loratadine has been researched along with histamine in 82 studies
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (6.10) | 18.7374 |
1990's | 29 (35.37) | 18.2507 |
2000's | 34 (41.46) | 29.6817 |
2010's | 12 (14.63) | 24.3611 |
2020's | 2 (2.44) | 2.80 |
Authors | Studies |
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Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM | 1 |
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM | 1 |
Choi, SS; Contrera, JF; Hastings, KL; Kruhlak, NL; Sancilio, LF; Weaver, JL; Willard, JM | 1 |
Brodsky, JL; Chiang, A; Chung, WJ; Denny, RA; Goeckeler-Fried, JL; Havasi, V; Hong, JS; Keeton, AB; Mazur, M; Piazza, GA; Plyler, ZE; Rasmussen, L; Rowe, SM; Sorscher, EJ; Weissman, AM; White, EL | 1 |
Coussement, C; Ghys, L; Rihoux, JP; Van Neste, D | 1 |
Cieślewicz, G; Gondorowicz, K; Grzelewska-Rzymowska, I; Rozniecki, J; Wojciechowska, B | 1 |
Juhlin, L; Pihl-Lundin, I | 1 |
Naclerio, RM | 1 |
Hill, S; Lever, LR; Marks, R; Rosenberg, R; Thompson, D | 1 |
Humphreys, F; Hunter, JA | 1 |
Chapman, RW; Egan, RW; Kreutner, W; Mauser, PJ | 1 |
Coulie, P; Ghys, L; Rihoux, JP | 1 |
Bousquet, J; Chanal, I; Lemonier, C; Michel, FB; Skassa-Brociek, W | 1 |
McMillan, JL; Simons, FE; Simons, KJ | 1 |
Hammarlund, A; Olsson, P; Pipkorn, U | 1 |
Holgate, ST; Town, GI | 1 |
Billah, MM; Chapman, RW; Egan, RW; Gilchrest, H; Kreutner, W; Piwinski, JJ; Sherwood, J; Siegel, MI; West, RE | 1 |
Dirksen, A; Engel, T; Frølund, L; Heinig, JH; Svendsen, UG; Weeke, B | 1 |
Herakleous, M; Kontou-Fili, K; Paleologos, G | 1 |
Gural, RP; Herron, J; Kassem, N; Roman, IJ | 1 |
Dyer, JG; Gural, R; Kassem, N; Robillard, N; Roman, I | 1 |
Ahn, HS; Barnett, A; Gulbenkian, A; Iorio, LC; Kreutner, W; Tozzi, S | 1 |
Buko, Z; Chyrek-Borowska, S; Michalska, I; Siergiejko, Z; Swiderska, M | 1 |
Cieślewicz, G; Gondorowicz, K; Grzelewska-Rzymowska, I; Rozniecki, J | 1 |
Bousquet, J; Campbell, AM; Crampette, L; Czarlewski, W; Mondain, M; Sauvère, G; Vignola, AM | 1 |
Chapman, RW; Hutt, DA; Kreutner, W; Morton, JB; Sherwood, JE | 1 |
Cartier, A; Ghezzo, H; L'Archevêque, J; Labrecque, M; Malo, JL; Trudeau, C | 1 |
Akagi, M; Izushi, K; Kamei, C; Mio, M; Nakamura, S; Tasaka, K; Yoshida, T | 1 |
Benabdesselam, O; Braun, JJ; Frossard, N; Glasser, N; Lacronique, J; Melac, M; Pauli, G | 1 |
Czarlewski, W; Gosset, P; Lassalle, P; Molet, S; Tonnel, AB | 1 |
Canonica, GW; Ciprandi, G; Danzig, M; Passalacqua, G; Pronzato, C; Ricca, V | 1 |
Bennett, AR; Church, MK; Clough, GF | 1 |
Bousquet, J; Cougnard, J; Czarlewski, W; Danzig, M; Michel, FB | 1 |
Benabdesselam, O; Frossard, N; Glasser, N; Lacronique, J; Melac, M; Pauli, G | 1 |
Bousquet, J; Demoly, P; Harris, AG; Michel, FB; Persi, L; Tisserand, B | 1 |
Danielson, L; DeVos, C; Grant, JA; Rihoux, JP | 1 |
Baroody, FM; Blair, C; deTineo, M; Gungor, A; Haney, L; Naclerio, RM | 1 |
Altintaş, L; Apaydýn, R; Bayramgürler, D; Bilen, N; Dökmeci, S; Sal, G; Utkan, T | 1 |
Abdelaziz, MM; Devalia, JL; Khair, OA | 1 |
Boutsiouki, P; Church, MK; Clough, GF | 1 |
