lorazepam and acetaminophen

lorazepam has been researched along with acetaminophen in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19905 (17.86)18.7374
1990's1 (3.57)18.2507
2000's16 (57.14)29.6817
2010's5 (17.86)24.3611
2020's1 (3.57)2.80

Authors

AuthorsStudies
Strassburg, CP; Tukey, RH1
Duffy, EM; Jorgensen, WL1
Topliss, JG; Yoshida, F1
Abraham, MH; Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Gao, F; Lombardo, F; Obach, RS; Shalaeva, MY2
Chang, TK; Ensom, MH; Kiang, TK1
Lombardo, F; Obach, RS; Waters, NJ1
He, Z; Li, H; Liu, J; Liu, X; Sui, X; Sun, J; Sun, Y; Yan, Z1
Chupka, J; El-Kattan, A; Feng, B; Miller, HR; Obach, RS; Troutman, MD; Varma, MV1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Chang, G; El-Kattan, A; Miller, HR; Obach, RS; Rotter, C; Steyn, SJ; Troutman, MD; Varma, MV1
García-Mera, X; González-Díaz, H; Prado-Prado, FJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Blyden, GT; Greenblatt, DJ; Scavone, JM1
Engelking, LR; Greenblatt, DJ1
Abernethy, DR; Ameer, B; Greenblatt, DJ; Shader, RI1
Abernethy, DR; Divoll, M; Greenblatt, DJ; Shader, RI1
Abernethy, DR; Ameer, B; Divoll, M; Greenblatt, DJ; Shader, RI1
Greenblatt, DJ; Harmatz, JS; Manis, M; Poorman, R; von Moltke, LL1
Clifford, TJ; Neto, GM; Plint, A; Randhawa, N; Reid, SM1
Collins, CH; Collins, KE; Faria, AM1
Bird, S; Cohen, J; Ganetsky, M; Kent, K1
Khan, KH; Tham, TC1
Bayerl, MG; Claxton, DF; Liao, J; Talamo, G; Zangari, M1
Akhileswaran, R; Heng, CP; Hui, D; Tan, A; Yap, R1
Alsubih, M; Balakrishnan, D; El Morabet, R; Khan, AR; Khan, NA; Khan, RA; Khan, S; Khoo, KS; Mubashir, M1

Reviews

3 review(s) available for lorazepam and acetaminophen

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia; Neoplasms; Steroids; Terminology as Topic

2000
UDP-glucuronosyltransferases and clinical drug-drug interactions.
    Pharmacology & therapeutics, 2005, Volume: 106, Issue:1

    Topics: Clinical Trials as Topic; Drug Interactions; Enzyme Activation; Enzyme Induction; Glucuronides; Glucuronosyltransferase; Humans; Pharmaceutical Preparations; Pharmacogenetics; Polymorphism, Genetic

2005
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for lorazepam and acetaminophen

ArticleYear
Oral administration of analgesia and anxiolysis for pain associated with bone marrow biopsy.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2010, Volume: 18, Issue:3

    Topics: Acetaminophen; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics; Anesthesia, Local; Anti-Anxiety Agents; Biopsy, Needle; Bone Marrow; Female; Humans; Lorazepam; Male; Middle Aged; Oxycodone; Pain; Pain Measurement

2010

Other Studies

24 other study(ies) available for lorazepam and acetaminophen

ArticleYear
Prediction of drug solubility from Monte Carlo simulations.
    Bioorganic & medicinal chemistry letters, 2000, Jun-05, Volume: 10, Issue:11

    Topics: Monte Carlo Method; Pharmaceutical Preparations; Solubility

2000
QSAR model for drug human oral bioavailability.
    Journal of medicinal chemistry, 2000, Jun-29, Volume: 43, Issue:13

    Topics: Administration, Oral; Biological Availability; Humans; Models, Biological; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
ElogPoct: a tool for lipophilicity determination in drug discovery.
    Journal of medicinal chemistry, 2000, Jul-27, Volume: 43, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Solvents

