loratadine has been researched along with chlorpheniramine in 35 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (8.57) | 18.7374 |
| 1990's | 11 (31.43) | 18.2507 |
| 2000's | 13 (37.14) | 29.6817 |
| 2010's | 8 (22.86) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Billah, MM; Ganguly, AK; Green, MJ; Kreutner, W; Piwinski, JJ; West, RE; Wong, JK | 1 |
| Carrupt, PA; Jolliet, P; Morin, C; Morin, D; Pagliara, A; Rihoux, JP; Testa, B; Tillement, JP; Urien, S | 1 |
| Albanese, MM; Anthes, JC; Billah, MM; Colizzo, F; Ganguly, AK; Green, MJ; Kaminski, JJ; Piwinski, JJ; West, RE; Wong, JK | 1 |
| Gao, F; Lombardo, F; Shalaeva, MY; Tupper, KA | 1 |
| Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA | 1 |
| Keserü, GM | 1 |
| Caron, G; Ermondi, G | 1 |
| Nagashima, R; Nishikawa, T; Tobita, M | 1 |
| Jia, L; Sun, H | 1 |
| Sen, S; Sinha, N | 1 |
| Afshari, CA; Chen, Y; Dunn, RT; Hamadeh, HK; Kalanzi, J; Kalyanaraman, N; Morgan, RE; van Staden, CJ | 1 |
| Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K | 1 |
| Juhlin, L; Pihl-Lundin, I | 1 |
| McMillan, JL; Simons, FE; Simons, KJ | 1 |
| Kaiser, HB | 1 |
| Longo, G; Marchesi, E; Poli, F; Ventura, A | 1 |
| Andreoli, A; Boner, AL; Marchesi, E; Miglioranzi, P; Richelli, C | 1 |
| Amkraut, HJ; Batenhorst, AS; Batenhorst, RL; Foster, TS; Graves, DA; Gural, RP; Kung, M | 1 |
| Gural, RP; Herron, J; Kassem, N; Roman, IJ | 1 |
| Bolser, DC; Chapman, RW; DeGennaro, FC; Hey, JA; O'Reilly, S | 1 |
| Elsayed, S; Holen, E; Nyfors, A | 1 |
| Crawford, WW; Klaustermeyer, WB; Lee, PH; Placik, IM | 1 |
| Fraser, TG; Maher, J; Pillay, N; Simons, FE; Simons, KJ | 1 |
| Nwawolo, CC; Olusesi, AD | 1 |
| Del Rio, E; Rebell, G; Reitberg, DP; Weiss, SL; Zaias, N | 1 |
| Gu, X; Silver, NA; Simons, FE; Simons, KJ | 1 |
| Aamir, K; Ashraf, R; Jalbani, GA; Shaikh, AM; Soomro, FM; Unar, MA | 1 |
| Ciz, M; Drabikova, K; Jancinova, V; Lojek, A; Macickova, T; Moravcova, J; Nosal, R; Pecivova, J | 1 |
| Ismaiel, OA; Jenkins, RG; Karnes, HT; Zhang, T | 1 |
| Fornés, L; Hernández-Pérez, M; Hossler, E; Lundberg, U; Paniz-Mondolfi, AE; Pérez-Alvarez, AM; Reyes-Jaimes, O | 1 |
| Chen, M; He, G; Jie, Q; Kodithuwakku, ND; Wu, Y; Xu, S; Yuan, X | 1 |
| Alexandria, AK; Maia, LC; Meckelburg, Nde A; Puetter, UT; Salles, JT; Souza, IP | 1 |
| Biagi, C; Calamelli, E; Cipriani, F; Donati, M; Melis, M; Monaco, L; Motola, D; Ricci, G; Vaccheri, A | 1 |
2 review(s) available for loratadine and chlorpheniramine
| Article | Year |
|---|---|
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk | 2016 |
H1-receptor antagonist treatment of seasonal allergic rhinitis.
Topics: Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Clemastine; Cyproheptadine; Histamine H1 Antagonists; Humans; Hydroxyzine; Ketotifen; Loratadine; Rhinitis, Allergic, Seasonal; Terfenadine | 1990 |
10 trial(s) available for loratadine and chlorpheniramine
| Article | Year |
|---|---|
A double-blind, single-dose, crossover comparison of cetirizine, terfenadine, loratadine, astemizole, and chlorpheniramine versus placebo: suppressive effects on histamine-induced wheals and flares during 24 hours in normal subjects.
