loperamide has been researched along with piperidines in 224 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 192 (85.71) | 18.7374 |
| 1990's | 23 (10.27) | 18.2507 |
| 2000's | 5 (2.23) | 29.6817 |
| 2010's | 3 (1.34) | 24.3611 |
| 2020's | 1 (0.45) | 2.80 |
| Authors | Studies |
|---|---|
| Clay, GA; Dajani, EZ; Mackerer, CR | 1 |
| Kawashima, K; Nakamura, H; Shimizu, M; Sohji, Y | 1 |
| Candy, DC; Harries, JT; Sandhu, B; Tripp, JH | 2 |
| Cutting, WA; Marshall, WC | 1 |
| Heap, J | 1 |
| Galambos, JT | 1 |
| Miyasato, K; Sato, J; Yanagita, T | 1 |
| Clay, GA; Lin, TK; Mackerer, CR | 1 |
| Fiasse, R; Mainguet, P | 1 |
| Dagevos, J; Huibregtse, K; Tytgat, GN; van den Ende, A | 1 |
| Jaffé, G | 1 |
| John, GI | 1 |
| Amery, W; Lange, AP; Secher, NJ | 1 |
| Avery, GS; Brogden, RN; Heel, RC; Speight, TM | 1 |
| Fiasse, R; Mainguet, P; Turine, JB | 1 |
| Barbezat, GO; Clain, JE; Halter, F | 1 |
| Markiewicz, A; Zahorska-Markiewicz, B | 1 |
| Fuller, BL; Killinger, JM; Weintraub, HS | 1 |
| Kawai, K; Misaki, F; Sasaki, Z | 1 |
| Bartnik, W; Butruk, E | 1 |
| Helsen, L; Heykants, JJ; Michiels, M; Van Nueten, JM | 1 |
| Fujiwara, M; Muramatsu, I; Nakashima, M; Shikimi, T | 1 |
| Arakawa, S; Hashimoto, M; Miyazaki, H; Nambu, K; Yoshida, K | 1 |
| Wundt, W | 1 |
| Piercey, MF; Ruwart, MJ | 1 |
| Hashimoto, M; Matsunaga, Y; Miyazaki, H; Nambu, K | 1 |
| Mizutani, M; Nakayama, S; Yamasato, T | 2 |
| Bianchi, C; Goi, A | 1 |
| Chapaux, J; Chapaux, P; Royer, E | 1 |
| Alioto, RL; Eash, JR; Krebs, JB; Mir, GN; Sperow, JW; Yelnosky, J | 1 |
| Paterson, ID | 1 |
| Behdjati, F; Geginat, G; Green, E; Kaeferstein, D | 1 |
| Nixon, HH | 1 |
| Kawashima, K; Shimizu, M; Sohji, Y | 2 |
| Martins, JK; Roedl, G | 1 |
| Giles, HG; Sellers, EM; Ti, TY | 1 |
| Sohji, Y; Suzuki, H; Yagasaki, O | 1 |
| Awouters, F; Mcguire, JL; Niemegeers, CJ | 1 |
| Brown, JW | 1 |
| Galambos, JT; Hersh, T; Schroder, S; Wenger, J | 1 |
| Pelemans, W; Vantrappen, F | 1 |
| Huibregtse, K; Meuwissen, SG; Tytgat, GN | 1 |
| Adaikan, PG; Karim, SM | 1 |
| Chevrel, B | 2 |
| Arteaga, I | 1 |
| Hendriks, R; Heykants, J; Michiels, M | 1 |
| Rogé, J | 1 |
| Huibregtse, K; Meuwissen, SG; Tijtgat, GN | 1 |
| Tytgat, GN | 1 |
| Buts, JP; de Meyer, R; Petit, BF | 1 |
| Awouters, F; Janssen, PA; Kuyps, J; Niemegeers, CJ | 1 |
| Moncrieff, J; Sommers, DK; van Wyk, M | 1 |
| Bhutta, TI; Tahir, KI | 1 |
| Otterson, MF; Sarna, SK | 1 |
| Henry, JA; Minton, NA | 1 |
| Gussin, RZ | 1 |
| Dashwood, MR; Sykes, RM; Thomson, CS | 1 |
| Petersen, KU; Wehner, F; Winterhager, JM | 2 |
| Clarke, PD; Miller, AR; Ramage, JK | 1 |
| Ericsson, CD; Johnson, PC | 1 |
| Cruz Luna, A; DuPont, HL; DuPont, MW; Ericsson, CD; Flores Sanchez, J; Mathewson, JJ; Mendiola Gomez, J | 1 |
| Cruz Luna, A; DuPont, HL; DuPont, MW; Ericsson, CD; Mathewson, JJ | 1 |
| Ciok, J; Dzieniszewski, J; Jarosz, M | 1 |
| Hopman, WP; Jansen, JB; Lamers, CB; Rosenbusch, G | 1 |
| Awouters, FH; Canters, LL; Megens, AA; Niemegeers, CJ | 1 |
| Bowie, MD; Hill, ID; Mann, MD; Motala, C | 1 |
| Loffeld, RJ; Soeters, PB | 1 |
| Eitrem, R | 1 |
| Bitsura, JA; DuPont, HL; Ericsson, CD; Johnson, PC; Mathewson, JJ; West, MS | 1 |
| Brown, DR; Chang, EB; Field, M; Wang, NS | 1 |
| Abdulla, MA; Al Bwardy, M; Hendrickse, RG; Karrar, ZA; Macfarlane, SB; Moody, JB | 1 |
| Ambrosi, B; Bochicchio, D; Colombo, P; Faglia, G; Ferrario, R | 2 |
| Cutting, WA | 1 |
| Gleispach, H; Leis, HJ | 1 |
| Cao, A; Hantz, E; Phadke, RS; Taillandier, E | 1 |
| Farack, UM; Loeschke, K; Schmid, T | 1 |
| Szüle, E | 1 |
| Bennish, ML; Butler, C; Speelman, P; van Loon, FP | 1 |
| Mack, RB | 1 |
| Emblem, R; Mørkrid, L; Stien, R | 1 |
| Bryson, JC; Dukes, GE; Heizer, WD; Kirby, MG; Powell, JR | 1 |
| Linseman, MA | 1 |
| Mellstrand, T | 1 |
| Balkovetz, DF; Ganapathy, V; Leibach, FH; Mahesh, VB; Miyamoto, Y; Tiruppathi, C | 1 |
| Domschke, W; Ruppin, H; Stoll, R | 1 |
| Burleigh, DE | 1 |
| Diener, M; Knobloch, SF; Rummel, W | 1 |
| Ambrosi, B; Bochicchio, D; Faglia, G | 2 |
| Gautret, B; Schmitt, H | 1 |
| Madsen, P; Matzen, P; Qvitzau, S | 1 |
| Minton, NA; Smith, PG | 1 |
| Bingen, E; Cezard, JP; Lambert-Zechovsky, N; Marinier, E; Mashako, L; Navarro, J | 1 |
| Ahsan, MA; Ilundain, A; Naftalin, RJ; Sandhu, BK; Smith, PM | 1 |
| Kurbatova, TS; Lobzhanidze, DN; Saakian, AG | 1 |
| Au-Yeung, CY; Leung, CP | 1 |
| Goncharenko, GV; Voznyĭ, EK | 1 |
| Bettinetti, GP; Giordano, F; Pavan, M; Pavesi, L | 1 |
| Lavö, B; Nielsen, AL; Stenstam, M | 1 |
| Hovdenak, N | 1 |
| Cordier, MP; Mozziconacci, G; Polonovski, C | 1 |
| Burnham, WR; McIntyre, A; O'Brien, JD; Thompson, DG; Walker, E | 1 |
| Perényi, G | 1 |
| Udvardi, G | 1 |
| Szigeti, A | 1 |
| Baldassarre, G; Calo' Gabrieli, G; Palasciano, G; Portincasa, P; Velardi, A | 1 |
| Jivegård, L; Svanvik, J | 2 |
| Alestig, K; Bergström, T; Thorén, K; Trollfors, B | 1 |
| Iatskiv, MV; Kriklivets, IuI; Maliukh, LS | 1 |
| Albano, O; Altomare, E; Banterle, C; Chiodo, F; Corazza, GR; Feliciani, M; Fontana, G; Gasbarrini, G; Stufano, N; Valpiani, D | 1 |
| Chow, CB; Leung, NK; Li, SH | 1 |
| Buéno, L; Fioramonti, J | 1 |
| Bueno, L; Fargeas, MJ; Fioramonti, J | 1 |
| Bingen, E; Cézard, JP; Lambert-Zechovsky, N; Marchand, M; Marinier, E; Navarro, J | 1 |
| Culver, PJ; Rattan, S | 1 |
| Basilisco, G; Bianchi, PA; Bozzani, A; Camboni, G; Paravicini, M | 1 |
| Faucon, B; Francomme, P; Parise, M | 1 |
| Kortenhaus, E; Wallenfels, M; Wienbeck, M | 1 |
| Angulo, AF; Banerjee, AK; Dhasmana, KM; Kong-A-San, J | 1 |
| Maas, CL; van Duin, CT; van Miert, AS | 1 |
| Arnbjörnsson, E; Breland, U; Kullendorff, CM; Okmian, L | 1 |
| Cookson, J; Hardcastle, J; Hardcastle, PT | 1 |
| Argenzio, A; Roberts, MC | 1 |
| Basilisco, G; Bianchi, PA; Bozzani, A; Camboni, G | 1 |
| Gaginella, TS; Kachur, JF; Morgan, DW | 1 |
| Isolauri, E; Vesikari, T | 1 |
| Dodge, JA; Hamdi, I | 1 |
| Clench, MH; Davis, RH; Mathias, JR; Sninsky, CA; Thomas, KD | 1 |
| Barina, W; Domschke, W; Hagel, J; Kachel, G; Meinhardt, M; Ruppin, H | 1 |
| Bitsura, JA; DuPont, HL; Ericsson, CD; Johnson, PC; Morgan, DR; Wood, LV | 1 |
| Basilisco, G; Bianchi, PA; Bozzani, A; Camboni, G; Conte, D; Penagini, R; Quatrini, M; Recchia, M | 1 |
| Bohn, M; Wienbeck, M | 1 |
| Chu, YH; Ren, MY; Song, GX; Zhang, L; Zhang, YJ | 1 |
| Sommers, DK; Steyn, AG; Van Wyk, M | 1 |
| Fasano, A; Ferola, A; Guandalini, S; Marchesano, G; Migliavacca, M; Rao, MC; Rubino, A | 1 |
| Bunjes, R; Krienke, EG; von Mühlendahl, KE | 1 |
| Heap, J; Macnair, A | 1 |
| Marcovitch, H | 1 |
| Friedli, G; Haenggeli, CA | 1 |
| Dreessen, MJ; Lemli, JA; Verhaeren, EH | 1 |
| Brown, BL; Merritt, JE; Tomlinson, S | 1 |
| Sato, M; Yamamoto, K; Yamashiro, Y | 1 |
| Contreras, E; Germany, A; Merino, A | 1 |
| Broadhead, R; Gangal, RN; Hendrickse, RG; Jaswal, OP; Owens, JR | 1 |
| Bloom, SR; Christofides, ND; Rees, WD; Sharpe, GR; Turnberg, LA | 1 |
| Candy, DC; Harries, JT; Sandhu, BK; Tripp, JH | 1 |
| Hardcastle, J; Hardcastle, PT; Read, NW; Redfern, JS | 1 |
| Farack, UM; Kautz, U; Loeschke, K | 1 |
| Giagnoni, G; Gori, E; Marabini, L; Parolaro, D; Sala, M; Senini, R | 1 |
| Harries, JT; Milla, PJ; Sandhu, BK | 1 |
| Casiraghi, L; Giagnoni, G; Gori, E; Parolaro, D; Revel, L; Sala, M; Senini, R | 1 |
