lorazepam and flunitrazepam

lorazepam has been researched along with flunitrazepam in 70 studies

Research

Studies (70)

Timeframe	Studies, this research(%)	All Research%
pre-1990	43 (61.43)	18.7374
1990's	14 (20.00)	18.2507
2000's	9 (12.86)	29.6817
2010's	4 (5.71)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Johnston, GA; Maddalena, DJ	1
Karplus, M; So, SS	1
Topliss, JG; Yoshida, F	1
Chang, TK; Ensom, MH; Kiang, TK	1
Lombardo, F; Obach, RS; Waters, NJ	1
Alelyunas, YW; Bui, K; Empfield, JR; McCarthy, D; Pelosi-Kilby, L; Shen, C; Spreen, RC	1
Dundee, JW; George, KA	2
Dundee, JW; Hegarty, JE	1
Heipertz, W; Junger, H; Schorer, R; Vontin, H	1
Arfel, G; Berger, G; Comar, D; Godot, JM; Maziere, M; Menini, C; Naquet, R; Soussaline, F	1
Bailey, J; Glue, P; Hudson, A; Nutt, DJ; Wilson, S	1
Allan, AM; Baier, LD; Zhang, X	1
Beck, O; Borg, S; Hjemdahl, P; Lafolie, P; Odelius, G; Wirbing, P	1
Daubländer, M; Lipp, M	1
Doenicke, A; Greim, M; Juhl, G; Rampf, U; Suttmann, H	1
Betschart, J; Blanchard, JC; Piot, O; Stutzmann, JM	1
Greenblatt, DJ; Miller, LG; Roy, RB; Shader, RI; Summer, WR	1
Lopez, F; Miller, LG; Roy, RB; Weill, CL	1
Klotz, U	1
Hellevuo, K; Korpi, ER	1
Gaver, A; Miller, LG; Roy, RB; Weill, CL	1
Peroutka, SJ	1
Kubicki, S; Meyer, C; Röhmel, J	1
Bénézech, M; Rager, P	1
Ackenheil, M; Doenicke, A; Dorow, R; Duka, T; Noderer, J	1
Barattini, M; Fantozzi, R; Mannaioni, PF; Masini, E	1
Aufdembrinke, B; Fichte, K; Ott, H; Rohloff, A	1
Aaltonen, L; Aantaa, E; Kanto, J; Salonen, M	1
Fioretti, P; Galbani, P; Gambacciani, M; Melis, GB; Ronca-Testoni, S	1
Haag-Wüsthof, C; Herrmann, WM; Kubicki, S; Röhmel, J; Scheuler, W	1
Fogh, B; Rasmussen, K	1
Eichinger, V; Heipertz, W; Hempel, V; Vontin, H	1
Evans, WE; Riley, CA	1
Doenicke, A; Dorow, R; Duka, T; Klotz, U	1
de Thier, D; Machowsky, R; Mantanus, H; Rousseau, JC; Timsit-Berthier, M	1
Fioretti, P; Galbani, P; Gambacciani, M; Melis, G; Ronca-Testoni, S	1
Gibbs, JM; Lim, YT; Male, CG; Male, M; Stewart, JM	1
Clarke, RS; Dundee, JW; Howard, PJ; McGowan, WA	1
Kangas, L; Kanto, J; Mansikka, M	1
Dudkiewicz, J; Misterek, K	1
Fernández Labriola, R; Fichte, K; Satre y Hernández, M	1
Cepeda, C; Comar, D; Godot, JM; Maziere, M; Menini, C; Naquet, R	1
Fichte, K; Sastre-y-Hernández, M; Studer, A	1
Kanto, JH	1
Fasching, I; Haubenstock, A; Hruby, K; Jäger, U	1
Breimer, DD; Jochemsen, R	1
Olive, G; Rey, E	1
Ott, H	1
Subhan, Z	1
Hindmarch, I; Subhan, Z	1
Cepeda, C; Comar, D; Crouzel, M; Guibert, B; Hantraye, P; Kaijima, M; Maziere, M; Naquet, R; Prenant, C; Sastre, J	1
Doenicke, A	1
Fitzal, S; Groll-Knapp, E; Länger, W; Riegler, R	1
Aaltonen, L; Scheinin, M	1
Bouvy, PF; Duivenvoorden, HJ; Haffmans, PM; Nolen, WA	1
de Iceta, M; Martínez-Cano, H; Martínez-Gras, I; Pomalima, R; Vela-Bueno, A	1
Bouvy, PF; de Groot, MH; Huijsman, AM; Nolen, WA	1
Mersch, F; Wennig, R; Yegles, M	1
Barnes, EM; Tehrani, MH	1
Bechgaard, E; Gizurarson, S; Greenough, RJ; Hjortkjaer, RK; McDonald, P; Suzdak, C	1
Angelopoulos, EK; Chioni, A; Daskalopoulou, EG; Gatzonis, SD; Mantouvalos, V; Siafakas, A; Zournas, C	1
Baudry, F; Douceron, H; Hassnaoui, S; Marc, B; Vaquero, P; Zerrouki, L	1
Bueno, OF; Galduróz, JC; Lucchesi, LM; Manzano, GM; Pompéia, S; Tufik, S	1
Bueno, OF; Galduróz, JC; Manzano, GM; Pompéia, S; Tufik, S	1
Bueno, OF; Galduróz, JC; Pompéia, S; Tufik, S	1
Fahey, JM; Grassi, JM; Greenblatt, DJ; Reddi, JM	1
Gunn, J; Kriger, S; Terrell, AR	1
Chèze, M; Deveaux, M; Hoizey, G; Muckensturm, A; Pépin, G	1
Alt-Epping, B; Nauck, F; Radbruch, L; Sitte, T	1

Reviews

6 review(s) available for lorazepam and flunitrazepam

Article	Year
UDP-glucuronosyltransferases and clinical drug-drug interactions. Pharmacology & therapeutics, 2005, Volume: 106, Issue:1 Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic	2005
