loperamide has been researched along with loperamide oxide in 16 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 14 (87.50) | 18.2507 |
| 2000's | 2 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Donner, K; Ewe, K; Göke, M; Meyer zum Büschenfelde, KH | 1 |
| Adriaens, L; Emanuel, M; Huang, ML; Kamali, F; Rawlins, MD; Woestenborghs, R | 1 |
| Hofmeyr, GJ; Nikodem, VC | 1 |
| Castiglione, F; Gaupmann, G; Schneider, C; Stacher, G; Stacher-Janotta, G; Steinringer, H; Vacariu-Granser, GV; Weber, U | 1 |
| Goldhill, J; Hardcastle, J; Hardcastle, PT | 2 |
| Badhri, P; Beubler, E | 1 |
| Hendrickx, J; Heykants, J; Lavrijsen, K; Meuldermans, W; Monbaliu, J; van Dyck, D; van Houdt, J; Woestenborghs, R | 1 |
| Geerts, RJ; Heykants, JJ; Meuldermans, WE; Van Beijsterveldt, LE; Woestenborghs, RJ; Wuyts, K | 1 |
| Badhri, P; Beubler, E; Schirgi-Degen, A | 1 |
| Chatterton, BE; Horowitz, M; Muecke, T; Robb, T; Russo, A; Yeoh, EK | 1 |
| Dreverman, JW; Van der Poel, AJ | 1 |
| Huang, ML; Kamali, F | 1 |
| Read, NW; Sun, WM; Verlinden, M | 1 |
| Bodemar, G; Ragnarsson, G | 1 |
| Kalgutkar, AS; Nguyen, HT | 1 |
7 trial(s) available for loperamide and loperamide oxide
| Article | Year |
|---|---|
Influence of loperamide and loperamide oxide on the anal sphincter. A manometric study.
Topics: Adult; Anal Canal; Defecation; Double-Blind Method; Female; Humans; Loperamide; Male; Manometry; Pressure; Rectum | 1992 |
Dose proportionality study of loperamide following oral administration of loperamide oxide.
Topics: Administration, Oral; Adult; Analysis of Variance; Biological Availability; Biotransformation; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Loperamide; Male | 1992 |
Effects of the prodrug loperamide oxide, loperamide, and placebo on jejunal motor activity.
Topics: Administration, Oral; Adult; Double-Blind Method; Gastrointestinal Motility; Humans; Jejunum; Loperamide; Male; Prodrugs | 1992 |
Gastrointestinal function in chronic radiation enteritis--effects of loperamide-N-oxide.
Topics: Adult; Aged; Aged, 80 and over; Chronic Disease; Diarrhea; Digestive System; Double-Blind Method; Enteritis; Female; Humans; Loperamide; Male; Middle Aged; Radiation Injuries; Radiotherapy; Urogenital Neoplasms | 1993 |
Loperamide oxide in acute diarrhoea: a double-blind, placebo-controlled trial. The Dutch Diarrhoea Trialists Group.
Topics: Adolescent; Adult; Aged; Diarrhea; Double-Blind Method; Female; Follow-Up Studies; Humans; Loperamide; Male; Middle Aged; Time Factors; Treatment Outcome | 1995 |
Increased systemic availability of loperamide after oral administration of loperamide and loperamide oxide with cotrimoxazole.
Topics: Administration, Oral; Adult; Antidiarrheals; Biological Availability; Drug Administration Schedule; Half-Life; Humans; Loperamide; Male; Reference Values; Trimethoprim, Sulfamethoxazole Drug Combination | 1996 |
Effects of loperamide oxide on gastrointestinal transit time and anorectal function in patients with chronic diarrhoea and faecal incontinence.
Topics: Adult; Aged; Anal Canal; Chronic Disease; Cross-Over Studies; Diarrhea; Double-Blind Method; Fecal Incontinence; Female; Gastrointestinal Transit; Humans; Loperamide; Male; Middle Aged; Pressure; Rectum | 1997 |
9 other study(ies) available for loperamide and loperamide oxide
| Article | Year |
|---|---|
Secretion of the antidiarrhoeal agent loperamide oxide in breast milk.
Topics: Female; Humans; Loperamide; Milk, Human | 1992 |
The effect of loperamide oxide on prostaglandin-stimulated fluid transport in rat small intestine.
Topics: Animals; Body Fluids; Intestine, Small; Loperamide; Male; Prostaglandins; Rats | 1990 |
Comparison of the antisecretory effects of loperamide and loperamide oxide in the jejunum and the colon of rats in-vivo.
Topics: Administration, Oral; Animals; Colon; Dinoprostone; Female; Intestinal Mucosa; Intubation, Gastrointestinal; Jejunum; Loperamide; Naloxone; Prodrugs; Rats; Rats, Inbred Strains | 1990 |
Reduction of the prodrug loperamide oxide to its active drug loperamide in the gut of rats, dogs, and humans.
Topics: Animals; Dogs; Female; Germ-Free Life; Humans; Intestinal Absorption; Intestinal Mucosa; Intestines; Loperamide; Male; Oxidation-Reduction; Prodrugs; Rats; Rats, Inbred F344; Rats, Wistar | 1995 |
Gastrointestinal distribution of the prodrug loperamide oxide and its active drug loperamide in the dog.
Topics: Animals; Biological Availability; Digestive System; Dogs; Drug Administration Routes; Female; Intestinal Absorption; Intubation, Gastrointestinal; Loperamide; Male; Prodrugs; Tissue Distribution | 1995 |
Antisecretory activities of orally administered loperamide and loperamide oxide on intestinal secretion in rats.
Topics: Administration, Oral; Animals; Body Fluids; Colon; Dinoprostone; Dose-Response Relationship, Drug; Female; Jejunum; Loperamide; Prodrugs; Rats; Rats, Sprague-Dawley | 1993 |
Comparison of the effects of loperamide and loperamide oxide on absorptive processes in rat small intestine.
Topics: Animals; Electrophysiology; Glucose; Glycine; Intestinal Absorption; Intestine, Small; Loperamide; Male; Rats; Rats, Wistar; Sodium | 1993 |
Treatment of irritable bowel syndrome with loperamide oxide. An open study to determine optimal dosage.
Topics: Adult; Antidiarrheals; Colonic Diseases, Functional; Female; Humans; Loperamide; Male; Middle Aged; Pilot Projects; Treatment Outcome | 2000 |
Identification of an N-methyl-4-phenylpyridinium-like metabolite of the antidiarrheal agent loperamide in human liver microsomes: underlying reason(s) for the lack of neurotoxicity despite the bioactivation event.
Topics: 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine; 1-Methyl-4-phenylpyridinium; Animals; Antidiarrheals; Bupropion; Chromatography, High Pressure Liquid; Cytochrome P-450 Enzyme System; Dealkylation; Haloperidol; Humans; Hydroxylation; Ketoconazole; Loperamide; Male; Microsomes, Liver; NADP; Neurons; Pyridinium Compounds; Rats; Rats, Sprague-Dawley; Time Factors | 2004 |