lorazepam has been researched along with lormetazepam in 178 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 110 (61.80) | 18.7374 |
| 1990's | 23 (12.92) | 18.2507 |
| 2000's | 24 (13.48) | 29.6817 |
| 2010's | 14 (7.87) | 24.3611 |
| 2020's | 7 (3.93) | 2.80 |
| Authors | Studies |
|---|---|
| Babbini, M; Barbaro, AM; Bartoletti, M; Biagi, GL; Borea, PA; Gaiardi, M; Guerra, MC | 1 |
| Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| Hümpel, M; Illi, V; Kurowski, M; Milius, W; Wendt, H | 1 |
| Jähnig, P; Jobert, M; Kubicki, S; Poiseau, E; Schulz, H | 2 |
| Doyle, D; Kragie, L | 1 |
| Doenicke, A; Dorow, R; Täuber, U | 1 |
| Akai, T; Nakada, Y; Ozawa, M; Sugimachi, K; Yamaguchi, M | 1 |
| Andrews, JS; Jensen, LH; Kehr, W; Petersen, EN; Rettig, KJ; Schmiechen, R; Schneider, HH; Stephens, DN; Turner, JD; Turski, L | 1 |
| Doenicke, A; Greim, M; Juhl, G; Rampf, U; Suttmann, H | 1 |
| Hellenbrecht, D; Hellstern, A; Hildebrand, M; Hümpel, M; Madetzki, C; Saller, R | 1 |
| Brookhuis, KA; O'Hanlon, JF; Volkerts, ER | 1 |
| Deijen, JB; Heemstra, ML; Orlebeke, JF | 1 |
| de Haan, P; Rettig, HC; von Leeuwen, L; Zuurmond, WW | 1 |
| Schneider, HH; Stephens, DN; Weidmann, R; Zimmermann, L | 1 |
| Schneider, HH; Stephens, DN; Zimmermann, LN | 2 |
| De Leo, D | 1 |
| Adam, K; Oswald, I | 3 |
| Klotz, U | 1 |
| Schneider, HH; Stephens, DN | 2 |
| Wildmann, J | 1 |
| Sarter, M; Schneider, HH | 1 |
| Bixler, EO; Jacoby, JA; Kales, A; Kales, JD; Soldatos, CR | 1 |
| Vernay, A; Vu Duc, T | 1 |
| Hossain, M; Joseph, DN | 1 |
| Fujiwara, M; Iwasaki, K; Liou, SY; Ohta, H; Sakurai, Y; Shibata, K; Shibata, S; Ueki, S; Watanabe, S; Yamamoto, T | 1 |
| Ceccarelli, G; Ciampini, M; Ferrario, P; Fraschini, F; Pirola, R; Reina, L; Scaglione, F; Zecca, L | 1 |
| Ferrario, P; Fraschini, F; Pirola, R; Zambotti, F; Zecca, L; Zonta, N | 1 |
| Beaumont, G; Chima, P | 1 |
| Griffiths, AN; Jones, DM; Richens, A | 1 |
| Kubicki, S; Meyer, C; Röhmel, J | 1 |
| Camu, F; Claeys, MA | 1 |
| John, SM; McCarthy, GL; McCarthy, ST; Wollner, L | 1 |
| Grabe, N; Hansen, W; Jakobsen, CJ; Jensen, JJ | 1 |
| Ackenheil, M; Doenicke, A; Dorow, R; Duka, T; Noderer, J | 1 |
| Ceccarelli, G; de Leo, D | 1 |
| Hartung, M; Hettenbach, A; Krug, C; Tolksdorf, W | 1 |
| Groves, ND; Rees, JL; Rosen, M | 1 |
| Brüssel, T; Heinecke, A; Meinshausen, E; Prien, T; Van Aken, H | 1 |
| Haag, C; Herrmann, WM; Höller, L; Kubicki, S | 1 |
| Berenberg, D; Dorow, R; Duka, T; Sauerbrey, N | 1 |
| Barry, H; Bewley, A; Fox, E; McCreary, C; O'Boyle, CA | 1 |
| Dorow, R; Duka, T; Fichte, K; Goerke, D; Höller, L | 1 |
| Alford, CA; Bhatti, JZ; Hindmarch, I | 1 |
| Aufdembrinke, B; Fichte, K; Ott, H; Rohloff, A | 1 |
| Collard, E; Gribomont, BF; Scholtes, JL; Van Boven, MJ; Van Obbergh, L | 1 |
| Rees, J; Robinson, JO; Rosen, M; Sanders, LD; Yeomans, WA | 1 |
| Benkert, O; Heuser, I; Wetzel, H | 1 |
| Takahashi, S | 1 |
| Haroon, TS; Jafferany, M | 1 |
| Haag-Wüsthof, C; Herrmann, WM; Kubicki, S; Röhmel, J; Scheuler, W | 1 |
| Richards, HH; Vallé-Jones, CJ | 1 |
| Weppner, GJ | 1 |
| Oldman, PN; Overstall, PW | 1 |
| Hart, DM; Hughes, RR; Laing, M | 1 |
| Eichinger, V; Heipertz, W; Hempel, V; Vontin, H | 1 |
| Barbieri, MR; Bove, R; Lestingi, L; Maltese, A; Meco, G | 1 |
| Doenicke, A; Dorow, R; Duka, T; Klotz, U | 1 |
| Morgan, K | 2 |
| Jung, M; Kappa, E; Manegold, BC; Müller, HP; Schratzer, M; Tolksdorf, W | 1 |
| de Thier, D; Machowsky, R; Mantanus, H; Rousseau, JC; Timsit-Berthier, M | 1 |
| Baldock, GA; Chasseaud, LF; Girkin, R; Hawkins, DR; Hümpel, M; Mayo, BC | 1 |
| Chasseaud, LF; Girkin, R; Hawkins, DR; Hümpel, M; Mayo, BC | 1 |
| Hanke, H; Hümpel, M; Milius, W; Nieuweboer, B; Wendt, H | 1 |
| Beach, RC; Heidrich, H; Ott, H | 1 |
| Huempel, M; Kampf, D; Kessel, M; Lerche, U | 1 |
| Fichte, K; Hentschel, HD; Sastre y Hernández, M | 1 |
| Fichte, K; Hentschel, HD; Sastre y Hernández, MS | 1 |
| Fernández Labriola, R; Fichte, K; Satre y Hernández, M | 1 |
| Doom, A; Ibarra, M; Mundeleer, P | 1 |
| Bruwier, M | 1 |
| Doenicke, A; Fichte, K; Grote, B; Kugler, J; Laub, M; Ott, H; Suttmann, H; Zwisler, P | 1 |
| Nicholson, AN; Stone, BM | 1 |
| Dorow, RG; Schneider, HH; Seidler, J | 1 |
| Adam, K; French, C; Gilham, J; Oswald, I | 1 |
| Ulsamer, B | 1 |
| Hümpel, M; Milia, S; Rainer, E; Stoppelli, I | 1 |
| Fichte, K; Paschelke, G; Sastre-y-Hernández, M; Vass, K | 1 |
| Fitz, H; Schütz, H | 1 |
| Fichte, K; Sastre-y-Hernández, M; Studer, A | 1 |
| Herrmann, WM; Kurowski, M; Ott, H | 1 |
| Carskadon, M; Dement, W; Seidel, W | 1 |
| Baruzzi, A; Cirignotta, F; De Anna, M; Gallassi, R; Soverini, S; Zucconi, M | 1 |
| Franke, N; Kemkes, B; Laubenthal, H; Schmucker, P; van Ackern, K; Vogel, H; Weber, W | 1 |
| Dorow, R; Horowski, R | 1 |
| Seyberth, HW | 1 |
| Oswald, I | 1 |
| Ansseau, M; Diricq, S | 1 |
| Doenicke, A; Ott, H; Suttmann, H; Ulsamer, B | 1 |
| Hindmarch, I; Subhan, Z | 2 |
| Fichte, K; Pöldinger, W; Sastre-y-Hernández, M | 1 |
| Camera, A; Gherardi, S; Maxia, D; Moja, EA; Scamonatti, L | 1 |
| Kubicki, S; Scheuler, W; Stinshoff, D | 1 |
| Fichte, K; Hemmerling, KG; Neubert, W; Ott, H; Schratzer, M; Willumeit, HP | 1 |
| Di Perri, R | 1 |
| Franklin, RA; Harry, TV; Nicholson, AN; Pierce, DM | 1 |
| Ott, H | 1 |
| Kranda, K; Kulikowski, JJ; McGlone, FF; Ott, H | 1 |
| Koshorek, G; McLenaghan, A; Roehrs, T; Roth, T; Zorick, F | 1 |
| Subhan, Z | 1 |
| Neubert, W; Ott, H; Willumeit, HP | 1 |
| Vogel, GW | 1 |
| Luscombe, DK | 1 |
| Doenicke, A; Lorenz, W | 1 |
| Guilleminault, C | 1 |
| Harry, TV; Hill, RC | 1 |
| Melo de Paula, AJ | 1 |
| Doenicke, A | 1 |
| Azanza Perea, JR; Cuena Boy, R; Honorato Pérez, J; Rubio González, A | 1 |