[Current intravenous anesthetics]. Polski tygodnik lekarski (Warsaw, Poland : 1960), 1980, Volume: 35, Issue:43 Topics: Anesthesia, Intravenous; Anesthetics; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Etomidate; Flunitrazepam; Imidazoles; Injections, Intravenous; Lorazepam; Medazepam; Midazolam; Nordazepam	1980
Use of benzodiazepines during pregnancy, labour and lactation, with particular reference to pharmacokinetic considerations. Drugs, 1982, Volume: 23, Issue:5 Topics: Anti-Anxiety Agents; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female; Flunitrazepam; Humans; Infant, Newborn; Labor, Obstetric; Lactation; Lorazepam; Maternal-Fetal Exchange; Nitrazepam; Oxazepam; Pregnancy	1982
[Benzodiazepines and pregnancy. Transplacental passage, labor and lactation]. L'Encephale, 1983, Volume: 9, Issue:4 Suppl 2 Topics: Anti-Anxiety Agents; Biotransformation; Chlordiazepoxide; Clorazepate Dipotassium; Diazepam; Female; Flunitrazepam; Humans; Kinetics; Lorazepam; Maternal-Fetal Exchange; Milk, Human; Nitrazepam; Oxazepam; Postpartum Period; Pregnancy	1983
Modern trends in the investigation of new hypnotics in anaesthesia. Psychopharmacology. Supplementum, 1984, Volume: 1 Topics: Anesthesia; Anti-Anxiety Agents; Arousal; Benzodiazepines; Electroencephalography; Electrophysiology; Flunitrazepam; Half-Life; Humans; Hypnotics and Sedatives; Lorazepam; Midazolam; Psychometrics	1984
[Sedation in palliative medicine: Guidelines for the use of sedation in palliative care : European Association for Palliative Care (EAPC)]. Schmerz (Berlin, Germany), 2010, Volume: 24, Issue:4 Topics: Antipsychotic Agents; Conscious Sedation; Europe; Flunitrazepam; Health Services Misuse; Humans; Lorazepam; Palliative Care; Practice Guidelines as Topic; Risk Assessment; Societies, Medical	2010

Trials

25 trial(s) available for lorazepam and flunitrazepam

Article	Year
Relative amnesic actions of diazepam, flunitrazepam and lorazepam in man. British journal of clinical pharmacology, 1977, Volume: 4, Issue:1 Topics: Amnesia; Anesthesia; Anti-Anxiety Agents; Diazepam; Female; Flunitrazepam; Humans; Lorazepam; Time Factors	1977
Sequelae after the intravenous injection of three benzodiazepines--diazepam, lorazepam, and flunitrazepam. British medical journal, 1977, Nov-26, Volume: 2, Issue:6099 Topics: Anti-Anxiety Agents; Diazepam; Flunitrazepam; Humans; Injections, Intravenous; Lorazepam; Phlebitis; Thrombophlebitis	1977
Thyrotropin-releasing hormone selectively reverses lorazepam-induced sedation but not slowing of saccadic eye movements. Life sciences, 1992, Volume: 50, Issue:6 Topics: Adult; Conscious Sedation; Female; Flumazenil; Flunitrazepam; Humans; Injections, Intravenous; Kinetics; Lorazepam; Male; Radioligand Assay; Receptors, GABA-A; Saccades; Sleep Stages; Thyrotropin-Releasing Hormone	1992
[Beta activation following the intravenous administration of benzodiazepines and the specific antagonist flumazenil (Ro 15-1788)]. EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete, 1990, Volume: 21, Issue:1 Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Beta Rhythm; Diazepam; Dose-Response Relationship, Drug; Electroencephalography; Flumazenil; Flunitrazepam; Humans; Injections, Intravenous; Lorazepam; Male; Midazolam; Prospective Studies; Randomized Controlled Trials as Topic; Stimulation, Chemical	1990
[The 4 second sleep spindle periodicity]. EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete, 1986, Volume: 17, Issue:2 Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Cerebral Cortex; Double-Blind Method; Electroencephalography; Evoked Potentials; Flunitrazepam; Humans; Lorazepam; Methaqualone; Middle Aged; Pentobarbital; Periodicity; Random Allocation; Sleep Stages; Triazolam; Urea	1986