Topics: Adult; Astemizole; Benzhydryl Compounds; Benzimidazoles; Cetirizine; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Histamine; Histamine H1 Antagonists; Humans; Hydroxyzine; Loratadine; Male; Placebos; Skin Tests; Terfenadine; Time Factors; Urticaria | 1990 |
[Loratadine and dexchlorpheniramine in the treatment of perennial allergic rhinitis in pediatric patients].
Topics: Age Factors; Child; Child, Preschool; Chlorpheniramine; Cyproheptadine; Female; Histamine Antagonists; Humans; Infant; Loratadine; Male; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Perennial; Stereoisomerism | 1990 |
Efficacy and safety of loratadine suspension in the treatment of children with allergic rhinitis.
Topics: Administration, Oral; Child; Child, Preschool; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Female; Histamine H1 Antagonists; Humans; Intradermal Tests; Loratadine; Male; Pollen; Randomized Controlled Trials as Topic; Rhinitis, Allergic, Seasonal | 1989 |
Pharmacologic evaluation of loratadine (SCH 29851), chlorpheniramine and placebo.
Topics: Adult; Chlorpheniramine; Cyproheptadine; Double-Blind Method; Histamine H1 Antagonists; Humans; Intradermal Tests; Loratadine; Male; Random Allocation | 1986 |
Suppression of histamine-induced wheal response by loratadine (SCH 29851) over 28 days in man.
Topics: Adolescent; Adult; Chlorpheniramine; Dose-Response Relationship, Drug; Histamine; Histamine Antagonists; Humans; Loratadine; Male; Piperidines; Skin; Tachyphylaxis; Time Factors | 1986 |
Comparative efficacy of terfenadine, loratadine, and astemizole in perennial allergic rhinitis.
Topics: Adrenergic Agents; Allergens; Ambulatory Care; Analysis of Variance; Anti-Allergic Agents; Astemizole; Bronchodilator Agents; Chlorpheniramine; Confidence Intervals; Cross-Over Studies; Ephedrine; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Nasal Mucosa; Nose; Rhinitis, Allergic, Perennial; Skin Tests; Terfenadine; Treatment Outcome | 1998 |
Central nervous system effects of H1-receptor antagonists in the elderly.
Topics: Aged; Blood Glucose; Brain; Cetirizine; Chlorpheniramine; Cognition Disorders; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Event-Related Potentials, P300; Female; Histamine H1 Antagonists; Histamine H2 Antagonists; Humans; Loratadine; Male; Memory Disorders; Psychomotor Performance; Safety; Skin Tests; Sleep Stages | 1999 |
Controlled clinical study of the efficacy of loratadine in Nigerian patients with allergic rhinitis.
Topics: Adult; Anti-Allergic Agents; Chlorpheniramine; Female; Histamine H1 Antagonists; Humans; Loratadine; Male; Middle Aged; Nigeria; Rhinitis, Allergic, Perennial; Treatment Outcome | 2001 |
Single-patient drug trial methodology for allergic rhinitis.
Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Child; Chlorpheniramine; Clinical Trials as Topic; Data Collection; Disorders of Excessive Somnolence; Female; Humans; Loratadine; Male; Middle Aged; Patient Selection; Randomized Controlled Trials as Topic; Reproducibility of Results; Research Design; Rhinitis, Allergic, Seasonal; Skin Tests; Surveys and Questionnaires | 2002 |
Clinical pharmacology of H1-antihistamines in the skin.
Topics: Adult; Chlorpheniramine; Double-Blind Method; Histamine H1 Antagonists; Humans; Kinetics; Loratadine; Male; Skin; Skin Tests; Terfenadine | 2002 |
23 other study(ies) available for loratadine and chlorpheniramine
| Article | Year |
|---|---|
Dual antagonists of platelet activating factor and histamine. Identification of structural requirements for dual activity of N-Acyl-4-(5,6-dihydro-11H-benzo [5,6]cyclohepta-[1,2-b]pyridin-11-ylidene)piperidines.
Topics: Animals; Guinea Pigs; Histamine H1 Antagonists; Indicators and Reagents; Lung; Molecular Structure; Piperidines; Platelet Activating Factor; Receptors, Histamine H1; Structure-Activity Relationship | 1991 |
Molecular properties and pharmacokinetic behavior of cetirizine, a zwitterionic H1-receptor antagonist.
