lorazepam and dexmedetomidine

lorazepam has been researched along with dexmedetomidine in 33 studies

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's13 (39.39)29.6817
2010's19 (57.58)24.3611
2020's1 (3.03)2.80

Authors

AuthorsStudies
Lombardo, F; Obach, RS; Waters, NJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Cavaliere, F; Maze, M; Scarfini, C1
Maccioli, GA1
Multz, AS1
Dasta, JF; Jacobi, J; McLaughlin, TP; Sesti, AM1
Forrest, LK; Kiser, TH; MacLaren, R1
Bernard, GR; Deppen, SA; Dittus, RS; Ely, EW; Girard, TD; Herr, DL; Jackson, JC; Maze, M; Miller, RR; Pandharipande, PP; Pun, BT; Shintani, AK; Stiles, RA; Thompson, JL1
Meltzer, JS; Wunsch, H1
Dotson, B; Peeters, MJ1
Barletta, JF; Devlin, JW1
Areosa Sastre, A; Lonergan, E; Luxenberg, J; Wyller, TB1
Areosa Sastre, A; Lonergan, E; Luxenberg, J1
Short, J1
Hanling, S; Mecklenburg, B; Wallace, S1
Ely, EW; Girard, TD; Herr, DL; Maze, M; McGrane, S; Pandharipande, PP; Sanders, RD; Shintani, AK; Thompson, JL1
Kress, JP1
Frontera, JA1
Cheifetz, IM; Turner, DA; Walgos, J; Watt, KM1
Akingbola, OA; Singh, D1
Fish, DN; Kiser, TH; Lavelle, JC; MacLaren, R; Malkoski, SP; Mueller, SW; Preslaski, CR1
Kupfer, Y; Savel, RH1
Brown, CV; Crispo, AL; Daley, MJ; Harford, PH; Pepin, JL1
Cai, Y; Chen, K; Chen, Y; Lu, Z; Pan, SM; Xin, YC1
Adjepong, YA; Lukens, C; Manthous, CA; Musial, B; Perez, R; Stewart, R1
Dziodzio, JT; Fontaine, GV; Fraser, GL; Gagnon, DJ; Lerwick, PA; Lucas, FL; Miller, RR; Riker, RR; Sihler, KC; Smith, KE1
Benowitz, NL; Horng, H; Smollin, CG; Vo, KT1
Brunkhorst, J; Carter, BS1
Bailey, AM; Baum, RA; Horn, K; Justice, SN; Lewis, T; Morizio, K; Schultz, A; Weant, K1
Ely, EW; Ferrell, BA; Girard, TD; Hughes, CG; Pandharipande, PP; Patel, MB; Scheinin, M; Shintani, AK; Stollings, JL; Thompson, JL; Wilkinson, GR1
Joynt, GM; Lee, A; Ling, L; Tse, AHW1
Hardman, MI; Sprung, J; Weingarten, TN1
Miskimins, R; Mitchell, J; Sarangarm, P; Wiemann, B1

Reviews

10 review(s) available for lorazepam and dexmedetomidine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
New agents for sedation in the intensive care unit.
    Critical care clinics, 2001, Volume: 17, Issue:4

    Topics: Adrenergic alpha-Agonists; Anti-Anxiety Agents; Critical Illness; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Piperidines; Receptors, Adrenergic, alpha; Remifentanil

2001
Benzodiazepines for delirium.
    The Cochrane database of systematic reviews, 2009, Jan-21, Issue:1

    Topics: Benzodiazepines; Delirium; Dexmedetomidine; Humans; Lorazepam

2009
Benzodiazepines for delirium.
    The Cochrane database of systematic reviews, 2009, Oct-07, Issue:4

    Topics: Benzodiazepines; Delirium; Dexmedetomidine; Humans; Lorazepam

2009
Delirium and sedation in the ICU.
    Neurocritical care, 2011, Volume: 14, Issue:3

    Topics: Conscious Sedation; Delirium; Dexmedetomidine; Diagnosis, Differential; Hospital Mortality; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Midazolam; Neurologic Examination; Prognosis; Risk Factors; Survival Rate

2011
Alpha-2 agonists for long-term sedation during mechanical ventilation in critically ill patients.
    The Cochrane database of systematic reviews, 2015, Jan-06, Volume: 1

