; Child; Diazepam; Dose-Response Relationship, Drug; Humans; Lorazepam; Midazolam; Status Epilepticus; Treatment Outcome; Young Adult | 2021 |
101 other study(ies) available for lorazepam and midazolam
| Article | Year |
|---|---|
Binding, partial agonism, and potentiation of alpha(1)-adrenergic receptor function by benzodiazepines: A potential site of allosteric modulation.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Benzodiazepines; Cell Membrane; Cells, Cultured; COS Cells; Drug Synergism; Epinephrine; Fibroblasts; Inositol Phosphates; Ligands; Molecular Conformation; Phenylephrine; Radioligand Assay; Rats; Receptors, Adrenergic, alpha-1; Signal Transduction; Transfection | 1999 |
Combining in vitro and in vivo pharmacokinetic data for prediction of hepatic drug clearance in humans by artificial neural networks and multivariate statistical techniques.
Topics: Animals; Biological Availability; Dogs; Humans; Least-Squares Analysis; Liver; Multivariate Analysis; Neural Networks, Computer; Pharmacokinetics; Rats | 1999 |
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Air to lung partition coefficients for volatile organic compounds and blood to lung partition coefficients for volatile organic compounds and drugs.
Topics: Air; Animals; Humans; Lung; Organic Chemicals; Probability; Rats; Tissue Distribution; Volatilization | 2008 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software | 2009 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate.
Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility | 2010 |
Effect of halothane anesthesia and trifluoroacetic acid on protein binding of benzodiazepines.
Topics: Adult; Anesthesia, Inhalation; Binding, Competitive; Diazepam; Drug Interactions; Halothane; Humans; Lorazepam; Midazolam; Middle Aged; Preanesthetic Medication; Protein Binding; Trifluoroacetic Acid | 1991 |
[Premedication and analgesic dose procedures in dental medicine].
Topics: Anesthesia, Dental; Anesthesia, Local; Buprenorphine; Clorazepate Dipotassium; Diazepam; Flunitrazepam; Humans; Lorazepam; Meperidine; Midazolam; Morphine; Oxazepam; Pain; Pentazocine; Pirinitramide; Preanesthetic Medication | 1991 |
[Antagonism of the effects of midazolam by flumazenil on the consumption of oxygen by the body].
Topics: Anesthesia; Flumazenil; Humans; Lorazepam; Midazolam; Oxygen Consumption; Postoperative Period; Preanesthetic Medication | 1989 |
Drug interactions and clinical pharmacokinetics of flumazenil.
Topics: Anti-Anxiety Agents; Benzodiazepines; Biological Availability; Drug Interactions; Ethanol; Flumazenil; Flunitrazepam; Half-Life; Humans; Liver; Lorazepam; Midazolam; Receptors, GABA-A; Tomography, Emission-Computed | 1988 |
Is midazolam a dangerous drug?
Topics: Anxiety; Diazepam; Humans; Lorazepam; Midazolam | 1989 |
Kinetics of diazepam, midazolam, and lorazepam in cigarette smokers.
Topics: Adult; Benzodiazepines; Diazepam; Female; Humans; Injections, Intravenous; Lorazepam; Male; Metabolic Clearance Rate; Midazolam; Nicotiana; Plants, Toxic; Smoking | 1985 |
A pharmacokinetic/pharmacodynamic/receptor binding model to predict the onset and duration of pharmacological activity of the benzodiazepines.
Topics: Animals; Anti-Anxiety Agents; Arousal; Benzodiazepines; Brain; Diazepam; Humans; Kinetics; Lorazepam; Metabolic Clearance Rate; Midazolam; Muridae; Receptors, Cell Surface; Receptors, GABA-A | 1983 |
Pharmacokinetics of benzodiazepines: metabolic pathways and plasma level profiles.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Bromazepam; Child; Clobazam; Flunitrazepam; Flurazepam; Humans; Hydroxylation; Kinetics; Lorazepam; Midazolam; Middle Aged; Nitrazepam; Nordazepam | 1984 |
Clinical effectiveness and untoward effects of new agents and techniques used in intravenous sedation.
Topics: Adult; Amnesia; Analgesics; Anesthesia, Dental; Anesthesia, Intravenous; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Female; Humans; Lorazepam; Male; Methohexital; Midazolam; Preanesthetic Medication | 1984 |
Diazepam-associated thrombophlebitis: a review and discussion of possible prevention.
