loratadine and ebastine

loratadine has been researched along with ebastine in 28 studies

Research

Studies (28)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's3 (10.71)18.2507
2000's23 (82.14)29.6817
2010's2 (7.14)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Carrupt, PA; Crivori, P; Cruciani, G; Testa, B1
Nagashima, R; Nishikawa, T; Tobita, M1
Bakker, RA; Leurs, R; Lim, HD; Ling, P; Thurmond, RL; van Rijn, RM1
Sen, S; Sinha, N1
Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ1
O'Hanlon, JF; Ramaekers, JG1
Mattila, MJ; Paakkari, I1
Danielson, L; DeVos, C; Grant, JA; Rihoux, JP1
Georges, GC; Lim, JC; Ratner, PH1
Górska, M; Grzelewska-Rzymowska, I; Pietrzkowicz, M1
DeVos, C; Grant, JA; Moulaert, B; Riethuisen, JM1
Fridliand, DG; Gushchin, IS; Poroshina, IuA; Shul'zhenko, AE1
Burri, P; Karppinen, A; Kautiainen, H; Petman, L; Reunala, T1
Paakkari, I1
Antonijoan, R; Barbanoj, M; Esbrí, R; Garcia, E; Gich, I; Gispert, J; Luria, X1
Gras, J; Llenas, J; Llupià, J1
Gispert, J; Hampel, F; Ratner, P1
Boyce, M; Carey, W; Luria, X; Warrington, S1
Appajosyula, S; Gelfand, EW; Meeves, S1
Hampel, F; Howland, W; Ratner, P; Van Bavel, J2
Chaikin, P; Gillen, MS; Malik, M; Pentikis, H; Rhodes, GR; Roberts, DJ1
Chuecos, F; Esbrí, R; Falqués, M; Gispert, J; Luria, X; Peris, F; Ratner, P; Rosales, MJ1
Antonijoan, RM; Barbanoj, MJ; Esbri, R; Fortea, J; García-Gea, C; Puntes, M; Valle, M1
Antonijoan, R; Barbanoj, MJ; Esbrí, R; Fortea, J; García-Gea, C; Pérez, J; Puntes, M; Serra, C1
Devillier, P1

Reviews

5 review(s) available for loratadine and ebastine

ArticleYear
Variations among non-sedating antihistamines: are there real differences?
    European journal of clinical pharmacology, 1999, Volume: 55, Issue:2

    Topics: Astemizole; Benzimidazoles; Butyrophenones; Central Nervous System; Cetirizine; Drug Interactions; Heart; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Loratadine; Piperidines; Potassium Channel Blockers; Terfenadine; Triprolidine

1999
[The effect of second generation histamine antagonists on the heart].
    Pneumonologia i alergologia polska, 2001, Volume: 69, Issue:3-4

    Topics: Animals; Area Under Curve; Astemizole; Butyrophenones; Electrocardiography; Heart; Histamine H1 Antagonists; Humans; Loratadine; Piperidines; Tachycardia; Terfenadine; Torsades de Pointes

2001
Cardiotoxicity of new antihistamines and cisapride.
    Toxicology letters, 2002, Feb-28, Volume: 127, Issue:1-3

    Topics: Arrhythmias, Cardiac; Astemizole; Benzimidazoles; Butyrophenones; Cetirizine; Cisapride; Heart Diseases; Histamine H1 Antagonists; Humans; Loratadine; Piperidines; Serotonin Receptor Agonists; Terfenadine; Triprolidine

2002
Anti-inflammatory activity of H1-receptor antagonists: review of recent experimental research.
    Current medical research and opinion, 2004, Volume: 20, Issue:1

    Topics: Animals; Anti-Inflammatory Agents; Butyrophenones; Cells, Cultured; Histamine H1 Antagonists; Loratadine; Piperidines; Terfenadine

2004
Meta-analysis of the efficacy of ebastine 20 mg compared to loratadine 10 mg and placebo in the symptomatic treatment of seasonal allergic rhinitis.
    International archives of allergy and immunology, 2005, Volume: 138, Issue:4

    Topics: Adult; Butyrophenones; Female; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Multicenter Studies as Topic; Piperidines; Placebos; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal

2005

Trials

13 trial(s) available for loratadine and ebastine

ArticleYear
Antihistamine effects on actual driving performance in a standard test: a summary of Dutch experience, 1989-94.
    Allergy, 1995, Volume: 50, Issue:3

    Topics: Automobile Driving; Benzimidazoles; Butyrophenones; Cetirizine; Clemastine; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Loratadine; Netherlands; Piperidines; Psychomotor Performance; Terfenadine; Triprolidine