Topics: Alkanes; Animals; Biological Transport; Blood Proteins; Brain; Cetirizine; Histamine H1 Antagonists; Humans; Hydrogen Bonding; Hydrogen-Ion Concentration; Hydroxyzine; Isomerism; Models, Molecular; Molecular Conformation; Octanols; Rats; Water | 1998 |
Dual antagonists of platelet activating factor and histamine. 3. Synthesis, biological activity and conformational implications of substituted N-acyl-bis-arylcycloheptapiperazines.
Topics: Histamine Antagonists; Molecular Conformation; Piperazines; Platelet Activating Factor; Stereoisomerism | 1998 |
ElogD(oct): a tool for lipophilicity determination in drug discovery. 2. Basic and neutral compounds.
Topics: 1-Octanol; Chromatography, High Pressure Liquid; Pharmaceutical Preparations; Solubility; Water | 2001 |
Rational use of in vitro P-glycoprotein assays in drug discovery.
Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera | 2001 |
Prediction of hERG potassium channel affinity by traditional and hologram qSAR methods.
Topics: Cation Transport Proteins; Databases, Factual; Discriminant Analysis; Ether-A-Go-Go Potassium Channels; Holography; Linear Models; Potassium Channel Blockers; Potassium Channels; Potassium Channels, Voltage-Gated; Quantitative Structure-Activity Relationship | 2003 |
Calculating virtual log P in the alkane/water system (log P(N)(alk)) and its derived parameters deltalog P(N)(oct-alk) and log D(pH)(alk).
Topics: 1-Octanol; Alkanes; Hydrogen-Ion Concentration; Least-Squares Analysis; Mathematics; Models, Chemical; Models, Molecular; Solvents; Water | 2005 |
A discriminant model constructed by the support vector machine method for HERG potassium channel inhibitors.
Topics: Animals; CHO Cells; Cricetinae; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Potassium Channel Blockers; Potassium Channels, Voltage-Gated | 2005 |
Support vector machines classification of hERG liabilities based on atom types.
Topics: Animals; Arrhythmias, Cardiac; CHO Cells; Computer Simulation; Cricetinae; Cricetulus; Discriminant Analysis; ERG1 Potassium Channel; Ether-A-Go-Go Potassium Channels; Humans; Models, Chemical; Patch-Clamp Techniques; Potassium Channel Blockers; Potassium Channels, Voltage-Gated; Predictive Value of Tests; ROC Curve | 2008 |
Predicting hERG activities of compounds from their 3D structures: development and evaluation of a global descriptors based QSAR model.
Topics: Computer Simulation; Ether-A-Go-Go Potassium Channels; Humans; Molecular Structure; Organic Chemicals; Quantitative Structure-Activity Relationship | 2011 |
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 11; ATP-Binding Cassette Transporters; Biological Transport; Chemical and Drug Induced Liver Injury; Cluster Analysis; Drug-Related Side Effects and Adverse Reactions; Humans; Liver; Male; Multidrug Resistance-Associated Proteins; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Recombinant Proteins; Risk Assessment; Risk Factors; Toxicity Tests | 2013 |
Effects of antihistamines on cutaneous reactions and influx of eosinophils after local injection of PAF, kallikrein, compound 48/80 and histamine in patients with chronic urticaria and healthy subjects.
Topics: Adult; Aged; Chlorpheniramine; Chronic Disease; Eosinophils; Female; Histamine; Histamine H1 Antagonists; Humans; Kallikreins; Loratadine; Male; Middle Aged; p-Methoxy-N-methylphenethylamine; Platelet Activating Factor; Skin; Urticaria | 1992 |
Pharmacological studies of allergic cough in the guinea pig.
Topics: Administration, Oral; Aerosols; Albuterol; Analysis of Variance; Animals; Antitussive Agents; Capsaicin; Chlorpheniramine; Cimetidine; Codeine; Cough; Drug Hypersensitivity; Guinea Pigs; Hexamethonium; Histamine Antagonists; Indomethacin; Injections, Subcutaneous; Ipratropium; Loratadine; Male; Ovalbumin; Piperidines; Receptors, Histamine H1; Receptors, Histamine H2 | 1995 |
The effect of H1 receptor antagonists on peripheral blood mononuclear cells, adenoid cells and primary cell lines.
Topics: Adenoids; Adult; Cell Division; Cell Line; Chlorpheniramine; Dermatitis, Atopic; Dose-Response Relationship, Drug; Female; Histamine H1 Antagonists; Humans; Leukocytes, Mononuclear; Loratadine; Male; Middle Aged; Terfenadine | 1995 |
Newer antihistamines.