Changes in noradrenaline plasma levels and behavioural responses induced by benzodiazepine agonists with the benzodiazepine antagonist Ro 15-1788. Psychopharmacology, 1986, Volume: 90, Issue:3 Topics: Adult; Animals; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Blood Pressure; Double-Blind Method; Electrocardiography; Electroencephalography; Flumazenil; Flunitrazepam; Humans; Lorazepam; Male; Norepinephrine; Random Allocation	1986
Anterograde and retrograde amnesia after lormetazepam and flunitrazepam. Psychopharmacology series, 1988, Volume: 6 Topics: Amnesia; Amnesia, Retrograde; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Emotions; Flunitrazepam; Humans; Lorazepam; Male; Memory; Psychomotor Performance; Time Factors	1988
Saccadic eye movements in determination of the residual effects of the benzodiazepines. International journal of clinical pharmacology, therapy, and toxicology, 1986, Volume: 24, Issue:5 Topics: Benzodiazepines; Eye Movements; Flunitrazepam; Humans; Hypnotics and Sedatives; Lorazepam; Midazolam; Placebos; Saccades; Sleep; Time Factors	1986
[Sublingual administration of flunitrazepam (Rohypnol) and lorazepam (Temesta) for premedication. A randomized double-blind study]. Ugeskrift for laeger, 1988, May-30, Volume: 150, Issue:22 Topics: Administration, Sublingual; Clinical Trials as Topic; Double-Blind Method; Female; Flunitrazepam; Humans; Lorazepam; Preanesthetic Medication; Random Allocation	1988
[Plasma concentration and amnesia following lormetazepam and flunitrazepam in i.v. premedication]. Anasthesie, Intensivtherapie, Notfallmedizin, 1986, Volume: 21, Issue:3 Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Female; Flunitrazepam; Humans; Infusions, Parenteral; Kinetics; Lorazepam; Male; Memory; Mental Recall; Middle Aged; Pattern Recognition, Visual; Preanesthetic Medication; Random Allocation; Retention, Psychology	1986
Flunitrazepam and lormetazepam do not affect the pharmacokinetics of the benzodiazepine antagonist Ro 15-1788. British journal of clinical pharmacology, 1985, Volume: 19, Issue:1 Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Flumazenil; Flunitrazepam; Humans; Kinetics; Lorazepam; Male	1985
Sleep and wake after benzodiazepine hypnotics: a 20-hour EEG comparison of lormetazepam and flunitrazepam. Current medical research and opinion, 1985, Volume: 9, Issue:8 Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Electroencephalography; Female; Flunitrazepam; Half-Life; Humans; Hypnotics and Sedatives; Kinetics; Lorazepam; Male; Random Allocation; Sleep; Sleep Stages; Spectrum Analysis; Time Factors; Wakefulness	1985
Comparison of three benzodiazepines for oral premedication in minor gynaecological surgery. British journal of anaesthesia, 1980, Volume: 52, Issue:4 Topics: Adolescent; Adult; Anti-Anxiety Agents; Anxiety; Clinical Trials as Topic; Diazepam; Dilatation and Curettage; Double-Blind Method; Female; Flunitrazepam; Humans; Lorazepam; Mental Recall; Middle Aged; Personality Inventory; Placebos; Preanesthetic Medication; Random Allocation	1980
Comparison of the subjective effects and plasma concentrations following oral and i.m. administration of flunitrazepam in patients. British journal of anaesthesia, 1980, Volume: 52, Issue:4 Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Clinical Trials as Topic; Diazepam; Double-Blind Method; Female; Flunitrazepam; Humans; Injections, Intramuscular; Lorazepam; Pain; Preanesthetic Medication; Random Allocation; Time Factors	1980
