loratadine and fexofenadine

loratadine has been researched along with fexofenadine in 76 studies

Research

Studies (76)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's6 (7.89)18.2507
2000's54 (71.05)29.6817
2010's16 (21.05)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Jolliet, P; Morin, C; Morin, D; Pagliara, A; Rihoux, JP; Testa, B; Tillement, JP; Urien, S1
Cavalli, A; De Ponti, F; Poluzzi, E; Recanatini, M1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM1
Benz, RD; Contrera, JF; Kruhlak, NL; Matthews, EJ; Weaver, JL1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Caron, G; Ermondi, G; Visentin, S1
Sen, S; Sinha, N1
Hitchcock, SA1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Estes, KS; González, MA1
Christian, S; Jensen, M; Kind, P; Ricard, N; Stewart, J1
Mattila, MJ; Paakkari, I1
Fairweather, DB; Hindmarch, I; Shamsi, Z; Stanley, N1
Danielson, L; DeVos, C; Grant, JA; Rihoux, JP1
Dunn, N; Mann, RD; Pearce, GL; Shakir, S1
Abdelaziz, MM; Devalia, JL; Khair, OA1
Juniper, EF; Van Cauwenberge, P1
Capano, D; Harris, AG; Prenner, BM1
Benedetto, SR; Duncan, BS; Sloan, AS1
Affrime, M; Banfield, C; Batra, V; Clement, R; Gupta, S; Kantesaria, B; Marino, M1
Cummins, G; Lee, J; Okamoto, L1
Benko, LB1
Górska, M; Grzelewska-Rzymowska, I; Pietrzkowicz, M1
Cummins, G; Leahy, M; Liao, E1
DeVos, C; Grant, JA; Moulaert, B; Riethuisen, JM1
Wilson, AM1
Affrime, M; Banfield, C; Gupta, S; Lim, J; Marino, M1
Fridliand, DG; Gushchin, IS; Poroshina, IuA; Shul'zhenko, AE1
Coutie, WJ; Lipworth, BJ; Orr, LC; Sims, EJ; Wilson, AM1
Haggart, K; Lipworth, BJ; Sims, EJ; Wilson, AM1
Gu, X; Silver, NA; Simons, FE; Simons, KJ1
Bates, CE; Currie, GP; Lee, DK; Lipworth, BJ1
Jackson, CM; Lee, DK; Lipworth, BJ1
Boyce, M; Carey, W; Luria, X; Warrington, S1
Christian, CD; Crisalida, T; Economides, A; Georges, GC; Hale, M; Kaliner, MA; Liao, Y; Meeves, SG; White, MV; Woodworth, TH1
Glass, DJ; Harper, AS1
Grzelewska-Rzymowska, I1
Appajosyula, S; Gelfand, EW; Meeves, S1
Baroody, FM; deTineo, M; Maleckar, B; Moinuddin, R; Naclerio, RM1
Glass, D; Harper, A1
Fujihara, S; Gardiner, M; Haggart, K; Lee, DK; Lipworth, BJ1
Fooanant, S; Roongapinun, S; Wajajamreon, S1
Benedetti, MS; Diquet, B; Molimard, M1
Fujieda, S; Hyo, S; Kawada, R; Kitazawa, S; Takenaka, H1
Conboy-Ellis, K1
Boyle, J; Hindmarch, I; Johnsen, S; Meadows, R; Ridout, F1
Baltes, E; Benedetti, MS; Chatelain, P; Gillard, M1
Green, GR1
Brunton, S; Spangler, DL1
Elad, S; Heisler, S; Shalit, M1
Cohen, AD; Gan-El, U; Lieberman, N; Reuvni, H; Vardy, DA1
Camelo-Nunes, IC1
Blaiss, MS; Lehman, JM1
Aragane, Y; Ashenager, MS; Grgela, T; Kawada, A1
Kruszewski, J; Kłos, K; Sułek, K1
Kruszewski, J; Kruszewski, R; Kłos, K; Sułek, K1
Devillier, P; Faisy, C; Roche, N1
Ikezawa, Z; Inomata, N; Tatewaki, S1
Bachert, C1
dos Santos, RV; Lima, HC; Magerl, M; Mlynek, A1
Bagad, AS; Bahekar, PC; Chidrewar, GU; Mandhane, SN; Mehetre, SV; Pawar, CA; Rajamannar, T; Rao, CT; Shah, JH1
Moeller, ML; Nahata, MC; Phan, H1
Crowe, A; Wright, C1
Church, MK; Maurer, M1
Anoopkumar-Dukie, S; Grant, GD; Kavanagh, JJ; Naicker, P1
Atia, NN; El-Gizawy, SM; El-Kommos, ME; Hosny, NM1
Plichta, D; Spiewak, R1
Chen, M; Chen, W; Chen, X; Guo, A; He, Y; Li, J; Liu, Z; Su, J; Wen, S; Yan, S; Zhang, C; Zhang, J; Zhao, Y; Zhou, H; Zhu, W1
Enk, CD; Levi, A1
Ji, Q; Liu, Y; Ye, XJ; Zhao, CL1
Apfelbacher, CJ; Böhmer, MM; Carter, B; Jupiter, A; Matterne, U; Weisshaar, E1
Enk, CD; Hodak, E; Lapidoth, M; Levi, A; Mazor, S; Snast, I; Uvaidov, V1