DeVos, C; Grant, JA; Moulaert, B; Riethuisen, JM | 1 |
Anderson, SD; Brannan, JD | 1 |
Furue, M; Koga, T; Morita, K; Moroi, Y; Urabe, K | 1 |
Gras, J; Llenas, J; Llupià, J | 1 |
Boyce, M; Carey, W; Luria, X; Warrington, S | 1 |
Hill, SL; Krouse, JH | 1 |
Boutsiouki, P; Church, MK; Clough, GF; Denham, KJ | 1 |
Frossard, N; Melac, M; Pauli, G; Purohit, A | 1 |
Anthes, JC; Harris, AG; Kreutner, W; West, RE; Wu, RL | 1 |
Riechelmann, H | 1 |
Wang, RQ; Zhang, HY | 1 |
Fujii, Y; Hossen, MA; Kamei, C; Ogawa, M; Takubo, M; Tsumuro, T | 1 |
Kirtsreesakul, V; Klemens, JJ; Luxameechanporn, T; Naclerio, RM | 1 |
Górski, P; Kuna, P; Kupczyk, M; Kupryś, I | 1 |
Drábiková, K; Jancinová, V; Macicková, T; Nosál, R; Pecivová, J | 1 |
Chen, GG; Leung, PC; van Hasselt, CA; Wang, LH; Wong, YO; Woo, JK; Zhao, Y | 1 |
Arimura, A; Asakawa, M; Deguchi, M; Hikita, I; Hirasawa, T; Horikawa, T; Matsutani, T; Oku, H; Yoshioka, T | 1 |
Bachvarova, A; Bocsan, C; Church, MK; Dimitrov, V; Dumitrascu, D; Popov, TA | 1 |
Drábiková, K; Holománová, D; Jancinová, V; Macicková, T; Nosál', R; Pecivová, J | 1 |
Kruszewski, J; Kłos, K; Sułek, K | 1 |
Kruszewski, J; Kruszewski, R; Kłos, K; Sułek, K | 1 |
Antonijoan, RM; Barbanoj, MJ; Esbri, R; Fortea, J; García-Gea, C; Puntes, M; Valle, M | 1 |
Antonijoan, R; Barbanoj, MJ; Esbrí, R; Fortea, J; García-Gea, C; Pérez, J; Puntes, M; Serra, C | 1 |
Drábikova, K; Holománová, D; Jancinová, V; Macicková, T; Nosál, R; Pecivová, J | 1 |
Devillier, P | 1 |
Baroody, FM; Detineo, M; Mucha, SM; Naclerio, RM | 1 |
Ikezawa, Z; Inomata, N; Tatewaki, S | 1 |
Goulas, A; Kalokasidis, K; Kokkas, B; Mirtsou, V; Molyva, D | 1 |
dos Santos, RV; Lima, HC; Magerl, M; Mlynek, A | 1 |
deRossi, T; Hagel, A; Hahn, EG; Konturek, P; Kressel, J; Nägel, A; Raithel, M; Stengel, Ch; Zopf, Y | 1 |
Hunter, JC; Jia, Y; Jimenez, J; Lieber, G; McLeod, RL | 1 |
Chen, LG; Lin, Y; Liu, DK; Si-Ma, LF; Wang, DH; Wang, J; Wang, Y | 1 |
Chen, LG; Li, L; Lin, Y; Sima, LF; Wang, DH; Wang, Y | 1 |
Church, MK; Maurer, M | 1 |
Bayramgürler, D; Bilen, N; Bulca, S; Kıran, R; Odyakmaz Demirsoy, E; Sikar Aktürk, A; Yavuz, M | 1 |
Chen, M; He, G; Jie, Q; Kodithuwakku, ND; Wu, Y; Xu, S; Yuan, X | 1 |
Chen, M; He, G; Jie, Q; Wu, Y; Xu, S; Zhou, P | 1 |
Bosma, R; Leurs, R; Moritani, R; Vischer, HF | 1 |
Antonijoan, R; Campo, C; Coimbra, J; García-Gea, C; Gich, I; Labeaga, L; Puntes, M; Valiente, R | 1 |
Booncong, P; Dechatiwongse Na Ayudhya, T; Jiratchariyakul, W; Koontongkaew, S; Kulalert, P; Poachanukoon, O; Soawakontha, R; Tanticharoenwiwat, P | 1 |
Athari, SS; Hassanpour, F; Mehrabi Nasab, E; Shen, Y | 1 |
Gotoh, M; Hosomi, N; Kaminuma, O; Miura, K; Miura, S; Mori, A; Ogata, S; Uda, N; Yamasaki, N | 1 |
3 review(s) available for loratadine and histamine
Article | Year |
---|---|
Exercise-induced asthma: is there still a case for histamine?
Topics: Asthma, Exercise-Induced; Histamine; Histamine H1 Antagonists; Humans; Indoles; Leukotriene Antagonists; Loratadine; Phenylcarbamates; Sulfonamides; Tosyl Compounds | 2002 |
[Oral second generation antihistamines in allergic rhinitis].
