loratadine and promethazine

loratadine has been researched along with promethazine in 17 studies

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's2 (11.76)18.2507
2000's6 (35.29)29.6817
2010's8 (47.06)24.3611
2020's1 (5.88)2.80

Authors

AuthorsStudies
Bleich, S; Gulbins, E; Kornhuber, J; Reichel, M; Terfloth, L; Tripal, P; Wiltfang, J1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Cuss, FM; Del Prado, M; Egan, RW; Hey, JA; Kreutner, W; Lin, CC; Sherwood, J1
Fairweather, DB; Hindmarch, I; Shamsi, Z; Stanley, N1
Hindmarch, I; Kimber, S; Shamsi, Z1
Hindmarch, I; Johnson, S; Kirkpatrick, T; Meadows, R; Shamsi, Z1
Baldauf, S1
Anoopkumar-Dukie, S; Grant, GD; Kavanagh, JJ1
Yanai, K1
Callaghan, JT; Duke, JD; Flockhart, DA; Hall, SD; Han, X; Jin, Y; Karnik, SD; Li, L; Li, X; Overhage, MJ; Quinney, SK; Strother, RM; Subhadarshini, A; Wang, Z1
Anoopkumar-Dukie, S; Grant, GD; Kavanagh, JJ; Naicker, P1
Anoopkumar-Dukie, S; Baumann-Birkbeck, L; Grant, GD; Kavanagh, JJ1

Reviews

1 review(s) available for loratadine and promethazine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

6 trial(s) available for loratadine and promethazine

ArticleYear
A double-blind, placebo-controlled investigation of the effects of fexofenadine, loratadine and promethazine on cognitive and psychomotor function.
    British journal of clinical pharmacology, 1999, Volume: 48, Issue:2

    Topics: Adult; Cognition; Cross-Over Studies; Double-Blind Method; Female; Flicker Fusion; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Loratadine; Male; Middle Aged; Promethazine; Psychomotor Performance; Reaction Time; Terfenadine; Wrist

1999
An investigation into the effects of cetirizine on cognitive function and psychomotor performance in healthy volunteers.
    European journal of clinical pharmacology, 2001, Volume: 56, Issue:12

    Topics: Adult; Cetirizine; Cognition; Cross-Over Studies; Double-Blind Method; Female; Flicker Fusion; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Promethazine; Psychomotor Performance; Reaction Time

2001
The acute and sub-chronic effects of levocetirizine, cetirizine, loratadine, promethazine and placebo on cognitive function, psychomotor performance, and weal and flare.
    Current medical research and opinion, 2001, Volume: 17, Issue:4

    Topics: Adult; Analysis of Variance; Area Under Curve; Cetirizine; Cognition; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Promethazine; Psychometrics; Psychomotor Performance; Reaction Time; Skin Tests

2001
Low dosage promethazine and loratadine negatively affect neuromotor function.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2012, Volume: 123, Issue:4

    Topics: Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Heart Rate; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Motor Neurons; Movement; Promethazine; Reaction Time; Sleep Stages; Tremor; Young Adult

2012
The effects of antihistamines with varying anticholinergic properties on voluntary and involuntary movement.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2013, Volume: 124, Issue:9

    Topics: Adult; Cholinergic Antagonists; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Promethazine; Reaction Time; Sleep Stages; Terfenadine; Tremor; Young Adult

2013
Drowsiness and motor responses to consecutive daily doses of promethazine and loratadine.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2014, Volume: 125, Issue:12

    Topics: Adult; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Promethazine; Reaction Time; Sleep Stages; Tremor; Young Adult

2014

Other Studies

10 other study(ies) available for loratadine and promethazine

ArticleYear
Identification of new functional inhibitors of acid sphingomyelinase using a structure-property-activity relation model.
    Journal of medicinal chemistry, 2008, Jan-24, Volume: 51, Issue:2

    Topics: Algorithms; Animals; Cell Line; Cell Line, Tumor; Chemical Phenomena; Chemistry, Physical; Enzyme Inhibitors; Humans; Hydrogen-Ion Concentration; Molecular Conformation; Quantitative Structure-Activity Relationship; Rats; Sphingomyelin Phosphodiesterase

2008
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Antihistamine activity, central nervous system and cardiovascular profiles of histamine H1 antagonists: comparative studies with loratadine, terfenadine and sedating antihistamines in guinea-pigs.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1995, Volume: 25, Issue:10

    Topics: Animals; Cardiovascular System; Central Nervous System; Diphenhydramine; Electrocardiography; Electroencephalography; Guinea Pigs; Histamine H1 Antagonists; Hypnotics and Sedatives; Loratadine; Male; Promethazine; Quinidine; Terfenadine

1995
Vanished behind the counter. Starting this week, you'll need help buying your claritin and nyquil.
    U.S. news & world report, 2006, Oct-02, Volume: 141, Issue:12

    Topics: Acetaminophen; Dextromethorphan; Doxylamine; Drug Combinations; Ephedrine; Humans; Legislation, Drug; Loratadine; Methamphetamine; Nasal Decongestants; Promethazine; Pseudoephedrine; United States

2006
Anticholinergic activity of antihistamines.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2012, Volume: 123, Issue:4

    Topics: Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Motor Neurons; Movement; Promethazine

2012
Literature based drug interaction prediction with clinical assessment using electronic medical records: novel myopathy associated drug interactions.
    PLoS computational biology, 2012, Volume: 8, Issue:8

    Topics: Alprazolam; Databases, Factual; Drug Interactions; Duloxetine Hydrochloride; Electronic Health Records; Humans; Indoles; Loratadine; Muscular Diseases; Promethazine; Simvastatin; Thiophenes

2012