Topics: Benzodiazepines; Diazepam; Humans; Injections, Intravenous; Lorazepam; Midazolam; Pharmaceutical Vehicles; Sodium Chloride; Thrombophlebitis; Veins | 1980 |
Benzodiazepines protect mice from local anesthetic convulsions and deaths.
Topics: Anesthetics; Animals; Benzodiazepines; Bupivacaine; Diazepam; Drug Interactions; Etidocaine; Female; Lidocaine; Lorazepam; Mice; Midazolam; Seizures | 1981 |
Continuous intravenous infusions of lorazepam versus midazolam for sedation.
Topics: Conscious Sedation; Drug Monitoring; Drug Stability; Humans; Infusions, Intravenous; Lorazepam; Midazolam | 1995 |
Lorazepam versus midazolam for sedation.
Topics: Adolescent; Adult; Child; Child, Preschool; Conscious Sedation; Critical Care; Drug Incompatibility; Humans; Infant; Infant, Newborn; Lorazepam; Midazolam | 1995 |
Lorazepam versus midazolam for sedation.
Topics: Conscious Sedation; Consciousness; Humans; Lorazepam; Midazolam; Statistics, Nonparametric | 1995 |
Trends in the management of alcohol withdrawal syndrome.
Topics: Adult; Aged; Aged, 80 and over; Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Chlordiazepoxide; Clinical Protocols; Diazepam; Drug Combinations; Ethanol; Female; Head and Neck Neoplasms; Humans; Lorazepam; Male; Midazolam; Middle Aged; Retrospective Studies; Substance Withdrawal Syndrome; Treatment Outcome | 1995 |
Flumazenil reversal of benzodiazepine-induced sedation for a patient with severe pre-ECT anxiety.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Electroconvulsive Therapy; Flumazenil; Humans; Lorazepam; Male; Midazolam; Schizophrenia | 1994 |
Outpatient therapy of iatrogenic drug dependency following prolonged sedation in the pediatric intensive care unit.
Topics: Child; Female; Fentanyl; Humans; Iatrogenic Disease; Infant; Lorazepam; Male; Methadone; Midazolam; Phenobarbital; Substance Withdrawal Syndrome; Substance-Related Disorders | 1994 |
Flumazenil as a diagnostic tool in the differential diagnosis of coma in a critically ill patient.
Topics: Aged; Bacterial Infections; Coma; Critical Illness; Diagnosis, Differential; Diazepam; Flumazenil; Hepatic Encephalopathy; Humans; Lorazepam; Male; Midazolam | 1994 |
Controlling high-cost drug use.
Topics: Child; Cost Control; Drug Costs; Humans; Intensive Care Units, Pediatric; Lorazepam; Midazolam; Pharmacy Service, Hospital; Premedication; Technology, High-Cost | 1994 |
Promotion of cost-effective benzodiazepine sedation.
Topics: Cost Control; Critical Care; Education, Medical, Continuing; Humans; Lorazepam; Midazolam | 1993 |
Compatibility of midazolam hydrochloride and lorazepam with selected drugs during simulated Y-site administration.
Topics: Anti-Anxiety Agents; Chemical Precipitation; Drug Incompatibility; Humans; Hydrogen-Ion Concentration; Hypnotics and Sedatives; Lorazepam; Midazolam; Pharmaceutical Preparations | 1995 |
Stability of deferoxamine mesylate, floxuridine, fluorouracil, hydromorphone hydrochloride, lorazepam, and midazolam hydrochloride in polypropylene infusion-pump syringes.
Topics: Chromatography, High Pressure Liquid; Deferoxamine; Drug Stability; Fluorouracil; Hydromorphone; Infusion Pumps; Lorazepam; Midazolam; Polypropylenes; Syringes; Time Factors | 1996 |
High-performance liquid chromatographic determination of midazolam in rat brain.
Topics: Animals; Anti-Anxiety Agents; Brain Chemistry; Chromatography, High Pressure Liquid; Diazepam; Disease Models, Animal; Injections, Intravenous; Linear Models; Lorazepam; Midazolam; Rats; Reproducibility of Results; Status Epilepticus | 1996 |
Benzodiazepines differentially inhibit phenylephrine-induced calcium oscillations in pulmonary artery smooth muscle cells.
Topics: Adrenergic alpha-Agonists; Animals; Benzodiazepines; Calcium; Cells, Cultured; Diazepam; Dogs; Lorazepam; Male; Midazolam; Muscle, Smooth, Vascular; Periodicity; Phenylephrine; Pulmonary Artery; Signal Transduction | 1998 |
A cost analysis of enterally administered lorazepam in the pediatric intensive care unit.