Reviews

18 review(s) available for loratadine and fexofenadine

ArticleYear
Structural modifications that alter the P-glycoprotein efflux properties of compounds.
    Journal of medicinal chemistry, 2012, Jun-14, Volume: 55, Issue:11

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Cell Line; Central Nervous System Agents; Central Nervous System Diseases; Drug Design; Humans; Models, Molecular; Permeability; Structure-Activity Relationship

2012
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
Pharmacokinetic overview of oral second-generation H1 antihistamines.
    International journal of clinical pharmacology and therapeutics, 1998, Volume: 36, Issue:5

    Topics: Astemizole; Blood-Brain Barrier; Cetirizine; Histamine H1 Antagonists; Humans; Loratadine; Structure-Activity Relationship; Terfenadine; Therapeutic Equivalency; Torsades de Pointes

1998
Variations among non-sedating antihistamines: are there real differences?
    European journal of clinical pharmacology, 1999, Volume: 55, Issue:2

    Topics: Astemizole; Benzimidazoles; Butyrophenones; Central Nervous System; Cetirizine; Drug Interactions; Heart; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Loratadine; Piperidines; Potassium Channel Blockers; Terfenadine; Triprolidine

1999
[The effect of second generation histamine antagonists on the heart].
    Pneumonologia i alergologia polska, 2001, Volume: 69, Issue:3-4

    Topics: Animals; Area Under Curve; Astemizole; Butyrophenones; Electrocardiography; Heart; Histamine H1 Antagonists; Humans; Loratadine; Piperidines; Tachycardia; Terfenadine; Torsades de Pointes

2001
Are antihistamines useful in managing asthma?
    Current opinion in allergy and clinical immunology, 2002, Volume: 2, Issue:1

    Topics: Acetates; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Bronchospirometry; Cetirizine; Cyclopropanes; Drug Therapy, Combination; Histamine H1 Antagonists; Humans; Loratadine; Mannitol; Quinolines; Rhinitis; Sulfides; Terfenadine

2002
[Clinical aspects of anti-inflammatory action of antihistamines].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2003, Volume: 14, Issue:84

    Topics: Cetirizine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Loratadine; Piperazines; Terfenadine

2003
Anti-inflammatory activity of H1-receptor antagonists: review of recent experimental research.
    Current medical research and opinion, 2004, Volume: 20, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Butyrophenones; Cells, Cultured; Histamine H1 Antagonists; Loratadine; Piperidines; Terfenadine

2004
Comparison of pharmacokinetics and metabolism of desloratadine, fexofenadine, levocetirizine and mizolastine in humans.
    Fundamental & clinical pharmacology, 2004, Volume: 18, Issue:4

    Topics: Absorption; Animals; Area Under Curve; Benzimidazoles; Biological Availability; Cetirizine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Metabolic Clearance Rate; Piperazines; Terfenadine; Tissue Distribution

2004
Management of seasonal allergic rhinitis: comparative efficacy of the newer-generation prescription antihistamines.
    Journal of the American Academy of Nurse Practitioners, 2005, Volume: 17, Issue:8

    Topics: Adolescent; Adult; Cetirizine; Child; Child, Preschool; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Nurse Practitioners; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome

2005
Efficacy and central nervous system impairment of newer-generation prescription antihistamines in seasonal allergic rhinitis.
    Southern medical journal, 2006, Volume: 99, Issue:6

