loperamide and codeine

loperamide has been researched along with codeine in 19 studies

Research

Studies (19)

TimeframeStudies, this research(%)All Research%
pre-199012 (63.16)18.7374
1990's1 (5.26)18.2507
2000's2 (10.53)29.6817
2010's3 (15.79)24.3611
2020's1 (5.26)2.80

Authors

AuthorsStudies
Creveling, CR; Daly, JW; Lewandowski, GA; McNeal, ET1
Ahlin, G; Artursson, P; Bergström, CA; Gustavsson, L; Karlsson, J; Larsson, R; Matsson, P; Norinder, U; Pedersen, JM1
Antonsson, M; Bengtsson, O; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Jerndal, G; Wan, H; Winiwarter, S1
Barnes, JC; Bradley, P; Day, NC; Fourches, D; Reed, JZ; Tropsha, A1
Ahlin, G; Bergström, F; Bredberg, U; Fridén, M; Hammarlund-Udenaes, M; Rehngren, M; Wan, H1
Chen, M; Hu, C; Suzuki, A; Thakkar, S; Tong, W; Yu, K1
Heykants, JJ; Janssen, PA; McGuire, JL; Niemegeers, CJ1
Farthing, MJ; Lennard-Jones, JE; Rodrigues, CA; Thompson, DG1
Burnham, WR; McIntyre, A; O'Brien, JD; Thompson, DG; Walker, E1
Gaginella, TS; Kachur, JF; Morgan, DW1
Bondarev, IuA; Nikitin, AM1
Robertson, HD1
Green, J; Jaffe, JH; Kanzler, M2
Pounder, RE; Shee, CD1
Corbett, CL; Holdsworth, CD; Palmer, KR1
Hill, GL; King, RF; Norton, T1
Agachan, F; Alabaz, O; Billotti, VL; Daniel, N; Nessim, A; Nogueras, JJ; Weiss, EG; Wexner, SD1
Goryński, K; Sobczak, Ł1

Reviews

3 review(s) available for loperamide and codeine

ArticleYear
DILIrank: the largest reference drug list ranked by the risk for developing drug-induced liver injury in humans.
    Drug discovery today, 2016, Volume: 21, Issue:4

    Topics: Chemical and Drug Induced Liver Injury; Databases, Factual; Drug Labeling; Humans; Pharmaceutical Preparations; Risk

2016
[Problems with ileostomies (review of the literature)].
    Khirurgiia, 1984, Issue:8

    Topics: Atropine; Cicatrix; Codeine; Constriction, Pathologic; Diet; Diphenoxylate; Drug Combinations; Gastrointestinal Motility; Humans; Ileostomy; Intestinal Diseases; Loperamide; Magnetics; Peristalsis; Postoperative Complications; Rehabilitation, Vocational; Social Adjustment; Water-Electrolyte Imbalance

1984
Pharmacological Aspects of Over-the-Counter Opioid Drugs Misuse.
    Molecules (Basel, Switzerland), 2020, Aug-27, Volume: 25, Issue:17

    Topics: Analgesics, Opioid; Codeine; Drug Misuse; Humans; Loperamide; Nonprescription Drugs

2020

Trials

5 trial(s) available for loperamide and codeine

ArticleYear
Loperamide, diphenoxylate, and codeine phosphate in chronic diarrhoea.
    British medical journal, 1980, Feb-23, Volume: 280, Issue:6213

    Topics: Chronic Disease; Clinical Trials as Topic; Codeine; Diarrhea; Diphenoxylate; Double-Blind Method; Humans; Isonipecotic Acids; Loperamide; Piperidines

1980
Double-blind cross-over study comparing loperamide, codeine and diphenoxylate in the treatment of chronic diarrhea.
    Gastroenterology, 1980, Volume: 79, Issue:6

    Topics: Antidiarrheals; Chronic Disease; Clinical Trials as Topic; Codeine; Diarrhea; Diphenoxylate; Double-Blind Method; Humans; Isonipecotic Acids; Loperamide; Piperidines; Random Allocation; Time Factors

1980
A double-blind crossover study of the effect of loperamide hydrochloride and codeine phosphate on ileostomy output.
    The Australian and New Zealand journal of surgery, 1982, Volume: 52, Issue:2

    Topics: Adult; Aged; Body Weight; Clinical Trials as Topic; Codeine; Diarrhea; Double-Blind Method; Electrolytes; Female; Humans; Ileostomy; Loperamide; Male; Middle Aged; Nausea; Piperidines; Postoperative Complications; Potassium; Sodium

1982
Abuse potential of loperamide.
    Clinical pharmacology and therapeutics, 1980, Volume: 28, Issue:6

    Topics: Adult; Codeine; Humans; Loperamide; Male; Naloxone; Piperidines; Pupil; Substance-Related Disorders

1980
Is bowel confinement necessary after anorectal reconstructive surgery? A prospective, randomized, surgeon-blinded trial.
    Diseases of the colon and rectum, 1999, Volume: 42, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Anal Canal; Codeine; Defecation; Diet Therapy; Double-Blind Method; Fecal Incontinence; Female; Humans; Loperamide; Male; Middle Aged; Plastic Surgery Procedures; Postoperative Care; Postoperative Complications; Prospective Studies; Rectal Fistula; Rectum; Treatment Outcome