Topics: Administration, Oral; Adult; Anti-Allergic Agents; Cetirizine; Child; Conjunctivitis, Allergic; Controlled Clinical Trials as Topic; Female; Histamine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity, Immediate; Loratadine; Male; Nasal Mucosa; Pregnancy; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Rhinitis, Allergic, Seasonal; Time Factors | 2005 |
H(1)-antihistamines and urticaria: how can we predict the best drug for our patient?
Topics: Anti-Allergic Agents; Cetirizine; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Predictive Value of Tests; Skin Tests; Terfenadine; Urticaria | 2012 |
45 trial(s) available for loratadine and histamine
Article | Year |
---|---|
Agonist-antagonist interactions in the skin: comparison of effects of loratadine and cetirizine on skin vascular responses to prick tests with histamine and substance P.
Topics: Adult; Blood Flow Velocity; Cetirizine; Female; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Loratadine; Male; Middle Aged; Skin; Skin Tests; Substance P | 1992 |
Inhibition of mediator release during the early reaction to antigen.
Topics: Albumins; Antigens; Cetirizine; Esterases; Histamine; Humans; Kinins; Loratadine; Nasal Mucosa; Nasal Provocation Tests; Terfenadine; Tosylarginine Methyl Ester | 1992 |
Effects of cetirizine, loratadine and terfenadine on histamine weal and flare reactions.
Topics: Administration, Oral; Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Erythema; Female; Histamine; Histamine Antagonists; Humans; Hydroxyzine; Loratadine; Male; Middle Aged; Random Allocation; Skin; Terfenadine | 1992 |
The effects of astemizole, cetirizine and loratadine on the time course of weal and flare reactions to histamine, codeine and antigen.
Topics: Adult; Animals; Antigens; Astemizole; Cetirizine; Codeine; Cyproheptadine; Dermatitis, Contact; Dust; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Middle Aged; Mites; Skin; Time Factors | 1991 |
Compared peripheral H1 inhibiting effects of cetirizine 2 HCl and loratadine.
Topics: Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Drug Hypersensitivity; Female; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Humans; Hydroxyzine; Hypersensitivity, Immediate; Hypnotics and Sedatives; Loratadine; Male; Middle Aged; Placebos; Randomized Controlled Trials as Topic | 1990 |
Lack of subsensitivity to loratadine during long-term dosing during 12 weeks.
Topics: Adult; Allergens; Cyproheptadine; Double-Blind Method; Drug Tolerance; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Skin Tests | 1990 |
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects.
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Placebos; Skin Tests; Terfenadine; Time Factors; Urticaria | 1990 |
Blood flow in histamine- and allergen-induced weal and flare responses, effects of an H1 antagonist, alpha-adrenoceptor agonist and a topical glucocorticoid.
Topics: Administration, Topical; Adult; Allergens; Antigen-Antibody Reactions; Betamethasone; Clobetasol; Cyproheptadine; Double-Blind Method; Ephedrine; Female; Histamine; Histamine Antagonists; Humans; Lasers; Loratadine; Male; Random Allocation; Regional Blood Flow; Skin; Skin Tests | 1990 |
Comparison of the effect of loratadine on the airway and skin responses to histamine, methacholine, and allergen in subjects with asthma.
Topics: Adult; Allergens; Asthma; Bronchi; Bronchial Provocation Tests; Cyproheptadine; Female; Histamine; Histamine Antagonists; Humans; Loratadine; Methacholine Chloride; Middle Aged; Skin; Skin Tests | 1990 |
Effect of a non-sedative antihistaminic (loratadine) in moderate asthma. A double-blind controlled clinical crossover-trial.
Topics: Adult; Asthma; Bronchi; Clinical Trials as Topic; Cyproheptadine; Double-Blind Method; Female; Forced Expiratory Volume; Histamine; Histamine Antagonists; Humans; Loratadine; Male; Middle Aged; Peak Expiratory Flow Rate | 1989 |
Suppression of histamine-induced skin reactions by loratadine and cetirizine diHCl.
Topics: Adult; Cetirizine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Middle Aged; Random Allocation; Skin | 1989 |
Suppression of histamine-induced wheal response by loratadine (SCH 29851) over 28 days in man.
Topics: Adolescent; Adult; Chlorpheniramine; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Humans; Loratadine; Male; Piperidines; Skin; Tachyphylaxis; Time Factors | 1986 |
Effects of loratadine (SCH 29851) in suppression of histamine-induced skin wheals.