A comparative study on the clinical effects of flunitrazepam and lorazepam. International journal of clinical pharmacology, therapy, and toxicology, 1980, Volume: 18, Issue:7 Topics: Adult; Anti-Anxiety Agents; Blood Pressure; Clinical Trials as Topic; Double-Blind Method; Emotions; Female; Flunitrazepam; Heart Rate; Humans; Lorazepam; Preoperative Care	1980
[Comparison of lormetazepam, flunitrazepam and placebo in a long-term effect and long-term tolerance study in 105 patients with chronic sleep disorders]. ZFA. Zeitschrift fur Allgemeinmedizin, 1981, Aug-31, Volume: 57, Issue:24 Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Drug Tolerance; Female; Flunitrazepam; Humans; Lorazepam; Male; Middle Aged; Placebos; Sleep Wake Disorders	1981
[Comparison of lormetazepam and flunitrazepam in general practice (author's transl)]. Schweizerische Rundschau fur Medizin Praxis = Revue suisse de medecine Praxis, 1982, Mar-09, Volume: 71, Issue:10 Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Clinical Trials as Topic; Double-Blind Method; Female; Flunitrazepam; Humans; Lorazepam; Male; Middle Aged; Random Allocation; Sleep Initiation and Maintenance Disorders	1982
Are electroencephalographic and psychomotor measures sensitive in detecting residual sequelae of benzodiazepine hypnotics? Psychopharmacology. Supplementum, 1984, Volume: 1 Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Diazepam; Double-Blind Method; Electroencephalography; Female; Flunitrazepam; Half-Life; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Psychomotor Performance; Radioligand Assay; Sleep	1984
Effects of zopiclone and benzodiazepine hypnotics on search in short-term memory. Neuropsychobiology, 1984, Volume: 12, Issue:4 Topics: Adult; Anti-Anxiety Agents; Azabicyclo Compounds; Benzodiazepines; Female; Flunitrazepam; Humans; Lorazepam; Memory, Short-Term; Piperazines; Reaction Time; Triazolam	1984
[Premedication with flunitrazepam, lormetazepam or pethidine-promethazine. Psychometric study of subjective conditions]. Der Anaesthesist, 1983, Volume: 32, Issue:6 Topics: Adult; Amnesia; Anti-Anxiety Agents; Anxiety; Benzodiazepines; Depression; Emotions; Flunitrazepam; Humans; Hypnotics and Sedatives; Lorazepam; Meperidine; Middle Aged; Preoperative Care; Promethazine; Psychometrics	1983
Hypnotics as concurrent medication in depression. A placebo-controlled, double-blind comparison of flunitrazepam and lormetazepam in patients with major depression, treated with a (tri)cyclic antidepressant. Journal of affective disorders, 1993, Volume: 28, Issue:3 Topics: Adult; Anti-Anxiety Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Depressive Disorder; Double-Blind Method; Drug Therapy, Combination; Female; Flunitrazepam; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Placebos; Plasma; Severity of Illness Index; Sleep Wake Disorders; Sleep, REM	1993
Lateralized neuropsychological functioning in depressive patients before and after drug therapy. Biological psychiatry, 1996, Dec-15, Volume: 40, Issue:12 Topics: Adult; Aged; Anti-Anxiety Agents; Antidepressive Agents; Antidepressive Agents, Tricyclic; Benzodiazepines; Cognition; Depressive Disorder; Female; Flunitrazepam; Functional Laterality; Humans; Lorazepam; Male; Middle Aged; Neuropsychological Tests; Psychiatric Status Rating Scales	1996
A double-dissociation of behavioural and event-related potential effects of two benzodiazepines with similar potencies. Journal of psychopharmacology (Oxford, England), 2000, Volume: 14, Issue:3 Topics: Adolescent; Adult; Analysis of Variance; Anti-Anxiety Agents; Double-Blind Method; Dronabinol; Evoked Potentials; Evoked Potentials, Auditory; Female; Flunitrazepam; Humans; Lorazepam; Male; Memory, Short-Term; Perception; Photic Stimulation; Placebos; Psychomotor Performance; Reaction Time; Reference Values	2000