| Milla, PJ; Phillips, AD; Sandhu, BK | 1 |
| Farack, UM; Loeschke, K | 1 |
| Barends, D; Cann, PA; Holdsworth, CD; Read, NW | 1 |
| Degryse, AD; Janssen, PA; Ooms, LA | 1 |
| Kassem, AS; Madkour, AA; Massoud, BZ; Mehanna, ZM | 1 |
| Grŭncharov, V | 1 |
| Appia, F; Chariot, J; De La Tour, J; Roze, C; Vaille, C | 1 |
| Singh, DS; Singh, NK; Srivastava, PK | 1 |
| Gould, RJ; Reynolds, IJ; Snyder, SH | 1 |
| Turnberg, LA | 1 |
| Higgs, NB; Hughes, S; Turnberg, LA | 2 |
| Bastidas, O; Bermudez, EL; Ramirez, MS | 1 |
| Caro-Paton Gómez, A; Casas Carnicero, J; Dueñas Laita, A; Fernández de la Gandara, F | 1 |
| Tan, SH | 2 |
| Slee, GL; Vinks, JA | 1 |
| Altaparmakov, I; Wienbeck, M | 1 |
| Jaecques, N | 1 |
| Fordtran, JS; Morawski, SG; Santa Ana, CA; Schiller, LR | 1 |
| Bergman, L; Djärv, L | 1 |
| Andersen, B; Gudmand-Høyer, E; Skovbjerg, H; Wille-Jørgensen, P | 1 |
| Candy, DC; Gregory, B; Harries, JT; Tripp, JH; Watt, J | 1 |
| Barbieri, C; Borzio, M; Caldara, R; Ferrari, C; Rampini, P; Romussi, M; Testori, GP | 1 |
| Harries, JT; Milla, PJ; Sandhu, BK; Tripp, JH | 1 |
| Nelson, R; Richmond, SW; Weaver, LT | 1 |
| Fleming, CR; Malagelada, JR; Remington, M; Zinsmeister, A | 1 |
| Hashimoto, M; Ishii, K; Motoyoshi, S; Nakamura, H; Sekine, Y; Shimizu, M; Suzuki, K; Yokoyama, Y | 1 |
| Martin, S | 1 |
| Pounder, RE; Shee, CD | 1 |
| Corbett, CL; Holdsworth, CD; Palmer, KR | 1 |
| Hill, GL; King, RF; Norton, T | 1 |
| Fleming, CR; Malagelada, JR; Remington, M | 1 |
| Ferenci, P; Lochs, H; Pötzi, R | 1 |
| Barber, DC; Duthie, HL; Read, M; Read, NW | 1 |
| Hashimoto, M; Miyazaki, H; Nambu, K | 1 |
| Aillaud, L; Barinagarrementería, R; Landa, L; Ramírez-Degollado, J | 1 |
| Flórez, J; Herranz, J; Luzuriaga, C; Sarralle, R | 1 |
| Gordin, A; Kekomäki, M; Salo, H; Vilkki, P | 1 |
| Barbieri, C; Caldara, R; Cambielli, M; Ferrari, C; Guslandi, M; Masci, E | 1 |
| Baker, GF; Segal, MB | 1 |
| Korey, A; Sellers, EM; Zilm, DH | 1 |
| Green, J; Jaffe, JH; Kanzler, M | 1 |
| Furuya-Meguro, ME; Hernández-Zamora, A; Montoya-Cabrera, MA; Palacios-Treviño, JL | 1 |
| Ashton, C; Gonsalves, S; Watson, J | 1 |
| Barry, JL; Bornet, F; Bruley des Varannes, S; Cloarec, D; El Oufir, L; Flourié, B; Galmiche, JP | 1 |
| Croci, T; Emonds-Alt, X; Landi, M; Le Fur, G; Maffrand, JP; Manara, L | 1 |
| Fischer, H; Gottschlich, R; Seelig, A | 1 |
| Capasso, F; Capasso, R; Izzo, AA; Mascolo, N; Pinto, L | 1 |
| Andrews, PL; Reynolds, DJ; Watson, JW; Woods, AJ; Zaman, S | 1 |
| Nozaki-Taguchi, N; Yaksh, TL | 1 |
| Aftab, MT; Ghayur, MN; Gilani, AH; Saify, ZS; Taqvi, SI | 1 |
| Barker, WM; Belanger, S; Cassel, JA; Conway-James, NC; DeHaven, RN; DeHaven-Hudkins, DL; Dolle, RE; Le Bourdonnec, B; Little, PJ; O'Neill, TJ; Wiant, DD | 1 |
| Aviello, G; Borrelli, F; Capasso, F; Capasso, R; Izzo, AA; Romano, B; Scalisi, C | 1 |
| Bidlack, JM; Dean, RL; Deaver, DR; Eyerman, D; Todtenkopf, MS; Turncliff, RZ | 1 |
| Bao, X; Jin, Y; Liu, D; Yang, Y | 1 |
| Egan, JA; Filer, CN; Nugent, RP | 1 |
| Budriesi, R; Caputo, L; Cavalluzzi, MM; Corazza, I; De Salvia, MA; Franchini, C; Gualdani, R; Lentini, G; Micucci, M; Milani, G; Piarulli, M; Quintieri, L; Rosato, A; Viale, M | 1 |
3 review(s) available for loperamide and piperidines
| Article | Year |
|---|---|
Loperamide: a review of its pharmacological properties and therapeutic efficacy in diarrhoea.
Topics: Acute Disease; Animals; Chronic Disease; Clinical Trials as Topic; Diarrhea; Gastrointestinal Motility; Humans; Loperamide; Narcotics; Piperidines | 1978 |
Safety and efficacy of loperamide.
Topics: Acute Disease; Clinical Trials as Topic; Diarrhea; Dose-Response Relationship, Drug; Humans; Loperamide; Nonprescription Drugs; Piperidines; Self Medication | 1990 |
Mechanisms of action of loperamide.
Topics: Absorption; Animals; Bacterial Toxins; Calcium Channel Blockers; Calmodulin; Chemical Phenomena; Chemistry; Endorphins; Gastrointestinal Motility; Humans; Kinetics; Loperamide; Piperidines; Prostaglandins; Tissue Distribution; Water-Electrolyte Balance | 1984 |
58 trial(s) available for loperamide and piperidines
| Article | Year |
|---|---|
Loperamide, a new antidiarrheal agent in the treatment of chronic diarrhea.
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Diarrhea; Female; Humans; Long-Term Care; Loperamide; Male; Piperidines; Placebos | 1978 |
Double-blind placebo-controlled study of loperamide (Imodium) in chronic diarrhoea caused by ileocolic disease or resection.
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Crohn Disease; Diarrhea; Female; Gastrointestinal Motility; Humans; Intestines; Loperamide; Male; Middle Aged; Piperidines | 1977 |
Effect of loperamide on fecal output and composition in well-established ileostomy and ileorectal anastomosis.
Topics: Adult; Aged; Bile Acids and Salts; Calcium; Chlorides; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Feces; Female; Humans; Ileostomy; Ileum; Loperamide; Male; Middle Aged; Piperidines; Placebos; Potassium; Rectum; Sodium; Water | 1977 |
A comparison of lomotil and imodium in acute non-specific diarrhoea.
Topics: Acute Disease; Adult; Clinical Trials as Topic; Diarrhea; Diphenoxylate; Female; Humans; Isonipecotic Acids; Loperamide; Male; Piperidines | 1977 |
Loperamide for diarrhea.
Topics: Adult; Biopharmaceutics; Child, Preschool; Clinical Trials as Topic; Diarrhea; Diphenoxylate; Double-Blind Method; Female; Humans; Loperamide; Male; Piperidines; Placebos; Pregnancy | 1977 |
Symptomatic treatment of acute self-limiting diarrhoea in adults.
Topics: Clinical Trials as Topic; Diarrhea; Drug Combinations; Humans; Kaolin; Loperamide; Morphine; Piperidines | 1977 |
Prostaglandin-induced diarrhoea treated with loperamide or diphenoxylate. A double-blind study.
Topics: Abortion, Induced; Adult; Blood Pressure; Body Temperature; Capsules; Chemical Phenomena; Chemistry; Clinical Trials as Topic; Diarrhea; Diphenoxylate; Double-Blind Method; Female; Heart Rate; Humans; Isonipecotic Acids; Loperamide; Piperidines; Placebos; Prostaglandins; Respiration; Time Factors | 1977 |
Loperamide: a review of its pharmacological properties and therapeutic efficacy in diarrhoea.
Topics: Acute Disease; Animals; Chronic Disease; Clinical Trials as Topic; Diarrhea; Gastrointestinal Motility; Humans; Loperamide; Narcotics; Piperidines | 1978 |
Long-term survey of the treatment of diarrhoea with loperamide.
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Drug Evaluation; Female; Humans; Isotonic Solutions; Loperamide; Male; Middle Aged; Naloxone; Piperidines; Pupil; Sodium Chloride; Time Factors | 1977 |
A double-blind trial of loperamide in the treatment of chronic diarrhoea.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Chronic Disease; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Female; Humans; Loperamide; Male; Middle Aged; Piperidines | 1979 |
Human pharmacokinetics and comparative bioavailability of loperamide hydrochloride.
Topics: Adult; Antibody Specificity; Biological Availability; Capsules; Half-Life; Humans; Kinetics; Loperamide; Male; Piperidines; Radioimmunoassay | 1979 |
Multicentre general practice comparison of loperamide and diphenoxylate with atropine in the treatment of acute diarrhoea in adults.
