Page last updated: 2024-09-04

lonafarnib and mevalonic acid

lonafarnib has been researched along with mevalonic acid in 3 studies

Compound Research Comparison

Studies (lonafarnib)	Trials (lonafarnib)	Recent Studies (post-2010) (lonafarnib)	Studies (mevalonic acid)	Trials (mevalonic acid)	Recent Studies (post-2010) (mevalonic acid)
224	34	90	3,810	33	922

Research

Studies (3)

Timeframe	Studies, this research(%)	All Research%
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	3 (100.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80

Authors

Authors	Studies
Armstrong, L; Ashar, HR; Bishop, WR; Black, S; Carr, D; Gray, K; James, L; Kirschmeier, P	1
Abbruzzese, A; Budillon, A; Caponigro, F; Caraglia, M; Marra, M; Tagliaferri, P	1
Baulch-Brown, C; Ma, D; Molloy, TJ; Spencer, A; Yeh, SL	1

Reviews

1 review(s) available for lonafarnib and mevalonic acid

Article	Year
Isoprenylation of intracellular proteins as a new target for the therapy of human neoplasms: preclinical and clinical implications. Current drug targets, 2005, Volume: 6, Issue:3 Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Benzodiazepines; Farnesyltranstransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Mevalonic Acid; Neoplasms; Phosphatidylinositol 3-Kinases; Piperidines; Protein Prenylation; Protein Processing, Post-Translational; Pyridines; Quinolones; ras Proteins	2005

Article

Year

Isoprenylation of intracellular proteins as a new target for the therapy of human neoplasms: preclinical and clinical implications.

Current drug targets, 2005, Volume: 6, Issue:3

Topics: Alkyl and Aryl Transferases; Animals; Antineoplastic Agents; Benzodiazepines; Farnesyltranstransferase; Humans; Hydroxymethylglutaryl-CoA Reductase Inhibitors; Imidazoles; Mevalonic Acid; Neoplasms; Phosphatidylinositol 3-Kinases; Piperidines; Protein Prenylation; Protein Processing, Post-Translational; Pyridines; Quinolones; ras Proteins

2005

Other Studies

2 other study(ies) available for lonafarnib and mevalonic acid

Article	Year
Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules. The Journal of biological chemistry, 2000, Sep-29, Volume: 275, Issue:39 Topics: Alkyl and Aryl Transferases; Cell Cycle; Chromosomal Proteins, Non-Histone; Enzyme Inhibitors; Humans; Mevalonic Acid; Microfilament Proteins; Microtubule-Associated Proteins; Microtubules; Piperidines; Protein Prenylation; Pyridines; Substrate Specificity; Tumor Cells, Cultured	2000
Inhibitors of the mevalonate pathway as potential therapeutic agents in multiple myeloma. Leukemia research, 2007, Volume: 31, Issue:3 Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diphosphonates; Drug Screening Assays, Antitumor; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Imidazoles; Indoles; Mevalonic Acid; Multiple Myeloma; Piperidines; Pyridines; Structure-Activity Relationship; Zoledronic Acid	2007

Article

Year

Farnesyl transferase inhibitors block the farnesylation of CENP-E and CENP-F and alter the association of CENP-E with the microtubules.

The Journal of biological chemistry, 2000, Sep-29, Volume: 275, Issue:39

Topics: Alkyl and Aryl Transferases; Cell Cycle; Chromosomal Proteins, Non-Histone; Enzyme Inhibitors; Humans; Mevalonic Acid; Microfilament Proteins; Microtubule-Associated Proteins; Microtubules; Piperidines; Protein Prenylation; Pyridines; Substrate Specificity; Tumor Cells, Cultured

2000

Inhibitors of the mevalonate pathway as potential therapeutic agents in multiple myeloma.

Leukemia research, 2007, Volume: 31, Issue:3

Topics: Apoptosis; Apoptosis Regulatory Proteins; Cell Cycle; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diphosphonates; Drug Screening Assays, Antitumor; Fatty Acids, Monounsaturated; Fluvastatin; Humans; Imidazoles; Indoles; Mevalonic Acid; Multiple Myeloma; Piperidines; Pyridines; Structure-Activity Relationship; Zoledronic Acid

2007