    Topics: Adrenergic alpha-2 Receptor Agonists; Adult; Bradycardia; Clonidine; Conscious Sedation; Critical Illness; Dexmedetomidine; Humans; Lorazepam; Midazolam; Propofol; Randomized Controlled Trials as Topic; Respiration, Artificial; Selection Bias; Time Factors

2015
Neonatal pain management.
    Seminars in perinatology, 2017, Volume: 41, Issue:2

    Topics: Amines; Analgesics, Opioid; Anti-Anxiety Agents; Barbiturates; Chronic Pain; Cyclohexanecarboxylic Acids; Dexmedetomidine; Gabapentin; gamma-Aminobutyric Acid; Humans; Hypnotics and Sedatives; Infant, Newborn; Intensive Care Units, Neonatal; Kangaroo-Mother Care Method; Ketamine; Lorazepam; Midazolam; Neonatal Abstinence Syndrome; Pain Management; Pain Measurement; Palliative Care; Propofol; Sucking Behavior; Sucrose; Terminal Care

2017
Review of Intranasally Administered Medications for Use in the Emergency Department.
    The Journal of emergency medicine, 2017, Volume: 53, Issue:1

    Topics: Administration, Intranasal; Anesthetics, Dissociative; Anticonvulsants; Antidotes; Antipsychotic Agents; Dexmedetomidine; Emergency Service, Hospital; Fentanyl; Flumazenil; Haloperidol; Humans; Hydromorphone; Hypnotics and Sedatives; Ketamine; Lorazepam; Midazolam; Naloxone; Narcotic Antagonists; Narcotics

2017
Altered Pharmacokinetics in Prolonged Infusions of Sedatives and Analgesics Among Adult Critically Ill Patients: A Systematic Review.
    Clinical therapeutics, 2018, Volume: 40, Issue:9

    Topics: Adult; Analgesics; Critical Illness; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lorazepam; Midazolam; Morphine; Propofol; Remifentanil; Sufentanil; Time Factors

2018
Acute phenibut withdrawal: A comprehensive literature review and illustrative case report.
    Bosnian journal of basic medical sciences, 2019, May-20, Volume: 19, Issue:2

    Topics: Akathisia, Drug-Induced; Baclofen; Cyproheptadine; Dexmedetomidine; Diphenhydramine; GABA-A Receptor Antagonists; GABA-B Receptor Agonists; gamma-Aminobutyric Acid; Haloperidol; Humans; Lorazepam; Male; Melatonin; Neuroleptic Malignant Syndrome; Olanzapine; Receptors, GABA; Substance Withdrawal Syndrome; Substance-Related Disorders; Young Adult

2019

Trials

5 trial(s) available for lorazepam and dexmedetomidine

ArticleYear
Effect of sedation with dexmedetomidine vs lorazepam on acute brain dysfunction in mechanically ventilated patients: the MENDS randomized controlled trial.
    JAMA, 2007, Dec-12, Volume: 298, Issue:22

    Topics: Aged; Coma; Conscious Sedation; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Male; Middle Aged; Neuropsychological Tests; Respiration, Artificial

2007
Use of dexmedetomidine for primary sedation in a general intensive care unit.
    Critical care nurse, 2010, Volume: 30, Issue:1

    Topics: Adrenergic alpha-Agonists; Analgesics, Non-Narcotic; Clinical Nursing Research; Clinical Protocols; Conscious Sedation; Critical Care; Dexmedetomidine; Drug Monitoring; Drug Utilization; Humans; Hypnotics and Sedatives; Kansas; Length of Stay; Lorazepam; Midazolam; Nursing Assessment; Propofol; Respiration, Artificial; Safety; Treatment Outcome

2010
Effect of dexmedetomidine versus lorazepam on outcome in patients with sepsis: an a priori-designed analysis of the MENDS randomized controlled trial.
    Critical care (London, England), 2010, Volume: 14, Issue:2

    Topics: Adult; Aged; Coma; Delirium; Dexmedetomidine; Double-Blind Method; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Male; Middle Aged; Outcome Assessment, Health Care; Respiration, Artificial; Sepsis