| Fitzal, S; Groll-Knapp, E; Länger, W; Riegler, R | 1 |
| Biondi, A; Carone, AR; De Marino, V; De Natale, G | 1 |
| Hertrich, O | 1 |
| Hemmerling, KG; Neubert, W; Ott, H; Willumeit, HP | 1 |
| Hempelmann, G; Kling, D; Kramer, M; Scheld, HH; von Bormann, B | 1 |
| Ammermann, C; Bahro, M; Marcus, A; Schmidt, MH | 1 |
| Boonkerd, S; Detaevernier, MR; Michotte, Y; Vindevogel, J | 1 |
| Gaillard, P; Jähnig, P; Jobert, M; Poiseau, E; Schulz, H | 1 |
| Cluydts, R; Cosyns, P; De Roeck, J; Lacante, P | 1 |
| Bouvy, PF; Duivenvoorden, HJ; Haffmans, PM; Nolen, WA | 1 |
| Bahro, M; Marcus, A; Sartoris, J; Schmidt, MH | 1 |
| Doenicke, A; Lorenz, W; Mayer, M; Nebauer, AE; Peter, K; Rosenberger, C | 1 |
| Avanzini, P; Caccavari, R; Chittolini, B; Delsignore, R; Fertonani, G; Gerra, G; Giucasto, G; Zaimovic, A | 1 |
| Bouvy, PF; de Groot, MH; Huijsman, AM; Nolen, WA | 1 |
| Nováková, E | 1 |
| Dimpfel, W; Hofmann, HC; Schober, F; Todorova, A | 1 |
| Augsburger, M; Mangin, P; Rivier, L | 1 |
| Baudry, F; Douceron, H; Hassnaoui, S; Marc, B; Vaquero, P; Zerrouki, L | 1 |
| Christiaens, F; Dellers, I; Denis, B; Lessire, H; Vankeerberghen, L; Verborgh, C | 1 |
| Afschrift, M; Mariman, A; Petrovic, M; Pevernagie, D; Van Maele, G | 1 |
| Berzas Nevado, JJ; Castañeda Peñalvo, G; Pinilla Calderón, MJ | 1 |
| Bonanni, E; Brotini, S; Iudice, A; Iudice, G; Maestri, M; Manca, L; Murri, L; Nucciarone, B | 1 |
| Baghai, T; Berger, M; Cohrs, S; Fischer, W; Hajak, G; Hoffmann, M; Hohagen, F; Laakmann, G; Mayer, G; Riemann, D; Rodenbeck, A; Rüther, E; Voderholzer, U; Wiegand, MH | 1 |
| Curtin, F; Redmund, C | 1 |
| Kamei, C; Mio, M; Okuma, C; Shigemoto, Y; Shinomiya, K | 1 |
| Allain, H; Bentué-Ferrer, D; Gandon, JM; Tarral, A | 1 |
| Alquier, C; Ancolio, C; Blin, O; Micallef, J; Pradel, V; Soubrouillard, C; Tardieu, S | 1 |
| Benedetti, F; Bernasconi, A; Colombo, C; Florita, M; Pontiggia, A; Smeraldi, E | 1 |
| Bonanni, E; Fabbrini, M; Frittelli, C; Iudice, A; Maestri, M; Manca, ML | 1 |
| Arnal, MA; Boeijinga, P; Ertlé, S; Luthringer, R; Muzet, A; Rinaudo, G; Staner, L | 1 |
| Aguglia, E; De Vanna, M; Onor, ML; Rubiera, M | 1 |
| Lemmer, P; Mühe, A; Schneider, S; Wennig, R | 1 |
| Kamei, C; Nishino, T; Takechi, K; Takeuchi, T | 1 |
| Gómez-Grande, ML; Martín-Rodríguez, C; Ortega-Carnicer, J; Portilla-Botelho, M | 1 |
| Backhaus, J; Hohagen, F; Hüppe, M; Junghanns, K; Katofsky, I; Rumpf, HJ; von Eitzen, U | 1 |
| Roth, T; Verster, JC | 1 |
| Fraile, S; García, B; Hidalgo, FJ; Lopez, E | 1 |
| De Picker, L; Sabbe, B; Schrijvers, D; van Ham, C; Vandendriessche, F | 1 |
| Alladio, E; Leardi, R; Pirro, V; Salomone, A; Vincenti, M | 1 |
| Casari, R; Cosci, F; Faccini, M; Lugoboni, F; Mansueto, G | 1 |
| Chaslot, M; Delage, M; Dulaurent, S; El Balkhi, S; Mathieu, O; Picard, N; Saint-Marcoux, F | 1 |
| Barceló Martín, B; Gilabert Iriondo, N; Gomila Muñiz, I; López-Corominas, V | 1 |
| Lugoboni, F; Zamboni, L; Zandonai, T | 2 |
| Casari, R; Faccini, M; Lugoboni, F; Morbioli, L; Tamburin, S | 1 |
| Balon, R; Chouinard, G; Cosci, F; Nardi, AE; Starcevic, V | 1 |
| Ferini-Strambi, L; Galbiati, A; Sforza, M | 1 |
| Lugoboni, F; Tamburin, S | 1 |
| Andresen-Streichert, H; Froch-Cortis, J; Lehmann, S; Mercer-Chalmers-Bender, K; Rothschild, MA; Sczyslo, A; Thevis, M | 1 |
| Falcon, M; Fernadez-Lopez, L; Luna, A; Mancini, R; Pellegrini, M; Rotolo, M | 1 |
| Horowski, R | 1 |
| Casari, R; Costa, E; Lugoboni, F; Marini, P; Sterzi, E; Tedeschi, F | 1 |
| Horikoshi, S; Hoshino, H; Kanno, K; Miura, I; Ochiai, H; Osakabe, Y; Shiga, T; Yabe, H | 1 |
| Foudraine, N; Janssen, PKC; le Noble, JLML; Shudofsky, KN | 1 |
5 review(s) available for lorazepam and lormetazepam
| Article | Year |
|---|---|
Rebound insomnia and elimination half-life: assessment of individual subject response.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Flurazepam; Half-Life; Humans; Lorazepam; Midazolam; Middle Aged; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Time Factors; Triazolam | 1985 |
Lormetazepam, memory and information processing: a review.
Topics: Anti-Anxiety Agents; Benzodiazepines; Humans; Lorazepam; Memory; Mental Processes | 1988 |
Modern trends in the investigation of new hypnotics in anaesthesia.
Topics: Anesthesia; Anti-Anxiety Agents; Arousal; Benzodiazepines; Electroencephalography; Electrophysiology; Flunitrazepam; Half-Life; Humans; Hypnotics and Sedatives; Lorazepam; Midazolam; Psychometrics | 1984 |
Gender differences in highway driving performance after administration of sleep medication: a review of the literature.
Topics: Acetamides; Automobile Driving; Azabicyclo Compounds; Environment Design; Female; Flurazepam; Humans; Hypnotics and Sedatives; Indenes; Lorazepam; Male; Piperazines; Psychomotor Performance; Pyridines; Pyrimidines; Sex Factors; Sleep Wake Disorders; Zolpidem | 2012 |
Dependence liability of lormetazepam: are all benzodiazepines equal? The case of the new i.v. lormetazepam for anesthetic procedures.
Topics: Anesthetics; Anti-Anxiety Agents; Benzodiazepines; Humans; Lorazepam; Male | 2020 |
79 trial(s) available for lorazepam and lormetazepam
| Article | Year |
|---|---|
Topographical analysis of sleep spindle activity.
Topics: Adult; Aged; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Brain Mapping; Double-Blind Method; Electroencephalography; Evoked Potentials; Female; Frontal Lobe; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Parietal Lobe; Piperazines; Polysomnography; Reaction Time; Signal Processing, Computer-Assisted; Sleep Initiation and Maintenance Disorders; Sleep Stages | 1992 |
Pattern recognition by matched filtering: an analysis of sleep spindle and K-complex density under the influence of lormetazepam and zopiclone.