Lorazepam induces an atypical dissociation of visual and auditory event-related potentials. Journal of psychopharmacology (Oxford, England), 2003, Volume: 17, Issue:1 Topics: Adolescent; Adult; Analysis of Variance; Anti-Anxiety Agents; Cognition; Double-Blind Method; Evoked Potentials, Auditory; Evoked Potentials, Visual; Female; Flunitrazepam; Humans; Lorazepam; Male; Psychomotor Performance; Time Factors	2003
Stem-completion tasks (indirect, direct inclusion and exclusion) are differently affected by equipotent doses of lorazepam and flunitrazepam. Human psychopharmacology, 2003, Volume: 18, Issue:7 Topics: Administration, Oral; Adolescent; Adult; Anti-Anxiety Agents; Double-Blind Method; Female; Flunitrazepam; Humans; Lorazepam; Male; Memory; Mental Recall; Psychological Tests	2003

Other Studies

39 other study(ies) available for lorazepam and flunitrazepam

Article	Year
Prediction of receptor properties and binding affinity of ligands to benzodiazepine/GABAA receptors using artificial neural networks. Journal of medicinal chemistry, 1995, Feb-17, Volume: 38, Issue:4 Topics: Binding Sites; Ligands; Neural Networks, Computer; Predictive Value of Tests; Receptors, GABA-A; Structure-Activity Relationship	1995
Genetic neural networks for quantitative structure-activity relationships: improvements and application of benzodiazepine affinity for benzodiazepine/GABAA receptors. Journal of medicinal chemistry, 1996, Dec-20, Volume: 39, Issue:26 Topics: Algorithms; Benzodiazepines; Models, Genetic; Nerve Net; Protein Binding; Receptors, GABA-A; Structure-Activity Relationship	1996
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
Experimental solubility profiling of marketed CNS drugs, exploring solubility limit of CNS discovery candidate. Bioorganic & medicinal chemistry letters, 2010, Dec-15, Volume: 20, Issue:24 Topics: Central Nervous System Agents; Drug Evaluation, Preclinical; Hydrogen-Ion Concentration; Pharmaceutical Preparations; Solubility	2010
The amnesic action of diazepam, flunitrazepam and lorazepam in man. Acta anaesthesiologica Belgica, 1976, Volume: 27 suppl Topics: Amnesia; Anti-Anxiety Agents; Diazepam; Dose-Response Relationship, Drug; Female; Flunitrazepam; Humans; Lorazepam; Time Factors	1976
[Amnesia after the benzodiazepines flunitrazepam and lorazepam]. Klinische Anasthesiologie und Intensivtherapie, 1978, Issue:17 Topics: Amnesia; Anti-Anxiety Agents; Flunitrazepam; Humans; Lorazepam; Time Factors	1978
Visualisation of 11C-flunitrazepam displacement in the brain of the live baboon. Nature, 1979, Jul-26, Volume: 280, Issue:5720 Topics: Animals; Anti-Anxiety Agents; Brain; Carbon Radioisotopes; Female; Flunitrazepam; Haplorhini; Lorazepam; Papio; Radionuclide Imaging	1979
Effects of lorazepam tolerance and withdrawal on GABAA receptor-operated chloride channels. The Journal of pharmacology and experimental therapeutics, 1992, Volume: 261, Issue:2 Topics: Animals; Appetite Depressants; Binding Sites; Brain; Carbolines; Chloride Channels; Chlorides; Diazepam; Drug Interactions; Ethanol; Flunitrazepam; Ion Channels; Lorazepam; Male; Membrane Proteins; Mice; Mice, Inbred ICR; Phenobarbital; Receptors, GABA-A	1992
Detection of benzodiazepine intake in therapeutic doses by immunoanalysis of urine: two techniques evaluated and modified for improved performance. Clinical chemistry, 1992, Volume: 38, Issue:2 Topics: Adult; Alprazolam; Benzodiazepines; Chlordiazepoxide; False Negative Reactions; Flunitrazepam; Fluorescence Polarization Immunoassay; Humans; Immunoenzyme Techniques; Lorazepam; Male; Middle Aged; Nitrazepam; Triazolam	1992