Topics: Adolescent; Adult; Clinical Trials as Topic; Cyproheptadine; Dose-Response Relationship, Drug; Histamine; Humans; Hypnotics and Sedatives; Loratadine; Male; Urticaria | 1988 |
[The effect of loratadine on skin and bronchial reactivity and histamine liberation from basophils in patients with atopic asthma and allergic rhinitis].
Topics: Asthma; Basophils; Bronchial Provocation Tests; Histamine; Histamine Release; Humans; Loratadine; Rhinitis, Allergic, Seasonal; Skin Tests; Spirometry | 1994 |
[Effect of loratadine, selective antagonist of histamine H1 receptors, on histamine-induced bronchoconstriction].
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Drug Administration Schedule; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Receptors, Histamine H1 | 1995 |
Duration of effect of loratadine and terfenadine administered once a day for one week on cutaneous and inhaled reactivity to histamine.
Topics: Administration, Inhalation; Adult; Aged; Asthma; Bronchoconstriction; Dose-Response Relationship, Drug; Drug Interactions; Female; Forced Expiratory Volume; Histamine; Humans; Loratadine; Male; Middle Aged; Single-Blind Method; Skin; Terfenadine; Time Factors; Vital Capacity | 1993 |
Onset of action in the nasal antihistaminic effect of cetirizine and loratadine in patients with allergic rhinitis.
Topics: Adult; Airway Resistance; Animals; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Infant, Newborn; Loratadine; Male; Nasal Mucosa; Nasal Provocation Tests; Rhinitis, Allergic, Seasonal; Time Factors | 1997 |
Loratadine treatment of rhinitis due to pollen allergy reduces epithelial ICAM-1 expression.
Topics: Adolescent; Adult; Blood Proteins; Cetirizine; Eosinophil Granule Proteins; Eosinophil Peroxidase; Eosinophils; Epithelial Cells; Female; Histamine; Histamine H1 Antagonists; Humans; Immunohistochemistry; Intercellular Adhesion Molecule-1; Leukocyte Count; Loratadine; Male; Nasal Lavage Fluid; Nasal Mucosa; Neutrophils; Peroxidase; Peroxidases; Rhinitis, Allergic, Seasonal; Ribonucleases; Seasons | 1997 |
Effects of H1 antagonists on the cutaneous vascular response to histamine and bradykinin: a study using scanning laser Doppler imaging.
Topics: Adult; Bradykinin; Cetirizine; Dermatitis, Allergic Contact; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Microcirculation; Microdialysis; Middle Aged; Skin | 1998 |
Changes in skin-test reactivity do not correlate with clinical efficacy of H1-blockers in seasonal allergic rhinitis.
Topics: Adolescent; Adult; Allergens; Astemizole; Child; Conjunctiva; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Nose; Rhinitis, Allergic, Seasonal; Skin Tests; Treatment Outcome | 1998 |
Nasal effect of cetirizine and loratadine at 24 hours in patients with allergic rhinitis.
Topics: Adult; Cetirizine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Nasal Mucosa; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal | 1998 |
Comparison between nasal provocation tests and skin tests in patients treated with loratadine and cetirizine.
Topics: Adult; Allergens; Anti-Allergic Agents; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Nasal Provocation Tests; Poaceae; Rhinitis, Allergic, Seasonal; Skin Tests | 1999 |
A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects.
Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Immediate; Imidazoles; Loratadine; Male; Piperidines; Skin Tests; Terfenadine; Urticaria | 1999 |
Comparison of the response to histamine challenge of the nose and the maxillary sinus: effect of loratadine.
Topics: Adult; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Male; Maxillary Sinus; Nose; Pilot Projects; Reflex; Serum Albumin; Sneezing | 1999 |
Effects of acrivastine, loratadine and cetirizine on histamine-induced wheal and flare responses.
Topics: Adult; Cetirizine; Cross-Over Studies; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Single-Blind Method; Triprolidine; Urticaria | 1999 |
Comparison of the effects of levocetirizine and loratadine on histamine-induced wheal, flare, and itch in human skin.
Topics: Anti-Allergic Agents; Cetirizine; Double-Blind Method; Histamine; Humans; Hypersensitivity, Immediate; Loratadine; Skin Tests; Urticaria | 2001 |
A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.
Topics: Adult; Benzimidazoles; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Piperidines; Terfenadine; Treatment Outcome; Urticaria | 2002 |
Rapid effects of olopatadine hydrochloride on the histamine-induced skin responses.
Topics: Administration, Oral; Adult; Cross-Over Studies; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Middle Aged; Probability; Pruritus; Reference Values; Skin Tests; Treatment Outcome; Urticaria | 2002 |
Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state.
Topics: Adolescent; Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Loratadine; Male; Piperidines; Skin Tests; Terfenadine | 2002 |
The effects of montelukast on intradermal wheal and flare.