    Topics: Central Nervous System; Cetirizine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Quality of Life; Rhinitis, Allergic, Seasonal; Terfenadine

2006
New antihistamines: a critical view.
    Jornal de pediatria, 2006, Volume: 82, Issue:5 Suppl

    Topics: Anti-Allergic Agents; Blood-Brain Barrier; Central Nervous System Diseases; Cetirizine; Child; Cyproheptadine; Heart Diseases; Histamine H1 Antagonists, Non-Sedating; Humans; Hypersensitivity; Loratadine; Mast Cells; Piperazines; Receptors, Histamine H1; Terfenadine

2006
Selecting the optimal oral antihistamine for patients with allergic rhinitis.
    Drugs, 2006, Volume: 66, Issue:18

    Topics: Administration, Oral; Cardiovascular System; Central Nervous System; Cetirizine; Drug Interactions; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Long QT Syndrome; Loratadine; Piperazines; Practice Guidelines as Topic; Quality of Life; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome

2006
Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review.
    Clinical pharmacokinetics, 2008, Volume: 47, Issue:4

    Topics: Cetirizine; Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Terfenadine; Urticaria

2008
A review of the efficacy of desloratadine, fexofenadine, and levocetirizine in the treatment of nasal congestion in patients with allergic rhinitis.
    Clinical therapeutics, 2009, Volume: 31, Issue:5

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Cetirizine; Child; Clinical Trials as Topic; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Middle Aged; Nasal Obstruction; Rhinitis, Allergic, Seasonal; Terfenadine; Treatment Outcome; Young Adult

2009
H(1)-antihistamines and urticaria: how can we predict the best drug for our patient?
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2012, Volume: 42, Issue:10

    Topics: Anti-Allergic Agents; Cetirizine; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Predictive Value of Tests; Skin Tests; Terfenadine; Urticaria

2012
[Pharmacotherapy of urticaria--an analysis of the discrepancies between guidelines of expert bodies, registration documents and evidence for the effectiveness of drugs].
    Przeglad lekarski, 2013, Volume: 70, Issue:12

    Topics: Administration, Oral; Administration, Topical; Anti-Allergic Agents; Benzimidazoles; Cetirizine; Glucocorticoids; Histamine Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Piperidines; Poland; Practice Guidelines as Topic; Terfenadine; Treatment Outcome; Urticaria

2013
Oral H1 antihistamines as 'add-on' therapy to topical treatment for eczema.
    The Cochrane database of systematic reviews, 2019, Jan-22, Volume: 1

    Topics: Administration, Oral; Administration, Topical; Adult; Cetirizine; Chemotherapy, Adjuvant; Child; Eczema; Histamine H1 Antagonists; Humans; Loratadine; Outcome Assessment, Health Care; Pruritus; Randomized Controlled Trials as Topic; Terfenadine

2019

Trials

25 trial(s) available for loratadine and fexofenadine

ArticleYear
Link between patient preferences and treatment outcomes in seasonal allergic rhinitis: an empiric investigation.
    Clinical therapeutics, 1999, Volume: 21, Issue:1

    Topics: Adult; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Patient Satisfaction; Rhinitis, Allergic, Perennial; Surveys and Questionnaires; Terfenadine; Treatment Outcome

1999
A double-blind, placebo-controlled investigation of the effects of fexofenadine, loratadine and promethazine on cognitive and psychomotor function.
    British journal of clinical pharmacology, 1999, Volume: 48, Issue:2

    Topics: Adult; Cognition; Cross-Over Studies; Double-Blind Method; Female; Flicker Fusion; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Loratadine; Male; Middle Aged; Promethazine; Psychomotor Performance; Reaction Time; Terfenadine; Wrist

1999
A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects.
    Allergy, 1999, Volume: 54, Issue:7

    Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Immediate; Imidazoles; Loratadine; Male; Piperidines; Skin Tests; Terfenadine; Urticaria

1999
Comparison of the efficacy, safety and quality of life provided by fexofenadine hydrochloride 120 mg, loratadine 10 mg and placebo administered once daily for the treatment of seasonal allergic rhinitis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2000, Volume: 30, Issue:6

    Topics: Adolescent; Adult; Child; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Quality of Life; Rhinitis, Allergic, Seasonal; Surveys and Questionnaires; Terfenadine; Treatment Outcome