[Premedication and analgesic dose procedures in dental medicine]. Zahnarztliche Praxis, 1991, Jul-12, Volume: 42, Issue:7 Topics: Anesthesia, Dental; Anesthesia, Local; Buprenorphine; Clorazepate Dipotassium; Diazepam; Flunitrazepam; Humans; Lorazepam; Meperidine; Midazolam; Morphine; Oxazepam; Pain; Pentazocine; Pirinitramide; Preanesthetic Medication	1991
Cyclopyrrolones, unlike some benzodiazepines, do not induce physical dependence in mice. Neuroscience letters, 1990, Sep-04, Volume: 117, Issue:1-2 Topics: Animals; Azabicyclo Compounds; Carbolines; Convulsants; Diazepam; Disease Models, Animal; Flunitrazepam; Hypnotics and Sedatives; Lorazepam; Male; Mice; Mice, Inbred Strains; Naphthyridines; Piperazines; Seizures; Structure-Activity Relationship; Substance-Related Disorders; Sulfur Compounds; Triazolam	1990
Chronic benzodiazepine administration. II. Discontinuation syndrome is associated with upregulation of gamma-aminobutyric acidA receptor complex binding and function. The Journal of pharmacology and experimental therapeutics, 1988, Volume: 246, Issue:1 Topics: Animals; Binding Sites; Brain; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chlorides; Drug Tolerance; Flumazenil; Flunitrazepam; Ion Channels; Lorazepam; Male; Mice; Motor Activity; Muscimol; Receptors, GABA-A; Time Factors	1988
Persistent alterations in GABAA receptor binding and function after prenatal lorazepam administration in the chick. Brain research bulletin, 1989, Volume: 23, Issue:3 Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Chick Embryo; Chickens; Chlorides; Female; Flunitrazepam; Lorazepam; Muscimol; Pregnancy; Prenatal Exposure Delayed Effects; Radioligand Assay; Receptors, GABA-A	1989
Drug interactions and clinical pharmacokinetics of flumazenil. European journal of anaesthesiology. Supplement, 1988, Volume: 2 Topics: Anti-Anxiety Agents; Benzodiazepines; Biological Availability; Drug Interactions; Ethanol; Flumazenil; Flunitrazepam; Half-Life; Humans; Liver; Lorazepam; Midazolam; Receptors, GABA-A; Tomography, Emission-Computed	1988
Failure of Ro 15-4513 to antagonize ethanol in rat lines selected for differential sensitivity to ethanol and in Wistar rats. Pharmacology, biochemistry, and behavior, 1988, Volume: 30, Issue:1 Topics: Animals; Azides; Benzodiazepines; Brain; Dose-Response Relationship, Drug; Ethanol; Flunitrazepam; Lorazepam; Male; Motor Skills; Rats; Rats, Inbred Strains; Receptors, GABA-A; Species Specificity	1988
Lorazepam administration during embryonic development alters GABAA receptor binding and function. Brain research. Developmental brain research, 1988, Dec-01, Volume: 44, Issue:2 Topics: Animals; Bridged Bicyclo Compounds; Bridged Bicyclo Compounds, Heterocyclic; Cerebral Cortex; Chick Embryo; Chlorides; Embryonic and Fetal Development; Flunitrazepam; Lorazepam; Receptors, GABA-A; Subcellular Fractions	1988
Selective interaction of novel anxiolytics with 5-hydroxytryptamine1A receptors. Biological psychiatry, 1985, Volume: 20, Issue:9 Topics: 8-Hydroxy-2-(di-n-propylamino)tetralin; Animals; Anti-Anxiety Agents; Binding, Competitive; Brain; Buspirone; Cattle; Depression, Chemical; Diazepam; Flunitrazepam; In Vitro Techniques; Lorazepam; Pyrimidines; Receptors, Serotonin; Tetrahydronaphthalenes	1985
[Memory gaps and hypercomplex automatisms after a single oral dose of benzodiazepines: clinical and medico-legal aspects]. Annales medico-psychologiques, 1986, Volume: 144, Issue:1 Topics: Adult; Amnesia; Anti-Anxiety Agents; Automatism; Bromazepam; Drug Synergism; Ethanol; Female; Flunitrazepam; Forensic Psychiatry; France; Humans; Lorazepam; Male	1986