Topics: Acetates; Adolescent; Adult; Aged; Anti-Allergic Agents; Candida albicans; Cyclopropanes; Double-Blind Method; Female; Follow-Up Studies; Histamine; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Prospective Studies; Quinolines; Rhinitis, Allergic, Seasonal; Skin Tests; Sulfides | 2003 |
Comparison of the effects of desloratadine and levocetirizine on histamine-induced wheal, flare and itch in human skin.
Topics: Adult; Anti-Allergic Agents; Cetirizine; Cross-Over Studies; Double-Blind Method; Erythema; Histamine; Histamine H1 Antagonists; Humans; Injections, Intradermal; Laser-Doppler Flowmetry; Loratadine; Male; Pruritus; Regional Blood Flow; Skin | 2003 |
Comparative activity of cetirizine and desloratadine on histamine-induced wheal-and-flare responses during 24 hours.
Topics: Adolescent; Adult; Anti-Allergic Agents; Area Under Curve; Cetirizine; Cross-Over Studies; Female; Histamine; Humans; Loratadine; Male; Middle Aged; Skin Tests; Time Factors; Urticaria | 2004 |
[Comparative activity of antihistamines on area under dose-response curve from histamine-induced wheal and flare responses in human skin].
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Area Under Curve; Benzimidazoles; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests; Time Factors; Urticaria | 2004 |
The effect of montelukast (10mg daily) and loratadine (10mg daily) on wheal, flare and itching reactions in skin prick tests.
Topics: Acetates; Allergens; Antipruritics; Capsules; Codeine; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Female; Histamine; Humans; Leukotriene Antagonists; Loratadine; Male; Pollen; Pruritus; Quinolines; Skin; Skin Tests; Sulfides; Time Factors; Treatment Outcome; Urticaria | 2007 |
A comparison of levocetirizine and desloratadine in the histamine-induced wheal and flare response in human skin in vivo.
Topics: Adult; Cetirizine; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity, Immediate; Loratadine; Male; Middle Aged; Piperazines; Skin; Skin Tests; Urticaria | 2006 |
[Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial].
Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Placebos; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria | 2006 |
[The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial].
Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Drug Administration Schedule; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Regional Blood Flow; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria | 2006 |
A comparison of ebastine 10 mg fast-dissolving tablet with oral desloratadine and placebo in inhibiting the cutaneous reaction to histamine in healthy adults.
Topics: Adult; Butyrophenones; Chemistry, Pharmaceutical; Dermatitis, Contact; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Pain Measurement; Patient Acceptance of Health Care; Piperidines; Skin; Tablets; Treatment Outcome | 2007 |
Comparison of inhibition of cutaneous histamine reaction of ebastine fast-dissolving tablet (20 mg) versus desloratadine capsule (5 mg): a randomized, double-blind, double-dummy, placebo-controlled, three-period crossover study in healthy, nonatopic adult
Topics: Adolescent; Adult; Butyrophenones; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Pain Measurement; Piperidines; Pruritus; Skin; Skin Tests | 2007 |
Nasal challenge with allergen leads to maxillary sinus inflammation.
Topics: Adult; Albumins; Ambrosia; Anti-Allergic Agents; Cross-Over Studies; Double-Blind Method; Eosinophils; Female; Histamine; Humans; Loratadine; Male; Maxillary Sinusitis; Nasal Lavage Fluid; Nasal Mucosa; Nasal Provocation Tests; Placebos; Plant Extracts; Rhinitis, Allergic, Seasonal | 2008 |
Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.
Topics: Adult; Allergens; Animals; Dermatophagoides pteronyssinus; Dibenzazepines; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine; Imidazoles; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome; Urticaria | 2009 |
Plasma histamine levels (H) during adjunctive H1-receptor antagonist treatment with loratadine in patients with active inflammatory bowel disease (IBD).
Topics: Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Colitis, Ulcerative; Crohn Disease; Histamine; Histamine H1 Antagonists; Humans; Inflammatory Bowel Diseases; Loratadine; Mesalamine; Prednisolone | 2010 |
Comparison of effects of 5 and 10 mg oral desloratadine and levocetirizine on histamine-induced wheal and flare response in healthy volunteers.
Topics: Administration, Oral; Adult; Anti-Allergic Agents; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Healthy Volunteers; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Middle Aged; Time Factors; Urticaria; Young Adult | 2013 |
Comparative efficacy of bilastine, desloratadine and rupatadine in the suppression of wheal and flare response induced by intradermal histamine in healthy volunteers.
Topics: Adult; Benzimidazoles; Cross-Over Studies; Cyproheptadine; Double-Blind Method; Female; Healthy Volunteers; Histamine; Histamine Antagonists; Humans; Injections, Intradermal; Loratadine; Male; Piperidines; Skin | 2017 |
Inhibitory effect of Phlai capsules on skin test responses among allergic rhinitis patients: a randomized, three-way crossover study.