2000
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Prediction of volume of distribution values in humans for neutral and basic drugs using physicochemical measurements and plasma protein binding data.
    Journal of medicinal chemistry, 2002, Jun-20, Volume: 45, Issue:13

    Topics: Blood Proteins; Chemical Phenomena; Chemistry, Physical; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding

2002
Prediction of human volume of distribution values for neutral and basic drugs. 2. Extended data set and leave-class-out statistics.
    Journal of medicinal chemistry, 2004, Feb-26, Volume: 47, Issue:5

    Topics: Algorithms; Blood Proteins; Half-Life; Humans; Hydrogen-Ion Concentration; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Protein Binding; Statistics as Topic; Tissue Distribution

2004
Trend analysis of a database of intravenous pharmacokinetic parameters in humans for 670 drug compounds.
    Drug metabolism and disposition: the biological fate of chemicals, 2008, Volume: 36, Issue:7

    Topics: Blood Proteins; Half-Life; Humans; Hydrogen Bonding; Infusions, Intravenous; Pharmacokinetics; Protein Binding

2008
First-principle, structure-based prediction of hepatic metabolic clearance values in human.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:4

    Topics: Computational Biology; Drug Discovery; Hepatocytes; Humans; Hydrogen-Ion Concentration; Liver; Metabolic Clearance Rate; Models, Molecular; Pharmaceutical Preparations; Pharmacokinetics; Quantitative Structure-Activity Relationship; Sensitivity and Specificity; Software

2009
Physicochemical determinants of human renal clearance.
    Journal of medicinal chemistry, 2009, Aug-13, Volume: 52, Issue:15

    Topics: Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydrophobic and Hydrophilic Interactions; Kidney; Metabolic Clearance Rate; Molecular Weight

2009
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Physicochemical space for optimum oral bioavailability: contribution of human intestinal absorption and first-pass elimination.
    Journal of medicinal chemistry, 2010, Feb-11, Volume: 53, Issue:3

    Topics: Administration, Oral; Biological Availability; Humans; Intestinal Absorption; Pharmaceutical Preparations

2010
Multi-target spectral moment QSAR versus ANN for antiparasitic drugs against different parasite species.
    Bioorganic & medicinal chemistry, 2010, Mar-15, Volume: 18, Issue:6

    Topics: Antiparasitic Agents; Molecular Structure; Neural Networks, Computer; Parasitic Diseases; Quantitative Structure-Activity Relationship; Species Specificity; Thermodynamics

2010
Lack of effect of influenza vaccine on the pharmacokinetics of antipyrine, alprazolam, paracetamol (acetaminophen) and lorazepam.
    Clinical pharmacokinetics, 1989, Volume: 16, Issue:3

    Topics: Acetaminophen; Adult; Alprazolam; Antipyrine; Drug Administration Schedule; Drug Interactions; Female; Humans; Influenza Vaccines; Lorazepam; Male; Middle Aged; Time Factors

1989
Enterohepatic circulation of lorazepam and acetaminophen conjugates in ponies.
    The Journal of pharmacology and experimental therapeutics, 1988, Volume: 244, Issue:2

    Topics: Acetaminophen; Animals; Bile; Enterohepatic Circulation; Female; Glucuronates; Half-Life; Horses; In Vitro Techniques; Lorazepam; Sulfates

1988
Probenecid impairment of acetaminophen and lorazepam clearance: direct inhibition of ether glucuronide formation.
    The Journal of pharmacology and experimental therapeutics, 1985, Volume: 234, Issue:2

    Topics: Acetaminophen; Adult; Drug Interactions; Female; Glucuronates; Humans; Lorazepam; Male; Metabolic Clearance Rate; Middle Aged; Probenecid

1985
Enhanced glucuronide conjugation of drugs in obesity: studies of lorazepam, oxazepam, and acetaminophen.
    The Journal of laboratory and clinical medicine, 1983, Volume: 101, Issue:6

    Topics: Acetaminophen; Adult; Aged; Anti-Anxiety Agents; Female; Glucuronates; Humans; Lorazepam; Male; Middle Aged; Obesity; Oxazepam

