lorazepam and atropine

lorazepam has been researched along with atropine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-19905 (26.32)18.7374
1990's2 (10.53)18.2507
2000's8 (42.11)29.6817
2010's4 (21.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Andrews, PR; Craik, DJ; Martin, JL1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Lombardo, F; Obach, RS; Waters, NJ1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Bellville, JW; Conner, JT; Graham, CW; Katz, RL; Pagano, RR; Schehl, D1
Edwards, AE; Ferguson, BJ; Gower, DE; Smith, CJ; Williams, CP1
Auvinen, J; Korttila, K; Levänen, J1
File, SE; Pearce, JB1
Lumley, J; Morgan, M; Puchihewa, VG; Whitwam, JG1
Cole, BJ; Jones, GH1
Akhileswaran, R; Heng, CP; Hui, D; Tan, A; Yap, R1

Reviews

1 review(s) available for lorazepam and atropine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for lorazepam and atropine

ArticleYear
Lorazepam, hyoscine and atropine as i.v. surgical premedicants.
    British journal of anaesthesia, 1978, Volume: 50, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anxiety; Atropine; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Infusions, Parenteral; Lorazepam; Male; Mental Recall; Middle Aged; Preanesthetic Medication; Scopolamine

1978

Other Studies

17 other study(ies) available for lorazepam and atropine

ArticleYear
Functional group contributions to drug-receptor interactions.
    Journal of medicinal chemistry, 1984, Volume: 27, Issue:12

    Topics: Animals; Calorimetry; Kinetics; Models, Biological; Protein Binding; Receptors, Cell Surface; Receptors, Drug; Structure-Activity Relationship

1984
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Leucocyte migration: effects of in vitro exposure to anaesthetic agents: possible potentiation of effects by adrenaline.
    European journal of anaesthesiology, 1992, Volume: 9, Issue:6

    Topics: Adult; Anesthetics; Atropine; Bupivacaine; Cell Migration Inhibition; Cell Movement; Cell Survival; Drug Synergism; Epinephrine; Humans; Hydrocortisone; Leukocytes; Lidocaine; Lorazepam; Lymphocytes; Middle Aged; Morphine; Norepinephrine; Pancuronium; Succinylcholine; Thiopental

1992
Failure of intramuscularly administered lorazepam and scopolamine-morphine premedication to produce amnesic effects to supplement conduction anaesthesia.
    Acta anaesthesiologica Scandinavica, 1980, Volume: 24, Issue:4

    Topics: Adult; Anesthesia, Conduction; Anti-Anxiety Agents; Atropine; Humans; Injections, Intramuscular; Lorazepam; Male; Memory; Meperidine; Morphine; Preanesthetic Medication; Scopolamine

1980
Benzodiazepines reduce gastric ulcers induced in rats by stress.
    British journal of pharmacology, 1981, Volume: 74, Issue:3

    Topics: Animals; Atropine; Benzodiazepines; Chlordiazepoxide; Cimetidine; Female; Gastric Acid; Gastric Mucosa; Hypnotics and Sedatives; In Vitro Techniques; Lorazepam; Male; Rats; Rats, Inbred Strains; Stomach Ulcer; Stress, Physiological

1981
Respiratory effects of Minaxolone.
    Anaesthesia, 1980, Volume: 35, Issue:6

    Topics: Anesthesia, Intravenous; Anesthetics; Apnea; Atropine; Female; Humans; Lorazepam; Lung Volume Measurements; Papaverine; Preanesthetic Medication; Pregnanes; Pregnanolone; Respiration; Scopolamine

1980
Double dissociation between the effects of muscarinic antagonists and benzodiazepine receptor agonists on the acquisition and retention of passive avoidance.
    Psychopharmacology, 1995, Volume: 118, Issue:1

    Topics: Animals; Atropine; Avoidance Learning; Diazepam; GABA-A Receptor Agonists; Lorazepam; Male; Memory; Muscarinic Antagonists; Rats; Rats, Wistar; Scopolamine

1995
Comfort care kit: use of nonoral and nonparenteral rescue medications at home for terminally ill patients with swallowing difficulty.
    Journal of palliative medicine, 2014, Volume: 17, Issue:5

    Topics: Acetaminophen; Adjuvants, Anesthesia; Administration, Rectal; Administration, Sublingual; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Anxiety Agents; Antipsychotic Agents; Atropine; Caregivers; Deglutition Disorders; Female; Haloperidol; Home Care Services; Humans; Lorazepam; Male; Middle Aged; Morphine; Palliative Care; Pilot Projects; Singapore; Terminally Ill

2014