Topics: Adult; Allergens; Animals; Anti-Allergic Agents; Cross-Over Studies; Double-Blind Method; Histamine; Histamine Antagonists; Humans; Loratadine; Mites; Phytotherapy; Plant Extracts; Rhinitis, Allergic; Skin; Skin Tests; Zingiberaceae | 2017 |
34 other study(ies) available for loratadine and histamine
Article | Year |
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Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4 | 2005 |
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship | 2008 |
Development of a phospholipidosis database and predictive quantitative structure-activity relationship (QSAR) models.
Topics: | 2008 |
Increasing the Endoplasmic Reticulum Pool of the F508del Allele of the Cystic Fibrosis Transmembrane Conductance Regulator Leads to Greater Folding Correction by Small Molecule Therapeutics.
Topics: Alleles; Benzoates; Cells, Cultured; Cystic Fibrosis; Cystic Fibrosis Transmembrane Conductance Regulator; Endoplasmic Reticulum; Furans; Gene Deletion; HEK293 Cells; HeLa Cells; High-Throughput Screening Assays; Humans; Hydroxamic Acids; Microscopy, Fluorescence; Protein Folding; Protein Structure, Tertiary; Pyrazoles; RNA, Messenger; Small Molecule Libraries; Ubiquitination; Vorinostat | 2016 |
[Effect of loratadine (LO), a selective H1 antagonist, on histamine-induced bronchoconstriction].
Topics: Adult; Asthma; Bronchial Provocation Tests; Bronchoconstriction; Female; Histamine; Humans; Loratadine; Male; Middle Aged | 1992 |
Effects of antihistamines on cutaneous reactions and influx of eosinophils after local injection of PAF, kallikrein, compound 48/80 and histamine in patients with chronic urticaria and healthy subjects.
Topics: Adult; Aged; Chlorpheniramine; Chronic Disease; Eosinophils; Female; Histamine; Histamine H1 Antagonists; Humans; Kallikreins; Loratadine; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Skin; Urticaria | 1992 |
Selective inhibition of peripheral histamine responses by loratadine and terfenadine.
Topics: Animals; Benzhydryl Compounds; Bronchi; Cyproheptadine; Guinea Pigs; Histamine; Histamine Antagonists; Histamine H1 Antagonists; Histamine Release; Injections, Intravenous; Injections, Intraventricular; Loratadine; Lung; Lung Compliance; Male; Methacholine Compounds; Terfenadine | 1990 |
Sch 37370: a potent, orally active, dual antagonist of platelet-activating factor and histamine.
Topics: Administration, Oral; Animals; Binding, Competitive; Brain; Bronchial Spasm; Female; Guinea Pigs; Histamine; Histamine Antagonists; Humans; Loratadine; Lung; Macaca fascicularis; Male; Mice; Piperidines; Platelet Activating Factor; Platelet Aggregation; Pyrilamine; Rats | 1990 |
Evaluation of the CNS properties of SCH 29851, a potential non-sedating antihistamine.
Topics: Animals; Anticonvulsants; Autonomic Nervous System; Behavior, Animal; Binding, Competitive; Cerebral Cortex; Dioxanes; Dogs; Female; Guinea Pigs; Histamine; Histamine Antagonists; Hypnotics and Sedatives; Lethal Dose 50; Loratadine; Male; Mice; Physostigmine; Piperidines; Pyrilamine; Rats; Saimiri; Time Factors | 1984 |
Inhibitory activity of loratadine and descarboethoxyloratadine on expression of ICAM-1 and HLA-DR by nasal epithelial cells.
Topics: Adult; Histamine; Histamine H1 Antagonists; HLA-DR Antigens; Humans; In Vitro Techniques; Intercellular Adhesion Molecule-1; Loratadine; Middle Aged; Nasal Mucosa; Nasal Polyps; Piperidines; Pyridines; Turbinates | 1995 |
A magnetic resonance imaging evaluation of histamine-mediated allergic response in the guinea pig nasopharynx.
Topics: Animals; Guinea Pigs; Histamine; Loratadine; Magnetic Resonance Imaging; Male; Methacholine Chloride; Mucous Membrane; Nasopharynx; Ovalbumin; Oxymetazoline; Respiratory Hypersensitivity | 1993 |
Effect of loratadine on immediate and delayed type hypersensitivity reactions.
Topics: Acetylcholine; Animals; Edema; Granuloma; Guinea Pigs; Histamine; Histamine Release; Hypersensitivity, Delayed; In Vitro Techniques; Leukotriene D4; Leukotrienes; Loratadine; Lung; Male; Mast Cells; Muscle Contraction; Muscle, Smooth; Rats; Rats, Wistar; Serotonin | 1995 |
Inhibitory activity of loratadine and descarboxyethoxyloratadine on histamine-induced activation of endothelial cells.