Topics: Acute Disease; Adolescent; Adult; Atropine; Diarrhea; Diphenoxylate; Drug Therapy, Combination; Humans; Isonipecotic Acids; Loperamide; Piperidines | 1979 |
Loperamide: a new antidiarrheal agent in the treatment of chronic diarrhea.
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Diarrhea; Female; Humans; Loperamide; Male; Middle Aged; Piperidines; Placebos | 1976 |
A double blind crossover comparison of loperamide with diphenoxylate in the symptomatic treatment of chronic diarrhea.
Topics: Adult; Chronic Disease; Clinical Trials as Topic; Diarrhea; Diphenoxylate; Feces; Female; Humans; Isonipecotic Acids; Loperamide; Male; Middle Aged; Piperidines | 1976 |
Loperamide in chronic diarrhea and after ileostomy: a placebo-controlled double-blind cross-over study.
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Colitis, Ulcerative; Colonic Diseases, Functional; Diarrhea; Female; Humans; Ileostomy; Loperamide; Male; Middle Aged; Piperidines | 1976 |
Loperamide in the symptomatic control of chronic diarrhoea. Double-blind placebo-controlled study.
Topics: Adult; Capsules; Chronic Disease; Clinical Trials as Topic; Diarrhea; Female; Humans; Loperamide; Middle Aged; Piperidines | 1975 |
Letter: Loperamide and ileostomy output.
Topics: Humans; Ileostomy; Loperamide; Piperidines | 1975 |
Acute diarrhoea in expatriates in Bangladesh.
Topics: Diarrhea; Drug Combinations; Drug Therapy, Combination; Electrolytes; Glucose; Humans; Loperamide; Male; Piperidines; Randomized Controlled Trials as Topic | 1990 |
Safety and efficacy of loperamide.
Topics: Acute Disease; Clinical Trials as Topic; Diarrhea; Dose-Response Relationship, Drug; Humans; Loperamide; Nonprescription Drugs; Piperidines; Self Medication | 1990 |
Comparative efficacy of loperamide hydrochloride and bismuth subsalicylate in the management of acute diarrhea.
Topics: Acute Disease; Adult; Bismuth; Clinical Trials as Topic; Diarrhea; Dose-Response Relationship, Drug; Female; Humans; Loperamide; Male; Nonprescription Drugs; Organometallic Compounds; Piperidines; Salicylates | 1990 |
A randomized, open-label comparison of nonprescription loperamide and attapulgite in the symptomatic treatment of acute diarrhea.
Topics: Acute Disease; Adult; Diarrhea; Dose-Response Relationship, Drug; Female; Humans; Loperamide; Magnesium; Magnesium Compounds; Male; Nonprescription Drugs; Piperidines; Randomized Controlled Trials as Topic; Silicon; Silicon Compounds | 1990 |
Loperamide (imodium)--clinical trial.
Topics: Acute Disease; Chronic Disease; Clinical Trials as Topic; Diarrhea; Humans; Loperamide; Piperidines | 1990 |
Effect of increasing oral doses of loperamide on gallbladder motility in man.
Topics: Adult; Cholecystokinin; Dose-Response Relationship, Drug; Female; Gallbladder; Humans; Infusions, Intravenous; Loperamide; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Radioimmunoassay; Ultrasonics | 1990 |
Treatment of traveler's diarrhea with sulfamethoxazole and trimethoprim and loperamide.
Topics: Adult; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Fluid Therapy; Humans; Loperamide; Mexico; Piperidines; Prospective Studies; Randomized Controlled Trials as Topic; Travel; Trimethoprim, Sulfamethoxazole Drug Combination; United States | 1990 |
Loperamide in acute diarrhoea in childhood: results of a double blind, placebo controlled clinical trial.
Topics: Child, Preschool; Clinical Trials as Topic; Combined Modality Therapy; Diarrhea; Dose-Response Relationship, Drug; Double-Blind Method; Fluid Therapy; Humans; Infant; Loperamide; Piperidines; Saudi Arabia | 1987 |
Double blind trial of loperamide for treating acute watery diarrhoea in expatriates in Bangladesh.
Topics: Acute Disease; Adult; Aged; Bangladesh; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Europe; Female; Humans; Loperamide; Male; Middle Aged; North America; Piperidines; Random Allocation; Travel | 1989 |
The effect of loperamide on bowel habits and anal sphincter function in patients with ileoanal anastomosis.
Topics: Adult; Anal Canal; Anastomosis, Surgical; Clinical Trials as Topic; Defecation; Female; Gastrointestinal Motility; Humans; Ileum; Loperamide; Male; Piperidines | 1989 |
Loperamide, an opiate analog, differently modifies the adrenocorticotropin responses to corticotropin-releasing hormone and lysine vasopressin in patients with Addison's disease.
Topics: Addison Disease; Adrenocorticotropic Hormone; Adult; Aged; Corticotropin-Releasing Hormone; Double-Blind Method; Drug Interactions; Female; Humans; Loperamide; Lypressin; Male; Middle Aged; Piperidines; Random Allocation | 1988 |
Loperamide, an opiate analogue, inhibits plasma ACTH levels in patients with Addison's disease.
Topics: Addison Disease; Adrenocorticotropic Hormone; Adult; Aged; beta-Lipotropin; Depression, Chemical; Female; Humans; Loperamide; Male; Middle Aged; Piperidines; Random Allocation | 1986 |
Treatment of chronic diarrhoea: loperamide versus ispaghula husk and calcium.
Topics: Adult; Aged; Calcium; Chronic Disease; Clinical Trials as Topic; Diarrhea; Drug Combinations; Female; Humans; Loperamide; Male; Middle Aged; Piperidines; Psyllium; Random Allocation | 1988 |
Loperamide in treatment of irritable bowel syndrome--a double-blind placebo controlled study.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Colonic Diseases, Functional; Diarrhea; Double-Blind Method; Female; Humans; Loperamide; Male; Middle Aged; Patient Compliance; Piperidines; Random Allocation | 1987 |
Loperamide treatment of the irritable bowel syndrome.
Topics: Clinical Trials as Topic; Colic; Colonic Diseases, Functional; Double-Blind Method; Humans; Loperamide; Piperidines; Random Allocation | 1987 |
[Indications for loperamide in acute infantile diarrhea. Randomized double-blind study].
Topics: Adult; Child, Preschool; Clinical Trials as Topic; Diarrhea, Infantile; Double-Blind Method; Humans; Infant, Newborn; Loperamide; Piperidines; Placebos; Random Allocation | 1987 |
Symptomatic treatment of acute infectious diarrhoea: loperamide versus placebo in a double-blind trial.
Topics: Acute Disease; Adolescent; Adult; Aged; Bacterial Infections; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Female; Humans; Loperamide; Male; Middle Aged; Piperidines; Time Factors | 1986 |
[Effectiveness of imodium in the treatment of patients with peptic ulcer and chronic gastroduodenitis associated with functional intestinal disorders].
Topics: Antidiarrheals; Clinical Trials as Topic; Diarrhea; Duodenitis; Gastroenteritis; Humans; Loperamide; Peptic Ulcer; Piperidines | 1986 |
A multicenter double-blind controlled trial comparing lidamidine HCl and loperamide in the symptomatic treatment of acute diarrhoea.
Topics: Acute Disease; Antidiarrheals; Clinical Trials as Topic; Diarrhea; Double-Blind Method; Female; Humans; Loperamide; Male; Phenylurea Compounds; Piperidines; Random Allocation | 1986 |
[Effect of loperamide on fecal flora of children with severe prolonged diarrhea].
Topics: Child, Preschool; Diarrhea, Infantile; Feces; Humans; Infant; Loperamide; Piperidines | 1987 |
Oral naloxone antagonizes loperamide-induced delay of orocecal transit.
Topics: Administration, Oral; Adult; Breath Tests; Double-Blind Method; Drug Administration Schedule; Female; Gastrointestinal Motility; Humans; Hydrogen; Lactulose; Loperamide; Male; Mouth; Naloxone; Piperidines; Random Allocation | 1987 |
A comparative trial of cholestyramine and loperamide for acute diarrhoea in infants treated as outpatients.
Topics: Acute Disease; Ambulatory Care; Child, Preschool; Cholestyramine Resin; Clinical Trials as Topic; Diarrhea; Diarrhea, Infantile; Fluid Therapy; Humans; Infant; Loperamide; Piperidines; Water-Electrolyte Balance | 1985 |
Effect of lidamidine hydrochloride and loperamide on gastric emptying and transit of the small intestine. A double-blind study.
Topics: Adolescent; Adult; Antidiarrheals; Double-Blind Method; Gastric Emptying; Gastrointestinal Motility; Humans; Intestinal Absorption; Intestine, Small; Loperamide; Male; Phenylurea Compounds; Piperidines; Random Allocation; Water-Electrolyte Balance | 1986 |
Human intestinal motor activity and transport: effects of a synthetic opiate.
Topics: Adult; Biological Transport; Colon; Diarrhea; Gastrointestinal Motility; Humans; Ileum; Intestinal Absorption; Jejunum; Loperamide; Male; Manometry; Piperidines; Stimulation, Chemical; Water-Electrolyte Balance | 1986 |
Comparison of loperamide with bismuth subsalicylate for the treatment of acute travelers' diarrhea.
Topics: Acute Disease; Adult; Antidiarrheals; Bismuth; Diarrhea; Humans; Latin America; Loperamide; Organometallic Compounds; Piperidines; Salicylates; Travel; United States | 1986 |
Loperamide in the treatment of acute gastroenteritis in early childhood. Report of a two centre, double-blind, controlled clinical trial.
Topics: Body Weight; Child, Preschool; Double-Blind Method; Drug Evaluation; Escherichia coli; Female; Gastroenteritis; Humans; Infant; Length of Stay; Loperamide; Male; Piperidines; Prostaglandins E; Rotavirus | 1981 |
The effects of an opiate agonist and antagonist on the human upper gastrointestinal tract.
Topics: Adult; Amylases; Bile Acids and Salts; Digestive System; Digestive System Physiological Phenomena; Duodenum; Endorphins; Gastric Acid; Gastrointestinal Motility; Humans; Loperamide; Motilin; Naloxone; Piperidines | 1983 |
Role of loperamide and placebo in management of irritable bowel syndrome (IBS).
Topics: Adult; Clinical Trials as Topic; Colonic Diseases, Functional; Consumer Behavior; Diarrhea; Double-Blind Method; Female; Follow-Up Studies; Food; Gastric Emptying; Humans; Intestine, Small; Intestines; Loperamide; Male; Middle Aged; Piperidines; Placebos; Time Factors | 1984 |
Loperamide in acute childhood diarrhoea: a double blind controlled trial.