Topics: Administration, Oral; Anti-Allergic Agents; Cetirizine; Chlorpheniramine; Conscious Sedation; Diphenhydramine; Dose-Response Relationship, Drug; Histamine H1 Antagonists; Humans; Hypersensitivity; Loratadine; Psychomotor Performance; Rhinitis, Allergic, Seasonal; Somnambulism; Terfenadine | 2001 |
To evaluate and compare the effects of first generation anti-histamine (chlorpheniramine maleate) and second generation anti-histamine (loratadine) on isolated trachea of rabbit.
Topics: Animals; Chlorpheniramine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Loratadine; Muscle Contraction; Muscle, Smooth; Rabbits; Trachea | 2004 |
Best drugs for what ails you: the brands to buy--and those to skip.
Topics: Acetaminophen; Anesthetics, Local; Cetirizine; Chlorpheniramine; Common Cold; Cough; Dextromethorphan; Diphenhydramine; Drug Costs; Drug Therapy; Emergencies; Expectorants; First Aid; Glycerol; Guaifenesin; Histamine Antagonists; Honey; Humans; Hypersensitivity; Ibuprofen; Influenza Vaccines; Influenza, Human; Loratadine; Nonprescription Drugs; Oxymetazoline; Pharyngitis; Propiophenones; Pseudoephedrine; Rhinitis; Sodium Chloride | 2009 |
H1-antihistamines and oxidative burst of professional phagocytes.
Topics: Benzothiepins; Brompheniramine; Chlorpheniramine; Dose-Response Relationship, Drug; Extracellular Space; Histamine H1 Antagonists; Humans; Intracellular Space; Loratadine; Luminescence; Luminol; Neutrophils; Oxidation-Reduction; Pheniramine; Respiratory Burst | 2009 |
Investigation of endogenous blood plasma phospholipids, cholesterol and glycerides that contribute to matrix effects in bioanalysis by liquid chromatography/mass spectrometry.
Topics: Chemical Fractionation; Chlorpheniramine; Cholesterol; Chromatography, Liquid; Erythrocytes; Glycerides; Humans; Loratadine; Models, Chemical; Phospholipids; Sensitivity and Specificity; Tandem Mass Spectrometry | 2010 |
Cutaneous lepidopterism: dermatitis from contact with moths of Hylesia metabus (Cramer 1775) (Lepidoptera: Saturniidae), the causative agent of caripito itch.
Topics: Adolescent; Adult; Anesthetics, Local; Animals; Antipruritics; Chlorpheniramine; Dermatitis, Contact; Dexamethasone; Drug Therapy, Combination; Female; Humans; Hydrocortisone; Lidocaine; Loratadine; Male; Middle Aged; Moths; Pruritus; Treatment Outcome; Triamcinolone Acetonide; Venezuela | 2011 |
Anti-allergic and anti-inflammatory properties of a potent histamine H1 receptor antagonist, desloratadine citrate disodium injection, and its anti-inflammatory mechanism on EA.hy926 endothelial cells.
Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Capillary Permeability; Cell Survival; Chlorpheniramine; Edema; Endothelial Cells; Guinea Pigs; Histamine; Histamine H1 Antagonists; Humans; Inflammation Mediators; Loratadine; Male; Mice; Nasal Mucosa; Passive Cutaneous Anaphylaxis; Rats; Rhinitis | 2015 |
Do pediatric medicines induce topographic changes in dental enamel?
Topics: Amoxicillin-Potassium Clavulanate Combination; Analgesics; Animals; Anti-Bacterial Agents; Cattle; Chlorpheniramine; Cold Temperature; Dental Enamel; Dipyrone; Hardness Tests; Hydrogen-Ion Concentration; Loratadine; Microscopy, Electron, Scanning; Spectrometry, X-Ray Emission; Statistics, Nonparametric; Surface Properties | 2016 |
Safety profile of H1-antihistamines in pediatrics: an analysis based on data from VigiBase.
Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Cetirizine; Child; Child Mortality; Child, Preschool; Chlorpheniramine; Databases, Factual; Diphenhydramine; Epilepsy; Female; Histamine H1 Antagonists; Humans; Infant; Infant, Newborn; Loratadine; Male; Pharmacovigilance; Stevens-Johnson Syndrome; World Health Organization | 2017 |