[Abuse of licit drugs in heroin addicts]. La Clinica terapeutica, 1987, Feb-15, Volume: 120, Issue:3 Topics: Adolescent; Adult; Anti-Anxiety Agents; Diazepam; Female; Flunitrazepam; Heroin Dependence; Humans; Lorazepam; Male; Substance-Related Disorders; Surveys and Questionnaires	1987
Evidence of specific benzodiazepine binding to myometrial membrane preparations from human pregnant uterus. Acta obstetricia et gynecologica Scandinavica, 1986, Volume: 65, Issue:4 Topics: Adult; Benzodiazepines; Benzodiazepinones; Cell Membrane; Chlordiazepoxide; Diazepam; Female; Flunitrazepam; Humans; Lorazepam; Myometrium; Pregnancy; Receptors, Cell Surface	1986
[Effect of lormetazepam, triazolam and flunitrazepam on rapid eye movements, K-complexes and sleep spindles in normal probands]. EEG-EMG Zeitschrift fur Elektroenzephalographie, Elektromyographie und verwandte Gebiete, 1987, Volume: 18, Issue:2 Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Electroencephalography; Female; Flunitrazepam; Humans; Lorazepam; Male; Middle Aged; Sleep; Sleep, REM; Triazolam	1987
Simultaneous analysis of antipyrine and lorazepam by high-performance liquid chromatography. Journal of chromatography, 1986, Oct-31, Volume: 382 Topics: Antipyrine; Chromatography, High Pressure Liquid; Flunitrazepam; Humans; Kinetics; Lorazepam; Spectrophotometry, Ultraviolet	1986
Benzodiazepine binding sites in human myometrium. International journal of tissue reactions, 1984, Volume: 6, Issue:5 Topics: Adult; Benzodiazepinones; Binding Sites; Cell Membrane; Clonazepam; Diazepam; Female; Flunitrazepam; Humans; In Vitro Techniques; Lorazepam; Middle Aged; Myometrium; Receptors, GABA-A	1984
The kinetics and displacement of [11C]flunitrazepam in the brain of the living baboon. European journal of pharmacology, 1981, Oct-15, Volume: 75, Issue:1 Topics: Animals; Anti-Anxiety Agents; Blood-Brain Barrier; Brain; Carbon Radioisotopes; Flunitrazepam; Kinetics; Lorazepam; Papio; Receptors, Drug; Receptors, GABA-A; Tomography, Emission-Computed	1981
[Comparative clinical toxicology of 5 benzodiazepine derivatives]. Der Nervenarzt, 1984, Volume: 55, Issue:3 Topics: Adult; Anti-Anxiety Agents; Bromazepam; Child; Coma; Diazepam; Dose-Response Relationship, Drug; Female; Flunitrazepam; Humans; Lorazepam; Male; Metabolic Clearance Rate; Oxazepam; Prognosis; Respiratory Insufficiency; Suicide, Attempted	1984
Pharmacokinetics of benzodiazepines: metabolic pathways and plasma level profiles. Current medical research and opinion, 1984, Volume: 8 Suppl 4 Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Benzodiazepines; Benzodiazepinones; Bromazepam; Child; Clobazam; Flunitrazepam; Flurazepam; Humans; Hydroxylation; Kinetics; Lorazepam; Midazolam; Middle Aged; Nitrazepam; Nordazepam	1984
The effects of benzodiazepines on short-term memory and information processing. Psychopharmacology. Supplementum, 1984, Volume: 1 Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Double-Blind Method; Female; Flunitrazepam; Humans; Lorazepam; Memory, Short-Term; Models, Psychological; Reaction Time; Triazolam	1984
[In vivo study of benzodiazepine receptors using positron emission tomography]. L'Encephale, 1983, Volume: 9, Issue:4 Suppl 2 Topics: Animals; Benzodiazepinones; Binding, Competitive; Brain; Chlordiazepoxide; Flumazenil; Flunitrazepam; Kinetics; Lorazepam; Male; Papio; Receptors, Cell Surface; Receptors, GABA-A; Receptors, Neurotransmitter; Stereoisomerism	1983
Application of radioreceptor assay of benzodiazepines for toxicology. Acta pharmacologica et toxicologica, 1982, Volume: 50, Issue:3 Topics: Animals; Benzodiazepines; Brain; Chromatography, Gas; Flunitrazepam; Humans; In Vitro Techniques; Lorazepam; Membranes; Nitrazepam; Radioligand Assay; Rats	1982