2010
A randomized, double-blind, placebo-controlled dose range study of dexmedetomidine as adjunctive therapy for alcohol withdrawal.
    Critical care medicine, 2014, Volume: 42, Issue:5

    Topics: Adult; Anticonvulsants; Dexmedetomidine; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; Ethanol; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Lorazepam; Middle Aged; Prospective Studies; Statistics, Nonparametric; Substance Withdrawal Syndrome

2014
Sedative Plasma Concentrations and Delirium Risk in Critical Illness.
    The Annals of pharmacotherapy, 2018, Volume: 52, Issue:6

    Topics: Aged; Critical Illness; Delirium; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Intensive Care Units; Logistic Models; Lorazepam; Male; Middle Aged; Respiration, Artificial

2018

Other Studies

18 other study(ies) available for lorazepam and dexmedetomidine

ArticleYear
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Dexmedetomidine to facilitate drug withdrawal.
    Anesthesiology, 2003, Volume: 98, Issue:2

    Topics: Alcohol Drinking; Blood Pressure; Cocaine-Related Disorders; Dexmedetomidine; Female; Heart Rate; Humans; Hypertension; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Psychomotor Agitation; Respiration, Artificial; Substance Withdrawal Syndrome

2003
Prolonged dexmedetomidine infusion as an adjunct in treating sedation-induced withdrawal.
    Anesthesia and analgesia, 2003, Volume: 96, Issue:4

    Topics: Acinetobacter Infections; Adult; Analgesics, Opioid; Dexmedetomidine; Fentanyl; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lorazepam; Male; Pneumonia; Psychomotor Agitation; Respiratory Distress Syndrome; Substance Withdrawal Syndrome; Substance-Related Disorders; Ventilator Weaning; Ventilators, Mechanical

2003
Addition of dexmedetomidine to standard sedation regimens after cardiac surgery: an outcomes analysis.
    Pharmacotherapy, 2006, Volume: 26, Issue:6

    Topics: Aged; Cardiac Surgical Procedures; Dexmedetomidine; Drug Therapy, Combination; Female; Hospitals; Humans; Hypnotics and Sedatives; Intensive Care Units; Length of Stay; Lorazepam; Male; Midazolam; Middle Aged; Outcome Assessment, Health Care; Propofol; Retrospective Studies

2006
Adjunctive dexmedetomidine therapy in the intensive care unit: a retrospective assessment of impact on sedative and analgesic requirements, levels of sedation and analgesia, and ventilatory and hemodynamic parameters.
    Pharmacotherapy, 2007, Volume: 27, Issue:3

    Topics: Anesthetics; Databases as Topic; Dexmedetomidine; Female; Fentanyl; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Lorazepam; Male; Middle Aged; Propofol; Respiration; Retrospective Studies

2007
Sedation with dexmedetomidine vs lorazepam in mechanically ventilated patients.
    JAMA, 2008, Apr-02, Volume: 299, Issue:13

    Topics: Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Lorazepam; Research Design; Respiration, Artificial

2008
Sedation with dexmedetomidine vs lorazepam in mechanically ventilated patients.
    JAMA, 2008, Apr-02, Volume: 299, Issue:13

    Topics: Conscious Sedation; Dexmedetomidine; Humans; Hypnotics and Sedatives; Lorazepam; Respiration, Artificial

2008
Sedation with dexmedetomidine vs lorazepam in mechanically ventilated patients.
    JAMA, 2008, Apr-02, Volume: 299, Issue:13

    Topics: Conscious Sedation; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Lorazepam; Research Design; Respiration, Artificial

2008
Profound reduction in sedation and analgesic requirements using extended dexmedetomidine infusions in a patient with an open abdomen.
    Military medicine, 2009, Volume: 174, Issue:11

    Topics: Abdominal Injuries; Analgesics, Non-Narcotic; Dexmedetomidine; Fentanyl; Humans; Infusions, Intravenous; Lorazepam; Male; Midazolam; Military Personnel; Pain Measurement; Propofol; Stress Disorders, Post-Traumatic; Wounds, Gunshot; Young Adult

2009
The complex interplay between delirium, sepsis and sedation.
    Critical care (London, England), 2010, Volume: 14, Issue:3

