lonafarnib has been researched along with u 0126 in 1 studies
| Studies (lonafarnib) | Trials (lonafarnib) | Recent Studies (post-2010) (lonafarnib) | Studies (u 0126) | Trials (u 0126) | Recent Studies (post-2010) (u 0126) |
|---|---|---|---|---|---|
| 224 | 34 | 90 | 2,816 | 2 | 1,213 |
| Protein | Taxonomy | lonafarnib (IC50) | u 0126 (IC50) |
|---|---|---|---|
| RAF proto-oncogene serine/threonine-protein kinase | Homo sapiens (human) | 0.29 | |
| Serine/threonine-protein kinase B-raf | Homo sapiens (human) | 0.25 | |
| Amine oxidase [flavin-containing] B | Rattus norvegicus (Norway rat) | 0.07 | |
| Dual specificity mitogen-activated protein kinase kinase 2 | Homo sapiens (human) | 0.2816 | |
| Dual specificity mitogen-activated protein kinase kinase 1 | Homo sapiens (human) | 0.2529 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bishop, WR; Brassard, DL; English, JM; Kirschmeier, P; Malkowski, M; Nagabhushan, TL | 1 |
1 other study(ies) available for lonafarnib and u 0126
| Article | Year |
|---|---|
Inhibitors of farnesyl protein transferase and MEK1,2 induce apoptosis in fibroblasts transformed with farnesylated but not geranylgeranylated H-Ras.
Topics: Alkyl and Aryl Transferases; Animals; Apoptosis; Butadienes; Cell Line; Cell Line, Transformed; Enzyme Inhibitors; Fibroblasts; Flavonoids; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Mitogen-Activated Protein Kinase Kinases; Mitogen-Activated Protein Kinases; Nitriles; Phosphorylation; Piperidines; Protein Prenylation; Protein Serine-Threonine Kinases; Protein-Tyrosine Kinases; Proto-Oncogene Proteins p21(ras); Pyridines; Rats | 2002 |