Topics: Clinical Trials as Topic; Dehydration; Diarrhea, Infantile; Double-Blind Method; Feces; Humans; Infant; Loperamide; Male; Piperidines; Vomiting | 1983 |
[Results of a clinical study of the Hungarian preparation Imodium].
Topics: Adult; Aged; Antidiarrheals; Capsules; Clinical Trials as Topic; Defecation; Diarrhea; Female; Humans; Loperamide; Male; Middle Aged; Piperidines; Solutions; Time Factors | 1984 |
Loperamide in acute diarrhoea in childhood: results of a double blind, placebo controlled multicentre clinical trial. Diarrhoeal Diseases Study Group (UK).
Topics: Acute Disease; Body Weight; Child, Preschool; Clinical Trials as Topic; Combined Modality Therapy; Diarrhea; Double-Blind Method; Feces; Fluid Therapy; Humans; Infant; Loperamide; Piperidines; Time Factors | 1984 |
A comparative study of loperamide and diphenoxylate in the treatment of chronic diarrhoea caused by intestinal resection.
Topics: Adult; Aged; Chronic Disease; Clinical Trials as Topic; Crohn Disease; Diarrhea; Diphenoxylate; Double-Blind Method; Female; Humans; Intestines; Isonipecotic Acids; Loperamide; Male; Middle Aged; Piperidines; Postoperative Complications; Random Allocation | 1981 |
Diarrhoea following jejuno-ileostomy for morbid obesity. A randomised trial of loperamide and diphenoxylate.
Topics: Adult; Clinical Trials as Topic; Diarrhea; Diphenoxylate; Female; Humans; Ileum; Isonipecotic Acids; Jejunum; Loperamide; Male; Obesity; Piperidines; Postoperative Complications; Random Allocation | 1982 |
Loperamide modifies Escherichia coli, heat-stable enterotoxin-induced intestinal secretion.
Topics: Animals; Clinical Trials as Topic; Enterotoxins; Escherichia coli; Hot Temperature; Intestinal Mucosa; Loperamide; Mice; Piperidines; Random Allocation; Time Factors | 1982 |
Abnormalities in gastrointestinal motor activity in patients with short bowels: effect of a synthetic opiate.
Topics: Adult; Aged; Eating; Fasting; Female; Gastrointestinal Motility; Humans; Loperamide; Malabsorption Syndromes; Male; Middle Aged; Motor Neurons; Piperidines; Pressure; Short Bowel Syndrome; Time Factors | 1983 |
Loperamide, diphenoxylate, and codeine phosphate in chronic diarrhoea.
Topics: Chronic Disease; Clinical Trials as Topic; Codeine; Diarrhea; Diphenoxylate; Double-Blind Method; Humans; Isonipecotic Acids; Loperamide; Piperidines | 1980 |
Double-blind cross-over study comparing loperamide, codeine and diphenoxylate in the treatment of chronic diarrhea.
Topics: Antidiarrheals; Chronic Disease; Clinical Trials as Topic; Codeine; Diarrhea; Diphenoxylate; Double-Blind Method; Humans; Isonipecotic Acids; Loperamide; Piperidines; Random Allocation; Time Factors | 1980 |
A double-blind crossover study of the effect of loperamide hydrochloride and codeine phosphate on ileostomy output.
Topics: Adult; Aged; Body Weight; Clinical Trials as Topic; Codeine; Diarrhea; Double-Blind Method; Electrolytes; Female; Humans; Ileostomy; Loperamide; Male; Middle Aged; Nausea; Piperidines; Postoperative Complications; Potassium; Sodium | 1982 |
Effects of loperamide on anal sphincter function in patients complaining of chronic diarrhea with fecal incontinence and urgency.
Topics: Adult; Aged; Anal Canal; Diarrhea; Fecal Incontinence; Female; Humans; Loperamide; Male; Manometry; Middle Aged; Piperidines; Rectum | 1982 |
Loperamide as a symptomatic treatment in pediatric surgery: a double-blind cross-over study.
Topics: Adolescent; Child; Child, Preschool; Diarrhea; Dose-Response Relationship, Drug; Double-Blind Method; Fecal Incontinence; Female; Humans; Loperamide; Male; Piperidines; Postoperative Complications | 1981 |
Abuse potential of loperamide.
Topics: Adult; Codeine; Humans; Loperamide; Male; Naloxone; Piperidines; Pupil; Substance-Related Disorders | 1980 |
165 other study(ies) available for loperamide and piperidines
| Article | Year |
|---|---|
Loperamide binding to opiate receptor sites of brain and myenteric plexus.
Topics: Analgesics, Opioid; Animals; Brain; Electric Stimulation; Female; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Loperamide; Male; Morphine; Muscle Contraction; Myenteric Plexus; Naloxone; Piperidines; Reaction Time; Receptors, Opioid | 1976 |
[Pharmacological studies of loperamide, an anti-diarrheal agent. I. Effects on diarrhea induced by castor oil and prostaglandin E. (author's transl)].
Topics: Analgesics; Analgesics, Opioid; Anesthetics, Local; Animals; Antidiarrheals; Castor Oil; Diarrhea; Dose-Response Relationship, Drug; Gastrointestinal Motility; Lethal Dose 50; Loperamide; Male; Piperidines; Prostaglandins E; Rats; Time Factors | 1978 |
Loperamide inhibits cholera-toxin-induced small-intestinal secretion.
Topics: Animals; Cholera Toxin; Diarrhea; Electrolytes; Jejunum; Loperamide; Male; Piperidines; Rats; Water | 1979 |
Loperamide and acute infective diarrhoea in children.
Topics: Child, Preschool; Diarrhea, Infantile; Humans; Infant; Loperamide; Piperidines | 1979 |
Loperamide and acute infective diarrhoea in children.
Topics: Acute Disease; Child; Child, Preschool; Diarrhea; Diphenoxylate; Dysentery, Bacillary; Humans; Infant; Loperamide; Piperidines | 1979 |
Dependence potential of loperamide studied in rhesus monkeys.
Topics: Administration, Oral; Animals; Behavior, Animal; Female; Haplorhini; Humans; Injections, Intravenous; Injections, Subcutaneous; Loperamide; Macaca mulatta; Male; Piperidines; Self Administration; Substance Withdrawal Syndrome; Substance-Related Disorders | 1979 |
Interaction of loperamide with [3H]naloxone binding sites in guinea pig brain and myenteric plexus.
Topics: Animals; Binding Sites; Brain; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; Ileum; In Vitro Techniques; Loperamide; Male; Morphine; Muscle Contraction; Muscle, Smooth; Myenteric Plexus; Naloxone; Piperidines; Receptors, Opioid | 1977 |
[Loperamide in the treatment of chronic diarrhea].
Topics: Adolescent; Adult; Aged; Chronic Disease; Diarrhea; Female; Humans; Loperamide; Male; Middle Aged; Piperidines | 1979 |
[The effects of loperamide hydrochloride on the bowel movements of healthy persons. Estimation of CD50 with the up-and-down method, and pharmacokinetic analysis of blood concentration of the drug (author's transl)].
Topics: Adult; Constipation; Gastrointestinal Motility; Humans; Loperamide; Male; Piperidines | 1979 |
[Results of treating chronic diarrhea with loperamide in patients with functional intestinal disorders].
Topics: Adult; Chronic Disease; Colonic Diseases, Functional; Diarrhea; Female; Humans; Intestinal Diseases; Loperamide; Male; Middle Aged; Piperidines | 1979 |
Distribution of loperamide in the intestinal wall.
Topics: Animals; Guinea Pigs; Ileum; In Vitro Techniques; Intestinal Mucosa; Loperamide; Muscle, Smooth; Myenteric Plexus; Piperidines; Tissue Distribution | 1979 |
Effects of loperamide on the guinea pig taenia coli.
Topics: Acetylcholine; Animals; Colon; Drug Interactions; Electric Stimulation; Female; Guinea Pigs; In Vitro Techniques; Loperamide; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Nicotine; Piperidines; Serotonin | 1979 |
Metabolites of loperamide in rats.
Topics: Animals; Chemical Fractionation; Chemical Phenomena; Chemistry; Feces; Loperamide; Male; Mass Spectrometry; Piperidines; Rats | 1979 |
[Diarrhea].
Topics: Diarrhea; Humans; Loperamide; Piperidines | 1979 |
Naloxone inhibits the anti-diarrhoeal activity of loperamide.
Topics: Animals; Diarrhea; Loperamide; Male; Naloxone; Piperidines; Prostaglandins E; Rats | 1979 |
Disposition and metabolism of [14C]loperamide in rats.
Topics: Animals; Bile; Biotransformation; Carbon Radioisotopes; Feces; In Vitro Techniques; Intestinal Absorption; Liver; Loperamide; Male; Piperidines; Protein Binding; Rats; Time Factors | 1979 |
[Effects of loperamide on the gastric and intestinal motilities in the guinea pig and dog (author's transl)].
Topics: Animals; Atropine; Colon; Dogs; Gastrointestinal Motility; Guinea Pigs; Injections, Intravenous; Intestine, Small; Loperamide; Morphine; Piperidines | 1977 |
On the antidiarrhoeal and analgesic properties of diphenoxylate, difenoxine and loperamide in mice and rats.
Topics: Analgesics; Animals; Antidiarrheals; Diphenoxylate; Isonipecotic Acids; Loperamide; Male; Meperidine; Mice; Piperidines; Rats | 1977 |
Loperamide in patients with radiotherapy-induced diarrhoea.
Topics: Abdominal Neoplasms; Adult; Aged; Diarrhea; Female; Humans; Loperamide; Male; Middle Aged; Piperidines; Radiotherapy | 1978 |
In vivo antimotility and antidiarrheal activity of lidamidine hydrochloride (WHR-1142A), a novel antidiarrheal agent. Comparison with diphenoxylate and loperamide.
Topics: Amidines; Animals; Antidiarrheals; Carbachol; Charcoal; Cholera Toxin; Diarrhea; Diphenoxylate; Feces; Gastrointestinal Motility; Isonipecotic Acids; Loperamide; Male; Piperidines; Prostaglandins E; Rats; Serotonin; Stomach | 1978 |
The use of loperamide for treatment of "difficult to manage" chronic diarrhoea in adults.
Topics: Adult; Chronic Disease; Colitis; Diarrhea; Diverticulitis, Colonic; Enteritis; Humans; Loperamide; Piperidines | 1977 |
[Studies using loperamide in patients with diarrhea following telecobalt irradiation of malignant abdominal tumors (author's transl)].
Topics: Abdominal Neoplasms; Adult; Aged; Diarrhea; Female; Humans; Loperamide; Middle Aged; Piperidines; Radiation Injuries; Radioisotope Teletherapy | 1978 |
The use of loperamide to regulate peristalsis and improve bowel control: a preliminary report.
