lorazepam and desipramine

lorazepam has been researched along with desipramine in 21 studies

Research

Studies (21)

Timeframe	Studies, this research(%)	All Research%
pre-1990	4 (19.05)	18.7374
1990's	2 (9.52)	18.2507
2000's	11 (52.38)	29.6817
2010's	4 (19.05)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Andrews, PR; Craik, DJ; Martin, JL	1
Strassburg, CP; Tukey, RH	1
Duffy, EM; Jorgensen, WL	1
Topliss, JG; Yoshida, F	1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA	1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY	2
Lombardo, F; Obach, RS; Waters, NJ	1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z	1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV	1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM	1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV	1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ	1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K	1
Lambert, MT	1
Bonea, M; Da Rold, A; Maffei Faccioli, A; Manfè, AZ; Terranova, O	1
Dugas, JE; Glassman, JN; Loyd, DW; Tsuang, MT	1
Rosenblatt, JE	1
Coplan, JD; Gorman, JM; Papp, LA; Tiffon, L	1
Birkenhager, TK; Bruijn, JA; Moleman, P; Mulder, PG; van den Broek, WW	1
Konishi, K; Minematsu, T; Nagasaka, Y; Tabata, K	1

Reviews

2 review(s) available for lorazepam and desipramine

Article	Year
Human UDP-glucuronosyltransferases: metabolism, expression, and disease. Annual review of pharmacology and toxicology, 2000, Volume: 40 Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic	2000
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans. Drug discovery today, 2016, Volume: 21, Issue:4 Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk	2016

Other Studies

19 other study(ies) available for lorazepam and desipramine

Article	Year
Functional group contributions to drug-receptor interactions. Journal of medicinal chemistry, 1984, Volume: 27, Issue:12 Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship	1984
Prediction of drug solubility from Monte Carlo simulations. Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11 Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility	2000
QSAR model for drug human oral bioavailability. Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13 Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship	2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds. Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15 Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water	2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data. Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13 Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding	2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics. Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5 Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution	2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds. Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7 Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding	2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human. European journal of medicinal chemistry, 2009, Volume: 44, Issue:4 Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software	2009
Physicochemical determinants of human renal clearance. Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15 Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight	2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models. Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3 Topics:	2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination. Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3 Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations	2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species. Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6 Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics	2010
Pheochromocytoma presenting as exacerbation of post traumatic stress disorder symptomology. International journal of psychiatry in medicine, 1992, Volume: 22, Issue:3 Topics: Adrenal Gland Neoplasms; Adult; Blood Pressure; Combat Disorders; Desipramine; Diagnostic Errors; Hospitalization; Humans; Lorazepam; Male; Metanephrine; Pheochromocytoma; Psychiatric Status Rating Scales; Stress Disorders, Post-Traumatic	1992
[A case of dynamic ileus caused by tricyclic antidepressive agents]. Minerva chirurgica, 1988, Dec-31, Volume: 43, Issue:23-24 Topics: Antidepressive Agents, Tricyclic; Depression; Desipramine; Drug Therapy, Combination; Female; Humans; Ileal Diseases; Imipramine; Intestinal Obstruction; Lorazepam; Middle Aged	1988
Idiosyncratic pharmacokinetics complicating treatment of major depression in an elderly woman. The Journal of nervous and mental disease, 1985, Volume: 173, Issue:9 Topics: Depressive Disorder; Desipramine; Diphenhydramine; Female; Half-Life; Hospitalization; Humans; Kinetics; Lorazepam; Metabolism, Inborn Errors; Middle Aged	1985
Lorazepam and desipramine serum concentration. The American journal of psychiatry, 1982, Volume: 139, Issue:4 Topics: Aged; Anti-Anxiety Agents; Depressive Disorder; Desipramine; Drug Interactions; Female; Humans; Lorazepam	1982
Augmentation strategies with tricyclic or fluoxetine treatment in seven partially responsive panic disorder patients. The Journal of clinical psychiatry, 1994, Volume: 55, Issue:2 Topics: Adult; Alprazolam; Antidepressive Agents, Tricyclic; Desipramine; Drug Therapy, Combination; Female; Fluoxetine; Humans; Imipramine; Lorazepam; Male; Panic Disorder; Retrospective Studies; Treatment Outcome	1994
Efficacy of imipramine in psychotic versus nonpsychotic depression. Journal of clinical psychopharmacology, 2008, Volume: 28, Issue:2 Topics: Adult; Affective Disorders, Psychotic; Aged; Antidepressive Agents; Data Interpretation, Statistical; Depressive Disorder; Desipramine; Diagnostic and Statistical Manual of Mental Disorders; Drug Administration Schedule; Drug Therapy, Combination; Female; Haloperidol; Humans; Imipramine; Logistic Models; Lorazepam; Male; Middle Aged; Psychiatric Status Rating Scales; Randomized Controlled Trials as Topic; Time Factors; Treatment Outcome	2008
Application of a physiologically based pharmacokinetic model for the prediction of mirabegron plasma concentrations in a population with severe renal impairment. Biopharmaceutics & drug disposition, 2019, Volume: 40, Issue:5-6 Topics: Acetanilides; Adolescent; Adrenergic beta-3 Receptor Agonists; Adult; Aged; Aging; Butyrylcholinesterase; Cytochrome P-450 CYP2D6 Inhibitors; Cytochrome P-450 CYP3A; Cytochrome P-450 CYP3A Inhibitors; Desipramine; Drug Interactions; Female; Gemfibrozil; Glucuronosyltransferase; Humans; Itraconazole; Lorazepam; Male; Middle Aged; Models, Biological; Renal Insufficiency; Thiazoles; Young Adult; Zidovudine	2019