Topics: Child; Child, Preschool; Cost-Benefit Analysis; Critical Illness; Drug Costs; Female; Hospital Costs; Humans; Hypnotics and Sedatives; Infant; Infusions, Intravenous; Intensive Care Units, Pediatric; Intubation, Gastrointestinal; Lorazepam; Male; Midazolam; Retrospective Studies; Time Factors; Utah | 1999 |
In vitro evaluation of sedative drug losses during extracorporeal membrane oxygenation.
Topics: Biocompatible Materials; Child, Preschool; Diazepam; Extracorporeal Membrane Oxygenation; Humans; Hypnotics and Sedatives; Infant; Lorazepam; Midazolam; Polyvinyl Chloride; Propofol; Silicones | 2000 |
Developmentally based care reduces stress levels in severely ill, very low birth weight (VLBW) infants, and thus decreases sedation requirements.
Topics: Chloral Hydrate; Conscious Sedation; Humans; Hypnotics and Sedatives; Infant, Newborn; Infant, Very Low Birth Weight; Lorazepam; Midazolam; Stress, Physiological | 1999 |
Management of acute psychosis.
Topics: Acute Disease; Benzodiazepines; Health Services Accessibility; Humans; Injections, Intramuscular; Lorazepam; Midazolam; Psychotic Disorders | 2000 |
Pharmacokinetic-pharmacodynamic modeling and ICU sedation: unexplored territories.
Topics: Algorithms; Conscious Sedation; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Midazolam; Models, Biological; Pharmacokinetics | 2001 |
Useful information about the pharmacokinetics and pharmacodynamics of midazolam and lorazepam.
Topics: Humans; Hypnotics and Sedatives; Lorazepam; Midazolam | 2002 |
Anxiolysis in general dental practice.
Topics: Acetamides; Adjuvants, Anesthesia; Anesthesia, Dental; Anesthetics, Inhalation; Anti-Anxiety Agents; Clinical Protocols; Conscious Sedation; Dental Anxiety; Diazepam; GABA Modulators; General Practice, Dental; Humans; Hydroxyzine; Hypnotics and Sedatives; Lorazepam; Midazolam; Nitrous Oxide; Pyrimidines; Triazolam | 2003 |
Preprocedural fasting state and adverse events in children undergoing procedural sedation and analgesia in a pediatric emergency department.
Topics: Adjuvants, Anesthesia; Analgesia; Anesthetics, Combined; Child; Child, Preschool; Chloral Hydrate; Conscious Sedation; Diazepam; Emergency Treatment; Fasting; Fentanyl; Guideline Adherence; Humans; Hypnotics and Sedatives; Hypotension; Hypoxia; Ketamine; Laryngismus; Lorazepam; Midazolam; Nitrous Oxide; Patient Selection; Pediatrics; Pentobarbital; Practice Guidelines as Topic; Prospective Studies; Risk Factors; Vomiting | 2003 |
Rotation of propofol and midazolam for long-term sedation.
Topics: Drug Administration Schedule; Humans; Hypnotics and Sedatives; Lorazepam; Midazolam; Propofol; Time Factors | 2004 |
Paradoxical vocal cord motion: an often misdiagnosed cause of postoperative stridor.
Topics: Airway Obstruction; Anesthetics, Intravenous; Diagnosis, Differential; Female; Fiber Optic Technology; Humans; Laryngoscopy; Lorazepam; Midazolam; Middle Aged; Postoperative Complications; Respiratory Sounds; Vocal Cords | 2004 |
Population pharmacokinetics of lorazepam and midazolam and their metabolites in intensive care patients on continuous venovenous hemofiltration.
Topics: Acute Kidney Injury; Adult; Aged; Conscious Sedation; Drug Administration Schedule; Drug Evaluation; Female; Hemofiltration; Humans; Lorazepam; Male; Metabolic Clearance Rate; Midazolam; Middle Aged; Models, Theoretical; Multiple Organ Failure; Respiration, Artificial; Ventilators, Mechanical | 2005 |
Pharmacoeconomic modeling of lorazepam, midazolam, and propofol for continuous sedation in critically ill patients.
Topics: Costs and Cost Analysis; Critical Illness; Decision Support Techniques; Economics, Pharmaceutical; Humans; Hypnotics and Sedatives; Lorazepam; Midazolam; Propofol | 2005 |
[Management of status epilepticus].