2000
Efficacy and tolerability of loratadine versus fexofenadine in the treatment of seasonal allergic rhinitis: a double-blind comparison with crossover treatment of nonresponders.
    Clinical therapeutics, 2000, Volume: 22, Issue:6

    Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Child; Cross-Over Studies; Double-Blind Method; Female; Humans; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Seasonal; Terfenadine

2000
Pharmacokinetic and safety profile of desloratadine and fexofenadine when coadministered with azithromycin: a randomized, placebo-controlled, parallel-group study.
    Clinical therapeutics, 2001, Volume: 23, Issue:3

    Topics: Adolescent; Adult; Anti-Bacterial Agents; Azithromycin; Electrocardiography; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Terfenadine

2001
A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 88, Issue:2

    Topics: Adult; Benzimidazoles; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Piperidines; Terfenadine; Treatment Outcome; Urticaria

2002
Grapefruit juice reduces the oral bioavailability of fexofenadine but not desloratadine.
    Clinical pharmacokinetics, 2002, Volume: 41, Issue:4

    Topics: Administration, Oral; Adult; Area Under Curve; Beverages; Biological Availability; Citrus; Confidence Intervals; Cross-Over Studies; Electrocardiography; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Terfenadine

2002
A comparison of once daily fexofenadine versus the combination of montelukast plus loratadine on domiciliary nasal peak flow and symptoms in seasonal allergic rhinitis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2002, Volume: 32, Issue:1

    Topics: Acetates; Adult; Anti-Allergic Agents; Cross-Over Studies; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Humans; Leukotriene Antagonists; Loratadine; Nasal Cavity; Poaceae; Pollen; Pulmonary Ventilation; Quinolines; Rhinitis, Allergic, Seasonal; Single-Blind Method; Skin Tests; Sulfides; Terfenadine

2002
Effects of fexofenadine and desloratadine on subjective and objective measures of nasal congestion in seasonal allergic rhinitis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2002, Volume: 32, Issue:10

    Topics: Adult; Air Pollutants; Allergens; Cross-Over Studies; Double-Blind Method; Environmental Exposure; Female; Forced Expiratory Volume; Histamine H1 Antagonists; Humans; Loratadine; Lung; Male; Pollen; Rhinitis, Allergic, Seasonal; Terfenadine

2002
Clinical pharmacology of H1-antihistamines in the skin.
    The Journal of allergy and clinical immunology, 2002, Volume: 110, Issue:5

    Topics: Adult; Chlorpheniramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Kinetics; Loratadine; Male; Skin; Skin Tests; Terfenadine

2002
Comparative in vivo bioactivity of modern H1-antihistamines on AMP challenge in atopic asthma.
    The Journal of allergy and clinical immunology, 2003, Volume: 111, Issue:2

    Topics: Acetates; Adenosine Monophosphate; Adult; Aged; Asthma; Bronchial Provocation Tests; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Forced Expiratory Volume; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Piperazines; Respiratory Hypersensitivity; Terfenadine

2003
Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state.
    Drugs under experimental and clinical research, 2002, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Loratadine; Male; Piperidines; Skin Tests; Terfenadine

2002
Relative potency of fexofenadine HCl 180 mg, loratadine 10 mg, and placebo using a skin test model of wheal-and-flare suppression.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 90, Issue:6

    Topics: Adolescent; Adult; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Evaluation; Female; Histamine H1 Antagonists; Histamine Release; Humans; Loratadine; Male; Middle Aged; Reference Values; Skin Tests; Terfenadine; Time Factors; Treatment Outcome

2003
Comparison of the combinations of fexofenadine-pseudoephedrine and loratadine-montelukast in the treatment of seasonal allergic rhinitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2004, Volume: 92, Issue:1

    Topics: Acetates; Adolescent; Adult; Ambrosia; Anti-Allergic Agents; Cyclopropanes; Double-Blind Method; Drug Therapy, Combination; Ephedrine; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Quality of Life; Quinolines; Rhinitis, Allergic, Seasonal; Sulfides; Surveys and Questionnaires; Terfenadine; Treatment Outcome; Vasoconstrictor Agents

2004
Comparative effects of desloratadine, fexofenadine, and levocetirizine on nasal adenosine monophosphate challenge in patients with perennial allergic rhinitis.
    Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology, 2004, Volume: 34, Issue:4

    Topics: Adenosine Monophosphate; Adult; Aged; Aged, 80 and over; Anti-Allergic Agents; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Nasal Provocation Tests; Piperazines; Rhinitis, Allergic, Perennial; Terfenadine; Treatment Outcome