Topics: Adult; Aged; Anti-Anxiety Agents; Arousal; Azabicyclo Compounds; Benzodiazepines; Cerebral Cortex; Double-Blind Method; Electroencephalography; Evoked Potentials; Female; Fourier Analysis; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Piperazines; Polysomnography; Signal Processing, Computer-Assisted; Sleep Initiation and Maintenance Disorders | 1992 |
[The pharmacokinetics of lormetazepam following cimetidine].
Topics: Anti-Anxiety Agents; Benzodiazepines; Cimetidine; Female; Humans; Lorazepam; Male | 1991 |
[Beta activation following the intravenous administration of benzodiazepines and the specific antagonist flumazenil (Ro 15-1788)].
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Beta Rhythm; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Flumazenil; Flunitrazepam; Humans; Injections, Intravenous; Lorazepam; Male; Midazolam; Prospective Studies; Randomized Controlled Trials as Topic; Stimulation, Chemical | 1990 |
Repeated dose effects of lormetazepam and flurazepam upon driving performance.
Topics: Adult; Anti-Anxiety Agents; Automobile Driving; Benzodiazepines; Double-Blind Method; Female; Flurazepam; Humans; Lorazepam; Male; Psychomotor Performance; Sleep | 1990 |
Residual effects of lormetazepam on mood and performance in healthy elderly volunteers.
Topics: Affect; Aged; Aging; Anti-Anxiety Agents; Benzodiazepines; Cognition; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Memory; Psychomotor Performance | 1991 |
Effects of hypnotics on sleep and psychomotor performance. A double-blind randomised study of lormetazepam, midazolam and zopiclone.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Midazolam; Middle Aged; Piperazines; Psychomotor Performance; Sleep; Time Factors | 1990 |
Treatment of adjustment disorders: a comparative evaluation.
Topics: Adjustment Disorders; Administration, Oral; Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Female; Humans; Injections, Intramuscular; Lorazepam; Male; Morpholines; Psychoanalytic Therapy; Random Allocation; S-Adenosylmethionine; Viloxazine | 1989 |
Can a rapidly-eliminated hypnotic cause daytime anxiety?
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Body Weight; Dreams; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Sleep; Triazolam | 1989 |
Rebound insomnia and elimination half-life: assessment of individual subject response.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, Drug; Double-Blind Method; Flurazepam; Half-Life; Humans; Lorazepam; Midazolam; Middle Aged; Sleep Initiation and Maintenance Disorders; Substance Withdrawal Syndrome; Time Factors; Triazolam | 1985 |
Transfer of long term insomniac nitrazepam users to lormetazepam.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Chronic Disease; Double-Blind Method; Female; Humans; Lorazepam; Male; Middle Aged; Nitrazepam; Sleep; Sleep Initiation and Maintenance Disorders | 1986 |
Zopiclone produces effects on human performance similar to flurazepam, lormetazepam and triazolam.
Topics: Adult; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Cognition; Double-Blind Method; Emotions; Flurazepam; Humans; Hypnotics and Sedatives; Lorazepam; Male; Memory; Mental Processes; Piperazines; Psychomotor Performance; Random Allocation; Reaction Time; Saccades; Triazolam | 1986 |
[The 4 second sleep spindle periodicity].
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Double-Blind Method; Electroencephalography; Evoked Potentials; Flunitrazepam; Humans; Lorazepam; Methaqualone; Middle Aged; Pentobarbital; Periodicity; Random Allocation; Sleep Stages; Triazolam; Urea | 1986 |
Efficacy of lorazepam and lormetazepam as intravenous premedicants for anesthesia and surgery.
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Female; Hemodynamics; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Muscle Tonus; Preanesthetic Medication; Psychomotor Performance; Random Allocation | 1986 |
Oral lormetazepam in premedication. A comparison with diazepam.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Drug Evaluation; Female; Humans; Lorazepam; Male; Preanesthetic Medication | 1986 |
Changes in noradrenaline plasma levels and behavioural responses induced by benzodiazepine agonists with the benzodiazepine antagonist Ro 15-1788.
Topics: Adult; Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Blood Pressure; Double-Blind Method; Electrocardiography; Electroencephalography; Flumazenil; Flunitrazepam; Humans; Lorazepam; Male; Norepinephrine; Random Allocation | 1986 |
Antianxiety properties of lormetazepam. A double-blind crossover trial versus diazepam.
Topics: Adult; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans; Lorazepam; Male; Middle Aged | 1986 |
[Effect and side effects of oral morphine, lormetazepam and placebos as premedication].
Topics: Administration, Oral; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Clinical Trials as Topic; Depression; Dilatation and Curettage; Female; Hemodynamics; Humans; Intraoperative Complications; Lorazepam; Morphine; Pain, Postoperative; Placebos; Preanesthetic Medication; Random Allocation | 1987 |
[Hemodynamics under propofol-nitrous oxide anesthesia: effects of premedication with lormetazepam and of additional fentanyl].
Topics: Anesthesia; Anesthetics; Anti-Anxiety Agents; Benzodiazepines; Blood Pressure; Cardiac Output; Fentanyl; Heart Rate; Hemodynamics; Humans; Lorazepam; Nitrous Oxide; Phenols; Preanesthetic Medication; Propofol | 1987 |
Amnestic effects of lormetazepam and their reversal by the benzodiazepine antagonist Ro 15-1788.
Topics: Adult; Amnesia; Anti-Anxiety Agents; Benzodiazepines; Cognition; Emotions; Female; Flumazenil; Humans; Lorazepam; Male; Memory | 1987 |
Controlled comparison of a new sublingual lormetazepam formulation and i.v. diazepam in outpatient minor oral surgery.
Topics: Administration, Sublingual; Adult; Ambulatory Surgical Procedures; Anesthesia, Dental; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Drug Evaluation; Hemodynamics; Humans; Infusions, Intravenous; Lorazepam; Memory; Patient Acceptance of Health Care; Preanesthetic Medication; Tooth, Impacted | 1988 |
Human studies on the benzodiazepine receptor antagonist beta-carboline ZK 93 426: antagonism of lormetazepam's psychotropic effects.
Topics: Adult; Anti-Anxiety Agents; Anticonvulsants; Arousal; Benzodiazepines; Blood Pressure; Carbolines; Electroencephalography; Heart Rate; Humans; Lorazepam; Male; Psychomotor Performance; Receptors, GABA-A; Reinforcement Schedule; Sleep; Time Perception | 1988 |
Anterograde and retrograde amnesia after lormetazepam and flunitrazepam.
Topics: Amnesia; Amnesia, Retrograde; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Emotions; Flunitrazepam; Humans; Lorazepam; Male; Memory; Psychomotor Performance; Time Factors | 1988 |
A new lormetazepam galenical formulation for sublingual premedication.
Topics: Administration, Sublingual; Adult; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Lorazepam; Memory; Preanesthetic Medication | 1988 |
A double-blind comparison between nitrazepam, lorazepam, lormetazepam and placebo as preoperative night sedatives.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Humans; Lorazepam; Middle Aged; Nitrazepam; Placebos; Preanesthetic Medication; Sleep | 1988 |
A double-blind comparison of two lormetazepam doses in elderly insomniacs.
Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Random Allocation; Sleep Initiation and Maintenance Disorders; Sleep Stages | 1988 |
A comparative study of lormetazepam and chlormethiazole in elderly in-patients.
Topics: Aged; Aged, 80 and over; Aging; Anti-Anxiety Agents; Benzodiazepines; Chlormethiazole; Clinical Trials as Topic; Double-Blind Method; Humans; Lorazepam; Male; Sleep Initiation and Maintenance Disorders | 1987 |
Lormetazepam or triazolam as night sedation before surgery.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Female; Humans; Lorazepam; Premedication; Sleep; Triazolam | 1986 |
[Plasma concentration and amnesia following lormetazepam and flunitrazepam in i.v. premedication].
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Female; Flunitrazepam; Humans; Infusions, Parenteral; Kinetics; Lorazepam; Male; Memory; Mental Recall; Middle Aged; Pattern Recognition, Visual; Preanesthetic Medication; Random Allocation; Retention, Psychology | 1986 |
A double-blind controlled subjective study of a new pharmaceutical preparation of lormetazepam versus placebo in patients with chronic sleep disturbances.
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Humans; Hypnotics and Sedatives; Lorazepam; Middle Aged; Random Allocation; Sleep Wake Disorders; Surveys and Questionnaires; Time Factors | 1985 |
Flunitrazepam and lormetazepam do not affect the pharmacokinetics of the benzodiazepine antagonist Ro 15-1788.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Flumazenil; Flunitrazepam; Humans; Kinetics; Lorazepam; Male | 1985 |
Effects of repeated dose nitrazepam and lormetazepam on psychomotor performance in the elderly.
Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Female; Humans; Lorazepam; Male; Nitrazepam; Psychomotor Disorders | 1985 |
[Intravenous sedation before endoscopic interventions. Comparative study of lormetazepam and diazepam in oil].
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Cholangiopancreatography, Endoscopic Retrograde; Diazepam; Female; Humans; Hypnotics and Sedatives; Injections, Intravenous; Lorazepam; Male; Middle Aged; Premedication | 1985 |
Sleep and wake after benzodiazepine hypnotics: a 20-hour EEG comparison of lormetazepam and flunitrazepam.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Electroencephalography; Female; Flunitrazepam; Half-Life; Humans; Hypnotics and Sedatives; Kinetics; Lorazepam; Male; Random Allocation; Sleep; Sleep Stages; Spectrum Analysis; Time Factors; Wakefulness | 1985 |
Benzodiazepines cause small loss of body weight.
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Body Weight; Female; Humans; Lorazepam; Male; Middle Aged; Nitrazepam | 1980 |
Lormetazepam - a benzodiazepine derivative without hangover effect? A double-blind study with chronic insomniacs in a general practice setting.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Electroencephalography; Humans; Lorazepam; Middle Aged; Placebos; Sleep Initiation and Maintenance Disorders | 1981 |
[Lormetazepam in the treatment of sleep disorders in a medical practice; double-blind test on 100 patients (author's transl)].
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Double-Blind Method; Female; Humans; Lorazepam; Male; Middle Aged; Sleep Wake Disorders | 1981 |
Comparative efficacy of lormetazepam (Noctamid) and diazepam (Valium) in 100 out-patients with insomnia.
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Humans; Lorazepam; Male; Middle Aged; Sleep Initiation and Maintenance Disorders | 1981 |
[Comparison of lormetazepam, flunitrazepam and placebo in a long-term effect and long-term tolerance study in 105 patients with chronic sleep disorders].
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Drug Tolerance; Female; Flunitrazepam; Humans; Lorazepam; Male; Middle Aged; Placebos; Sleep Wake Disorders | 1981 |
Lormetazepam - yet another benzodiazepine.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Humans; Lorazepam | 1982 |
Hypnotic activity and effects on performance of lormetazepam and camazepam--analogues of temazepam.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Cognition; Emotions; Humans; Hypnotics and Sedatives; Lorazepam; Male; Motor Skills; Sleep; Sleep Stages; Structure-Activity Relationship; Temazepam | 1982 |
A radioreceptor assay to study the affinity of benzodiazepines and their receptor binding activity in human plasma including their active metabolites.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Biotransformation; Blood Proteins; Diazepam; Female; Humans; Lorazepam; Male; Nitrazepam; Nordazepam; Protein Binding; Radioligand Assay; Receptors, Drug; Receptors, GABA-A | 1982 |
Benzodiazepine hypnotics remain effective for 24 weeks.
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Dreams; Female; Humans; Lorazepam; Male; Middle Aged; Nitrazepam; Sleep Initiation and Maintenance Disorders; Time Factors; Wakefulness | 1982 |
[Measuring anxiolysis in anesthesia].
Topics: Anesthesia, Spinal; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Humans; Lorazepam | 1981 |
[Drug therapy of sleep disorders in shift workers].
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Lorazepam; Middle Aged; Occupational Diseases; Random Allocation; Sleep Wake Disorders; Time Factors | 1982 |
[Comparison of lormetazepam and flunitrazepam in general practice (author's transl)].
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Female; Flunitrazepam; Humans; Lorazepam; Male; Middle Aged; Random Allocation; Sleep Initiation and Maintenance Disorders | 1982 |
[Double-blind comparison of lormetazepam and flurazepam in the treatment of patients with insomnia].
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Female; Flurazepam; Humans; Lorazepam; Male; Middle Aged; Sleep Initiation and Maintenance Disorders | 1982 |
Lormetazepam and amobarbital sodium in the outpatient treatment of insomnia: a controlled trial.
Topics: Adult; Amobarbital; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Outpatients; Sleep Initiation and Maintenance Disorders | 1983 |
[Preoperative anxiolysis with lormetazepam. A model for measuring anxiety].
Topics: Adult; Aged; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Humans; Lorazepam; Middle Aged; Models, Psychological; Preoperative Care | 1983 |
The effects of lormetazepam on aspects of sleep and early morning performance.
Topics: Adult; Anti-Anxiety Agents; Attention; Benzodiazepines; Female; Flicker Fusion; Humans; Lorazepam; Middle Aged; Psychomotor Performance; Reaction Time; Sleep; Time Factors | 1983 |
Study with lormetazepam as a hypnotic in general practice.
Topics: Adolescent; Adult; Aged; Ambulatory Care; Anti-Anxiety Agents; Benzodiazepines; Family Practice; Female; Humans; Lorazepam; Male; Middle Aged; Sleep Wake Disorders; Triazolam | 1983 |
Double-blind evaluation of the safety and hypnotic efficacy of lormetazepam in general practice.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Family Practice; Female; Humans; Lorazepam; Male; Middle Aged; Sleep Wake Disorders | 1983 |
Are electroencephalographic and psychomotor measures sensitive in detecting residual sequelae of benzodiazepine hypnotics?
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Double-Blind Method; Electroencephalography; Female; Flunitrazepam; Half-Life; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Psychomotor Performance; Radioligand Assay; Sleep | 1984 |
Are the amplitudes of visual evoked potentials sensitive indices of hangover effects after repeated doses of benzodiazepines?
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Cognition; Electrodes; Evoked Potentials, Visual; Flurazepam; Humans; Lorazepam; Perception; Placebos; Reaction Time | 1984 |
Amnesic effects of lormetazepam.
Topics: Adolescent; Adult; Amnesia; Anti-Anxiety Agents; Attention; Benzodiazepines; Double-Blind Method; Electrophysiology; Flurazepam; Humans; Hypnotics and Sedatives; Lorazepam; Male; Memory; Mental Recall; Sleep; Temazepam | 1984 |
Sleep laboratory study of lormetazepam in older insomniacs.
Topics: Aged; Aging; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Electrophysiology; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Sleep; Sleep Initiation and Maintenance Disorders; Sleep Stages; Sleep, REM | 1984 |
Effects of two benzodiazepines on the speed and accuracy of perceptual-motor performance in the elderly.
Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Nitrazepam; Perception; Psychomotor Performance | 1984 |
Effects of zopiclone and benzodiazepine hypnotics on search in short-term memory.
Topics: Adult; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Female; Flunitrazepam; Humans; Lorazepam; Memory, Short-Term; Piperazines; Reaction Time; Triazolam | 1984 |
Lormetazepam (Lorámet): a multicentre assessment of its efficacy and acceptability as a hypnotic in out-patients with sleep disturbances.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Outpatients; Sleep Wake Disorders | 1983 |
Comparative study of lormetazepam and flurazepam in the treatment of insomnia.
Topics: Adult; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Clinical Trials as Topic; Dose-Response Relationship, Drug; Female; Flurazepam; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Sleep Initiation and Maintenance Disorders | 1984 |
[Premedication with flunitrazepam, lormetazepam or pethidine-promethazine. Psychometric study of subjective conditions].
Topics: Adult; Amnesia; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Depression; Emotions; Flunitrazepam; Humans; Hypnotics and Sedatives; Lorazepam; Meperidine; Middle Aged; Preoperative Care; Promethazine; Psychometrics | 1983 |
ECG activity in the sleep of insomniac patients under the influence of lormetazepam and zopiclone.
Topics: Aged; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Electrocardiography; Female; Heart Rate; Humans; Hypnotics and Sedatives; Lorazepam; Male; Piperazines; Polysomnography; Sleep; Sleep Initiation and Maintenance Disorders; Sleep Stages | 1995 |
Antagonizing the effects of experimentally induced sleep disturbance in healthy volunteers by lormetazepam and zolpidem.
Topics: Adult; Anti-Anxiety Agents; Attention; Benzodiazepines; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Mental Recall; Neuropsychological Tests; Noise, Transportation; Polysomnography; Psychomotor Performance; Pyridines; Reaction Time; Sleep Initiation and Maintenance Disorders; Sleep Stages; Zolpidem | 1995 |
Hypnotics as concurrent medication in depression. A placebo-controlled, double-blind comparison of flunitrazepam and lormetazepam in patients with major depression, treated with a (tri)cyclic antidepressant.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Flunitrazepam; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Placebos; Plasma; Severity of Illness Index; Sleep Wake Disorders; Sleep, REM | 1993 |
[Pharmacodynamics and clinical adverse effects of mivacurium. The effect of oral premedication with H1/H2 antagonists].