Topics: Child; Fecal Incontinence; Female; Gastrointestinal Motility; Humans; Infant; Intestine, Small; Loperamide; Lumbosacral Plexus; Megacolon; Peristalsis; Piperidines; Rectum; Spina Bifida Occulta | 1978 |
[Pharmacological studies of loperamide, an anti-diarrheal agent. II. Effects on peristalsis of the small intestine and colon in guinea pigs (author's transl)].
Topics: Animals; Atropine; Colon; Depression, Chemical; Dose-Response Relationship, Drug; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Intestine, Small; Loperamide; Male; Morphine; Peristalsis; Piperidines; Time Factors | 1978 |
The control of acute diarrhea in a large industrial plant.
Topics: Absenteeism; Acute Disease; Adult; Automobiles; Diarrhea; Female; Humans; Loperamide; Male; Occupational Medicine; Peristalsis; Piperidines | 1978 |
[Pharmacological studies of loperamide, an anti-diarrheal agent. III. Interaction between loperamide and various agonists in the guinea pig intestine (author's transl)].
Topics: Acetylcholine; Animals; Antidiarrheals; Barium; Bradykinin; Calcium; Guinea Pigs; Histamine Antagonists; Ileum; In Vitro Techniques; Intestines; Loperamide; Male; Muscle Contraction; Muscle, Smooth; Nicotine; Physical Stimulation; Piperidines; Prostaglandins E; Serotonin Antagonists | 1978 |
Probable interaction of loperamide and cholestyramine.
Topics: Cholestyramine Resin; Drug Interactions; Humans; Ileostomy; Intestinal Absorption; Loperamide; Male; Middle Aged; Piperidines; Postoperative Complications | 1978 |
Effects of loperamide on acetylcholine and prostaglandin release from isolated guinea pig ileum.
Topics: Acetylcholine; Animals; Depression, Chemical; Guinea Pigs; Ileum; In Vitro Techniques; Intestinal Mucosa; Loperamide; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Parasympatholytics; Piperidines; Prostaglandins | 1978 |
Interaction of loperamide and diphenoxylate with ethanol and methohexital.
Topics: Animals; Diphenoxylate; Drug Interactions; Ethanol; Hypnotics and Sedatives; Isonipecotic Acids; Loperamide; Male; Methohexital; Mice; Piperidines; Rats; Reflex | 1978 |
Toxic megacolon associated with loperamide therapy.
Topics: Adult; Chronic Disease; Colitis, Ulcerative; Humans; Loperamide; Male; Megacolon, Toxic; Peristalsis; Piperidines | 1979 |
The effect of loperamide on prostaglandin induced diarrhoea in rat and man.
Topics: Abortion, Induced; Animals; Cricetinae; Diarrhea; Drug Evaluation, Preclinical; Female; Humans; Loperamide; Male; Muscle Contraction; Muscle, Smooth; Piperidines; Pregnancy; Prostaglandin Antagonists; Prostaglandins E; Prostaglandins F; Rats | 1977 |
[Imodium, new symptomatic treatment of diarrhea].
Topics: Diarrhea; Humans; Loperamide; Piperidines | 1977 |
[Loperamide in acute diarrhea (author's transl)].
Topics: Acute Disease; Adolescent; Adult; Aged; Diarrhea; Drug Evaluation; Female; Humans; Loperamide; Male; Middle Aged; Piperidines; Tablets | 1977 |
Loperamide and other antidiarrhoeal drugs.
Topics: Antidiarrheals; Diarrhea; Humans; Loperamide; Piperidines | 1977 |
Radioimmunoassay of the antidiarrhoeal loperamide.
Topics: Antibody Specificity; Glucuronates; Humans; Loperamide; Male; Piperidines; Radioimmunoassay | 1977 |
[Effects of loperamide on the motility of the isolated intestine in guinea pigs, rats and dogs (author's transl)].
Topics: Action Potentials; Animals; Colon; Dogs; Gastrointestinal Motility; Guinea Pigs; Ileum; In Vitro Techniques; Intestine, Small; Loperamide; Membrane Potentials; Piperidines; Rats | 1977 |
[A new symptomatic treatment of diarrhea].
Topics: Child; Child, Preschool; Diarrhea; Drug Evaluation; Humans; Infant; Infant, Newborn; Loperamide; Piperidines | 1976 |
Letter: Loperamide in treatment of persistent diarrhoea in children.
Topics: Child, Preschool; Diarrhea; Humans; Infant; Loperamide; Piperidines | 1975 |
Loperamide antagonism of castor oil-induced diarrhea in rats: a quantitative study.
Topics: Animals; Body Weight; Castor Oil; Diarrhea; Feces; Female; Loperamide; Piperidines; Rats; Time Factors | 1975 |
Influence of cisapride, metoclopramide and loperamide on gastric emptying of normal volunteers as measured by means of the area under the curve of the cumulative fraction absorbed-time profiles of paracetamol.
Topics: Acetaminophen; Adult; Biological Availability; Cisapride; Gastric Emptying; Humans; Loperamide; Male; Metoclopramide; Piperidines; Serotonin Antagonists | 1992 |
Loperamide poisoning in children.
Topics: Child, Preschool; Developing Countries; Female; Humans; Infant; Intestinal Obstruction; Loperamide; Male; Pakistan; Piperidines; Product Surveillance, Postmarketing | 1990 |
Small intestinal amyogenesia and dysmyogenesia induced by morphine and loperamide.
Topics: Animals; Atropine; Dogs; Female; Gastrointestinal Motility; Hexamethonium; Hexamethonium Compounds; Intestine, Small; Loperamide; Male; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Piperidines | 1990 |
Loperamide poisoning in children.
Topics: Age Factors; Child, Preschool; Developing Countries; Humans; Infant; Loperamide; Pakistan; Piperidines | 1990 |
Withdrawal of loperamide drops.
Topics: Diarrhea; Humans; Infant; Loperamide; Pakistan; Piperidines; Product Surveillance, Postmarketing | 1990 |
Autoradiographic demonstration of [3H] loperamide binding to opioid receptors in rat and human small intestine.
Topics: Animals; Autoradiography; Humans; In Vitro Techniques; Intestine, Small; Loperamide; Piperidines; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Tissue Distribution | 1990 |
Naloxone-insensitive transport effects of loperamide in guinea-pig gallbladder epithelium.
Topics: Alprostadil; Animals; Bicarbonates; Biological Transport; Electrophysiology; Enkephalin, Methionine; Epithelium; Gallbladder; Guinea Pigs; In Vitro Techniques; Intestinal Absorption; Loperamide; Male; Naloxone; Piperidines; Receptors, Opioid; Sodium; Sodium Radioisotopes | 1990 |
Normalization of small intestinal propulsion with loperamide-like antidiarrheals in rats.
Topics: Analgesics; Animals; Antidiarrheals; Castor Oil; Gastrointestinal Motility; Intestine, Small; Loperamide; Male; Pain Measurement; Paraffin; Piperidines; Rats; Rats, Inbred Strains | 1990 |
Effect of loperamide on stool output and duration of acute infectious diarrhea in infants.
Topics: Administration, Oral; Diarrhea, Infantile; Drug Evaluation; Feces; Fluid Therapy; Humans; Infant; Loperamide; Male; Piperidines | 1990 |
[Small intestinal perforation as complication of loperamide treatment of Salmonella typhimurium infection].
Topics: Adolescent; Female; Humans; Ileal Diseases; Intestinal Perforation; Loperamide; Piperidines; Salmonella Food Poisoning | 1990 |
[Diet and loperamide are better than norfloxacin in tourist diarrhea].
Topics: Diarrhea; Humans; Loperamide; Norfloxacin; Piperidines; Travel | 1990 |
Secretagogue-induced changes in membrane calcium permeability in chicken and chinchilla ileal mucosa. Selective inhibition by loperamide.
Topics: Amiloride; Animals; Bombesin; Calcium; Carbachol; Carrier Proteins; Cell Membrane Permeability; Chickens; Chinchilla; Dose-Response Relationship, Drug; Gallopamil; Ileum; Intestinal Mucosa; Loperamide; Neurotensin; Piperidines; Serotonin; Sodium-Hydrogen Exchangers; Substance P; Trifluoperazine | 1986 |
Effects of the opiate agonist loperamide on pituitary-adrenal function in patients with suspected hypercortisolism.
Topics: Adrenocortical Hyperfunction; Adrenocorticotropic Hormone; Adult; Child; Dexamethasone; Female; Humans; Hydrocortisone; Loperamide; Male; Middle Aged; Piperidines; Pituitary-Adrenal System | 1989 |
Self-prescribing and promotion of antidiarrhoeal drugs.
Topics: Advertising; Diarrhea; Humans; Loperamide; Nonprescription Drugs; Piperidines; Self Medication | 1989 |
Characterization of the antidiarrhoeal loperamide by gas chromatography-mass spectrometry and application of the Hofmann degradation and Cope elimination reaction.
Topics: Antidiarrheals; Chemistry, Organic; Gas Chromatography-Mass Spectrometry; Humans; Loperamide; Organic Chemistry Phenomena; Piperidines | 1989 |
The effect of loperamide on the thermal behavior of dimyristoylphosphatidylcholine large unilamellar vesicles.
Topics: Dimyristoylphosphatidylcholine; Light; Loperamide; Membrane Fluidity; Membrane Lipids; Membranes, Artificial; Osmotic Pressure; Piperidines; Scattering, Radiation; Spectrophotometry, Infrared; Thermodynamics | 1989 |
Inhibition by loperamide of mucus secretion in the rat colon in vivo.
Topics: Animals; Body Fluids; Colon; Deoxycholic Acid; Dinoprostone; Female; Intestinal Mucosa; Loperamide; Mucus; Piperidines; Potassium; Rats; Rats, Inbred Strains; Sodium | 1989 |
Moderation of urinary and faecal incontinence with loperamide.
Topics: Aged; Fecal Incontinence; Female; Humans; Hungary; Loperamide; Male; Middle Aged; Piperidines; Urinary Incontinence | 1989 |
[Imodium for chronic diarrhea. Improving the quality of life. Report of the 44th meeting of the German Society for Digestive and Metabolic Diseases, 28 September 1989].
Topics: Chronic Disease; Diarrhea; Humans; Loperamide; Piperidines; Quality of Life | 1989 |
Dinner with De Quincey. Loperamide overdose.
Topics: History, 16th Century; History, 19th Century; Loperamide; Opioid-Related Disorders; Opium; Piperidines | 1989 |
Effect of metoclopramide, bethanechol, and loperamide on gastric residence time, gastric emptying, and mouth-to-cecum transit time.
