loratadine and mizolastine

loratadine has been researched along with mizolastine in 23 studies

Research

Studies (23)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (26.09)18.2507
2000's13 (56.52)29.6817
2010's4 (17.39)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Keserü, GM1
Nagashima, R; Nishikawa, T; Tobita, M1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM1
Jia, L; Sun, H1
Caron, G; Ermondi, G; Visentin, S1
Sen, S; Sinha, N1
O'Hanlon, JF; Ramaekers, JG1
Cabanis, MJ; Caplain, H; Chaufour, S; Rosenzweig, P; Thebault, JJ; Ulliac, N1
Bellioni, P; Carraro, A; Catalano, B; Cervellera, G; Filiaci, F; Mira, E1
Dubertret, L; Murrieta Aguttes, M; Tonet, J1
Mattila, MJ; Paakkari, I1
Collart, P; Nicolas, JM; Roba, J; Whomsley, R1
DeVos, C; Grant, JA; Moulaert, B; Riethuisen, JM1
Antosova, E; Bachert, C; Frèche, C; Goos, M; Gracia, FD; Hide, D; Horak, F; Horvath, A; Leynadier, F; Soussen, PB; Verrecchia, M1
Benedetti, MS; Diquet, B; Molimard, M1
Fang, Q; Li, H; Wang, R; Yin, J; Zhang, H1
Wang, RQ; Zhang, HY1
Chen, B; He, PP; Wang, DB; Wang, Y; Xia, Q; Yan, KL; Yang, S; Zhang, SQ; Zhang, XJ; Zhu, QX1
Chen, M; Chen, W; Chen, X; Guo, A; He, Y; Li, J; Liu, Z; Su, J; Wen, S; Yan, S; Zhang, C; Zhang, J; Zhao, Y; Zhou, H; Zhu, W1
Chen, M; Chen, W; Chen, X; Guo, A; He, Y; Li, J; Liu, Z; Su, J; Wen, S; Yan, S; Zeng, W; Zhang, C; Zhang, J; Zhao, Y; Zhou, H; Zhu, W1
Chen, M; Chen, W; Chen, X; Li, F; Li, J; Li, Q; Liu, Z; Peng, C; Su, J; Yan, S; Zhang, J; Zhang, W; Zhu, W1

Reviews

2 review(s) available for loratadine and mizolastine

ArticleYear
Variations among non-sedating antihistamines: are there real differences?
    European journal of clinical pharmacology, 1999, Volume: 55, Issue:2

    Topics: Astemizole; Benzimidazoles; Butyrophenones; Central Nervous System; Cetirizine; Drug Interactions; Heart; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Loratadine; Piperidines; Potassium Channel Blockers; Terfenadine; Triprolidine

1999
Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:4

    Topics: Absorption; Animals; Area Under Curve; Benzimidazoles; Biological Availability; Cetirizine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Metabolic Clearance Rate; Piperazines; Terfenadine; Tissue Distribution

2004

Trials

9 trial(s) available for loratadine and mizolastine

ArticleYear
Antihistamine effects on actual driving performance in a standard test: a summary of Dutch experience, 1989-94.
    Allergy, 1995, Volume: 50, Issue:3

    Topics: Automobile Driving; Benzimidazoles; Butyrophenones; Cetirizine; Clemastine; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Loratadine; Netherlands; Piperidines; Psychomotor Performance; Terfenadine; Triprolidine

1995
Comparative wheal and flare study of mizolastine vs terfenadine, cetirizine, loratadine and placebo in healthy volunteers.
    British journal of clinical pharmacology, 1995, Volume: 40, Issue:5

    Topics: Adult; Benzimidazoles; Cetirizine; Cross-Over Studies; Double-Blind Method; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Loratadine; Male; Terfenadine

1995
Comparison of mizolastine with loratadine in the treatment of perennial allergic rhinitis.
    Rhinology, 1996, Volume: 34, Issue:2

    Topics: Adult; Benzimidazoles; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Rhinitis, Allergic, Perennial; Time Factors

1996
Efficacy and safety of mizolastine 10 mg in a placebo-controlled comparison with loratadine in chronic idiopathic urticaria: results of the MILOR Study.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 1999, Volume: 12, Issue:1

    Topics: Adult; Analysis of Variance; Appendicitis; Benzimidazoles; Chronic Disease; Double-Blind Method; Electrocardiography; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Patient Dropouts; Pruritus; Severity of Illness Index; Treatment Outcome; Urticaria; Vasculitis

1999
A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 88, Issue:2

    Topics: Adult; Benzimidazoles; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Piperidines; Terfenadine; Treatment Outcome; Urticaria

