loratadine and hydroxyzine

loratadine has been researched along with hydroxyzine in 31 studies

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-19901 (3.23)18.7374
1990's19 (61.29)18.2507
2000's6 (19.35)29.6817
2010's5 (16.13)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Jolliet, P; Morin, C; Morin, D; Pagliara, A; Rihoux, JP; Testa, B; Tillement, JP; Urien, S1
Caron, G; Ermondi, G1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM1
Glen, RC; Lowe, R; Mitchell, JB1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Barkley, AS; Millard, LG; Shall, L; Thompson, DA1
O'Hanlon, JF; Ramaekers, JG; Uiterwijk, MM1
Bernstein, DI; Cuss, F; Danzig, MR; Fox, RW; Garvin, PR; Grabiec, SV; Honsinger, RW; Kalivas, JT; Katz, HI; Monroe, EW1
Hill, S; Lever, LR; Marks, R; Rosenberg, R; Thompson, D1
Fletcher, MP; Ryhal, BT1
Soter, NA1
Gillardin, JM; Gommeren, W; Janssen, PA; Janssen, PF; Leysen, JE; Sanz, G; Schotte, A1
Humphreys, F; Hunter, JA1
Coulie, P; Ghys, L; Rihoux, JP1
McMillan, JL; Simons, FE; Simons, KJ1
Woodward, JK1
Kaiser, HB1
Simons, FE1
Herakleous, M; Kontou-Fili, K; Paleologos, G1
Arron, RJ; Bogdanovic, RP; Brandes, LJ; Fang, W; LaBella, FS; Queen, GM; Stein, DA; Tong, J; Warrington, RC; Zaborniak, CL1
Robinson, A1
Woosley, RL1
Annunziato, L; Castaldo, P; Fresi, A; Giorgio, G; Pannaccione, A; Rosati, B; Secondo, A; Taglialatela, M; Wanke, E1
dos Santos, RV; Lima, HC; Magerl, M; Mlynek, A1
Bagad, AS; Bahekar, PC; Chidrewar, GU; Mandhane, SN; Mehetre, SV; Pawar, CA; Rajamannar, T; Rao, CT; Shah, JH1
Bennett, C; Carter, B; Cohen, SN; Sharma, M1
Kannappan, V; Kanthiah, S1

Reviews

7 review(s) available for loratadine and hydroxyzine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
The second-generation antihistamines. What makes them different?
    Postgraduate medicine, 1991, May-01, Volume: 89, Issue:6

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Blood-Brain Barrier; Brain; Cetirizine; Cyproheptadine; Education, Medical, Continuing; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity; Loratadine; Terfenadine

1991
H1-receptor antagonist treatment of seasonal allergic rhinitis.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Clemastine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Ketotifen; Loratadine; Rhinitis, Allergic, Seasonal; Terfenadine

1990
Recent advances in H1-receptor antagonist treatment.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:6 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Receptors, Histamine H1; Rhinitis, Allergic, Perennial; Terfenadine; Urticaria

1990
Three new non-sedative antihistamines: worth keeping an eye open for.
    Drug and therapeutics bulletin, 1990, May-14, Volume: 28, Issue:10

    Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Rhinitis, Allergic, Seasonal; Triprolidine; Urticaria

1990
Cardiac actions of antihistamines.
    Annual review of pharmacology and toxicology, 1996, Volume: 36

    Topics: Animals; Astemizole; Cetirizine; Diphenhydramine; Drug Interactions; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Terfenadine; Torsades de Pointes

1996
H1-antihistamines for chronic spontaneous urticaria.
    The Cochrane database of systematic reviews, 2014, Nov-14, Issue:11

    Topics: Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Randomized Controlled Trials as Topic; Urticaria

2014

Trials

9 trial(s) available for loratadine and hydroxyzine

ArticleYear
Comparative inhibition profiles of three non-sedating antihistamines assessed by an extended Lewis model.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 1992, Volume: 22, Issue:7

    Topics: Adult; Analysis of Variance; Cetirizine; Cyproheptadine; Female; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Injections, Intradermal; Loratadine; Male; Models, Biological; Single-Blind Method; Skin; Skin Tests; Terfenadine

1992
Effects of loratadine and cetirizine on actual driving and psychometric test performance, and EEG during driving.
    European journal of clinical pharmacology, 1992, Volume: 42, Issue:4

    Topics: Adult; Automobile Driving; Cetirizine; Cyproheptadine; Double-Blind Method; Electroencephalography; Ethanol; Female; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Psychological Tests; Psychometrics; Psychomotor Performance

1992
Relative efficacy and safety of loratadine, hydroxyzine, and placebo in chronic idiopathic urticaria.
    Arzneimittel-Forschung, 1992, Volume: 42, Issue:9

    Topics: Adolescent; Adult; Aged; Chronic Disease; Double-Blind Method; Humans; Hydroxyzine; Loratadine; Middle Aged; Pruritus; Urticaria

1992
Effects of cetirizine, loratadine and terfenadine on histamine weal and flare reactions.
    Skin pharmacology : the official journal of the Skin Pharmacology Society, 1992, Volume: 5, Issue:1

    Topics: Administration, Oral; Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Erythema; Female; Histamine; Histamine Antagonists; Humans; Hydroxyzine; Loratadine; Male; Middle Aged; Random Allocation; Skin; Terfenadine

1992
The effects of astemizole, cetirizine and loratadine on the time course of weal and flare reactions to histamine, codeine and antigen.
    The British journal of dermatology, 1991, Volume: 125, Issue:4

    Topics: Adult; Animals; Antigens; Astemizole; Cetirizine; Codeine; Cyproheptadine; Dermatitis, Contact; Dust; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Middle Aged; Mites; Skin; Time Factors

