loperamide and indomethacin

loperamide has been researched along with indomethacin in 16 studies

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-19904 (25.00)18.7374
1990's1 (6.25)18.2507
2000's4 (25.00)29.6817
2010's6 (37.50)24.3611
2020's1 (6.25)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Johans, C; Kinnunen, PK; Söderlund, T; Suomalainen, P1
Artursson, P; Bergström, CA; Hoogstraate, J; Matsson, P; Norinder, U; Pedersen, JM1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Artursson, P; Haglund, U; Karlgren, M; Kimoto, E; Lai, Y; Norinder, U; Vildhede, A; Wisniewski, JR1
Artursson, P; Mateus, A; Matsson, P1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Dranchak, PK; Huang, R; Inglese, J; Lamy, L; Oliphant, E; Queme, B; Tao, D; Wang, Y; Xia, M1
Leng-Peschlow, E1
Berger, E; Gerok, W; Haag, K; Knauf, H; Lübcke, R1
Burke, V; Gracey, M1
Hashimoto, K; Ishige, A; Kase, Y; Komatsu, Y; Makino, B; Saitoh, K1
Gillardin, JM; Girard, P; Lorette, I; Pansart, Y1
Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Ljungqvist, H; Middleton, B1

Reviews

1 review(s) available for loperamide and indomethacin

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016

Other Studies

15 other study(ies) available for loperamide and indomethacin

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Surface activity profiling of drugs applied to the prediction of blood-brain barrier permeability.
    Journal of medicinal chemistry, 2004, Mar-25, Volume: 47, Issue:7

    Topics: Blood-Brain Barrier; Lipid Bilayers; Micelles; Permeability; Pharmaceutical Preparations; Structure-Activity Relationship; Surface Properties

2004
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily B, Member 1; ATP Binding Cassette Transporter, Subfamily G, Member 2; ATP-Binding Cassette Transporters; Biological Transport; Cell Line; Computer Simulation; Cytochrome P-450 Enzyme System; Drug-Related Side Effects and Adverse Reactions; Estradiol; Humans; Insecta; Liver; Models, Molecular; Multidrug Resistance-Associated Protein 2; Multidrug Resistance-Associated Proteins; Neoplasm Proteins; Pharmaceutical Preparations; Pharmacology; Structure-Activity Relationship

2008
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Classification of inhibitors of hepatic organic anion transporting polypeptides (OATPs): influence of protein expression on drug-drug interactions.
    Journal of medicinal chemistry, 2012, May-24, Volume: 55, Issue:10

    Topics: Atorvastatin; Biological Transport; Drug Interactions; Estradiol; Estrone; HEK293 Cells; Heptanoic Acids; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; In Vitro Techniques; Least-Squares Analysis; Liver; Liver-Specific Organic Anion Transporter 1; Models, Molecular; Multivariate Analysis; Organic Anion Transporters; Organic Anion Transporters, Sodium-Independent; Protein Isoforms; Pyrroles; Solute Carrier Organic Anion Transporter Family Member 1B3; Structure-Activity Relationship; Transfection

2012
A high-throughput cell-based method to predict the unbound drug fraction in the brain.
    Journal of medicinal chemistry, 2014, Apr-10, Volume: 57, Issue:7

    Topics: Animals; Brain; Dialysis; HEK293 Cells; High-Throughput Screening Assays; Humans; Pharmaceutical Preparations; Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

2014
In vivo quantitative high-throughput screening for drug discovery and comparative toxicology.
    Disease models & mechanisms, 2023, 03-01, Volume: 16, Issue:3

    Topics: Animals; Caenorhabditis elegans; Drug Discovery; High-Throughput Screening Assays; Humans; Proteomics; Small Molecule Libraries

2023
Effect of sennosides and related compounds on intestinal transit in the rat.
    Pharmacology, 1988, Volume: 36 Suppl 1

    Topics: Animals; Anthraquinones; Calcium Channel Blockers; Cathartics; Female; Gastrointestinal Transit; Indomethacin; Loperamide; Pharmacology; Prodrugs; Rats; Rats, Inbred Strains; Senna Extract; Sennosides

1988
Determination of rheogenic ion transport in rat proximal colon in vivo.
    Pflugers Archiv : European journal of physiology, 1985, Volume: 405 Suppl 1

    Topics: Alprostadil; Amiloride; Animals; Biological Transport; Colon; Epithelium; Indomethacin; Ions; Kinetics; Loperamide; Male; Membrane Potentials; Rats; Rats, Inbred Strains; Theophylline

1985
Studies with enterotoxigenic microorganisms: effects of candidate antidiarrhoeals in experimental animals in vivo.
    Journal of pediatric gastroenterology and nutrition, 1984, Volume: 3, Issue:4

    Topics: Aluminum Hydroxide; Animals; Antidiarrheals; Aspirin; Bacterial Infections; Charcoal; Chlorpromazine; Cholestyramine Resin; Diarrhea; Drug Combinations; Enterotoxins; Indomethacin; Loperamide; Male; Niacinamide; Rats; Rats, Inbred Strains; Water-Electrolyte Balance

1984
Relationship between the antidiarrhoeal effects of Hange-Shashin-To and its active components.
    Phytotherapy research : PTR, 1999, Volume: 13, Issue:6

    Topics: Animals; Antidiarrheals; Castor Oil; Corticosterone; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diarrhea; Indomethacin; Isoenzymes; Japan; Loperamide; Male; Medicine, Kampo; Mice; Mice, Inbred ICR; Plant Extracts; Prostaglandin-Endoperoxide Synthases; Rats; Rats, Wistar

1999
Dose-response relationship and mechanism of action of Saccharomyces boulardii in castor oil-induced diarrhea in rats.
    Digestive diseases and sciences, 2003, Volume: 48, Issue:4

    Topics: Animals; Antidiarrheals; Arginine; Castor Oil; Diarrhea; Dose-Response Relationship, Drug; Fungal Vaccines; Indomethacin; Loperamide; Male; Naloxone; Probiotics; Rats; Rats, Wistar; Saccharomyces; Water-Electrolyte Balance

2003
Improved measurement of drug exposure in the brain using drug-specific correction for residual blood.
    Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2010, Volume: 30, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Antidiarrheals; Blood-Brain Barrier; Brain; Central Nervous System; Cerebrovascular Circulation; Chromatography, Liquid; Erythrocyte Volume; Hematocrit; Indomethacin; Loperamide; Male; Mass Spectrometry; Moxalactam; Pharmaceutical Preparations; Pharmacokinetics; Plasma; Rats; Rats, Sprague-Dawley; Reproducibility of Results

2010