2004
Comparative efficacy of wheal-and-flare suppression among various non-sedating antihistamines and the pharmacologic insights to their efficacy.
    Journal of the Medical Association of Thailand = Chotmaihet thangphaet, 2004, Volume: 87, Issue:5

    Topics: Adolescent; Adult; Cetirizine; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Middle Aged; Terfenadine; Urticaria

2004
The efficacy of short-term administration of 3 antihistamines vs placebo under natural exposure to Japanese cedar pollen.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2005, Volume: 94, Issue:4

    Topics: Adult; Cetirizine; Cryptomeria; Double-Blind Method; Drug Administration Schedule; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Japan; Loratadine; Male; Middle Aged; Pollen; Quality of Life; Rhinitis, Allergic, Seasonal; Sneezing; Surveys and Questionnaires; Terfenadine

2005
Suppression of the histamine-induced wheal and flare response by fexofenadine HCl 60 mg twice daily, loratadine 10 mg once daily and placebo in healthy Japanese volunteers.
    Current medical research and opinion, 2005, Volume: 21, Issue:9

    Topics: Adult; Drug Therapy, Combination; Female; Histamine H1 Antagonists; Humans; Japan; Loratadine; Male; Middle Aged; Placebos; Prospective Studies; Terfenadine; United Kingdom; Urticaria

2005
[Inhibition of histamine-induced wheel after a recommended single dose administration of 10 mg cetirizine, 5 mg desloratadine, 120 i 180 mg fexofenadine, 5 mg levocetirizine and 10 mg loratadine--a randomized, double-blind, placebo controlled trial].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2006, Volume: 21, Issue:125

    Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Placebos; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria

2006
[The effect of 5-days of cetirizine, desloratadine, fexofenadine 120 and 180 mg, levocetirizine, loratadine treatment on the histamine-induced skin reaction and skin blood flow--a randomized, double-blind, placebo controlled trial].
    Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego, 2006, Volume: 21, Issue:125

    Topics: Administration, Oral; Adult; Cetirizine; Double-Blind Method; Drug Administration Schedule; Histamine; Histamine H1 Antagonists, Non-Sedating; Humans; Laser-Doppler Flowmetry; Loratadine; Male; Piperazines; Regional Blood Flow; Skin; Skin Tests; Terfenadine; Treatment Outcome; Urticaria

2006
Suppression of histamine- and allergen-induced skin reactions: comparison of first- and second-generation antihistamines.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2009, Volume: 102, Issue:6

    Topics: Adult; Allergens; Animals; Dermatophagoides pteronyssinus; Dibenzazepines; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Hydroxyzine; Imidazoles; Loratadine; Male; Middle Aged; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome; Urticaria

2009
The effects of antihistamines with varying anticholinergic properties on voluntary and involuntary movement.
    Clinical neurophysiology : official journal of the International Federation of Clinical Neurophysiology, 2013, Volume: 124, Issue:9

    Topics: Adult; Cholinergic Antagonists; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Promethazine; Reaction Time; Sleep Stages; Terfenadine; Tremor; Young Adult

2013
Association of FCER1A genetic polymorphisms with risk for chronic spontaneous urticaria and efficacy of nonsedating H1-antihistamines in Chinese patients.
    Archives of dermatological research, 2015, Volume: 307, Issue:2

    Topics: Adult; Asian People; Benzimidazoles; China; Female; Genotyping Techniques; Histamine H1 Antagonists, Non-Sedating; Humans; Immunoglobulin E; Loratadine; Male; Middle Aged; Pharmacogenetics; Polymorphism, Single Nucleotide; Receptors, IgE; Terfenadine; Urticaria; Young Adult

2015
[The effect of combined therapy on seasonal allergic rhinitis].
    Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery, 2016, Jul-05, Volume: 30, Issue:13

    Topics: Administration, Intranasal; Budesonide; Double-Blind Method; Glucocorticoids; Humans; Leukotriene Antagonists; Loratadine; Quality of Life; Rhinitis, Allergic; Rhinitis, Allergic, Seasonal; Terfenadine

2016

Other Studies

33 other study(ies) available for loratadine and fexofenadine

ArticleYear
Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist.
    Journal of medicinal chemistry, 1998, Mar-12, Volume: 41, Issue:6