1991
Compared peripheral H1 inhibiting effects of cetirizine 2 HCl and loratadine.
    Annals of allergy, 1990, Volume: 65, Issue:2

    Topics: Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Drug Hypersensitivity; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Hypnotics and Sedatives; Loratadine; Male; Middle Aged; Placebos; Randomized Controlled Trials as Topic

1990
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:4 Pt 1

    Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Placebos; Skin Tests; Terfenadine; Time Factors; Urticaria

1990
Suppression of histamine-induced skin reactions by loratadine and cetirizine diHCl.
    European journal of clinical pharmacology, 1989, Volume: 36, Issue:6

    Topics: Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Middle Aged; Random Allocation; Skin

1989
Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 102, Issue:6

    Topics: Adult; Allergens; Animals; Dermatophagoides pteronyssinus; Dibenzazepines; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine; Imidazoles; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome; Urticaria

2009

Other Studies

15 other study(ies) available for loratadine and hydroxyzine

ArticleYear
Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist.
    Journal of medicinal chemistry, 1998, Mar-12, Volume: 41, Issue:6

    Topics: Alkanes; Animals; Biological Transport; Blood Proteins; Brain; Cetirizine; Histamine H1 Antagonists; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyzine; Isomerism; Models, Molecular; Molecular Conformation; Octanols; Rats; Water

1998
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
    Journal of medicinal chemistry, 2005, May-05, Volume: 48, Issue:9

    Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water

2005
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
    Toxicology mechanisms and methods, 2008, Volume: 18, Issue:2-3

    Topics:

2008
Predicting phospholipidosis using machine learning.
    Molecular pharmaceutics, 2010, Oct-04, Volume: 7, Issue:5

    Topics: Animals; Artificial Intelligence; Databases, Factual; Drug Discovery; Humans; Lipidoses; Models, Biological; Phospholipids; Support Vector Machine

2010
Treatment of urticaria and angioedema: low-sedating H1-type antihistamines.
    Journal of the American Academy of Dermatology, 1991, Volume: 24, Issue:6 Pt 2

    Topics: Angioedema; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Terfenadine; Urticaria

1991
[Non-sedative antihistaminics and binding to central and peripheral H1 histamine receptors].
    Allergie et immunologie, 1991, Volume: 23, Issue:2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cerebellum; Cetirizine; Cyproheptadine; Histamine H1 Antagonists; Hydroxyzine; Kinetics; Loratadine; Lung; Organ Specificity; Protein Binding; Receptors, Histamine H1; Terfenadine

1991
Pharmacology of antihistamines.
    The Journal of allergy and clinical immunology, 1990, Volume: 86, Issue:4 Pt 2

    Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Cyproheptadine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Terfenadine; Time Factors

1990
Enhanced cancer growth in mice administered daily human-equivalent doses of some H1-antihistamines: predictive in vitro correlates.
    Journal of the National Cancer Institute, 1994, May-18, Volume: 86, Issue:10

    Topics: Animals; Astemizole; Carcinogens; Cetirizine; Doxylamine; Female; Histamine H1 Antagonists; Hydroxyzine; Loratadine; Melanoma, Experimental; Mice; Mice, Inbred C3H; Mice, Inbred C57BL; Rats; Rats, Sprague-Dawley

1994
More questions than answers: antihistamines' link to cancer.
    CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne, 1994, Sep-15, Volume: 151, Issue:6

    Topics: Animals; Astemizole; Canada; Dose-Response Relationship, Drug; Drug Industry; Fibrosarcoma; Histamine Antagonists; Histamine H1 Antagonists; Hydroxyzine; Loratadine; Melanoma, Experimental; Mice; Phenyl Ethers; Tamoxifen; United States; United States Food and Drug Administration

1994
Ambivalent antihistamines.
    Environmental health perspectives, 1994, Volume: 102, Issue:11

    Topics: Animals; Astemizole; Carcinogens; Histamine H1 Antagonists; Hydroxyzine; Loratadine; Mice; Neoplasms, Experimental

1994
Inhibition of depolarization-induced [3H]noradrenaline release from SH-SY5Y human neuroblastoma cells by some second-generation H(1) receptor antagonists through blockade of store-operated Ca(2+) channels (SOCs).
    Biochemical pharmacology, 2001, Nov-01, Volume: 62, Issue:9

    Topics: Astemizole; Calcium; Calcium Channel Blockers; Calcium Channels; Cation Transport Proteins; Cetirizine; DNA-Binding Proteins; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Neuroblastoma; Norepinephrine; Potassium Channels; Potassium Channels, Voltage-Gated; Receptors, Histamine H1; Terfenadine; Trans-Activators; Transcriptional Regulator ERG; Tritium; Tumor Cells, Cultured

2001
Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.
    International archives of allergy and immunology, 2010, Volume: 151, Issue:1

    Topics: Acetates; Alcohols; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Cetirizine; Drug Interactions; Female; Guinea Pigs; Histamine H1 Antagonists, Non-Sedating; Hydroxyzine; Hypersensitivity; Immunoglobulin G; Interleukin-4; Leukocytes; Loratadine; Male; Mice; Mice, Inbred BALB C; Nasal Lavage Fluid; Nasal Mucosa; Pentobarbital; Piperazines; Sneezing; Terfenadine

2010
D-Optimal mixture design optimization of an HPLC method for simultaneous determination of commonly used antihistaminic parent molecules and their active metabolites in human serum and urine.
    Biomedical chromatography : BMC, 2017, Volume: 31, Issue:8

    Topics: Anti-Allergic Agents; Chromatography, High Pressure Liquid; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Limit of Detection; Loratadine; Solid Phase Extraction; Terfenadine

2017