Topics: Adult; Age Factors; Aged; Anti-Anxiety Agents; Anticonvulsants; Benzodiazepines; Child; Diazepam; Drug Therapy, Combination; Electroencephalography; Humans; Infant; Infant, Newborn; Lorazepam; Midazolam; Phenobarbital; Phenytoin; Prognosis; Propofol; Randomized Controlled Trials as Topic; Status Epilepticus | 2005 |
Addition of dexmedetomidine to standard sedation regimens after cardiac surgery: an outcomes analysis.
Topics: Aged; Cardiac Surgical Procedures; Dexmedetomidine; Drug Therapy, Combination; Female; Hospitals; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Lorazepam; Male; Midazolam; Middle Aged; Outcome Assessment, Health Care; Propofol; Retrospective Studies | 2006 |
Canadian radiology residents' knowledge of sedation and analgesia: a web-based survey.
Topics: Analgesia; Anesthetics; Anesthetics, Intravenous; Anesthetics, Local; Bupivacaine; Canada; Conscious Sedation; Data Collection; Diazepam; Fentanyl; Humans; Hypnotics and Sedatives; Internet; Internship and Residency; Lidocaine; Lorazepam; Midazolam; Radiology; Surveys and Questionnaires; Time Factors | 2006 |
Pain management of first-trimester surgical abortion: effects of selection of local anesthesia with and without lorazepam or intravenous sedation.
Topics: Abortion, Induced; Adult; Analgesia; Anesthetics; Female; Fentanyl; Humans; Ibuprofen; Lorazepam; Midazolam; Pain Measurement; Pain, Postoperative; Patient Satisfaction; Pregnancy; Pregnancy Trimester, First; Prospective Studies; Regression Analysis | 2006 |
The birth of the NETT: NIH-funded network will launch emergency neurological trials.
Topics: Anticonvulsants; Clinical Trials as Topic; Emergency Medical Services; Humans; Informed Consent; Lorazepam; Midazolam; Multicenter Studies as Topic; National Institutes of Health (U.S.); Nervous System Diseases; Seizures; United States | 2006 |
Changes in relative potency among positive GABA(A) receptor modulators upon discontinuation of chronic benzodiazepine treatment in rhesus monkeys.
Topics: Animals; Behavior, Animal; Benzodiazepines; Diazepam; Discrimination Learning; Dose-Response Relationship, Drug; Female; Flumazenil; GABA Modulators; Lorazepam; Macaca mulatta; Male; Midazolam; Pentobarbital; Pregnanediones; Pregnanolone; Receptors, GABA-A; Substance Withdrawal Syndrome | 2007 |
Symptom-driven lorazepam protocol for treatment of severe alcohol withdrawal delirium in the intensive care unit.
Topics: Alcohol Withdrawal Delirium; Anti-Anxiety Agents; Benzodiazepines; Clinical Protocols; Drug Administration Schedule; Female; Half-Life; Hospitalization; Hospitals, Veterans; Humans; Infusions, Intravenous; Injections, Intravenous; Intensive Care Units; Length of Stay; Lorazepam; Male; Midazolam; Middle Aged; Propanolamines; Retrospective Studies; Surveys and Questionnaires; Treatment Outcome | 2007 |
Inadequate provision of postintubation anxiolysis and analgesia in the ED.
Topics: Adult; Aged; Analgesics, Opioid; Anti-Anxiety Agents; Anxiety; Cohort Studies; Emergency Service, Hospital; Female; Fentanyl; Humans; Hypnotics and Sedatives; Intubation, Intratracheal; Lorazepam; Male; Midazolam; Middle Aged; Pain; Retrospective Studies | 2008 |
Use of palliative sedation for intractable symptoms in the palliative care unit of a comprehensive cancer center.
Topics: Adult; Aged; Aged, 80 and over; Cancer Care Facilities; Chlorpromazine; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Midazolam; Middle Aged; Neoplasms; Palliative Care; Practice Patterns, Physicians'; Retrospective Studies; Young Adult | 2009 |
Status epilepticus in central nervous system infections: an experience from a developing country.