Topics: Cells, Cultured; Endothelium, Vascular; Glyceraldehyde-3-Phosphate Dehydrogenases; Histamine; Histamine H1 Antagonists; Humans; Interleukin-6; Interleukin-8; Loratadine; P-Selectin; Polymerase Chain Reaction; RNA, Messenger | 1997 |
The potential of active metabolites of antihistamines in the management of allergic disease.
Topics: Anti-Inflammatory Agents; Butyrophenones; Cells, Cultured; Cetirizine; Chymases; Eosinophils; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity; Intercellular Adhesion Molecule-1; Interleukin-3; Interleukin-8; Loratadine; Mast Cells; Piperidines; Potassium Channel Blockers; Potassium Channels; Prostaglandin D2; Pyridines; Recombinant Fusion Proteins; Recombinant Proteins; Serine Endopeptidases; Terfenadine; Time Factors; Tryptases | 2000 |
Comparative antiallergic effects of second-generation H1-antihistamines ebastine, cetirizine and loratadine in preclinical models.
Topics: Aerosols; Airway Resistance; Algorithms; Animals; Anti-Allergic Agents; Bronchial Spasm; Butyrophenones; Cetirizine; Guinea Pigs; Histamine; Histamine H1 Antagonists; Leukotriene C4; Loratadine; Male; Ovalbumin; Piperidines | 2003 |
Desloratadine inhibits constitutive and histamine-stimulated nuclear factor-kappaB activity consistent with inverse agonism at the histamine H1 Receptor.
Topics: Animals; Chlorocebus aethiops; COS Cells; Histamine; Histamine Agonists; Histamine H1 Antagonists; Humans; Inhibitory Concentration 50; Loratadine; NF-kappa B; Receptors, Histamine H1 | 2004 |
Effect of loratadine on mouse models of atopic dermatitis associated pruritus.
Topics: Animals; Dermatitis, Atopic; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Loratadine; Mice; Mice, Hairless; Mice, Inbred ICR | 2005 |
Acute bacterial rhinosinusitis causes hyperresponsiveness to histamine challenge in mice.
Topics: Acute Disease; Animals; Dose-Response Relationship, Drug; Histamine; Histamine H1 Antagonists, Non-Sedating; Loratadine; Mice; Mice, Inbred BALB C; Mice, Inbred C57BL; Nasal Mucosa; Ovalbumin; Rhinitis; Sinusitis; Stem Cells; Streptococcus pneumoniae | 2005 |
Extra- and intracellular oxidant production in phorbol myristate acetate stimulated human polymorphonuclear leukocytes: modulation by histamine and H(1)-antagonist loratadine.
Topics: Carcinogens; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Neutrophils; Reactive Oxygen Species; Signal Transduction; Tetradecanoylphorbol Acetate | 2006 |
Effect of a Chinese herbal formula, Shi-Bi-Lin, on an experimental model of allergic rhinitis.
Topics: Animals; Anti-Allergic Agents; Disease Models, Animal; Drugs, Chinese Herbal; Eosinophils; Guinea Pigs; Histamine; Histamine H1 Antagonists, Non-Sedating; Immunoglobulin E; Immunoglobulin G; Leukotrienes; Loratadine; Nasal Lavage Fluid; Nasal Mucosa; Nitric Oxide Synthase Type II; Nitric Oxide Synthase Type III; Ovalbumin; Rhinitis; Sneezing; Thromboxane B2 | 2006 |
Spontaneous scratching behaviour in DS-Nh mice as a possible model for pruritus in atopic dermatitis.
Topics: Animals; Antipruritics; Cells, Cultured; Dermatitis, Atopic; Disease Models, Animal; Histamine; Histamine H1 Antagonists, Non-Sedating; Immunoglobulin E; Keratinocytes; Loratadine; Male; Mast Cells; Mice; Mice, Inbred Strains; Nerve Growth Factor; Pruritus; Skin; Specific Pathogen-Free Organisms | 2006 |
On the pharmacology and toxicology of neutrophils.
Topics: Benzothiepins; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Neutrophils; Peroxidase; Superoxide Dismutase; Tetradecanoylphorbol Acetate | 2006 |
Further studies on the mechanism of antiphagocyte-antioxidative effect of H1-antihistamines.
Topics: Antioxidants; Benzothiepins; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Neutrophils; Phagocytes; Reactive Oxygen Species | 2007 |
Comparison of inhibition of cutaneous histamine reaction of ebastine fast-dissolving tablet [20 mg] versus desloratadine capsule [5 mg]: a randomized, double-blind, double-dummy, placebo-controlled, three-period crossover study in healthy, nonatopic adult
Topics: Butyrophenones; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Piperidines; Randomized Controlled Trials as Topic; Skin Tests | 2007 |
Multiple H1-antihistamine-induced urticaria.
