loratadine and pyrilamine

loratadine has been researched along with pyrilamine in 11 studies

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19902 (18.18)18.7374
1990's1 (9.09)18.2507
2000's7 (63.64)29.6817
2010's1 (9.09)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Caron, G; Ermondi, G1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM1
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Adams, Y; Ahenkorah, S; Laitinen, JT; Laitinen, T; Navia-Paldanius, D; Nevalainen, TJ; Parkkari, T; Patel, JZ; Savinainen, JR; Staszewski, M; Vaara, M; Walczyński, K1
Billah, MM; Chapman, RW; Egan, RW; Gilchrest, H; Kreutner, W; Piwinski, JJ; Sherwood, J; Siegel, MI; West, RE1
Ahn, HS; Barnett, A1
Ahn, HS; Barnett, A; Gulbenkian, A; Iorio, LC; Kreutner, W; Tozzi, S1
Anthes, JC; Billah, M; Eckel, S; Egan, RE; Gilchrest, H; Greenfeder, S; Hesk, D; Kreutner, W; Richard, C; West, RE; Williams, SM1
Fujii, Y; Harada, C; Hirai, T; Kamei, C; Tanaka, T1
Keseru, GM; Kiss, R; Kovári, Z1

Other Studies

11 other study(ies) available for loratadine and pyrilamine

ArticleYear
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4

2005
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Loratadine analogues as MAGL inhibitors.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Amidohydrolases; Dose-Response Relationship, Drug; Enzyme Inhibitors; Humans; Loratadine; Models, Molecular; Molecular Structure; Monoacylglycerol Lipases; Recombinant Proteins; Structure-Activity Relationship

2015
Sch 37370: a potent, orally active, dual antagonist of platelet-activating factor and histamine.
    The Journal of pharmacology and experimental therapeutics, 1990, Volume: 252, Issue:3

    Topics: Administration, Oral; Animals; Binding, Competitive; Brain; Bronchial Spasm; Female; Guinea Pigs; Histamine; Histamine Antagonists; Humans; Loratadine; Lung; Macaca fascicularis; Male; Mice; Piperidines; Platelet Activating Factor; Platelet Aggregation; Pyrilamine; Rats

1990
Selective displacement of [3H]mepyramine from peripheral vs. central nervous system receptors by loratadine, a non-sedating antihistamine.
    European journal of pharmacology, 1986, Aug-07, Volume: 127, Issue:1-2

    Topics: Aminopyridines; Animals; Binding, Competitive; Cerebral Cortex; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Kinetics; Loratadine; Lung; Male; Piperidines; Pyrilamine; Receptors, Cell Surface

1986
Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine.
    Agents and actions, 1984, Volume: 14, Issue:5-6

    Topics: Animals; Anticonvulsants; Autonomic Nervous System; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Dioxanes; Dogs; Female; Guinea Pigs; Histamine; Histamine Antagonists; Hypnotics and Sedatives; Lethal Dose 50; Loratadine; Male; Mice; Physostigmine; Piperidines; Pyrilamine; Rats; Saimiri; Time Factors

1984
Biochemical characterization of desloratadine, a potent antagonist of the human histamine H(1) receptor.
    European journal of pharmacology, 2002, Aug-09, Volume: 449, Issue:3

    Topics: Animals; Binding, Competitive; Calcium; CHO Cells; Cloning, Molecular; Cricetinae; DNA Primers; Female; Histamine H1 Antagonists; Humans; Kinetics; Loratadine; Oligonucleotides, Antisense; Pyrilamine; Receptors, Histamine H1

2002
Epileptogenic activity induced by histamine H(1) antagonists in amygdala-kindled rats.
    Brain research, 2003, Nov-21, Volume: 991, Issue:1-2

    Topics: Amygdala; Animals; Cetirizine; Diphenhydramine; Electroencephalography; Epilepsy; Histamine H1 Antagonists; Injections, Intraperitoneal; Ketotifen; Kindling, Neurologic; Loratadine; Male; Pyrilamine; Rats; Rats, Wistar

2003
Homology modelling and binding site mapping of the human histamine H1 receptor.
    European journal of medicinal chemistry, 2004, Volume: 39, Issue:11

    Topics: Algorithms; Amino Acid Sequence; Animals; Binding Sites; Cattle; Computer Simulation; Drug Interactions; Histamine Agonists; Histamine Antagonists; Humans; Loratadine; Models, Molecular; Molecular Sequence Data; Mutagenesis, Site-Directed; Protein Conformation; Pyrilamine; Receptors, Histamine H1; Rhodopsin; Sequence Homology, Amino Acid; Triprolidine

2004