lorazepam has been researched along with cimetidine in 18 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (33.33) | 18.7374 |
| 1990's | 1 (5.56) | 18.2507 |
| 2000's | 8 (44.44) | 29.6817 |
| 2010's | 3 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Topliss, JG; Yoshida, F | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY | 2 |
| Chang, TK; Ensom, MH; Kiang, TK | 1 |
| Lombardo, F; Obach, RS; Waters, NJ | 1 |
| Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV | 1 |
| Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
| Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV | 1 |
| García-Mera, X; González-Díaz, H; Prado-Prado, FJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Doenicke, A; Dorow, R; Täuber, U | 1 |
| Desmond, PV; Johnson, RF; Patwardhan, RV; Schenker, S; Speeg, KV; Yarborough, GW | 1 |
| Ruffalo, RL; Segal, JL; Thompson, JF | 1 |
| Dundee, JW; McGowan, WA | 1 |
| Abernethy, DR; Greenblatt, DJ; Koepke, HH; Shader, RI | 1 |
| Abernethy, DR; Ameer, B; Divoll, M; Greenblatt, DJ; Shader, RI | 1 |
| File, SE; Pearce, JB | 1 |
3 review(s) available for lorazepam and cimetidine
| Article | Year |
|---|---|
UDP-glucuronosyltransferases and clinical drug-drug interactions.
Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic | 2005 |
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
Diazepam-cimetidine drug interaction: a clinically significant effect.
Topics: Anti-Anxiety Agents; Cimetidine; Cytochrome P-450 Enzyme System; Depression, Chemical; Diazepam; Drug Interactions; Guanidines; Humans; Kinetics; Lorazepam; Oxazepam; Oxidation-Reduction | 1981 |
2 trial(s) available for lorazepam and cimetidine
| Article | Year |
|---|---|
[The pharmacokinetics of lormetazepam following cimetidine].
Topics: Anti-Anxiety Agents; Benzodiazepines; Cimetidine; Female; Humans; Lorazepam; Male | 1991 |
The effect of intravenous cimetidine on the absorption of orally administered diazepam and lorazepam.
Topics: Administration, Oral; Adult; Anti-Anxiety Agents; Capsules; Cimetidine; Diazepam; Drug Interactions; Female; Guanidines; Humans; Injections, Intravenous; Intestinal Absorption; Lorazepam; Tablets | 1982 |
13 other study(ies) available for lorazepam and cimetidine
| Article | Year |
|---|---|
QSAR model for drug human oral bioavailability.
Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship | 2000 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding | 2002 |
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution | 2004 |
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding | 2008 |
Physicochemical determinants of human renal clearance.
Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight | 2009 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations | 2010 |
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics | 2010 |
Cimetidine spares the glucuronidation of lorazepam and oxazepam.
Topics: Adult; Anti-Anxiety Agents; Biotransformation; Cimetidine; Drug Interactions; Female; Glucuronates; Guanidines; Humans; Lorazepam; Male; Oxazepam | 1980 |
Interaction of cimetidine with oxazepam, lorazepam, and flurazepam.
Topics: Adult; Anti-Anxiety Agents; Biotransformation; Cimetidine; Female; Flurazepam; Half-Life; Humans; Kinetics; Lorazepam; Male; Microsomes, Liver; Oxazepam | 1984 |
Differential effect of cimetidine on drug oxidation (antipyrine and diazepam) vs. conjugation (acetaminophen and lorazepam): prevention of acetaminophen toxicity by cimetidine.
Topics: Acetaminophen; Adult; Animals; Antipyrine; Biotransformation; Cimetidine; Diazepam; Guanidines; Humans; Kinetics; Lethal Dose 50; Lorazepam; Male; Mice; Oxidation-Reduction | 1983 |
Benzodiazepines reduce gastric ulcers induced in rats by stress.
Topics: Animals; Atropine; Benzodiazepines; Chlordiazepoxide; Cimetidine; Female; Gastric Acid; Gastric Mucosa; Hypnotics and Sedatives; In Vitro Techniques; Lorazepam; Male; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological | 1981 |