Topics: Adolescent; Adult; Bethanechol Compounds; Gastric Emptying; Gastrointestinal Motility; Gastrointestinal Transit; Humans; Loperamide; Male; Metoclopramide; Piperidines | 1989 |
Selective blockage of cell membrane K conductance by an antisecretory agent in guinea-pig gallbladder epithelium.
Topics: Animals; Bicarbonates; Cell Membrane; Cell Membrane Permeability; Electric Conductivity; Epithelial Cells; Epithelium; Gallbladder; Guinea Pigs; Loperamide; Male; Membrane Potentials; Microelectrodes; Piperidines; Potassium | 1989 |
Central vs. peripheral mediation of opioid effects on alcohol consumption in free-feeding rats.
Topics: Alcohol Drinking; Animals; Dose-Response Relationship, Drug; Drinking Behavior; Drug Interactions; Loperamide; Male; Morphine; Naltrexone; Narcotic Antagonists; Piperidines; Polysorbates; Quaternary Ammonium Compounds; Rats; Rats, Inbred Strains; Time Factors | 1989 |
Loperamide--an opiate receptor agonist with gastrointestinal motility effects.
Topics: Gastrointestinal Motility; Humans; Kinetics; Loperamide; Piperidines; Receptors, Opioid | 1987 |
Inhibition of brush-border membrane Na+-H+ exchanger by loperamide.
Topics: Amiloride; Carrier Proteins; Drug Interactions; Female; Humans; Kinetics; Loperamide; Microvilli; Naloxone; Piperidines; Placenta; Reference Values; Sodium-Hydrogen Exchangers | 1987 |
Loperamide modifies but does not block the corticotropin-releasing hormone-induced ACTH response in patients with Addison's disease.
Topics: Addison Disease; Adrenocorticotropic Hormone; Adult; Aged; Corticotropin-Releasing Hormone; Female; Humans; Kinetics; Loperamide; Male; Middle Aged; Piperidines | 1987 |
Calmodulin-mediated effects of loperamide on chloride transport by brush border membrane vesicles from human ileum.
Topics: Biological Transport; Calcium; Calmodulin; Carrier Proteins; Chloride-Bicarbonate Antiporters; Chlorides; Humans; Ileum; In Vitro Techniques; Loperamide; Microvilli; Piperidines; Sodium; Sodium Chloride Symporters; Sodium-Hydrogen Exchangers; Symporters | 1988 |
Opioid and non-opioid actions of loperamide on cholinergic nerve function in human isolated colon.
Topics: Acetylcholine; Action Potentials; Calcium; Colon; Humans; In Vitro Techniques; Loperamide; Morphine; Muscle Contraction; Muscle, Smooth; Naloxone; Parasympathetic Nervous System; Piperidines; Receptors, Opioid | 1988 |
Action of loperamide on neuronally mediated and Ca2+- or cAMP-mediated secretion in rat colon.
Topics: Animals; Calcium; Carbachol; Colforsin; Colon; Cyclic AMP; Electric Stimulation; In Vitro Techniques; Intestinal Mucosa; Loperamide; Male; Morphine; Neurons; Piperidines; Rats; Rats, Inbred Strains; Trifluoperazine; Verapamil | 1988 |
Vagally mediated reflex and cardiac slowing induced by loperamide in rats.
Topics: Animals; Atropine; Benzomorphans; Blood Pressure; Heart Rate; Loperamide; Male; Naloxone; Narcotic Antagonists; Piperidines; Rats; Rats, Inbred Strains; Receptors, Opioid; Reflex; Vagus Nerve | 1985 |
Loperamide toxicity in a child after a single dose.
Topics: Diarrhea, Infantile; Female; Humans; Infant; Loperamide; Piperidines | 1987 |
[Effects of loperamide on the fecal flora in children in severe diarrheas].
Topics: Child, Preschool; Diarrhea, Infantile; Electrolytes; Enterobacteriaceae; Enterococcus faecalis; Escherichia coli; Feces; Humans; Infant; Loperamide; Piperidines; Pseudomonas; Staphylococcus | 1987 |
Effects of theophylline, choleragen and loperamide on rabbit ileal fluid and electrolyte transport in vitro.
Topics: Animals; Body Fluids; Bromides; Chlorides; Cholera Toxin; Electrolytes; Ileum; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Loperamide; Male; Mannitol; Osmolar Concentration; Piperidines; Rabbits; Theophylline | 1987 |
[Effect of imodium on the evacuatory function of the gastric stump and the small intestine in patients with the dumping syndrome].
Topics: Antidiarrheals; Dumping Syndrome; Female; Gastric Emptying; Intestine, Small; Loperamide; Male; Piperidines | 1988 |
High-performance liquid chromatographic determination of loperamide hydrochloride in pharmaceutical preparations.
Topics: Capsules; Chromatography, High Pressure Liquid; Loperamide; Piperidines; Reference Standards; Solutions; Spectrophotometry, Ultraviolet; Tablets | 1988 |
[Treatment of the drug-induced dyspeptic syndrome].
Topics: Antineoplastic Agents; Diarrhea; Humans; Loperamide; Piperidines | 1988 |
Solid state characterization and solubility enhancement of loperamide hydrochloride.
Topics: Chemistry, Pharmaceutical; Loperamide; Piperidines; Solubility | 1988 |
Effect of codeine and loperamide on upper intestinal transit and absorption in normal subjects and patients with postvagotomy diarrhoea.
Topics: Adult; Aged; Chronic Disease; Codeine; Diarrhea; Female; Gastrointestinal Transit; Glucose; Humans; Intestinal Absorption; Loperamide; Male; Middle Aged; Piperidines; Vagotomy | 1988 |
Use of Imodium in neurotic diarrhoeas.
Topics: Adult; Aged; Diarrhea; Female; Humans; Loperamide; Male; Middle Aged; Neurotic Disorders; Piperidines | 1987 |
Examination of Imodium in patients suffering from acute and chronic diarrhoea.
Topics: Acute Disease; Adolescent; Adult; Aged; Chronic Disease; Diarrhea; Female; Humans; Loperamide; Male; Middle Aged; Piperidines | 1986 |
Treatment of diarrhoeas of gynaecological patients with Imodium.
Topics: Adolescent; Adult; Diarrhea; Female; Humans; Loperamide; Middle Aged; Piperidines | 1987 |
[Effect of loperamide on the emptying of the gallbladder induced by caerulein].
Topics: Adult; Ceruletide; Gallbladder; Humans; Loperamide; Male; Piperidines | 1987 |
The influence of morphine, loperamide and naloxone on gallbladder response to prostaglandin E2 in the anaesthetized cat.
Topics: Animals; Cats; Cholecystitis; Dinoprostone; Female; Gallbladder; Loperamide; Male; Morphine; Muscle Contraction; Naloxone; Perfusion; Piperidines; Prostaglandins E; Water-Electrolyte Balance | 1986 |
Loperamide associated necrotising enterocolitis.
Topics: Enterocolitis, Pseudomembranous; Female; Humans; Infant; Loperamide; Piperidines | 1986 |
Effects of loperamide hydrochloride on experimental diarrhea and gastrointestinal myoelectrical activity in calves.
Topics: Abomasum; Animals; Cattle; Cattle Diseases; Colon; Diarrhea; Electromyography; Gastrointestinal Motility; Jejunum; Loperamide; Piperidines | 1987 |
Stimulation of gastrointestinal motility by loperamide in dogs.
Topics: Administration, Oral; Animals; Colon; Dogs; Gastrointestinal Motility; Injections, Intraventricular; Injections, Subcutaneous; Jejunum; Loperamide; Muscle Contraction; Naloxone; Piperidines; Pyloric Antrum | 1987 |
Influence of loperamide on the internal anal sphincter in the opossum.
Topics: Anal Canal; Animals; Drug Interactions; Electric Stimulation; Female; Isoproterenol; Loperamide; Male; Naloxone; Nicotine; Opossums; Piperidines; Pressure; Rectum; Spinal Nerve Roots; Verapamil | 1987 |
[Imodium].
Topics: Diarrhea; Humans; Loperamide; Piperidines | 1987 |
Ricinoleic acid and loperamide have opposite motor effects in the small and large intestine of the cat.
Topics: Animals; Cats; Colon; Female; Gastrointestinal Motility; Gastrointestinal Transit; Intestine, Small; Loperamide; Male; Oleic Acids; Piperidines; Ricinoleic Acids | 1987 |
Acute diarrhoeal disease in rabbit: bacteriological diagnosis and efficacy of oral rehydration in combination with loperamide hydrochloride.
Topics: Acute Disease; Animals; Combined Modality Therapy; Diarrhea; Fluid Therapy; Loperamide; Piperidines; Rabbits; Rodent Diseases | 1987 |
Loperamide: evidence for a centrally mediated opioid effect on rumen motility in conscious goats and sheep.
Topics: Animals; Domperidone; Gastrointestinal Motility; Goats; Kinetics; Loperamide; Naltrexone; Narcotics; Piperidines; Rumen; Sheep | 1986 |
Effect of loperamide on faecal control after rectoplasty for high imperforate anus.
Topics: Adolescent; Anal Canal; Anus, Imperforate; Child; Fecal Incontinence; Follow-Up Studies; Humans; Loperamide; Manometry; Piperidines; Postoperative Complications; Pressure; Rectum | 1986 |
Inhibitory actions of loperamide on absorptive processes in rat small intestine.
Topics: Animals; Biological Transport; Body Fluids; Fructose; Galactose; Glycine; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Kinetics; Loperamide; Male; Membrane Potentials; Morphine; Piperidines; Rats | 1986 |
Loperamide inhibits gallbladder inflammatory fluid secretion in experimental cholecystitis.
Topics: Animals; Cats; Cholecystitis; Disease Models, Animal; Female; Gallbladder; Loperamide; Male; Piperidines | 1986 |
Effects of amitraz, several opiate derivatives and anticholinergic agents on intestinal transit in ponies.
Topics: Animals; Atropine; Butorphanol; Colic; Gastrointestinal Motility; Glycopyrrolate; Horses; Loperamide; Morphinans; Narcotics; Parasympatholytics; Piperidines; Toluidines | 1986 |
Loperamide and oro-caecal transit delay.
Topics: Adult; Breath Tests; Cecum; Female; Humans; Loperamide; Male; Piperidines; Time Factors | 1986 |
Effect of dextromethorphan on guinea pig ileal contractility in vitro: comparison with levomethorphan, loperamide and codeine.
Topics: Actins; Adenosine Triphosphate; Animals; Calcium; Calmodulin; Codeine; Dextromethorphan; Electric Stimulation; Ileum; Levorphanol; Loperamide; Muscle Contraction; Myosins; Naloxone; Piperidines | 1986 |
Toddler diarrhoea: observations on the effects of aspirin and loperamide.