    Topics: Alkanes; Animals; Biological Transport; Blood Proteins; Brain; Cetirizine; Histamine H1 Antagonists; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyzine; Isomerism; Models, Molecular; Molecular Conformation; Octanols; Rats; Water

1998
Toward a pharmacophore for drugs inducing the long QT syndrome: insights from a CoMFA study of HERG K(+) channel blockers.
    Journal of medicinal chemistry, 2002, Aug-29, Volume: 45, Issue:18

    Topics: Anti-Arrhythmia Agents; Cation Transport Proteins; Cluster Analysis; Databases, Factual; Ether-A-Go-Go Potassium Channels; Long QT Syndrome; Models, Molecular; Molecular Conformation; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship

2002
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4

2005
Assessment of the health effects of chemicals in humans: II. Construction of an adverse effects database for QSAR modeling.
    Current drug discovery technologies, 2004, Volume: 1, Issue:4

    Topics: Adverse Drug Reaction Reporting Systems; Artificial Intelligence; Computers; Databases, Factual; Drug Prescriptions; Drug-Related Side Effects and Adverse Reactions; Endpoint Determination; Models, Molecular; Quantitative Structure-Activity Relationship; Software; United States; United States Food and Drug Administration

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
GRIND-based 3D-QSAR and CoMFA to investigate topics dominated by hydrophobic interactions: the case of hERG K+ channel blockers.
    European journal of medicinal chemistry, 2009, Volume: 44, Issue:5

    Topics: Ether-A-Go-Go Potassium Channels; Humans; Hydrophobic and Hydrophilic Interactions; Models, Molecular; Potassium Channel Blockers; Quantitative Structure-Activity Relationship

2009
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
Sedation with "non-sedating" antihistamines: four prescription-event monitoring studies in general practice.
    BMJ (Clinical research ed.), 2000, Apr-29, Volume: 320, Issue:7243

    Topics: Adolescent; Adult; Adverse Drug Reaction Reporting Systems; Aged; Cetirizine; Child; Child, Preschool; Consciousness Disorders; Female; Histamine H1 Antagonists; Humans; Infant; Infant, Newborn; Loratadine; Male; Middle Aged; Product Surveillance, Postmarketing; Sleep Stages; Terfenadine; Triprolidine

2000
The potential of active metabolites of antihistamines in the management of allergic disease.
    Allergy, 2000, Volume: 55, Issue:5

    Topics: Anti-Inflammatory Agents; Butyrophenones; Cells, Cultured; Cetirizine; Chymases; Eosinophils; Granulocyte Colony-Stimulating Factor; Granulocyte-Macrophage Colony-Stimulating Factor; Hematopoietic Cell Growth Factors; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity; Intercellular Adhesion Molecule-1; Interleukin-3; Interleukin-8; Loratadine; Mast Cells; Piperidines; Potassium Channel Blockers; Potassium Channels; Prostaglandin D2; Pyridines; Recombinant Fusion Proteins; Recombinant Proteins; Serine Endopeptidases; Terfenadine; Time Factors; Tryptases

2000
Impact of interventions designed to increase market share and prescribing of fexofenadine at HMOs.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2000, Oct-01, Volume: 57, Issue:19

    Topics: Analysis of Variance; Astemizole; Cetirizine; Cost Savings; Drug Costs; Drug Utilization; Health Maintenance Organizations; Histamine H1 Antagonists; Humans; Loratadine; Marketing of Health Services; Practice Patterns, Physicians'; Retrospective Studies; Terfenadine; United States

2000
Newer antihistamines.
    The Medical letter on drugs and therapeutics, 2001, Apr-30, Volume: 43, Issue:1103

    Topics: Administration, Oral; Anti-Allergic Agents; Cetirizine; Chlorpheniramine; Conscious Sedation; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Psychomotor Performance; Rhinitis, Allergic, Seasonal; Somnambulism; Terfenadine

2001
[Seasonal allergic rhinitis. Nasal obstruction can also beh improved].
    MMW Fortschritte der Medizin, 2001, May-03, Volume: 143, Issue:18

    Topics: Anti-Allergic Agents; Double-Blind Method; Humans; Loratadine; Multicenter Studies as Topic; Nasal Obstruction; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal; Terfenadine

2001
A descriptive analysis of the use and cost of new-generation antihistamines in the treatment of allergic rhinitis: a retrospective database analysis.
    The American journal of managed care, 2001, Volume: 7, Issue:4 Suppl

    Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Databases as Topic; Drug Utilization Review; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Retrospective Studies; Rhinitis, Allergic, Perennial; Terfenadine; United States

2001
Ugly wait at the counter. Insurer pushes to make allergy drugs nonprescription.
    Modern healthcare, 2001, Aug-06, Volume: 31, Issue:32

    Topics: Anti-Allergic Agents; Health Services Accessibility; Humans; Insurance Carriers; Legislation, Drug; Loratadine; Nonprescription Drugs; Terfenadine; United States; United States Food and Drug Administration

2001
The costs of nonsedating antihistamine therapy for allergic rhinitis in managed care: an updated analysis.
    The American journal of managed care, 2001, Volume: 7, Issue:15 Suppl

    Topics: Adolescent; Adrenal Cortex Hormones; Adult; Aged; Cetirizine; Child; Cohort Studies; Drug Costs; Economics, Pharmaceutical; Female; Health Care Costs; Histamine H1 Antagonists; Humans; Loratadine; Male; Managed Care Programs; Middle Aged; Retrospective Studies; Rhinitis, Allergic, Perennial; Terfenadine; United States

2001
[Comparative antihistamine and anti-allergic effects of various antihistamine preparations].
    Terapevticheskii arkhiv, 2002, Volume: 74, Issue:3

    Topics: Adult; Anti-Allergic Agents; Butyrophenones; Cetirizine; Clemastine; Female; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Male; Piperidines; Pollen; Terfenadine

2002
Decongestant effects of antihistamines: a class effect?
    The Journal of allergy and clinical immunology, 2003, Volume: 111, Issue:3

    Topics: Controlled Clinical Trials as Topic; Histamine H1 Antagonists; Humans; Loratadine; Nasal Decongestants; Rhinitis, Allergic, Seasonal; Terfenadine

2003
Assessing satisfaction with desloratadine and fexofenadine in allergy patients who report dissatisfaction with loratadine.
    BMC family practice, 2003, Aug-13, Volume: 4

    Topics: Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Patient Satisfaction; Rhinitis, Allergic, Seasonal; Sleep Wake Disorders; Terfenadine; Treatment Outcome

2003
Assessing patient satisfaction with desloratadine after conversion from loratadine, fexofenadine, or cetirizine.
    Managed care interface, 2004, Volume: 17, Issue:2

    Topics: Anti-Allergic Agents; Cetirizine; Choice Behavior; Data Collection; Humans; Loratadine; Managed Care Programs; Nonprescription Drugs; Patient Satisfaction; Terfenadine; United States

2004
Histamine H1 receptor occupancy and pharmacodynamics of second generation H1-antihistamines.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2005, Volume: 54, Issue:9

    Topics: Animals; Cetirizine; CHO Cells; Cricetinae; Cricetulus; Histamine H1 Antagonists; Humans; Loratadine; Piperazines; Predictive Value of Tests; Receptors, Histamine H1; Recombination, Genetic; Terfenadine; Urticaria

2005
Treatment of ear pain in pilots in flight.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2005, Volume: 95, Issue:4

    Topics: Aerospace Medicine; Anti-Allergic Agents; Humans; Loratadine; Pain; Rhinitis, Allergic, Seasonal; Steroids; Terfenadine

2005
Saliva secretion in patients with allergic rhinitis.
    International archives of allergy and immunology, 2006, Volume: 141, Issue:3

    Topics: Adolescent; Adult; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Middle Aged; Patient Satisfaction; Pilot Projects; Rhinitis; Saliva; Salivary Glands; Terfenadine; Xerostomia

2006
Marketing of a new non-sedating antihistamine (fexofenadine) puts an additional burden on healthcare system resources in Israel.
    The European journal of general practice, 2006, Volume: 12, Issue:2

    Topics: Commerce; Cost-Benefit Analysis; Cross-Sectional Studies; Delivery of Health Care; Drug Prescriptions; Histamine H1 Antagonists, Non-Sedating; Humans; Israel; Loratadine; Marketing of Health Services; Terfenadine

2006
Inhibition of cytokine-induced expression of T-cell cytokines by antihistamines.
    Journal of investigational allergology & clinical immunology, 2007, Volume: 17, Issue:1

