loratadine and fluconazole

loratadine has been researched along with fluconazole in 9 studies

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's4 (44.44)29.6817
2010's5 (55.56)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
Bharate, SS; Vishwakarma, RA1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dösch, A; Kraemer, DM; Schöttker, B1
Bindslev-Jensen, C; Kim, H1
Miners, JO; Nair, PC; Pattanawongsa, A; Rowland, A1

Reviews

1 review(s) available for loratadine and fluconazole

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

8 other study(ies) available for loratadine and fluconazole

ArticleYear
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
    Journal of medicinal chemistry, 2001, Jul-19, Volume: 44, Issue:15

    Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water

2001
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
Thermodynamic equilibrium solubility measurements in simulated fluids by 96-well plate method in early drug discovery.
    Bioorganic & medicinal chemistry letters, 2015, Apr-01, Volume: 25, Issue:7

    Topics: Drug Discovery; Pharmaceutical Preparations; Solubility; Thermodynamics

2015
Severe hepatotoxicity after application of desloratadine and fluconazole.
    Acta haematologica, 2003, Volume: 110, Issue:1

    Topics: Adult; Antifungal Agents; Chemical and Drug Induced Liver Injury; Contraindications; Drug Interactions; Drug Therapy, Combination; Female; Fever of Unknown Origin; Fluconazole; Histamine H1 Antagonists, Non-Sedating; Humans; Immunoblastic Lymphadenopathy; Loratadine; Lymphoma, T-Cell; Stem Cell Transplantation

2003
Reported case of severe hepatotoxicity likely due to fluconazole and not desloratadine.
    Acta haematologica, 2004, Volume: 112, Issue:3

    Topics: Antifungal Agents; Chemical and Drug Induced Liver Injury; Fluconazole; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine

2004
Human UDP-Glucuronosyltransferase (UGT) 2B10: Validation of Cotinine as a Selective Probe Substrate, Inhibition by UGT Enzyme-Selective Inhibitors and Antidepressant and Antipsychotic Drugs, and Structural Determinants of Enzyme Inhibition.
    Drug metabolism and disposition: the biological fate of chemicals, 2016, Volume: 44, Issue:3

    Topics: Amitriptyline; Antidepressive Agents, Tricyclic; Antipsychotic Agents; Cell Line; Cotinine; Drug Interactions; Enzyme Inhibitors; Fluconazole; Glucuronosyltransferase; HEK293 Cells; Humans; Kinetics; Loratadine; Microsomes, Liver

2016