Topics: Antidiarrheals; Aspirin; Child, Preschool; Cyclooxygenase Inhibitors; Diarrhea; Diarrhea, Infantile; Humans; Infant; Loperamide; Piperidines; Prostaglandins F | 1985 |
Effect of loperamide and naloxone on mouth-to-caecum transit time evaluated by lactulose hydrogen breath test.
Topics: Adult; Breath Tests; Female; Gastrointestinal Motility; Humans; Hydrogen; Lactulose; Loperamide; Male; Naloxone; Piperidines | 1985 |
Different actions of 2 antidiarrheal agents, lidamidine and loperamide, on motility of the isolated cat colon muscle.
Topics: Animals; Antidiarrheals; Cats; Colon; Culture Techniques; Dose-Response Relationship, Drug; Electromyography; Female; Gastrointestinal Motility; Loperamide; Male; Phenylurea Compounds; Piperidines | 1985 |
[Effect of loperamide on 15-methyl-PGF2 alpha induced diarrhea and its uterine-stimulating action].
Topics: Animals; Carboprost; Diarrhea; Female; Loperamide; Male; Mice; Muscle Contraction; Piperidines; Rats; Uterine Contraction | 1985 |
Evaluation of gastrointestinal motility using the hydrogen breath test.
Topics: Adult; Breath Tests; Cisapride; Diphenoxylate; Female; Gastric Emptying; Gastrointestinal Motility; Humans; Hydrogen; Lactulose; Loperamide; Male; Metoclopramide; Piperidines; Random Allocation | 1985 |
Effects of loperamide on intestinal ion transport.
Topics: Animals; Calcimycin; Calcium; Chlorides; Cyclic AMP; Cyclic GMP; Dinoprostone; Ileum; Intestinal Mucosa; Ion Channels; Loperamide; Male; Piperidines; Prostaglandins E; Rabbits; Sodium; Stimulation, Chemical; Theophylline; Water-Electrolyte Balance | 1984 |
Loperamide-induced ileus.
Topics: Child, Preschool; Humans; Infant; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Loperamide; Piperidines | 1980 |
Confusion over loperamide.
Topics: Child; Diarrhea, Infantile; Humans; Loperamide; Piperidines | 1980 |
Loperamide in childhood diarrhoea.
Topics: Diarrhea, Infantile; Humans; Infant; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Loperamide; Piperidines | 1980 |
Loperamide in "toddler diarrhoea".
Topics: Child, Preschool; Diarrhea, Infantile; Humans; Infant; Loperamide; Piperidines | 1980 |
Loperamide overdose managed by naloxone.
Topics: Central Nervous System; Diarrhea, Infantile; Female; Humans; Infant; Loperamide; Naloxone; Piperidines | 1980 |
Influence of 1,8-dihydroxyanthraquinone and loperamide on the paracellular permeability across colonic mucosa.
Topics: Animals; Anthraquinones; Cell Membrane Permeability; Colon; Edetic Acid; Guinea Pigs; Intestinal Mucosa; Loperamide; Male; Piperidines; Technetium | 1981 |
Loperamide--what does it block?
Topics: Child; Diarrhea; Diarrhea, Infantile; Humans; Intestinal Mucosa; Loperamide; Piperidines; Receptors, Opioid | 1981 |
Loperamide and calmodulin.
Topics: Calcium-Binding Proteins; Calmodulin; Diarrhea; Humans; Loperamide; Phosphoric Diester Hydrolases; Piperidines | 1982 |
Loperamide therapy in a child with vipoma-associated diarrhoea.
Topics: Adenoma, Islet Cell; Diarrhea, Infantile; Female; Humans; Infant; Loperamide; Pancreatic Neoplasms; Piperidines; Vipoma | 1982 |
Naloxone prevents loperamide inhibition of neurotransmitter induced contractions in rat vas deferens.
Topics: Acetylcholine; Animals; Dopamine Antagonists; Loperamide; Male; Muscle Contraction; Muscle, Smooth; Naloxone; Neurotransmitter Agents; Norepinephrine; Piperidines; Rats; Vas Deferens | 1983 |
Loperamide: studies on its mechanism of action.
Topics: Adenylyl Cyclases; Animals; Cholera Toxin; Cyclic AMP; Dinoprostone; Intestinal Absorption; Intestinal Secretions; Jejunum; Loperamide; Male; Naloxone; Piperidines; Prostaglandins E; Rats; Rats, Inbred Strains | 1981 |
The action of loperamide in inhibiting prostaglandin-induced intestinal secretion in the rat.
Topics: Animals; Chlorides; Cyclic AMP; In Vitro Techniques; Intestinal Mucosa; Loperamide; Male; Membrane Potentials; Piperidines; Prostaglandin Antagonists; Rats; Sodium | 1981 |
Loperamide reduces the intestinal secretion but not the mucosal cAMP accumulation induced by choleratoxin.
Topics: Animals; Cholera Toxin; Cyclic AMP; Female; Intestinal Mucosa; Loperamide; Piperidines; Proteins; Rats; Rats, Inbred Strains | 1981 |
Increase of plasma corticosterone induced by loperamide in rats.
Topics: Adrenocorticotropic Hormone; Animals; Corticosterone; Female; Injections, Intraperitoneal; Injections, Intraventricular; Loperamide; Naloxone; Piperidines; Rats; Rats, Inbred Strains | 1982 |
Mechanisms of action of loperamide.
Topics: Animals; Body Water; Cholera Toxin; Cyclic AMP; Deoxycholic Acid; Diarrhea; Dinoprostone; Intestinal Mucosa; Jejunum; Loperamide; Piperidines; Prostaglandins E; Rats; Rats, Inbred Strains | 1983 |
Loperamide: evidence of interaction with mu and delta opioid receptors.
Topics: Animals; Female; Guinea Pigs; Ileum; Loperamide; Male; Mice; Morphine; Muscle Contraction; Myenteric Plexus; Piperidines; Rabbits; Rats; Receptors, Opioid; Receptors, Opioid, delta; Receptors, Opioid, mu; Vas Deferens | 1983 |
Opiate agonists and enterotoxins.
Topics: Animals; Cholera Toxin; Cyclic AMP; Diarrhea; Enkephalin, Methionine; Intestinal Mucosa; Loperamide; Male; Naloxone; Piperidines; Rats; Water-Electrolyte Balance | 1984 |
Inhibition by loperamide of deoxycholic acid induced intestinal secretion.
Topics: Animals; Colon; Cyclic AMP; Deoxycholic Acid; Erythritol; Female; Intestinal Absorption; Intestinal Mucosa; Intestinal Secretions; Jejunum; Loperamide; Metabolic Clearance Rate; Piperidines; Rats; Rats, Inbred Strains; Sodium-Potassium-Exchanging ATPase | 1984 |
Loperamide-induced inhibition of pancreatic secretion in rats.
Topics: Acetylcholine; Anesthesia; Animals; Bicarbonates; Cholecystokinin; Electric Stimulation; Glucose; Loperamide; Male; Naloxone; Pancreas; Pancreatic Fistula; Piperidines; Proteins; Rats; Rats, Inbred Strains; Vagus Nerve | 1984 |
Loperamide versus copamide.
Topics: Adult; Chlorpropamide; Diarrhea; Humans; Loperamide; Male; Medication Errors; Piperidines | 1984 |
Loperamide: blockade of calcium channels as a mechanism for antidiarrheal effects.
Topics: Animals; Antidiarrheals; Calcium; Calcium Channel Blockers; Guinea Pigs; Ileum; In Vitro Techniques; Intestinal Mucosa; Loperamide; Male; Muscle Contraction; Nifedipine; Nitrendipine; Piperidines; Tritium | 1984 |
Antisecretory activity of opiates in vitro and in vivo in man.
Topics: Animals; Chlorides; Diarrhea; Dinoprostone; Humans; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Loperamide; Morphine; Piperidines; Prostaglandins E; Rabbits; Time Factors; Toxins, Biological | 1983 |
Loperamide has antisecretory activity in the human jejunum in vivo.
Topics: Dinoprostone; Humans; Intestinal Absorption; Intestinal Mucosa; Jejunum; Loperamide; Perfusion; Piperidines; Prostaglandins E; Water-Electrolyte Balance | 1984 |
A suspected case of loperamide toxicity.
Topics: Humans; Infant, Newborn; Loperamide; Male; Naloxone; Piperidines | 1983 |
[Changes in water, glucose, and electrolyte transport in the rat intestine "in vivo" after intraluminal injection of loperamide and aspirin].
Topics: Animals; Aspirin; Biological Transport; Electrolytes; Glucose; Intestine, Small; Loperamide; Male; Piperidines; Rats; Rats, Inbred Strains; Water | 1983 |
Loperamide intoxication in a baby.
Topics: Diarrhea, Infantile; Humans; Infant; Loperamide; Male; Piperidines | 1983 |
[Ileus following the use of loperamide (Imodium)].
Topics: Aged; Antidiarrheals; Humans; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Loperamide; Male; Middle Aged; Piperidines | 1983 |
[Ileus following the use of loperamide (Imodium)].
Topics: Antidiarrheals; Humans; Intestinal Obstruction; Intestinal Pseudo-Obstruction; Loperamide; Male; Piperidines | 1983 |
Local inhibition of myoelectrical activity of human colon by loperamide.
Topics: Adult; Colon; Colon, Sigmoid; Depression, Chemical; Electrodes, Implanted; Electrophysiology; Gastrointestinal Motility; Humans; Intestinal Mucosa; Loperamide; Male; Middle Aged; Neostigmine; Piperidines; Time Factors | 1984 |
[Ileus following the use of loperamide (Imodium)].
Topics: Antidiarrheals; Humans; Intestinal Obstruction; Loperamide; Male; Middle Aged; Piperidines | 1984 |
Mechanism of the antidiarrheal effect of loperamide.
Topics: Adult; Antidiarrheals; Diarrhea; Electrolytes; Gastrointestinal Motility; Humans; Intestinal Absorption; Loperamide; Male; Piperidines; Polyethylene Glycols; Vasoactive Intestinal Peptide | 1984 |
Antidiarrhoeal activity of loperamide: studies of its influence on ion transport across rabbit ileal mucosa in vitro.
Topics: Animals; Bacterial Toxins; Biological Transport; Chlorides; Dinoprostone; Escherichia coli; Ileum; In Vitro Techniques; Intestinal Mucosa; Loperamide; Male; Membrane Potentials; Naloxone; Piperidines; Prostaglandins E; Rabbits; Sodium | 1982 |
Effect of loperamide, a peripheral opiate agonist, on circulating glucose, free fatty acids, insulin, C-peptide and pituitary hormones in healthy man.