Topics: Adolescent; Adult; Aged; Anticonvulsants; Central Nervous System Infections; Developing Countries; Diazepam; Drug Resistance; Electroencephalography; Female; Hospitals, Teaching; Humans; India; Lorazepam; Magnetic Resonance Imaging; Male; Midazolam; Middle Aged; Phenytoin; Prospective Studies; Status Epilepticus; Valproic Acid | 2008 |
Neonatal allopregnanolone increases novelty-directed locomotion and disrupts behavioural responses to GABA(A) receptor modulators in adulthood.
Topics: Animals; Animals, Newborn; Behavior, Animal; Brain; Dose-Response Relationship, Drug; Drug Administration Schedule; Drug Interactions; Exploratory Behavior; Flumazenil; GABA Modulators; Isoxazoles; Lorazepam; Male; Maze Learning; Midazolam; Motor Activity; Pregnanolone; Rats; Rats, Wistar; Receptors, GABA-A | 2009 |
Evaluation of adult outpatient magnetic resonance imaging sedation practices: are patients being sedated optimally?
Topics: Adult; Ambulatory Care; Anti-Anxiety Agents; Conscious Sedation; Data Collection; Diazepam; Drug Utilization; Humans; Lorazepam; Magnetic Resonance Imaging; Midazolam | 2009 |
Guidelines for diagnosis and management of childhood epilepsy.
Topics: Algorithms; Anticonvulsants; Child; Child, Preschool; Diazepam; Electroencephalography; Epilepsy; Humans; India; Infant; Infant, Newborn; Lorazepam; Midazolam; Pediatrics; Phenytoin; Pyridoxine | 2009 |
Profound reduction in sedation and analgesic requirements using extended dexmedetomidine infusions in a patient with an open abdomen.
Topics: Abdominal Injuries; Analgesics, Non-Narcotic; Dexmedetomidine; Fentanyl; Humans; Infusions, Intravenous; Lorazepam; Male; Midazolam; Military Personnel; Pain Measurement; Propofol; Stress Disorders, Post-Traumatic; Wounds, Gunshot; Young Adult | 2009 |
Simultaneous determination and quantification of 12 benzodiazepines in serum or whole blood using UPLC/MS/MS.
Topics: Alprazolam; Benzodiazepines; Chlordiazepoxide; Chromatography, Liquid; Clonazepam; Flunitrazepam; Humans; Lorazepam; Midazolam; Nordazepam; Oxazepam; Reproducibility of Results; Tandem Mass Spectrometry | 2010 |
Diazepam as a component of goal-directed sedation in critically ill trauma patients.
Topics: Adult; APACHE; Critical Illness; Diazepam; Drug Interactions; Drug Therapy, Combination; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Lorazepam; Male; Midazolam; Prospective Studies; Respiration, Artificial; Wounds and Injuries | 2011 |
Cases of catatonia on an academic electroconvulsive therapy service: lessons to learn.
Topics: Aged; Aged, 80 and over; Anxiety Disorders; Catatonia; Depressive Disorder; Depressive Disorder, Major; Electroconvulsive Therapy; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Midazolam; Middle Aged; Psychiatric Status Rating Scales; Psychotic Disorders | 2011 |
Determination of illegally abused sedative-hypnotics in hair samples from drug offenders.
Topics: Adult; Diazepam; Gas Chromatography-Mass Spectrometry; Hair; Humans; Hypnotics and Sedatives; Illicit Drugs; Limit of Detection; Lorazepam; Male; Midazolam; Middle Aged; Pyridines; Substance Abuse Detection; Young Adult; Zolpidem | 2011 |
Awareness during cardiac surgery--a single-centre prospective clinical audit of 1060 patients.
Topics: Adjuvants, Anesthesia; Androstanols; Anesthetics, Inhalation; Awareness; Cardiac Surgical Procedures; Etomidate; Fentanyl; Humans; Hypnotics and Sedatives; Isoflurane; Lorazepam; Male; Medical Audit; Mental Recall; Midazolam; Middle Aged; Neuromuscular Nondepolarizing Agents; Pancuronium; Propofol; Prospective Studies; Rocuronium; Temazepam; Vecuronium Bromide | 2011 |
Withdrawal treatment with clonidine after prolonged use of chloral hydrate in a pediatric intensive care patient.
Topics: Adrenergic alpha-Agonists; Analgesics, Opioid; Chloral Hydrate; Clonidine; Fentanyl; Humans; Hypnotics and Sedatives; Infant; Intensive Care, Neonatal; Lorazepam; Male; Methadone; Midazolam; Pneumonia; Respiratory Insufficiency; Substance Withdrawal Syndrome | 2011 |
Reversible delirium in an advanced cancer patient.