Topics: Administration, Oral; Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Dimethindene; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Isoquinolines; Lorazepam; Male; Middle Aged; Mivacurium; Neuromuscular Nondepolarizing Agents; Preanesthetic Medication; Ranitidine | 1993 |
Intravenous flumazenil following prolonged exposure to lormetazepam in humans: lack of precipitated withdrawal.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Flumazenil; GABA Modulators; Humans; Injections, Intravenous; Lorazepam; Male; Substance Withdrawal Syndrome | 1996 |
Lateralized neuropsychological functioning in depressive patients before and after drug therapy.
Topics: Adult; Aged; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Cognition; Depressive Disorder; Female; Flunitrazepam; Functional Laterality; Humans; Lorazepam; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales | 1996 |
Validation of an EEG-derived spectral frequency index (SFx) for continuous monitoring of sleep depth in humans.
Topics: Adult; Algorithms; Anti-Anxiety Agents; Benzodiazepines; Cross-Over Studies; Electroencephalography; Female; Fourier Analysis; Humans; Hypnotics and Sedatives; Lorazepam; Male; Polysomnography; Reproducibility of Results; Retrospective Studies; Single-Blind Method; Sleep Stages | 1998 |
Fast withdrawal from benzodiazepines in geriatric inpatients: a randomised double-blind, placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Alcoholism; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Female; Humans; Lorazepam; Male; Patient Dropouts; Sleep; Substance Withdrawal Syndrome; Surveys and Questionnaires; Treatment Outcome | 2002 |
Lormetazepam effects on daytime vigilance, psychomotor performance and simulated driving in young adult healthy volunteers.
Topics: Adult; Anti-Anxiety Agents; Automobile Driving; Benzodiazepines; Computer Simulation; Cross-Over Studies; Double-Blind Method; Female; Humans; Lorazepam; Male; Psychomotor Performance; Sleep; Sleep Stages | 2002 |
Trimipramine in primary insomnia: results of a polysomnographic double-blind controlled study.
Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Polysomnography; Sleep Initiation and Maintenance Disorders; Sleep Stages; Sleep, REM; Treatment Outcome; Trimipramine | 2002 |
Effects on postural oscillation and memory functions of a single dose of zolpidem 5 mg, zopiclone 3.75 mg and lormetazepam 1 mg in elderly healthy subjects. A randomized, cross-over, double-blind study versus placebo.
Topics: Aged; Attention; Azabicyclo Compounds; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Memory; Piperazines; Placebos; Postural Balance; Psychomotor Performance; Pyridines; Reaction Time; Sensation Disorders; Sleep; Zolpidem | 2003 |
A randomized clinical trial comparing doses and efficacy of lormetazepam tablets or oral solution for insomnia in a general practice setting.
Topics: Administration, Oral; Adult; Analysis of Variance; Family Practice; Female; Humans; Lorazepam; Male; Middle Aged; Pharmaceutical Solutions; Sleep Initiation and Maintenance Disorders; Tablets | 2004 |
Lormetazepam in depressive insomnia: new evidence of phase-response effects of benzodiazepines.
Topics: Administration, Oral; Adult; Aged; Cross-Over Studies; Depressive Disorder; Drug Administration Schedule; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Placebos; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2004 |
Psychomotor performance in healthy young adult volunteers receiving lormetazepam and placebo: a single-dose, randomized, double-blind, crossover trial.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Psychomotor Performance; Reaction Time; Time Factors | 2005 |
Next-day residual effects of hypnotics in DSM-IV primary insomnia: a driving simulator study with simultaneous electroencephalogram monitoring.
Topics: Adult; Arousal; Automobile Driving; Azabicyclo Compounds; Circadian Rhythm; Computer Simulation; Diagnostic and Statistical Manual of Mental Disorders; Double-Blind Method; Electroencephalography; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Piperazines; Pyridines; Sleep Initiation and Maintenance Disorders; Zolpidem | 2005 |
Role of lormetazepam in the treatment of insomnia in the elderly.
Topics: Aged; Combined Modality Therapy; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Sleep; Sleep Initiation and Maintenance Disorders | 2007 |
Effectiveness of a cognitive behavioral self-help program for patients with primary insomnia in general practice - a pilot study.
Topics: Cognitive Behavioral Therapy; Combined Modality Therapy; Female; General Practice; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Pilot Projects; Sleep Initiation and Maintenance Disorders; Treatment Outcome | 2012 |
Effects of benzodiazepine and orexin receptor antagonist on cognitive function revealed by auditory event-related potentials.
Topics: Adult; Auditory Perception; Azepines; Benzodiazepines; Cognitive Dysfunction; Discrimination, Psychological; Electroencephalography; Event-Related Potentials, P300; Evoked Potentials, Auditory; Female; Humans; Lorazepam; Male; Orexin Receptor Antagonists; Triazoles; Young Adult | 2021 |
95 other study(ies) available for lorazepam and lormetazepam
| Article | Year |
|---|---|
Rm values and structure-activity relationship of benzodiazepines.
Topics: Animals; Benzodiazepines; Chromatography, Thin Layer; Conflict, Psychological; Exploratory Behavior; Models, Biological; Rats; Solubility; Structure-Activity Relationship | 1980 |
ElogPoct: a tool for lipophilicity determination in drug discovery.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
The pharmacokinetics and biotransformation of the new benzodiazepine lormetazepam in humans. I. Absorption, distribution, elimination and metabolism of lormetazepam-5-14C.
Topics: Absorption; Adult; Anti-Anxiety Agents; Benzodiazepines; Biotransformation; Feces; Glucuronates; Humans; Kinetics; Lorazepam; Male; Time Factors; Tissue Distribution | 1979 |
Benzodiazepines inhibit temperature-dependent L-[125I]triiodothyronine accumulation into human liver, human neuroblast, and rat pituitary cell lines.
Topics: Adenoma; Animals; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Cell Line; Convulsants; Diazepam; Dose-Response Relationship, Drug; Humans; Iodine Radioisotopes; Liver; Lorazepam; Neuroblastoma; Pituitary Neoplasms; Rats; Receptors, Thyroid Hormone; Temperature; Triazolam; Triiodothyronine; Tritium; Tumor Cells, Cultured | 1992 |
[Interaction of the hypnotic lormetazepam with central benzodiazepine receptor subtypes omega 1, omega 2 and omega 3].
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Dose-Response Relationship, Drug; Drug Interactions; Lorazepam; Male; Mice; Motor Activity; Muscle Relaxation; Receptors, GABA-A; Reflex; Sleep | 1991 |
Abecarnil, a metabolically stable, anxioselective beta-carboline acting at benzodiazepine receptors.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Diazepam; Female; Lorazepam; Male; Mice; Motor Activity; Punishment; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1990 |
Minimal biliary excretion and enterohepatic recirculation of lormetazepam in man as investigated by a new nasobiliary drainage technique.
Topics: Adult; Aged; Aged, 80 and over; Anti-Anxiety Agents; Benzodiazepines; Bile; Biotransformation; Cholestasis; Enterohepatic Circulation; Female; Glucuronates; Humans; Lorazepam; Male; Middle Aged | 1990 |
Decreased sensitivity to benzodiazepine receptor agonists and increased sensitivity to inverse agonists following chronic treatments: evidence for separate mechanisms.
Topics: Animals; Anti-Anxiety Agents; Appetite Depressants; Benzodiazepines; Carbolines; Chlorides; Diazepam; Drug Interactions; Drug Tolerance; Exploratory Behavior; Ion Channels; Kindling, Neurologic; Locomotion; Lorazepam; Mice; Muscimol; Pentylenetetrazole; Rats; Receptors, GABA-A | 1988 |
Partial GABA agonist activity of SR 95531 on the binding of [35S]TBPS, [3H]DMCM and [3H]lormetazepam to rat brain membranes.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Bridged-Ring Compounds; Carbolines; GABA Antagonists; gamma-Aminobutyric Acid; In Vitro Techniques; Lorazepam; Male; Pyridazines; Rats; Rats, Inbred Strains; Receptors, GABA-A | 1989 |
Binding characteristics reveal partial GABA agonist activities of SR 95531.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Lorazepam; Pyridazines; Rats; Receptors, GABA-A | 1989 |
Drug interactions and clinical pharmacokinetics of flumazenil.