Benzodiazepine withdrawal syndrome seizures. Pharmacopsychiatry, 1995, Volume: 28, Issue:6 Topics: Adult; Anti-Anxiety Agents; Female; Flunitrazepam; Heroin Dependence; Humans; Hypnotics and Sedatives; Lorazepam; Male; Marijuana Abuse; Middle Aged; Risk; Seizures; Substance Withdrawal Syndrome; Substance-Related Disorders; Triazolam	1995
Detection of benzodiazepines and other psychotropic drugs in human hair by GC/MS. Forensic science international, 1997, Jan-17, Volume: 84, Issue:1-3 Topics: Adult; Anti-Anxiety Agents; Benzodiazepines; Drug Overdose; Female; Flunitrazepam; Gas Chromatography-Mass Spectrometry; Hair; Humans; Lorazepam; Male; Middle Aged; Oxazepam; Psychotropic Drugs	1997
Sequestration of gamma-aminobutyric acidA receptors on clathrin-coated vesicles during chronic benzodiazepine administration in vivo. The Journal of pharmacology and experimental therapeutics, 1997, Volume: 283, Issue:1 Topics: Animals; Anti-Anxiety Agents; Brain; Clathrin; Flunitrazepam; Lorazepam; Mice; Mice, Inbred C57BL; Molecular Weight; Receptors, GABA-A	1997
Single- and repeated-dose local toxicity in the nasal cavity of rabbits after intranasal administration of different glycols for formulations containing benzodiazepines. The Journal of pharmacy and pharmacology, 1999, Volume: 51, Issue:4 Topics: Administration, Intranasal; Animals; Anti-Anxiety Agents; Benzodiazepines; Chemistry, Pharmaceutical; Clonazepam; Diazepam; Dose-Response Relationship, Drug; Drug Evaluation; Flunitrazepam; Lorazepam; Nasal Cavity; Pharmaceutic Aids; Polyethylene Glycols; Rabbits; Time Factors	1999
Convulsive status epilepticus following abrupt high-dose benzodiazepine discontinuation. Drug and alcohol dependence, 2000, Apr-01, Volume: 59, Issue:1 Topics: Adult; Anti-Anxiety Agents; Dose-Response Relationship, Drug; Epilepsy, Tonic-Clonic; Female; Flunitrazepam; Humans; Long-Term Care; Lorazepam; Male; Middle Aged; Status Epilepticus; Substance Withdrawal Syndrome	2000
Sexual assault under benzodiazepine submission in a Paris suburb. Archives of gynecology and obstetrics, 2000, Volume: 263, Issue:4 Topics: Adolescent; Adult; Anti-Anxiety Agents; Benzodiazepines; Cocaine; Dronabinol; Estazolam; Female; Flunitrazepam; Humans; Hypnotics and Sedatives; Immunoassay; Lorazepam; Male; Morphine; Narcotics; Nitrazepam; Paris; Rape; Retrospective Studies; Substance-Related Disorders; Temazepam; Time Factors; Triazolam	2000
Acute zolpidem administration produces pharmacodynamic and receptor occupancy changes at similar doses. Pharmacology, biochemistry, and behavior, 2006, Volume: 83, Issue:1 Topics: Animals; Anticonvulsants; Binding, Competitive; Convulsants; Dose-Response Relationship, Drug; Flunitrazepam; Hypnotics and Sedatives; Lorazepam; Male; Mice; Motor Activity; Pentylenetetrazole; Pyridines; Receptors, Drug; Receptors, GABA-A; Seizures; Zolpidem	2006
Simultaneous determination and quantification of 12 benzodiazepines in serum or whole blood using UPLC/MS/MS. Methods in molecular biology (Clifton, N.J.), 2010, Volume: 603 Topics: Alprazolam; Benzodiazepines; Chlordiazepoxide; Chromatography, Liquid; Clonazepam; Flunitrazepam; Humans; Lorazepam; Midazolam; Nordazepam; Oxazepam; Reproducibility of Results; Tandem Mass Spectrometry	2010
A tendency for re-offending in drug-facilitated crime. Forensic science international, 2010, Mar-20, Volume: 196, Issue:1-3 Topics: Adult; Anti-Anxiety Agents; Chromatography, Liquid; Clonazepam; Crime Victims; Doxylamine; Drug Combinations; Female; Flunitrazepam; Forensic Toxicology; Hair; Humans; Hypnotics and Sedatives; Limit of Detection; Lorazepam; Male; Mass Spectrometry; Middle Aged; Phenothiazines; Pyridines; Rape; Recurrence; Zolpidem	2010