1995
A double-blind, single-dose, crossover comparison of cetirizine, ebastine, epinastine, fexofenadine, terfenadine, and loratadine versus placebo: suppression of histamine-induced wheal and flare response for 24 h in healthy male subjects.
    Allergy, 1999, Volume: 54, Issue:7

    Topics: Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Dibenzazepines; Double-Blind Method; Histamine; Histamine H1 Antagonists; Histamine Release; Humans; Hypersensitivity, Immediate; Imidazoles; Loratadine; Male; Piperidines; Skin Tests; Terfenadine; Urticaria

1999
Comparison of once-daily ebastine 20 mg, ebastine 10 mg, loratadine 10 mg, and placebo in the treatment of seasonal allergic rhinitis. The Ebastine Study Group.
    The Journal of allergy and clinical immunology, 2000, Volume: 105, Issue:6 Pt 1

    Topics: Adolescent; Adult; Aged; Butyrophenones; Child; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Piperidines; Rhinitis, Allergic, Seasonal

2000
A double-blind, randomized, single-dose, crossover comparison of levocetirizine with ebastine, fexofenadine, loratadine, mizolastine, and placebo: suppression of histamine-induced wheal-and-flare response during 24 hours in healthy male subjects.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 88, Issue:2

    Topics: Adult; Benzimidazoles; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Piperidines; Terfenadine; Treatment Outcome; Urticaria

2002
Comparison of cetirizine, ebastine and loratadine in the treatment of immediate mosquito-bite allergy.
    Allergy, 2002, Volume: 57, Issue:6

    Topics: Adult; Animals; Butyrophenones; Cetirizine; Conscious Sedation; Cross-Over Studies; Culicidae; Double-Blind Method; Finland; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Insect Bites and Stings; Loratadine; Middle Aged; Piperidines; Pruritus; Severity of Illness Index; Time Factors; Treatment Outcome

2002
Efficacy of ebastine, cetirizine, and loratadine in histamine cutaneous challenges.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2002, Volume: 89, Issue:3

    Topics: Adolescent; Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Kinetics; Loratadine; Male; Middle Aged; Piperidines; Skin Tests

2002
Efficacy of ebastine in the control of nasal congestion associated with allergic rhinitis.
    Methods and findings in experimental and clinical pharmacology, 2003, Volume: 25, Issue:2

    Topics: Adult; Ambrosia; Butyrophenones; Dose-Response Relationship, Drug; Double-Blind Method; Female; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Male; Nasal Obstruction; Piperidines; Rhinitis, Allergic, Seasonal

2003
Inhibition of the histamine wheal by ebastine compared with cetirizine, fexofenadine and loratadine at steady state.
    Drugs under experimental and clinical research, 2002, Volume: 28, Issue:6

    Topics: Adolescent; Adult; Butyrophenones; Cetirizine; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Hypersensitivity, Immediate; Injections, Intradermal; Loratadine; Male; Piperidines; Skin Tests; Terfenadine

2002
Efficacy and safety of ebastine 20 mg compared to loratadine 10 mg once daily in the treatment of seasonal allergic rhinitis: a randomized, double-blind, placebo-controlled study.
    International archives of allergy and immunology, 2004, Volume: 133, Issue:4

    Topics: Adolescent; Adult; Aged; Butyrophenones; Child; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Least-Squares Analysis; Loratadine; Male; Middle Aged; Piperidines; Rhinitis, Allergic, Seasonal

2004
A randomized, double-blind, placebo-controlled study comparing the efficacy and safety of ebastine (20 mg and 10 mg) to loratadine 10 mg once daily in the treatment of seasonal allergic rhinitis.
    Journal of investigational allergology & clinical immunology, 2004, Volume: 14, Issue:1

    Topics: Administration, Oral; Butyrophenones; Cross-Over Studies; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up Studies; Humans; Loratadine; Male; Multivariate Analysis; Patch Tests; Piperidines; Probability; Rhinitis, Allergic, Seasonal; Severity of Illness Index; Treatment Outcome

2004
Co-administration of ketoconazole with H1-antagonists ebastine and loratadine in healthy subjects: pharmacokinetic and pharmacodynamic effects.
    British journal of clinical pharmacology, 2005, Volume: 59, Issue:3

    Topics: Adolescent; Adult; Antifungal Agents; Butyrophenones; Double-Blind Method; Drug Combinations; Electrocardiography; Heart Rate; Histamine H1 Antagonists; Humans; Ketoconazole; Loratadine; Male; Piperidines