Topics: Anti-Anxiety Agents; Benzodiazepines; Biological Availability; Drug Interactions; Ethanol; Flumazenil; Flunitrazepam; Half-Life; Humans; Liver; Lorazepam; Midazolam; Receptors, GABA-A; Tomography, Emission-Computed | 1988 |
Co-existence of kindling induced by the beta-carboline, FG 7142, and tolerance to diazepam following chronic treatment in mice.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Carbolines; Diazepam; Drug Tolerance; Female; Kindling, Neurologic; Lorazepam; Mice; Motor Activity; Punishment; Receptors, GABA-A; Seizures | 1988 |
Increase of natural benzodiazepines in wheat and potato during germination.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Brain; Cell Membrane; Chromatography, High Pressure Liquid; Diazepam; Gas Chromatography-Mass Spectrometry; Lorazepam; Plant Development; Plants; Rats; Receptors, GABA-A; Solanum tuberosum; Triticum | 1988 |
High density of benzodiazepine binding sites in the substantia innominata of the rat.
Topics: Animals; Anti-Anxiety Agents; Autoradiography; Basal Ganglia; Benzodiazepines; Brain; Kinetics; Lorazepam; Male; Organ Specificity; Rats; Rats, Inbred Strains; Receptors, GABA-A; Substantia Innominata; Tritium | 1988 |
[Validation of a method for detecting benzodiazepines in the urine by acid extraction of their benzophenones and thin layer chromatography].
Topics: Anti-Anxiety Agents; Benzodiazepines; Benzophenones; Bromazepam; Chromatography, Gas; Chromatography, Thin Layer; Clonazepam; Diazepam; Humans; Hydrogen-Ion Concentration; Hydrolysis; Lorazepam; Nitrazepam | 1985 |
Lormetazepam (Loramet) in the elderly: an acceptability study.
Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Dreams; Drug Evaluation; Female; Humans; Lorazepam; Male; Middle Aged; Sleep; Sleep Initiation and Maintenance Disorders; Time Factors; Wakefulness | 1985 |
[Behavioral and electroencephalographic effects of lormetazepam].
Topics: Anesthetics; Animals; Anti-Anxiety Agents; Anticonvulsants; Behavior, Animal; Benzodiazepines; Brain; Drug Synergism; Electroencephalography; Lorazepam; Male; Methamphetamine; Mice; Psychomotor Performance; Rabbits; Rats; Rats, Inbred Strains | 1985 |
Relative bioavailability in humans for oral tablets and solutions of lormetazepam.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Benzodiazepines; Biological Availability; Chromatography, Gas; Half-Life; Humans; Intestinal Absorption; Kinetics; Lorazepam; Male; Solutions; Tablets | 1985 |
Determination of lormetazepam in plasma by gas chromatography and electron-capture detection.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Chromatography, Gas; Electrochemistry; Humans; Indicators and Reagents; Kinetics; Lorazepam; Male | 1986 |
The influence of chlormethiazole in comparison to thioridazine on body temperature and postural hypotension in healthy adults and healthy elderly volunteers.
Topics: Adult; Age Factors; Aged; Anti-Anxiety Agents; Benzodiazepines; Blood Pressure; Body Temperature Regulation; Chlormethiazole; Female; Humans; Lorazepam; Male; Posture; Skin Temperature; Thioridazine | 1986 |
Two more hypnotics added to the 'White List'.
Topics: Aged; Aged, 80 and over; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Humans; Lorazepam | 1987 |
Effects of benzodiazepines on laryngeal reflexes. Comparison of lormetazepam and Diazemuls.
Topics: Adolescent; Adult; Ammonia; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Humans; Larynx; Lorazepam; Psychomotor Performance; Reflex; Time Factors | 1987 |
On the distribution of REM and NREM sleep under two benzodiazepines with comparable receptor affinity but different kinetic properties.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Electroencephalography; Female; Humans; Lorazepam; Male; Middle Aged; Random Allocation; Receptors, GABA-A; Retrospective Studies; Sleep Stages; Sleep, REM; Triazolam | 1987 |
Benzodiazepines for catatonic symptoms, stupor, and mutism.
Topics: Anti-Anxiety Agents; Benzodiazepines; Catatonia; Depressive Disorder; Diazepam; Female; Flumazenil; Humans; Lorazepam; Mutism | 1988 |
Isotope effect in negative ion chemical ionization mass spectrometry of deuterium labelled lormetazepam.
Topics: Anti-Anxiety Agents; Benzodiazepines; Deuterium; Gas Chromatography-Mass Spectrometry; Isotope Labeling; Lorazepam; Temperature | 1987 |
Fixed drug eruption with lormetazepam (Noctamid)
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Drug Eruptions; Humans; Hypnotics and Sedatives; Lorazepam; Male | 1988 |
Tolerance to the benzodiazepine diazepam in an animal model of anxiolytic activity.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Carbolines; Diazepam; Drug Tolerance; Female; gamma-Aminobutyric Acid; Lorazepam; Male; Mice; Punishment; Receptors, GABA-A | 1985 |
[Effect of lormetazepam, triazolam and flunitrazepam on rapid eye movements, K-complexes and sleep spindles in normal probands].
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Electroencephalography; Female; Flunitrazepam; Humans; Lorazepam; Male; Middle Aged; Sleep; Sleep, REM; Triazolam | 1987 |
The effect of benzodiazepine withdrawal on the dexamethasone suppression test.
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Dexamethasone; Double-Blind Method; Female; Humans; Hydrocortisone; Lorazepam; Male; Middle Aged; Triazolam | 1988 |
The absorption, distribution and excretion of [14C]lormetazepam in dogs, rabbits, rats and rhesus monkeys.
Topics: Absorption; Animals; Anti-Anxiety Agents; Benzodiazepines; Carbon Radioisotopes; Dogs; Female; Lorazepam; Macaca mulatta; Pregnancy; Rabbits; Rats; Species Specificity; Tissue Distribution | 1980 |
The biotransformation of [14C]lormetazepam in dogs, rabbits, rats and rhesus monkeys.
Topics: Animals; Anti-Anxiety Agents; Benzodiazepines; Bile; Biotransformation; Carbon Radioisotopes; Chromatography, Thin Layer; Dogs; Female; Lorazepam; Macaca mulatta; Mass Spectrometry; Maternal-Fetal Exchange; Pregnancy; Rabbits; Radioimmunoassay; Rats; Species Specificity | 1980 |
Kinetics and biotransformation of lormetazepam. II. Radioimmunologic determinations in plasma and urine of young and elderly subjects: first-pass effect.
Topics: Adult; Age Factors; Aged; Anti-Anxiety Agents; Benzodiazepines; Biotransformation; Female; Glucuronates; Half-Life; Humans; Kinetics; Lorazepam; Male; Metabolic Clearance Rate; Radioimmunoassay | 1980 |
Effects of uremia and hemodialysis on lormetazepam disposition.
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Biotransformation; Female; Glucuronates; Humans; Kinetics; Lorazepam; Male; Middle Aged; Renal Dialysis; Uremia | 1981 |
Pre- and postoperative use of lormetazepam.
Topics: Anti-Anxiety Agents; Benzodiazepines; Bone and Bones; Double-Blind Method; Dreams; Female; Humans; Lorazepam; Male; Postoperative Care; Preoperative Care; Sleep; Sleep Wake Disorders | 1981 |
[Clinical study of lormetazepam (WY-4082) in patients at a geriatric hospital].
Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Drug Evaluation; Female; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Random Allocation; Sleep Wake Disorders | 1981 |
[The antagonistic effect of physostigmine on sedation by lormetazepam (author's transl)].
Topics: Anti-Anxiety Agents; Arousal; Benzodiazepines; Electroencephalography; Humans; Lorazepam; Male; Physostigmine; Sleep Stages; Statistics as Topic; Time Factors | 1981 |
Pharmacokinetics and biotransformation of the new benzodiazepine, lormetazepam, in man. III. Repeated administration and transfer to neonates via breast milk.
Topics: Anti-Anxiety Agents; Benzodiazepines; Biotransformation; Breast Feeding; Female; Glucuronates; Humans; Infant, Newborn; Kinetics; Lorazepam; Milk, Human | 1982 |
[Screening, detection and biotransformation of lormetazepam, a new hypnotic agent from the 1,4-benzodiazepine series (author's transl)].
Topics: Anti-Anxiety Agents; Benzodiazepines; Biotransformation; Chromatography, Thin Layer; Drug Evaluation, Preclinical; Humans; Hypnotics and Sedatives; Lorazepam | 1982 |
Relationship between EEG dynamics and pharmacokinetics of the benzodiazepine lormetazepam.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Arousal; Attention; Benzodiazepines; Double-Blind Method; Electroencephalography; Evoked Potentials; Half-Life; Humans; Lorazepam; Male; Metabolic Clearance Rate | 1982 |
Daytime alertness, insomnia, and benzodiazepines.
