loperamide and mannitol

loperamide has been researched along with mannitol in 7 studies

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19901 (14.29)18.7374
1990's1 (14.29)18.2507
2000's2 (28.57)29.6817
2010's3 (42.86)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, L; Humphreys, JE; Morgan, JB; Polli, JW; Serabjit-Singh, CS; Webster, LO; Wring, SA1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Buéno, L; Fioramonti, J; Hachet, T; Théodorou, V1
Ahsan, MA; Ilundain, A; Naftalin, RJ; Sandhu, BK; Smith, PM1
Costigan, C; Cox, EF; Garsed, KC; Gowland, PA; Hoad, CL; Marciani, L; Napolitano, A; Placidi, E; Pritchard, SE; Spiller, RC1

Reviews

1 review(s) available for loperamide and mannitol

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Trials

1 trial(s) available for loperamide and mannitol

ArticleYear
The effects of loperamide, or loperamide plus simethicone, on the distribution of gut water as assessed by MRI in a mannitol model of secretory diarrhoea.
    Alimentary pharmacology & therapeutics, 2012, Volume: 36, Issue:1

    Topics: Adult; Antidiarrheals; Antifoaming Agents; Body Water; Cross-Over Studies; Diarrhea; Double-Blind Method; Drug Therapy, Combination; Female; Gastrointestinal Motility; Humans; Intestinal Absorption; Intestine, Small; Loperamide; Magnetic Resonance Imaging; Male; Mannitol; Middle Aged; Simethicone; Young Adult

2012

Other Studies

5 other study(ies) available for loperamide and mannitol

ArticleYear
Rational use of in vitro P-glycoprotein assays in drug discovery.
    The Journal of pharmacology and experimental therapeutics, 2001, Volume: 299, Issue:2

    Topics: Adenosine Triphosphatases; Animals; ATP Binding Cassette Transporter, Subfamily B, Member 1; Cells, Cultured; Chromatography, Liquid; Enzyme Inhibitors; Fluoresceins; Fluorescent Dyes; Humans; Mass Spectrometry; Pharmacology; Spodoptera

2001
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Absorptive and motor components of the antidiarrhoeal action of loperamide: an in vivo study in pigs.
    Gut, 1991, Volume: 32, Issue:11

    Topics: Animals; Colon; Diarrhea; Digestion; Gastrointestinal Motility; Gastrointestinal Transit; Intestinal Absorption; Loperamide; Mannitol; Swine; Water

1991
Effects of theophylline, choleragen and loperamide on rabbit ileal fluid and electrolyte transport in vitro.
    British journal of pharmacology, 1987, Volume: 92, Issue:4

    Topics: Animals; Body Fluids; Bromides; Chlorides; Cholera Toxin; Electrolytes; Ileum; In Vitro Techniques; Intestinal Absorption; Intestinal Mucosa; Loperamide; Male; Mannitol; Osmolar Concentration; Piperidines; Rabbits; Theophylline

1987