Topics: Amines; Analgesics; Analgesics, Opioid; Bone Neoplasms; Breast Neoplasms; Carcinoma, Intraductal, Noninfiltrating; Carcinoma, Lobular; Cyclohexanecarboxylic Acids; Delirium; Disease Progression; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Gabapentin; gamma-Aminobutyric Acid; Humans; Lorazepam; Midazolam; Middle Aged; Neoplasm Staging; Neoplasms, Multiple Primary; Palliative Care; Spinal Neoplasms | 2012 |
Intramuscular versus intravenous benzodiazepines for prehospital treatment of status epilepticus.
Topics: Anticonvulsants; Emergency Medical Services; Female; Humans; Infusions, Intravenous; Injections, Intramuscular; Lorazepam; Male; Midazolam; Status Epilepticus | 2012 |
Benzodiazepines for acute management of seizures.
Topics: Diazepam; Female; Humans; Lorazepam; Male; Midazolam; Seizures | 2012 |
Intramuscular versus intravenous benzodiazepines for status epilepticus.
Topics: Anticonvulsants; Emergency Medical Services; Female; Humans; Infusions, Intravenous; Injections, Intramuscular; Lorazepam; Male; Midazolam; Status Epilepticus | 2012 |
Intramuscular versus intravenous benzodiazepines for status epilepticus.
Topics: Anticonvulsants; Emergency Medical Services; Female; Humans; Infusions, Intravenous; Injections, Intramuscular; Lorazepam; Male; Midazolam; Status Epilepticus | 2012 |
Treatment of status epilepticus: an international survey of experts.
Topics: Administration, Intravenous; Adult; Anticonvulsants; Child; Consensus; Expert Testimony; Humans; Hypnotics and Sedatives; Levetiracetam; Lorazepam; Midazolam; Pentobarbital; Phenytoin; Piracetam; Propofol; Societies, Medical; Status Epilepticus; Surveys and Questionnaires; Valproic Acid | 2013 |
Dexmedetomidine to treat lisdexamfetamine overdose and serotonin toxidrome in a 6-year-old girl.
Topics: Adrenergic alpha-2 Receptor Agonists; Anti-Anxiety Agents; Central Nervous System Stimulants; Child; Dexmedetomidine; Dextroamphetamine; Drug Overdose; Female; Humans; Lisdexamfetamine Dimesylate; Lorazepam; Midazolam; Serotonin Syndrome | 2012 |
Propofol is associated with favorable outcomes compared with benzodiazepines in ventilated intensive care unit patients.
Topics: Adult; Aged; Anesthetics, Intravenous; Benzodiazepines; Cohort Studies; Critical Care; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Lorazepam; Male; Midazolam; Middle Aged; Nursing Research; Propofol; Respiration, Artificial; Retrospective Studies; Survival Rate; Tracheostomy; Treatment Outcome; Utah | 2014 |
Comparison of clinical outcomes in nonintubated patients with severe alcohol withdrawal syndrome treated with continuous-infusion sedatives: dexmedetomidine versus benzodiazepines.
Topics: Adult; Aged; Benzodiazepines; Cohort Studies; Dexmedetomidine; Ethanol; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lorazepam; Male; Midazolam; Middle Aged; Retrospective Studies; Severity of Illness Index; Substance Withdrawal Syndrome; Treatment Outcome | 2014 |
Prescribing patterns of the four most commonly used sedatives in endoscopic examination in Korea: propofol, midazolam, diazepam, and lorazepam.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Diazepam; Drug Prescriptions; Drug Utilization Review; Endoscopy; Female; Health Care Surveys; Humans; Hypnotics and Sedatives; Lorazepam; Male; Midazolam; Middle Aged; Patient Selection; Practice Patterns, Physicians'; Propofol; Republic of Korea; Risk Assessment; Risk Factors; Substance-Related Disorders; Time Factors; Young Adult | 2015 |
Increased use in propofol and reported patterns of adverse events among anesthetics in Korea.
Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Anesthetics, Intravenous; Child; Child, Preschool; Diazepam; Drug Utilization Review; Drug-Related Side Effects and Adverse Reactions; Female; Humans; Infant; Infant, Newborn; Lorazepam; Male; Midazolam; Middle Aged; Propofol; Republic of Korea; Risk Assessment; Risk Factors; Substance-Related Disorders; Time Factors; Young Adult | 2015 |
Exception from informed consent: ethics and logistics.