Topics: Adult; Anti-Anxiety Agents; Arousal; Benzodiazepines; Double-Blind Method; Flurazepam; Humans; Lorazepam; Male; Oxazepam; Sleep Deprivation; Sleep Initiation and Maintenance Disorders; Sleep Stages; Triazolam; Wakefulness | 1982 |
[Effect of the intravenous administration of lormetazepam on hemodynamics and arterial blood gases in patients with coronary heart disease].
Topics: Anti-Anxiety Agents; Benzodiazepines; Blood Gas Analysis; Blood Pressure; Carbon Dioxide; Coronary Disease; Hemodynamics; Humans; Injections, Intravenous; Lorazepam; Middle Aged; Oxygen Consumption | 1982 |
[Significance of pharmacokinetic findings for the clinical effect of benzodiazepines].
Topics: Anti-Anxiety Agents; Benzodiazepines; Biological Availability; Chemical Phenomena; Chemistry; Diazepam; Half-Life; Humans; Kinetics; Lorazepam | 1982 |
Pharmacokinetics and biotransformation of the new benzodiazepine, lormetazepam, in man. III. Repeated administration and transfer to neonates via breast milk.
Topics: Anti-Anxiety Agents; Benzodiazepines; Biotransformation; Female; Humans; Infant, Newborn; Lorazepam; Milk, Human | 1983 |
Hypnotic activity of lormetazepam and camazepam.
Topics: Anti-Anxiety Agents; Benzodiazepines; Humans; Hypnotics and Sedatives; Lorazepam; Male; Research Design; Temazepam | 1983 |
The alpha-sleep pattern. Differentiation from other sleep patterns and effect of hypnotics.
Topics: Adult; Aged; Alpha Rhythm; Anti-Anxiety Agents; Benzodiazepines; Electroencephalography; Female; Flurazepam; Humans; Lorazepam; Male; Middle Aged; Sleep Stages; Sleep, REM; Theta Rhythm | 1983 |
Alcohol interaction of lormetazepam, mepindolol sulphate and diazepam measured by performance on the driving simulator.
Topics: Adult; Anti-Anxiety Agents; Automobile Driving; Benzodiazepines; Diazepam; Double-Blind Method; Drug Interactions; Ethanol; Female; Humans; Lorazepam; Male; Pindolol; Placebos; Psychomotor Performance; Pulse; Reaction Time | 1984 |
[Our electroencephalographic data in the framework of a review on lormetazepam].
Topics: Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Electroencephalography; Female; Humans; Lorazepam; Male; Middle Aged; Placebos; Sleep Initiation and Maintenance Disorders; Triazolam | 1984 |
Pharmacodynamic correlates of modified absorption: studies with lormetazepam.
Topics: Absorption; Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Biological Availability; Capsules; Humans; Kinetics; Lorazepam; Male; Middle Aged; Tablets | 1984 |
The effects of benzodiazepines on short-term memory and information processing.
Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Female; Flunitrazepam; Humans; Lorazepam; Memory, Short-Term; Models, Psychological; Reaction Time; Triazolam | 1984 |
Simulated car driving as a useful technique for the determination of residual effects and alcohol interaction after short- and long-acting benzodiazepines.
Topics: Anti-Anxiety Agents; Automobile Driving; Benzodiazepines; Diazepam; Double-Blind Method; Drug Interactions; Ethanol; Flurazepam; Heart Rate; Humans; Hypnotics and Sedatives; Lorazepam; Pindolol; Psychomotor Performance; Reaction Time | 1984 |
Lormetazepam--plasma concentrations in volunteers following sublingual and oral dosing.
Topics: Administration, Oral; Anti-Anxiety Agents; Benzodiazepines; Humans; Hypnotics and Sedatives; Intestinal Absorption; Kinetics; Lorazepam; Male; Tablets | 1984 |
Histamine release in anaesthesia and surgery. premedication with H1- and H2-receptor antagonists: indications, benefits and possible problems.
Topics: Adjuvants, Anesthesia; Anaphylaxis; Anesthetics; Anti-Anxiety Agents; Benzodiazepines; Drug Combinations; Etomidate; Glucocorticoids; Histamine Antagonists; Histamine Release; Humans; Lorazepam; Neuromuscular Blocking Agents; Premedication | 1982 |
[Benzodiazepines: effects on sleep and on attention capacity the following day. Long-term study administration of lormetazepam and flurazepam].
Topics: Adult; Anti-Anxiety Agents; Attention; Benzodiazepines; Female; Flurazepam; Humans; Lorazepam; Male; Middle Aged; Sleep; Sleep Initiation and Maintenance Disorders | 1984 |
[Lormetazepam].
Topics: Anti-Anxiety Agents; Benzodiazepines; Drug Interactions; Humans; Kinetics; Lorazepam; Sleep Initiation and Maintenance Disorders | 1984 |
Effects of bicuculline and lormetazepam on conditioning avoidance in the rat.
Topics: Animals; Anti-Anxiety Agents; Avoidance Learning; Benzodiazepines; Bicuculline; Electroshock; gamma-Aminobutyric Acid; Lorazepam; Male; Rats; Rats, Inbred Strains; Time Factors | 1983 |
[Ataractic treatment in psychiatry and general medicine. Review of preparations. 9].
Topics: Adjustment Disorders; Anthracenes; Anti-Anxiety Agents; Benzodiazepines; Humans; Lorazepam; Maprotiline; Medazepam; Neurotic Disorders; Psychophysiologic Disorders; Psychotic Disorders; Sleep Wake Disorders; Tranquilizing Agents | 1983 |
Driving ability following the subchronic application of lormetazepam, flurazepam and placebo.
Topics: Adult; Anti-Anxiety Agents; Automobile Driving; Benzodiazepines; Double-Blind Method; Female; Flurazepam; Humans; Lorazepam; Male; Reaction Time | 1983 |
[Hemodynamic changes following the injection of lormetazepam under premedication and anesthesia conditions in coronary surgery patients].
Topics: Anesthesia, General; Anti-Anxiety Agents; Benzodiazepines; Cardiac Surgical Procedures; Extracorporeal Circulation; Heart Rate; Hemodynamics; Humans; Hydrogen-Ion Concentration; Lorazepam; Preanesthetic Medication | 1983 |
Effects of lormetazepam and of flurazepam on sleep.
Topics: Aged; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Female; Flurazepam; Half-Life; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Sleep; Sleep Wake Disorders; Substance Withdrawal Syndrome; Time Factors | 1984 |
Benzodiazepine administration induces exogenic psychosis: a case of child abuse.
Topics: Aggression; Anti-Anxiety Agents; Benzodiazepines; Child; Child Abuse; Child Welfare; Humans; Lorazepam; Male; Munchausen Syndrome by Proxy; Psychoses, Substance-Induced | 1995 |
Suppression of chiral recognition of 3-hydroxy-1,4-benzodiazepines during micellar electrokinetic capillary chromatography with bile salts.
Topics: Anti-Anxiety Agents; Benzodiazepines; Bile Acids and Salts; Capillary Action; Chromatography; Kinetics; Lorazepam; Micelles; Oxazepam; Temazepam | 1995 |
Acute exogenic psychosis following oral ingestion of 2 mg lormetazepam in an eleven-year-old boy.
Topics: Adolescent; Animals; Anti-Anxiety Agents; Benzodiazepines; Child; Electroencephalography; Guinea Pigs; Humans; Lorazepam; Male; Psychoses, Substance-Induced | 1993 |
[Detection of lorazepam and lormetazepam metabolites in urine using thin-layer chromatography].
Topics: Anti-Anxiety Agents; Benzodiazepines; Benzophenones; Chromatography, Thin Layer; Humans; Lorazepam | 1998 |
Comparison of different immunoassays and GC-MS screening of benzodiazepines in urine.
Topics: Anti-Anxiety Agents; Benzodiazepines; Gas Chromatography-Mass Spectrometry; Humans; Immunoassay; Lorazepam; Reproducibility of Results; Sensitivity and Specificity | 1998 |
Sexual assault under benzodiazepine submission in a Paris suburb.
Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Cocaine; Dronabinol; Estazolam; Female; Flunitrazepam; Humans; Hypnotics and Sedatives; Immunoassay; Lorazepam; Male; Morphine; Narcotics; Nitrazepam; Paris; Rape; Retrospective Studies; Substance-Related Disorders; Temazepam; Time Factors; Triazolam | 2000 |
Successful prolonged cardiopulmonary resuscitation after a combined intoxication with a tricyclic antidepressant, a benzodiazepine and a neuroleptic.