    Topics: Cells, Cultured; Cetirizine; Dibenzoxepins; Histamine H1 Antagonists, Non-Sedating; Humans; Immunosuppressive Agents; Interferon-gamma; Interleukin-12; Interleukin-4; Interleukin-5; Loratadine; Olopatadine Hydrochloride; RNA, Messenger; T-Lymphocytes; Terfenadine

2007
Multiple H1-antihistamine-induced urticaria.
    The Journal of dermatology, 2009, Volume: 36, Issue:4

    Topics: Administration, Oral; Adult; Drug Eruptions; Female; Histamine; Histamine H1 Antagonists; Humans; Immunologic Tests; Leukotriene B4; Loratadine; Piperidines; Pyridines; Skin Tests; Terfenadine; Urticaria

2009
Characterization of anti-inflammatory properties and evidence for no sedation liability for the novel antihistamine SUN-1334H.
    International archives of allergy and immunology, 2010, Volume: 151, Issue:1

    Topics: Acetates; Alcohols; Anaphylaxis; Animals; Anti-Inflammatory Agents, Non-Steroidal; Ataxia; Cetirizine; Drug Interactions; Female; Guinea Pigs; Histamine H1 Antagonists, Non-Sedating; Hydroxyzine; Hypersensitivity; Immunoglobulin G; Interleukin-4; Leukocytes; Loratadine; Male; Mice; Mice, Inbred BALB C; Nasal Lavage Fluid; Nasal Mucosa; Pentobarbital; Piperazines; Sneezing; Terfenadine

2010
Treatment of allergic rhinitis in infants and children: efficacy and safety of second-generation antihistamines and the leukotriene receptor antagonist montelukast.
    Drugs, 2009, Volume: 69, Issue:18

    Topics: Acetates; Administration, Oral; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Astemizole; Cetirizine; Child; Cyclopropanes; Drug Administration Schedule; Drug Interactions; Histamine H1 Antagonists, Non-Sedating; Humans; Ketotifen; Leukotriene Antagonists; Loratadine; Piperazines; Quinolines; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Safety; Sulfides; Tablets; Terfenadine; Treatment Outcome

2009
The impact of P-glycoprotein mediated efflux on absorption of 11 sedating and less-sedating antihistamines using Caco-2 monolayers.
    Xenobiotica; the fate of foreign compounds in biological systems, 2012, Volume: 42, Issue:6

    Topics: ATP Binding Cassette Transporter, Subfamily B, Member 1; Biological Transport; Caco-2 Cells; Cetirizine; Chromatography, High Pressure Liquid; Drug Interactions; Histamine H1 Antagonists; Humans; Hydrogen-Ion Concentration; Intestinal Absorption; Loratadine; Mass Spectrometry; Permeability; Terfenadine

2012
Thin layer chromatography-densitometric determination of some non-sedating antihistamines in combination with pseudoephedrine or acetaminophen in synthetic mixtures and in pharmaceutical formulations.
    Biomedical chromatography : BMC, 2014, Volume: 28, Issue:3

    Topics: Acetaminophen; Chromatography, Thin Layer; Densitometry; Histamine H1 Antagonists, Non-Sedating; Limit of Detection; Linear Models; Loratadine; Pseudoephedrine; Reproducibility of Results; Tablets; Terfenadine

2014
Treatment of solar urticaria using antihistamine and leukotriene receptor antagonist combinations tailored to disease severity.
    Photodermatology, photoimmunology & photomedicine, 2015, Volume: 31, Issue:6

    Topics: Acetates; Adolescent; Adult; Cetirizine; Child; Child, Preschool; Cyclopropanes; Drug Therapy, Combination; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Photosensitivity Disorders; Quinolines; Remission Induction; Remission, Spontaneous; Severity of Illness Index; Sulfides; Sunlight; Terfenadine; Ultraviolet Rays; Urticaria; Young Adult

2015
Real-life experience in the treatment of solar urticaria: retrospective cohort study.
    Clinical and experimental dermatology, 2019, Volume: 44, Issue:5

    Topics: Acetates; Adolescent; Adult; Aged; Anti-Allergic Agents; Cetirizine; Child; Cohort Studies; Cyclopropanes; Disease Management; Female; Histamine Antagonists; Humans; Leukotriene Antagonists; Loratadine; Male; Middle Aged; Omalizumab; Photosensitivity Disorders; Quinolines; Retrospective Studies; Sulfides; Terfenadine; Urticaria; Young Adult

2019