    Topics: Brain; Critical Illness; Delirium; Dexmedetomidine; Humans; Hypnotics and Sedatives; Intensive Care Units; Lorazepam; Outcome Assessment, Health Care; Randomized Controlled Trials as Topic; Respiration, Artificial; Sepsis

2010
Dexmedetomidine for transport of a spontaneously breathing combative child.
    Pediatrics, 2012, Volume: 130, Issue:3

    Topics: Child, Preschool; Dexmedetomidine; Humans; Hypnotics and Sedatives; Lorazepam; Male; Mental Disorders; Psychomotor Agitation; Transportation of Patients

2012
Dexmedetomidine to treat lisdexamfetamine overdose and serotonin toxidrome in a 6-year-old girl.
    American journal of critical care : an official publication, American Association of Critical-Care Nurses, 2012, Volume: 21, Issue:6

    Topics: Adrenergic alpha-2 Receptor Agonists; Anti-Anxiety Agents; Central Nervous System Stimulants; Child; Dexmedetomidine; Dextroamphetamine; Drug Overdose; Female; Humans; Lisdexamfetamine Dimesylate; Lorazepam; Midazolam; Serotonin Syndrome

2012
Using dexmedetomidine as adjunctive therapy for patients with severe alcohol withdrawal syndrome: another piece of the puzzle.
    Critical care medicine, 2014, Volume: 42, Issue:5

    Topics: Anticonvulsants; Dexmedetomidine; Ethanol; Humans; Hypnotics and Sedatives; Lorazepam; Substance Withdrawal Syndrome

2014
Comparison of clinical outcomes in nonintubated patients with severe alcohol withdrawal syndrome treated with continuous-infusion sedatives: dexmedetomidine versus benzodiazepines.
    Pharmacotherapy, 2014, Volume: 34, Issue:9

    Topics: Adult; Aged; Benzodiazepines; Cohort Studies; Dexmedetomidine; Ethanol; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Lorazepam; Male; Midazolam; Middle Aged; Retrospective Studies; Severity of Illness Index; Substance Withdrawal Syndrome; Treatment Outcome

2014
Outcomes of Patients with Alcohol Withdrawal Syndrome Treated with High-Dose Sedatives and Deferred Intubation.
    Annals of the American Thoracic Society, 2016, Volume: 13, Issue:2

    Topics: Adult; Alcohol Withdrawal Seizures; APACHE; Central Nervous System Depressants; Cohort Studies; Critical Illness; Dexmedetomidine; Ethanol; Female; Humans; Hypnotics and Sedatives; Infusions, Intravenous; Intensive Care Units; Intubation, Intratracheal; Length of Stay; Logistic Models; Lorazepam; Male; Midazolam; Middle Aged; Pneumonia; Propofol; Respiration, Artificial; Retrospective Studies; Substance Withdrawal Syndrome; Time Factors; Treatment Outcome

2016
Valproate for agitation in critically ill patients: A retrospective study.
    Journal of critical care, 2017, Volume: 37

    Topics: Adult; Aged; Analgesics, Opioid; Critical Illness; Delirium; Dexmedetomidine; Female; Fentanyl; GABA Agents; Humans; Hypnotics and Sedatives; Lorazepam; Male; Middle Aged; Psychomotor Agitation; Retrospective Studies; Valproic Acid

2017
Severe Carisoprodol Withdrawal After a 14-Year Addiction and Acute Overdose.
    The Journal of emergency medicine, 2017, Volume: 52, Issue:5

    Topics: Adult; Carisoprodol; Dexmedetomidine; Drug Overdose; Fentanyl; Haloperidol; Humans; Hypnotics and Sedatives; Intensive Care Units; Ketamine; Lorazepam; Male; Midazolam; Propofol; Quetiapine Fumarate; Respiration, Artificial; Substance Withdrawal Syndrome; Substance-Related Disorders

2017
Tracheotomy in ventilator-dependent patients with COVID-19: a cross-sectional study of analgesia and sedative requirements.
    The Journal of international medical research, 2022, Volume: 50, Issue:11

    Topics: Analgesia; Analgesics; COVID-19; Cross-Sectional Studies; Dexmedetomidine; Humans; Hypnotics and Sedatives; Lorazepam; Morphine; Pain; Propofol; Retrospective Studies; Tracheotomy; Ventilators, Mechanical

2022