2005
A comparison of ebastine 10 mg fast-dissolving tablet with oral desloratadine and placebo in inhibiting the cutaneous reaction to histamine in healthy adults.
    Clinical drug investigation, 2007, Volume: 27, Issue:7

    Topics: Adult; Butyrophenones; Chemistry, Pharmaceutical; Dermatitis, Contact; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Pain Measurement; Patient Acceptance of Health Care; Piperidines; Skin; Tablets; Treatment Outcome

2007
Comparison of inhibition of cutaneous histamine reaction of ebastine fast-dissolving tablet (20 mg) versus desloratadine capsule (5 mg): a randomized, double-blind, double-dummy, placebo-controlled, three-period crossover study in healthy, nonatopic adult
    Clinical therapeutics, 2007, Volume: 29, Issue:5

    Topics: Adolescent; Adult; Butyrophenones; Cross-Over Studies; Double-Blind Method; Female; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Male; Pain Measurement; Piperidines; Pruritus; Skin; Skin Tests

2007

Other Studies

10 other study(ies) available for loratadine and ebastine

ArticleYear
Predicting blood-brain barrier permeation from three-dimensional molecular structure.
    Journal of medicinal chemistry, 2000, Jun-01, Volume: 43, Issue:11

    Topics: Blood-Brain Barrier; Databases, Factual; Models, Chemical; Molecular Conformation; Multivariate Analysis; Permeability; Pharmaceutical Preparations; Pharmacokinetics; Structure-Activity Relationship

2000
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
    Bioorganic & medicinal chemistry letters, 2005, Jun-02, Volume: 15, Issue:11

    Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated

2005
Evaluation of histamine H1-, H2-, and H3-receptor ligands at the human histamine H4 receptor: identification of 4-methylhistamine as the first potent and selective H4 receptor agonist.
    The Journal of pharmacology and experimental therapeutics, 2005, Volume: 314, Issue:3

    Topics: Cell Line; Histamine Agonists; Humans; Imidazoles; Indoles; Isothiuronium; Ligands; Methylhistamines; Piperazines; Radioligand Assay; Receptors, G-Protein-Coupled; Receptors, Histamine; Receptors, Histamine H1; Receptors, Histamine H2; Receptors, Histamine H3; Receptors, Histamine H4

2005
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
    European journal of medicinal chemistry, 2011, Volume: 46, Issue:2

    Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests

2013
[Comparative antihistamine and anti-allergic effects of various antihistamine preparations].
    Terapevticheskii arkhiv, 2002, Volume: 74, Issue:3

    Topics: Adult; Anti-Allergic Agents; Butyrophenones; Cetirizine; Clemastine; Female; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Male; Piperidines; Pollen; Terfenadine

2002
Comparative antiallergic effects of second-generation H1-antihistamines ebastine, cetirizine and loratadine in preclinical models.
    Arzneimittel-Forschung, 2003, Volume: 53, Issue:2

    Topics: Aerosols; Airway Resistance; Algorithms; Animals; Anti-Allergic Agents; Bronchial Spasm; Butyrophenones; Cetirizine; Guinea Pigs; Histamine; Histamine H1 Antagonists; Leukotriene C4; Loratadine; Male; Ovalbumin; Piperidines

2003
[Antihistaminics. Side effects also after raising dosage at the placebo level].
    MMW Fortschritte der Medizin, 2003, May-29, Volume: 145, Issue:22

    Topics: Anti-Allergic Agents; Benzimidazoles; Butyrophenones; Cetirizine; Double-Blind Method; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Meta-Analysis as Topic; Piperidines; Placebos; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal

2003
[In seasonal and perennial rhinitis. Superiority to standard H1 blockers].
    MMW Fortschritte der Medizin, 2003, May-29, Volume: 145, Issue:22

    Topics: Anti-Allergic Agents; Butyrophenones; Cetirizine; Double-Blind Method; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Humans; Loratadine; Multicenter Studies as Topic; Piperidines; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Perennial; Rhinitis, Allergic, Seasonal; Time Factors

2003
Comparison of inhibition of cutaneous histamine reaction of ebastine fast-dissolving tablet [20 mg] versus desloratadine capsule [5 mg]: a randomized, double-blind, double-dummy, placebo-controlled, three-period crossover study in healthy, nonatopic adult
    Clinical therapeutics, 2007, Volume: 29, Issue:12

    Topics: Butyrophenones; Histamine; Histamine H1 Antagonists; Humans; Loratadine; Piperidines; Randomized Controlled Trials as Topic; Skin Tests

2007