lonafarnib has been researched along with fti 277 in 2 studies
| Studies (lonafarnib) | Trials (lonafarnib) | Recent Studies (post-2010) (lonafarnib) | Studies (fti 277) | Trials (fti 277) | Recent Studies (post-2010) (fti 277) |
|---|---|---|---|---|---|
| 224 | 34 | 90 | 5 | 0 | 3 |
| 224 | 34 | 90 | 118 | 0 | 23 |
| Protein | Taxonomy | lonafarnib (IC50) | fti 277 (IC50) |
|---|---|---|---|
| Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | Homo sapiens (human) | 0.0202 | |
| Protein farnesyltransferase subunit beta | Homo sapiens (human) | 0.0202 |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Buuh, ZY; Lyu, Z; Wang, RE | 1 |
| Adjei, AA; Davis, JN; Erlichman, C; Kaufmann, SH; Svingen, PA | 1 |
1 review(s) available for lonafarnib and fti 277
| Article | Year |
|---|---|
Interrogating the Roles of Post-Translational Modifications of Non-Histone Proteins.
Topics: Acetylation; Animals; Citrullination; Enzyme Inhibitors; Glycosylation; Humans; Methylation; Phosphorylation; Protein Prenylation; Protein Processing, Post-Translational; Proteins; Ubiquitination | 2018 |
1 other study(ies) available for lonafarnib and fti 277
| Article | Year |
|---|---|
Comparison of potential markers of farnesyltransferase inhibition.
Topics: Alkyl and Aryl Transferases; Amino Acid Sequence; Antineoplastic Agents; Biomarkers, Tumor; Carrier Proteins; Cyclin-Dependent Kinase Inhibitor p21; Cyclins; Dose-Response Relationship, Drug; Electrophoresis, Polyacrylamide Gel; Enzyme Inhibitors; Farnesyltranstransferase; Heat-Shock Proteins; HSP40 Heat-Shock Proteins; Humans; Immunoblotting; Immunohistochemistry; Inhibitory Concentration 50; Lamin Type A; Lamins; Methionine; Molecular Sequence Data; Nuclear Proteins; Peptides; Piperidines; Protein Precursors; Protein Prenylation; Pyridines; Signal Transduction; Transfection; Tumor Cells, Cultured | 2000 |