lonidamine has been researched along with lactic acid in 10 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (60.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 2 (20.00) | 29.6817 |
| 2010's | 1 (10.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| De Martino, C; Floridi, A; Malorni, W; Marcante, ML; Nista, A; Silvestrini, B | 1 |
| Caputo, A; Carapella, CM; Del Carlo, C; Fanciulli, M; Floridi, A; Giorno, S; Paggi, MG; Silvestrini, B; Zupi, G | 1 |
| De Martino, C; Malorni, W; Marolla, A; Natali, PG; Nista, A; Salsano, F; Viora, M | 1 |
| Battelli, T; D'Atri, S; De Martino, C; Floridi, A; Gallo, M; Malorni, W; Marcante, ML; Nista, A; Paggi, MG | 1 |
| Evans, WK; Mullis, B; Shepherd, FA | 1 |
| Cioli, V; Citro, G; D'Atri, S; De Martino, C; Feriozzi, R; Floridi, A; Marcante, ML; Menichini, R | 1 |
| Ben-Yoseph, O; Lyons, JC; Ross, BD; Song, CW | 1 |
| Bruno, T; Di Padova, M; Fanciulli, M; Floridi, A; Gentile, FP; Giovannelli, A; Rubiu, O | 1 |
| Kaplan, O | 1 |
| Blair, IA; Glickson, JD; Guo, L; Halestrap, AP; Leeper, DB; Nancolas, B; Nath, K; Nelson, DS; Zhou, R | 1 |
10 other study(ies) available for lonidamine and lactic acid
| Article | Year |
|---|---|
Effect of lonidamine on the aerobic glycolysis of normal and phytohemagglutinin-stimulated human peripheral blood lymphocytes.
Topics: Cell Survival; Glycolysis; Hexokinase; Humans; Indazoles; Lactates; Lactic Acid; Lymphocyte Activation; Lymphocytes; Mitochondrial Swelling; Ouabain; Phosphofructokinase-1; Phytohemagglutinins; Pyrazoles | 1985 |
Effect of lonidamine on human malignant gliomas: biochemical studies.
Topics: Astrocytoma; Deoxy Sugars; Deoxyglucose; Glycolysis; Hexokinase; Humans; Indazoles; Lactates; Lactic Acid; Pyrazoles; Tumor Cells, Cultured | 1988 |
Inhibition of aerobic glycolysis in normal and neoplastic lymphoid cells induced by Lonidamine [1-(2,4-dichlorobenzyl)-I-H-indazol-3-carboxylic acid].
Topics: Aerobiosis; B-Lymphocytes; Dose-Response Relationship, Drug; Glycolysis; Humans; In Vitro Techniques; Indazoles; Lactates; Lactic Acid; Leukemia; Microscopy, Electron; Phenotype; Pyrazoles; T-Lymphocytes | 1984 |
Effects of Lonidamine on murine and human tumor cells in vitro. A morphological and biochemical study.
Topics: Animals; Carcinoma, Ehrlich Tumor; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Indazoles; Lactates; Lactic Acid; Leukemia, Experimental; Male; Mice; Mice, Inbred Strains; Microscopy, Electron; Microscopy, Electron, Scanning; Mitochondria; Neoplasms; Pyrazoles; Rats; Rats, Inbred Strains; Time Factors | 1984 |
Phase II evaluation of Lonidamine in patients with advanced malignancy.
Topics: Adult; Aged; Antineoplastic Agents; Auditory Perception; Digestive System; Drug Evaluation; Female; Humans; Indazoles; Lactates; Lactic Acid; Male; Middle Aged; Muscles; Neoplasms; Pyrazoles; Testosterone; Time Factors | 1984 |
Energy metabolism of normal and lonidamine-treated Sertoli cells of rats.
Topics: Aerobiosis; Animals; Antispermatogenic Agents; Cells, Cultured; Energy Metabolism; Glucose; Indazoles; Lactates; Lactic Acid; Male; Microscopy, Electron; Oxygen Consumption; Pyrazoles; Rats; Sertoli Cells | 1983 |
Mechanism of action of lonidamine in the 9L brain tumor model involves inhibition of lactate efflux and intracellular acidification.
Topics: Animals; Antineoplastic Agents; Brain Neoplasms; Gliosarcoma; Hydrogen-Ion Concentration; Indazoles; Injections, Subcutaneous; Intracellular Fluid; Lactic Acid; Magnetic Resonance Spectroscopy; Male; Muscle Neoplasms; Neoplasm Transplantation; Phosphorus Radioisotopes; Rats; Rats, Inbred F344; Thigh | 1998 |
Energy metabolism of human LoVo colon carcinoma cells: correlation to drug resistance and influence of lonidamine.
Topics: Adenosine Triphosphate; Antineoplastic Agents; Carbon Dioxide; Cell Division; Citrate (si)-Synthase; Colonic Neoplasms; Dose-Response Relationship, Drug; Doxorubicin; Drug Resistance, Neoplasm; Energy Metabolism; Glucose; Hexokinase; Humans; Indazoles; Inhibitory Concentration 50; Isocitrate Dehydrogenase; Kinetics; Lactic Acid; Tumor Cells, Cultured | 2000 |
Correspondence re: M. Fanciulli et al., Energy metabolism of human LoVo colon carcinoma cells: correlation to drug resistance and influence fo lonidamine. Clin. Cancer Res., 6: 1590-1597, 2000.
Topics: Antineoplastic Agents; Colonic Neoplasms; Drug Resistance, Neoplasm; Glycolysis; Hexokinase; Humans; Indazoles; Lactic Acid; Tumor Cells, Cultured | 2000 |
The anti-tumour agent lonidamine is a potent inhibitor of the mitochondrial pyruvate carrier and plasma membrane monocarboxylate transporters.
Topics: Animals; Antineoplastic Agents; Carrier Proteins; Cell Membrane; Indazoles; Ion Transport; Lactic Acid; Male; Membrane Transport Proteins; Mitochondrial Proteins; Monocarboxylic Acid Transporters; Pyruvic Acid; Rats; Rats, Wistar; Solute Carrier Proteins; Symporters | 2016 |