2002
Mizolastine provides effective symptom relief in patients suffering from perennial allergic rhinitis: a double-blind, placebo-controlled study versus loratadine.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 89, Issue:3

    Topics: Adolescent; Adult; Anti-Allergic Agents; Benzimidazoles; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Rhinitis, Allergic, Perennial; Treatment Outcome

2002
[Clinical examination of mizolastine in the seasonal allergic rhinitis].
    Lin chuang er bi yan hou ke za zhi = Journal of clinical otorhinolaryngology, 2004, Volume: 18, Issue:8

    Topics: Adolescent; Adult; Aged; Benzimidazoles; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Seasonal

2004
[Comparative activity of antihistamines on area under dose-response curve from histamine-induced wheal and flare responses in human skin].
    Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae, 2004, Volume: 26, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Area Under Curve; Benzimidazoles; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests; Time Factors; Urticaria

2004
Association of FCER1A genetic polymorphisms with risk for chronic spontaneous urticaria and efficacy of nonsedating H1-antihistamines in Chinese patients.
    Archives of dermatological research, 2015, Volume: 307, Issue:2

    Topics: Adult; Asian People; Benzimidazoles; China; Female; Genotyping Techniques; Histamine H1 Antagonists, Non-Sedating; Humans; Immunoglobulin E; Loratadine; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Receptors, IgE; Terfenadine; Urticaria; Young Adult

2015

Other Studies

12 other study(ies) available for loratadine and mizolastine

ArticleYear
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
    Bioorganic & medicinal chemistry letters, 2003, Aug-18, Volume: 13, Issue:16

    Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2003
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4

2005
Support vector machines classification of hERG liabilities based on atom types.
    Bioorganic & medicinal chemistry, 2008, Jun-01, Volume: 16, Issue:11

    Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve

2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship

2009
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
In vitro inhibition of human liver drug metabolizing enzymes by second generation antihistamines.
    Chemico-biological interactions, 1999, Nov-15, Volume: 123, Issue:1

    Topics: Astemizole; Benzimidazoles; Cetirizine; Cytochrome P-450 Enzyme Inhibitors; Dimethyl Sulfoxide; Enzyme Inhibitors; Glucuronosyltransferase; Histamine H1 Antagonists; Humans; Isoenzymes; Kinetics; Loratadine; Microsomes, Liver; Terfenadine

1999
[Antihistaminics. Side effects also after raising dosage at the placebo level].
    MMW Fortschritte der Medizin, 2003, May-29, Volume: 145, Issue:22

    Topics: Anti-Allergic Agents; Benzimidazoles; Butyrophenones; Cetirizine; Double-Blind Method; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Meta-Analysis as Topic; Piperidines; Placebos; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal

2003
The effect of mizolastine on expression of vascular endothelial cell growth factor, tumour necrosis factor-alpha and keratinocyte-derived chemokine in murine mast cells, compared with dexamethasone and loratadine.
    Clinical and experimental dermatology, 2005, Volume: 30, Issue:2

    Topics: Angiogenesis Inducing Agents; Animals; Anti-Inflammatory Agents; Benzimidazoles; Cells, Cultured; Chemokine CXCL1; Chemokines; Chemokines, CXC; Cytokines; Dexamethasone; Dose-Response Relationship, Drug; Gene Expression Regulation; Histamine H1 Antagonists; Loratadine; Mast Cells; Mice; Receptors, IgE; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Tumor Necrosis Factor-alpha; Vascular Endothelial Growth Factor A

2005
Influence of component 5a receptor 1 (C5AR1) -1330T/G polymorphism on nonsedating H1-antihistamines therapy in Chinese patients with chronic spontaneous urticaria.
    Journal of dermatological science, 2014, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Aged; Asian People; Benzimidazoles; Case-Control Studies; China; Chronic Disease; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Middle Aged; Polymorphism, Single Nucleotide; Prospective Studies; Receptor, Anaphylatoxin C5a; Risk Factors; Treatment Outcome; Urticaria; Young Adult

2014
C-reactive protein (CRP) rs3093059C predicts poor mizolastine response in chronic spontaneous urticaria patients with elevated serum CRP level.
    Experimental dermatology, 2019, Volume: 28, Issue:3

    Topics: Adolescent; Adult; Aged; Animals; Benzimidazoles; C-Reactive Protein; China; Chronic Disease; Chronic Urticaria; Female; Gene Expression; Genotype; HEK293 Cells; Histamine H1 Antagonists; Humans; Interleukin-6; Loratadine; Male; Middle Aged; Polymorphism, Single Nucleotide; Rats; Treatment Outcome; Tumor Necrosis Factor-alpha; Young Adult

2019