Topics: Allied Health Personnel; Anticonvulsants; Clinical Trials as Topic; Emergency Service, Hospital; Female; Humans; Informed Consent; Lorazepam; Male; Midazolam; Research Design; Status Epilepticus; Third-Party Consent | 2015 |
Histomorphometric analysis of salivary gland in wistar rats treated chronically with two benzodiazepines.
Topics: Acinar Cells; Animals; Benzodiazepines; Dose-Response Relationship, Drug; Drug Therapy, Combination; Lorazepam; Male; Midazolam; Muscarinic Agonists; Parotid Gland; Pilocarpine; Rats; Rats, Wistar; Treatment Outcome | 2015 |
Practice variability and efficacy of clonazepam, lorazepam, and midazolam in status epilepticus: A multicenter comparison.
Topics: Adult; Aged; Aged, 80 and over; Anticonvulsants; Benzodiazepines; Clonazepam; Cohort Studies; Female; Humans; Lorazepam; Male; Midazolam; Middle Aged; Practice Patterns, Physicians'; Prospective Studies; Status Epilepticus; Treatment Outcome | 2015 |
Comparison of short-term effects of midazolam and lorazepam in the intra-amygdala kainic acid model of status epilepticus in mice.
Topics: Amygdala; Animals; Anticonvulsants; Benzodiazepines; Disease Models, Animal; Hippocampus; Kainic Acid; Lorazepam; Male; Mice; Mice, Inbred C57BL; Midazolam; Status Epilepticus; Treatment Outcome | 2015 |
Making SENSE--Sustained Effort Network for treatment of Status Epilepticus as a multicenter prospective registry.
Topics: Adult; Aged; Anticonvulsants; Diazepam; Female; Humans; Lorazepam; Male; Midazolam; Middle Aged; Phenytoin; Prospective Studies; Registries; Status Epilepticus | 2015 |
Outcomes of Patients with Alcohol Withdrawal Syndrome Treated with High-Dose Sedatives and Deferred Intubation.
Topics: Adult; Alcohol Withdrawal Seizures; APACHE; Central Nervous System Depressants; Cohort Studies; Critical Illness; Dexmedetomidine; Ethanol; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Intubation, Intratracheal; Length of Stay; Logistic Models; Lorazepam; Male; Midazolam; Middle Aged; Pneumonia; Propofol; Respiration, Artificial; Retrospective Studies; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome | 2016 |
Look again at psychedelic drugs.
Topics: Anxiety; Delirium; Depression; Diazepam; Hallucinogens; Haloperidol; Humans; Lorazepam; Midazolam; Pharmaceutical Research; Psychomotor Agitation; United Kingdom | 2016 |
Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose.
Topics: Adult; Carisoprodol; Dexmedetomidine; Drug Overdose; Fentanyl; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Units; Ketamine; Lorazepam; Male; Midazolam; Propofol; Quetiapine Fumarate; Respiration, Artificial; Substance Withdrawal Syndrome; Substance-Related Disorders | 2017 |
Case Report of Midazolam Withdrawal-Induced Catatonia in a 9-Year-Old Patient.
Topics: Catatonia; Child; Drug Administration Schedule; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units, Pediatric; Lorazepam; Male; Midazolam; Postoperative Care; Risk Factors; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome | 2017 |
Evaluation of IV to Enteral Benzodiazepine Conversion Calculations in a Pediatric Intensive Care Setting.
Topics: Airway Extubation; Child, Preschool; Diazepam; Drug Dosage Calculations; Drug Substitution; Female; Humans; Hypnotics and Sedatives; Infant; Infusions, Intravenous; Intensive Care Units, Pediatric; Lorazepam; Midazolam; Quality Improvement; Respiration, Artificial; Retrospective Studies; Substance Withdrawal Syndrome | 2018 |
Emergency Medical Services Protocols for Generalized Convulsive Status Epilepticus.
Topics: Administration, Intravenous; Anticonvulsants; California; Clinical Protocols; Diazepam; Emergency Medical Services; Humans; Injections, Intramuscular; Lorazepam; Midazolam; Practice Guidelines as Topic; Status Epilepticus | 2019 |
Development of a Korean-specific virtual population for physiologically based pharmacokinetic modelling and simulation.