1999

Other Studies

11 other study(ies) available for loperamide and codeine

ArticleYear
[3H]Batrachotoxinin A 20 alpha-benzoate binding to voltage-sensitive sodium channels: a rapid and quantitative assay for local anesthetic activity in a variety of drugs.
    Journal of medicinal chemistry, 1985, Volume: 28, Issue:3

    Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Anesthetics, Local; Animals; Batrachotoxins; Calcium Channel Blockers; Cyclic AMP; Guinea Pigs; Histamine H1 Antagonists; In Vitro Techniques; Ion Channels; Neurotoxins; Sodium; Tranquilizing Agents; Tritium

1985
Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.
    Journal of medicinal chemistry, 2008, Oct-09, Volume: 51, Issue:19

    Topics: Cell Line; Computer Simulation; Drug Design; Gene Expression Profiling; Humans; Hydrogen Bonding; Liver; Molecular Weight; Organic Cation Transporter 1; Pharmaceutical Preparations; Predictive Value of Tests; Reverse Transcriptase Polymerase Chain Reaction; RNA, Messenger; Structure-Activity Relationship

2008
Structure-brain exposure relationships in rat and human using a novel data set of unbound drug concentrations in brain interstitial and cerebrospinal fluids.
    Journal of medicinal chemistry, 2009, Oct-22, Volume: 52, Issue:20

    Topics: Animals; Blood-Brain Barrier; Brain; Extracellular Fluid; Humans; Linear Models; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley

2009
Cheminformatics analysis of assertions mined from literature that describe drug-induced liver injury in different species.
    Chemical research in toxicology, 2010, Volume: 23, Issue:1

    Topics: Animals; Chemical and Drug Induced Liver Injury; Cluster Analysis; Databases, Factual; Humans; MEDLINE; Mice; Models, Chemical; Molecular Conformation; Quantitative Structure-Activity Relationship

2010
Measurement of unbound drug exposure in brain: modeling of pH partitioning explains diverging results between the brain slice and brain homogenate methods.
    Drug metabolism and disposition: the biological fate of chemicals, 2011, Volume: 39, Issue:3

    Topics: Animals; Biological Transport; Brain; Chemical Phenomena; Dialysis; Hydrogen-Ion Concentration; In Vitro Techniques; Lysosomes; Male; Models, Biological; Pharmaceutical Preparations; Pharmacokinetics; Rats; Rats, Sprague-Dawley; Reproducibility of Results; Tissue Distribution

2011
Dissociation between opiate-like and antidiarrheal activities of antidiarrheal drugs.
    The Journal of pharmacology and experimental therapeutics, 1979, Volume: 210, Issue:3

    Topics: Administration, Oral; Animals; Antidiarrheals; Bridged Bicyclo Compounds; Castor Oil; Codeine; Diphenoxylate; Dose-Response Relationship, Drug; Injections, Intravenous; Lethal Dose 50; Loperamide; Male; Morphine; Narcotics; Oxadiazoles; Rats; Reaction Time

1979
The effects of octreotide, soy polysaccharide, codeine and loperamide on nutrient, fluid and electrolyte absorption in the short-bowel syndrome.
    Alimentary pharmacology & therapeutics, 1989, Volume: 3, Issue:2

    Topics: Codeine; Drug Therapy, Combination; Electrolytes; Gastrointestinal Transit; Humans; Intestinal Absorption; Loperamide; Octreotide; Polysaccharides; Short Bowel Syndrome

1989
Effect of codeine and loperamide on upper intestinal transit and absorption in normal subjects and patients with postvagotomy diarrhoea.
    Gut, 1988, Volume: 29, Issue:3

    Topics: Adult; Aged; Chronic Disease; Codeine; Diarrhea; Female; Gastrointestinal Transit; Glucose; Humans; Intestinal Absorption; Loperamide; Male; Middle Aged; Piperidines; Vagotomy

1988
Effect of dextromethorphan on guinea pig ileal contractility in vitro: comparison with levomethorphan, loperamide and codeine.
    The Journal of pharmacology and experimental therapeutics, 1986, Volume: 239, Issue:3

    Topics: Actins; Adenosine Triphosphate; Animals; Calcium; Calmodulin; Codeine; Dextromethorphan; Electric Stimulation; Ileum; Levorphanol; Loperamide; Muscle Contraction; Myosins; Naloxone; Piperidines

1986
Use of an elemental diet as a nutritionally complete "medical colostomy".
    Southern medical journal, 1983, Volume: 76, Issue:8

    Topics: Adolescent; Adult; Catheters, Indwelling; Child; Child, Preschool; Codeine; Colostomy; Diphenoxylate; Fecal Incontinence; Female; Food Additives; Food, Formulated; Humans; Infant; Loperamide; Male; Middle Aged; Organic Chemicals

1983
Abuse potential of loperamide: adaptation of established evaluative methods to volunteer subjects.
    NIDA research monograph, 1981, Volume: 34

    Topics: Codeine; Dose-Response Relationship, Drug; Double-Blind Method; Humans; Kinetics; Loperamide; Placebos; Prisons; Reflex, Pupillary; Substance-Related Disorders

1981