Topics: Administration, Oral; Adult; Drug Eruptions; Female; Histamine; Histamine H1 Antagonists; Humans; Immunologic Tests; Leukotriene B4; Loratadine; Piperidines; Pyridines; Skin Tests; Terfenadine; Urticaria | 2009 |
Evidence for the contribution of tumour necrosis factor in oedema formation induced by histamine in the hind paw of the rat.
Topics: Animals; Anti-Inflammatory Agents; Antibodies, Monoclonal; Dose-Response Relationship, Drug; Edema; Foot; Histamine; Histamine H1 Antagonists; Infliximab; Loratadine; Male; Rats; Rats, Wistar; Reverse Transcriptase Polymerase Chain Reaction; Thalidomide; Tumor Necrosis Factor Inhibitors; Tumor Necrosis Factors | 2009 |
Concomitant activity of histamine and cysteinyl leukotrienes on porcine nasal mucosal vessels and nasal inflammation in the rat.
Topics: Acetates; Animals; Cyclopropanes; Cysteine; Dose-Response Relationship, Drug; Drug Synergism; Drug Therapy, Combination; Female; Histamine; Histamine H1 Antagonists, Non-Sedating; Hypersensitivity; In Vitro Techniques; Leukotriene Antagonists; Leukotriene D4; Leukotrienes; Loratadine; Male; Nasal Mucosa; Neutrophil Infiltration; Quinolines; Rats; Rats, Inbred BN; Rhinitis; Sulfides; Sus scrofa | 2010 |
Synthesis and antihistamine evaluations of novel loratadine analogues.
Topics: Animals; Anti-Allergic Agents; Asthma; Guinea Pigs; Histamine; Histamine Antagonists; Ileum; Loratadine; Stereoisomerism | 2011 |
Design, synthesis and antihistamine evaluations of several N-hydroxyalkyl desloratadine analogues.
Topics: Animals; Asthma; Chemistry Techniques, Synthetic; Drug Design; Female; Guinea Pigs; Histamine; Histamine Antagonists; Loratadine; Male; Mice; Muscle Contraction; Muscle, Smooth | 2012 |
Anti-allergic and anti-inflammatory properties of a potent histamine H1 receptor antagonist, desloratadine citrate disodium injection, and its anti-inflammatory mechanism on EA.hy926 endothelial cells.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Capillary Permeability; Cell Survival; Chlorpheniramine; Edema; Endothelial Cells; Guinea Pigs; Histamine; Histamine H1 Antagonists; Humans; Inflammation Mediators; Loratadine; Male; Mice; Nasal Mucosa; Passive Cutaneous Anaphylaxis; Rats; Rhinitis | 2015 |
Desloratadine citrate disodium injection, a potent histamine H(1) receptor antagonist, inhibits chemokine production in ovalbumin-induced allergic rhinitis guinea pig model and histamine-induced human nasal epithelial cells via inhibiting the ERK1/2 and N
Topics: Animals; Anti-Allergic Agents; Cells, Cultured; Chemokine CCL2; Chemokine CCL5; Chemokines; Disease Models, Animal; Epithelial Cells; Extracellular Signal-Regulated MAP Kinases; Guinea Pigs; Histamine; Histamine H1 Antagonists; Humans; Injections; Interleukin-8; Loratadine; Nasal Lavage Fluid; Nasal Mucosa; NF-kappa B; Ovalbumin; Rhinitis, Allergic; Signal Transduction | 2015 |
BRET-based β-arrestin2 recruitment to the histamine H1 receptor for investigating antihistamine binding kinetics.
Topics: beta-Arrestin 2; Binding, Competitive; Bioluminescence Resonance Energy Transfer Techniques; Cetirizine; Dose-Response Relationship, Drug; HEK293 Cells; Histamine; Histamine Agonists; Histamine H1 Antagonists, Non-Sedating; Humans; Kinetics; Ligands; Loratadine; Luciferases, Firefly; Models, Biological; NFATC Transcription Factors; Promoter Regions, Genetic; Protein Binding; Radioligand Assay; Receptors, Histamine H1; Recombinant Fusion Proteins | 2016 |
The Effects of Combined Therapeutic Protocol on Allergic Rhinitis Symptoms and Molecular Determinants.
Topics: Allergens; Animals; Caspase 1; Fluticasone; Histamine; Immunoglobulin E; Leukotriene C4; Loratadine; Mice; Rhinitis, Allergic | 2022 |
Re-evaluation of over-the-counter histamine H1-receptor antagonists based on their effects on murine models of allergen-induced nasal hyperresponsiveness.
Topics: Allergens; Animals; Disease Models, Animal; Histamine; Histamine H1 Antagonists; Loratadine; Mice | 2022 |