Topics: Adult; Asian People; Computer Simulation; Cytochrome P-450 Enzyme System; Female; Glucuronosyltransferase; Humans; Liver-Specific Organic Anion Transporter 1; Lorazepam; Male; Metoprolol; Midazolam; Middle Aged; Models, Biological; Omeprazole; Rosuvastatin Calcium; Software; Warfarin; Young Adult | 2019 |
Comparison of intranasal midazolam versus intravenous lorazepam for seizure termination and prevention of seizure clusters in the adult epilepsy monitoring unit.
Topics: Administration, Intranasal; Administration, Intravenous; Adult; Anticonvulsants; Epilepsy; Female; Hospitalization; Humans; Lorazepam; Male; Midazolam; Middle Aged; Retrospective Studies; Seizures; Status Epilepticus | 2019 |
Comparative safety profile of chloral hydrate versus other sedatives for procedural sedation in hospitalized infants.
Topics: Chloral Hydrate; Diagnostic Imaging; Diagnostic Techniques, Ophthalmological; Electroencephalography; Female; Gestational Age; Hospitalization; Humans; Hypnotics and Sedatives; Infant; Infant, Newborn; Logistic Models; Lorazepam; Male; Midazolam; Multivariate Analysis; Oxygen Inhalation Therapy; Pentobarbital; Polysomnography; Propensity Score; Respiration, Artificial; Respiratory Insufficiency | 2020 |
Statewide Emergency Medical Services Protocols for Status Epilepticus Management.
Topics: Administration, Intranasal; Administration, Rectal; Adult; Anticonvulsants; Benzodiazepines; Child; Cross-Sectional Studies; Diazepam; Emergency Medical Services; Humans; Injections, Intramuscular; Injections, Intravenous; Levetiracetam; Lorazepam; Midazolam; Phenobarbital; Practice Guidelines as Topic; Status Epilepticus; United States | 2021 |
Prehospital Treatment of Status Epilepticus in the United States.
Topics: Anticonvulsants; Benzodiazepines; Diazepam; Emergency Medical Services; Guideline Adherence; Humans; Lorazepam; Midazolam; Practice Guidelines as Topic; Status Epilepticus; United States | 2021 |
Midazolam with haloperidol versus lorazepam with haloperidol for agitation: Effect on emergency department lengths of stay.
Topics: Antipsychotic Agents; Drug Therapy, Combination; Emergency Service, Hospital; Haloperidol; Humans; Lorazepam; Midazolam; Psychomotor Agitation | 2022 |
Clearance of Lormetazepam, Midazolam, and Their Conjugated Metabolites by Continuous Venovenous Hemofiltration During Prolonged Sedation in Critically Ill Patients With COVID-19-Associated Acute Respiratory Distress Syndrome.
Topics: Aged; Continuous Renal Replacement Therapy; COVID-19; COVID-19 Drug Treatment; Critical Illness; Deep Sedation; Humans; Hypnotics and Sedatives; Lorazepam; Male; Midazolam; Middle Aged; Respiratory Distress Syndrome | 2022 |
Prospective study of haloperidol plus lorazepam versus droperidol plus midazolam for the treatment of acute agitation in the emergency department.
Topics: Antipsychotic Agents; Droperidol; Emergency Service, Hospital; Haloperidol; Humans; Lorazepam; Midazolam; Prospective Studies; Psychomotor Agitation | 2022 |
Enteral lorazepam is a promising weaning strategy for midazolam-responsive febrile infection-related epilepsy syndrome (FIRES): a case series
Topics: Child; Drug Resistant Epilepsy; Encephalitis; Epileptic Syndromes; Humans; Lorazepam; Male; Midazolam; Retrospective Studies; Weaning | 2022 |
The Midazolam RAMPART Study Medical Records Project: A Unique Use of Real-World Data in a Complex Collaborative Partnership to Support a New Drug Application.
Topics: Clinical Trials as Topic; Humans; Lorazepam; Medical Records; Midazolam; Retrospective Studies; Status Epilepticus; United States | 2023 |
Comparison of Droperidol and Midazolam Versus Haloperidol and Lorazepam for Acute Agitation Management in the Emergency Department.
Topics: Antipsychotic Agents; Droperidol; Emergency Service, Hospital; Haloperidol; Humans; Injections, Intramuscular; Lorazepam; Midazolam; Psychomotor Agitation; Retrospective Studies | 2023 |
Using Interdisciplinary Teams to Mitigate the Effects of Drug Shortages in Palliative Care: The Case of Lorazepam Injection.
Topics: Benzodiazepines; Humans; Lorazepam; Midazolam; Palliative Care | 2023 |