1983
Differential effect of cimetidine on drug oxidation (antipyrine and diazepam) vs. conjugation (acetaminophen and lorazepam): prevention of acetaminophen toxicity by cimetidine.
    The Journal of pharmacology and experimental therapeutics, 1983, Volume: 224, Issue:3

    Topics: Acetaminophen; Adult; Animals; Antipyrine; Biotransformation; Cimetidine; Diazepam; Guanidines; Humans; Kinetics; Lethal Dose 50; Lorazepam; Male; Mice; Oxidation-Reduction

1983
Inhibition of acetaminophen and lorazepam glucuronidation in vitro by probenecid.
    Biopharmaceutics & drug disposition, 1993, Volume: 14, Issue:2

    Topics: Acetaminophen; Animals; Chromatography, High Pressure Liquid; Drug Interactions; Female; Humans; In Vitro Techniques; Lorazepam; Macaca; Male; Mice; Mice, Inbred Strains; Microsomes, Liver; Probenecid; Rats; Rats, Sprague-Dawley

1993
Use of single-dose activated charcoal among Canadian pediatric emergency physicians.
    Pediatric emergency care, 2006, Volume: 22, Issue:10

    Topics: Acetaminophen; Adolescent; Antidotes; Canada; Charcoal; Child, Preschool; Cross-Sectional Studies; Digoxin; Emergency Service, Hospital; Guideline Adherence; Health Care Surveys; Humans; Ibuprofen; Iron Compounds; Lorazepam; Male; Paroxetine; Poisoning; Time Factors

2006
Preparation and characterization of poly(methyltetradecylsiloxane) stationary phases immobilized by gamma radiation onto zirconized silica.
    Journal of chromatography. A, 2007, Jul-13, Volume: 1156, Issue:1-2

    Topics: Acetaminophen; Alprazolam; Benzene Derivatives; Chromatography, High Pressure Liquid; Ibuprofen; Lorazepam; Magnetic Resonance Spectroscopy; Silicon Dioxide; Siloxanes; Spectrophotometry, Infrared; Uracil; Zirconium

2007
Non-fatal ventricular dysrhythmias associated with severe salicylate toxicity.
    Clinical toxicology (Philadelphia, Pa.), 2008, Volume: 46, Issue:4

    Topics: Acetaminophen; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal; Arrhythmias, Cardiac; Aspirin; Female; Hemofiltration; Humans; Lorazepam; Middle Aged; Suicide, Attempted; Treatment Outcome; Ventricular Dysfunction

2008
Neuroleptic malignant syndrome induced by quetiapine overdose.
    British journal of hospital medicine (London, England : 2005), 2008, Volume: 69, Issue:3

    Topics: Acetaminophen; Antidotes; Antipsychotic Agents; Dibenzothiazepines; Drug Overdose; Female; Humans; Lorazepam; Middle Aged; Neuroleptic Malignant Syndrome; Quetiapine Fumarate; Treatment Outcome

2008
Comfort care kit: use of nonoral and nonparenteral rescue medications at home for terminally ill patients with swallowing difficulty.
    Journal of palliative medicine, 2014, Volume: 17, Issue:5

    Topics: Acetaminophen; Adjuvants, Anesthesia; Administration, Rectal; Administration, Sublingual; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Anxiety Agents; Antipsychotic Agents; Atropine; Caregivers; Deglutition Disorders; Female; Haloperidol; Home Care Services; Humans; Lorazepam; Male; Middle Aged; Morphine; Palliative Care; Pilot Projects; Singapore; Terminally Ill

2014
Comparison of constructed wetland performance coupled with aeration and tubesettler for pharmaceutical compound removal from hospital wastewater.
    Environmental research, 2023, 01-01, Volume: 216, Issue:Pt 1

    Topics: Acetaminophen; Animals; Carbamazepine; Ciprofloxacin; Erythromycin; Hospitals; Ibuprofen; Lorazepam; Pharmaceutical Preparations; Simvastatin; Waste Disposal, Fluid; Wastewater; Wetlands

2023