Topics: Adult; Alprazolam; Amitriptyline; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Benzodiazepines; Cardiopulmonary Resuscitation; Emergencies; Female; Humans; Lorazepam; Suicide, Attempted; Thiazines; Time Factors | 2000 |
[Instead of benzodiazepines. An antidepressant as sleep aid].
Topics: Anti-Anxiety Agents; Antidepressive Agents; Benzodiazepines; Chronic Disease; Clinical Trials as Topic; Humans; Lorazepam; Sleep Initiation and Maintenance Disorders; Trimipramine | 2001 |
Determination of lormetazepam and its main metabolite in serum using micellar electrokinetic capillary chromatography with direct injection and ultraviolet absorbance detection.
Topics: Anti-Anxiety Agents; Benzodiazepines; Buffers; Chromatography, Micellar Electrokinetic Capillary; Humans; Hydrogen-Ion Concentration; Lorazepam; Sensitivity and Specificity; Surface-Active Agents | 2002 |
Musical hallucinations during a treatment with benzodiazepine.
Topics: Amitriptyline; Anti-Anxiety Agents; Anxiety Disorders; Benzodiazepines; Depressive Disorder; Dose-Response Relationship, Drug; Drug Therapy, Combination; Female; Hallucinations; Humans; Lorazepam; Middle Aged; Music; Tinnitus | 2002 |
Effects of short-acting hypnotics on sleep latency in rats placed on grid suspended over water.
Topics: Animals; Anti-Anxiety Agents; Azabicyclo Compounds; Azepines; Benzodiazepines; Dose-Response Relationship, Drug; Electroencephalography; Electromyography; Hypnotics and Sedatives; Lorazepam; Male; Piperazines; Rats; Rats, Wistar; Sleep; Time Factors; Triazolam; Water | 2003 |
Quantification of lorazepam and lormetazepam in human breast milk using GC-MS in the negative chemical ionization mode.
Topics: Adult; Female; Gas Chromatography-Mass Spectrometry; Humans; Hypnotics and Sedatives; Lorazepam; Milk, Human; Reproducibility of Results | 2007 |
Evaluation of anxiolytic-like effects of some short-acting benzodiazepine hypnotics in mice.
Topics: Animals; Anti-Anxiety Agents; Anxiety; Azepines; Benzodiazepines; Diazepam; Hypnotics and Sedatives; Lorazepam; Male; Maze Learning; Mice; Mice, Inbred ICR; Motor Activity; Triazolam | 2008 |
[Paroxetine-induced severe hyponatremic rhabdomyolisis].
Topics: Cations; Coma; Depressive Disorder; Diagnosis, Differential; Epilepsy, Tonic-Clonic; Female; Humans; Hyponatremia; Lorazepam; Middle Aged; Muscle Cells; Paroxetine; Rhabdomyolysis; Saline Solution, Hypertonic; Selective Serotonin Reuptake Inhibitors | 2008 |
[Possible malignant neuroleptic syndrome associated with aripiprazole and imipramine and treated with bromocriptine].
Topics: Antipsychotic Agents; Aripiprazole; Bromocriptine; Combined Modality Therapy; Drug Therapy, Combination; Emergencies; Frontotemporal Dementia; Humans; Imipramine; Lorazepam; Male; Mental Disorders; Middle Aged; Neuroleptic Malignant Syndrome; Oxygen Inhalation Therapy; Piperazines; Quinolones; Respiration, Artificial; Respiratory Insufficiency | 2013 |
Neuropsychiatric features in Behçet's disease: a case report.
Topics: Adult; Antipsychotic Agents; Behcet Syndrome; Bipolar Disorder; Brain; Butyrophenones; Diagnostic and Statistical Manual of Mental Disorders; Heterozygote; HLA-B51 Antigen; Humans; Hypnotics and Sedatives; Lorazepam; Male; Skin Tests; Suicidal Ideation; Tomography, X-Ray Computed | 2014 |
Chemometric approach to open validation protocols: Prediction of validation parameters in multi-residue ultra-high performance liquid chromatography-tandem mass spectrometry methods.
Topics: Chromatography, High Pressure Liquid; Humans; Hypnotics and Sedatives; Illicit Drugs; Least-Squares Analysis; Limit of Detection; Lorazepam; Naloxone; Narcotic Antagonists; Tandem Mass Spectrometry; Validation Studies as Topic | 2015 |
Socio-demographic and clinical characteristics of benzodiazepine long-term users: Results from a tertiary care center.
Topics: Adult; Anxiety Disorders; Benzodiazepines; Dose-Response Relationship, Drug; Female; Humans; Long-Term Care; Lorazepam; Male; Middle Aged; Sleep Initiation and Maintenance Disorders; Substance-Related Disorders; Tertiary Care Centers | 2016 |
Characterization and identification of eight designer benzodiazepine metabolites by incubation with human liver microsomes and analysis by a triple quadrupole mass spectrometer.
Topics: Adult; Benzodiazepines; Chromatography, Liquid; Designer Drugs; Humans; Lorazepam; Male; Microsomes, Liver; Oxazepam; Substance-Related Disorders; Tandem Mass Spectrometry | 2017 |
Double false result in a drug screen after accidental pediatric poisoning.
Topics: Antidepressive Agents, Tricyclic; Chromatography, High Pressure Liquid; Emergencies; False Negative Reactions; Female; Gas Chromatography-Mass Spectrometry; Glucuronides; Humans; Hydrolysis; Immunoassay; Inactivation, Metabolic; Infant; Lorazepam; Quetiapine Fumarate | 2018 |
A risk for athletes: when the desire to sleep becomes a nightmare. A brief case report on benzodiazepine addiction.
Topics: Adult; Athletes; Behavior, Addictive; Benzodiazepines; Bicycling; Dreams; Humans; Hypnotics and Sedatives; Lorazepam; Male; Polysomnography; Risk Factors; Sleep | 2018 |
High-dose lormetazepam dependence: strange case of Dr. Jekyll and Mr. Hyde.
Topics: Adult; Benzodiazepines; Female; Humans; Italy; Lorazepam; Male; Middle Aged; Prevalence; Retrospective Studies; Substance-Related Disorders | 2019 |
Lormetazepam in oral solution: a formulation at risk of high-dose use.
Topics: Benzodiazepines; Humans; Lorazepam | 2019 |
High-dose lormetazepam dependence: strange case of Dr. Jekyll and Mr. Hyde-comment.
Topics: Humans; Lorazepam | 2020 |
Benzodiazepine abuse among athletes: Pain relief or just a weapon against insomnia? A clinical case study.
Topics: Adult; Athletes; Female; Humans; Lorazepam; Pain; Pain Management; Sleep; Sleep Initiation and Maintenance Disorders; Substance-Related Disorders | 2019 |
High-dose lormetazepam dependence: strange case of Dr. Jekyll and Mr. Hyde-reply.
Topics: Humans; Lorazepam | 2020 |
Organ distribution of diclazepam, pyrazolam and 3-fluorophenmetrazine.
Topics: Adult; Benzodiazepines; Bile; Body Fluids; Brain Chemistry; Designer Drugs; Diazepam; Forensic Toxicology; Gastrointestinal Contents; Humans; Kidney; Liver; Lorazepam; Lung; Male; Nordazepam; Pericardial Fluid; Phenmetrazine; Postmortem Changes; Psoas Muscles; Tandem Mass Spectrometry | 2019 |
Postmortem Analysis of Benzodiazepines in Human Bone by Gas Chromatography-Mass Spectrometry.
Topics: Alprazolam; Autopsy; Benzodiazepines; Chromatography, Liquid; Clonazepam; Diazepam; Forensic Toxicology; Gas Chromatography-Mass Spectrometry; Humans; Liquid-Liquid Extraction; Lorazepam; Nordazepam; Oxazepam; Tandem Mass Spectrometry | 2021 |
Can oral formulation increase the risk of lormetazepam abuse?
Topics: Administration, Oral; Ethanol; Humans; Hypnotics and Sedatives; Lorazepam; Risk Factors; Substance-Related Disorders | 2021 |
Clearance of Lormetazepam, Midazolam, and Their Conjugated Metabolites by Continuous Venovenous Hemofiltration During Prolonged Sedation in Critically Ill Patients With COVID-19-Associated Acute Respiratory Distress Syndrome.
Topics: Aged; Continuous Renal Replacement Therapy; COVID-19; COVID-19 Drug Treatment; Critical Illness; Deep Sedation; Humans; Hypnotics and Sedatives; Lorazepam; Male; Midazolam; Middle Aged; Respiratory Distress Syndrome | 2022 |