Topics: Adult; Blood Glucose; C-Peptide; Fatty Acids, Nonesterified; Follicle Stimulating Hormone; Growth Hormone; Humans; Insulin; Loperamide; Luteinizing Hormone; Male; Middle Aged; Peptides; Piperidines; Pituitary Hormones; Placebos; Prolactin; Random Allocation | 1981 |
Loperamide in severe protracted diarrhoea.
Topics: Child, Preschool; Chronic Disease; Diarrhea, Infantile; Female; Humans; Infant; Jejunum; Loperamide; Male; Perfusion; Piperidines; Water | 1983 |
Loperamide toxicity in severe protracted diarrhoea.
Topics: Diarrhea, Infantile; Humans; Infant; Loperamide; Male; Piperidines; Seizures | 1983 |
Loperamide toxicity in an infant.
Topics: Gastroenteritis; Humans; Infant; Loperamide; Male; Piperidines | 1983 |
[Physical dependence on loperamide hydrochloride in mice and rats].
Topics: Administration, Oral; Animals; Antidiarrheals; Behavior, Animal; Body Weight; Dose-Response Relationship, Drug; Humans; Loperamide; Male; Mice; Piperidines; Rats; Rats, Inbred Strains; Substance-Related Disorders | 1982 |
Pharmaceutical review. Modium capsules.
Topics: Animals; Female; Humans; Loperamide; Piperidines; Pregnancy | 1980 |
Inhibition of postprandial pancreatic and biliary secretion by loperamide in patients with short bowel syndrome.
Topics: Adult; Aged; Bile; Bilirubin; Depression, Chemical; Female; Food; Humans; Loperamide; Malabsorption Syndromes; Male; Middle Aged; Pancreas; Piperidines; Short Bowel Syndrome; Trypsin | 1982 |
[Clinical results with loperamide in the treatment of chronic diarrhoea of varied aetiology (author's transl)].
Topics: Adult; Aged; Carcinoid Tumor; Chronic Disease; Colitis, Ulcerative; Crohn Disease; Diarrhea; Exocrine Pancreatic Insufficiency; Female; Humans; Loperamide; Male; Middle Aged; Piperidines; Short Bowel Syndrome; Time Factors | 1982 |
Loperamide in rat intestines: a unique disposition.
Topics: Animals; Duodenum; Ileum; In Vitro Techniques; Intestinal Absorption; Intestine, Small; Jejunum; Loperamide; Male; Piperidines; Rats; Rats, Inbred Strains | 1982 |
[Effects of several antidiarrheal agents on colon motility].
Topics: Adult; Antidiarrheals; Atropine; Colon; Diphenoxylate; Female; Gastrointestinal Motility; Humans; Isonipecotic Acids; Loperamide; Male; Piperidines | 1982 |
[Acute infectious diarrhea. Treatment with loperamide].
Topics: Adult; Animals; Bacterial Infections; Child; Diarrhea; Humans; Loperamide; Piperidines; Rats | 1981 |
[Neurological symptoms precipitated by loperamide (author's transl)].
Topics: Child, Preschool; Female; Humans; Infant; Loperamide; Male; Nervous System Diseases; Piperidines | 1980 |
Effect of loperamide and naloxone on gastric acid secretion in healthy man.
Topics: Adult; Female; Gastric Acid; Gastric Mucosa; Humans; Loperamide; Male; Middle Aged; Naloxone; Pentagastrin; Piperidines | 1981 |
The effect of loperamide on the ion fluxes across the isolated rabbit colon.
Topics: Animals; Biological Transport; Chlorides; Colon; In Vitro Techniques; Loperamide; Male; Piperidines; Rabbits; Sodium; Theophylline | 1981 |
Dependence liability of two antidiarrheals, nufenoxole and loperamide.
Topics: Adult; Antidiarrheals; Body Temperature; Electromyography; Humans; Loperamide; Male; Naloxone; Oxadiazoles; Piperidines; Pupil; Substance Withdrawal Syndrome; Substance-Related Disorders | 1980 |
[Loperamide poisoning in children].
Topics: Diarrhea, Infantile; Humans; Infant; Infant, Newborn; Loperamide; Piperidines | 1980 |
Aspirin or loperamide for childhood gastroenteritis.
Topics: Aspirin; Child; Gastroenteritis; Humans; Loperamide; Piperidines | 1980 |
Broad spectrum antiemetic effects of CP-122,721, a tachykinin NK1 receptor antagonist, in ferrets.
Topics: Animals; Antiemetics; Cisplatin; Copper Sulfate; Emetics; Ferrets; Ipecac; Loperamide; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Stereoisomerism; Vomiting | 1996 |
Relations between transit time, fermentation products, and hydrogen consuming flora in healthy humans.
Topics: Adult; Anti-Ulcer Agents; Antidiarrheals; Breath Tests; Cisapride; Euryarchaeota; Female; Gastrointestinal Motility; Humans; Lactulose; Loperamide; Male; Methane; Piperidines | 1996 |
Role of tachykinins in castor oil diarrhoea in rats.
Topics: Animals; Benzamides; Castor Oil; Colon; Diarrhea; Gastrointestinal Motility; Loperamide; Male; Naloxone; Piperidines; Quinuclidines; Rats; Tachykinins | 1997 |
Blood-brain barrier permeation: molecular parameters governing passive diffusion.
Topics: Air; Amiodarone; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Blood-Brain Barrier; Brain; Butyrophenones; Diffusion; Domperidone; Histamine H1 Antagonists; Humans; Kinetics; Loperamide; Micelles; Models, Biological; Piperidines; Surface Properties; Thermodynamics; Water | 1998 |
The role of cannabinoid receptors in intestinal motility, defaecation and diarrhoea in rats.
Topics: Analgesics; Animals; Antidiarrheals; Benzoxazines; Castor Oil; Cyclohexanols; Defecation; Diarrhea; Dose-Response Relationship, Drug; Gastrointestinal Motility; Gastrointestinal Transit; Loperamide; Male; Morpholines; Naphthalenes; Piperidines; Pyrazoles; Rats; Rats, Sprague-Dawley; Receptor, Cannabinoid, CB2; Receptors, Cannabinoid; Receptors, Drug; Rimonabant | 1999 |
The effect of the NK1 receptor antagonist CP-99,994 on emesis and c-fos protein induction by loperamide in the ferret.
Topics: Animals; Antidiarrheals; Brain Stem; Female; Ferrets; Loperamide; Male; Neurokinin-1 Receptor Antagonists; Piperidines; Proto-Oncogene Proteins c-fos; Psychomotor Performance; Vomiting | 2000 |
Spinal and peripheral mu opioids and the development of secondary tactile allodynia after thermal injury.
Topics: Administration, Topical; Analgesics, Opioid; Animals; Burns; Hindlimb; Hyperalgesia; Injections, Spinal; Loperamide; Male; Morphine; Naloxone; Narcotic Antagonists; Neural Pathways; Neurons, Afferent; Pain Threshold; Piperidines; Rats; Rats, Sprague-Dawley; Receptors, Opioid, mu; Remifentanil; Spinal Cord; Touch | 2002 |
Synthesis and smooth muscle-selective relaxant activity of a piperidine analogue: 1-(4'-fluorophenacyl)-4-hydroxy-4-phenyl-piperidinium chloride.
Topics: Acetylcholine; Animals; Antidiarrheals; Aorta, Thoracic; Calcium; Dose-Response Relationship, Drug; Heart; In Vitro Techniques; Intestines; Jejunum; Loperamide; Male; Muscle Relaxation; Muscle, Smooth; Muscle, Smooth, Vascular; Norepinephrine; Parasympatholytics; Piperidines; Rabbits; Spectrophotometry, Infrared; Spectrophotometry, Ultraviolet; Vasoconstrictor Agents; Vasodilator Agents | 2006 |
Novel trans-3,4-dimethyl-4-(3-hydroxyphenyl)piperidines as mu opioid receptor antagonists with improved opioid receptor selectivity profiles.
Topics: Administration, Oral; Animals; Cell Membrane; Central Nervous System; Chromatography, High Pressure Liquid; Diprenorphine; Gastrointestinal Transit; Guanosine 5'-O-(3-Thiotriphosphate); Humans; Loperamide; Mice; Molecular Structure; Piperidines; Receptors, Opioid, delta; Receptors, Opioid, kappa; Receptors, Opioid, mu; Structure-Activity Relationship | 2008 |
Cannabidiol, extracted from Cannabis sativa, selectively inhibits inflammatory hypermotility in mice.
Topics: Acetylcholine; Amidohydrolases; Animals; Cannabidiol; Cannabis; Cholinergic Agents; Croton Oil; Disease Models, Animal; Dose-Response Relationship, Drug; Enzyme Inhibitors; Gastrointestinal Agents; Gastrointestinal Motility; Gastrointestinal Transit; Ileitis; Ileum; Loperamide; Male; Mice; Mice, Inbred ICR; Piperidines; Pyrazoles; Receptor, Cannabinoid, CB1; Rimonabant | 2008 |
Effects of oral loperamide on efficacy of naltrexone, baclofen and AM-251 in blocking ethanol self-administration in rats.
Topics: Administration, Oral; Alcohol Deterrents; Alcohol Drinking; Animals; Animals, Outbred Strains; Baclofen; Behavior, Animal; Drug Synergism; Drug Therapy, Combination; GABA-B Receptor Agonists; Loperamide; Male; Naltrexone; Narcotic Antagonists; Piperidines; Pyrazoles; Rats; Rats, Wistar; Receptor, Cannabinoid, CB1; Receptors, Opioid, kappa; Receptors, Opioid, mu | 2012 |
A facile synthesis for novel loperamide analogs as potential μ opioid receptor agonists.
Topics: Humans; Ligands; Loperamide; Molecular Structure; Morphine; Piperidines; Receptors, Opioid, mu; Structure-Activity Relationship | 2012 |
Synthesis and characterization of [N-methyl-3H]loperamide.
Topics: Chemistry Techniques, Synthetic; Loperamide; Piperidines; Radiochemistry; Tritium | 2014 |
Lubeluzole: from anti-ischemic drug to preclinical antidiarrheal studies.
Topics: Animals; Anti-Bacterial Agents; Antidiarrheals; Bacteria; Colon; Diarrhea; Dose-Response Relationship, Drug; Gram-Negative Bacterial Infections; Gram-Positive Bacterial Infections; Guinea Pigs; Ileum; Loperamide; Male; Microbial Sensitivity Tests; Muscle Contraction; Neuroprotective Agents; Piperidines; Quaternary Ammonium Compounds; Rats; Rats, Sprague-Dawley; Thiazoles | 2021 |